CN106267077A - A kind of Chinese medicine composition treating adenomesenteritis and preparation thereof and application - Google Patents
A kind of Chinese medicine composition treating adenomesenteritis and preparation thereof and application Download PDFInfo
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- CN106267077A CN106267077A CN201610768890.XA CN201610768890A CN106267077A CN 106267077 A CN106267077 A CN 106267077A CN 201610768890 A CN201610768890 A CN 201610768890A CN 106267077 A CN106267077 A CN 106267077A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/268—Asarum (wild ginger)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
Abstract
The invention discloses a kind of Chinese medicine composition treating adenomesenteritis and preparation thereof and application, described Chinese medicine composition includes the crude drug of following weight portion: Fructus Mume 50～150 parts, Rhizoma Corydalis 100～200 parts, Radix Curcumae 100～200 parts, Radix Aconiti Lateralis Preparata 20～40 parts, Ramulus Cinnamomi 50～150 parts, Cortex Phellodendri 50～150 parts, Rhizoma Coptidis 20～40 parts, Radix Angelicae Sinensis 50～150 parts, Fructus Zanthoxyli 40～60 parts, Rhizoma Zingiberis 40～60 parts, Herba Asari 15～25 parts, Fructus Toosendan 100～200 parts, Semen Arecae 100～200 parts.Scientific compatibility of the present invention, the mutual synergism of each component, anti-inflammatory analgetic, antibacterial detumescence, expelling wind and cold, heat-clearing and toxic substances removing, YANG invigorating activating QI, treatment adenomesenteritis is had splendid curative effect, cure rate is high, and takes safety.It addition, the Chinese medicine composition of the present invention can be made into multiple dosage form, the curative effect of capsule it is further preferred that, the demand of different patient can be met.Additionally the curative effect through clinical discovery traditional Chinese medicine composition for treating of the present invention ascariasis is the most excellent.
Description
Technical field
The present invention relates to tcm field, particularly relate to a kind of Chinese medicine composition treating adenomesenteritis and system thereof
Agent and application.
Background technology
Mesentery is made up of with the visceral peritoneum parietal layer, mainly has mesostenium and mesocolon, in addition with mesoappendix and
Ovary, mesosalpinx etc..Mesostenium is to connect jejunum, ileum and the peritoneum of posterior abdominal wall, in sector, is attached to posterior wall of abdomen
Part is root of mesentery, the small intestinal edge length 6～7m of mesentery, inside have on mesentery artery and vein and branch thereof, lacteal vessel, plexus nervorum and
Lymph node etc..Mesentery has abundant lymph to be distributed, and lymphatic vessel comes from the center in intestinal mucosa blood capillary clump or intestinal villi
Lacteal vessel, goes together with mesenteric vein, drains into mesentery root lymph node or paraaortic lymph nodes, then through cisterna chyli,
Thoracic duct and enter blood circulation.Virus or antibacterial infect when involving mesenteric lymph node, can produce adenomesenteritis.Existing
In technology, mainly with the Western medicine such as infection, antiviral as main treatment, its cure rate is low, and side effect is big, and cures the symptoms, not the disease.
Summary of the invention
In view of this, the invention provides a kind of Chinese medicine composition treating adenomesenteritis and preparation thereof and answer
With, described Chinese medicine composition has splendid curative effect to treatment adenomesenteritis, and cure rate is high, and takes safety.
The technological means that the present invention uses is as follows: a kind of Chinese medicine composition treating adenomesenteritis, including following
The crude drug of weight portion: Fructus Mume 50～150 parts, Rhizoma Corydalis 100～200 parts, Radix Curcumae 100～200 parts, Radix Aconiti Lateralis Preparata 20～40 parts, osmanthus
50～150 parts of branch, Cortex Phellodendri 50～150 parts, Rhizoma Coptidis 20～40 parts, Radix Angelicae Sinensis 50～150 parts, Fructus Zanthoxyli 40～60 parts, Rhizoma Zingiberis 40～60
Part, Herba Asari 15～25 parts, Fructus Toosendan 100～200 parts, Semen Arecae 100～200 parts.
Preferably, the Chinese medicine composition of described treatment adenomesenteritis, including the crude drug of following weight portion: Fructus Mume
80～120 parts, Rhizoma Corydalis 120～180 parts, Radix Curcumae 120～180 parts, Radix Aconiti Lateralis Preparata 25～35 parts, Ramulus Cinnamomi 80～120 parts, Cortex Phellodendri 80～
120 parts, Rhizoma Coptidis 25～35 parts, Radix Angelicae Sinensis 80～120 parts, Fructus Zanthoxyli 45～55 parts, Rhizoma Zingiberis 45～55 parts, Herba Asari 18～22 parts, river
Son 120～180 parts, Semen Arecae 120～180 parts.
