CN106728446A - It is a kind of to treat medicine of acute tonsillitis and preparation method thereof - Google Patents

It is a kind of to treat medicine of acute tonsillitis and preparation method thereof Download PDF

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CN106728446A
CN106728446A CN201611142322.5A CN201611142322A CN106728446A CN 106728446 A CN106728446 A CN 106728446A CN 201611142322 A CN201611142322 A CN 201611142322A CN 106728446 A CN106728446 A CN 106728446A
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radix
impurity
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root
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董中昌
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
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Abstract

Medicine of acute tonsillitis and preparation method thereof is treated the invention discloses a kind of, it is mainly and is prepared from according to a certain weight ratio by honeysuckle, folium isatidis, ilex pubescens, wintercherry fruit or calyx, balloonflower root, Radix Glycyrrhizae, great burdock achene, radix scrophulariae, moutan bark, peppermint, the root of large-flowered skullcap, Radix Isatidis, Lasiosphaera fenzlii, medicine of the present invention has clearing heat and detoxicating, blood circulation and channel invigorating, detumescence, the function of eliminating the phlegm apocenosis, for treating acute tonsillitis instant effect, good effect, does not recur.

Description

It is a kind of to treat medicine of acute tonsillitis and preparation method thereof
Technical field
Medicine of acute tonsillitis and preparation method thereof is treated the present invention relates to a kind of, belongs to the field of Chinese medicines.
Technical background
Acute tonsillitis is a kind of non-specific acute inflammation of tonsilla palatina, and the green grass or young crops between being more common in 10~30 years old is few Year, and the often acute attack repeatedly on the basis of chronic tonsillitis.The traditional Chinese medical science then thinks to be invaded outside acute tonsillitis and wind-heat, Lung stomach fire fills pass.Because western medicine side effect is big, therefore people deposit to the Chinese medicine of effectively treatment acute tonsillitis In great demand, up to now, it has not been found that on relevant report of the invention.
The content of the invention
The present inventor have found and effectively treat acute finally according to the checking repeatedly of research and the clinical test of theory of traditional Chinese medical science The medicine of tonsillitis, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of effective treatment acute tonsillitis.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention is selection honeysuckle, folium isatidis, ilex pubescens, wintercherry fruit or calyx, balloonflower root, Radix Glycyrrhizae, great burdock achene, radix scrophulariae, male The root bark of tree peony, peppermint, the root of large-flowered skullcap, Radix Isatidis, Lasiosphaera fenzlii, the radix paeoniae rubrathe, dandelion medicine are combined preparation, and these drug regimens are caused respectively Efficacy of drugs produces synergy such that it is able to effectively treat acute tonsillitis.Wherein, from honeysuckle because its nature and flavor It is sweet, tremble with fear, enter lung, stomach, there is heat-clearing, the function of removing toxic substances controls warm disease heating, toxic-heat and blood stasis, large carbuncle, pyogenic infections, scrofula, anal fistula.Choosing With folium isatidis because its is bitter in taste, tremble with fear, enter liver, the heart, stomach have heat-clearing, removing toxic substances, cool blood, the function of hemostasis is controlled warm disease heat and contained Polydipsia, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas is spitted blood, bleeding from five sense organs or subcutaneous tissue, jaundice, Dysentery, larynx numbness, aphtha, swollen ulcer drug.It is mild-natured from ilex pubescens because its nature and flavor slight bitter is sweet, it is nontoxic, have clearing heat and detoxicating, it is living The function that blood is promoted blood circulation, controls anemopyretic cold, dyspnea and cough due to lung-heat, laryngeal edema, tonsillitis, dysentery, coronary heart disease, caused by cerebrovas-cularaccident Hemiplegia, Buerger's disease, erysipelas scalds, central retinitis, uveitis, and skin acute festering type Inflammation.From wintercherry fruit or calyx because its is bitter in taste, tremble with fear, return liver warp has clearing heat and detoxicating, relieving sore-throat, resolving sputum, and the function of diuresis controls pharynx Pain sound is mute, phlegm-heat cough, difficult urination, and pemphigus, eczema are controlled outward.From balloonflower root because its nature and flavor toil, puts down, enter lung, stomach Through, there is out facilitaing lung gas, the function of eliminating the phlegm apocenosis controls exogenous cough, abscess of throat, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery stomachache. From Radix Glycyrrhizae because its property sweet taste, enters spleen, stomach, lung channel, have and processed with middle emergency, moistening lung, removing