CN106421587A - 一种治疗肾阳亏虚证的中药组合物及制备方法 - Google Patents
一种治疗肾阳亏虚证的中药组合物及制备方法 Download PDFInfo
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- CN106421587A CN106421587A CN201610992141.5A CN201610992141A CN106421587A CN 106421587 A CN106421587 A CN 106421587A CN 201610992141 A CN201610992141 A CN 201610992141A CN 106421587 A CN106421587 A CN 106421587A
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Abstract
本发明公开了一种治疗肾阳亏虚证的中药组合物及制备方法，由以下重量份的原料制成：熟地黄120‑180份、肉苁蓉120‑180份、鹿角胶70‑130份、桑椹子120‑180份、枸杞子120‑180份、茯苓200‑400份、白术170‑230份、女贞子170‑230份、狗脊170‑230份、泽泻120‑180份、山药200‑400份、覆盆子90‑150份、益智仁120‑180份、金樱子120‑180份、甘草40‑80份、山茱萸170‑230份、牡丹皮120‑180份、茯苓120‑180份、巴戟天120‑180份、淫羊藿120‑180份、苯甲酸钠0.001‑0.003份、阿斯巴甜0.001‑0.002份、山梨酸钾0.001‑0.002份。该药物为内服药，具有温补肾阳、固精缩尿的功效，且简、便、廉、验、安全舒适的特点，有独特的显著效果、天然无毒副作用。
Description
技术领域
本发明涉及中药技术领域，具体涉及一种治疗肾阳亏虚证的中药组合物及制备方法。
背景技术
肾阳亏虚证，中医病证名，是指由于肾阳虚衰，温煦失职，气化失权所表现的一类虚寒证候，称为肾阳亏虚证，根据临床表现及病机特点，其证候类型表现多种多样，病因素体阳虚，或年老肾亏，或久病伤肾，以及房劳过度；病机肾阳不足，脏腑经络失于温养，气血运行无力，不能上荣于面，故面色晄白；肾阳虚衰，不能温煦肌肤，故畏寒怕冷；肾阳虚弱，无力振奋神气，故精神不振；肾主骨，腰为肾之府，肾阳虚衰，不能温养腰府及骨骼，故腰膝酸软；舌淡胖苔白，脉沉细，均为肾阳虚衰，气血运行无力的表现；肾阳虚损，气化失常，水湿内停，下注冲任，损及任带，而致带下病，辨证要点腰膝酸软、畏寒怕冷、精神不振、舌淡胖苔白、脉沉细，此证必须经过较长期的治疗方能有显著疗效，中药治疗肾阳亏虚由于疗效显著，无毒副作用，深受群众喜爱，但是由于早年生产工艺所限，导致药材有效成分提取不充分。
发明内容
本发明针对现有技术的上述缺陷，提供一种治疗肾阳亏虚证的中药组合物及制备方法，该药物为内服药，具有温补肾阳、固精缩尿的功效，且简、便、廉、验、安全舒适的特点，有独特的显著效果、天然无毒副作用。
本发明的目的是这样实现的，所采用的技术方案为：
