CN106310064A - 一种治疗咳嗽的新型中药组合物及其制备方法 - Google Patents

一种治疗咳嗽的新型中药组合物及其制备方法 Download PDF

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CN106310064A
CN106310064A CN201610865917.7A CN201610865917A CN106310064A CN 106310064 A CN106310064 A CN 106310064A CN 201610865917 A CN201610865917 A CN 201610865917A CN 106310064 A CN106310064 A CN 106310064A
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孙思远
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Sichuan Yichuang Biotechnology Co Ltd
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Abstract

本发明属于中药制剂领域,目的是根据中医对咳嗽的认识机理而提供的一种治疗咳嗽的新型中药组合物,所述中药组合物的各个组分及其质量份比如下:百部、杏仁、前胡、陈皮、款冬花、全瓜蒌、麦冬、紫苏、荆芥、防风、黄芩、法半夏、桔梗、旋复花、石膏、贝母、款冬花、甘草、天竺黄、海浮石、竹沥、紫苑、葶苈子、白前、白果、桑白皮、蒲公英、枇杷叶、连翘、金银花、白芍;本发明提供的药物是一个标本兼治的中药组方。

Description

一种治疗咳嗽的新型中药组合物及其制备方法
技术领域
[0001]本发明属于中药制剂领域,具体涉及一种治疗咳嗽的新型中药组合物,特别是供咳嗽患者使用的新型中药组合物及其制备方法的领域。
背景技术
[0002]咳嗽是人体清除呼吸道内的分泌物或异物的保护性呼吸反射动作。虽然有其有利的一面,但剧烈长期咳嗽可导致呼吸道出血。正确区分一般咳嗽和咳嗽变异性哮喘,防止误诊。治疗咳嗽应区分咳嗽类型,西药、中药皆可,但以食疗为最佳。
[0003]中医认为:咳嗽是因外感六淫,脏腑内伤,影响于肺所致有声有痰之症。见《素问.五脏生成篇》ο《素问病机气宜保命集》:“咳谓无痰而有声,肺气伤而不清也;嗽是无声而有痰,脾湿动而为痰也。咳嗽谓有痰而有声,盖因伤于肺气动于脾湿,咳而为嗽也”。因外邪犯肺,或脏腑内伤,累及于肺所致。
[0004]那么,就如何找到一种可有效治疗咳嗽的中药组合物,是我们目前急需要解决的问题。
发明内容
[0005]随着我国中医中药学的不断发展,在治疗咳嗽上,人们逐渐意识到了中医治疗咳嗽的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗咳嗽的现状,本发明的目的是在于提供一种治疗咳嗽的新型中药组合物,以解决咳嗽患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及其质量份比,可有效治疗上述咳嗽。
[0006]为达到上述发明的目的,本发明所采用的技术方案为:提供一种治疗咳嗽的新型中药组合物及其制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
百部30〜100g、杏仁80〜160g、前胡50〜120g、陈皮30〜120g、款冬花30〜160g、全瓜蒌150〜220g、麦冬100〜220g、紫苏100〜320g、荆芥80〜160g、防风50〜120g、黄芩50〜150g、法半夏30〜100g、桔梗50〜120g、旋复花30〜120g、石膏150〜480g、贝母30〜100g、款冬花30〜150g、甘草30〜120g、天竺黄30〜100g、海浮石150〜260g、竹浙300〜600g、紫苑45〜120g、葶苈子30〜100g、白前30〜100g、白果45〜100g、桑白皮90〜160g、蒲公英100〜300g、枇杷叶100〜160g、连翘150〜260g、金银花100〜300g、白芍50〜120g。
[0007] —种治疗咳嗽的新型中药组合物及其制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
