CN106038010A - Cardiovascular artery stent - Google Patents

Cardiovascular artery stent Download PDF

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Publication number
CN106038010A
CN106038010A CN 201610335723 CN201610335723A CN106038010A CN 106038010 A CN106038010 A CN 106038010A CN 201610335723 CN201610335723 CN 201610335723 CN 201610335723 A CN201610335723 A CN 201610335723A CN 106038010 A CN106038010 A CN 106038010A
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parts
mass
balance
connecting
annular body
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CN 201610335723
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Chinese (zh)
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CN106038010B (en )
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孙三友
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孙三友
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02Inorganic materials
    • A61L31/022Metals or alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/082Inorganic materials
    • A61L31/088Other specific inorganic materials not covered by A61L31/084 or A61L31/086
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2420/00Materials or methods for coatings medical devices
    • A61L2420/06Coatings containing a mixture of two or more compounds

Abstract

The invention discloses a cardiovascular artery stent, which comprises a plurality of annular bodies and a plurality of connecting parts which are connected to the annular bodies, wherein the connecting parts and the annular bodies are coated with coatings; each annular body is provided with a plurality of triangular rib beams which are uniformly distributed along rings; the connecting parts are provided with V-shaped connecting rods; and spiral buckles, which are connected to the annular bodies, are arranged at the ends of the connecting rods. With the design of the V-shaped connecting rods, the cardiovascular artery stent has a certain flexibility, and by virtue of the buckles at the ends, the cardiovascular artery stent is more convenient to separate; by virtue of the triangular rib beams, the weight of the stent is relieved, and meanwhile, the intensity of the annular bodies is guaranteed; and with the application of the coating materials, the compatibility and corrosion resistance of the stent are improved, and meanwhile, the growth of scar tissues is inhibited.

Description

一种心血管动脉支架[0001] One cardiovascular Stent [0001]

技术领域 FIELD

[0002] 本发明涉一种心血管动脉支架,属于心血管技术领域。 [0002] The present invention relates to one cardiovascular arterial stents, cardiovascular technical field belongs. 背景技术 Background technique

[0003] 目前,冠状动脉疾病是心血管疾病中最常见的疾病,也是死亡率和发病率较高的疾病,其主要原因是动脉粥样硬化导致的血管狭窄。 [0003] Currently, coronary artery disease is the most common cardiovascular disease is high morbidity and mortality, mainly due to atherosclerosis of vascular stenosis caused. 治疗冠状动脉疾病最常用的方法是利用球囊打开血管狭窄,然后永久性放置金属支撑材料,即众所周知的支架。 Treatment of coronary artery disease is the most common way to open the stenosis with a balloon, and then placing a permanent metal support material, known as a stent. 然而支架置入术后内膜的过度增生会导致再狭窄的发生,单纯裸支架再狭窄的发生率可达10-30 %,故冠状动脉支架置入术后再狭窄一直是冠心病介入治疗研究中的重中之重,其中以冠脉内支架涂层的研究尤为突出。 However, after the stent placement intimal hyperplasia can lead to restenosis, restenosis rates of up to 10-30% pure bare-metal stents, coronary stent after it has been the treatment of restenosis of coronary intervention top priority, to study the coronary stent wherein the coating is particularly prominent. 发明内容 SUMMARY

