CN106492182A - A kind of pharmaceutical formulation for treating bronchitis and its production technology - Google Patents
A kind of pharmaceutical formulation for treating bronchitis and its production technology Download PDFInfo
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- CN106492182A CN106492182A CN201611226011.7A CN201611226011A CN106492182A CN 106492182 A CN106492182 A CN 106492182A CN 201611226011 A CN201611226011 A CN 201611226011A CN 106492182 A CN106492182 A CN 106492182A
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Abstract
The present invention relates to a kind of pharmaceutical formulation for treating bronchitis and its production technology, which is made up of following parts by weight of component：15 20 parts of Bulbus Fritillariae Thunbergii, 10 15 parts of the Radix Astragali, 10 15 parts of Poria, 10 15 parts of Cortex Lycii, 10 15 parts of Folium Mori, 8 12 parts of Radix Glehniae, 8 12 parts of Radix Asparagi, 8 10 parts of Fructus Schisandrae Chinensis, 8 10 parts of Radix Ginseng, 8 10 parts of the Rhizoma Pinelliae, 68 parts of Radix Panacis Quinquefolii, 5 10 parts of Fructus Jujubae, 79 parts of Folium Eriobotryae, 68 parts of Bulbus Lilii, 68 parts of Pericarpium Citri Reticulatae, 47 parts of Fructus Perillae, 46 parts of Fructus Psoraleae, 46 parts of Semen Juglandis, 46 parts of Herba Asari, 46 parts of Radix Aconiti Lateralis Preparata, 35 parts of Placenta Hominiss, 35 parts of Rhizoma Zingiberiss, 13 parts of 35 parts of Semen Lepidii (Semen Descurainiae) and Rhizoma Polygonati, tonifying the lung spleen invigorating played altogether by all medicines, benefiting QI for strengthening the superficies, the effect of helping inspiration to relieve asthma, according to clinical verification, the effective percentage of we is 100%.
Description
Technical field
The present invention relates to a kind of pharmaceutical formulation for treating bronchitis and its production technology.
Background technology
Chronic bronchitiss, refer to the chronic nonspecific inflammatory change of trachea-bronchial epithelial cell mucosa and its surrounding tissue.Always
Nian Renzhong sickness rate is very high, accounts for the 10%～15% of old people's sum.Primary disease mainly with atmospheric pollution, smoking, infection, allergy and
Climate change etc. is relevant, but many factors also imperfectly understand so far but modern medicine the preventing and treating of primary disease is still lacked more satisfactory
Method.
Repeatedly invasion and attack of the generation of primary disease with development often with exopathogen, lung, spleen, three dirty functional disorder of kidney are closely related.Acute
Stage of attack, mostly because of insufficiency of lung-QI, weakened defensive QI exopathogen is invaded, so that cough recurrent exerbation；Or sent out because of chronic cough endlessly, repeatedly
Make, or body void with age, lung spleen deficiency of kidney-QI, water Tianjin not cloth stops in phlegm retention, checks in lung, cause long-term cough with asthma, or because ingest,
The factor such as drink is injured in lung, and then forms primary disease.Pathological changes do not recover for a long time, then lung spleen is undermined in kidney, therefore the normal companion of the person of being in a bad way
There is asthma to be unable to prostration, dynamic then more so grade failure of the kidney in receiving QI time.
Currently for having reported in the treatment by Chinese herbs prior art of chronic bronchitiss,
CN201610779751.7 discloses a kind of Chinese medicine decoction for treating chronic bronchitiss, and the weight portion of its constitutive material is：Gold
14-18 gram of Flos Lonicerae, 4-7 gram of Folium Perillae, 8-12 gram of Radix Adenophorae (Radix Glehniae), 10-14 gram of Radix Platycodoniss, 10-15 gram of Fructus Trichosanthis, 9-11 gram of Bulbus Fritillariae Cirrhosae, Rhizoma Cynanchi Stauntonii 8-
10 grams, 10-15 gram of Flos Inulae, 8-12 gram of Semen Sinapis Albae, 5-10 gram of Rhizoma Pinelliae Preparata, 13-19 gram of Poria, 8-12 gram of Radix Glycyrrhizae, Radix Angelicae Sinensis 8-
2-4 gram of 12 grams, 5-10 gram of Pericarpium Citri Reticulatae, 4-7 gram of Chinese Magnoliavine, 10-20 gram of Cortex Mori, water Mao Huake 1-3 gram and water wolf beanstalk.Application No.
