CN106310045A - Traditional Chinese medicine composition for treating renal carcinoma - Google Patents

Traditional Chinese medicine composition for treating renal carcinoma Download PDF

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Publication number
CN106310045A
CN106310045A CN201610879987.8A CN201610879987A CN106310045A CN 106310045 A CN106310045 A CN 106310045A CN 201610879987 A CN201610879987 A CN 201610879987A CN 106310045 A CN106310045 A CN 106310045A
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CN
China
Prior art keywords
parts
chinese medicine
herba
medicine composition
traditional chinese
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Pending
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CN201610879987.8A
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Chinese (zh)
Inventor
植国繁
蒋敏捷
巫玲玲
蒋伟哲
蒋群哲
黄兴振
黄增琼
蓝彬
蓝献丽
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NANNING DUOLING BIOTECHNOLOGY CO Ltd
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NANNING DUOLING BIOTECHNOLOGY CO Ltd
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Priority to CN201610879987.8A priority Critical patent/CN106310045A/en
Publication of CN106310045A publication Critical patent/CN106310045A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/748Oldenlandia or Hedyotis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention discloses a traditional Chinese medicine composition for treating renal carcinoma, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 60 parts of radix semiaquilegiae, 60 parts of whole grass of sticktight, 60 parts of glabrous sarcandra herb, 60 parts of rhizoma smilacis glabrae, 30 parts of rhizoma polygonati, 30 parts of herba hedyotidis diffusae, 15 parts of lonicerae flos, 15 parts of herba verbenae and 15 parts of subprostrate sophora roots. The traditional Chinese medicine composition has the effects of clearing away heat and toxic materials and inducing diuresis for treating stranguria; the tumor cell growth can be effectively inhibited; cancer cells are effectively killed; the advantages of good effect and fast effect taking are achieved.

Description

A kind of Chinese medicine composition treating renal carcinoma
Technical field
The invention mainly relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine composition treating renal carcinoma.
Background technology
Renal carcinoma (renal cell carcinoma) is the tumor that in urinary system, grade of malignancy is higher, is also one of modal tumor, has been Come from the malignant tumor of excess of the kidney matter uriniferous tubule epithelial systems.According to investigations, renal carcinoma accounts in China's genitourinary system tumor Two, it is only second to tumor of bladder doctor trained in Western medicine and is mostly " with tumor for this ", take the nocuity therapies such as operation, radiotherapy, chemotherapy, a lot of patients It not to die from tumor itself, but die from over-treatment.Comparatively speaking, the Therapeutic Method of the traditional Chinese medical science is much more secure, and method has: with Poison counteracting toxic substances method, activating blood circulation to dissipate blood stasis method, the method for dissipating hard mass, consolidate and support unit's method etc..
Chinese medicine is in tumor medication market share critical role, because Chinese medicine side effect is little, determined curative effect, it is adaptable to long Phase medication, clinical practice is widely.People are effective in the urgent need to one, oneself is confirmed to play good result by most people The Chinese medicine composition for the treatment of renal carcinoma.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine composition treating renal carcinoma.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine composition treating renal carcinoma is characterized in that: is made up of the crude drug of following parts by weight: Radix Semiaquilegiae 60 parts, Herba Bidentis Bipinnatae 60 parts, Herba Sarcandrae 60 parts, Rhizoma Smilacis Glabrae 60 parts, Rhizoma Polygonati 30 parts, Herba Hedyotidis Diffusae 30 parts, Flos Lonicerae 15 parts, Herba Verbenae 15 Part, Radix Sophorae Tonkinensis 15 parts.
Concrete preparation method is: takes Radix Semiaquilegiae, Herba Bidentis Bipinnatae, Herba Sarcandrae, each 60g of Rhizoma Smilacis Glabrae and Rhizoma Polygonati, each 30g of Hedyotidis Diffusae, adds 10 90 DEG C of times amount water (V/W) heating, until concentrating is 600ml, is filtered, are obtained filtrate a;
Take Flos Lonicerae, Herba Verbenae, each 15g of Radix Sophorae Tonkinensis, with 10 times amount (V/W) 50% ethanol solution supersound extraction 1h(power 250W, frequency 40kHz), filter, filtrate be placed in 60 DEG C and volatilize, obtain extractum, this extractum is placed in filtrate a and shakes up prepared one Agent, divides and sooner or later takes for twice.Every day takes potion, within 30 days, is a course for the treatment of.
After said medicine is combined by the present invention, its drug effect has synergism, the Chinese medicine composition of this kind of orally taken for curing renal carcinoma Thing can heat-clearing and toxic substances removing, the effect of inducing diuresis for treating stranguria syndrome, effective suppression growth of tumour cell and kill cancerous cell, have effective, The advantage of quick result.
Detailed description of the invention:
A kind of Chinese medicine composition treating renal carcinoma, the weight (g) of its each raw material components is: Radix Semiaquilegiae 60, Herba Bidentis Bipinnatae 60, Herba Sarcandrae 60, Rhizoma Smilacis Glabrae 60, Rhizoma Polygonati 30, Herba Hedyotidis Diffusae 30, Flos Lonicerae 15, Herba Verbenae 15, Radix Sophorae Tonkinensis 15.
Take component and weigh Radix Semiaquilegiae, Herba Bidentis Bipinnatae, Herba Sarcandrae, Rhizoma Smilacis Glabrae, Rhizoma Polygonati, Hedyotidis Diffusae, add 10 times amount water (V/W) 90 DEG C of heating, until concentrating is 600ml, is filtered, are obtained filtrate a;
Take Flos Lonicerae, Herba Verbenae, Radix Sophorae Tonkinensis again, with 10 times amount (V/W) 50% ethanol solution supersound extraction 1h(power 250W, Frequency 40kHz), filter, filtrate is volatilized solution in 60 DEG C, obtains extractum, this extractum is placed in filtrate a and shakes up prepared potion, Divide and sooner or later take for twice.Every day takes potion, within 30 days, is a course for the treatment of.
For proving that the present invention has good curative effect, enumerate model case as follows:
Case one:
Lee, man, 55 years old, within 2005, check, band blood, lower limbs edema, myasthenia of limbs in urine, deficient seriously, swollen seen from kidney portion CT Tumor, hospital is diagnosed as pernicious renal carcinoma.Patient abandons chemotherapeutic treatment.Use this patent medicine of the present invention, potion on the one, 1 course for the treatment of Rear pain relief, hemorrhage minimizing, appetite strengthen, and after 3 courses for the treatment of, CT display kidney portion tumor tumor body reduces, and other position does not finds Nascent tumor
Case two:
What certain, man, 60 years old, within 2002, check, band blood in urine, kidney portion CT visual tumors, hospital is diagnosed as renal carcinoma, and half a year is not in hospital Seeing and be obviously improved, here was treated later, took this patent medicine, and potion on the one, after taking 3 courses for the treatment of: body constitution strengthens, blood Urine, edema have been alleviated, and kidney portion tumor tumor body has no growth, and other position has no nascent tumor.
Case three:
Wu, man, 51 years old, the symptom such as difficult defecation, kidney portion CT visual tumors is diagnosed as renal carcinoma in early days, through January chemotherapy without substantially Taking a turn for the better, take this patent medicine, potion on the one, after taking 3 courses for the treatment of, symptom alleviates, and checks being clearly better after 3 courses for the treatment of, and Progressively take food, after continuing to take 3 courses for the treatment of, health gradually rehabilitation, it is possible to take care of oneself and work.
The respective situation of numerous patients is not enumerated by the present invention as space is limited, only makees with appeal example For explanation.
The present invention is as a example by traditional Chinese medical science renal carcinoma, through 35 example clinical observations.Selecting tcm diagnosis renal carcinoma is standard: band blood in urine, Lower limbs edema, myasthenia of limbs, deficient seriously, kidney portion CT visual tumors.As above symptom, can make a definite diagnosis.The medicine of the present invention is controlled Treating in renal carcinoma 35 example patient, effective 33 examples, effective 1 example, invalid 1 example, effective percentage reaches 97.14%.
Renal carcinoma efficacy evaluation:
Effective: body constitution strengthens, and the energeticallyest, hematuria, edema are substantially alleviated, CT display kidney portion tumor tumor body reduces, other position Do not find nascent tumor.
Effective: body constitution strengthens, hematuria, edema have been alleviated, and kidney portion tumor tumor body has no growth, and other position has no newborn Tumor.
Invalid: disease is unchanged, kidney portion tumor tumor body increases, or other position finds nascent tumor.