[0004] —种心血管动脉支架,包括多个环状体和所述多个用于连接所述环状体的连接部件,连接部件和环状体包覆有涂层,环状体具有多个沿环均匀分布的三角形筋梁,连接部件具有V形连接杆,连接杆端部具有用于连接环状体的螺旋扣,连接部件为铜基合金材料,其元素组成为(质量百分比):〇12-13%,3114-5%,2112-3%, Mo 0.5-0.6%, Mg 0.3-0.4%,Fe 0.1-0.2%,N1.08-0.09%, B 0.08-0.09%,Nd 0.05-0 • 06%,Ga 0 • 04-0 • 05%,CaO • 02-0 • 03%,余量为Cu,环状体为钛基合金材料,其元素组成为(质量百分比):Cr 7-8%,Si 4-5%,Zn 5-6%,B 1-2%,V 0.8-0.9%, Zr 0.7-0.8%, Bi 0.2-0.3%, Ag 0.2-0.3%,Mg0.1-0.2%, La 0.08-0.09%,Y 0.04-0.05%,Nb0.06-0.07%,余量为Ti,涂层包括以下质量份数组分:碳化硼20-30份,氧化镍10-20份,六硼化钙7-8份,氧化铝1 -2份,碳化铌0.7-0.8份,二硅化钼0.5-0.6份。 [0004] - cardiovascular species arterial stent comprising a plurality of said annular body and a plurality of connecting members for connecting the annular member, the connecting member and the annular member is coated with a coating having a plurality of annular body uniformly distributed along the ring a triangular reinforcement beam, the connecting member having a V-shaped connecting rod, the connecting rod having an end portion of copper-based alloy material for the turnbuckle, the connecting member connecting annular body which elemental composition (mass percentage): 〇12-13%, 3114-5%, 2112-3%, Mo 0.5-0.6%, Mg 0.3-0.4%, Fe 0.1-0.2%, N1.08-0.09%, B 0.08-0.09%, Nd 0.05- 0 • 06%, Ga 0 • 04-0 • 05%, CaO • 02-0 • 03%, the balance is Cu, the annular body is a titanium-based alloy material having elemental composition (percent by mass): Cr 7- 8%, Si 4-5%, Zn 5-6%, B 1-2%, V 0.8-0.9%, Zr 0.7-0.8%, Bi 0.2-0.3%, Ag 0.2-0.3%, Mg0.1-0.2 %, La 0.08-0.09%, Y 0.04-0.05%, Nb0.06-0.07%, the balance being Ti, a coating mass comprising the components parts: 20-30 parts of boron carbide, nickel oxide, 10-20 parts, six 7-8 parts of calcium boride, alumina, 1-2 parts 0.7-0.8 parts of niobium carbide, molybdenum disilicide 0.5-0.6 parts. 所述的一种心血管动脉支架,连接部件为铜基合金材料,其元素组成为(质量百分比): Cr 12%,Sn 4%, Zn 2%, Mo 0.5%, Mg 0.3%,Fe 0.l%,N1.08%, B 0.08%,Nd 0.05%,Ga 0 • 04%,CaO • 02%,余量为Cu。 Said one cardiovascular arterial stent member is connected to copper-based alloy material having elemental composition (percent by mass): Cr 12%, Sn 4%, Zn 2%, Mo 0.5%, Mg 0.3%, Fe 0. l%, N1.08%, B 0.08%, Nd 0.05%, Ga 0 • 04%, CaO • 02%, the balance being Cu.

[0005] 所述的一种心血管动脉支架,连接部件为铜基合金材料,其元素组成为(质量百分比):Cr 12.5%,Sn 4.5%, Zn 2.5%, Mo 0.55%, Mg 0.35%,Fe 0.15%,Ni0.085%, B 0.085%,Nd 0.055%,Ga 0.045%,Ca0.025%,余量为Cu。 One cardiovascular Stent [0005], wherein the connecting member is a copper-based alloy material having elemental composition (percent by mass): Cr 12.5%, Sn 4.5%, Zn 2.5%, Mo 0.55%, Mg 0.35%, Fe 0.15%, Ni0.085%, B 0.085%, Nd 0.055%, Ga 0.045%, Ca0.025%, the balance being Cu.

[0006] 所述的一种心血管动脉支架,连接部件为铜基合金材料,其元素组成为(质量百分比):Cr 13%,Sn 5%, Zn 3%, Mo 0.6%, Mg 0.4%,Fe 0.2%,Ni 0.09%, B 0.09%,Nd 0.06%, Ga 0.05%,Ca 0.03%,余量为Cu。 One cardiovascular Stent [0006], wherein the connecting member is a copper-based alloy material having elemental composition (percent by mass): Cr 13%, Sn 5%, Zn 3%, Mo 0.6%, Mg 0.4%, Fe 0.2%, Ni 0.09%, B 0.09%, Nd 0.06%, Ga 0.05%, Ca 0.03%, the balance being Cu.

[0007] 所述的一种心血管动脉支架,环状体为钛基合金材料,其元素组成为(质量百分比):Cr 7%,Si 4%,Zn 5%, B 1%,V 0.8%, Zr 0.7%, Bi 0.2%, Ag 0.2%,Mg0.1%, La0.08%,Y 0.04%,Nb0.06%,余量为Ti。 One cardiovascular Stent [0007], wherein the annular body is a titanium-based alloy material having elemental composition (percent by mass): Cr 7%, Si 4%, Zn 5%, B 1%, V 0.8% , Zr 0.7%, Bi 0.2%, Ag 0.2%, Mg0.1%, La0.08%, Y 0.04%, Nb0.06%, the balance is Ti.