Preferably, the Chinese medicine composition of described treatment adenomesenteritis, including the crude drug of following weight portion: Fructus Mume
100 parts, Rhizoma Corydalis 150 parts, Radix Curcumae 150 parts, Radix Aconiti Lateralis Preparata 30 parts, Ramulus Cinnamomi 100 parts, Cortex Phellodendri 100 parts, Rhizoma Coptidis 30 parts, Radix Angelicae Sinensis 100 parts,
Fructus Zanthoxyli 50 parts, Rhizoma Zingiberis 50 parts, Herba Asari 20 parts, Fructus Toosendan 150 parts, Semen Arecae 150 parts.
Present invention also offers a kind of Chinese medicinal composition preparation treating adenomesenteritis, comprise what the present invention provided
The Chinese medicine composition of the treatment adenomesenteritis described in any one, the Chinese medicine composition of described treatment adenomesenteritis
Preparation is the one of granule, oral liquid, pill, capsule.
Present invention also offers the Chinese medicine composition of described treatment adenomesenteritis treatment adenomesenteritis,
Application in ascariasis.
Beneficial effect: a kind of Chinese medicine composition treating adenomesenteritis that the invention provides, described Chinese drug-treated group
In compound Fructus Mume astringe the lung, astringing intestine to stop diarrhea, relieving colic caused by ascaris, Rhizoma Corydalis is invigorated blood circulation, circulation of qi promoting, pain relieving, Radix Curcumae promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, profit
Gallbladder jaundice eliminating, Radix Aconiti Lateralis Preparata mends supporing yang, the dispelling cold and removing dampness of fire, Ramulus Cinnamomi promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins, and Cortex Phellodendri heat clearing and damp drying, rushes down
Fire except steaming, removing toxic substances, Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication, Chinese angelica blood supplementing is invigorated blood circulation, pain relieving, loosening bowel to relieve constipation, Fructus Zanthoxyli warming spleen and stomach for dispelling cold, only
Bitterly, dampness, parasite killing, Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG promote blood circulation, Herba Asari relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, Fructus Toosendan soothing liver-QI circulation of qi promoting, pain relieving,
Dehumidifying heat, anthelmintic, Semen Arecae parasite killing, removing food stagnancy, circulation of qi promoting, preventing the attack (or recurrence) of malaria.Scientific compatibility, the mutual synergism of each component, anti-inflammatory analgetic, antibacterial
Detumescence, expelling wind and cold, heat-clearing and toxic substances removing, YANG invigorating activating QI, have splendid curative effect to treatment adenomesenteritis, for 1～3 years old
The cure rate of pediatric patient be up to 86%, total effective rate is up to 100%, be up to 84% for the cure rate of more than 4 years old patient,
Total effective rate is up to 98%.And take safety.It addition, the Chinese medicine composition of the present invention can be made into multiple dosage form, to treatment intestinal system
Film lymphadenitis is respectively provided with good effect, the curative effect of capsule it is further preferred that, the demand of different patient can be met.Additionally send out through clinic
The curative effect of existing traditional Chinese medicine composition for treating ascariasis of the present invention is the most excellent.
Detailed description of the invention
Introduce the nature and flavor of primary raw material medicine based on the following " Chinese Pharmacopoeia ", " Chinese medicine voluminous dictionary " and " China's draft ", return
The basic conditions such as warp, function and application.
Fructus Mume: sour, puckery is flat.Return liver, spleen, lung, large intestine channel.Astringe the lung, astringing intestine to stop diarrhea, promote the production of body fluid, relieving colic caused by ascaris.For chronic cough of deficiency lung, chronic diarrhea
Chronic dysentery, deficiency-heat quenches one's thirst, ascariasis of biliary tract vomiting stomachache.
Rhizoma Corydalis: pungent, bitter, temperature.Return liver, spleen channel.Invigorate blood circulation, circulation of qi promoting, pain relieving.For the breast side of body, epigastric pain, obstruction of qi in the chest and cardialgia, warp
Close dysmenorrhea, postpartum stagnation, tumbling and swelling.
Radix Curcumae: pungent, bitter, cold.Return liver, the heart, lung meridian.Promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, clear away heart-fire removing heat from blood, promoting the function of the gallbladder to alleviate jaundice.For breast
Side of body twinge, obstruction of qi in the chest and cardialgia, amenorrhea dysmenorrhea, distending pain of the breast, calentura coma, epilepsy goes mad, and heat in blood tells nosebleed, jaundice dark coloured urine.
Radix Aconiti Lateralis Preparata: Xin Gan, heat, poisonous.Enter heart channel, spleen channel, kidney channel.Recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, dispelling cold and removing dampness.Control the moon
Containing refusing yang, loss of YANG due to profuse perspiration, vomiting and diarrhea is fainted inverse, trusted subordinate's cold type of pain, the splenic diarrhea cold-dysentery, tinea pedis edema children's's intermittent infantile convulsion, anemofrigid-damp arthralgia, arrests
Contraction, sexual impotence, cold womb is cloudy, the leakage of cellulitis skin ulcer and the disease of all chronic diseaseses.