百部35〜90g、杏仁90〜140g、前胡60〜105g、陈皮35〜105g、款冬花35〜140g、全瓜蒌170〜200g、麦冬115〜200g、紫苏115〜280g、荆芥90〜140g、防风60〜105g、黄芩60〜130g、法半夏35〜90g、桔梗60〜105g、旋复花35〜105g、石膏170〜420g、贝母35〜90g、款冬花35〜130g、甘草35〜105g、天竺黄35〜90g、海浮石170〜230g、竹浙350〜500g、紫苑50〜105g、葶苈子35〜90g、白前35〜90g、白果50〜90g、桑白皮100〜140g、蒲公英115〜250g、枇杷叶115〜140g、连翘170〜230g、金银花115〜250g、白芍60〜105g。
[0008] —种治疗咳嗽的新型中药组合物及其制备方法,其特征在于,所述“最佳方案”的中药组合物的各个组分及其质量份比如下所示:
百部80g、杏仁120g、前胡90g、陈皮90g、款冬花120g、全瓜蒌170g、麦冬170g、紫苏250g、荆芥120g、防风90g、黄苳115g、法半夏80g、桔梗90g、旋复花90g、石膏380g、贝母80g、款冬花11(^、甘草958、天竺黄8(^、海浮石20(^、竹沥42(^、紫苑9(^、葶苈子8(^、白前8(^、白果8(^、桑白皮120g、蒲公英220g、枇杷叶120g、连翘200g、金银花220g、白芍90g。
[0009] —种治疗咳嗽的新型中药组合物及其制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、将上述原料中药拣去杂质、粉尘及干燥后,按照质量份比共研为极细末待用;
B、按照传统制备中药水丸剂的方法,将研磨好的极细末药物过筛后,放入药器中混合拌均,然后制备成水丸剂(其水丸的粒度为:4.7_〜4.8mm),进而晒干,分装密封即可。
[0010] —种治疗咳嗽的新型中药组合物及其制备方法,其特征在于,所述服用方法为:将制备好的水丸剂药物以每日三次服用,早中晚各服一次,给药量5g /次,温水送服。服药3〜5个疗程后,症状消失,病获痊愈。
[0011]本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
百部,性味:味甘、苦、性微温,具有润肺止咳、杀虫之功效,用于治疗寒热咳嗽、肺结核咳嗽、百日咳、外用于头虱、蛲虫病、阴痒等症;
杏仁,性味:味苦、性微温,具有降气止咳平喘、润肠通便之功效,用于治疗咳嗽气喘、胸满痰多、血虚津枯、肠燥便秘;
前胡,性味:味苦、辛、性微寒,具有疏散风热、降气化痰之功效,用于治疗外感风热、肺热痰郁、咳喘痰多、痰黄稠粘、哎逆食少、胸膈满闷;
陈皮,性味:味辛、苦、性温,具有理气和中,燥湿化痰,利水通便之功效,用于治疗脾胃不和、脘腹胀痛、不思饮食、呕吐唆逆、痰湿阻肺、咳嗽痰多、胸膈满闷、头目眩晕、水肿、小便不利、大便秘结、乳痈疥癣、中鱼蟹毒、酒毒等;
款冬花,性味:辛、温,具有润肺下气、化痰止嗽之功效,用于治疗咳逆喘息、喉痹;全瓜蒌,性味:甘苦、寒,具有润肺、化痰、散结、润肠之功效,用于治疗痰热咳嗽、胸痹、结胸、肺痿咳血、消渴、黄疸、便秘、痈肿初起;
麦冬,性味:甘、微苦、微寒,具有养阴生津、润肺清心之功效,用于治疗肺燥干咳、虚痨咳嗽、津伤口渴、心烦失眠、内热消渴、肠燥便秘、咽白喉等症;
紫苏,性味:味辛、性凉,具有发表宣肺、清热解毒之功效,用于治疗风热感冒、岳热咳嗽、咽喉肿痛、疮疖肿毒;
荆芥,性味:辛、温,具有发表、祛风、理血、炒炭止血之功效,用于治疗感冒发热、头痛、咽喉肿痛、中风□噤、吐血、衄血、便血、崩漏、产后血晕、痈肿、疮疥、瘰疬;
防风,性味:味辛、甘、性微温,具有祛风解表、胜湿止痛、解痉、止痒之功效,用于治疗外感风寒、头痛身痛、风湿痹痛、骨节酸痛、腹痛泄泻、肠风下血、破伤风、风疹瘙痒、疮疡初起;黄芩,性味:味苦、性寒,具有清热泻火、燥湿解毒、止血、安胎之功效,用于治疗肺热咳嗽、热病高热神昏、肝火头痛、目赤肿痛、湿热黄疸、泻痢、热淋、吐衄血、崩漏、胎热不安、痈肿疗疮等症;
法半夏,性味:辛、温,具有燥湿化痰之功效,用于治疗痰多咳喘、痰饮眩悸、风痰眩晕、痰厥头痛;
桔梗,性味:味苦、辛、性平,具有宣肺、祛痰、利咽、排脓之功效,用于治疗咳嗽痰多、咽喉肿痛、肺痈吐脓、胞满胁痛、痢疾腹痛、小便癃闭、胸闷不畅、音哑、肺痈吐脓、疮疡脓成不溃;
旋复花,性味:味苦、辛、咸、微温,具有消痰行水、降气止呕之功效,用于治疗咳喘痰粘、哆嗦噫气、胸痞胁痛;
石膏,性味:辛甘、寒、无毒,具有解肌清热、除烦止渴之功效,用于治疗热病壮热不退、心烦神昏、谵语发狂、口渴咽干、肺热喘急、中暑自汗、胃火头痛、胃火牙痛、热毒壅盛、发斑发疹、口舌生疮、痈疽疮疡、溃不收口、汤火烫伤;
贝母,性味:苦、甘、微寒,具有清热润肺、化痰止咳之功效,用于治疗肺热燥咳、干咳少痰、阴虚劳嗽、咯痰带血,治虚劳咳嗽、吐痰咯血、心胸郁街、肺痿、肺痈、喉痹、乳痈;
款冬花,性味:辛、温,具有润肺下气、化痰止嗽之功效,用于治疗咳逆喘息、喉痹;
甘草,性味:甘、平,具有益气补中、缓急止痛、润肺止咳、泻火解毒、调和诸药之功效,用于治疗倦怠食少、肌瘦面黄、心悸气短、腹痛便溏、四肢挛急疼痛、脏躁、咳嗽气喘、咽喉肿痛、痈疮肿痛、小儿胎毒及药物、食物中毒;