toxic substances, the function of coordinating the drug actions of a prescription Weakness of the spleen and the stomach with controlling, deficiency of food, loose stool of suffering from abdominal pain, overstrain heating, consumptive lung disease cough, palpitaition shies carbuncle, raw with controlling abscess of throat, digestibility Ulcer, ulcer sores, antidote poison and food poisoning.It is cool from great burdock achene because its nature and flavor is arduous, enter lung, stomach, there is evacuation Wind-heat, facilitaing lung promoting eruption, the function of subdhing swelling and detoxicating controls cough due to wind-heat evil, and abscess of throat, macula is impermeable, and rubella is had an itch, carbuncle sore tumefacting virus. It is salty from radix scrophulariae because its is bitter in taste, it is cool, enter lung, kidney channel, there is enriching yin, fall fire, relieving restlessness, the function of removing toxic substances is controlled pyreticosis and is tired of Yearningly, spot, hectic fever due to yin labor heat are sent out, night sleeps not peaceful, spontaneous sweating, Tianjin hinder constipation, hematemesis and epistaxis, abscess of throat, carbuncle swells, scrofula.From Moutan bark is cool because its nature and flavor is arduous, enters the heart, liver and kidney channel, there is heat-clearing, cool blood, and blood, and the function of dispersing blood stasis controls heat and enters blood Point, spot , Jing Epilepsy is sent out, to tell, be defeated in battle, have blood in stool, hectic fever due to yin labor heat, Amenorrhea , Disorder lumps in the abdomen, large carbuncle flutters damage.From peppermint because its nature and flavor is pungent, It is cool, enter lung, Liver Channel, there is dispelling wind, radiate, ward off dirty, the function of removing toxic substances controls affection of exogenous wind-heat, headache, hot eyes, abscess of throat, food stagnation gas It is swollen, aphtha, toothache, sore scabies, urticaria.From the root of large-flowered skullcap because its taste bitter and cold, enters cardiopulmonary, courage, large intestine channel, have and rush down excess fire, remove Damp and hot, the function of arresting bleeding and miscarriage prevention controls high fever polydipsia, cough with lung heat.From Radix Isatidis because its is bitter in taste, tremble with fear, enter liver, stomach blood Point, there is heat-clearing, to detoxify, the function of cool blood controls influenza, epidemic meningitis, encephalitis, pneumonia, erysipelas, heat toxin hair spot, coma hematemesis, pharynx swelling, Mumps, pinkeye, sore rash.From Lasiosphaera fenzlii because its nature and flavor is pungent, put down.Enter lung channel.Removing heat from the lung and relieving sorethroat, removing toxic substances, hemostasis.Control larynx numbness pharynx Bitterly, cough with aphonia, spits blood, bleeding from five sense organs or subcutaneous tissue, traumatism and bleeding.From the radix paeoniae rubrathe because its is bitter in taste, it is slightly cold, return liver warp has clearing heat and cooling blood, The function of blood stasis removing analgesic, controls epidemic heat syndrome and goes mad, hematemesis and epistaxis, red eye, swell pain, liver-depressed hypochondrium pain, closed dysmenorrhea , Epilepsy lump in the abdomen stomachache, falls and flutters damage Wound, carbuncle swells sore.From dandelion because its nature and flavor bitter sweet, trembles with fear, enter liver, stomach have clearing heat and detoxicating, the work(of diuresis dissipating bind Can, acute mastitis is controlled, adenolymphitis, scrofula, malignant boil carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis is acute Bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infections.
Specific embodiment
The drug dose of instant component is also that inventor summarizes what is drawn by largely groping, and the consumption of each component is following heavy All there is preferable curative effect in the range of amount:
10-20 grams of honeysuckle, 10-20 grams of folium isatidis, 10-20 grams of ilex pubescens, 4-8 grams of wintercherry fruit or calyx, 4-8 grams of balloonflower root, Radix Glycyrrhizae 4-8 Gram, 4-8 grams of great burdock achene, 4-8 grams of radix scrophulariae, 4-8 grams of moutan bark, 4-8 grams of peppermint, 4-8 grams of the root of large-flowered skullcap, 3-7 grams of Radix Isatidis, Lasiosphaera fenzlii 3-7 Gram, 5-15 grams of the radix paeoniae rubrathe, 5-15 grams of dandelion.
Preferably:
15 grams of honeysuckle, 15 grams of folium isatidis, 15 grams of ilex pubescens, 6 grams of wintercherry fruit or calyx, 6 grams of balloonflower root, 6 grams of Radix Glycyrrhizae, 6 grams of great burdock achene, radix scrophulariae 6 grams, 6 grams of moutan bark, 6 grams of peppermint, 6 grams of the root of large-flowered skullcap, 5 grams of Radix Isatidis, 5 grams of Lasiosphaera fenzlii, 10 grams of the radix paeoniae rubrathe, 10 grams of dandelion.
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, honeysuckle:Silt is weeded out, net impurity is picked;
2nd, folium isatidis:Impurity and dead leaf are picked, is cleaned, slightly moistened, segment is dried;
3rd, ilex pubescens:Summer, Qiu Cai, section are dried;
