CN106267304A - There is the biological cellulose gel film of Acidity of Aikalinity and medical dressing prepared therefrom - Google Patents
There is the biological cellulose gel film of Acidity of Aikalinity and medical dressing prepared therefrom Download PDFInfo
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- CN106267304A CN106267304A CN201510311014.XA CN201510311014A CN106267304A CN 106267304 A CN106267304 A CN 106267304A CN 201510311014 A CN201510311014 A CN 201510311014A CN 106267304 A CN106267304 A CN 106267304A
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- gel film
- cellulose gel
- acidity
- aikalinity
- biological cellulose
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Abstract
The present invention relates to a kind of biological cellulose gel film with Acidity of Aikalinity.It passes through unidirectional current electrolysis biological cellulose gel film, it is thus achieved that having the biological cellulose gel film of Acidity of Aikalinity, wherein during electrolysis, the surface of contact positive plate is acidic surface, and the surface of Contact cathod plate is basic surface.Acidic bio cellulose gel film and alkalescence biological cellulose gel film is obtained also by cutting.The described biological cellulose gel film with Acidity of Aikalinity and described acidic bio cellulose gel film can be prepared as medical dressing.The present invention need not to add antibiotics etc. can play good sterilization, antibacterial effect with regard to it, and safe to the human body nontoxic, and after use, it can be reduced to biological cellulose gel film common, biodegradable.
Description
Technical field
The present invention relates to the biological cellulose membrane of a kind of modification, in particular to having the biological cellulose gel film of Acidity of Aikalinity and medical dressing prepared therefrom.
Background technology
Dressing typically refer to cover skin ulcer, wound or materials of other infringements, it is used for treating sore spot or wound, and it is prepared often with gauze, binder as carrier with anticorrosion or antiseptic solution immersion.But, the carrier retentiveness such as gauze, binder and breathability are the highest, are unfavorable for wound healing；Meanwhile, anticorrosion or antiseptic solution easily remain, and improve the cost that medical material reclaims, and the sterilization antibacterial effect of itself is limited, and cost is the highest simultaneously.
Electrolysis water is the most universally acknowledged water the safest, state-of-the-art, and water is functionalized in electrolytic process.Acid water and alkaline water can be prepared by electrolysis simultaneously.Acid electrolyzed functional water can be with disinfection, and the acid-base balance that alkali ion water is able to maintain that in human body, remove free radical, activating cell, enhancing immunity, hypertension, hyperlipemia disease, diabetes, coronary heart disease, fatty liver etc. there are is good auxiliary therapeutic action.But, electrolysis water itself cannot commodity production, it is unstable, the most only will be reduced into common water after a few hours, and therefore it needs now-making-now-using, greatly limit its range of application.
Biology cellulose (Biocellulose) is obtained by biology cellulose producing strains metabolism.The production of biology cellulose is the liquid fermentation culture medium using natural or artificial preparation at present, inoculation biology cellulose producing strains, such as acetobacter xylinum, gluconate pyracetobacillus etc., after static culture, the liquid surface of liquid fermentation culture medium can produce gelatinous biological cellulose membrane, after solid-liquid separation, biological cellulose gel film product can be obtained through over cleaning, purification.This biological cellulose gel film has the moisture content more than 98%, and without association products such as lignin, pectin and hemicelluloses, has high-crystallinity and high polymerization degree.Additionally, it also has superfine space net structure, high water retention property, the most extensively apply in multiple fields.
Summary of the invention
Present invention firstly provides a kind of biological cellulose gel film with Acidity of Aikalinity, it is prepared by a method comprising the following steps:
(1)
Biological cellulose gel film soaks in slaine Barbiturates electrolyte solution；
(2)
Two electrode plate are connected to the both positive and negative polarity of DC source, and clamp the two sides of biological cellulose gel film by two electrode plate, be electrolysed；
Can obtain the biological cellulose gel film with Acidity of Aikalinity, wherein during electrolysis, the surface of contact positive plate is acidic surface, and the surface of Contact cathod plate is basic surface.
Slaine Barbiturates electrolyte in above-mentioned steps (1) is sodium chloride, potassium chloride, calcium chloride or their mixture.Preferably sodium chloride.
The concentration of the slaine Barbiturates electrolyte solution in above-mentioned steps (1) is 0.2-0.5%, and soak time is 0.5-3 hour.
The voltage between both positive and negative polarity in above-mentioned steps (2) is 8-12 volt.
Electrolysis time in above-mentioned steps (2) is 20-60min.
Before above-mentioned steps (1), preferably by partially dehydrated for biological cellulose gel film to water content be 50-70%.Dehydration preferably employs low temperature hot air drying or vacuum lyophilization.
