CN106266570A - A kind of Chinese medicine composition of assistant hypoglycemic and preparation method thereof - Google Patents

A kind of Chinese medicine composition of assistant hypoglycemic and preparation method thereof Download PDF

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Publication number
CN106266570A
CN106266570A CN201610833338.4A CN201610833338A CN106266570A CN 106266570 A CN106266570 A CN 106266570A CN 201610833338 A CN201610833338 A CN 201610833338A CN 106266570 A CN106266570 A CN 106266570A
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parts
clear paste
radix
chinese medicine
gained
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CN201610833338.4A
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陈亚平
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陈亚平
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The present invention relates to health protection with Chinese medicine technical field, it is specifically related to Chinese medicine composition of a kind of assistant hypoglycemic and preparation method thereof, it is to be prepared from by the raw material of following parts by weight: 10 to 15 parts of Folium Mori, Radix Puerariae 3 to 8 parts, the Radix Astragali 8 to 20 parts, 5 to 10 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 3 to 6 parts, Radix Rehmanniae 5 to 10 parts, Radix Scrophulariae 3 to 8 parts, Cortex Lycii 5 to 10 parts, have with strong points, good effect, cycle is short, price is low, the advantage such as have no side effect, patient can be made again to be willing to accept, can preferably treat diabetes, in side, each component mutually works in coordination with onset, and medicine preparation is simple, rapid-action, short treating period, diabetes are had good therapeutical effect.

Description

A kind of Chinese medicine composition of assistant hypoglycemic and preparation method thereof
Technical field
The present invention relates to health protection with Chinese medicine technical field, be specifically related to Chinese medicine composition and the preparation thereof of a kind of assistant hypoglycemic Method.
Background technology
Diabetes are a kind of endocrine and metabolic disorders diseases increasing with plasma glucose levels and being characterized, and are a kind of and something lost Biography factor and environmental factors interact, the multifactor disease jointly caused.Clinically, diabetes show typical more than 3 one Few symptom, i.e. polydipsia, polyuria, polyphagia and the symptom lost weight, its caused various complication become patient disable, lethal One of the main reasons.This disease is difficult to cure, and patient needs Long-term taking medicine, maintains blood glucose in normal range or resistance by medicine Hemostasis sugar raises further, delays increasing the weight of and the generation of complication of the state of an illness.
At present, the treatment of diabetes is many based on Western medicine, such as sulphanylureas and biguanides, although hypoglycemic effect is rapid, but makees With single, increase islets of langerhans burden, and there is the side effect such as hypoglycemia, gastrointestinal reaction, along with the prolongation for the treatment of time, blood sugar lowering Effect is in reducing trend, and long-term taking also results in Liver and kidney toxic and side effects.
Summary of the invention
For the deficiencies in the prior art, the present invention provides one to have no side effect, and is used for improving diabetics sugar, fat generation Thank and the Chinese medicine composition of a kind of assistant hypoglycemic delaying diabetes complications and preparation method thereof.
The technical scheme is that and be achieved in that: the Chinese medicine composition of a kind of assistant hypoglycemic, it is by following weight The raw material of number is prepared from: 10 to 15 parts of Folium Mori, Radix Puerariae 3 to 8 parts, the Radix Astragali 8 to 20 parts, 5 to 10 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 3 to 6 Part, Radix Rehmanniae 5 to 10 parts, Radix Scrophulariae 3 to 8 parts, Cortex Lycii 5 to 10 parts.
It is to be prepared from by the raw material of following parts by weight: 12 to 15 parts of Folium Mori, Radix Puerariae 4 to 8 parts, the Radix Astragali 10 to 18 Part, 6 to 9 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 4 to 6 parts, Radix Rehmanniae 6 to 9 parts, Radix Scrophulariae 4 to 6 parts, Cortex Lycii 6 to 9 parts.