4th, wintercherry fruit or calyx:Remove impurity, carpopodium;
5th, balloonflower root:Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dried;
6th, Radix Glycyrrhizae:Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry;
7th, great burdock achene:Impurity is picked, spare is weeded out;
8th, radix scrophulariae:Net impurity is picked, except removing LU, is cleaned and is run through, cut into slices, dried;
9th, moutan bark:Impurity is picked, core is removed, cleaned, run through, cut into slices, dried;
10th, peppermint:Pick net impurity, remove undesirable root, first by leaf tremble it is lower separately put, stem is then sprayed into clear water, run through rear segment, solarization It is dry, then with leaf and even;
11st, the root of large-flowered skullcap:Impurity is picked, residual stem is removed, slightly leaching is pulled out in infiltrating or putting boiling water with cold water, is cut into slices, and is dried;
12nd, Radix Isatidis:Net impurity is picked, is cleaned, run through, cut into slices, dried;
13rd, Lasiosphaera fenzlii:Remove sclerderm, dice;
14th, the radix paeoniae rubrathe:Crude drug is taken, impurity is removed, size stepping is cleaned, run through, shave, dries, and weeds out chip;
15th, dandelion:Impurity is picked, soil is cleaned, segment is dried.
2nd, prepare
1st, by the honeysuckle of the weight, folium isatidis, ilex pubescens, wintercherry fruit or calyx, balloonflower root, Radix Glycyrrhizae, great burdock achene, radix scrophulariae, moutan bark, thin Lotus, the root of large-flowered skullcap, Radix Isatidis, Lasiosphaera fenzlii, the radix paeoniae rubrathe, dandelion are put into decocting container, are added water 6 times and are measured, and after soaking 30 minutes, intense fire is boiled Boiling, then with being cooked by slow fire 20 minutes, first time decoction liquor is filtered to obtain, first time decoction liquor is poured into container;
2nd, the dregs of a decoction of filtering are added water 4 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor;
3rd, will decoction liquor mixing and stirring twice, be divided into 2 doses and take.
Honeysuckle has clearing heat and detoxicating in prescription, and the function of controlling warm disease heating is monarch drug in a prescription;Ilex pubescens is clearing heat and detoxicating, and promoting blood circulation is logical Arteries and veins;Great burdock achene has a dispelling wind and heat from the body, the function of subdhing swelling and detoxicating, and the two is ministerial drug, and three taste medicines play clearing heat and detoxicating jointly, and promoting blood circulation is logical The effect of warm disease heating is controlled in arteries and veins, detumescence, and treatment acute tonsillitis effect comprehensively, and with clearing heat and detoxicating, blood circulation and channel invigorating, is subsided a swelling Based on can effect a permanent cure, balloonflower root has out facilitaing lung gas, and the function of eliminating the phlegm apocenosis is adjutant, and peppermint wind-dispelling heat-dissipating wards off dirty removing toxic substances to make medicine, with Remaining all medicines are to take stopgap measures.
Medicine of the present invention has clearing heat and detoxicating, blood circulation and channel invigorating, detumescence, the function of eliminating the phlegm apocenosis, for treating acute almond Body is scorching, short treating period, instant effect, non-relapse after healing.
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples include this hair The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention:
Rabbit 30 is taken, male and female dual-purpose, 2.0-2.5kg of body weight is divided to two groups, and every group 15, one of which is tested for overdose Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage Medicine, twice daily, takes medicine continuously 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is without bad Toxic and side effect.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, physical data
Accept acute tonsillitis out-patient totally 27 for medical treatment.
2nd, diagnostic criteria
Classical symptom is chilly, and hyperpyrexia, appetite reduction, malaise, pharyngalgia is had difficulty in breathing, the symptom such as soft palate dyskinesia.
3rd, treatment method
From above-mentioned medicament, taken to patient, each take 1 dose, early daily, evening respectively takes 1 time, be within 4 days a course for the treatment of, continuous clothes With 2 courses for the treatment of.
4th, efficacy assessment standard
It is effective:Acute tonsillitis symptom disappears, and constitution recovers normal, recovery from illness;
Take a turn for the better:Patient's chilly hyperpyrexia, appetite reduction, malaise pharyngalgia, dyspneic phenomenon mitigates, acute tonsil inflammation Shape is clearly better, and constitution is progressively recovered;
It is invalid:Improvement standard person is not reached.
5th, treatment results(See the table below)
In above-mentioned treatment, with drug therapy acute tonsillitis patient 27 of the present invention, as a result effective 23, obvious effective rate is 85.19%, take a turn for the better 3, improvement rate is 11.11%, and invalid 1, total effective rate is 96.3%.

