CN106620470A - 一种具有抗疲劳及延缓衰老的中药组合物 - Google Patents

一种具有抗疲劳及延缓衰老的中药组合物 Download PDF

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CN106620470A
CN106620470A CN201611142888.8A CN201611142888A CN106620470A CN 106620470 A CN106620470 A CN 106620470A CN 201611142888 A CN201611142888 A CN 201611142888A CN 106620470 A CN106620470 A CN 106620470A
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赵倬
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Abstract

本发明公开一种具有抗疲劳和延缓衰老的中药组合物。该组合物由羊胎盘、冬虫夏草、桑椹子、淫羊藿、黑芝麻、铁皮石斛、白术、益智仁、海马、百合、葛根等26味原料药组成。本发明组合物按照常规工艺加入常规辅料制成临床接受的胶囊剂、片剂、丸剂、颗粒剂或口服液。本发明药物组合物具有抗疲劳和延缓衰老的功效，效果显著，无副作用。本发明组合物同时不具有促进人体功能恢复的作用。

Description

一种具有抗疲劳及延缓衰老的中药组合物
技术领域
本发明涉及一种中药组合物，特别是涉及一种具有抗疲劳及延缓衰老的中药组合物。
背景技术
疲劳是机体复杂的生理生化变化过程，是指脑力或体力到达一定阶段时必然出现的一种正常的生理现象。它既标志着机体原有工作能力的暂时下降，又可能是机体发展到疾病状态的先兆。从中枢神经系统到骨骼肌细胞再到细胞内的物质代谢过程，中间任何一个环节或者过程综合变化，都可造成疲劳。据WHO调查，全球有35％以上的人处于疲劳状态，中年男性人群疲劳状态达60％。疲劳的出现，可引起运动能力降低、工作效率降低、差错事故增多、战斗力减退。疲劳发生后如果得不到及时恢复，逐渐积累，还会导致“过劳”，出现慢性疲劳综合征(chronic fatigue syndrome，CFS)、“过度训练综合症”等，使机体发生内分泌紊乱、免疫力下降，甚至出现器质性疾病，威胁人类健康。
衰老，也称老化，是指人类在发育成熟以后，随着年龄的增加或时间的增长机体出现组织结构变化、功能减退、适应能力减弱、器官应激能力下降、生活能力逐渐丧失，更易于死亡的过程。自《内经》以来，实践经验早已揭示，从幼年至青年中年，随着五脏的逐渐充盛而机体亦渐强盛。机体衰老是五脏虚衰的结果，五脏所主的每一组织和功能，均无不衰减。现代医学研究也表明影响衰老的因素极为复杂。当前医学衰老机理及其中医药延缓衰老研究认为，人是一个有机的整体，五脏则是这一有机整体的主持中心。衰老作为复杂生命现象的一种变化，是多因素综合作用的结果，是个体的衰老是各脏器衰老的总和。从器官的整体水平和分子细胞的研究发现，衰老与遗传基因、自由基、内分泌功能失调，免疫功能紊乱等因素有关。研究发现，人体内代谢产生的大量氧化物自由基，破坏细胞功能，导致人体的心脏器官老化。内分泌功能失调，首当其冲受影响的也是肌体内脏器官的功能衰退，随着身体的损耗积累，导致老化。
发明内容
本发明目的在于提供一种具有抗疲劳及延缓衰老的中药组合物。
本发明是通过如下技术方案实现的：
本发明组合物的原料药组成为：
本发明组合物的原料药组成优选为：
本发明组合物的原料药组成优选为：
本发明组合物的原料药组成优选为：
本发明组合物可按照常规工艺加入常规辅料制成临床接受的胶囊剂、片剂、丸剂、颗粒剂或口服液。
本发明药物组合物具有抗疲劳和延缓衰老的功效，效果显著，无副作用。本发明组合物同时不具有促进人体功能恢复的作用。
下面实验例用于进一步说明本发明，但不限于本发明。
实验例一：动物药效学试验(抗疲劳)
1.本发明实验药物：按照实施例1方法制备，将本发明中药胶囊内容物用花生油配制成混悬液，本发明中药软胶囊内容物与花生油的比例为1∶3。
采用小鼠游泳实验进一步阐述本发明。
2、雄性昆明种小鼠50只，体重17-22g/只，随机分为5组，每组10只，每天灌胃1次，持续2周，空白组灌胃等容量的蒸馏水，对照组给予等容积的0.5％CMC-Na溶液，给药大、中、小剂量组给予本发明实验药物。
3、小鼠体重影响
表1 小鼠体重影响
由表1可见，空白组、模型组与本发明给药小、中、大剂量组在试验中期、末期及增重上均无显著性差异。
4、小鼠力竭性游泳时间比较
将小鼠于游泳装置中开始3％体质量的负重游泳，水温30℃，记录力歇性游泳时间。
表2 各组小鼠力竭性游泳时间比较(min，x±SD)
由表2可见，负重游泳试验中本发明给药小、中、大剂量组动物的游泳时间均长于空白组和模型组，其中本发明给药小、中、大剂量组与空白组和模型组相比，差异有显著性(P＜0.05)。
实验例二：动物药效学试验(延缓衰老)
1.本发明实验药物：按照实施例1方法制备，将本发明中药胶囊内容物用花生油配制成混悬液，本发明中药软胶囊内容物与花生油的比例为1∶3。
2.选昆明种小鼠50只，体重17-22g/只，随机分为5组，每组10只。
3.分组、给药及处理
50只小鼠随机分为空白组、模型组、本发明小剂量组、本发明中剂量组、本发明大剂量组，每组10只。
空白组：每天皮下注射生理盐水，剂量相当于其它给药组D-Gal给药量，同时灌服温开水。
模型组：按文献方法制备衰老小鼠模型。注射用水配制10％D-Gal，小鼠颈背部皮下注射10mL/kg，每天1次，连续6周。
本发明小剂量组：每天按生药量与小鼠体重1g/kg灌服本发明实验药物；
本发明中剂量组：每天按生药量与小鼠体重2g/kg灌服本发明实验药物；
本发明大剂量组：每天按生药量与小鼠体重3g/kg灌服本发明实验药物；
每组小鼠连续给药6周后，处死动物，取材。
4.指标测定
取肝脏标本，用冷生理盐水漂洗，拭干称重，加入9倍体积预冷的匀浆介质(pH7.4，0.01mol/L Tris-HCl，0.0001mol/L EDTA-2Na，0.01mol/L蔗糖，0.8％氯化钠溶液)，冰浴电动匀浆，将肝组织匀浆3000r/min低温离心10min，取上清冻存待测。按上述方法制备肝匀浆，取10％肝组织匀浆2000r/min低温离心10min，弃沉淀，取上清液10000r/min在高速冷冻离心机中离心15min，沉淀物即为线粒体，将线粒体悬浮于介质中，供指标测定。按试剂盒说明测定肝组织Ca2+-ATP酶活性，肝线粒体丙二醛(MDA)含量。按文献测定磷脂酶A2(PLA2)活性，肝线粒体膜流动性(n)。
5.统计学分析
实验数据以均数±标准差表示，应用SPSS15.0统计学软件进行统计学分析。
6.不同药物对至衰小鼠肝脏Ca2+-ATP酶活性、MDA、PLA2活性、膜流动性(n)的影响
表3 不同药物对至衰小鼠肝脏Ca2+-ATP酶活性、MDA、PLA2活性、膜流动性(n)的影响
注：模型组与空白组比较，#：P＜0.01；给药组与模型组比较，*：P＜0.05；**：P＜0.01。
7.结果
模型组与空白组比较，Ca2+-ATP酶活性、肝线粒体膜流动性下降，肝线粒体MDA含量、PLA2活性升高，表明造模成功。本发明给药小剂量组、给药中剂量组、给药大剂量组与模型组比较，Ca2+-ATP活性均有明显升高，MDA含量、PLA2活性明显降低，表明本发明给药小剂量组、给药中剂量组、给药大剂量组能够提高衰老模型小鼠肝脏Ca2+-ATP酶活性、肝线粒体膜流动性，降低肝线粒体MDA含量、PLA2活性(P＜0.05)见表3，证明本发明小、中、大剂量组均具有抗衰老作用。
下述实施例均能实现上述实验例的效果。
具体实施方式
实施例1 胶囊剂
将上述药物按照常规工艺加入常规辅料制成胶囊剂。0.4g/粒，一日二次，每次2粒。
实施例2 片剂
上述药物按照常规工艺加入常规辅料制成片剂。0.2g/片，一日二次，每次2片。
实施例3 丸剂
上述药物按照常规工艺加入常规辅料制成蜜丸。每日二次，每次1粒。
实施例4 颗粒剂
上述药物按照常规工艺加入常规辅料制成颗粒剂。每日二次，每次1袋。
实施例5 口服液
上述药物按照常规工艺加入常规辅料制成口服液。每日二次，每次1支。