The a kind of of CN201610745612.2 treats effect of chronic bronchitiss and preparation method thereof, by following weight portion into packet
Into：12 grams of Cortex Magnoliae Officinalis, 10 grams of Radix Polygalae, 8 grams of Bombyx Batryticatus, 15 grams of Radix Adenophorae (Radix Glehniae), 3 grams of Medulla Tetrapanacis, 6 grams of Folium Nelumbinis, 13 grams of Dens Draconiss, 7 grams of Radix Curcumae, Fructus Schisandrae Chinensis
5 grams, 2 grams of Fructus Evodiae, 22 grams of Exocarpium Benincasae, 3 grams of Lignum Aquilariae Resinatum, 4 grams of Gecko, 9 grams of Radix Glycyrrhizae.But current treatment by Chinese herbs effect can not
Make one satisfied, the easy recurrent exerbation of western medicine.
In view of this invention one kind is needed to treat bronchial pharmaceutical formulation and its production technology.
Content of the invention
The technical problem to be solved is to provide a kind of pharmaceutical formulation for treating bronchitis, and provides which simultaneously
Production technology.
For solving the above problems, the technical solution used in the present invention is：
One aspect of the present invention provides a kind of pharmaceutical formulation for treating bronchitis, and its key technology point is, which is by weighing as follows
Amount part group is grouped into：Bulbus Fritillariae Thunbergii 15-20 parts, Radix Astragali 10-15 parts, Poria 10-15 parts, Cortex Lycii 10-15 parts, Folium Mori 10-15 parts,
Radix Glehniae 8-12 parts, Radix Asparagi 8-12 parts, Fructus Schisandrae Chinensis 8-10 parts, Radix Ginseng 8-10 parts, Rhizoma Pinelliae 8-10 parts, Radix Panacis Quinquefolii 6-8 parts, Fructus Jujubae 5-
10 parts, Folium Eriobotryae 7-9 parts, Bulbus Lilii 6-8 parts, Pericarpium Citri Reticulatae 6-8 parts, Fructus Perillae 4-7 part, Fructus Psoraleae 4-6 parts, Semen Juglandis 4-6 parts, Herba Asari 4-
6 parts, Radix Aconiti Lateralis Preparata 4-6 parts, Placenta Hominiss 3-5 parts, Rhizoma Zingiberiss 3-5 parts, Semen Lepidii (Semen Descurainiae) 3-5 parts and Rhizoma Polygonati 1-3 parts.
Used as further improvement of the invention, the above-mentioned pharmaceutical formulation for treating bronchitis, which is by following weight portion group
It is grouped into：18 parts of Bulbus Fritillariae Thunbergii, 13 parts of the Radix Astragali, 13 parts of Poria, 12 parts of Cortex Lycii, 12 parts of Folium Mori, 10 parts of Radix Glehniae, 10 parts of Radix Asparagi,
9 parts of Fructus Schisandrae Chinensis, 9 parts of Radix Ginseng, 9 parts of the Rhizoma Pinelliae, 7 parts of Radix Panacis Quinquefolii, 7 parts of Fructus Jujubae, 8 parts of Folium Eriobotryae, 7 parts of Bulbus Lilii, 7 parts of Pericarpium Citri Reticulatae, Fructus Perillae 6
2 parts of part, 5 parts of Fructus Psoraleae, 5 parts of Semen Juglandis, 5 parts of Herba Asari, 5 parts of Radix Aconiti Lateralis Preparata, 4 parts of Placenta Hominiss, 4 parts of Rhizoma Zingiberiss, 4 parts of Semen Lepidii (Semen Descurainiae) and Rhizoma Polygonati.