Ramulus Cinnamomi: acrid, sweet, warm.GUIXIN, lung, bladder warp.Diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For
Anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Cortex Phellodendri: bitter, cold.Return kidney, bladder warp.Heat clearing and damp drying, pathogenic fire purging is except steaming, detoxification sore treatment.For damp-heat dysentery, jaundice is urinated
Red, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, tinea pedis flaccidity is preesed, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema eczema.
Rhizoma Coptidis: bitter, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomit
Tell acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, palpitation and uneasiness, heat in blood tells nosebleed, conjunctival congestion, toothache, quenches one's thirst,
Carbuncle treats skin ulcer；External treatment eczema, eczema, auditory meatus is suppurated.
Radix Angelicae Sinensis: sweet, acrid, warm.Return liver, the heart, spleen channel.Replenishing and activating blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy
Dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.
Fructus Zanthoxyli: pungent, temperature, slightly poisonous.Enter spleen, stomach, kidney channel.Warming spleen and stomach for dispelling cold, pain relieving, dampness, parasite killing.(1) stomach abdomen cold type of pain is controlled,
Vomiting, dysentery, anemofrigid-damp arthralgia, lung cold cough with asthma, colic, ascariasis.(2) enterobiasis is controlled, decocting liquid coloclysis；Pudendal pruritus leukorrhagia, chilblain is decocted
Washing；Toothache, rinsing the mouth decocted by vinegar.
Rhizoma Zingiberis: pungent, heat.Return spleen, stomach, kidney, the heart, lung meridian.Warming spleen and stomach for dispelling cold, recuperating depleted YANG promotes blood circulation, warming the lung to resolve fluid-retention.Cold for gastral cavity abdomen
Bitterly, vomiting is had loose bowels, cold extremities faint pulse, and cold fluid-retention is breathed with cough.
Herba Asari: pungent, temperature.GUIXIN, lung, kidney channel.Relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, sensible, warming the lung to resolve fluid-retention.For anemofrigid cold,
Headache, toothache, watery nasal discharge of having a stuffy nose, allergic rhinitis, nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.
Fructus Toosendan: bitter, cold.Enter liver, stomach, small intestine meridian.Soothing liver-QI promoting the circulation of QI to relieve pain, dehumidifying heat, anthelmintic.For the breast side of body, gastral cavity abdominal distention
Bitterly, colic, abdominal pain due to worm stagnation.
Semen Arecae: bitter, pungent, temperature.Return stomach, large intestine channel.Parasite killing, removing food stagnancy, circulation of qi promoting, diuretic, preventing the attack (or recurrence) of malaria.For taeniasis, ascariasis,
Fasciolopsiasis buski, abdominal pain due to worm stagnation, stagnant dysentery, tenesmus, edema tinea pedis, malaria.
Being described the specific embodiment of the present invention below, illustrated embodiment is served only for explaining the present invention, is not intended to
Limit the scope of the present invention.
Embodiment 1
A kind of Chinese medicine composition treating adenomesenteritis, including the crude drug of following weight:
Fructus Mume 5g, Rhizoma Corydalis 10g, Radix Curcumae 10g, Radix Aconiti Lateralis Preparata 2g, Ramulus Cinnamomi 5g, Cortex Phellodendri 5g, Rhizoma Coptidis 2g, Radix Angelicae Sinensis 5g, Fructus Zanthoxyli 4g, dry
Rhizoma Zingiberis Recens 4g, Herba Asari 1.5g, Fructus Toosendan 10g, Semen Arecae 10g.
Above-mentioned raw materials medicine soak by water according to a conventional method.
Embodiment 2
A kind of Chinese medicine composition treating adenomesenteritis, including the crude drug of following weight:
Fructus Mume 15g, Rhizoma Corydalis 20g, Radix Curcumae 20g, Radix Aconiti Lateralis Preparata 4g, Ramulus Cinnamomi 15g, Cortex Phellodendri 15g, Rhizoma Coptidis 4g, Radix Angelicae Sinensis 15g, Fructus Zanthoxyli
6g, Rhizoma Zingiberis 6g, Herba Asari 2.5g, Fructus Toosendan 20g, Semen Arecae 20g.
Above-mentioned raw materials medicine soak by water according to a conventional method.
Embodiment 3
A kind of Chinese medicine composition treating adenomesenteritis, including the crude drug of following weight:
Fructus Mume 8g, Rhizoma Corydalis 12g, Radix Curcumae 12g, Radix Aconiti Lateralis Preparata 2.5g, Ramulus Cinnamomi 8g, Cortex Phellodendri 8g, Rhizoma Coptidis 2.5g, Radix Angelicae Sinensis 8g, Fructus Zanthoxyli
4.5g, Rhizoma Zingiberis 4.5g, Herba Asari 1.8g, Fructus Toosendan 12g, Semen Arecae 12g.