It is to be prepared from by the raw material of following parts by weight: 14 parts of Folium Mori, Radix Puerariae 6 parts, the Radix Astragali 16 parts, 8 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 5 parts, Radix Rehmanniae 8 parts, Radix Scrophulariae 5 parts, Cortex Lycii 8 parts.
Its preparation method is as follows:
1) above-mentioned raw materials is chosen, the reflux, extract, that adds water 2 to 3 times, each amount of water is equivalent to 6 to 8 times of above-mentioned raw materials gross weight, Extraction time is 1 to 3 hour every time, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, then that filtrate is dense Being reduced to relative density when 70 to 80 degrees Celsius is the clear paste of 1.10 to 1.20;
2) being vacuum dried by gained clear paste in step 1), then pulverized by dried clear paste, the clear paste after pulverizing presses 10g Bag carries out pack and seals standby.
Its preparation method is as follows:
1) choosing above-mentioned raw materials, with 40-60% alcohol reflux 2 to 3 times, each ethanol consumption is the 4 of above-mentioned raw materials gross weight To 8 times, each extraction time is 1 to 3 hour, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, then will When filtrate is concentrated into 60 to 80 degrees Celsius, relative density is the clear paste of 1.10 to 1.20;
2) being vacuum dried by gained clear paste in step 1), then pulverized by dried clear paste, the clear paste after pulverizing presses 10g Bag carries out pack and seals standby.
The present invention has no side effect, and prescription drug pharmacology is:
Folium Mori: sweet, bitter, cold.Return lung, Liver Channel.Dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.For anemopyretic cold, lung-heat type cough, Dizziness headache, conjunctival congestion is dim-sighted.
Radix Puerariae: sweet, pungent is cool.Return spleen, stomach, lung meridian.Expelling pathogenic factors from muscles for reducing heat, promoting the production of body fluid to quench thirst, rash, yang invigorating antidiarrheal, dredge the meridian passage, Alcoholic intoxication.Have a headache for fever caused by exogenous pathogens, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, have loose bowels, dizziness and headache, middle windage yaw Paralysis, obstruction of qi in the chest and cardialgia, damage of the spleen and stomach caused by alcoholism.
The Radix Astragali: sweet, tepor.Return lung, spleen channel.Tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promote the production of body fluid and nourish blood, the stagnant blood stasis dispelling of row, Expelling pus and toxin by strengthening QI, expelling pus and promoting granulation.
Rhizoma Polygonati: sweet is flat.Return spleen, lung, kidney channel.Boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For deficiency of spleen-QI and stomach-QI, body is tired weary Power, deficiency of stomach-Yin, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, chronic cough hemoptysis, asthenia of essence and blood, soreness of the waist and knees, early whitening of beard and hair, interior-heat is quenched one's thirst.
Radix Rehmanniae: Radix Rehmanniae is sweet, bitter, cold.GUIXIN, liver, kidney channel.Radix Rehmanniae is sweet, cold.GUIXIN, liver, kidney channel.Radix Rehmanniae Clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, hematemesis and epistaxis, laryngopharynx swelling and pain.Radix Rehmanniae is clear Hot removing heat from blood, YIN nourishing and the production of body fluid promoting.
Radix Scrophulariae: sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Clearing away heat and cooling blood, nourishing YIN to lower pathogenic fire, detoxicating and resolving stagnation of pathogens.Join the army for heat Blood, maculae caused by violent heat pathogen, consumption of YIN caused by febrile disease, crimson tongue excessive thirst, constipation, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, diphtheria, scrofula, carbuncle sore tumefacting virus are hindered in Tianjin.
Cortex Lycii: sweet, cold.Return lung, liver, kidney channel.Removing heat from blood is except steaming, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, lung Heat cough, spitting of blood, epistaxis, interior-heat is quenched one's thirst.
Usage of the present invention and consumption be: the method for being prepared as described above prepares clinical sample, and specification is 10 grams every bag, within five days, is One course for the treatment of, one day three bags, take point early, middle and late three half an hour ante cibum.Take medicine period avoid eating anything raw or cold, pungent, stimulate and rot Thing.