Claims (2)

1. the Chinese medicine composition treating renal carcinoma, it is characterised in that be made up of the raw material of following parts by weight: Radix Semiaquilegiae 60 parts, Herba Bidentis Bipinnatae 60 parts, Herba Sarcandrae 60 parts, Rhizoma Smilacis Glabrae 60 parts, Rhizoma Polygonati 30 parts, Herba Hedyotidis Diffusae 30 parts, Flos Lonicerae 15 parts, Herba Verbenae 15 Part, Radix Sophorae Tonkinensis 15 parts.
A kind of Chinese medicine composition treating renal carcinoma the most according to claim 1, it is characterised in that its preparation method is:
1) take Radix Semiaquilegiae, Herba Bidentis Bipinnatae, Herba Sarcandrae, Rhizoma Smilacis Glabrae each 60 parts and Rhizoma Polygonati, each 30 parts of Hedyotidis Diffusae, add 10 times amount volumes The water of weight ratio, in 90 DEG C of heating until concentrating 1/6 ~ 1/5 for original volume, filtering, obtaining filtrate a;
2) take Flos Lonicerae, Herba Verbenae, each 15 parts of Radix Sophorae Tonkinensis, surpass in power 250W, frequency 40kHz with 10 times of 50% ethanol solution Sound extracts 1h, filters, filtrate is placed in 60 DEG C and volatilizes, obtain extractum, be placed in filtrate a by this extractum and shake up and get final product.
CN201610879987.8A 2016-10-09 2016-10-09 Traditional Chinese medicine composition for treating renal carcinoma Pending CN106310045A (en)

Priority Applications (1)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1483423A (en) * 2002-09-19 2004-03-24 于天德 Traditional Chinese medicine for treating cancer and preparation method thereof
CN101675980A (en) * 2008-09-18 2010-03-24 天津市中宝制药有限公司 Traditional Chinese medicine composition for treating cancer
CN104127684A (en) * 2014-08-18 2014-11-05 杨全江 Traditional Chinese medicine compound preparation for treating cancers

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1483423A (en) * 2002-09-19 2004-03-24 于天德 Traditional Chinese medicine for treating cancer and preparation method thereof
CN101675980A (en) * 2008-09-18 2010-03-24 天津市中宝制药有限公司 Traditional Chinese medicine composition for treating cancer
CN104127684A (en) * 2014-08-18 2014-11-05 杨全江 Traditional Chinese medicine compound preparation for treating cancers

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
张代钊等著: "《张代钊治癌经验辑要》", 31 March 2001, 中国医药科技出版社 *
沈庆法: "肾癌术后的中医药治疗体会", 《上海中医药杂志》 *

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