一种治疗肾阳亏虚证的中药组合物，由以下重量份的原料制成：熟地黄120-180份、肉苁蓉120-180份、鹿角胶70-130份、桑椹子120-180份、枸杞子120-180份、茯苓200-400份、白术170-230份、女贞子170-230份、狗脊170-230份、泽泻120-180份、山药200-400份、覆盆子90-150份、益智仁120-180份、金樱子120-180份、甘草40-80份、山茱萸170-230份、牡丹皮120-180份、茯苓120-180份、巴戟天120-180份、淫羊藿120-180份、苯甲酸钠0.001-0.003份、阿斯巴甜0.001-0.002份、山梨酸钾0.001-0.002份；
其制备步骤为：
（1）取原料熟地黄、肉苁蓉、益智仁、甘草、山茱萸、牡丹皮、茯苓、巴戟天、淫羊藿用粉碎机粉碎，细度为100-120目，得原料粉，备用；
（2）取原药材鹿角胶，除去灰屑，砸成小块，研成细粉，用粉碎机粉碎，细度为50-80目，加入其重量的2-5倍的纯净水隔水蒸至溶化，得鹿角胶液，备用；
（3）取原料桑椹子、枸杞子、覆盆子、金樱子、山药用粉碎机粉碎，细度为80-100目，得原料粉，备用；
（4）取原料茯苓、白术、女贞子、狗脊、泽泻用粉碎机粉碎，细度为10-20目，得原料粉，备用；
（5）将步骤（1）中、步骤（3）中、步骤（4）中所得原料粉混合，加入原料总重量1.5-2.5倍量的水，搅拌10-15分钟后浸渍30-60分钟，再加入原料总重量5-8倍量的水，煎煮20-80分钟，过滤，药渣再加入原料总重量4-6倍量的水煎煮20-80分钟，过滤，合并两次滤液，过滤，减压浓缩至55-60℃测相对密度为1.08-1.20的清膏，备用；
（6）将步骤（5）中所得清膏置于锅中加入其重量的3-6倍量的水，煮沸5-10分钟，同时搅拌5-10分钟，加入苯甲酸钠充分搅拌15-20分钟后静置12-48小时，过滤，得滤液，备用；
（7）将步骤（6）中所得滤液加入步骤（2）中所得鹿角胶液、再加入阿斯巴甜、山梨酸钾后煮沸15-20分钟，充分搅拌15-20分钟，两次过滤，灌装、灭菌、包装，即得治疗肾阳亏虚证的中药组合物。
作为本发明的进一步改进，所述的一种治疗肾阳亏虚证的中药组合物，由以下重量份的原料制成：熟地黄150份、肉苁蓉150份、鹿角胶100份、桑椹子150份、枸杞子150份、茯苓300份、白术200份、女贞子200份、狗脊200份、泽泻150份、山药300份、覆盆子120份、益智仁150份、金樱子150份、甘草60份、山茱萸200份、牡丹皮150份、茯苓150份、巴戟天150份、淫羊藿150份、苯甲酸钠0.002份、阿斯巴甜0.0015份、山梨酸钾0.0015份；
其制备步骤为：
（1）取原料熟地黄、肉苁蓉、益智仁、甘草、山茱萸、牡丹皮、茯苓、巴戟天、淫羊藿用粉碎机粉碎，细度为100目，得原料粉，备用；
（2）取原药材鹿角胶，除去灰屑，砸成小块，研成细粉，用粉碎机粉碎，细度为50目，加入其重量的3倍的纯净水隔水蒸至溶化，得鹿角胶液，备用；
（3）取原料桑椹子、枸杞子、覆盆子、金樱子、山药用粉碎机粉碎，细度为80目，得原料粉，备用；
（4）取原料茯苓、白术、女贞子、狗脊、泽泻用粉碎机粉碎，细度为20目，得原料粉，备用；
（5）将步骤（1）中、步骤（3）中、步骤（4）中所得原料粉混合，加入原料总重量2倍量的水，搅拌10分钟后浸渍35分钟，再加入原料总重量8倍量的水，煎煮45分钟，过滤，药渣再加入原料总重量5倍量的水煎煮45分钟，过滤，合并两次滤液，过滤，减压浓缩至60℃测相对密度为1.15的清膏，备用；
（6）将步骤（5）中所得清膏置于锅中加入其重量的5倍量的水，煮沸5分钟，同时搅拌5分钟，加入苯甲酸钠充分搅拌15分钟后静置18小时，过滤，得滤液，备用；
