CN105943839A

CN105943839A - Preparation method for traditional Chinese medicinal composition for treating liver depression and phlegm heat type chronic pharyngitis and composition

Info

Publication number: CN105943839A
Application number: CN201610547846.6A
Authority: CN
Inventors: 杨高林
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-07-12
Filing date: 2016-07-12
Publication date: 2016-09-21

Abstract

The invention discloses a preparation method for a traditional Chinese medicinal composition for treating liver depression and phlegm heat type chronic pharyngitis. Orally taken medicaments are pills, and the preparation method comprises the following steps: a, extracting crude medicaments to obtain component 1 by virtue of ethanol; b, decocting dregs obtained by ethanol extraction twice with water, and mixing and concentrating extracting solutions to obtain component 2; c, mixing and concentrating component 1 and component 2 to obtain extract, and adding starch or dextrin to prepare the pills. In step a, all the crude medicaments are chopped and impregnated in a covered stainless steel barrel, a 70 percent ethanol solution is added of which the mass is 0.8 to 1 time that of coarse particles for uniform stirring, and the mixture is placed for more than 1 hour in a wet and closed environment to be completely swelled. The traditional Chinese medicinal composition has the effects of soothing the liver, promoting the circulation of qi, removing stasis, eliminating stagnation, regulating qi-flowing for strengthening spleen, tonifying the kidney and moistening lung to treat both symptoms and root causes, and keeps effective when being clinically used.

Description

The Chinese medicinal preparation method for the treatment of phlegm stagnation pattern of fever chronic pharyngitis and combinations thereof thing

Technical field

The present invention relates to containing the pharmaceutical product deriving from plant, animal or mineral component, particularly to A kind of Chinese medicine composition treating phlegm stagnation pattern of fever chronic pharyngitis and preparation method thereof.

Background technology

When patients with chronic pharyngitis is gone to a doctor, the usually pharyngeal discomfort of main suit, itching throat is coughed, pharyngeal if any thing resistance, That tells does not goes out, and can not swallow, and the most frequently sends the sound of " noise made in coughing or vomiting of uttering a sound or a word ".Here it is the traditional Chinese medical science is referred to as " slow larynx Numbness " disease.This disease mostly occurs in middle age, and the course of disease is long, and symptom is more, recurrent exerbation, no Easily cure.The traditional Chinese medical science thinks the door that throat is lung stomach, if any accumulated heat in the lung and stomach, and burning hot upper inflammation, stifling throat； Or because of deficiency of kidney-YIN, hyperactivity of deficient fire, decoct the body fluid that burns, all can cause pharyngeal chronic congestion, mucosa is dried, pharynx Larynx loses supports and falls ill.The traditional Chinese medical science of having a talk below is how to treat chronic pharyngitis.

One, prevention of diseae

1. having regular daily life: keeping room air fresh is one of effective measures preventing and treating chronic pharyngitis.Also should in room Maintain suitable temperature and humidity.Air is dried and supercool, overheated, overly moist all can affect pharyngeal mucosa Defensive enginery, causes pharyngeal paraesthesia, with the passing of time causes chronic pharyngitis pathological changes.Morning to be accomplished, After meal and gargle, brush teeth before sleep, keep oral cavity cleaning.

2. adjusting diet: diet is the lightest, food delicious food savoury and oil squeeze the food of food less.Season in spring and autumn eats one more There is the food of sour sweet YIN nourishing a bit, such as Fructus Citri tangerinae, Fructus Canarii albi, pear, Fructus Canarii and fresh vegetables etc..

3. move health preserving: strengthen taking exercise, health invigorating, reach the purpose of " in healthy energy is deposited, heresy can not be done ".Subtract Few tobacco and wine and dust etc. stimulate, and correct the bad habits such as mouth breathing.Also to avoid excessively pronouncing.

4. preventing diseases caused by external factors: active prevention respiratory tract infection, actively preventing and treating mouth and nose and laryngopharyngeal diseases.