The present invention has a following beneficial effect: have with strong points, good effect, the cycle is short, price is low, have no side effect Etc. advantage, patient can be made again to be willing to accept, can preferably treat diabetes, in side, each component mutually works in coordination with onset, and medicine system For simple, rapid-action, short treating period, diabetes are had good therapeutical effect.
Detailed description of the invention
A kind of Chinese medicine composition of assistant hypoglycemic, it is to be prepared from by the raw material of following parts by weight: Folium Mori 10 to 15 parts, Radix Puerariae 3 to 8 parts, the Radix Astragali 8 to 20 parts, 5 to 10 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 3 to 6 parts, Radix Rehmanniae 5 to 10 parts, Radix Scrophulariae 3 to 8 parts, Cortex Lycii 5 to 10 parts.It is to be prepared from by the raw material of following parts by weight: 12 to 15 parts of Folium Mori, Radix Puerariae 4 to 8 parts, the Radix Astragali 10 to 18 parts, 6 to 9 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 4 to 6 parts, Radix Rehmanniae 6 to 9 parts, Radix Scrophulariae 4 to 6 parts, Cortex Lycii 6 to 9 parts.It is by with The raw material of lower parts by weight is prepared from: 14 parts of Folium Mori, Radix Puerariae 6 parts, the Radix Astragali 16 parts, 8 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 5 parts, Radix Rehmanniae 8 Part, Radix Scrophulariae 5 parts, Cortex Lycii 8 parts.Its preparation method is as follows: 1) choose above-mentioned raw materials, and the reflux, extract, that adds water 2 to 3 times adds every time The water yield is equivalent to 6 to 8 times of above-mentioned raw materials gross weight, and each extraction time is 1 to 3 hour, merges the extracting solution of each gained, Being filtered by extracting solution, obtain filtrate, then concentrating the filtrate to relative density when 70 to 80 degrees Celsius is the clear paste of 1.10 to 1.20; 2) being vacuum dried by gained clear paste in step 1), then pulverized by dried clear paste, the clear paste after pulverizing is entered by 10g bag Luggage bag seals standby.Its preparation method is as follows: 1) choose above-mentioned raw materials, with 40-60% alcohol reflux 2 to 3 times, every time Ethanol consumption is 4 to 8 times of above-mentioned raw materials gross weight, and each extraction time is 1 to 3 hour, merges the extracting solution of each gained, Being filtered by extracting solution, obtain filtrate, then concentrating the filtrate to relative density when 60 to 80 degrees Celsius is the clear paste of 1.10 to 1.20;
2) being vacuum dried by gained clear paste in step 1), then pulverized by dried clear paste, the clear paste after pulverizing presses 10g Bag carries out pack and seals standby.
Embodiment 1: take 10 parts of Folium Mori, Radix Puerariae 3 parts, the Radix Astragali 8 parts, 5 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 3 parts, Radix Rehmanniae 5 parts, Radix Scrophulariae 3 parts, Cortex Lycii 5 parts, the reflux, extract, that they added water 2 to 3 times, each amount of water is equivalent to 6 to 8 times of above-mentioned raw materials gross weight, often Secondary extraction time is 1 to 3 hour, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, then filtrate is concentrated It is the clear paste of 1.10 to 1.20 to relative density when 70 to 80 degrees Celsius;Gained clear paste is vacuum dried, then by dried Clear paste is pulverized, and the clear paste after pulverizing carries out pack by 10g bag and seals standby.
Embodiment 2: take 15 parts of Folium Mori, Radix Puerariae 8 parts, the Radix Astragali 20 parts, 10 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 6 parts, Radix Rehmanniae 10 parts, Radix Scrophulariae 8 Part, Cortex Lycii 10 parts, the reflux, extract, that they added water 2 to 3 times, each amount of water is equivalent to the 6 to 8 of above-mentioned raw materials gross weight Times, each extraction time is 1 to 3 hour, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, then by filtrate When being concentrated into 70 to 80 degrees Celsius, relative density is the clear paste of 1.10 to 1.20;Gained clear paste is vacuum dried, then will be dried After clear paste pulverize, will pulverize after clear paste by 10g bag carry out pack seal standby.
