CN106389743A - Traditional Chinese medicine composition for curing gastroptosis and preparation method thereof - Google Patents

Traditional Chinese medicine composition for curing gastroptosis and preparation method thereof Download PDF

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CN106389743A
CN106389743A CN201610942089.2A CN201610942089A CN106389743A CN 106389743 A CN106389743 A CN 106389743A CN 201610942089 A CN201610942089 A CN 201610942089A CN 106389743 A CN106389743 A CN 106389743A
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chinese medicine
medicine composition
gastroptosis
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赵炳兰
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

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Abstract

The invention discloses a traditional Chinese medicine composition for curing gastroptosis, wherein the traditional Chinese medicine composition is prepared from the following materials in parts by weight: 10-15 parts of roasted rhizoma atractylodis macrocephalae, 8-15 parts of poria cocos, 12-30 parts of rhizoma pinelliae preparata, 5-16 parts of honey-fried licorice roots, 5-15 parts of momordica grosvenori extract, 4-8 parts of hawthorn extract, 3-9 parts of honeysuckle extract, 2-6 parts of green tea extract, 3-6 parts of centella extract, 2-10 parts of lotus leaf extract, 2-5 parts of Chinese herbaceous peony extract, 2-5 parts of grapeseed extract, and 2-8 parts of sabal extract.