Two, preventing exacerbation after being taken ill

Chronic pharyngitis can be individually present, it is possible to is secondary to other position inflammation perhaps many whole bodies diseases of upper respiratory tract Sick.Chronic pharyngitis is controlled not in time, also can cause general malaise, even hoarseness.Therefore must promptly treat. The traditional Chinese medical science can be divided into the different pattern of syndrome such as accumulated heat in the lung and stomach, phlegm stagnation heat, YIN-deficiency of the lung and kidney according to its clinical manifestation.This Disease wants determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs:

(1) accumulated heat in the lung and stomach, clinical syndrome: dry mouth and tougue, discomfort in the throat, dry cough expectorant is few and yellow, pharyngeal Mucosa is red red, yellow urine, big dry stool, red tongue with yellow fur, rapid pulse or reality.Method for the treatment of: lung heat clearing gastric heat, expectorant Sore-throat relieving.Prescription: powder for clearing lung-heat closes QINGWEI SAN plus-minus.

(2) phlegm stagnation heat, clinical syndrome: parched throat hypodynia, foreign body in pharynx sense is obvious, and that tells does not goes out, and gulps down Not under, when feelings will is smooth more so, being irritable and getting angry easily, the breast side of body is vexed swollen, swallows rear wall follicle hypertrophy, and stool is not Adjust, red tongue or light red, yellow and greasy fur, wiry and frequent pulse.Method for the treatment of: Shugan Qingre, reduce phlegm sore-throat relieving.Prescription: red Cape jasmine XIAOYAO POWDER is added and subtracted.

(3) YIN-deficiency of the lung and kidney, clinical syndrome: pharyngeal dry, scorching hot pain, the most heavier or pharyngeal Unfavorable, dry cough expectorant is few and thick, and pharyngeal mucosa is dark red, dysphoria with feverish sensation in the chest palms and soles, red tongue with a little fluid, thready and rapid pulse.Method for the treatment of: Nourishing lung and kidney, relieving sore-throat by clearing away heat.

Chronic simple pharyngitis is controlling various paathogenic factors, is keeping good living habit and apply various controlling Can alleviating after treatment until curing, otherwise delay may become chronic hypertrophic pharyngitis；Chronic hypertrophic is swallowed Scorching and atrophic or chronic pharyngitis sicca therapeutic effect is not good enough, and symptom is the most repeatedly；Chronic allergic Property pharyngitis depart from symptom after sensitinogen and can alleviate to disappearance；After chronic reflux pharyngitis controls gastroesophageal reflux Symptom can substantially be alleviated until curing.

Summary of the invention

The technical problem to be solved is, phlegm stagnation pattern of fever chronic pharyngitis, and clinical manifestation exists: Parched throat hypodynia, foreign body in pharynx sense is obvious, and that tells does not goes out, and can not swallow, when feelings will is not smooth more so, irritable Irritability, the breast side of body is vexed swollen, swallows rear wall follicle hypertrophy, defecates uncomfortable, red tongue or light red, yellow and greasy fur, stringy pulse Number.Method for the treatment of: Shugan Qingre, reduce phlegm sore-throat relieving.Doctor trained in Western medicine typically solves with chemicals, though there being certain curative effect, Instant effect, but easily have side effect in various degree or cause some complication；Chinese medicine product is then because of it Draw materials natural, safety good, low side effect, documents and materials are abundant, clinical efficacy is good and enjoys favor. But existing prescription specific aim is poor, it is impossible to fundamentally alleviate the symptom of chronic pharyngitis, and also have certain Side effect.Therefore, the Chinese medicine composition finding a kind of highly effective and safe becomes the urgent needs of people.

For solving these technical barriers, the invention provides a kind for the treatment of in phlegm stagnation pattern of fever chronic pharyngitis Drug composition, its described Chinese medicine composition is made up of with external used medicine endo-medicine, and endo-medicine can wrap Include the crude drug of following parts by weight: Cortex Moutan 10～20 parts, Exocarpium Citri Rubrum 10～20 parts, Radix Ophiopogonis 10～20 parts, Fructus Gardeniae 10～20 parts, Caulis Perillae 10～20 parts, the Radix Paeoniae Alba 10～20 parts, Radix Bupleuri 10～20 parts, Rhizoma Cyperi 10～ 20 parts, Radix Glycyrrhizae 10～20 parts, Radix Platycodonis 10～20 parts, Semen Oroxyli 10～20 parts, Poria 10～20 parts, know Female 10～20 parts, Fructus Trichosanthis 10～20 parts, Folium Eriobotryae 10～20 parts, Radix Trichosanthis 10～20 parts, Spica Prunellae 10～ 20 parts, Radix Scutellariae 10～20 parts.

