CN106729209A - A kind of medicine for treating rheumatism - Google Patents

A kind of medicine for treating rheumatism Download PDF

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Publication number
CN106729209A
CN106729209A CN201611203693.XA CN201611203693A CN106729209A CN 106729209 A CN106729209 A CN 106729209A CN 201611203693 A CN201611203693 A CN 201611203693A CN 106729209 A CN106729209 A CN 106729209A
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parts
root
rheumatism
medicine
raw material
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陈权
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237Notopterygium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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Abstract

The invention discloses a kind of medicine for treating rheumatism, belong to drug preparation technique field.It is made up of following raw material by weight:8~15 parts of Ramulus Taxilli, 8~12 parts of the red sage root, 4~8 parts of the bighead atractylodes rhizome, 6~10 parts of rhizoma homalonemae, 2~5 parts of fructus viticis, 5~8 parts of notopterygium root, 3~6 parts of asarum, 3~5 parts of the Radix Astragali, 3~7 parts of smilax, 7~10 parts of earthworm, 7~10 parts of the root of bidentate achyranthes, 4~7 parts of the bark of eucommia.The medicine of present invention treatment rheumatism, from natural plants as raw material, rheumatism is treated using the comprehensive function of each raw material components, toxic and side effect is small, and it is cheap, the effects such as with kidney and spleen invigorating, clearing heat and detoxicating, channels sootheing and network vessel quickening, tonifying kidney and benefiting sperm, the effect treated both principal and secondary aspect of disease can be reached, it is adaptable to the treatment of the disease such as rheumatism, rheumatoid arthritis.