Another aspect of the present invention provides a kind of production technology of the pharmaceutical formulation of above-mentioned treatment bronchitis, its crucial skill
Art point is, comprises the steps：
Medical material is weighed by formula, clean for medical material, chopping post-drying is then less than to water content by the medical material mix homogeneously for weighing
1%, then it is ground, is sieved using the sieve of 80 mesh, is added to the water immersion 20-30 minutes, carries out first time decoction,
At a simmer front employing intense fire is decocted, and with 45-60 minutes are cooked by slow fire after boiling, is leached medicinal liquid, is obtained filtering residue, and second decocts, and adds water, greatly
After fiery water boiling, 20-30 minutes are cooked by slow fire, medicinal liquid is leached, finite concentration is concentrated into, lyophilization obtains powder, encapsulated.
Further, 8-10 times for medical material gross mass of the amount of addition water when described first time decocts, described second
4-5 times for medical material gross mass of the amount added when secondary pan-fried.
In the formula of the present invention：
Bulbus Fritillariae Thunbergii：Nature and flavor are bitter, tremble with fear.Return through return lung, heart channel.Indication heat clearing away eliminating stagnation, preventing phlegm from forming and stopping coughing, for wind-heat invading the lung, expectorant
Fire cough, lung abscess, acute mastitis, scrofula, sore.
The Radix Astragali：Taste：Sweet, temperature.Return through return lung, spleen channel.Indication：Invigorating QI to consolidate the body surface resistance, diuretic and maintain drug, evacuation of pus, sore are given birth to
Flesh.For treatment deficiency of vital energy weak, anorexia and loose stool, sinking of QI of middle-JIAO, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle are difficult
Burst, bursts for a long time and does not holds back, flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes；Chronic nephritis proteinuria, diabetes.
Poria：Nature and flavor are sweet, light, put down.Return through GUIXIN, lung, spleen, kidney channel.Indication promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For
Edema oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool are had loose bowels, irritability, insomnia of palpitating with fear.
Cortex Lycii：Nature and flavor are sweet, tremble with fear.Return through return lung, liver and kidney channel.Indication removing heat from blood is except steaming, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever,
Hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis, Heat Diabetes.
Folium Mori：Nature and flavor are sweet, bitter, tremble with fear.Return through return lung, Liver Channel.Indication dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.With
In anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion are dim-sighted.
Radix Glehniae：Nature and flavor are sweet, slight bitter, are slightly cold.Return through attaches to the lung and stomach meridians.Indication nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid.For
Lung-heat type cough, chronic cough expectorant blood, calentura injury thirst.
Radix Asparagi：Nature and flavor are sweet, bitter, tremble with fear.Return through return lung, kidney channel.Indication nourishing YIN to relieve dryness, lung heat clearing are promoted the production of body fluid.Dry for the dryness of the lung
Cough, pertussis expectorant is sticked, dry throat and mouth, dry constipation of intestines.
Fructus Schisandrae Chinensis：Nature and flavor are sour, sweet, temperature.Return through return lung, the heart, kidney channel.Indication convergence is astringent or styptic treatment for spontaneous sweating, and supplementing QI for promoting the production of body fluid, the kidney invigorating are peaceful
The heart.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, injury thirst, deficient pulse of losing heart, interior-heat disappear
Yearningly, palpitation and insomnia.
Radix Ginseng：Nature and flavor are sweet, slight bitter, put down.Return through returns spleen, lung, heart channel.Indication strongly invigorating primordial QI, veins takes off admittedly, spleen reinforcing benefit
Lung, promotes the production of body fluid, and calms the nerves.For weak body and prostration, cold weak pulse of limb, spleen eating less, the deficiency of the lung are breathed with cough, injury thirst, Heat Diabetes, and prolonged illness is empty
Thin, insomnia of palpitating with fear, sexual impotence cold womb；Heart failure, cardiogenic shock.