Described external used medicine can include the crude drug of following parts by weight: watermelon crystal 10～20 parts, the Radix Angelicae Dahuricae 10～20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10～20 parts, Herba Menthae 10～20 parts, Borneolum Syntheticum 10～20 parts, Bombyx Batryticatus 10～20 parts, Fructus Momordicae 10～20 parts, Rhizoma Et Radix Notopterygii 10～20 parts, Folium Artemisiae Argyi 10～20 parts, Radix Clematidis 10～20 parts.

The Chinese medicine composition of described treatment phlegm stagnation pattern of fever chronic pharyngitis, its described endo-medicine can also wrap Include the crude drug of following parts by weight: Cortex Moutan 10～15 parts, Exocarpium Citri Rubrum 10～15 parts, Radix Ophiopogonis 10～15 parts, Fructus Gardeniae 10～15 parts, Caulis Perillae 10～15 parts, the Radix Paeoniae Alba 10～15 parts, Radix Bupleuri 10～15 parts, Rhizoma Cyperi 10～ 15 parts, Radix Glycyrrhizae 10～15 parts, Radix Platycodonis 10～15 parts, Semen Oroxyli 10～20 parts, Poria 10～20 parts, know Female 10～20 parts, Fructus Trichosanthis 10～20 parts, Folium Eriobotryae 10～20 parts, Radix Trichosanthis 10～20 parts, Spica Prunellae 10～ 20 parts, Radix Scutellariae 10～20 parts.

Described external used medicine can also include the crude drug of following parts by weight: watermelon crystal 10～15 parts, in vain The root of Dahurian angelica 10～15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10～15 parts, Herba Menthae 10～15 parts, Borneolum Syntheticum 10～15 parts, Bombyx Batryticatus 10～20 Part, Fructus Momordicae 10～20 parts, Rhizoma Et Radix Notopterygii 10～20 parts, Folium Artemisiae Argyi 10～20 parts, Radix Clematidis 10～20 parts.

The Chinese medicine composition of described treatment phlegm stagnation pattern of fever chronic pharyngitis, its described endo-medicine can also wrap Include the crude drug of following parts by weight: Cortex Moutan 10～20 parts, Periostracum Cicadae 10～20 parts, Radix Ophiopogonis 10～20 parts, Fructus Gardeniae 10～20 parts, Caulis Perillae 10～20 parts, the Radix Paeoniae Alba 10～20 parts, Radix Bupleuri 10～20 parts, Rhizoma Cyperi 10～ 20 parts, Radix Glycyrrhizae 10～20 parts, Radix Platycodonis 10～20 parts, Semen Oroxyli 10～15 parts, Poria 10～15 parts, know Female 10～15 parts, Fructus Trichosanthis 10～15 parts, Folium Eriobotryae 10～15 parts, Radix Trichosanthis 10～15 parts, Spica Prunellae 10～ 15 parts, Radix Scutellariae 10～15 parts.

Described external used medicine can also include the crude drug of following parts by weight: watermelon crystal 10～20 parts, in vain The root of Dahurian angelica 10～20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10～20 parts, Herba Menthae 10～20 parts, Borneolum Syntheticum 10～20 parts, Bombyx Batryticatus 10～ 15 parts, Fructus Momordicae 10～15 parts, Rhizoma Et Radix Notopterygii 10～15 parts, Folium Artemisiae Argyi 10～15 parts, Radix Clematidis 10～15 Part.

For solving above-mentioned technical problem, the present invention also provides for one and treats phlegm stagnation pattern of fever chronic pharyngitis Chinese medicine The preparation method of compositions, it is characterised in that described endo-medicine is that the preparation method of tablet includes following Step:

A. the extraction of raw material medicinal alcohol is taken, as component 1；

B. by stripped for ethanol medicinal residues soak by water 2 times, concentrated extracting solution is merged, as component 2；

C. by 2-in-1 for component 1 component and be condensed into extractum, add starch or dextrin is in harmonious proportion film-making.

In described step a, all crude drug can be shredded, be soaked and be placed in lid stainless steel cask, Adding 70% ethanol, quality is coarse grained 0.8-1 times, stirs, moistening airtight placement more than 1 hour, Make fully to expand；Filter plate gauze bag bottom percolator is wrapped up after paving again by the medicine after moistening expansion Sample is mixed pine and is done to dissipate, and then contains powder with rustless steel spoon, loads percolator uniformly, fills 10-12 cm thick, Even by T-bar pressure, then press aforesaid operations, loading in layer, suitably pressurize, medicated powder must not load Exceed 2/3 eminence of percolator；Medicated powder face upper cover rustless steel orifice plate fastens, and opens the blowing below percolator Valve, and put a container, then it is slowly added into 70% ethanol；Air between medicated powder powder to be discharged, And have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open Material valve carries out percolation, controls percolation speed and is generally 1000g medical material outflow per minute 2～3ml, and filtrate is put Enter in liquid container, and pour ethanol during emptying into liquid container；Percolate is merged and stands, stand standby With, as component 1.