Description

A kind of medicine for treating rheumatism
Technical field
The invention belongs to drug preparation technique field, more particularly to a kind of medicine for treating rheumatism.
Background technology
Rheumatism is a kind of common disease, broadly thinks that every disease for causing Bones and joints, myalgia can all return It is rheumatism to belong to.The pathogenic factor of rheumatism main at present has following several 1, risk factor:Cold, moistening, tired, nutrition Bad, wound, mental element etc., are the factors for inducing rheumatism, can often be looked into without obvious inducement before Most patients.2nd, it is immunized anti- Should:The stimulation that body exogenous or endogenous antigen material are presented directly or by macrophage, makes corresponding T- cell activations, Some T-cell produces a large amount of various inflammation cytokines to cause the different degrees of damage or destruction of various organization organ;Part T- cell reactivation B- cells, produce lot of antibodies, directly or with antigen binding form immune complex, receive tissue or organ To damage or destruction.3rd, genetic background:Research in recent years has shown that some rheumatic diseases, particularly CTD, heredity And the neurological susceptibility of patient is closely related with the expression of disease, early stage to disease or case is not true to type and prognosis has certain meaning Justice.Rheumatoid arthritis, ankylosing spondylitis have genetic predisposition, and gout, rheumatic fever and inherent cause also have substantial connection.4、 Infective agent:Illustrated according to research for many years, the multi-infection factor, antigen or super antigen that microorganism produces can be direct Or excite or start immune response indirectly.5th, endocrine factor:Research has shown that, the imbalance of estrogen and progestational hormone and various wind The generation of diseases caused by dampness is relevant.6th, environment and physical factor:The long-term people worked in frost storehouse, because of wind-cold damp pathogen invasion and attack, joint is normal Contact cold water, catches cold and endures cold, if do not noted, plus is poor constitution, is the generation for being very easy to cause rheumatic arthritis.Life There is certain initiation to rheumatism with the environment of work, the people for often being worked in cold environment it is certain it is noted that.Rheumatism The cause of disease and cold, dark, moist, sweat after when the environmental factors such as wind it is closely related.7th, cargo work is born:The appearance of strain of joint It is the key foundation of rheumatism morbidity, if what the long-term people for being worked overloadingly should be noted, must active defense wind Wet infringement, is the cause of disease of common rheumatism.8th, other paathogenic factors:Bruise, joint sprain, external force damage, bacterium, virus, body Weaker picture puerpera of matter etc., easily triggers the generation of rheumatism.
At present, the Western medicine dependence for the treatment of rheumatism is big, costly, there is side effect, can have loss to liver kidney work(, takes stopgap measures Do not effect a permanent cure, Relapse rate recurrence, bad influence is caused on patients ' psychological sometimes.And middle the effective elements of the medicine is not easy to lose, pair is made With small, Chinese medicinal formulae can at any time be added and subtracted because of disease, because of the difference of disease, and treatment diseases range is wider.People are to effectively treatment rheumatism Chinese medicine there is great demand.
The content of the invention
It is an object of the invention to provide a kind of medicine for treating rheumatism, with scattered wind clearing damp, kidney and spleen invigorating, strong muscle The effects such as bone, replenishing qi and blood.
The technical scheme is that:A kind of medicine for treating rheumatism, is made up of following raw material by weight:Ramulus Taxilli 8~15 parts, 8~12 parts of the red sage root, 4~8 parts of the bighead atractylodes rhizome, 6~10 parts of rhizoma homalonemae, 2~5 parts of fructus viticis, 5~8 parts of notopterygium root, asarum 3~6 Part, 3~5 parts of the Radix Astragali, 3~7 parts of smilax, 7~10 parts of earthworm, 7~10 parts of the root of bidentate achyranthes, 4~7 parts of the bark of eucommia.
Further, it is made up of following raw material by weight:12~14 parts of Ramulus Taxilli, 8~10 parts of the red sage root, 5~7 parts of the bighead atractylodes rhizome, 7~9 parts of rhizoma homalonemae, 3~4 parts of fructus viticis, 6~8 parts of notopterygium root, 3~5 parts of asarum, 3~4 parts of the Radix Astragali, 4~6 parts of smilax, earthworm 8 ~9 parts, 8~9 parts of the root of bidentate achyranthes, 5~6 parts of the bark of eucommia.
Preferably, it is made up of following raw material by weight:It is 12 parts of Ramulus Taxilli, 8 parts of the red sage root, 5 parts of the bighead atractylodes rhizome, 6 parts of rhizoma homalonemae, climing 3 parts of Jing Zi, 6 parts of notopterygium root, 3 parts of asarum, 3 parts of the Radix Astragali, 4 parts of smilax, 7 parts of earthworm, 7 parts of the root of bidentate achyranthes, 5 parts of the bark of eucommia.
Preferably, it is made up of following raw material by weight:14 parts of Ramulus Taxilli, 10 parts of the red sage root, 8 parts of the bighead atractylodes rhizome, 10 parts of rhizoma homalonemae, 5 parts of fructus viticis, 8 parts of notopterygium root, 5 parts of asarum, 5 parts of the Radix Astragali, 6 parts of smilax, 9 parts of earthworm, 9 parts of the root of bidentate achyranthes, 6 parts of the bark of eucommia.
According to《Compendium of Materia Medica》、《Chinese pharmacology》With《Roster of Medicine Plant in Guangxi》Recorded Deng Chinese medicine books, main original of the invention Material has following effect.
Ramulus Taxilli:With except rheumatism, detumescence, heat-clearing, eliminating the phlegm is pleasant, the effect of cough-relieving.
The red sage root:It is inducing meastruation to relieve menalgia with promoting blood circulation, relieving restlessness that clears away heart-fire, the effect of cool blood to disappear carbuncle.
The bighead atractylodes rhizome:With strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, the effect of hidroschesis.
Rhizoma homalonemae:With wind-damp dispelling, stimulate the circulation of the blood and cause the muscles and joints to relax, relieve pain, the effect of detumescence.
Fructus viticis:With dispelling wind and heat from the body, head clearing, at dehumidifying the effect of joint.
