CN106039204A - Traditional Chinese medicine composition for treating restenosis after coronary intervention and preparation method of traditional Chinese medicine composition - Google Patents

Traditional Chinese medicine composition for treating restenosis after coronary intervention and preparation method of traditional Chinese medicine composition Download PDF

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CN106039204A
CN106039204A CN201610393640.2A CN201610393640A CN106039204A CN 106039204 A CN106039204 A CN 106039204A CN 201610393640 A CN201610393640 A CN 201610393640A CN 106039204 A CN106039204 A CN 106039204A
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王嘉兴
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王嘉兴
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61K36/11Pteridophyta or Filicophyta (ferns)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/236Ligusticum (licorice-root)
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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    • A61K36/88Liliopsida (monocotyledons)
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract

This invention discloses traditional Chinese medicine composition for treating restenosis after coronary intervention. The traditional Chinese medicine composition is prepared from the following raw materials: 4-10 g of raw milkvetch root, 3-9 g of salvia miltiorrhiza, 4-12 g of ophiopogon japonicus, 5-15 g of Chinese magnoliavine fruit, 4-12 g of red peony root, 2-6 g of peach seed, 3-7 g of rhizoma Chuanxiong, 4-12 g of bitter orange, 5-15 g of rhizoma corydalis, 3-9 g of radix curcumae, 4-12 g of poria cocos, 4-12 g of stir-fried spina date seed, 5-15 g of lily bulb, 4-10 g of officinal cinnamon, 3-9 g of short-horned epimedium herb, 2-4 g of rhizome of Scythian Lamb, 2-4 g of morinda root, 3-9 g of raw eucommia bark, 4-12 g of Chinese taxillus herb, 5-9 g of manchurian wildginger, 3-9 g of common aucklandia root and 4-12 g of Chicken's gizzard-membrane. The invention also discloses a preparation method of the traditional Chinese medicine composition for treating the restenosis after coronary intervention. The traditional Chinese medicine composition has reasonable compatibility, significant conditioning effect and good lasting effect and can effectively inhibit the restenosis after coronary intervention, while has no toxic or side effects.