In described step b, can above-mentioned stripped raw material residue be put in 10 times amount water, soak 1-2 Hour, heating extraction 2 times, each 1-2 hour, remove supernatant, united extraction liquid, 100-120 mesh filters, The ultrafiltration post ultrafiltration that molecular weight is 5000-10000 through damming again, ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C time 1.05 filtrate, as component 2.

In described step c, can put in economic benefits and social benefits vacuum concentrator mix 2-in-1 also to component 1 and component, First concentrating the filtrate to relative density when 80 DEG C is the concentrated solution of 1.32, sets to 0～5 DEG C of deepfreezes 24 hours； The filter aid kieselguhr adding 0.3% by cold preservation liquid, filters, and filtrate is inserted in economic benefits and social benefits vacuum concentrator again, dense It is reduced to every 1ml extractum Han 0.1g, then adds dextrin or starch tabletting, pack.

For solving above-mentioned technical problem, the present invention reoffers one and treats phlegm stagnation pattern of fever chronic pharyngitis Chinese medicine The preparation method of compositions, the external preparation of its described Chinese medicine composition is spray, preparation method be with Lower step:

A. take the Radix Angelicae Dahuricae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Menthae, Borneolum Syntheticum and the Rhizoma Et Radix Notopterygii way of distillation and be vaporized into crystallization, pulverize dusting cover Stand-by, as component 1；

B. by remaining raw material except watermelon crystal external ethanol extraction, concentrate, as component 2；

C. after being mixed with component 1 component 2 by watermelon crystal, solubilizer is in harmonious proportion, and sterilization loads aerosol apparatus.

In described step a, can first the crude drug Radix Angelicae Dahuricae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Menthae, Borneolum Syntheticum and Rhizoma Et Radix Notopterygii use water be steamed Gas method is distilled, and obtains crystal, then pulverizes, and crosses 100-120 mesh sieve, standby as component 1.

In described step b, can will put in 10 times amount ethanol except remaining crude drug of watermelon crystal, soak 1-2 hour, heating extraction 2 times, each 1-2 hour, remove supernatant, united extraction liquid, 100-120 mesh Filter, then the ultrafiltration post ultrafiltration that molecular weight is 5000-10000 through damming, ultrafiltrate concentrating under reduced pressure is the closeest The filtrate of 1.05 when degree is 80 DEG C, as component, as component 2；By in watermelon crystal and component 1 component 2, Stir, solubilizer, load in aerosol apparatus, owing to the present invention is without preservative, need cold preservation.