Description

A kind of Chinese medicine composition treating gastroptosis and preparation method
Technical field
The invention belongs to technical field of Chinese medicines, specifically a kind of Chinese medicine composition treating gastroptosis and preparation method.
Background technology
When gastroptosis refer to stand, the lower edge of stomach reaches pelvic cavity, and lesser gastric curvature camber line minimum point is down to interiliac line hereinafter referred to as Gastroptosis.How asymptomatic slight gastroptosis are, and it is poor that digestive tract power often in the above person of moderate, dyspeptic symptom, this disease Raw mostly is because diaphram suspension force is not enough, liver stomach, diaphragm stomach ligament hypofunction and relax, intra-abdominal pressure declines and abdominal muscle is lax etc. because Element, adds the factors such as the bodily form or body constitution, makes the fish hook that stomach is in low of pole bottom, no-station pole canopy type stomach as seen by gastroptosis.
Adopting western medicine the current treatment to gastroptosis more, but Western medicine large side effects, cure the symptoms, not the disease, treatment cost High.
Content of the invention
The purpose of the present invention, is to overcome the deficiency of existing above-mentioned technology, provides a kind of Chinese medicine composition treating gastroptosis Thing and preparation method, this Chinese medicine takes effect rapidly, and cure rate is high.
For solving the above problems, the technical solution adopted in the present invention is:
A kind of Chinese medicine composition treating gastroptosis, is made up of the crude drug of following parts by weight:Rhizoma Atractylodis Macrocephalae (parched) 10-15 part, Poria 8-15 part, Rhizoma Pinelliae 12-30 part, Radix Glycyrrhizae Preparata each 5-16 part, Fructus Momordicae extract 5-15 part, Fructus Crataegi extract 4-8 part, Flos Lonicerae Extract 3-9 part, green tea extract 2-6 part, Herba Centellae extract 3-6 part, Folium Nelumbinis extract 2-10 part, Radix Paeoniae Alba extract 2-5 Part, Semen Vitis viniferae extract 2-5 part, Saw Palmetto P.E 2-8 part.
The following is the improvement further to technique scheme:
Fructus Momordicae extract, the content of Momordica-Glycosides is containing 80%;In Fructus Crataegi extract, the content of Fructus Crataegi flavone is 20-30%.
In Flos Lonicerae extract, the content of chlorogenic acid is 5-6%;In described green tea extract, the content taste 50- of tea polyphenols 60%.
In described Herba Centellae extract, the content of asiatic acid is 30-40%;In described Folium Nelumbinis extract, lotus flavone Content is 5-10%;In Radix Paeoniae Alba extract, the content of peoniflorin is 15%-20%.
In Semen Vitis viniferae extract, anthocyanidin content is 95%.
The following is the improvement further to technique scheme:
A kind of preparation method of the Chinese medicine composition treating gastroptosis, comprises the following steps:
1)Take Rhizoma Atractylodis Macrocephalae (parched), Poria, Rhizoma Pinelliae and the Radix Glycyrrhizae Preparata of above-mentioned weight portion, mix, add 10 times of weight for the first time The water of part, soaks 3 hours, decocts boiling 20 minutes with high heat, then with boiling by slow fire 15 minutes, obtain final product first time decoction liquor, by First time decoction liquor is poured in container;Obtain medicinal liquid A;
2)Fructus Momordicae extract, Fructus Crataegi extract, Flos Lonicerae extract, green tea extract are stirred the vinegar adding 1000 parts Water;Then take supernatant within static 30 minutes;Obtain medical liquid B;
3)Herba Centellae extract 3-6 part, Folium Nelumbinis extract 2-10 part, Radix Paeoniae Alba extract 2-5 part are stirred, adds 1000 parts Aqueous alkali;Then take supernatant within static 30 minutes;Obtain medicinal liquid C;
4)By Semen Vitis viniferae extract 2-5 part, Saw Palmetto P.E 2-8 part, stir, add 1000 parts of saline solutions;Then quiet Only take supernatant within 30 minutes;Obtain medicinal liquid D;
5), by medicinal liquid A, medical liquid B, medicinal liquid C and medicinal liquid D mix, then be again heated to seethe with excitement, you can medicine of the present invention.
The following is the improvement further to technique scheme:
Described aqueous alkali is the aqueous solution of sodium bicarbonate, the mass ratio 1 of sodium bicarbonate and water:30.
The following is the improvement further to technique scheme:
Described vinegar water is the aqueous solution of vinegar, and vinegar is 1 with the mass ratio of water:10.
The following is the improvement further to technique scheme:
Described saline solution is the aqueous solution of Sal, and Sal is 1 with the mass ratio of water:15.
Described decocting device includes cylinder, and the top of described cylinder is fixedly installed lid, on the shell wall in described cylinder It is fixedly installed mounting groove, in described mounting groove, is plugged with mounting knob, described mounting knob is fixedly installed net cylinder;Described Several filtering holes are provided with net cylinder.
