CN106138652A - A kind of Chinese medicine composition for treating insomnia - Google Patents

A kind of Chinese medicine composition for treating insomnia Download PDF

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Publication number
CN106138652A
CN106138652A CN201610646234.2A CN201610646234A CN106138652A CN 106138652 A CN106138652 A CN 106138652A CN 201610646234 A CN201610646234 A CN 201610646234A CN 106138652 A CN106138652 A CN 106138652A
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Prior art keywords
parts
fructus
polygoni multiflori
chinese medicine
insomnia
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CN201610646234.2A
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Chinese (zh)
Inventor
李云娟
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Chengdu Jiadi Lu Sha Biotechnology Co Ltd
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Chengdu Jiadi Lu Sha Biotechnology Co Ltd
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Priority to CN201610646234.2A priority Critical patent/CN106138652A/en
Publication of CN106138652A publication Critical patent/CN106138652A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/62—Nymphaeaceae (Water-lily family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/744—Gardenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of Chinese medicine composition for treating insomnia, represent with weight portion, described endo-medicine includes Caulis Polygoni Multiflori 1 ~ 10 part, Fructus Schisandrae Chinensis 1 ~ 10 part, Bulbus Allii Fistulosi 1 ~ 10 part, Radix Polygoni Multiflori 1 ~ 10 part, Fructus Gardeniae 1 ~ 10 part, Plumula Nelumbinis 1 ~ 10 part, Herba Menthae 1 ~ 10 part, Fructus Forsythiae 1 ~ 10 part, 4 ~ 15 parts of Radix Glycyrrhizae.The present invention is based on to the understanding of insomnia mechanism and Therapeutic Principle, uses the method being directly administered orally, reinforcement and elimination in combination, has removing heat-phlegm altogether, and the effect that relieving restlessness is calmed the nerves, evident in efficacy, quality is easily controlled, and good stability has no adverse reaction substantially.