Chronic pharyngitis is a kind of commonly encountered diseases, and chronic pharyngitis is more common in adult, and child also may occur in which.Whole body Symptom is the most inconspicuous, based on local symptom.Various chronic pharyngitis symptom is substantially similar and varied, As pharyngeal sense of discomfort, foreign body sensation, pharyngeal secretions be difficult to bring up, pharyngeal gargalesthesia, burn feeling, dry sensation Or excitement, also can there is hypodynia sense.Phlegm stagnation pattern of fever chronic pharyngitis, clinical manifestation exists: parched throat hypodynia, Foreign body in pharynx sense is obvious, and that tells does not goes out, and can not swallow, and when feelings will is not smooth more so, being irritable and getting angry easily, breast is coerced Vexed swollen, swallow rear wall follicle hypertrophy, defecate uncomfortable, red tongue or light red, yellow and greasy fur, wiry and frequent pulse.Method for the treatment of: Shugan Qingre, reduce phlegm sore-throat relieving.Doctor trained in Western medicine typically solves with chemicals, though there being certain curative effect, and instant effect, But easily there is side effect in various degree or cause some complication；Chinese medicine product is then because of its sky of drawing materials So, safety side effect good, low, documents and materials are abundant, clinical efficacy is good and enjoys favor.The present invention Oral administration and externally amalgamation, Radix Curcumae, Caulis Perillae, Exocarpium Citri Rubrum dispersing the stagnated live-QI to relieve the stagnation of QI in soothing the liver sore-throat relieving soup side, circulation of qi promoting disappears Swollen, drying dampness to eliminate phlegm, regulating qi-flowing for strengthening spleen, with the trouble of eliminating phlegm-retention condensation；Folium Eriobotryae, Radix Scutellariae clearing away lung-heat and moistening for dryness, change Phlegm and relieving cough, purge heat pathogenic fire reducing, with the lung-fire of the clear part of the body cavity above the diaphragm housing the heart and lungs；Fructus Trichosanthis, Radix Trichosanthis kidney tonifying yin nourishing, alleviating distention in middle-JIAO regulates the flow of vital energy, The raw gold of lung moistening, with mutual generation between metal and water, links up up and down by lung kidney；Cortex Moutan, Bulbus Fritillariae Thunbergii blood circulation promoting and blood stasis dispelling, relieving restlessness is pacified God, heat clearing away eliminating stagnation, with stasis in the pharynx that disappears；Spica Prunellae, Fructus Gardeniae, the Bombyx Batryticatus pharyngeal follicle hypertrophy of dissipation；Fructus Citri tangerinae Stalk, Semen Oroxyli, mint phlegm and relieving cough, lung qi dispersing sore-throat relieving, with the up throat of priming.Entirely can soothing the liver circulation of qi promoting, Eliminating stasis and resolving masses, regulating qi-flowing for strengthening spleen, kidney tonifying lung moistening, so, then treating both the principal and secondary aspects of a disease, thus clinical with it, control repeatly repeatly Effect.

Detailed description of the invention

Chronic pharyngitis is for swallowing under mucosa, mucosa and adenoid chronic inflammatory disease.Diffusivity pharyngeal inflammation is normal A part for upper respiratory tract chronic inflammatory disease；Limitation pharyngeal inflammation mostly then is pharynx lymphoid tissue inflammation.This Sick common in clinic, the course of disease is long, the easy recurrent exerbation of symptom.From pathology, chronic pharyngitis can be divided For following 5 classes:

1. chronic simple pharyngitis

This type more typically, shows as pharyngeal mucosa chronic congestion.Pathological changes is concentrated mainly on pharyngeal mucosa Layer, has more lymphoid tissue to infiltrate, it is possible to see leukocyte and plasmocyte infiltrating around its blood vessel.Mucosa and Connective tissue proliferation under mucosa, can be loose with mucous gland, glandular secretion hyperfunctioning, and mucilage secretion increases Many and more sticky.

2. chronic hypertrophic pharyngitis

Also known as chronic particulate-pharyngitis and lateral pharyngitis, chronic simple pharyngitis protracted course of disease can form chronic fertilizer Thickness pharyngitis, this type is the most common in clinic.Pharyngeal mucous layer hyperemia thickens, mucosa and mucosa Under have connective tissue and lymphadenosis widely, the lymphadenosis projection around mucous gland, Performance pharynx rear wall multiple graininess lymph follicle, also can merge by multiple lymph follicles in chronic congestion shape It is integrated.Inflammatory exudate in mucous gland can be closed wherein, is formed at the top of lymph granule protuberance Cryptomere white point, visible yellow-white exudate during ulceration.This kind of chronic pharyngitis often involves lateral pharyngeal band lymphoid tissue, Make its hypertrophy plump, in streak.

3. atrophic and pharyngitis sicca

In clinic more rare.Their early stage mucous gland secretion reduce, secretions stiff and be dried.Continue because of glutinous Film lower floor chronic inflammatory disease, gradually sends out vitalization and contraction, compressing body of gland and blood vessel, makes glandular secretion reduce And malnutrition, cause the gradually atrophy of mucosa and Submucosa thinning.Dry crusts or pus crusts can be had on pharynx rear wall Attachment, generally entails stink.

4. chronic anaphylaxis pharyngitis

Also known as chronic allergia pharyngitis.For betiding the I allergic reaction type mediated by IgE of pharyngeal mucosa. Allergen stimulates pharyngeal mucosa, makes the plasma cell of synthesis IgM be converted into the plasma cell of synthesis IgE, and IgE is again It is attached to mastocyte, basophil cellular surface, makes pharyngeal mucosa be in sensitization.When identical After allergen contacts body again, allergen is combined with the IgE of medium cell surface, causes medium cell Retting conditions, release includes the multiple inflammatory mediator such as histamine, synthesis of prostaglandins, blood capillary can be caused to expand Open, vascular permeability increases, glandular secretion increases, and causes allergic reaction.And related allergy is former mainly Caused allergic reaction by Complement C_3, C4 approach.Chronic anaphylaxis pharyngitis occurs together in whole body allergia disease more Disease or allergic rhinitis, also can individually fall ill.Seasonal chronic anaphylaxis pharyngitis, its symptom can have season Property change.As to food anaphylaxis, the related symptoms of chronic pharyngitis can occur on the feed after sensitization food.