Rotary electric machine and fixed seat are fixedly installed on described lid, the rotary shaft of described rotary electric machine is connected with stirring Axle, described shaft extends to the bottom of cylinder;The bottom of described shaft is provided with cone bottom, and the lower section of described cone bottom sets It is equipped with copper backing, in described copper backing, is provided with passage, in described cone bottom, be fixedly installed groove.
, through rational compatibility, the synergism of each Chinese medicine, therapeutic effect is notable for the present invention, compared with application Western medicine, controls More rate is high, and instant effect has no toxic side effect, and is difficult to recur, treatment cost is low.
Invention has good curative effect to treatment gastroptosis, and has no toxic side effect, and each course for the treatment of is 2 days, takes twice daily, Can cure after taking 1~2 course for the treatment of, cure rate reaches 100%, and effective percentage reaches 100%.
Abdominal distention remission rate 90%;Epigastric discomfort remission rate 98%;Stomachache remission rate 96%;Constipation remission rate 98%.
With reference to embodiment and accompanying drawing, the present invention is further illustrated.
Brief description
Accompanying drawing 1 is the structural representation of decocting device;
Accompanying drawing 2 is the sectional view of decocting device;
Accompanying drawing 3 is the structural representation of mill copper device.
In figure:
1- lid;2- cylinder;3- mounting groove;4- net cylinder;5- rotary electric machine;6- fixed seat;7- agitating fins;8- mounting knob; 9- agitating fins afterbody;10- shaft;11- cylinder bottom;12- bores bottom;13- copper backing;14- passage;15- groove.
Specific embodiment
Embodiment 1, a kind of Chinese medicine composition treating gastroptosis, it is made up of the crude drug of following parts by weight:Rhizoma Atractylodis Macrocephalae (parched) 10 parts, 8 parts of Poria, 12 parts of Rhizoma Pinelliae, each 5 parts of Radix Glycyrrhizae Preparata, 5 parts of Fructus Momordicae extract, 4 parts of Fructus Crataegi extract, Flos Lonicerae extract 3 parts of thing, 2 parts of green tea extract, 3 parts of Herba Centellae extract, 2 parts of Folium Nelumbinis extract, 2 parts of Radix Paeoniae Alba extract, Semen Vitis viniferae extract 2 Part, 2 parts of Saw Palmetto P.E.
Embodiment 2, a kind of Chinese medicine composition treating gastroptosis, it is made up of the crude drug of following parts by weight:Rhizoma Atractylodis Macrocephalae (parched) 15 parts, 15 parts of Poria, 30 parts of Rhizoma Pinelliae, each 16 parts of Radix Glycyrrhizae Preparata, 15 parts of Fructus Momordicae extract, 8 parts of Fructus Crataegi extract, Flos Lonicerae carry 9 parts of thing, 6 parts of green tea extract, 6 parts of Herba Centellae extract, 10 parts of Folium Nelumbinis extract, 5 parts of Radix Paeoniae Alba extract, Semen Vitis viniferae is taken to extract 5 parts of thing, 8 parts of Saw Palmetto P.E.
Embodiment 3, a kind of Chinese medicine composition treating gastroptosis, it is made up of the crude drug of following parts by weight:Rhizoma Atractylodis Macrocephalae (parched) 12 parts, 10 parts of Poria, 24 parts of Rhizoma Pinelliae, each 10 parts of Radix Glycyrrhizae Preparata, 10 parts of Fructus Momordicae extract, 6 parts of Fructus Crataegi extract, Flos Lonicerae carry 6 parts of thing, 4 parts of green tea extract, 4 parts of Herba Centellae extract, 7 parts of Folium Nelumbinis extract, 4 parts of Radix Paeoniae Alba extract, Semen Vitis viniferae is taken to extract 3 parts of thing, 5 parts of Saw Palmetto P.E.
Fructus Momordicae extract, the content of Momordica-Glycosides is containing 80%;In Fructus Crataegi extract, the content of Fructus Crataegi flavone is 20- 30%.
In Flos Lonicerae extract, the content of chlorogenic acid is 5-6%;In described green tea extract, the content taste 50- of tea polyphenols 60%.
In described Herba Centellae extract, the content of asiatic acid is 30-40%;In described Folium Nelumbinis extract, lotus flavone Content is 5-10%;In Radix Paeoniae Alba extract, the content of peoniflorin is 15%-20%.
In Semen Vitis viniferae extract, anthocyanidin content is 95%.
A kind of preparation method of the Chinese medicine composition treating gastroptosis, comprises the following steps:
1)The Rhizoma Atractylodis Macrocephalae (parched), Poria, Rhizoma Pinelliae and the Radix Glycyrrhizae Preparata that take above-mentioned weight portion are added to decocting device, add 10 times of weights for the first time The water of amount part, soaks 3 hours, decocts boiling 20 minutes with high heat, then with boiling by slow fire 15 minutes, obtain final product first time decoction liquor, First time decoction liquor is poured in container;Obtain medicinal liquid A;
2)Fructus Momordicae extract, Fructus Crataegi extract, Flos Lonicerae extract, green tea extract are stirred the vinegar adding 1000 parts Water;Then take supernatant within static 30 minutes;Obtain medical liquid B;
3)Herba Centellae extract 3-6 part, Folium Nelumbinis extract 2-10 part, Radix Paeoniae Alba extract 2-5 part are stirred, adds 1000 parts Aqueous alkali;Then take supernatant within static 30 minutes;Obtain medicinal liquid C;