The Rhizoma Pinelliae：Nature and flavor are pungent, temperature；Poisonous.Return through returns spleen, stomach, lung meridian.Indication drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the painful abdominal mass that disappears dissipate
Knot.For abundant expectoration cough and asthma, phlegm retention anti-dazzle nervous, dizziness due to wind-phlegm, phlegm and headache, vomiting gastric disorder causing nausea, chest gastral cavity ruffian, globus hystericuss；Life external treatment
Carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for stopping nausea and vomiting by lowering the adverse flow of QI.
Radix Panacis Quinquefolii：Nature and flavor are sweet, slight bitter, cool.Return through GUIXIN, lung, kidney channel.Indication boosting qi and nourishing yin, clearing away heat and promoting production of body fluid.For
Deficiency of vital energy yin deficiency, interior-heat, cough with asthma expectorant blood, deficiency-heat is tired of tired, quenches one's thirst, dryness of the mouth and throat.
Fructus Jujubae：Nature and flavor are sweet, temperature.Return through returns spleen, stomach.Indication fruit（Fructus Jujubae）：Invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.For
Spleen eating less, weak loose stool, woman hysteria.
Folium Eriobotryae：Nature and flavor are bitter, are slightly cold.Return through attaches to the lung and stomach meridians.Indication clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.Cough for lung-heat
Cough, QI rising in reverse order dyspnea with rapid respiration, gastric heat vomiting, dysphoria and thirsty.
Bulbus Lilii：Nature and flavor are sweet, tremble with fear.Return through GUIXIN, lung meridian.Indication nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.For yin chronic cough,
Sputum mixed with blood, dysphoria palpitates with fear, insomnia and dreamful sleep, absentminded.
Pericarpium Citri Reticulatae：Nature and flavor are bitter, pungent, temperature.Return through return lung, spleen channel.Indication regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Swollen for breast gastral cavity
Full, lack of appetite and vomiting, cough with copious phlegm.
Fructus Perillae：Nature and flavor are pungent, temperature.Return through return lung is passed through.Indication sending down the abnormal ascending QI expectorant, relievings asthma, intestine moistening.For phlegm stops up the circulation of vital energy in the wrong direction, cough
Cough asthma, dry constipation of intestines.
Fructus Psoraleae：Nature and flavor are pungent, bitter, temperature.Return through returns kidney, spleen channel.Indication warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI, antidiarrheal.For sexual impotence
Seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, kidney deficiency are breathed heavily, Diarrhoea；External curing vitiligo, alopecia areata.
Semen Juglandis：Nature and flavor are sweet, temperature.Return through returns kidney, lung, large intestine channel.Indication the kidney invigorating, warming the lung, intestine moistening.For waist and knee acid
Soft, impotence and seminal emission, deficiency and coldness are breathed heavily and are coughed, constipation.
Herba Asari：Nature and flavor are pungent, temperature.Return through GUIXIN, lung, kidney channel.Indication expelling wind and cold, sensible pain relieving, warming the lung to resolve fluid-retention.With
In anemofrigid cold, headache, toothache, nasal sinusitis of having a stuffy nose, rheumatic arthralgia, phlegm and retained fluid is breathed with cough.
Radix Aconiti Lateralis Preparata：Nature and flavor are pungent, sweet, big heat；Poisonous.Return through GUIXIN, kidney, spleen channel.Indication recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang,
By wind-cold damp pathogen.Collapse for YANG-depletion, cold weak pulse of limb, sexual impotence, cold womb, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, cold sensation of the genitalia oedema, outside yang deficiency
Sense, arthralgia due to cold-dampnes.
Placenta Hominiss：Nature and flavor are sweet, salty, temperature.Return through GUIXIN, lung, kidney channel.Indication the kidney warming mends essence, benefiting QI and nourishing blood.For void
Labor weakness and emaciation, hectic fever due to YIN-deficiency night sweat, cough and asthma, lack of appetite shortness of breath, impotence and seminal emission, infertile hypogalactia.