Above-mentioned raw materials medicine soak by water according to a conventional method.
Embodiment 4
A kind of Chinese medicine composition treating adenomesenteritis, including the crude drug of following weight:
Fructus Mume 12g, Rhizoma Corydalis 18g, Radix Curcumae 18g, Radix Aconiti Lateralis Preparata 3.5g, Ramulus Cinnamomi 12g, Cortex Phellodendri 12g, Rhizoma Coptidis 3.5g, Radix Angelicae Sinensis 12g,
Fructus Zanthoxyli 5.5g, Rhizoma Zingiberis 5.5g, Herba Asari 2.2g, Fructus Toosendan 18g, Semen Arecae 18g.
Above-mentioned raw materials medicine soak by water according to a conventional method.
Embodiment 5
A kind of Chinese medicine composition treating adenomesenteritis, including the crude drug of following weight:
Fructus Mume 10g, Rhizoma Corydalis 15g, Radix Curcumae 10g, Radix Aconiti Lateralis Preparata 2g, Ramulus Cinnamomi 10g, Cortex Phellodendri 10g, Rhizoma Coptidis 3g, Radix Angelicae Sinensis 10g, Fructus Zanthoxyli
5g, Rhizoma Zingiberis 5g, Herba Asari 2g, Fructus Toosendan 10g, Semen Arecae 10g.
Above-mentioned raw materials medicine soak by water according to a conventional method.
Embodiment 6
A kind of Chinese medicine composition treating adenomesenteritis, including the crude drug of following weight:
Fructus Mume 10g, Rhizoma Corydalis 15g, Radix Curcumae 20g, Radix Aconiti Lateralis Preparata 4g, Ramulus Cinnamomi 10g, Cortex Phellodendri 10g, Rhizoma Coptidis 3g, Radix Angelicae Sinensis 10g, Fructus Zanthoxyli
5g, Rhizoma Zingiberis 5g, Herba Asari 2g, Fructus Toosendan 20g, Semen Arecae 20g.
Above-mentioned raw materials medicine soak by water according to a conventional method.
Embodiment 7
A kind of Chinese medicine composition treating adenomesenteritis, including the crude drug of following weight:
Fructus Mume 10g, Rhizoma Corydalis 15g, Radix Curcumae 15g, Radix Aconiti Lateralis Preparata 3g, Ramulus Cinnamomi 10g, Cortex Phellodendri 10g, Rhizoma Coptidis 3g, Radix Angelicae Sinensis 10g, Fructus Zanthoxyli
5g, Rhizoma Zingiberis 5g, Herba Asari 2g, Fructus Toosendan 15g, Semen Arecae 15g.
Above-mentioned raw materials medicine soak by water according to a conventional method.
Embodiment 8
A kind of Chinese medicine composition treating adenomesenteritis, including the crude drug of following weight:
Fructus Mume 5g, Rhizoma Corydalis 7.5g, Radix Curcumae 7.5g, Radix Aconiti Lateralis Preparata 1.5g, Ramulus Cinnamomi 5g, Cortex Phellodendri 5g, Rhizoma Coptidis 1.5g, Radix Angelicae Sinensis 5g, river
Green pepper 2.5g, Rhizoma Zingiberis 2.5g, Herba Asari 1g, Fructus Toosendan 7.5g, Semen Arecae 7.5g.
Above-mentioned raw materials medicine soak by water according to a conventional method.
A kind of traditional Chinese medicine composition for treating adenomesenteritis treating adenomesenteritis of the present invention has significantly
Effect, in order to verify its beneficial effect, by each of a kind of Chinese medicine composition treating adenomesenteritis of the present invention
Embodiment is tested, and test method and result are as follows:
One, clinical data
1, basic document: collect adenomesenteritis patient 400 example altogether；Test group 1～test group 8, often organize 50 examples.
Test group 1: this organizes 50 examples, age 4～15 years old 40 example, 15～40 years old 10 example.
Test group 2: this organizes 50 examples, age 4～15 years old 40 example, 15～40 years old 10 example.
Test group 3: this organizes 50 examples, age 4～15 years old 40 example, 15～40 years old 10 example.
Test group 4: this organizes 50 examples, age 4～15 years old 40 example, 15～40 years old 10 example.
Test group 5: this organizes 50 examples, age 4～15 years old 40 example, 15～40 years old 10 example.
Test group 6: this organizes 50 examples, age 4～15 years old 40 example, 15～40 years old 10 example.
Test group 7: this organizes 50 examples, age 4～15 years old 40 example, 15～40 years old 10 example.