Embodiment 3: take 12 parts of Folium Mori, Radix Puerariae 4 parts, the Radix Astragali 10 parts, 6 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 4 parts, Radix Rehmanniae 6 parts, Radix Scrophulariae 4 Part, Cortex Lycii 6 parts, reflux, extract, that they are added water 2 to 3 times, each amount of water is equivalent to 6 to 8 times of above-mentioned raw materials gross weight, Extraction time is 1 to 3 hour every time, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, then that filtrate is dense Being reduced to relative density when 70 to 80 degrees Celsius is the clear paste of 1.10 to 1.20;Gained clear paste is vacuum dried, then will be dried Clear paste pulverize, will pulverize after clear paste by 10g bag carry out pack seal standby.
Embodiment 4: take 15 parts of Folium Mori, Radix Puerariae 8 parts, the Radix Astragali 18 parts, 9 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 6 parts, Radix Rehmanniae 9 parts, Radix Scrophulariae 6 Part, Cortex Lycii 9 parts, reflux, extract, that they are added water 2 to 3 times, each amount of water is equivalent to 6 to 8 times of above-mentioned raw materials gross weight, Extraction time is 1 to 3 hour every time, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, then that filtrate is dense Being reduced to relative density when 70 to 80 degrees Celsius is the clear paste of 1.10 to 1.20;Gained clear paste is vacuum dried, then will be dried Clear paste pulverize, will pulverize after clear paste by 10g bag carry out pack seal standby.
Embodiment 5: take 14 parts of Folium Mori, Radix Puerariae 6 parts, the Radix Astragali 16 parts, 8 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 5 parts, Radix Rehmanniae 8 parts, Radix Scrophulariae 5 Part, Cortex Lycii 8 parts, reflux, extract, that they are added water 2 to 3 times, each amount of water is equivalent to 6 to 8 times of above-mentioned raw materials gross weight, Extraction time is 1 to 3 hour every time, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, then that filtrate is dense Being reduced to relative density when 70 to 80 degrees Celsius is the clear paste of 1.10 to 1.20;Gained clear paste is vacuum dried, then will be dried Clear paste pulverize, will pulverize after clear paste by 10g bag carry out pack seal standby.
Embodiment 6: take 10 parts of Folium Mori, Radix Puerariae 3 parts, the Radix Astragali 8 parts, 5 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 3 parts, Radix Rehmanniae 5 parts, Radix Scrophulariae 3 parts, They are used 40-60% alcohol reflux 2 to 3 times by Cortex Lycii 5 parts, and each ethanol consumption is the 4 to 8 of above-mentioned raw materials gross weight Times, each extraction time is 1 to 3 hour, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, then by filtrate When being concentrated into 60 to 80 degrees Celsius, relative density is the clear paste of 1.10 to 1.20;Gained clear paste is vacuum dried, then will be dried After clear paste pulverize, will pulverize after clear paste by 10g bag carry out pack seal standby.
Embodiment 7: take 15 parts of Folium Mori, Radix Puerariae 8 parts, the Radix Astragali 20 parts, 10 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 6 parts, Radix Rehmanniae 10 parts, Radix Scrophulariae 8 Part, Cortex Lycii 10 parts, they are used 40-60% alcohol reflux 2 to 3 times, each ethanol consumption is above-mentioned raw materials gross weight 4 to 8 times, each extraction time is 1 to 3 hour, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, then will When filtrate is concentrated into 60 to 80 degrees Celsius, relative density is the clear paste of 1.10 to 1.20;Gained clear paste is vacuum dried, then will Dried clear paste is pulverized, and the clear paste after pulverizing carries out pack by 10g bag and seals standby.