Notopterygium root:With scattered exterior cold, wind-damp dispelling, sharp joint, the effect of analgesic.
Asarum:With relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping is sensible, the effect of Wenfei of drink.
The Radix Astragali:With tonifying middle-Jiao and Qi, Gu the effect of table arrest sweating, inducing diuresis for removing edema, torr sore apocenosis.
Smilax:With removing toxic substances, dehumidifying, the effect of sharp joint.
Earthworm:It is promoting blood circulation and removing blood stasis with clearing and activating the channels and collaterals, the effect of heat-clearing is calmed the frightened.
The root of bidentate achyranthes:With dispelling stasis of blood and stimulating the menstrual flow, filling liver kidney, strengthening the bones and muscles, inducing diuresis for treating strangurtia, the effect of ensurining proper downward flow of the blood.
The bark of eucommia:The bark of eucommia has filling liver kidney, the effect of control spinal column ache, foot and knee flaccidity, dribbling urination.
The beneficial effects of the invention are as follows:The medicine of present invention treatment rheumatism, from natural plants as raw material, using each The comprehensive function treatment rheumatism of raw material components, toxic and side effect is small and cheap, with kidney and spleen invigorating, clearing heat and detoxicating, relaxing muscles and tendons The effects such as dredging collateral, tonifying kidney and benefiting sperm, the effect treated both principal and secondary aspect of disease can be reached, it is adaptable to the disease such as rheumatism, rheumatoid arthritis Treatment.
Specific embodiment
Embodiment one
A kind of medicine for treating rheumatism, is made up of following raw material by weight:12 parts of Ramulus Taxilli, 8 parts of the red sage root, 5 parts of the bighead atractylodes rhizome, thousand Years strong 6 parts, 3 parts of fructus viticis, 6 parts of notopterygium root, 3 parts of asarum, 3 parts of the Radix Astragali, 4 parts of smilax, 7 parts of earthworm, 7 parts of the root of bidentate achyranthes, 5 parts of the bark of eucommia. Its preparation method is comprised the following steps:
1. matched by above-mentioned raw materials, be ground into 60~100 targeted fine powders;
2. after adding the clear water and fine powder of 6000~8000mL to be sufficiently stirred for, after heating is decocted 2~3 hours, filtering;
3. the filtrate that will be filtrated to get is encapsulated with bottle, and every bottle of capacity is 60mL.
Instructions of taking:Morning, noon and afternoon respectively take a bottle, every minor tick more than 4 hours, 10 days courses for the treatment of.
Embodiment two
A kind of medicine for treating rheumatism, is made up of following raw material by weight:14 parts of Ramulus Taxilli, 10 parts of the red sage root, 8 parts of the bighead atractylodes rhizome, 10 parts of rhizoma homalonemae, 5 parts of fructus viticis, 8 parts of notopterygium root, 5 parts of asarum, 5 parts of the Radix Astragali, 6 parts of smilax, 9 parts of earthworm, 9 parts of the root of bidentate achyranthes, the bark of eucommia 6 Part.Its preparation method is comprised the following steps:
1. matched by above-mentioned raw materials, be ground into 60~100 targeted fine powders;
2. after adding the clear water and fine powder of 6000~8000mL to be sufficiently stirred for, after heating is decocted 2~3 hours, filtering;
3. the filtrate that will be filtrated to get is encapsulated with bottle, and every bottle of capacity is 60mL.
Instructions of taking:Morning, noon and afternoon respectively take a bottle, every minor tick more than 4 hours, 10 days courses for the treatment of.
80 rheumatisants of selection, male 40, female 40, average age are 51 years old.Diagnostic criteria:With reference to " Americanism The standard that diseases caused by dampness association " formulates, i.e.,:According to medical history, physical diagnosis and radiological examination result:The pain of the knee joint, be provided simultaneously with 3 in lower 6 conditions determine clinical diagnosis, and 1. radiology shows spur and formed;2. it is stiff from morning to be less than 30 minutes;③ There is bone sound during joint motion;4. knee joint bone increase;5. there is bone tenderness;6. heated up without obvious synovial membrane.
Efficacy determination:It is effective:Gonalgia symptom disappears, and the morning stiffness time shortens or without morning stiffness, and physico-chemical examination is normal.It is good Turn:Gonalgia symptom mitigation, physico-chemical examination makes moderate progress.It is invalid:, without mitigation, physico-chemical examination is without change for gonalgia.
Through clinical statisticses, symptom substantially mitigates after taking a course for the treatment of, and the gonalgia symptom of patient disappears, during morning stiffness Between shorten or without morning stiffness, physico-chemical examination is normal, therefore all meets effective criterion of therapeutical effect, and is not seen during whole treatment Observe obvious adverse reaction.
Counted according to clinical observation, patient's symptom after 3~4 courses for the treatment of greatly slows down or disappears, and effective 62 people accounts for 77.5%; Take a turn for the better 15 people, accounts for 18.75%;Invalid 3 people, accounts for 3.75%;Total effective rate a height of 96.25%, shows the medicine of present invention treatment rheumatism Thing has obvious curative effects to rheumatism.
Typical case:
Case 1:, 49 years old, there is left gonalgia and continues 6 years as long as in Chen, and arthralgia is aggravated to the cold, visits multiple hospitals Attempt treatment to have no resolution, after 3 courses for the treatment of of medicine of the invention are taken, symptom disappears, and does not occur recurrence so far.
Case 2:Chapter, 54 years old, right gonitis 15 years, it is invalid to seek medical advice in many ways, tries many methods, and effect is exactly not Most people's will.In temperature, 25 degree or so must all pad up, and always be had a dull ache under knee joint, and usually waken up in the evening by pain, in clothes After with 1 course for the treatment of of medicine of the invention, symptom substantially slows down, and after taking 4 courses for the treatment of, recovery from illness has been approached, so far without recurrence.
The above, specific embodiment only of the invention, but protection scope of the present invention is not limited thereto, and it is any The change or simple replacement expected without creative work, should all be included within the scope of the present invention.