Description

A kind of Chinese medicine composition treating restenosis after coronary intervention and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine and preparation method thereof, particularly relate to a kind for the treatment of in restenosis after coronary intervention Drug composition and preparation method thereof.
Background technology
Percutaneous coronary artery intervention, becomes coronary heart disease Revascularization because it can open rapidly inaccessible blood vessel Important means, but after coronary artery bracket is inserted, still suffer from occurring the probability of restenosis, affect the late result of interventional therapy, Therefore, how prevention of restenosis has become as one of Chinese medicine problem that current cardiac disease research field faced.At present, use Drug therapy has become as the important means of clinical treatment restenosis, and the inhibition of Western medicine short-term to a certain extent is relatively strong, But need Long-term taking medicine, easily cause the drug dependence of patient and other bodily tissues are caused the biggest toxic and side effects; Chinese medicine is for current, and the effect of alleviation is preferable, but lasting curative effect is inadequate, and reason mainly cannot find a kind of compatibility reasonable Chinese medicine formula.
Summary of the invention
The present invention is aiming at the problems referred to above, propose a kind of Chinese medicine composition treating restenosis after coronary intervention and Preparation method, this Chinese medicine composition is to preventing restenosis after coronary intervention to have obvious inhibiting effect, and lasting effect is good, nothing Toxic and side effects.
For reaching above-mentioned technical purpose, present invention employs a kind of Chinese medicine composition treating restenosis after coronary intervention Thing, is made up of the raw material of following component: Radix Astragali 4-10 gram, Radix Salviae Miltiorrhizae 3-9 gram, Radix Ophiopogonis 4-12 gram, Fructus Schisandrae Chinensis 5-15 gram, Radix Paeoniae Rubra 4- 12 grams, 2-6 gram of Semen Persicae, Rhizoma Chuanxiong 3-7 gram, Fructus Aurantii 4-12 gram, Rhizoma Corydalis 5-15 gram, Radix Curcumae 3-9 gram, 4-12 gram of Poria, Semen Ziziphi Spinosae (parched) 4-12 gram, Bulbus Lilii 5-15 gram, medicinal Cortex Cinnamomi 4-10 gram, Herba Epimedii 3-9 gram, Rhizoma Cibotii 2-4 gram, Radix Morindae Officinalis 2-4 gram, Cortex Eucommiae 3-9 Gram, Herba Taxilli 4-12 gram, Herba Asari 5-9 gram, Radix Aucklandiae 3-9 gram, Endothelium Corneum Gigeriae Galli 4-12 gram.
The invention also discloses the preparation method of a kind of Chinese medicine composition treating restenosis after coronary intervention, by above-mentioned Medicine cleans, sterilize, dry after, be sufficiently mixed, be then placed in pulverizer and be crushed to 150-200 mesh, place into 100-120 DEG C of baking After drying in dry machine, medicated powder is loaded capsule.
Owing to putting into and interventional therapy is exogenous wound, consequential damage channels, can gas consumption blood trouble, make that internal organs are deficient to be added Weight, and the hyperamization stasis of blood, expectorant is turbid waits pathological product again to be formed, simultaneously can with spontaneous perspiration, breathe hard, cardiopalmus, xerostomia etc., the medicine of the present invention In thing, Radix Astragali, Radix Salviae Miltiorrhizae, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Radix Paeoniae Rubra, Semen Persicae, Rhizoma Chuanxiong, Fructus Aurantii, Rhizoma Corydalis, Radix Curcumae, Poria, Bulbus Lilii etc. have Effect that boosting qi and nourishing yin, blood circulation promoting and blood stasis dispelling are promoted blood circulation;The most on this basis, addition temperature compensation heart kidney, benefiting qi and supporting yang, dredging collateral is needed to nourish heart Medicine, medicinal Cortex Cinnamomi that the present invention collects, Herba Epimedii, Rhizoma Cibotii, Radix Morindae Officinalis, Cortex Eucommiae, Herba Asari have above-mentioned effect.
Generally speaking, the pharmaceutical composition compatibility of the present invention is reasonable, and conditioning effect is notable, can effectively suppress coronary heart disease to get involved Rear restenosis, and lasting effect is good, has no side effect.
Detailed description of the invention
Use detailed description of the invention that the present invention is described in more detail below.
Embodiment 1
A kind of Chinese medicine composition treating restenosis after coronary intervention, is made up of the raw material of following component: Radix Astragali 4 grams, pellet Join 3 grams, Radix Ophiopogonis 4 grams, Fructus Schisandrae Chinensis 5 grams, Radix Paeoniae Rubra 4 grams, 2 grams of Semen Persicae, Rhizoma Chuanxiong 3 grams, Fructus Aurantii 4 grams, Rhizoma Corydalis 5 grams, Radix Curcumae 3 grams, Fu Siberian cocklebur 4 grams, Semen Ziziphi Spinosae (parched) 4 grams, Bulbus Lilii 5 grams, medicinal Cortex Cinnamomi 4 grams, Herba Epimedii 3 grams, Rhizoma Cibotii 2 grams, Radix Morindae Officinalis 2 grams, Cortex Eucommiae 3 grams, Mulberry Parasitism 4 grams, Herba Asari 5 grams, the Radix Aucklandiae 3 grams, Endothelium Corneum Gigeriae Galli 4 grams.
The preparation method of the pharmaceutical composition of the present invention is: after said medicine being cleaned, sterilizing, dry, be sufficiently mixed, so After put into pulverizer and be crushed to 150-200 mesh, after drying in placing into 100-120 DEG C of dehydrator, medicated powder is loaded capsule.
The another kind of preparation method of the pharmaceutical composition of the present invention is as follows: after said medicine being cleaned, sterilizing, dry, put Enter the fried medicine juice of decoction vessel, cool down under taking liquid room temperature after filter inner filtration three times, cold preservation under the conditions of being packaged in 2-4 DEG C.
The using method of the pharmaceutical composition of the present invention is: oral, capsule is each three, three times on the one;Medicinal liquid is every Secondary 5 milliliters, four times a day.
Embodiment 2
A kind of Chinese medicine composition treating restenosis after coronary intervention, is made up of the raw material of following component: Radix Astragali 10 grams, pellet Join 9 grams, Radix Ophiopogonis 12 grams, Fructus Schisandrae Chinensis 15 grams, Radix Paeoniae Rubra-12 grams, 6 grams of Semen Persicae, Rhizoma Chuanxiong 7 grams, Fructus Aurantii 12 grams, Rhizoma Corydalis 15 grams, Radix Curcumae 9 Gram, 12 grams of Poria, Semen Ziziphi Spinosae (parched) 12 grams, Bulbus Lilii 15 grams, medicinal Cortex Cinnamomi 10 grams, Herba Epimedii 9 grams, Rhizoma Cibotii 4 grams, Radix Morindae Officinalis 4 grams, raw Du Secondary 9 grams, Herba Taxilli 12 grams, Herba Asari 9 grams, the Radix Aucklandiae 9 grams, Endothelium Corneum Gigeriae Galli 12 grams.
The preparation method of the medicine of the present embodiment and using method are with embodiment 1.
Embodiment 3
A kind of Chinese medicine composition treating restenosis after coronary intervention, is made up of the raw material of following component: Radix Astragali 7 grams, pellet Join 6 grams, Radix Ophiopogonis 8 grams, Fructus Schisandrae Chinensis 10 grams, Radix Paeoniae Rubra 8 grams, 4 grams of Semen Persicae, Rhizoma Chuanxiong 5 grams, Fructus Aurantii 8 grams, Rhizoma Corydalis 10 grams, Radix Curcumae 6 grams, 8 grams of Poria, Semen Ziziphi Spinosae (parched) 8 grams, Bulbus Lilii 10 grams, medicinal Cortex Cinnamomi 7 grams, Herba Epimedii 6 grams, Rhizoma Cibotii 3 grams, Radix Morindae Officinalis 3 grams, Cortex Eucommiae 6 grams, Herba Taxilli 8 grams, Herba Asari 7 grams, the Radix Aucklandiae 6 grams, Endothelium Corneum Gigeriae Galli 8 grams.
The preparation method of the medicine of the present embodiment and using method are with embodiment 1.