Description

A kind of Chinese medicine composition for treating insomnia
Technical field
The invention belongs to tcm field, specifically refer to a kind of Chinese medicine composition for treating insomnia.
Background technology
The quality do not had enough sleep, sleep and time that insomnia typically refers to cause because of a variety of causes can not meet ortho sleep With the psychological need of body, and produce a series of dysgenic Transient conditions by day.A lot of people have Insomnia, the one of people Life nearly all there will be insomnia.If but insomnia occurs for a long time, will damage patient, affect orthobiosis.
In China, insomnia has become the second largest disease of department of neurology outpatient service after headache, the medicine of existing treatment insomnia Thing is a lot, but curative effect is the most notable mostly, quality is wayward, poor stability, it is therefore desirable to a kind of determined curative effect and treating The medicine of effect significantly treatment insomnia.
Summary of the invention
It is an object of the invention to overcome the defect of conventional medicament, it is provided that a kind of evident in efficacy, quality is easily controlled, stability The good Chinese medicine composition for treating insomnia.
The present invention is achieved through the following technical solutions: a kind of Chinese medicine composition for treating insomnia, represents with weight portion, Described endo-medicine includes Caulis Polygoni Multiflori 1 ~ 10 part, Fructus Schisandrae Chinensis 1 ~ 10 part, Bulbus Allii Fistulosi 1 ~ 10 part, Radix Polygoni Multiflori 1 ~ 10 part, Fructus Gardeniae 1 ~ 10 part, Plumula Nelumbinis 1 ~ 10 part, Herba Menthae 1 ~ 10 part, Fructus Forsythiae 1 ~ 10 part, 4 ~ 15 parts of Radix Glycyrrhizae.
The crude drug pharmacology of a kind of Chinese medicine composition for treating insomnia of the present invention:
Caulis Polygoni Multiflori: property is put down, sweet in the mouth.GUIXIN warp, Liver Channel.Nourishing blood to tranquillize the mind, dispelling wind and removing obstruction in the collateral.Belong to the tranquilizing by nourishing the heart of sedative subordinate classification Medicine.
Fructus Schisandrae Chinensis: warm in nature, sour in the mouth, sweet.Return lung meridian, heart channel, kidney channel.Restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.Belong to and receiving Lung-intestine astringent medicinal under the classification of puckery medicine.
Bulbus Allii Fistulosi: warm in nature, acrid in the mouth.Return lung meridian, stomach warp.Deliver, activate yang, removing toxic substances, parasite killing.Belong to the pungent temperature of classification under diaphoretic medicine to solve Medicine administered to bring out the cold.
Radix Polygoni Multiflori: warm in nature is bitter in the mouth, sweet, puckery.Return Liver Channel, kidney channel, heart channel.Removing toxic substances, eliminating carbuncle, loosening bowel to relieve constipation.Belong under purgatives medicine The laxative drug of classification.
Fructus Gardeniae: cold in nature, bitter in the mouth.GUIXIN warp, lung meridian, tri-jiao channel.Pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body；Externally used detumescence Pain relieving.Belong to the heat and toxic materials clearing away medicine under antipyretic classification.
Plumula Nelumbinis: cold in nature, bitter in the mouth.Return kidney channel, heart channel.Clearing away heart-fire for tranquillization, restoring normal coordination between the heart and kidney, unsmoothing the sperm and stopping bleeding.Belong to astringent medicinal subordinate The controlling nocturnal emission with astringent drugs reducing urination leukorrhagia stopping medicine of classification.
Herba Menthae: cool in nature, acrid in the mouth.Return lung meridian, Liver Channel.Dispelling wind-heat, refresh oneself, rash.Belong to the pungent of diaphoretic medicine subordinate classification Cool diaphoretic medicine.
Fructus Forsythiae: cold nature, bitter in the mouth.Return lung meridian, heart channel, small intestine meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Belong to antipyretic subordinate to divide The heat and toxic materials clearing away medicine of class.
Radix Glycyrrhizae: property is put down, sweet in the mouth.GUIXIN warp, stomach warp, spleen channel, lung meridian.Invigorating the spleen and replenishing QI, eliminating phlegm and stopping cough, emergency analgesic therapy, mediation The property of medicine.Belong to the Qi-tonifying drug of classification under qi-restoratives medicine.
For optimizing the effect of drugs of medicine, further determine that, described Caulis Polygoni Multiflori 3 parts, Fructus Schisandrae Chinensis 3 parts, Bulbus Allii Fistulosi 3 parts, He Shou Crow 3 parts, Fructus Gardeniae 6 parts, Plumula Nelumbinis 6 parts, Herba Menthae 6 parts, Fructus Forsythiae 2 parts, 3 parts of Radix Glycyrrhizae.
For optimizing the effect of drugs of medicine, further determine that, described Caulis Polygoni Multiflori 4 parts, Fructus Schisandrae Chinensis 4 parts, Bulbus Allii Fistulosi 4 parts, He Shou Crow 8 parts, Fructus Gardeniae 8 parts, Plumula Nelumbinis 8 parts, Herba Menthae 8 parts, Fructus Forsythiae 6 parts, 10 parts of Radix Glycyrrhizae.
For optimizing the effect of drugs of medicine, further determine that, described Caulis Polygoni Multiflori 6 parts, Fructus Schisandrae Chinensis 6 parts, Bulbus Allii Fistulosi 6 parts, He Shou Crow 5 parts, Fructus Gardeniae 5 parts, Plumula Nelumbinis 5 parts, Herba Menthae 5 parts, Fructus Forsythiae 5 parts, 12 parts of Radix Glycyrrhizae.
For optimizing the effect of drugs of medicine, further determining that, described Fructus Schisandrae Chinensis is Fructus Schisandrae Chinensis (processed with vinegar).