Rhizoma Zingiberiss：Nature and flavor are pungent, heat.Indication warming middle-JIAO is by cold, Back to Yang Tongmai.Trusted subordinate's crymodynia is controlled, is vomited and diarrhoea, cold weak pulse of limb is trembled with fear
Secondary breath with cough, anemofrigid-damp arthralgia, yang deficiency is told, is defeated in battle, hematochezia.
Semen Lepidii (Semen Descurainiae)：Nature and flavor are pungent, bitter, Great Cold.Return through return lung, bladder warp.Indication eliminating pathogen from the lung for relieving asthma, line water detumescence.For
Sputum stop up lung, dyspnea and cough with excessive sputum, fullness and distention in the chest and hypochondrium, must not prostration, chest and abdomen oedema, dysuria；Pulmonary heart disease edema.
Rhizoma Polygonati：Nature and flavor are sweet, put down.Return through returns spleen, lung, kidney channel.Indication boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For
Weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, Heat Diabetes.
It is using the beneficial effect produced by above-mentioned technical proposal：
The present invention takes into full account compatibility relationship between medicine, scientific composition, Radix Ginseng, the West according to Chinese medical discrimination and therapy theory
Ginseng, the Radix Astragali and Fructus Jujubae invigorating the spleen to benefit the lung, benefit defend consolidating superficial resistance can the spleen reinforcing deficiency of the lung；Fructus Psoraleae, Semen Juglandis and Placenta Hominiss helping inspiration to relieve asthma, warm spleen temperature
Lung can be used for deficiency of spleen-YANG and kidneyYANG；Radix Glehniae, Bulbus Lilii, Radix Asparagi and Rhizoma Polygonati nourishing the lung to arrest cough, for the cough caused by dryness-heat of deficiency of lung-YIN；Fructus Schisandrae Chinensis are held back
Lung nourishing kidney, for chronic cough dyspnea due to deficiency；Herba Asari warming the lung to resolve fluid-retention；Rhizoma Zingiberiss and Radix Aconiti Lateralis Preparata warming spleen and stomach for dispelling cold；Cortex Lycii lung heat clearing pathogenic fire reducing；Folium Mori lung heat clearing is moistened
Dry；Pericarpium Citri Reticulatae, the Rhizoma Pinelliae, Poria and Fructus Perillae dissipating phlegm and keeping the adverse QI downwards are relievingd asthma, and Bulbus Fritillariae Thunbergii, Folium Eriobotryae and Semen Lepidii (Semen Descurainiae) lung moistening sending down the abnormal ascending QI, all medicines play benefit altogether
The effect of lung spleen invigorating, benefiting QI for strengthening the superficies, helping inspiration to relieve asthma, according to clinical verification, the effective percentage of we is 100%.
Specific embodiment
For making the object, technical solutions and advantages of the present invention clearer, invention is carried out with reference to specific embodiment
Clear, complete description.
Embodiment 1
The pharmaceutical formulation for the treatment of bronchitis, which is made up of following parts by weight of component：Bulbus Fritillariae Thunbergii 18g, Radix Astragali 13g, Poria 13g,
Cortex Lycii 12g, Folium Mori 12g, Radix Glehniae 10g, Radix Asparagi 10g, Fructus Schisandrae Chinensis 9g, Radix Ginseng 9g, Rhizoma Pinelliae 9g, Radix Panacis Quinquefolii 7g, Fructus Jujubae 7g, Pi
Rake leaf 8g, Bulbus Lilii 7g, Pericarpium Citri Reticulatae 7g, Fructus Perillae 6g, Fructus Psoraleae 5g, Semen Juglandis 5g, Herba Asari 5g, Radix Aconiti Lateralis Preparata 5g, Placenta Hominiss 4g, Rhizoma Zingiberiss 4g,
Semen Lepidii (Semen Descurainiae) 4g and Rhizoma Polygonati 2g.