Test group 8: this organizes 50 examples, age 1～3 years old.
2, clinical manifestation: often at upper respiratory tract infection symptoms such as premorbid 1～2 days sense general malaises, pharyngalgia, heatings.Continue
And stomachache occurs, it is positioned at around left lower quadrant and umbilicus, often in paroxysmal, such as coil buckling sample more.Again occur after feed that pain can be vomitted
Tell food.Having a medical check-up and see flush, lip is pale, pharyngeal congestion, and abdominal tenderness is many is diagonal distribution by bottom right to upper left, but with
Right Lower Abdomen is substantially, many without muscle tonus and rebound tenderness.
3, Excluded cases: other diseases such as appendicitis, tuberculous lymphadenitis.
Two, Therapeutic Method and the course for the treatment of
Test group 1: a kind of Chinese medicine composition (embodiment 1) treating adenomesenteritis of the present invention, day 1 dose, water
Decocting point 2 decoction being taken warmly use, 7 days was 1 course for the treatment of, took 1～3 course for the treatment of.
Test group 2: a kind of Chinese medicine composition (embodiment 2) treating adenomesenteritis of the present invention, day 1 dose, water
Decocting point 2 decoction being taken warmly use, 7 days was 1 course for the treatment of, took 1～3 course for the treatment of.
Test group 3: a kind of Chinese medicine composition (embodiment 3) treating adenomesenteritis of the present invention, day 1 dose, water
Decocting point 2 decoction being taken warmly use, 7 days was 1 course for the treatment of, took 1～3 course for the treatment of.
Test group 4: a kind of Chinese medicine composition (embodiment 4) treating adenomesenteritis of the present invention, day 1 dose, water
Decocting point 2 decoction being taken warmly use, 7 days was 1 course for the treatment of, took 1～3 course for the treatment of.
Test group 5: a kind of Chinese medicine composition (embodiment 5) treating adenomesenteritis of the present invention, day 1 dose, water
Decocting point 2 decoction being taken warmly use, 7 days was 1 course for the treatment of, took 1～3 course for the treatment of.
Test group 6: a kind of Chinese medicine composition (embodiment 6) treating adenomesenteritis of the present invention, day 1 dose, water
Decocting point 2 decoction being taken warmly use, 7 days was 1 course for the treatment of, took 1～3 course for the treatment of.
Test group 7: a kind of Chinese medicine composition (embodiment 7) treating adenomesenteritis of the present invention, day 1 dose, water
Decocting point 2 decoction being taken warmly use, 7 days was 1 course for the treatment of, took 1～3 course for the treatment of.
Test group 8: a kind of Chinese medicine composition (embodiment 8) treating adenomesenteritis of the present invention, day 1 dose, water
Decoct point 2 decoction being taken warmly use, within 3 days, be 1 course for the treatment of.Take 1～3 course for the treatment of.
Three, therapeutic outcome
Curative effect judging standard: cure: disease of suffering from abdominal pain and hold concurrently disappears, body temperature is normal, and abdominal part color ultrasound display mesenteric lymph node is extensive
Multiple normal.Effective: the symptoms such as stomachache alleviate or disappear, body temperature is normal, and abdominal part color ultrasound display mesenteric lymph node reduces.Invalid:
Colic symptoms is improved little, and abdominal part color ultrasound display mesentery film lymph node is unchanged.Total effective=healing+effectively.Total effective rate
=(cure+effectively)/total number of cases.
1, the case number of cases of the therapeutic effect of each test group is as shown in table 1 below:
| Case load (example) | Recovery from illness (example) | Effectively (example) | Invalid (example) | Total effective (example) | |
| Test group 1 | 50 | 36 | 8 | 6 | 44 |
| Test group 2 | 50 | 35 | 9 | 6 | 44 |
| Test group 3 | 50 | 38 | 7 | 5 | 45 |
| Test group 4 | 50 | 39 | 7 | 4 | 46 |
| Test group 5 | 50 | 41 | 6 | 3 | 47 |
| Test group 6 | 50 | 40 | 8 | 2 | 48 |
| Test group 7 | 50 | 42 | 7 | 1 | 49 |
| Test group 8 | 50 | 43 | 7 | 0 | 50 |
2, the case percent of the therapeutic effect of each test group is as shown in table 2 below:
| Recovery from illness (%) | Effectively (%) | Invalid (%) | Total effective (%) | |
| Test group 1 | 72 | 16 | 12 | 88 |
| Test group 2 | 70 | 18 | 12 | 88 |
| Test group 3 | 76 | 14 | 10 | 90 |
| Test group 4 | 78 | 14 | 8 | 92 |
| Test group 5 | 82 | 12 | 6 | 94 |
| Test group 6 | 80 | 16 | 4 | 96 |
| Test group 7 | 84 | 14 | 2 | 98 |
| Test group 8 | 86 | 14 | 0 | 100 |
3, model case
1. money so-and-so, man 5 years old, during patient assessment, the head of a family tells after cause on the 1st suffers from sense, with stomachache, in paroxysmal, with the right side
The light tenderness of lower abdomen is main, without rebound tenderness, through ultrasound diagnosis, is diagnosed as adenomesenteritis.Take Drug therapy of the present invention 1
After the course for the treatment of, colic symptoms takes a turn for the better, and fully recovers after taking again 1 course for the treatment of, follows up a case by regular visits to drug withdrawal over 3 months without recurrence.