（7）将步骤（6）中所得滤液加入步骤（2）中所得鹿角胶液、再加入阿斯巴甜、山梨酸钾后煮沸15分钟，充分搅拌15分钟，两次过滤，灌装、灭菌、包装，即得治疗肾阳亏虚证的中药组合物。
各原料的药理作用为：
熟地黄：性味归经：甘，微温，归肝、肾经；功能主治：滋阴补血，益精填髓；用于肝肾阴虚，腰膝酸软，骨蒸潮热，盗汗遗精，内热消渴，血虚萎黄，心悸怔忡，月经不调，崩漏下血，眩晕，耳鸣，须发早白。
肉苁蓉：性味归经：甘、咸，温，归肾、大肠经；功能主治：补肾阳，益精血，润肠通便；用于阳痿，不孕，腰膝酸软，筋骨无力，肠燥便秘。
鹿角胶：性温，味甘、咸，归肝、肾经；功能主治：补精益血，安胎止血；用于：肝肾亏损，精血不足，虚劳赢瘦，头晕耳鸣，腰膝酸软，阳痿滑精，宫寒不孕，胎动不安，崩漏带下，吐血，衄血，咯血，尿血，跌打损伤，阴疽疮疡。
桑椹子：性味：味甘，性寒，归经：入心、肝、肾经；功能：滋阴补血，明目生津，润肠；主治：久病体虚，肝肾阴亏，腰膝酸软，目暗耳鸣，关节不利，肠燥便秘，津亏血少，潮热遗精，糖尿病等。
枸杞子：性味归经：甘，平，归肝、肾经；功能主治：滋补肝肾，益精明目；用于虚劳精亏，腰膝酸痛，眩晕耳鸣，内热消渴，血虚萎黄，目昏不明。
茯苓：性味归经：甘、淡，平，归心、肺、脾、肾经；功能主治：利水渗湿，健脾宁心；用于水肿尿少，痰饮眩悸，脾虚食少，便溏泄泻，心神不安，惊悸失眠。
白术：性味归经：苦、甘，温，归脾、胃经；功能主治：健脾益气，燥湿利水，止汗，安胎；用于脾虚食少，腹胀泄泻，痰饮眩悸，水肿，自汗，胎动不安。
女贞子：性味归经：甘、苦，凉，归肝、肾经；功能主治：滋补肝肾，明目乌发；用于眩晕耳鸣，腰膝酸软，须发早白，目暗不明。
狗脊：性味归经：苦、甘，温，归肝、肾经；功能主治：补肝肾，强腰脊，祛风湿；用于腰膝酸软，下肢无力，风湿痹痛。
泽泻：性味归经：甘，寒，归肾、膀胱经；功能主治：利小便，清湿热；用于小便不利，水肿胀满，泄泻尿少，痰饮眩晕，热淋涩痛；高血脂。
山药：性味归经：甘，平，归脾、肺、肾经；功能主治：补脾养胃，生津益肺，补肾涩精；用于脾虚食少，久泻不止，肺虚喘咳，肾虚遗精，带下，尿频，虚热消渴；麸炒山药补脾健胃；用于脾虚食少，泄泻便溏，白带过多。
覆盆子：性味归经：甘、酸，温，归肾、膀胱经；功能主治：益肾，固精，缩尿；用于肾虚遗尿，小便频数，阳痿早泄，遗精滑精。
益智仁：性味，味辛，性温，归心，脾；肾经；功效：温肾固精缩尿，温脾开胃摄唾；主治：脾胃虚寒，呕吐，泄泻，腹中冷育，口多唾涎，肾虚遗尿，尿频，遗精，白浊，多唾液等症。
金樱子：性味归经：酸、甘、涩，平，归肾、膀胱、大肠经；功能主治：固精缩尿，涩肠止泻；用于遗精滑精，遗尿尿频，崩漏带下，久泻久痢。
甘草：性平、味甘，归心、脾、肺、胃经；功效：补益；功能主治：补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药；用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
山茱萸：性味归经：酸、涩，微温，归肝、肾经；功能主治：补益肝肾，涩精固脱；用于眩晕耳鸣，腰膝酸痛，阳痿遗精，遗尿尿频，崩漏带下，大汗虚脱，内热消渴。
牡丹皮：性味归经：苦、辛，微寒，归心、肝、肾经；功能主治：清热凉血，活血化瘀；用于温毒发斑，吐血衄血，夜热早凉，无汗骨蒸，经闭痛经，痈肿疮毒，跌扑伤痛。
茯苓：性味归经：甘、淡，平，归心、肺、脾、肾经；功能主治：利水渗湿，健脾宁心；用于水肿尿少，痰饮眩悸，脾虚食少，便溏泄泻，心神不安，惊悸失眠。