Claims (6)

1.一种具有抗疲劳及延缓衰老的中药组合物，其特征在于，该组合物的原料药组成为：
2.如权利要求1所述的组合物，其特征在于该组合物的原料药组成为：
3.如权利要求1所述的组合物，其特征在于该组合物的原料药组成为：
4.如权利要求1所述的组合物，其特征在于该组合物的原料药组成为：
5.如权利要求1-4之一所述的组合物，其特征在于该组合物按照常规工艺加入常规辅料制成临床接受的胶囊剂、片剂、丸剂、颗粒剂或口服液。
6.如权利要求1-4之一所述的组合物在制备治疗抗疲劳及延缓衰老的药物中的应用。
CN201611142888.8A 2016-12-06 2016-12-06 一种具有抗疲劳及延缓衰老的中药组合物 Pending CN106620470A (zh)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107997094A (zh) * 2017-12-30 2018-05-08 赵赛 一种女士滋补养生汤
CN108617980A (zh) * 2018-05-10 2018-10-09 湖南师范大学 一种羊胎膏、其制备方法及用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104940725A (zh) * 2015-06-29 2015-09-30 广西健宝石斛有限责任公司 一种养血美容的铁皮石斛中药组合物及其制剂

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104940725A (zh) * 2015-06-29 2015-09-30 广西健宝石斛有限责任公司 一种养血美容的铁皮石斛中药组合物及其制剂

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107997094A (zh) * 2017-12-30 2018-05-08 赵赛 一种女士滋补养生汤
CN108617980A (zh) * 2018-05-10 2018-10-09 湖南师范大学 一种羊胎膏、其制备方法及用途

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