The present invention compared with prior art, has the advantage that and has the beneficial effect that
The present invention is based on to the understanding of insomnia mechanism and Therapeutic Principle, uses directly oral method, and reinforcement and elimination in combination is common Tool removing heat-phlegm, the effect that relieving restlessness is calmed the nerves, evident in efficacy, quality is easily controlled, and good stability has no adverse reaction substantially.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, but embodiments of the present invention is not limited to this, Without departing from the idea case in the present invention described above, according to ordinary skill knowledge and customary means, make various replacing Change and change, all should be included within the scope of the invention.
Embodiment 1:
For treating the Chinese medicine composition of insomnia described in the present embodiment, representing with weight portion, described endo-medicine includes Caulis Polygoni Multiflori 1 ~ 10 parts, Fructus Schisandrae Chinensis 1 ~ 10 part, Bulbus Allii Fistulosi 1 ~ 10 part, Radix Polygoni Multiflori 1 ~ 10 part, Fructus Gardeniae 1 ~ 10 part, Plumula Nelumbinis 1 ~ 10 part, Herba Menthae 1 ~ 10 Part, Fructus Forsythiae 1 ~ 10 part, 4 ~ 15 parts of Radix Glycyrrhizae.
The preparation method of medicine of the present invention, comprises the following steps:
(1) by above-mentioned whole raw material of Chinese medicine medicines, including the crude drug taken medicine, soak 30 minutes with clear water or pure water in advance, leaching Bubble water consumption is 0.9 ~ 1.1L；
(2) raw material of Chinese medicine medicine and the liquid medicine of immersion thereof after soaking join in decocting container, add a cover and jointly decoct；
(3) first make decocting container herb liquid seethe with excitement with high heat, re-use slow fire and boil 15 ~ 20 minutes, 2 ~ 3 when boiling medicine, need to be stirred Secondary；
(4) after having decocted, add proper amount of clear water or pure water do not had medicine, carry out second time and decoct, decoct duration and degree of heating method ibid, Decocting time 15 ~ 20 minutes；
(5) leaching medicinal liquid, obtained medicinal liquid is endo-medicine.
Above-mentioned decocting container is marmite, enamel ware or rustless steel, avoids and uses ironware.
The using method of medicine of the present invention: directly take orally.
Embodiment 2:
Described in the present embodiment, important fat-reducing endo-medicine, represents with weight portion, described Caulis Polygoni Multiflori 3 parts, Fructus Schisandrae Chinensis 3 parts, Bulbus Allii Fistulosi 3 Part, Radix Polygoni Multiflori 3 parts, Fructus Gardeniae 6 parts, Plumula Nelumbinis 6 parts, Herba Menthae 6 parts, Fructus Forsythiae 2 parts, 3 parts of Radix Glycyrrhizae.
Embodiment 3:
Described in the present embodiment, important fat-reducing endo-medicine, represents with weight portion, described Caulis Polygoni Multiflori 4 parts, Fructus Schisandrae Chinensis 4 parts, Bulbus Allii Fistulosi 4 Part, Radix Polygoni Multiflori 8 parts, Fructus Gardeniae 8 parts, Plumula Nelumbinis 8 parts, Herba Menthae 8 parts, Fructus Forsythiae 6 parts, 10 parts of Radix Glycyrrhizae.
Utilize medicine of the present invention for the clinical statistics data of various obese patients:
Through the Clinical practice of 200 example patients, wherein man patient 127, female patient 73 example, medication age object 20 ~ 60 years old.Wherein Minimum 21 years old, maximum 59 years old, 38 years old mean age；Mild insomnia 42 example, moderate insomnia 72 example, moderate insomnia 36 example.
Model case:
1, field, man, 39 years old, there is insomnia because of house hold affairs before 1 month in patient, and day by day increased the weight of, difficulty falling asleep, early Can not fall asleep again after awake, awake, simultaneously with irritated, nervous, appetite decline, remember that meaning power goes down, what is all lost interest in, Being unwilling to go to work, mental status is poor, does not has happy sense, conscious decreased energy, and the morning is heavy, and afternoon is light, and before 1 week, above-mentioned symptom is more Seriously, can not fall asleep the most whole night, and with the symptom such as having palpitation, breathe hard.The prescription using the embodiment of the present invention 1 takes 3 treatments orally Journey, insomnia is wholly absent, and sleep quality is good, energetic.
2, Wang, female, there is gastric ulcer case history at an early age, usual individual character is relatively anxious, easily nervous, simple and easy waking up of often sleeping.One month Cause man has great accident, day and night ponders over and bothering, and cause to fall asleep, the phenomenon raised with blood pressure.The insomnia initial stage was once Going to a doctor to doctor trained in Western medicine psychiatric outpatient department, outpatient service physician's prescription gives tranquilizer and hypotensor, can fall asleep, but feel after rising morning after taking The most tired, portion's sense weight is not regained consciousness, and there is floating sense at the also end of walking.In using the prescription of the embodiment of the present invention 1 Taking 3 courses for the treatment of, insomnia is wholly absent, and sleep quality is good, energetic.
The above, be only presently preferred embodiments of the present invention, and the present invention not does any pro forma restriction, every depends on Any simple modification of being made above example according to the technical spirit of the present invention, equivalent variations, each fall within the protection of the present invention Within the scope of.