2. Zhang, female 7 years old, during patient assessment, the head of a family tells after cause on the 2nd suffers from sense, Right Lower Abdomen pain occurs, in paroxysm
Property, abdomen is soft, has light tenderness, without rebound tenderness, through ultrasound diagnosis, is diagnosed as adenomesenteritis.Take Drug therapy 1 of the present invention
After the individual course for the treatment of, colic symptoms takes a turn for the better, and fully recovers after taking again 1 course for the treatment of, follows up a case by regular visits to drug withdrawal over the past half year without recurrence.
3. Lin, man 14 years old, during patient assessment, the head of a family tells after cause on the 2nd suffers from sense, Right Lower Abdomen and umbilicus week pain occurs, in
Paroxysmal, such as coil buckling sample, abdomen is soft, has light tenderness, without rebound tenderness, through ultrasound diagnosis, is diagnosed as adenomesenteritis.Take this
After 1 course for the treatment of of invention Drug therapy, colic symptoms takes a turn for the better, and fully recovers after taking again 1 course for the treatment of, continues to take 1 course for the treatment of afterwards and consolidates
Curative effect, follows up a case by regular visits to drug withdrawal over the past half year without recurrence.
Four, untoward reaction is observed
In Ureteral Calculus case, find no untoward reaction patient, show that the one of the present invention treats mesenteric lymph
The Chinese medicine composition of knot inflammation is safe and reliable.
Being shown by above-mentioned clinical trial, Chinese medicine composition of the present invention is to treatment adenomesenteritis patient tool
There is splendid curative effect, be up to 86% for the cure rate of 1～the pediatric patient of 3 years old, total effective rate is up to 100%, within more than 4 years old, suffer from
The cure rate of person is up to 84%, total effective rate is up to 98%.Wherein, test group 3～4 is better than the therapeutic effect of test group 1～2,
Show that embodiment 3～4 compares embodiment 1～2 more preferable to the effect for the treatment of adenomesenteritis；And test group 7 is than test group 3
～the therapeutic effect of 4 is more preferable, it is known that compare embodiment 1～4, embodiment 7 is optimal to the effect for the treatment of adenomesenteritis
, the weight ratio of each component of embodiment 7 is most preferred so that each component synergism is optimal.It addition, test group 7 is than test
Group 5～6 therapeutic effect good, show that embodiment 7 compares each component synergism of embodiment 5～6 more preferably, show component Radix Curcumae,
Radix Aconiti Lateralis Preparata, river, Semen Arecae have large effect to curative effect；Test group 5 is better than the therapeutic effect of test group 1, i.e. embodiment 5 is compared
More preferably, test group 6 is better than the therapeutic effect of test group 2 for the curative effect of embodiment 1, i.e. embodiment 6 compares the curative effect of embodiment 2 more
Good, show that component Fructus Mume, Rhizoma Corydalis, Ramulus Cinnamomi, Cortex Phellodendri, Rhizoma Coptidis, Radix Angelicae Sinensis, Fructus Zanthoxyli, Rhizoma Zingiberis, Herba Asari have large effect to curative effect.Separately
Outward, the relative decrement of embodiment 8, special supply young children takes, therapeutic effect it is further preferred that.To sum up, embodiment 7 to treatment 4 years old with
The curative effect of dorsal mesentery lymphadenitis patient is more excellent, and embodiment 8 has extraordinary treatment to the patient for the treatment of less than 4 years old simultaneously
Effect.A kind of Chinese medicine composition treating adenomesenteritis that the present invention provides is described, the mutual synergism of each component, to controlling
Treat adenomesenteritis and there is significant curative effect, and safety is high, has no side effect.
In a further embodiment, a kind of Chinese medicine composition of adenomesenteritis for the treatment of of the present invention is by routine side
Method is prepared as granule, oral liquid, pill, capsule, and treatment adenomesenteritis is respectively provided with good effect, especially capsule
The curative effect of agent is more preferably.