Claims (3)

1. a kind of medicine for treating acute tonsillitis, it is characterised in that:It is made up of the bulk drug in following weight range:
10-20 grams of honeysuckle, 10-20 grams of folium isatidis, 10-20 grams of ilex pubescens, 4-8 grams of wintercherry fruit or calyx, 4-8 grams of balloonflower root, Radix Glycyrrhizae 4-8 Gram, 4-8 grams of great burdock achene, 4-8 grams of radix scrophulariae, 4-8 grams of moutan bark, 4-8 grams of peppermint, 4-8 grams of the root of large-flowered skullcap, 3-7 grams of Radix Isatidis, Lasiosphaera fenzlii 3-7 Gram, 5-15 grams of the radix paeoniae rubrathe, 5-15 grams of dandelion.
2. medicine according to claim 1, wherein the consumption of each bulk drug is:
15 grams of honeysuckle, 15 grams of folium isatidis, 15 grams of ilex pubescens, 6 grams of wintercherry fruit or calyx, 6 grams of balloonflower root, 6 grams of Radix Glycyrrhizae, 6 grams of great burdock achene, radix scrophulariae 6 grams, 6 grams of moutan bark, 6 grams of peppermint, 6 grams of the root of large-flowered skullcap, 5 grams of Radix Isatidis, 5 grams of Lasiosphaera fenzlii, 10 grams of the radix paeoniae rubrathe, 10 grams of dandelion.
3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps:
(One)Get the raw materials ready
(1)Honeysuckle:Silt is weeded out, net impurity is picked;
(2)Folium isatidis:Impurity and dead leaf are picked, is cleaned, slightly moistened, segment is dried;
(3)Ilex pubescens:Summer, Qiu Cai, section are dried;
(4)Wintercherry fruit or calyx:Remove impurity, carpopodium;
(5)Balloonflower root:Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dried;
(6)Radix Glycyrrhizae:Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry;
(7)Great burdock achene:Impurity is picked, spare is weeded out;
(8)Radix scrophulariae:Net impurity is picked, except removing LU, is cleaned and is run through, cut into slices, dried;
(9)Moutan bark:Impurity is picked, core is removed, cleaned, run through, cut into slices, dried;
(10)Peppermint:Pick net impurity, remove undesirable root, first by leaf tremble it is lower separately put, stem is then sprayed into clear water, run through rear segment, solarization It is dry, then with leaf and even;
(11)The root of large-flowered skullcap:Impurity is picked, residual stem is removed, slightly leaching is pulled out in infiltrating or putting boiling water with cold water, is cut into slices, and is dried;
(12)Radix Isatidis:Net impurity is picked, is cleaned, run through, cut into slices, dried;
(13)Lasiosphaera fenzlii:Remove sclerderm, dice;
(14)The radix paeoniae rubrathe:Crude drug is taken, impurity is removed, size stepping is cleaned, run through, shave, dries, and weeds out chip;
(15)Dandelion:Impurity is picked, soil is cleaned, segment is dried;
(Two)Prepare
(1)By the honeysuckle of the weight, folium isatidis, ilex pubescens, wintercherry fruit or calyx, balloonflower root, Radix Glycyrrhizae, great burdock achene, radix scrophulariae, moutan bark, Peppermint, the root of large-flowered skullcap, Radix Isatidis, Lasiosphaera fenzlii, the radix paeoniae rubrathe, dandelion are put into decocting container, are added water 6 times and are measured, and after soaking 30 minutes, intense fire is boiled Boiling, then with being cooked by slow fire 20 minutes, first time decoction liquor is filtered to obtain, first time decoction liquor is poured into container;
(2)The dregs of a decoction of filtering are added water 4 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor;
(3)Decoction liquor mixing and stirring twice is incited somebody to action, is divided into 2 doses and is taken.
CN201611142322.5A 2016-12-13 2016-12-13 It is a kind of to treat medicine of acute tonsillitis and preparation method thereof Withdrawn CN106728446A (en)

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Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
赵东奇: "中医辩证治疗扁桃体炎(转载)", 《HTTPS://WWW.HAODF.COM/ZHUANJIAGUANDIAN/ZHAODONGQI_2527724134.HTM》 *

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