[0008] 所述的一种心血管动脉支架,环状体为钛基合金材料,其元素组成为(质量百分比):Cr 8%,Si 5%,Zn 6%, B 2%,V 0.9%, Zr 0.8%, Bi 0.3%, Ag 0.3%,Mg 0.2%, La 0.09%,Y 0.05%,Nb 0.07%,余量为Ti。 One cardiovascular Stent [0008], wherein the annular body is a titanium-based alloy material having elemental composition (percent by mass): Cr 8%, Si 5%, Zn 6%, B 2%, V 0.9% , Zr 0.8%, Bi 0.3%, Ag 0.3%, Mg 0.2%, La 0.09%, Y 0.05%, Nb 0.07%, the balance is Ti.

[0009] 所述的一种心血管动脉支架,环状体为钛基合金材料,其元素组成为(质量百分bt):Cr 7.5%,Si 4.5%,Zn 5.5%, B 1.5%,V 0.85%, Zr 0.75%, Bi 0.25%, Ag 0.25%, Mg0.15%,La 0.085%,Y 0.045%,Nb0.065%,余量为Ti。 One cardiovascular arterial stents, the annular body [0009] according to a titanium-based alloy material consisting of elements (mass percent bt): Cr 7.5%, Si 4.5%, Zn 5.5%, B 1.5%, V 0.85%, Zr 0.75%, Bi 0.25%, Ag 0.25%, Mg0.15%, La 0.085%, Y 0.045%, Nb0.065%, the balance is Ti.

[0010] 所述的一种心血管动脉支架,涂层包括:碳化硼20份,氧化镍10份,六硼化钙7份, 氧化铝1份,碳化铌0.7份,二硅化钼0.5份。 One cardiovascular Stent [0010], wherein the coating comprises: 20 parts of boron carbide, 10 parts of nickel oxide, 7 parts of calcium hexaboride, 1 part of alumina, 0.7 parts of niobium carbide, molybdenum disilicide 0.5 parts.

[0011] 所述的一种心血管动脉支架,涂层包括:碳化硼30份,氧化镍20份,六硼化钙8份, 氧化铝2份,碳化铌0.8份,二硅化钼0.6份。 One cardiovascular Stent [0011], wherein the coating comprises: 30 parts of boron carbide, nickel oxide, 20 parts of calcium hexaboride 8 parts, 2 parts alumina, 0.8 parts of niobium carbide, molybdenum disilicide 0.6 parts. [〇〇12]所述的一种心血管动脉支架,涂层包括:碳化硼25份,氧化镍15份,六硼化钙7.5 份,氧化铝1.5份,碳化铌0.75份,二硅化钼0.55份。 One cardiovascular artery stenting [〇〇12], wherein the coating comprises: 25 parts of boron oxide, 15 parts of nickel, 7.5 parts of calcium hexaboride, 1.5 parts alumina, 0.75 parts of niobium carbide, molybdenum disilicide 0.55 copies.

[0013] 述发明内容相对于现有技术的有益效果在于:1)环状体使用钛合金保证了其强度需要,连接部件使用铜基合金其具有一定弹性和韧性保证形状的稳定性;2)本发明心血管动脉支架采用连接部件和环状体分体结构保证了支架的支撑性又保证了其与血管的顺,并且还可以根据需要方便的调整长度;3)V形连接杆设计保证了心血管动脉支架具有一定的柔性,端部的扣子使得分离更加方便;4)三角形筋梁可以既减轻了支架的质量又保证了环状体的强度,5)涂层材料提高支架的相容性耐腐蚀性并且抑制疤痕组织生长。 [0013] Summary of the invention described with respect to the prior art is that the beneficial effects: 1) the use of an annular member to ensure its required strength titanium alloy, copper-based alloy using the connecting member which has a certain elasticity and toughness to ensure the shape stability; 2) cardiovascular arterial stents of the present invention uses the connecting member and a separate annular body supporting structure ensures the stent and ensure its cis and blood vessels, and can also easily adjust the length; 3) V-shaped design ensures that the connecting rod arterial cardiovascular stent having a certain flexibility, the end portion of the buttons so that the separation is more convenient; 4) triangular reinforcement beam can only reduce the quality of the stent and ensure the strength of the annular body, 5) a coating material to improve the compatibility of the stent corrosion resistance and to suppress the growth of scar tissue.

[0014]附图说明 [0014] BRIEF DESCRIPTION OF DRAWINGS

[0015] 图1为心血管动脉支架示意图;图2为连接部件示意图;图3为环状体不意图。 [0015] FIG. 1 is a schematic view of the arterial cardiovascular stents; FIG. 2 is a schematic view of the connection member; FIG. 3 is an annular body is not intended. 具体实施方式 Detailed ways

[0016] 为了对本发明的技术特征、目的和效果有更加清楚的理解,现详细说明本发明的具体实施方式。 [0016] For the technical characteristics of the invention, the objects and effects more clearly understood, embodiments of the present invention will now be described in detail.