In said method, it is also possible to include the biological cellulose gel film with Acidity of Aikalinity that will obtain, cut from centre along battery lead plate direction, obtain acidic bio cellulose gel film and alkalescence biological cellulose gel film.
Prepared by the most static shallow tray fermentation culture method of the biological cellulose gel film in said method, for producing strain and the culture medium the most particularly requirement of biology cellulose, as long as it can produce biological cellulose gel film.
In said method, slaine Barbiturates electrolyte is metal cation and the acid radical anion that dissolving in aqueous can form unordered movement, after additional DC voltage necessarily, cation can move to the direction of minus plate, at close minus plate, obtain electronics and be reduced, anion then can move to the direction of positive plate, is losing electronics at the positive plate and oxidized.The reaction occurred at two end electrodes plate is as follows:
Anode: 2Cl- → Cl2+2e-
Cl2+H2O
→ HCl+HClO
2H2O
→ O2+4H++4e-
Negative electrode: 2H2O+2e- → H2+2OH-
I.e. by above-mentioned reaction, transfer and the reaction of anions and canons is there occurs inside biological cellulose gel film, two faces making biological cellulose gel film have possessed different Acidity of Aikalinitys respectively, wherein during electrolysis, the surface of contact positive plate is acidic surface, and the surface of Contact cathod plate is basic surface.
The present invention further provides a kind of medical dressing, it is formed by the above-mentioned biological cellulose gel film preparation with Acidity of Aikalinity.
The present invention further provides a kind of medical dressing, it is prepared from by the above-mentioned acidic bio cellulose gel film through cutting.
In above-mentioned medical dressing, whether there is the acidic bio cellulose gel film after the biological cellulose gel film of Acidity of Aikalinity still cuts, its on the packaging or in packaging all with indicating or contacting wound or the open sore part with acid time explanation shows to use.
The invention provides a kind of two sides and there is the biological cellulose membrane product of different Acidity of Aikalinity, using biological cellulose gel film as carrier, electrolyte is allowed to be electrolysed wherein, it is obtained in that two sides has different Acidity of Aikalinity, use acidic surface as dressing, need not add antibiotics etc. and can play the good effect killing the microorganism such as antibacterial, fungus with regard to it, and it is safe to the human body nontoxic, after use, it can be reduced to biological cellulose gel film common, biodegradable, does not has any chemical residual.Therefore, the present invention can reduce the production of medical dressing, cost recovery, reduces environmental pollution, has good economical, societal benefits.In addition; after electrolysis, each ion, electronics are present in the space net structure of biological cellulose gel, and the fiber of biological cellulose gel can hinder it to move, and biological cellulose gel can completely cut off external environment; it is played a protective role, therefore, it is possible to effectively extend the time that its activity keeps.
Detailed description of the invention
Below in conjunction with detailed description of the invention and contrast experiment, the present invention is further illustrated, but implementation is understood not to limitation of the present invention in detail below.Various changes that those of ordinary skill in the art can make the most apparently and change, it should the most within the scope of the present invention.
Embodiment 1: there is the preparation of the biological cellulose gel film of Acidity of Aikalinity
After taking artificial preparation culture medium inoculated gluconate pyracetobacillus, the biological cellulose gel film of preparation in 7 days is cultivated at 30 DEG C, repeatedly clean with after purification through sig water and deionized water, be 60% with 50 DEG C of hot air dryings to water content, then soak 3 hours in the sodium chloride solution that concentration is 0.2%；Two electrode plate are connected to the both positive and negative polarity of DC source, and the voltage between both positive and negative polarity is 10 volts, and clamps the two sides of biological cellulose gel film by two electrode plate, is electrolysed 40min, prepares the biological cellulose gel film with Acidity of Aikalinity.
Embodiment 2: the preparation of acidic bio cellulose gel film
After taking artificial preparation culture medium inoculated acetobacter xylinum, the biological cellulose gel film of preparation in 9 days is cultivated at 28 DEG C, repeatedly cleaning with after purification through sig water and deionized water, vacuum lyophilization to water content is 65%, then soaks 1 hour in the sodium chloride solution that concentration is 0.4%；Two electrode plate are connected to the both positive and negative polarity of DC source, voltage between both positive and negative polarity is 12 volts, and the two sides of biological cellulose gel film is clamped by two electrode plate, electrolysis 50min, prepare the biological cellulose gel film with Acidity of Aikalinity, then cutting along battery lead plate direction from centre, that sheet wherein contacting positive plate is acidic bio cellulose gel film.
Embodiment 3: the preparation of medical dressing
In the biological cellulose gel film with Acidity of Aikalinity prepared in Example 1 or embodiment 2, the acidic bio cellulose gel film of preparation is directly as medical dressing, use colored plastic material is vacuum-packed, and has surface contact wound or the open sore part indicating or illustrating to show to make to contact with positive plate during electrolysis when using on the packaging.