Preparation method comprises the steps：
Medical material is weighed by formula, clean for medical material, chopping post-drying is then less than to water content by the medical material mix homogeneously for weighing
1%, then it is ground, is sieved using the sieve of 80 mesh, adds in 9 times of water of medical material gross weight and soak 25 minutes, carry out
Decoct for the first time, at a simmer front employing intense fire is decocted, and with being cooked by slow fire 50 minutes after boiling, is leached medicinal liquid, is obtained filtering residue, second decocts
Boil, add 4.5 times of medical material gross weight, after the boiling of big fire water, be cooked by slow fire 25 minutes, leach medicinal liquid, be concentrated into finite concentration, freeze
Dry, obtain powder, 5g mono- is encapsulated.
Embodiment 2
The pharmaceutical formulation for the treatment of bronchitis, which is made up of following components by weight percent：Bulbus Fritillariae Thunbergii 20g, Radix Astragali 15g, Poria 10g,
Cortex Lycii 15g, Folium Mori 10g, Radix Glehniae 12g, Radix Asparagi 8g, Fructus Schisandrae Chinensis 10g, Radix Ginseng 8g, Rhizoma Pinelliae 10g, Radix Panacis Quinquefolii 6g, Fructus Jujubae 10g, Pi
Rake leaf 7g, Bulbus Lilii 8g, Pericarpium Citri Reticulatae 6g, Fructus Perillae 7g, Fructus Psoraleae 4g, Semen Juglandis 6g, Herba Asari 4g, Radix Aconiti Lateralis Preparata 6g, Placenta Hominiss 3g, Rhizoma Zingiberiss 5g,
Semen Lepidii (Semen Descurainiae) 3g and Rhizoma Polygonati 3g.
Preparation method comprises the steps：
Medical material is weighed by formula, clean for medical material, chopping post-drying is then less than to water content by the medical material mix homogeneously for weighing
1%, then it is ground, is sieved using the sieve of 80 mesh, adds in 9 times of water of medical material gross weight and soak 25 minutes, carry out
Decoct for the first time, at a simmer front employing intense fire is decocted, and with being cooked by slow fire 50 minutes after boiling, is leached medicinal liquid, is obtained filtering residue, second decocts
Boil, add 4.5 times of medical material gross weight, after the boiling of big fire water, be cooked by slow fire 25 minutes, leach medicinal liquid, be concentrated into finite concentration, freeze
Dry, obtain powder, 5g mono- is encapsulated.
Embodiment 3
The pharmaceutical formulation for the treatment of bronchitis, which is made up of following components by weight percent：Bulbus Fritillariae Thunbergii 15g, Radix Astragali 15g, Poria 15g,
Cortex Lycii 10g, Folium Mori 15g, Radix Glehniae 8g, Radix Asparagi 12g, Fructus Schisandrae Chinensis 8g, Radix Ginseng 10g, Rhizoma Pinelliae 8g, Radix Panacis Quinquefolii 8g, Fructus Jujubae 5g, Folium Eriobotryae
Leaf 9g, Bulbus Lilii 6g, Pericarpium Citri Reticulatae 8g, Fructus Perillae 4g, Fructus Psoraleae 6g, Semen Juglandis 4g, thin 4-6g, Radix Aconiti Lateralis Preparata 4g, Placenta Hominiss 5g, Rhizoma Zingiberiss 3g, Roripa
Li 5g and Rhizoma Polygonati 1g.
Preparation method comprises the steps：
Medical material is weighed by formula, clean for medical material, chopping post-drying is then less than to water content by the medical material mix homogeneously for weighing
1%, then it is ground, is sieved using the sieve of 80 mesh, adds in 9 times of water of medical material gross weight and soak 25 minutes, carry out
Decoct for the first time, at a simmer front employing intense fire is decocted, and with being cooked by slow fire 50 minutes after boiling, is leached medicinal liquid, is obtained filtering residue, second decocts
Boil, add 4.5 times of medical material gross weight, after the boiling of big fire water, be cooked by slow fire 20-30 minutes, leach medicinal liquid, be concentrated into finite concentration,
Lyophilization, obtains powder, and 5g mono- is encapsulated.