Embodiment 8: take 12 parts of Folium Mori, Radix Puerariae 4 parts, the Radix Astragali 10 parts, 6 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 4 parts, Radix Rehmanniae 6 parts, Radix Scrophulariae 4 Part, Cortex Lycii 6 parts, they are used 40-60% alcohol reflux 2 to 3 times, each ethanol consumption is the 4 of above-mentioned raw materials gross weight To 8 times, each extraction time is 1 to 3 hour, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, then will When filtrate is concentrated into 60 to 80 degrees Celsius, relative density is the clear paste of 1.10 to 1.20;Gained clear paste is vacuum dried, then will Dried clear paste is pulverized, and the clear paste after pulverizing carries out pack by 10g bag and seals standby.
Embodiment 9: take 15 parts of Folium Mori, Radix Puerariae 8 parts, the Radix Astragali 18 parts, 9 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 6 parts, Radix Rehmanniae 9 parts, Radix Scrophulariae 6 Part, Cortex Lycii 9 parts, they are used 40-60% alcohol reflux 2 to 3 times, each ethanol consumption is the 4 of above-mentioned raw materials gross weight To 8 times, each extraction time is 1 to 3 hour, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, then will When filtrate is concentrated into 60 to 80 degrees Celsius, relative density is the clear paste of 1.10 to 1.20;Gained clear paste is vacuum dried, then will Dried clear paste is pulverized, and the clear paste after pulverizing carries out pack by 10g bag and seals standby.
Embodiment 10: take 14 parts of Folium Mori, Radix Puerariae 6 parts, the Radix Astragali 16 parts, 8 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 5 parts, Radix Rehmanniae 8 parts, Radix Scrophulariae 5 Part, Cortex Lycii 8 parts, they are used 40-60% alcohol reflux 2 to 3 times, each ethanol consumption is the 4 of above-mentioned raw materials gross weight To 8 times, each extraction time is 1 to 3 hour, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, then will When filtrate is concentrated into 60 to 80 degrees Celsius, relative density is the clear paste of 1.10 to 1.20;Gained clear paste is vacuum dried, then will Dried clear paste is pulverized, and the clear paste after pulverizing carries out pack by 10g bag and seals standby.
Case 1: Wang, female, often feel like tired, tired, patient often feels that bipod is unable, after testing, blood glucose liter Height, for type ii diabetes in early days, after taking gliclazide 1 month, hypoglycemic effect is inconspicuous, then adds and takes clear paste of the present invention, Three times a day, each 1 bag.After 2 courses for the treatment of, blood sugar recovery is normal.
Case 2: Zhang, man, suffer from II patients with type Ⅰ DM more than 5 years, take the multi-medicaments such as metformin, effect is undesirable, Be often accompanied by intractable hand and foot numbness, trick is shaken, finger movement is ineffective and paroxysmal pain sense, violent neuritic foot pain, lower limb Paralysis, lumbago, be not desired on foot, pay attention to and two different clear, the also symptom such as autonomic nerve obstacle.Take the present invention clear Cream, three times a day, each 1 bag, after taking 1 month, above-mentioned symptom is controlled, and blood glucose is normal.
Case 3: poplar, female, often feel like fatigue, patient often feels that bipod is unable, and finger movement is ineffective and paroxysmal pain Sense, after testing, blood glucose raises, and for type ii diabetes in early days, takes metformin and gliclazide after 2 months, and hypoglycemic effect is not Substantially, clear paste of the present invention, three times a day, each 1 bag are then taken.After 3 courses for the treatment of, blood sugar recovery is normal.

Claims (5)

1. the Chinese medicine composition of an assistant hypoglycemic, it is characterised in that it is to be prepared from by the raw material of following parts by weight: 10 to 15 parts of Folium Mori, Radix Puerariae 3 to 8 parts, the Radix Astragali 8 to 20 parts, 5 to 10 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 3 to 6 parts, Radix Rehmanniae 5 to 10 parts, Radix Scrophulariae 3 to 8 parts, Cortex Lycii 5 to 10 parts.