[0017] 如图1-3所示一种心血管动脉支架,包括多个环状体1和所述多个用于连接所述环状体的连接部件2,环状体具有多个沿环均匀分布的三角形筋梁3,连接部件具有V形连接杆4,连接杆端部具有用于连接环状体的螺旋扣5,连接部件和环状体使用精密铸造方法制造,环状体上还包括使环状体和连接杆端部扣件相连的配合部件(附图未示出),实施例1一种心血管动脉支架,包括多个环状体和所述多个用于连接所述环状体的连接部件, 连接部件和环状体包覆有涂层,环状体具有多个沿环均匀分布的三角形筋梁,连接部件具有V形连接杆,连接杆端部具有用于连接环状体的螺旋扣,连接部件为铜基合金材料,其元素组成为(质量百分比):Cr 12%,Sn 4%,Zn 2%,Mo0.6%,Mg 0.4%,Fe 0.1%,Ni0.09%,B 0.08%,Nd 0.06%,Ga 0.04%,Ca0.03%,余量为Cu,环状体为钛基合金材料,其元素组成为( [0017] As shown in FIG. 1-3 one cardiovascular arterial stents, comprising a plurality of annular body 1 and the plurality of connecting members for connecting the annular body 2, having a plurality of annular rings along beams evenly distributed triangles 3, the connecting member having a V-shaped connecting rods 4, further having a connecting rod for connecting the end portion of the turnbuckle annular body 5, the connecting member and the annular member using the method of manufacturing a precision casting, annular body the mating member includes an annular body portion and the connecting rod end is connected to a fastener (not shown in the drawings), Example 1 one cardiovascular stenting embodiment, comprises a plurality of said annular body and a plurality of connection for the an annular body connecting member, the connecting member and the annular member is coated with a coating, an annular beam having a plurality of triangular ribs uniformly distributed along the ring, the connecting member having a V-shaped connecting rod, the connecting rod having a connecting end portion turnbuckle annular body, the connecting member is a copper-based alloy material having elemental composition (percent by mass): Cr 12%, Sn 4%, Zn 2%, Mo0.6%, Mg 0.4%, Fe 0.1%, Ni0 .09%, B 0.08%, Nd 0.06%, Ga 0.04%, Ca0.03%, the balance is Cu, the annular body is a titanium-based alloy material consisting of elements ( 量百分比):Cr 7%,Si 4%,Zn 6%,B 2%,V 0.8%,Zr 0.7%,Bi 0.2%,Ag 0.3%,Mg0.2%,La 0.08%,Y 0.05%,Nb0.06%,余量为Ti, 涂层包括:碳化硼20份,氧化镍10份,六硼化钙8份,氧化铝2份,碳化铌0.7份,二硅化钼0.5份。 Percentage amount): Cr 7%, Si 4%, Zn 6%, B 2%, V 0.8%, Zr 0.7%, Bi 0.2%, Ag 0.3%, Mg0.2%, La 0.08%, Y 0.05%, Nb0 .06%, the balance being Ti, a coating comprising: 20 parts of boron carbide, 10 parts of nickel oxide, 8 parts of calcium hexaboride, 2 parts alumina, 0.7 parts of niobium carbide, molybdenum disilicide 0.5 parts. [〇〇18] 实施例2一种心血管动脉支架,包括多个环状体和所述多个用于连接所述环状体的连接部件, 连接部件和环状体包覆有涂层,环状体具有多个沿环均匀分布的三角形筋梁,连接部件具有V形连接杆,连接杆端部具有用于连接环状体的螺旋扣,连接部件为铜基合金材料,其元素组成为(质量百分比):Cr 13%,Sn 5%,Zn 3%,Mo 0.5%,Mg 0.4%,Fe 0.1%,Ni0.09%,B 0.09%,Nd 0.06%,Ga 0.05%,Ca0.02%,余量为Cu,环状体为钛基合金材料,其元素组成为(质量百分比):Cr 8%,Si 5%,Zn 6%,B 2%,V 0.9%,Zr 0.8%,Bi 0.2%,Ag 0.3%,Mg0.2%,La 0.09%,Y 0.05%,Nb0.06%,余量为Ti, 涂层包括:碳化硼20份,氧化镍20份,六硼化钙7份,氧化铝2份,碳化铌0.8份,二硅化钼0.6份。 [〇〇18] Example 2 one cardiovascular arterial stent comprising a plurality of said annular body and a plurality of connecting members for connecting the annular member, the connecting member and the annular member is coated with a coating, an annular beam having a plurality of triangular ribs uniformly distributed along the ring, the connecting member having a V-shaped connecting rod, the connecting rod end has a copper-based alloy material for the annular body connected to the turnbuckle, the connecting member is that elemental composition (percent by mass): Cr 13%, Sn 5%, Zn 3%, Mo 0.5%, Mg 0.4%, Fe 0.1%, Ni0.09%, B 0.09%, Nd 0.06%, Ga 0.05%, Ca0.02% , the balance being Cu, the annular body is a titanium-based alloy material having elemental composition (percent by mass): Cr 8%, Si 5%, Zn 6%, B 2%, V 0.9%, Zr 0.8%, Bi 0.2 %, Ag 0.3%, Mg0.2%, La 0.09%, Y 0.05%, Nb0.06%, the balance being Ti, a coating comprising: 20 parts of boron carbide, nickel oxide 20 parts, 7 parts of calcium hexaboride, 2 parts of aluminum oxide, niobium carbide, 0.8 parts, 0.6 parts of molybdenum disilicide.