巴戟天：性味归经：甘，辛，微温，归肾、肝经；功能主治：补肾阳，强筋骨，祛风湿；用于阳痿遗精，宫冷不孕，月经不调，少腹冷痛，风湿痹痛，筋骨痿软。
淫羊藿：性味归经：辛、甘，温，归肝、肾经；功能主治：补肾阳，强筋骨，祛风湿；用于阳痿遗精，筋骨痿软，风湿痹痛，麻木拘挛；更年期高血压。
本发明的有益效果：具有温补肾阳、固精缩尿的功效，且简、便、廉、验、安全舒适的特点，有独特的显著效果、天然无毒副作用。
具体实施方式
下面结合具体实施方式作进一步说明。
实施例1
一种治疗肾阳亏虚证的中药组合物，由以下重量份的原料制成：熟地黄180份、肉苁蓉180份、鹿角胶130份、桑椹子180份、枸杞子180份、茯苓400份、白术230份、女贞子230份、狗脊230份、泽泻180份、山药400份、覆盆子150份、益智仁180份、金樱子180份、甘草80份、山茱萸230份、牡丹皮180份、茯苓180份、巴戟天180份、淫羊藿180份、苯甲酸钠0.003份、阿斯巴甜0.002份、山梨酸钾0.002份；
其制备步骤为：
（1）取原料熟地黄、肉苁蓉、益智仁、甘草、山茱萸、牡丹皮、茯苓、巴戟天、淫羊藿用粉碎机粉碎，细度为100-120目，得原料粉，备用；
（2）取原药材鹿角胶，除去灰屑，砸成小块，研成细粉，用粉碎机粉碎，细度为50-80目，加入其重量的2-5倍的纯净水隔水蒸至溶化，得鹿角胶液，备用；
（3）取原料桑椹子、枸杞子、覆盆子、金樱子、山药用粉碎机粉碎，细度为80-100目，得原料粉，备用；
（4）取原料茯苓、白术、女贞子、狗脊、泽泻用粉碎机粉碎，细度为10-20目，得原料粉，备用；
（5）将步骤（1）中、步骤（3）中、步骤（4）中所得原料粉混合，加入原料总重量1.5-2.5倍量的水，搅拌10-15分钟后浸渍30-60分钟，再加入原料总重量5-8倍量的水，煎煮20-80分钟，过滤，药渣再加入原料总重量4-6倍量的水煎煮20-80分钟，过滤，合并两次滤液，过滤，减压浓缩至55-60℃测相对密度为1.08-1.20的清膏，备用；
（6）将步骤（5）中所得清膏置于锅中加入其重量的3-6倍量的水，煮沸5-10分钟，同时搅拌5-10分钟，加入苯甲酸钠充分搅拌15-20分钟后静置12-48小时，过滤，得滤液，备用；
（7）将步骤（6）中所得滤液加入步骤（2）中所得鹿角胶液、再加入阿斯巴甜、山梨酸钾后煮沸15-20分钟，充分搅拌15-20分钟，两次过滤，灌装、灭菌、包装，即得治疗肾阳亏虚证的中药组合物。
用法：口服，每日2次，每次15ml。
实施例2
一种治疗肾阳亏虚证的中药组合物，由以下重量份的原料制成：熟地黄150份、肉苁蓉150份、鹿角胶100份、桑椹子150份、枸杞子150份、茯苓300份、白术200份、女贞子200份、狗脊200份、泽泻150份、山药300份、覆盆子120份、益智仁150份、金樱子150份、甘草60份、山茱萸200份、牡丹皮150份、茯苓150份、巴戟天150份、淫羊藿150份、苯甲酸钠0.002份、阿斯巴甜0.0015份、山梨酸钾0.0015份；
其制备步骤为：
（1）取原料熟地黄、肉苁蓉、益智仁、甘草、山茱萸、牡丹皮、茯苓、巴戟天、淫羊藿用粉碎机粉碎，细度为100-120目，得原料粉，备用；
（2）取原药材鹿角胶，除去灰屑，砸成小块，研成细粉，用粉碎机粉碎，细度为50-80目，加入其重量的2-5倍的纯净水隔水蒸至溶化，得鹿角胶液，备用；