The Chinese medicine composition of assistant hypoglycemic the most according to claim 1, it is characterised in that it is by following parts by weight Raw material is prepared from: 12 to 15 parts of Folium Mori, Radix Puerariae 4 to 8 parts, the Radix Astragali 10 to 18 parts, 6 to 9 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 4 to 6 parts, raw Radix Rehmanniae 6 to 9 parts, Radix Scrophulariae 4 to 6 parts, Cortex Lycii 6 to 9 parts.
The Chinese medicine composition of assistant hypoglycemic the most according to claim 1, it is characterised in that it is by following parts by weight Raw material is prepared from: 14 parts of Folium Mori, Radix Puerariae 6 parts, the Radix Astragali 16 parts, 8 parts of Fructus Momordicae charantiae, Rhizoma Polygonati 5 parts, Radix Rehmanniae 8 parts, Radix Scrophulariae 5 parts, ground Cortex Lycii 8 parts.
4. the preparation method of the Chinese medicine composition of an assistant hypoglycemic as claimed in claim 1, it is characterised in that its preparation side Method is as follows:
1) above-mentioned raw materials is chosen, the reflux, extract, that adds water 2 to 3 times, each amount of water is equivalent to 6 to 8 times of above-mentioned raw materials gross weight, Extraction time is 1 to 3 hour every time, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, then that filtrate is dense Being reduced to relative density when 70 to 80 degrees Celsius is the clear paste of 1.10 to 1.20;
2) being vacuum dried by gained clear paste in step 1), then pulverized by dried clear paste, the clear paste after pulverizing presses 10g Bag carries out pack and seals standby.
5. the preparation method of the Chinese medicine composition of an assistant hypoglycemic as claimed in claim 1, it is characterised in that its preparation side Method is as follows:
1) choosing above-mentioned raw materials, with 40-60% alcohol reflux 2 to 3 times, each ethanol consumption is the 4 of above-mentioned raw materials gross weight To 8 times, each extraction time is 1 to 3 hour, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, then will When filtrate is concentrated into 60 to 80 degrees Celsius, relative density is the clear paste of 1.10 to 1.20;
2) being vacuum dried by gained clear paste in step 1), then pulverized by dried clear paste, the clear paste after pulverizing presses 10g Bag carries out pack and seals standby.
CN201610833338.4A 2016-09-20 2016-09-20 A kind of Chinese medicine composition of assistant hypoglycemic and preparation method thereof CN106266570A (en)

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Publication number Priority date Publication date Assignee Title
CN108041215A (en) * 2018-01-23 2018-05-18 冯其永 A kind of coarse cereal health food and preparation method thereof

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CN102526484A (en) * 2012-02-16 2012-07-04 许从玉 Medicinal composition for decreasing blood sugar
CN103404638A (en) * 2013-07-12 2013-11-27 苏州市天灵中药饮片有限公司 Sugar-reducing tea leaves
CN105250662A (en) * 2015-08-28 2016-01-20 天津市康瑞药业有限公司 Traditional Chinese medicine dripping pills for treating mild 2 type diabetes and preparation method thereof
CN105796882A (en) * 2016-04-20 2016-07-27 袁贯丽 Auxiliary blood-sugar reducing traditional-Chinese-medicine medicament and preparing method thereof

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Publication number Priority date Publication date Assignee Title
CN102526484A (en) * 2012-02-16 2012-07-04 许从玉 Medicinal composition for decreasing blood sugar
CN103404638A (en) * 2013-07-12 2013-11-27 苏州市天灵中药饮片有限公司 Sugar-reducing tea leaves
CN105250662A (en) * 2015-08-28 2016-01-20 天津市康瑞药业有限公司 Traditional Chinese medicine dripping pills for treating mild 2 type diabetes and preparation method thereof
CN105796882A (en) * 2016-04-20 2016-07-27 袁贯丽 Auxiliary blood-sugar reducing traditional-Chinese-medicine medicament and preparing method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108041215A (en) * 2018-01-23 2018-05-18 冯其永 A kind of coarse cereal health food and preparation method thereof

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