[0019] 实施例3一种心血管动脉支架,包括多个环状体和所述多个用于连接所述环状体的连接部件, 连接部件和环状体包覆有涂层,环状体具有多个沿环均匀分布的三角形筋梁,连接部件具有V形连接杆,连接杆端部具有用于连接环状体的螺旋扣,连接部件为铜基合金材料,其元素组成为(质量百分比):Cr 12.5%,Sn 4.5%,Zn 2.5%, Mo 0.55%, Mg 0.35%,Fe 0.15%,Ni0.085%, B 0.085%,Nd 0.055%,Ga 0.045%, 〇&0.025%,余量为〇1,环状体为钛基合金材料,其元素组成为(质量百分比):Cr 7.5%,Si 4.5%,Zn 5.5%,B 1.5%,V 0.85%, Zr 0.75%, Bi 0.25%, Ag 0.25%,Mg0.15%, La 0.085%, Y 0.045%, Nb0.065%,余量为Ti,涂层包括:碳化硼25份,氧化镍15份,六硼化钙7.5份,氧化铝1.5份,碳化铌0.75份,二硅化钼0.55份。 [0019] Example 3 one cardiovascular arterial stent comprising a plurality of said annular body and a plurality of connecting members for connecting the annular member, the connecting member and the annular member is coated with a coating, cyclic a plurality of beams having triangular ribs uniformly distributed along the ring, the connecting member having a V-shaped connecting rod, the connecting rod having an end portion of copper-based alloy material for the turnbuckle, the connecting member connecting annular body which elemental composition (mass percentage): Cr 12.5%, Sn 4.5%, Zn 2.5%, Mo 0.55%, Mg 0.35%, Fe 0.15%, Ni0.085%, B 0.085%, Nd 0.055%, Ga 0.045%, 0.025% & square, 〇1 balance, the annular body is a titanium-based alloy material having elemental composition (percent by mass): Cr 7.5%, Si 4.5%, Zn 5.5%, B 1.5%, V 0.85%, Zr 0.75%, Bi 0.25 %, Ag 0.25%, Mg0.15%, La 0.085%, Y 0.045%, Nb0.065%, the balance being Ti, a coating comprising: 25 parts of boron oxide, 15 parts of nickel, 7.5 parts of calcium hexaboride, 1.5 parts alumina, 0.75 parts of niobium carbide, 0.55 parts of molybdenum disilicide.