天竺黄,性味:甘、寒,具有清热豁痰、凉心定惊之功效,用于治疗热病神昏、中风痰迷、小儿痰热惊痫、抽搐、夜啼;
海浮石,性味:成、寒,具有清肺火、化老痰、软坚、通淋之功效,用于治疗痰热喘嗽、老痰积块、癭瘤、瘰疬、淋病、油气、疮肿、目翳;
竹沥,性味:甘、苦、寒,具有清热降火、滑痰利窍之功效,用于治疗中风痰迷、肺热痰壅、惊风、癫痫、热病痰多、壮热烦渴、子烦、破伤风;
紫苑,性味:味苦、辛、性温,具有润肺下气、化痰止咳之功效,用于治疗咳嗽、肺虚劳嗽、肺痿肺痈、咳吐脓血、小便不利;
葶苈子,性味:辛、苦、寒,具有泻肺降气、祛痰平喘、利水消肿、泄逐邪之功效,用于治疗痰涎壅肺之喘咳痰多、肺痈、水肿、胸腹积水、小便不利、慢性肺源性心脏病、心力衰竭之喘月中、療痛结核;
白前,性味:辛、苦、微温,具有降气、消痰、止咳之功效,用于治疗肺气壅实、咳嗽痰多、胸ί两P而急;
白果,性味:甘、苦、湿、平,有毒,具有敛肺定喘,止带池,缩小便之功效,用于治疗痰多喘咳、带下白浊、遗尿尿频;
桑白皮,性味:甘、辛、性寒,具有泻肺平喘、利水消肿之功效,用于治疗肺热喘痰、水饮停肺、胀满喘急、水肿、脚气、小便不利;
蒲公英,性味:味苦、甘、性寒,具有清热解毒、消痈散结的功效,用于治疗乳痈、肺痈、肠痈、痄腮、疔毒疮肿、目赤肿痛、感冒发热、咳嗽、咽喉肿痛、胃火、肠炎、痢疾、肝炎、胆吓炎、尿路感染、蛇虫咬伤;
枇杷,性味:苦、辛、寒,无毒,具有清肺止咳,和胃降逆,止渴之功效,用于治疗肺热痰嗽、阴虚劳嗽、咳血、衄血、胃热呕哕;等症;
连翘,性味:味苦、性微寒,具有清热解毒、散结消肿之功效,用于治疗风热感冒、温病初起、炎喉肿痛、斑疹、丹毒、痈结肿毒、淋巴结结核、高烧烦渴、神昏发斑、瘰疠、尿路感染等症;
金银花,性味:性寒、味甘、气平,具有清热解毒之功效,用于治疗热毒肿疡、痈疽疔疮等症,由于兼有宣散作用,故又可治疗外感风热和温病初起;
白芍,性味:苦、酸、微寒,具有养血和营、缓急止痛、敛阴平肝之功效,用于治疗月经不调、经行腹痛、崩漏、自汗、盗汗、胁肋脘腹疼痛、四肢挛痛、头痛、眩晕。
[0012]本发明药物是基于中医治疗咳嗽的原则,从药理作用及作用机制认为:就咳嗽一证,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
[0013]本发明就是针对上述咳嗽的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种治疗咳嗽的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
百部80g、杏仁120g、前胡90g、陈皮90g、款冬花120g、全瓜蒌170g、麦冬170g、紫苏250g、荆芥120g、防风90g、黄苳115g、法半夏80g、桔梗90g、旋复花90g、石膏380g、贝母80g、款冬花11(^、甘草958、天竺黄8(^、海浮石20(^、竹沥42(^、紫苑9(^、葶苈子8(^、白前8(^、白果8(^、桑白皮120g、蒲公英220g、枇杷叶120g、连翘200g、金银花220g、白芍90g。
[0014] 实施例2:
一种治疗咳嗽的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
百部90g、杏仁140g、前胡105g、陈皮105g、款冬花140g、全瓜蒌200g、麦冬200g、紫苏280g、荆芥140g、防风105g、黄苳130g、法半夏90g、桔梗105g、旋复花105g、石膏420g、贝母90g、款冬花130g、甘草105g、天竺黄90g、海浮石230g、竹沥500g、紫苑105g、葶苈子90g、白前90g、白果90g、桑白皮140g、蒲公英250g、枇杷叶140g、连翘230g、金银花250g、白芍105g。
[0015] 实施例3:
一种治疗咳嗽的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
百部100g、杏仁160g、前胡120g、陈皮120g、款冬花160g、全瓜蒌220g、麦冬220g、紫苏320g、荆芥160g、防风120g、黄苳150g、法半夏100g、桔梗120g、旋复花120g、石膏480g、贝母100g、款冬花150g、甘草120g、天竺黄100g、海浮石260g、竹沥600g、紫苑120g、葶苈子100g、白前100g、白果100g、桑白皮160g、蒲公英300g、枇杷叶160g、连翘260g、金银花300g、白芍120go
[0016] 典型病例
经临床诊断治疗咳嗽患者共750例,年龄为13岁以上的385例,只有365例为13岁以下。 750例患者中痊愈的712例,显效的的38例,总有效率达100%。