（3）取原料桑椹子、枸杞子、覆盆子、金樱子、山药用粉碎机粉碎，细度为80-100目，得原料粉，备用；
（4）取原料茯苓、白术、女贞子、狗脊、泽泻用粉碎机粉碎，细度为10-20目，得原料粉，备用；
（5）将步骤（1）中、步骤（3）中、步骤（4）中所得原料粉混合，加入原料总重量1.5-2.5倍量的水，搅拌10-15分钟后浸渍30-60分钟，再加入原料总重量5-8倍量的水，煎煮20-80分钟，过滤，药渣再加入原料总重量4-6倍量的水煎煮20-80分钟，过滤，合并两次滤液，过滤，减压浓缩至55-60℃测相对密度为1.08-1.20的清膏，备用；
（6）将步骤（5）中所得清膏置于锅中加入其重量的3-6倍量的水，煮沸5-10分钟，同时搅拌5-10分钟，加入苯甲酸钠充分搅拌15-20分钟后静置12-48小时，过滤，得滤液，备用；
（7）将步骤（6）中所得滤液加入步骤（2）中所得鹿角胶液、再加入阿斯巴甜、山梨酸钾后煮沸15-20分钟，充分搅拌15-20分钟，两次过滤，灌装、灭菌、包装，即得治疗肾阳亏虚证的中药组合物。
用法：口服，每日2次，每次15ml。
实施例3
一种治疗肾阳亏虚证的中药组合物，由以下重量份的原料制成：熟地黄120份、肉苁蓉120份、鹿角胶70份、桑椹子120份、枸杞子120份、茯苓200份、白术170份、女贞子170份、狗脊170份、泽泻120份、山药200份、覆盆子90份、益智仁120份、金樱子120份、甘草40份、山茱萸170份、牡丹皮120份、茯苓120份、巴戟天120份、淫羊藿120份、苯甲酸钠0.001份、阿斯巴甜0.001份、山梨酸钾0.001份；
其制备步骤为：
（1）取原料熟地黄、肉苁蓉、益智仁、甘草、山茱萸、牡丹皮、茯苓、巴戟天、淫羊藿用粉碎机粉碎，细度为100-120目，得原料粉，备用；
（2）取原药材鹿角胶，除去灰屑，砸成小块，研成细粉，用粉碎机粉碎，细度为50-80目，加入其重量的2-5倍的纯净水隔水蒸至溶化，得鹿角胶液，备用；
（3）取原料桑椹子、枸杞子、覆盆子、金樱子、山药用粉碎机粉碎，细度为80-100目，得原料粉，备用；
（4）取原料茯苓、白术、女贞子、狗脊、泽泻用粉碎机粉碎，细度为10-20目，得原料粉，备用；
（5）将步骤（1）中、步骤（3）中、步骤（4）中所得原料粉混合，加入原料总重量1.5-2.5倍量的水，搅拌10-15分钟后浸渍30-60分钟，再加入原料总重量5-8倍量的水，煎煮20-80分钟，过滤，药渣再加入原料总重量4-6倍量的水煎煮20-80分钟，过滤，合并两次滤液，过滤，减压浓缩至55-60℃测相对密度为1.08-1.20的清膏，备用；
（6）将步骤（5）中所得清膏置于锅中加入其重量的3-6倍量的水，煮沸5-10分钟，同时搅拌5-10分钟，加入苯甲酸钠充分搅拌15-20分钟后静置12-48小时，过滤，得滤液，备用；
（7）将步骤（6）中所得滤液加入步骤（2）中所得鹿角胶液、再加入阿斯巴甜、山梨酸钾后煮沸15-20分钟，充分搅拌15-20分钟，两次过滤，灌装、灭菌、包装，即得治疗肾阳亏虚证的中药组合物。
用法：口服，每日2次，每次15ml。
本发明中药组合物治疗观察肾阳亏虚患者40例，临床报告如下：
1、一般资料
临床观察肾阳亏虚患者40例，其中男10例，女30例，年龄20-75岁，平均年龄47.5岁。
2、诊断标准
证候：腰膝酸软、畏寒怕冷、精神不振、舌淡胖苔白、脉沉细；肾阳亏虚，机体失却湿煦，以畏寒肢冷，腰膝以下尤甚，面色恍白或黧黑，小便清长，夜尿多，舌淡苔白，脉弱等为常见症的证候。