Additionally also by clinical case, inventor finds that the Chinese medicine composition of described treatment adenomesenteritis is to treatment
Ascariasis also has good effect.Ascariasis is owing to ascarid parasitizes intestinal, and with paroxysm umbilicus pain abdomen pain, recurrent exerbation is
The parasitic disease of main clinical manifestation.Collect 78 example ascariasis patients altogether.Its diagnosis basis, administrated method, the course for the treatment of, treatment standard
And clinical effectiveness is as follows:
Diagnosis basis: 1. paroxysmal umbilicus week stomachache, shows effect the most suddenly, logical without fixed place, can spontaneous remission.2. heating can be had to cough
Coughing or asthma, sputum mixed with blood, there is rubella wheal group in skin, sleeps to plant and grinds one's teeth in sleep, sialorrhea, rhinocnesmus.Sick emaciation and sallow complexion for a long time, look irritated,
Reject ascarid or discharge ascarid.3. blue class seen from sclera, there is white pityriasis simplex, has the granular point of white chestnut, refer to inside lip in face
First piebaldism.The accessible streak ascarid group of abdominal part, time poly-time dissipate.4. unhygienic diet and vomiting ascaris, row's ascarid history.5. stool microscopy is visible
Roundworm egg, oxyphil cell can increase.6. may occur in which the complication such as biliary tract ascarid, ascaris intestinal obstruction.
Administrated method and the course for the treatment of be: a kind of Chinese medicine composition (embodiment 7) treating adenomesenteritis of the present invention,
Day 1 dose, decocting divides 2 decoction being taken warmly use, and 7 days was 1 course for the treatment of, takes 1～3 course for the treatment of.
Diagnoses and treatment standard: cure: transference cure, microscopy worm's ovum is the most negative, and blood routine examination is normal.Take a turn for the better: symptom
Improvement, microscopy worm's ovum is had not to turn out cloudy.Invalid: symptom is unchanged, microscopy worm's ovum is positive.Total effective=(recovery from illness+take a turn for the better), the most effectively
Rate=(recovery from illness+take a turn for the better)/total number of cases * 100%.
Case number of cases for ascariasis patient outcomes is as shown in table 3 below:
Case percent for ascariasis therapeutic effect is as shown in table 4 below:
| Case type | Cure (%) | Take a turn for the better (%) | Invalid (%) | Total effective (%) |
| Ascariasis | 82 | 10 | 8 | 92 |
Ascariasis model case:
1. Chen, female 8 years old.After during patient assessment, 1 day cause of private prosecution eats pungent raw food food, that night is prominent in sleep
Right upper quadrant of the abdomen pain so occurs, bores top pain in paroxysmal, and back part diffuses to the right.Simultaneously with Nausea and vomiting, tell as gastric
Tolerant and misery.Time when sending out only, toss about and feel uneasy during outbreak, dripping sweat, extreme cold of the limbs.Take Drug therapy of the present invention 1 treatment
Cheng Hou, the transference cures such as stomachache takes a turn for the better, Nausea and vomiting, fully recover after taking again 1 course for the treatment of, continue afterwards to take to consolidate 1 course for the treatment of and treat
Effect, follows up a case by regular visits to drug withdrawal over the past half year without recurrence.
2. Wang, man 12 years old.During patient assessment, 3 days causes of private prosecution and classmate have a dinner party after edible spicy hot chafing dish and cold drink, when
There is suddenly right upper quadrant of the abdomen pain in evening, bores top pain in paroxysmal, and back part diffuses to the right, time when sending out only, simultaneously with night
Grind one's teeth in sleep, Nausea and vomiting, tell as gastric content and misery.After taking 1 course for the treatment of of Drug therapy of the present invention, stomachache takes a turn for the better, feel sick,
The transference cures such as vomiting, fully recover after taking again 1 course for the treatment of, follow up a case by regular visits to drug withdrawal over 3 months without recurrence.
3. Zhang, man 14 years old.After during patient assessment, 3 days causes of private prosecution eat a large amount of barbecue and cold drink, there is suddenly the right side in that night
Epigastrium and umbilicus week pain, bore top pain in paroxysmal, and back part diffuses to the right, time when sending out the most simultaneously with Nausea and vomiting, tell
For gastric content and misery.After taking 1 course for the treatment of of Drug therapy of the present invention, the transference cures such as stomachache takes a turn for the better, Nausea and vomiting, again
Fully recover after taking 1 course for the treatment of, follow up a case by regular visits to drug withdrawal over the past half year without recurrence.
Shown by clinical trial, a kind of Chinese medicine composition treating adenomesenteritis that the present invention provides, treatment
The cure rate of ascariasis is 82%, and total effective rate is 92%, it is seen that the Chinese medicine composition that the present invention provides is to treatment ascariasis also
There is preferably curative effect.