Claims (4)

1. a kind of medicine for treating rheumatism, it is characterised in that be made up of following raw material by weight:8~15 parts of Ramulus Taxilli, pellet 8~12 parts of ginseng, 4~8 parts of the bighead atractylodes rhizome, 6~10 parts of rhizoma homalonemae, 2~5 parts of fructus viticis, 5~8 parts of notopterygium root, 3~6 parts of asarum, the Radix Astragali 3~ 5 parts, 3~7 parts of smilax, 7~10 parts of earthworm, 7~10 parts of the root of bidentate achyranthes, 4~7 parts of the bark of eucommia.
2. it is according to claim 1 treatment rheumatism medicine, it is characterised in that be made up of following raw material by weight: It is 12~14 parts of Ramulus Taxilli, 8~10 parts of the red sage root, 5~7 parts of the bighead atractylodes rhizome, 7~9 parts of rhizoma homalonemae, 3~4 parts of fructus viticis, 6~8 parts of notopterygium root, thin Pungent 3~5 parts, 3~4 parts of the Radix Astragali, 4~6 parts of smilax, 8~9 parts of earthworm, 8~9 parts of the root of bidentate achyranthes, 5~6 parts of the bark of eucommia.
3. it is according to claim 1 treatment rheumatism medicine, it is characterised in that be made up of following raw material by weight: 12 parts of Ramulus Taxilli, 8 parts of the red sage root, 5 parts of the bighead atractylodes rhizome, 6 parts of rhizoma homalonemae, 3 parts of fructus viticis, 6 parts of notopterygium root, 3 parts of asarum, 3 parts of the Radix Astragali, smilax 4 parts, 7 parts of earthworm, 7 parts of the root of bidentate achyranthes, 5 parts of the bark of eucommia.
4. it is according to claim 1 treatment rheumatism medicine, it is characterised in that be made up of following raw material by weight: 14 parts of Ramulus Taxilli, 10 parts of the red sage root, 8 parts of the bighead atractylodes rhizome, 10 parts of rhizoma homalonemae, 5 parts of fructus viticis, 8 parts of notopterygium root, 5 parts of asarum, 5 parts of the Radix Astragali, soil Fu 6 parts of Siberian cocklebur, 9 parts of earthworm, 9 parts of the root of bidentate achyranthes, 6 parts of the bark of eucommia.
CN201611203693.XA 2016-12-23 2016-12-23 A kind of medicine for treating rheumatism Withdrawn CN106729209A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112274616A (en) * 2020-11-28 2021-01-29 高娜 A Chinese medicated liquor for the treatment of rheumatic arthralgia

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112274616A (en) * 2020-11-28 2021-01-29 高娜 A Chinese medicated liquor for the treatment of rheumatic arthralgia

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