3、治疗方法
使用本发明中药组合物治疗，口服本发明中药口服液，每日三次，每次15ml，7天为一个疗程。
4、疗效判定
治愈：症状消失；
有效：临床症状减轻；
无效：临床症状无改善或加重。
5、治疗结果
治疗40例肾阳亏虚患者中，治愈30例占75%，有效10例占25%，无效0例，总有效率为100%。
6、典型病例
病例1：男，26岁，主诉腰膝酸软、畏寒怕冷、精神不振、舌淡胖苔白、脉沉细，诊断为：肾阳亏虚，服用本发明中药组合物3个疗程，所有症状完全消失，痊愈，半年后随访无复发。
病例2：女，38岁，患者畏寒肢冷，腰膝以下尤甚，面色恍白，小便清长，夜尿多，舌淡苔白，脉弱，诊断为：肾阳亏虚，服用本发明中药组合物3个疗程，所有症状完全消失，痊愈，半年后随访无复发。
病例3：女，23岁，患者畏寒肢冷，面色黧黑，小便清长，夜尿多，舌淡苔白，脉弱，诊断为：肾阳亏虚，服用本发明中药组合物3个疗程，所有症状完全消失，痊愈，半年后随访无复发。
病例4：女，47岁，夜间小便频多，大便不成形，总感到怕冷，手脚冰凉，食欲不振，口泛淡水，舌淡胖苔白、脉沉细，诊断为：肾阳亏虚，服用本发明中药组合物4个疗程，所有症状完全消失，痊愈，半年后随访无复发。
以上对本发明做了详尽的描述，实施例的说明只是用于帮助理解本发明的方法及其核心思想，其目的在于让熟悉此领域技术的人士能够了解本发明的内容并据以实施，并不能以此限制本发明的保护范围；凡根据本发明精神实质所作的等效变化或修饰，都应涵盖在本发明的保护范围之内。
Claims (6)
1.一种治疗肾阳亏虚证的中药组合物，其特征在于：由以下重量份的原料制成：熟地黄120-180份、肉苁蓉120-180份、鹿角胶70-130份、桑椹子120-180份、枸杞子120-180份、茯苓200-400份、白术170-230份、女贞子170-230份、狗脊170-230份、泽泻120-180份、山药200-400份、覆盆子90-150份、益智仁120-180份、金樱子120-180份、甘草40-80份、山茱萸170-230份、牡丹皮120-180份、茯苓120-180份、巴戟天120-180份、淫羊藿120-180份、苯甲酸钠0.001-0.003份、阿斯巴甜0.001-0.002份、山梨酸钾0.001-0.002份。
2.根据权利要求1所述的一种治疗肾阳亏虚证的中药组合物的制备方法，其特征在于：其制备步骤为：
（1）取原料熟地黄、肉苁蓉、益智仁、甘草、山茱萸、牡丹皮、茯苓、巴戟天、淫羊藿用粉碎机粉碎，细度为100-120目，得原料粉，备用；
（2）取原药材鹿角胶，除去灰屑，砸成小块，研成细粉，用粉碎机粉碎，细度为50-80目，加入其重量的2-5倍的纯净水隔水蒸至溶化，得鹿角胶液，备用；
（3）取原料桑椹子、枸杞子、覆盆子、金樱子、山药用粉碎机粉碎，细度为80-100目，得原料粉，备用；
（4）取原料茯苓、白术、女贞子、狗脊、泽泻用粉碎机粉碎，细度为10-20目，得原料粉，备用；
（5）将步骤（1）中、步骤（3）中、步骤（4）中所得原料粉混合，加入原料总重量1.5-2.5倍量的水，搅拌10-15分钟后浸渍30-60分钟，再加入原料总重量5-8倍量的水，煎煮20-80分钟，过滤，药渣再加入原料总重量4-6倍量的水煎煮20-80分钟，过滤，合并两次滤液，过滤，减压浓缩至55-60℃测相对密度为1.08-1.20的清膏，备用；
（6）将步骤（5）中所得清膏置于锅中加入其重量的3-6倍量的水，煮沸5-10分钟，同时搅拌5-10分钟，加入苯甲酸钠充分搅拌15-20分钟后静置12-48小时，过滤，得滤液，备用；