In sum, a kind of Chinese medicine composition treating adenomesenteritis provided by the present invention, in side, Fructus Mume is held back
Lung, astringing intestine to stop diarrhea, relieving colic caused by ascaris, Rhizoma Corydalis is invigorated blood circulation, circulation of qi promoting, pain relieving, Radix Curcumae promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice, ripe attached
Son mends supporing yang, the dispelling cold and removing dampness of fire, Ramulus Cinnamomi promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins, and Cortex Phellodendri heat clearing and damp drying, pathogenic fire purging are except steaming, solving
Poison, Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication, Chinese angelica blood supplementing is invigorated blood circulation, pain relieving, loosening bowel to relieve constipation, Fructus Zanthoxyli warming spleen and stomach for dispelling cold, pain relieving, dampness, kill
Worm, Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG promote blood circulation, Herba Asari relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, Fructus Toosendan soothing liver-QI circulation of qi promoting, pain relieving, dehumidifying heat, drives
Worm, Semen Arecae parasite killing, removing food stagnancy, circulation of qi promoting, preventing the attack (or recurrence) of malaria.Scientific compatibility, the mutual synergism of each component, anti-inflammatory analgetic, antibacterial detumescence, dispels the wind
Cold expelling, heat-clearing and toxic substances removing, YANG invigorating activating QI, have splendid curative effect to treatment adenomesenteritis, for 1～the patient of 3 years old
Cure rate is up to 86%, total effective rate is up to 100%, be up to 84% for the cure rate of more than 4 years old patient, total effective rate up to
98%.And take safety.It addition, the Chinese medicine composition of the present invention can be made into multiple dosage form, equal to treatment adenomesenteritis
There is good effect, the curative effect of capsule it is further preferred that, the demand of different patient can be met.Additionally of the present invention through clinical discovery
The curative effect of traditional Chinese medicine composition for treating ascariasis the most excellent.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all essences in the present invention
Within god and principle, any modification, equivalent substitution and improvement etc. done, within should be included in the scope of protection of the invention.
Claims (6)
1. the Chinese medicine composition treating adenomesenteritis, it is characterised in that include the crude drug of following weight portion: crow
Prunus mume (sieb.) sieb.et zucc. 50～150 parts, Rhizoma Corydalis 100～200 parts, Radix Curcumae 100～200 parts, Radix Aconiti Lateralis Preparata 20～40 parts, Ramulus Cinnamomi 50～150 parts, Cortex Phellodendri 50
～150 parts, Rhizoma Coptidis 20～40 parts, Radix Angelicae Sinensis 50～150 parts, Fructus Zanthoxyli 40～60 parts, Rhizoma Zingiberis 40～60 parts, Herba Asari 15～25 parts, river
Son 100～200 parts, Semen Arecae 100～200 parts.
A kind of Chinese medicine composition treating adenomesenteritis the most according to claim 1, it is characterised in that include with
The crude drug of lower weight portion: Fructus Mume 80～120 parts, Rhizoma Corydalis 120～180 parts, Radix Curcumae 120～180 parts, Radix Aconiti Lateralis Preparata 25～35 parts,
Ramulus Cinnamomi 80～120 parts, Cortex Phellodendri 80～120 parts, Rhizoma Coptidis 25～35 parts, Radix Angelicae Sinensis 80～120 parts, Fructus Zanthoxyli 45～55 parts, Rhizoma Zingiberis 45～
55 parts, Herba Asari 18～22 parts, Fructus Toosendan 120～180 parts, Semen Arecae 120～180 parts.
A kind of Chinese medicine composition treating adenomesenteritis the most according to claim 1, it is characterised in that include with
The crude drug of lower weight portion: Fructus Mume 100 parts, Rhizoma Corydalis 150 parts, Radix Curcumae 150 parts, Radix Aconiti Lateralis Preparata 30 parts, Ramulus Cinnamomi 100 parts, Cortex Phellodendri 100
Part, Rhizoma Coptidis 30 parts, Radix Angelicae Sinensis 100 parts, Fructus Zanthoxyli 50 parts, Rhizoma Zingiberis 50 parts, Herba Asari 20 parts, Fructus Toosendan 150 parts, Semen Arecae 150 parts.
4. the Chinese medicinal composition preparation treating adenomesenteritis, it is characterised in that comprise claims 1 to 3 arbitrary
The Chinese medicine composition of the treatment adenomesenteritis described in Xiang, the Chinese medicinal composition preparation of described treatment adenomesenteritis
For granule, oral liquid, pill, the one of capsule.
5. the Chinese medicine composition of the treatment adenomesenteritis described in any one of claims 1 to 3 is at preparation treatment mesentery
Application in the medicine of lymphadenitis.
6. the Chinese medicine composition of the treatment adenomesenteritis described in any one of claims 1 to 3 is in preparation treatment ascariasis
Medicine in application.
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| CN101168038A (en) * | 2007-09-29 | 2008-04-30 | 罗华祥 | Traditional Chinese medicine for treating biliary ascariasis |
| CN102309737A (en) * | 2010-07-01 | 2012-01-11 | 李青 | Traditional Chinese medicine pill for relieving colic caused by ascaris and alleviating pain |
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