Embodiment described above is only to be described the preferred embodiment of the present invention; not the scope of the present invention is defined; on the premise of designing spirit without departing from the present invention; various deformation that technical scheme is made by this area ordinary skill technical staff and improvement, all should fall in the protection domain that claims of the present invention determines.
Claims (10)
1. a biological cellulose gel film with Acidity of Aikalinity, it is characterised in that: it is prepared by a method comprising the following steps:
(1) biological cellulose gel film soaks in slaine Barbiturates electrolyte solution；
(2) two electrode plate are connected to the both positive and negative polarity of DC source, and clamp the two sides of biological cellulose gel film by two electrode plate, be electrolysed；
Can obtain the biological cellulose gel film with Acidity of Aikalinity, wherein during electrolysis, the surface of contact positive plate is acidic surface, and the surface of Contact cathod plate is basic surface.
The biological cellulose gel film with Acidity of Aikalinity the most according to claim 1, it is characterised in that: the slaine Barbiturates electrolyte in described step (1) is sodium chloride, potassium chloride, calcium chloride or their mixture.
The biological cellulose gel film with Acidity of Aikalinity the most according to claim 2, it is characterised in that: the slaine Barbiturates electrolyte in described step (1) is sodium chloride.
The biological cellulose gel film with Acidity of Aikalinity the most according to claim 1, it is characterised in that: the concentration of the slaine Barbiturates electrolyte solution in described step (1) is 0.2-0.5%, and soak time is 0.5-3 hour.
The biological cellulose gel film with Acidity of Aikalinity the most according to claim 1, it is characterised in that: the voltage between both positive and negative polarity in described step (2) is 8-12 volt, and electrolysis time is 20-60min.
The biological cellulose gel film with Acidity of Aikalinity the most according to claim 1, it is characterised in that: before described step (1), by biological cellulose gel film dehydration to water content be 50-70%.
The biological cellulose gel film with Acidity of Aikalinity the most according to claim 6, it is characterised in that: dehydration uses low temperature hot air drying or vacuum lyophilization.
The biological cellulose gel film with Acidity of Aikalinity the most according to claim 1, it is characterized in that: in described method, also include the biological cellulose gel film with Acidity of Aikalinity that will obtain, cut from centre along battery lead plate direction, obtain acidic bio cellulose gel film and alkalescence biological cellulose gel film.
9. a medical dressing, it is characterised in that: it is prepared from by the biological cellulose gel film with Acidity of Aikalinity described in any one of one of claim 1-7 or the acidic bio cellulose gel film described in claim 8.
Medical dressing the most according to claim 9, it is characterised in that: use lighttight packaging material to be vacuum-packed, and on the packaging or have surface contact wound or the open sore part indicating or illustrating to show to make to contact with positive plate during electrolysis when using in packaging.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201510311014.XA CN106267304B (en) | 2015-06-09 | 2015-06-09 | Biological cellulose gel film and medical dressing prepared therefrom with acid-base property |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510311014.XA CN106267304B (en) | 2015-06-09 | 2015-06-09 | Biological cellulose gel film and medical dressing prepared therefrom with acid-base property |
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| CN106267304A true CN106267304A (en) | 2017-01-04 |
| CN106267304B CN106267304B (en) | 2019-10-18 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102252878A (en) * | 2011-03-20 | 2011-11-23 | 北京理工大学 | Off-Gel free flow electrophoresis coupling chip and making method thereof |
| CN103134843A (en) * | 2007-08-27 | 2013-06-05 | 技术研究及发展基金有限公司 | PH gradients controlled by electrolysis and their use in isoelectric focusing |
| US20150118324A1 (en) * | 2011-03-18 | 2015-04-30 | Puricore, Inc. | Stabilized hypohalous acid solutions |
-
2015
- 2015-06-09 CN CN201510311014.XA patent/CN106267304B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103134843A (en) * | 2007-08-27 | 2013-06-05 | 技术研究及发展基金有限公司 | PH gradients controlled by electrolysis and their use in isoelectric focusing |
| US20150118324A1 (en) * | 2011-03-18 | 2015-04-30 | Puricore, Inc. | Stabilized hypohalous acid solutions |
| CN102252878A (en) * | 2011-03-20 | 2011-11-23 | 北京理工大学 | Off-Gel free flow electrophoresis coupling chip and making method thereof |
Non-Patent Citations (1)
| Title |
|---|
| SOON HONC YUK ET AL.: ""Electric-Current-Sensitive Polymers. Reversible Bending of Rod-Shaped Acrylamide Gel in NaCl Solution"", 《JOURNAL OF POLYMER SCIENCE: PART B POLYMER PHYSICS》 * |
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