（7）将步骤（6）中所得滤液加入步骤（2）中所得鹿角胶液、再加入阿斯巴甜、山梨酸钾后煮沸15-20分钟，充分搅拌15-20分钟，两次过滤，灌装、灭菌、包装，即得治疗肾阳亏虚证的中药组合物。
3.根据权利要求2所述的一种治疗肾阳亏虚证的中药组合物的制备方法，其特征在于：其制备步骤为：
（1）取原料熟地黄、肉苁蓉、益智仁、甘草、山茱萸、牡丹皮、茯苓、巴戟天、淫羊藿用粉碎机粉碎，细度为100目，得原料粉，备用；
（2）取原药材鹿角胶，除去灰屑，砸成小块，研成细粉，用粉碎机粉碎，细度为50目，加入其重量的3倍的纯净水隔水蒸至溶化，得鹿角胶液，备用；
（3）取原料桑椹子、枸杞子、覆盆子、金樱子、山药用粉碎机粉碎，细度为80目，得原料粉，备用；
（4）取原料茯苓、白术、女贞子、狗脊、泽泻用粉碎机粉碎，细度为20目，得原料粉，备用；
（5）将步骤（1）中、步骤（3）中、步骤（4）中所得原料粉混合，加入原料总重量2倍量的水，搅拌10分钟后浸渍35分钟，再加入原料总重量8倍量的水，煎煮45分钟，过滤，药渣再加入原料总重量5倍量的水煎煮45分钟，过滤，合并两次滤液，过滤，减压浓缩至60℃测相对密度为1.15的清膏，备用；
（6）将步骤（5）中所得清膏置于锅中加入其重量的5倍量的水，煮沸5分钟，同时搅拌5分钟，加入苯甲酸钠充分搅拌15分钟后静置18小时，过滤，得滤液，备用；
（7）将步骤（6）中所得滤液加入步骤（2）中所得鹿角胶液、再加入阿斯巴甜、山梨酸钾后煮沸15分钟，充分搅拌15分钟，两次过滤，灌装、灭菌、包装，即得治疗肾阳亏虚证的中药组合物。
4.根据权利要求1所述的一种治疗肾阳亏虚证的中药组合物，其特征在于：由以下重量份的原料制成：熟地黄150份、肉苁蓉150份、鹿角胶100份、桑椹子150份、枸杞子150份、茯苓300份、白术200份、女贞子200份、狗脊200份、泽泻150份、山药300份、覆盆子120份、益智仁150份、金樱子150份、甘草60份、山茱萸200份、牡丹皮150份、茯苓150份、巴戟天150份、淫羊藿150份、苯甲酸钠0.002份、阿斯巴甜0.0015份、山梨酸钾0.0015份。
5.根据权利要求1所述的一种治疗肾阳亏虚证的中药组合物及制备方法，其特征在于：由以下重量份的原料制成：熟地黄180份、肉苁蓉180份、鹿角胶130份、桑椹子180份、枸杞子180份、茯苓400份、白术230份、女贞子230份、狗脊230份、泽泻180份、山药400份、覆盆子150份、益智仁180份、金樱子180份、甘草80份、山茱萸230份、牡丹皮180份、茯苓180份、巴戟天180份、淫羊藿180份、苯甲酸钠0.003份、阿斯巴甜0.002份、山梨酸钾0.002份。
6.根据权利要求1所述的一种治疗肾阳亏虚证的中药组合物及制备方法，其特征在于：由以下重量份的原料制成：熟地黄120份、肉苁蓉120份、鹿角胶70份、桑椹子120份、枸杞子120份、茯苓200份、白术170份、女贞子170份、狗脊170份、泽泻120份、山药200份、覆盆子90份、益智仁120份、金樱子120份、甘草40份、山茱萸170份、牡丹皮120份、茯苓120份、巴戟天120份、淫羊藿120份、苯甲酸钠0.001份、阿斯巴甜0.001份、山梨酸钾0.001份。
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