Embodiment 4
The pharmaceutical formulation for the treatment of bronchitis, which is made up of following components by weight percent：Bulbus Fritillariae Thunbergii 15g, Radix Astragali 15g, Poria 10g,
Cortex Lycii 15g, Folium Mori 10g, Radix Glehniae 11g, Radix Asparagi 9g, Fructus Schisandrae Chinensis 10g, Radix Ginseng 10g, Rhizoma Pinelliae 8g, Radix Panacis Quinquefolii 6g, Fructus Jujubae 7g, Pi
Rake leaf 9g, Bulbus Lilii 6g, Pericarpium Citri Reticulatae 8g, Fructus Perillae 5g, Fructus Psoraleae 6g, Semen Juglandis 4g, Herba Asari 6g, Radix Aconiti Lateralis Preparata 5g, Placenta Hominiss 5g, Rhizoma Zingiberiss 3g,
Semen Lepidii (Semen Descurainiae) 5g and Rhizoma Polygonati 3g.
Preparation method comprises the steps：
Medical material is weighed by formula, clean for medical material, chopping post-drying is then less than to water content by the medical material mix homogeneously for weighing
1%, then it is ground, is sieved using the sieve of 80 mesh, adds in 9 times of water of medical material gross weight and soak 25 minutes, carry out
Decoct for the first time, at a simmer front employing intense fire is decocted, and with being cooked by slow fire 50 minutes after boiling, is leached medicinal liquid, is obtained filtering residue, second decocts
Boil, add 4.5 times of medical material gross weight, after the boiling of big fire water, be cooked by slow fire 25 minutes, leach medicinal liquid, be concentrated into finite concentration, freeze
Dry, obtain powder, 5g mono- is encapsulated.
Clinical trial
The clinical treatment observation of the present invention is as follows：
1 physical data
Patient 200,104 is male, and 96 is women.
2 diagnostic criterias
Diagnostic criteria：Reference《Internal medicine》In diagnosis basis carry out clinical diagnosises, it is to be diagnosed as bronchitis to enter a group case
Patient.
3 Therapeutic Method take the capsule of embodiment 1, and twice daily, sooner or later respectively once, course for the treatment of on the 7th takes two treatments
Journey.
(4) efficacy assessment standard：
Overall efficacy evaluation reference《New Chinese medicine guideline of clinical investigations》Relevant criterion：
Cure：Cough, expectoration, asthma symptom disappear, can normal work and life；
Effectively：Cough, expectoration, asthma symptom mitigate, and respiratory function improves；
Invalid：Symptom, sign are without improvement.
(5) therapeutic outcome
Recovery from illness 182, effective 18, cure rate is 91%, and effective percentage is 100%.
Finally it should be noted that：Above example only in order to technical scheme to be described, rather than a limitation；Although
With reference to the foregoing embodiments the present invention has been described in detail, it will be understood by those within the art that：Which still may be used
To modify to the technical scheme described in previous embodiment, or equivalent is carried out to which part technical characteristic；And
These modifications are replaced, and do not make the essence of appropriate technical solution depart from spirit and the model of embodiment of the present invention technical scheme
Enclose.