[0020] 实施例4一种心血管动脉支架,包括多个环状体和所述多个用于连接所述环状体的连接部件, 连接部件和环状体包覆有涂层,环状体具有多个沿环均匀分布的三角形筋梁,连接部件具有V形连接杆,连接杆端部具有用于连接环状体的螺旋扣,连接部件为铜基合金材料,其元素组成为(质量百分比):Cr 12.4%,Sn 4.3%,Zn 2.2%, Mo 0.57%, Mg 0.36%,Fe 0.18%,Ni0.089%, B 0.088%,Nd 0.057%,Ga 0.046%, 〇&0.029%,余量为〇1,环状体为钛基合金材料,其元素组成为(质量百分比):Cr 7.7%,Si 4.4%,Zn 5.3%,B 1.4%,V 0.88%, Zr 0.77%, Bi 0.24%, Ag 0.23%,Mg0.12%, La 0.082%, Y 0.041%, Nb0.063%,余量为Ti,涂层包括:碳化硼28份,氧化镍14份,六硼化钙7.8份,氧化铝1.3份,碳化铌0.73份,二硅化钼0.53份。 [0020] Example 4 one cardiovascular arterial stent comprising a plurality of said annular body and a plurality of connecting members for connecting the annular member, the connecting member and the annular member is coated with a coating, cyclic a plurality of beams having triangular ribs uniformly distributed along the ring, the connecting member having a V-shaped connecting rod, the connecting rod having an end portion of copper-based alloy material for the turnbuckle, the connecting member connecting annular body which elemental composition (mass percentage): Cr 12.4%, Sn 4.3%, Zn 2.2%, Mo 0.57%, Mg 0.36%, Fe 0.18%, Ni0.089%, B 0.088%, Nd 0.057%, Ga 0.046%, 0.029% & square, 〇1 balance, the annular body is a titanium-based alloy material having elemental composition (percent by mass): Cr 7.7%, Si 4.4%, Zn 5.3%, B 1.4%, V 0.88%, Zr 0.77%, Bi 0.24 %, Ag 0.23%, Mg0.12%, La 0.082%, Y 0.041%, Nb0.063%, the balance being Ti, a coating comprising: 28 parts of boron carbide, 14 parts of nickel oxide, 7.8 parts of calcium hexaboride, 1.3 parts of aluminum oxide, 0.73 parts of niobium carbide, 0.53 parts of molybdenum disilicide.

[0021] 实施例5一种心血管动脉支架,包括多个环状体和所述多个用于连接所述环状体的连接部件, 连接部件和环状体包覆有涂层,环状体具有多个沿环均匀分布的三角形筋梁,连接部件具有V形连接杆,连接杆端部具有用于连接环状体的螺旋扣,连接部件为铜基合金材料,其元素组成为(质量百分比):Cr 12.9%,Sn 4.8%,Zn 2.6%, Mo 0.54%, Mg 0.38%,Fe 0.18%,Ni0.089%, B 0.087%,Nd 0.056%,Ga 0.047%, 〇&0.029%,余量为〇1,环状体为钛基合金材料,其元素组成为(质量百分比):Cr 7.8%,Si 4.4%,Zn 5.3%,B 1.9%,V 0.87%, Zr 0.76%, Bi 0.27%, Ag 0.23%,Mg0.18%, La 0.087%, Y 0.048%, 他0.067%,余量为11,涂层包括:碳化硼23份,氧化镍18份,六硼化钙7.8份,氧化铝1.4份,碳化铌0.78份,二硅化钼0.53份。 [0021] Example 5 one cardiovascular arterial stent comprising a plurality of said annular body and a plurality of connecting members for connecting the annular member, the connecting member and the annular member is coated with a coating, cyclic a plurality of beams having triangular ribs uniformly distributed along the ring, the connecting member having a V-shaped connecting rod, the connecting rod having an end portion of copper-based alloy material for the turnbuckle, the connecting member connecting annular body which elemental composition (mass percentage): Cr 12.9%, Sn 4.8%, Zn 2.6%, Mo 0.54%, Mg 0.38%, Fe 0.18%, Ni0.089%, B 0.087%, Nd 0.056%, Ga 0.047%, 0.029% & square, 〇1 balance, the annular body is a titanium-based alloy material having elemental composition (percent by mass): Cr 7.8%, Si 4.4%, Zn 5.3%, B 1.9%, V 0.87%, Zr 0.76%, Bi 0.27 %, Ag 0.23%, Mg0.18%, La 0.087%, Y 0.048%, 0.067% he and the balance of 11, the coating comprising: 23 parts of boron carbide, 18 parts of nickel oxide, 7.8 parts of calcium hexaboride oxide 1.4 parts of aluminum, niobium carbide, 0.78 parts, 0.53 parts of molybdenum disilicide.

Claims (10)