Claims (5)

1. the Chinese medicine composition being used for treating insomnia, it is characterised in that: representing with weight portion, described endo-medicine includes head Crow 1 ~ 10 part of rattan, Fructus Schisandrae Chinensis 1 ~ 10 part, Bulbus Allii Fistulosi 1 ~ 10 part, Radix Polygoni Multiflori 1 ~ 10 part, Fructus Gardeniae 1 ~ 10 part, Plumula Nelumbinis 1 ~ 10 part, Herba Menthae 1 ~ 10 parts, Fructus Forsythiae 1 ~ 10 part, 4 ~ 15 parts of Radix Glycyrrhizae.
A kind of Chinese medicine composition for treating insomnia the most according to claim 1, it is characterised in that: with weight portion table Show, described Caulis Polygoni Multiflori 3 parts, Fructus Schisandrae Chinensis 3 parts, Bulbus Allii Fistulosi 3 parts, Radix Polygoni Multiflori 3 parts, Fructus Gardeniae 6 parts, Plumula Nelumbinis 6 parts, Herba Menthae 6 parts, Fructus Forsythiae 2 Part, 3 parts of Radix Glycyrrhizae.
A kind of Chinese medicine composition for treating insomnia the most according to claim 1, it is characterised in that: with weight portion table Show, described Caulis Polygoni Multiflori 4 parts, Fructus Schisandrae Chinensis 4 parts, Bulbus Allii Fistulosi 4 parts, Radix Polygoni Multiflori 8 parts, Fructus Gardeniae 8 parts, Plumula Nelumbinis 8 parts, Herba Menthae 8 parts, Fructus Forsythiae 6 Part, 10 parts of Radix Glycyrrhizae.
A kind of Chinese medicine composition for treating insomnia the most according to claim 1, it is characterised in that: with weight portion table Show, described Caulis Polygoni Multiflori 6 parts, Fructus Schisandrae Chinensis 6 parts, Bulbus Allii Fistulosi 6 parts, Radix Polygoni Multiflori 5 parts, Fructus Gardeniae 5 parts, Plumula Nelumbinis 5 parts, Herba Menthae 5 parts, Fructus Forsythiae 5 Part, 12 parts of Radix Glycyrrhizae.
5. according to a kind of Chinese medicine composition for treating insomnia described in any one of claim 1 ~ 4, it is characterised in that: described Fructus Schisandrae Chinensis is Fructus Schisandrae Chinensis (processed with vinegar).
CN201610646234.2A 2016-08-09 2016-08-09 A kind of Chinese medicine composition for treating insomnia Withdrawn CN106138652A (en)

Priority Applications (1)

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CN201610646234.2A CN106138652A (en) 2016-08-09 2016-08-09 A kind of Chinese medicine composition for treating insomnia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610646234.2A CN106138652A (en) 2016-08-09 2016-08-09 A kind of Chinese medicine composition for treating insomnia

Publications (1)

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CN106138652A true CN106138652A (en) 2016-11-23

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CN201610646234.2A Withdrawn CN106138652A (en) 2016-08-09 2016-08-09 A kind of Chinese medicine composition for treating insomnia

Country Status (1)

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Application publication date: 20161123