Claims (3)

1.一种治疗咳嗽的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示: 百部30〜100g、杏仁80〜160g、前胡50〜120g、陈皮30〜120g、款冬花30〜160g、全瓜蒌150〜220g、麦冬100〜220g、紫苏100〜320g、荆芥80〜160g、防风50〜120g、黄芩50〜150g、法半夏30〜100g、桔梗50〜120g、旋复花30〜120g、石膏150〜480g、贝母30〜100g、款冬花30〜150g、甘草30〜120g、天竺黄30〜100g、海浮石150〜260g、竹浙300〜600g、紫苑45〜120g、葶苈子30〜100g、白前30〜100g、白果45〜100g、桑白皮90〜160g、蒲公英100〜300g、枇杷叶100〜160g、连翘150〜260g、金银花100〜300g、白芍50〜120g。
2.根据权利要求1所述的治疗咳嗽的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示: 百部35〜90g、杏仁90〜140g、前胡60〜105g、陈皮35〜105g、款冬花35〜140g、全瓜蒌170〜200g、麦冬115〜200g、紫苏115〜280g、荆芥90〜140g、防风60〜105g、黄芩60〜130g、法半夏35〜90g、桔梗60〜105g、旋复花35〜105g、石膏170〜420g、贝母35〜90g、款冬花35〜130g、甘草35〜105g、天竺黄35〜90g、海浮石170〜230g、竹浙350〜500g、紫苑50〜105g、葶苈子35〜90g、白前35〜90g、白果50〜90g、桑白皮100〜140g、蒲公英115〜250g、枇杷叶115〜140g、连翘170〜230g、金银花115〜250g、白芍60〜105g。
3.根据权利要求1至2所述的治疗咳嗽的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示: 百部80g、杏仁120g、前胡90g、陈皮90g、款冬花120g、全瓜蒌170g、麦冬170g、紫苏250g、荆芥120g、防风90g、黄苳115g、法半夏80g、桔梗90g、旋复花90g、石膏380g、贝母80g、款冬花11(^、甘草958、天竺黄8(^、海浮石20(^、竹沥42(^、紫苑9(^、葶苈子8(^、白前8(^、白果8(^、桑白皮120g、蒲公英220g、枇杷叶120g、连翘200g、金银花220g、白芍90g。
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106620229A (zh) * 2017-02-20 2017-05-10 成都富豪斯生物科技有限公司 一种可有效治疗咳嗽的丸剂药物及其制备方法
CN107773734A (zh) * 2017-09-28 2018-03-09 广西民族大学 一种治疗咳嗽的中药
CN108144037A (zh) * 2018-03-22 2018-06-12 复旦大学附属金山医院 一种治疗咳嗽的中药组合物及其应用
CN111419897A (zh) * 2020-05-22 2020-07-17 平顶山学院 一种防治小儿风寒感冒的药浴药物及制备方法

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106620229A (zh) * 2017-02-20 2017-05-10 成都富豪斯生物科技有限公司 一种可有效治疗咳嗽的丸剂药物及其制备方法
CN107773734A (zh) * 2017-09-28 2018-03-09 广西民族大学 一种治疗咳嗽的中药
CN108144037A (zh) * 2018-03-22 2018-06-12 复旦大学附属金山医院 一种治疗咳嗽的中药组合物及其应用
CN108144037B (zh) * 2018-03-22 2020-12-01 复旦大学附属金山医院 一种治疗咳嗽的中药组合物及其应用
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