  1. 1.一种心血管动脉支架,包括多个环状体和所述多个用于连接所述环状体的连接部件,连接部件和环状体包覆有涂层,环状体具有多个沿环均匀分布的三角形筋梁,连接部件具有V形连接杆,连接杆端部具有用于连接环状体的螺旋扣,连接部件为铜基合金材料,其元素组成为(质量百分比):〇12-13%,3114-5%,2112-3%, Mo 0.5-0.6%, Mg 0.3-0.4%,Fe 0.1-0.2%,N1.08-0.09%, B 0.08-0.09%,Nd 0.05-0 • 06%,Ga 0 • 04-0 • 05%,CaO • 02-0 • 03%,余量为Cu,环状体为钛基合金材料,其元素组成为(质量百分比):Cr 7-8%,Si 4-5%,Zn 5-6%,B 1-2%,V 0.8-0.9%, Zr 0.7-0.8%, Bi 0.2-0.3%, Ag 0.2-0.3%,Mg0.1-0.2%, La 0.08-0.09%,Y 0.04-0.05%,Nb0.06-0.07%,余量为Ti,涂层包括以下质量份数组分:碳化硼20-30份,氧化镍10-20份,六硼化钙7-8份,氧化铝1 -2份,碳化铌0.7-0.8份,二硅化钼0.5-0.6份。 An arterial cardiovascular stent, comprising a plurality of said annular body and a plurality of connecting members for connecting the annular member, the connecting member and the annular member is coated with a coating having a plurality of annular body triangular reinforced beam evenly distributed around the ring, the connecting member having a V-shaped connecting rod, the connecting rod having an end portion of copper-based alloy material for the turnbuckle, the connecting member connecting annular body which elemental composition (percentage by mass): square 12-13%, 3114-5%, 2112-3%, Mo 0.5-0.6%, Mg 0.3-0.4%, Fe 0.1-0.2%, N1.08-0.09%, B 0.08-0.09%, Nd 0.05-0 • 06%, Ga 0 • 04-0 • 05%, CaO • 02-0 • 03%, the balance is Cu, the annular body is a titanium-based alloy material having elemental composition (percent by mass): Cr 7-8 %, Si 4-5%, Zn 5-6%, B 1-2%, V 0.8-0.9%, Zr 0.7-0.8%, Bi 0.2-0.3%, Ag 0.2-0.3%, Mg0.1-0.2% , La 0.08-0.09%, Y 0.04-0.05%, Nb0.06-0.07%, the balance being Ti, a coating mass comprising the components parts: 20-30 parts of boron carbide, nickel oxide, 10-20 parts, six boron 7-8 parts of calcium, 1-2 parts of alumina, 0.7-0.8 parts of niobium carbide, molybdenum disilicide 0.5-0.6 parts.
  2. 2.如权利要求1所述的一种心血管动脉支架,连接部件为铜基合金材料,其元素组成为(质量百分比):Cr 12%,Sn 4%,Zn 2%,Mo 0.5%,Mg 0.3%,Fe 0.1%,Ni0.08%,B 0.08%,Nd 0.05%,Ga 0.04%,Ca0.02%,余量为Cu。 2. An arterial cardiovascular stent according to claim 1, the connecting member is a copper-based alloy material having elemental composition (percent by mass): Cr 12%, Sn 4%, Zn 2%, Mo 0.5%, Mg 0.3%, Fe 0.1%, Ni0.08%, B 0.08%, Nd 0.05%, Ga 0.04%, Ca0.02%, the balance being Cu.
  3. 3.如权利要求1所述的一种心血管动脉支架,连接部件为铜基合金材料,其元素组成为(质量百分比):Cr 12.5%,Sn 4.5%,Zn 2.5%,Mo 0.55%,Mg 0.35%,Fe 0.15%, Ni0.085%,B 0.085%,Nd 0.055%,Ga 0.045%,Ca0.025%,余量为Cu。 3. An arterial cardiovascular stent according to claim 1, the connecting member is a copper-based alloy material having elemental composition (percent by mass): Cr 12.5%, Sn 4.5%, Zn 2.5%, Mo 0.55%, Mg 0.35%, Fe 0.15%, Ni0.085%, B 0.085%, Nd 0.055%, Ga 0.045%, Ca0.025%, the balance being Cu.
  4. 4.如权利要求1所述的一种心血管动脉支架,连接部件为铜基合金材料,其元素组成为(质量百分比):Cr 13%,Sn 5%,Zn 3%,Mo 0.6%,Mg 0.4%,Fe 0.2%,Ni 0.09%,B 0.09%,Nd 0.06%,Ga 0.05%,Ca 0.03%,余量为Cu。 4. An arterial cardiovascular stent according to claim 1, the connecting member is a copper-based alloy material having elemental composition (percent by mass): Cr 13%, Sn 5%, Zn 3%, Mo 0.6%, Mg 0.4%, Fe 0.2%, Ni 0.09%, B 0.09%, Nd 0.06%, Ga 0.05%, Ca 0.03%, the balance being Cu.