Claims (3)

1. the Chinese medicine composition treating restenosis after coronary intervention, it is characterised in that be made up of the raw material of following component: Radix Astragali 4-10 gram, Radix Salviae Miltiorrhizae 3-9 gram, Radix Ophiopogonis 4-12 gram, Fructus Schisandrae Chinensis 5-15 gram, Radix Paeoniae Rubra 4-12 gram, 2-6 gram of Semen Persicae, Rhizoma Chuanxiong 3-7 Gram, Fructus Aurantii 4-12 gram, Rhizoma Corydalis 5-15 gram, Radix Curcumae 3-9 gram, 4-12 gram of Poria, Semen Ziziphi Spinosae (parched) 4-12 gram, Bulbus Lilii 5-15 gram, medicinal Cortex Cinnamomi 4-10 gram, Herba Epimedii 3-9 gram, Rhizoma Cibotii 2-4 gram, Radix Morindae Officinalis 2-4 gram, Cortex Eucommiae 3-9 gram, Herba Taxilli 4-12 gram, Herba Asari 5-9 Gram, Radix Aucklandiae 3-9 gram, Endothelium Corneum Gigeriae Galli 4-12 gram.
The preparation method of a kind of Chinese medicine composition treating restenosis after coronary intervention, it is special Levy and be, after said medicine is cleaned, sterilizing, dry, be sufficiently mixed, be then placed in pulverizer and be crushed to 150-200 mesh, then put After drying in entering 100-120 DEG C of dehydrator, medicated powder is loaded capsule.
The preparation method of a kind of Chinese medicine composition treating restenosis after coronary intervention, it is special Levy and be, after said medicine being cleaned, sterilizing, dry, put into the fried medicine juice of decoction vessel, taking liquid after filter inner filtration three times Cool down under room temperature, cold preservation under the conditions of being packaged in 2-4 DEG C.
CN201610393640.2A 2016-06-06 2016-06-06 Traditional Chinese medicine composition for treating restenosis after coronary intervention and preparation method of traditional Chinese medicine composition Withdrawn CN106039204A (en)

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Application publication date: 20161026