Claims (4)
1. a kind of pharmaceutical formulation for treating bronchitis, it is characterised in which is made up of following parts by weight of component：Bulbus Fritillariae Thunbergii 15-
20 parts, Radix Astragali 10-15 parts, Poria 10-15 parts, Cortex Lycii 10-15 parts, Folium Mori 10-15 parts, Radix Glehniae 8-12 parts, Radix Asparagi 8-12
Part, Fructus Schisandrae Chinensis 8-10 parts, Radix Ginseng 8-10 parts, Rhizoma Pinelliae 8-10 parts, Radix Panacis Quinquefolii 6-8 parts, Fructus Jujubae 5-10 parts, Folium Eriobotryae 7-9 parts, Bulbus Lilii
6-8 parts, Pericarpium Citri Reticulatae 6-8 parts, Fructus Perillae 4-7 part, Fructus Psoraleae 4-6 parts, Semen Juglandis 4-6 parts, Herba Asari 4-6 parts, Radix Aconiti Lateralis Preparata 4-6 parts, Placenta Hominiss
3-5 parts, Rhizoma Zingiberiss 3-5 parts, Semen Lepidii (Semen Descurainiae) 3-5 parts and Rhizoma Polygonati 1-3 parts.
2. a kind of pharmaceutical formulation for treating bronchitis according to claim 1, it is characterised in which is by following weight portion
Group is grouped into：18 parts of Bulbus Fritillariae Thunbergii, 13 parts of the Radix Astragali, 13 parts of Poria, 12 parts of Cortex Lycii, 12 parts of Folium Mori, 10 parts of Radix Glehniae, Radix Asparagi 10
Part, 9 parts of Fructus Schisandrae Chinensis, 9 parts of Radix Ginseng, 9 parts of the Rhizoma Pinelliae, 7 parts of Radix Panacis Quinquefolii, 7 parts of Fructus Jujubae, 8 parts of Folium Eriobotryae, 7 parts of Bulbus Lilii, 7 parts of Pericarpium Citri Reticulatae, Fructus Perillae
2 parts of 6 parts, 5 parts of Fructus Psoraleae, 5 parts of Semen Juglandis, 5 parts of Herba Asari, 5 parts of Radix Aconiti Lateralis Preparata, 4 parts of Placenta Hominiss, 4 parts of Rhizoma Zingiberiss, 4 parts of Semen Lepidii (Semen Descurainiae) and Rhizoma Polygonati.
3. a kind of production technology of the pharmaceutical formulation for treating bronchitis as claimed in claim 1 or 2, it is characterised in that bag
Include following steps：
Medical material is weighed by formula, clean for medical material, chopping post-drying is then less than to water content by the medical material mix homogeneously for weighing
1%, then it is ground, is sieved using the sieve of 80 mesh, is added to the water immersion 20-30 minutes, carries out first time decoction,
At a simmer front employing intense fire is decocted, and with 45-60 minutes are cooked by slow fire after boiling, is leached medicinal liquid, is obtained filtering residue, and second decocts, and adds water, greatly
After fiery water boiling, 20-30 minutes are cooked by slow fire, medicinal liquid is leached, finite concentration is concentrated into, lyophilization obtains powder, encapsulated.
4. the production technology of a kind of pharmaceutical formulation for treating bronchitis according to claim 3, it is characterised in that described
To add the amount of water when decocting be 8-10 times of medical material gross mass first time, the amount for adding when decocting for described second is total for medical material
4-5 times of quality.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102940830A (en) * | 2012-11-23 | 2013-02-27 | 茆俊卿 | Ointment for tonifying lungs and relieving coughs |
| CN104758565A (en) * | 2015-03-17 | 2015-07-08 | 梁晓 | Traditional Chinese medicine composition for treating chronic bronchitis in the type of qi-deficiency of lung and spleen |
-
2016
- 2016-12-27 CN CN201611226011.7A patent/CN106492182A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102940830A (en) * | 2012-11-23 | 2013-02-27 | 茆俊卿 | Ointment for tonifying lungs and relieving coughs |
| CN104758565A (en) * | 2015-03-17 | 2015-07-08 | 梁晓 | Traditional Chinese medicine composition for treating chronic bronchitis in the type of qi-deficiency of lung and spleen |
Non-Patent Citations (1)
| Title |
|---|
| 程时平，等: "《难治内科病名医绝技》", 30 April 2012, 华中科技大学出版社 * |
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Application publication date: 20170315 |