  5. 5.如权利要求1所述的一种心血管动脉支架,环状体为钛基合金材料,其元素组成为(质量百分比):Cr 7%,Si 4%,Zn 5%,B 1%,V 0.8%,Zr 0.7%,Bi 0.2%,Ag 0.2%, Mg0.l%,La 0.08%,Y 0.04%,Nb0.06%,余量为Ti。 5. An arterial cardiovascular stents, the annular body as claimed in claim 1, a titanium-based alloy material having elemental composition (percent by mass): Cr 7%, Si 4%, Zn 5%, B 1%, V 0.8%, Zr 0.7%, Bi 0.2%, Ag 0.2%, Mg0.l%, La 0.08%, Y 0.04%, Nb0.06%, the balance is Ti.
  6. 6.如权利要求1所述的一种心血管动脉支架,环状体为钛基合金材料,其元素组成为(质量百分比):Cr 8%,Si 5%,Zn 6%,B 2%,V 0.9%,Zr 0.8%,Bi 0.3%,Ag 0.3%,Mg 0.2%,La 0.09%,Y 0.05%,Nb 0.07%,余量为Ti〇 6. An arterial cardiovascular stent according to claim 1, the annular body is a titanium-based alloy material having elemental composition (percent by mass): Cr 8%, Si 5%, Zn 6%, B 2%, V 0.9%, Zr 0.8%, Bi 0.3%, Ag 0.3%, Mg 0.2%, La 0.09%, Y 0.05%, Nb 0.07%, the balance being Ti〇
  7. 7.如权利要求1所述的一种心血管动脉支架,环状体为钛基合金材料,其元素组成为(质量百分比):Cr 7.5%,Si 4.5%,Zn 5.5%,B 1.5%,V 0.85%,Zr 0.75%,Bi 0.25%,Ag 0.25%,Mg0.15%,La 0.085%,Y 0.045%,Nb0.065%,余量为Ti。 7. An arterial cardiovascular stent according to claim 1, the annular body is a titanium-based alloy material having elemental composition (percent by mass): Cr 7.5%, Si 4.5%, Zn 5.5%, B 1.5%, V 0.85%, Zr 0.75%, Bi 0.25%, Ag 0.25%, Mg0.15%, La 0.085%, Y 0.045%, Nb0.065%, the balance is Ti.
  8. 8.如权利要求1所述的一种心血管动脉支架,涂层包括:碳化硼20份,氧化镍10份,六硼化钙7份,氧化铝1份,碳化铌0.7份,二硅化钼0.5份。 8. An arterial cardiovascular stent according to claim 1, the coating comprising: 20 parts of boron carbide, 10 parts of nickel oxide, 7 parts of calcium hexaboride, 1 part of alumina, 0.7 parts of niobium carbide, molybdenum disilicide 0.5 parts.
  9. 9.如权利要求9所述的一种心血管动脉支架,涂层包括:碳化硼20份,氧化镍10份,六硼化钙7份,氧化铝1份,碳化铌0.7份,二硅化钼0.5份。 One cardiovascular artery stent as claimed in claim 9, the coating comprising: 20 parts of boron carbide, 10 parts of nickel oxide, 7 parts of calcium hexaboride, 1 part of alumina, 0.7 parts of niobium carbide, molybdenum disilicide 0.5 parts.
  10. 10.如权利要求1所述的一种心血管动脉支架,涂层包括:碳化硼25份,氧化镍15份,六硼化钙7.5份,氧化铝1.5份,碳化铌0.75份,二硅化钼0.55份。 One cardiovascular artery stent as claimed in claim 1, the coating comprising: 25 parts of boron oxide, 15 parts of nickel, 7.5 parts of calcium hexaboride, 1.5 parts alumina, 0.75 parts of niobium carbide, molybdenum disilicide 0.55 parts.
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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060265048A1 (en) * 2005-05-18 2006-11-23 Advanced Cardiovascular Systems, Inc. Polymeric stent patterns
CN101448534A (en) * 2006-05-17 2009-06-03 生物技术公司 Anisotropic nanoporous coatings for medical implants
CN201840555U (en) * 2010-03-10 2011-05-25 谢建 Vessel stent being beneficial to being pressed and held
CN104127268A (en) * 2014-06-16 2014-11-05 苏州固基电子科技有限公司 Vascular stent firm in supporting

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060265048A1 (en) * 2005-05-18 2006-11-23 Advanced Cardiovascular Systems, Inc. Polymeric stent patterns
CN101448534A (en) * 2006-05-17 2009-06-03 生物技术公司 Anisotropic nanoporous coatings for medical implants
CN201840555U (en) * 2010-03-10 2011-05-25 谢建 Vessel stent being beneficial to being pressed and held
CN104127268A (en) * 2014-06-16 2014-11-05 苏州固基电子科技有限公司 Vascular stent firm in supporting

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