4)By Semen Vitis viniferae extract 2-5 part, Saw Palmetto P.E 2-8 part, stir, add 1000 parts of saline solutions;Then quiet Only take supernatant within 30 minutes;Obtain medicinal liquid D;
5), by medicinal liquid A, medical liquid B, medicinal liquid C and medicinal liquid D mix, then be again heated to seethe with excitement, you can medicine of the present invention.
Described aqueous alkali is the aqueous solution of sodium bicarbonate, the mass ratio 1 of sodium bicarbonate and water:30.
Described vinegar water is the aqueous solution of vinegar, and vinegar is 1 with the mass ratio of water:10.
Described saline solution is the aqueous solution of Sal, and Sal is 1 with the mass ratio of water:15.
Described decocting device includes cylinder 2, and the top of described cylinder 2 is fixedly installed lid 1, the shell in described cylinder 2 Mounting groove 3 is fixedly installed on wall, is plugged with mounting knob 8 in described mounting groove 3, described mounting knob 8 is fixedly installed Net cylinder 4;It is provided with several filtering holes on described net cylinder 4.
Rotary electric machine 5 and fixed seat 6 are fixedly installed on described lid 1, the rotary shaft of described rotary electric machine 5 is connected with to be stirred Mix axle 10, described shaft 10 extends to the bottom of cylinder 2;The bottom of described rotary electric machine 5 is provided with cone bottom 12, described cone The lower section of bottom 12 is provided with copper backing 13, is provided with passage 14, is fixedly installed in described cone bottom 12 in described copper backing 13 There is groove 15.
The bottom of cylinder 2 is provided with a bottom 11.
It is provided with described copper backing and bore the groove matching in bottom 12, cone bottom 12 and groove interference fit.
Three groups of agitating fins 7 are provided with described rotary shaft, described agitating fins 7 be three groups, on the rotating shaft to Under set gradually.
Described agitating fins are right angled triangle, and described minor face compares 1 with the length on long side:3.
Agitating fins are connected with agitating fins afterbody 9, and described agitating fins afterbody is rectangular sheet structure, described stirring wing The length-width ratio 2 of piece:3.
When rotary shaft rotates, copper backing 13 is rubbed with cone bottom 12.
For investigating clinical efficacy and the safety of above-described embodiment medicine further, we have selected 360 gastroptosis Case carries out clinical trial to the treatment curative effect of medicine of the present invention.
The patient of 360 gastroptosis is randomly divided into four groups of groups, every group 90;Each group case is in sex, age, course of disease etc. Aspect, through statistical analysis, has comparability.
Matched group adopts appropriate exercise, rational diet, and oral motilium is treated;It is made that treatment group is administered orally the present embodiment The medicine obtaining, taken three times a day, 1 dose every time, 2 days is a course for the treatment of, takes 1~2 course for the treatment of.
Criterion of therapeutical effect:Cure:Symptom all disappears, and main Physico-chemical tests index is normally;Effective:Symptomatology disappears Or cardinal symptom disappears, main Physico-chemical tests index is normal;Effectively:Cardinal symptom disappears substantially, and main Physico-chemical tests refer to Mark makes moderate progress;Invalid:Main Physico-chemical tests index with treat before unchanged.Curative effect comparision result after two groups of case treatments is such as Table one.
Table one
Group Number of cases Cure(%) Effective(%) Effectively(%) Invalid(%)
Matched group 90 83 87 90 10
Embodiment 1 90 100 100 100 0
Embodiment 2 90 100 100 100 0
Embodiment 3 90 100 100 100 0
By above-mentioned comparison it can be seen that using treatment by Chinese herbs gastroptosis of the present invention, therapeutic effect is notable, with existing Chinese and Western medicine phases Cure rate is high, instant effect for ratio.
Invention has good curative effect to treatment gastroptosis, and has no toxic side effect, and each course for the treatment of is 2 days, takes twice daily, Can cure after taking 1~2 course for the treatment of, cure rate reaches 100%, and effective percentage reaches 100%.
Medication two days, detects each symptom of patient, is shown in Table two.
Table two
Abdominal distention remission rate 90%;Epigastric discomfort remission rate 98%;Stomachache remission rate 96%;Constipation remission rate 98%.
It is as follows that some patientss cure case:
Sun, man, 15 years old, suffers from gastroptosis, after taking 1 course for the treatment of of medicine obtained by the present embodiment, patients symptomatic disappears, and fullys recover from an illness More.
In certain, male, 32 years old, suffer from gastroptosis, after taking 2 courses for the treatment of of medicine obtained by the present embodiment, patients symptomatic disappears, Recovery from illness.
Hair certain, female, 52 years old, suffer from gastroptosis, after taking 1 course for the treatment of of medicine obtained by the present embodiment, patients symptomatic disappear, Recovery from illness.

Claims (10)

1. a kind of Chinese medicine composition treating gastroptosis it is characterised in that:It is made up of the crude drug of following parts by weight:Rhizoma Atractylodis Macrocephalae (parched) 10-15 part, Poria 8-15 part, Rhizoma Pinelliae 12-30 part, Radix Glycyrrhizae Preparata each 5-16 part, Fructus Momordicae extract 5-15 part, Fructus Crataegi extract 4-8 part, Flos Lonicerae extract 3-9 part, green tea extract 2-6 part, Herba Centellae extract 3-6 part, Folium Nelumbinis extract 2-10 part, Chinese herbaceous peony Medicament extract 2-5 part, Semen Vitis viniferae extract 2-5 part, Saw Palmetto P.E 2-8 part.
2. as claimed in claim 1 a kind of Chinese medicine composition treating gastroptosis it is characterised in that:
Fructus Momordicae extract, the content of Momordica-Glycosides is containing 80%;In Fructus Crataegi extract, the content of Fructus Crataegi flavone is 20-30%.
3. as claimed in claim 1 a kind of Chinese medicine composition treating gastroptosis it is characterised in that:In Flos Lonicerae extract, The content of chlorogenic acid is 5-6%;In described green tea extract, the content taste 50-60% of tea polyphenols.
4. as claimed in claim 1 a kind of Chinese medicine composition treating gastroptosis it is characterised in that:Described Herba Centellae extract In, the content of asiatic acid is 30-40%;In described Folium Nelumbinis extract, the content of lotus flavone is 5-10%;Radix Paeoniae Alba extract In, the content of peoniflorin is 15%-20%.
5. as claimed in claim 1 a kind of Chinese medicine composition treating gastroptosis it is characterised in that:In Semen Vitis viniferae extract, Anthocyanidin content is 95%.
6. as claimed in claim 1 a kind of Chinese medicine composition treating gastroptosis it is characterised in that:
Described aqueous alkali is the aqueous solution of sodium bicarbonate, the mass ratio 1 of sodium bicarbonate and water:30.
7. as claimed in claim 1 a kind of Chinese medicine composition treating gastroptosis it is characterised in that:
Described vinegar water is the aqueous solution of vinegar, and vinegar is 1 with the mass ratio of water:10.
8. as claimed in claim 1 a kind of Chinese medicine composition treating gastroptosis it is characterised in that:
Described saline solution is the aqueous solution of Sal, and Sal is 1 with the mass ratio of water:15.
9. as claimed in claim 1 a kind of preparation method of the Chinese medicine composition treating gastroptosis it is characterised in that:Including with Lower step:
1)Take Rhizoma Atractylodis Macrocephalae (parched), Poria, Rhizoma Pinelliae and the Radix Glycyrrhizae Preparata of above-mentioned weight portion, be added in decocting device, add 10 for the first time The water of times weight portion, soaks 3 hours, decocts boiling 20 minutes with high heat, then with boiling by slow fire 15 minutes, obtains final product decoction for the first time Liquid, first time decoction liquor is poured in container;Obtain medicinal liquid A;
2)Fructus Momordicae extract, Fructus Crataegi extract, Flos Lonicerae extract, green tea extract are stirred the vinegar adding 1000 parts Water;Then take supernatant within static 30 minutes;Obtain medical liquid B;
3)Herba Centellae extract 3-6 part, Folium Nelumbinis extract 2-10 part, Radix Paeoniae Alba extract 2-5 part are stirred, adds 1000 parts Aqueous alkali;Then take supernatant within static 30 minutes;Obtain medicinal liquid C;
4)By Semen Vitis viniferae extract 2-5 part, Saw Palmetto P.E 2-8 part, stir, add 1000 parts of saline solutions;Then quiet Only take supernatant within 30 minutes;Obtain medicinal liquid D;
5), by medicinal liquid A, medical liquid B, medicinal liquid C and medicinal liquid D mix, then be again heated to seethe with excitement, you can medicine of the present invention.
10. as claimed in claim 9 a kind of preparation method of the Chinese medicine composition treating gastroptosis it is characterised in that:Described Decocting device includes cylinder(2), described cylinder(2)Top be fixedly installed lid(1), described cylinder(2)On interior shell wall It is fixedly installed mounting groove(3), described mounting groove(3)Inside it is plugged with mounting knob(8), described mounting knob(8)Upper fixation sets It is equipped with net cylinder(4);Described net cylinder(4)On be provided with several filtering holes;
It is fixedly installed rotary electric machine on described lid (1)(5)And fixed seat(6), described rotary electric machine(5)Rotary shaft connect There is shaft (10), described shaft (10) extends to the bottom of cylinder (2);The bottom of described shaft (10) is provided with cone bottom Portion (12), the lower section of described cone bottom (12) is provided with copper backing (13), is provided with passage (14), institute in described copper backing (13) State in cone bottom (12) and be fixedly installed groove (15).
CN201610942089.2A 2016-10-26 2016-10-26 Traditional Chinese medicine composition for curing gastroptosis and preparation method thereof Pending CN106389743A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1682678A (en) * 2004-04-16 2005-10-19 赵履祥 Decocting and percolating type continuous extracting device for Chinese medicine and its extracting method
CN101081274A (en) * 2006-05-30 2007-12-05 林静 Chinese medicinal materials composition for treating gastroptosis and the processing
CN103301438A (en) * 2013-07-08 2013-09-18 朱克兰 Traditional Chinese medicine composition for treating gastroptosis and preparation method thereof
CN104189752A (en) * 2014-08-20 2014-12-10 商西丹 Oral traditional Chinese medicine composition for treating gastroptosis
CN105497738A (en) * 2014-09-24 2016-04-20 陈玉梅 Gastroptosis treating traditional Chinese medicine composition

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1682678A (en) * 2004-04-16 2005-10-19 赵履祥 Decocting and percolating type continuous extracting device for Chinese medicine and its extracting method
CN101081274A (en) * 2006-05-30 2007-12-05 林静 Chinese medicinal materials composition for treating gastroptosis and the processing
CN103301438A (en) * 2013-07-08 2013-09-18 朱克兰 Traditional Chinese medicine composition for treating gastroptosis and preparation method thereof
CN104189752A (en) * 2014-08-20 2014-12-10 商西丹 Oral traditional Chinese medicine composition for treating gastroptosis
CN105497738A (en) * 2014-09-24 2016-04-20 陈玉梅 Gastroptosis treating traditional Chinese medicine composition

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Application publication date: 20170215