5. chronic reflux pharyngitis

Relevant to gastroesophageal reflux.Gastric juice is due to the pharyngeal mucosa of gastroesophageal reflux coup injury or by nerve Reflection causes the chronic inflammatory disease under pharyngeal mucosa and mucosa.

Chronic pharyngitis is more common in adult, and child also may occur in which.General Symptoms is the most inconspicuous, with local disease Shape is main.Various chronic pharyngitis symptom is substantially similar and varied, as pharyngeal sense of discomfort, foreign body sensation, Pharyngeal secretions is difficult to bring up, pharyngeal gargalesthesia, burn feeling, dry sensation or excitement, also can have hypodynia sense. Due to pharynx rear wall generally cause more sticky secretions to adhere to because of pharyngeal chronic inflammatory disease, and due to nose, nasal sinuses, Nasopharynx pathological changes causes mouth breathing at night, irritable cough occurs and feel sick when Chang Chen rises.Due to pharynx Portion's foreign body sensation can behave as frequently swallowing.Pharyngeal secretions is few and is difficult to expectoration person and often shows as habitually Dry cough and expectoration action of clearing one's throat, can cause pharyngeal mucosa hemorrhage if firmly coughing or clearing one's throat, and causes point Band blood in secretion.

Treatment: 1. removing the cause of disease, wine for giving off smoking, active treatment causes protopathy (the acute pharynx of chronic pharyngitis Scorching, nose and nasopharynx part chronic inflammatory disease, reflux gastroesophageal disorder, improve work and living environment).2. Lifestyle change, carries out the psychology that suitable physical training, normal work and rest, light diet, holding are good State is to improve pharyngeal mucosa local function state by strengthening self overall immune functional state.3. innings Portion's treatment (1) chronic simple pharyngitis, commonly uses the rinsing the mouth such as compound recipe Borax, furacilin solution, keeps Oral cavity, pharyngeal cleaning；Or buccal iodine lozenge, Mint throat lozenge etc. treat the lozenge of pharyngeal chronic inflammatory disease； Chinese medicine preparation as also there being certain curative effect to chronic pharyngitis；The available glycerinum iodi compositum in local, 5% silver nitrate molten Liquid or 10% argyrol solution smear pharyngeal, have convergence and antiinflammation；Ultrasonic atomizatio can be alleviated The symptom of chronic pharyngitis；Typically need not antibiotic therapy.

Radix Curcumae, Caulis Perillae, Exocarpium Citri Rubrum dispersing the stagnated live-QI to relieve the stagnation of QI, relieving distension by promoting circulation of QI, dampness in the present invention soothing the liver sore-throat relieving soup side Reducing phlegm, regulating qi-flowing for strengthening spleen, with the trouble of eliminating phlegm-retention condensation；Folium Eriobotryae, Radix Scutellariae clearing away lung-heat and moistening for dryness, preventing phlegm from forming and stopping coughing, Purge heat pathogenic fire reducing, with the lung-fire of the clear part of the body cavity above the diaphragm housing the heart and lungs；Fructus Trichosanthis, Radix Trichosanthis kidney tonifying yin nourishing, alleviating distention in middle-JIAO regulates the flow of vital energy, the raw gold of lung moistening, With mutual generation between metal and water, lung kidney is linked up up and down；Cortex Moutan, Bulbus Fritillariae Thunbergii blood circulation promoting and blood stasis dispelling, relieving restlessness calms the nerves, and heat clearing away dissipates Knot, with stasis in the pharynx that disappears；Spica Prunellae, Fructus Gardeniae, the Bombyx Batryticatus pharyngeal follicle hypertrophy of dissipation；Radix Platycodonis, Semen Oroxyli, Mint phlegm and relieving cough, lung qi dispersing sore-throat relieving, with the up throat of priming.Entirely can soothing the liver circulation of qi promoting, eliminating stasis and resolving masses, Regulating qi-flowing for strengthening spleen, kidney tonifying lung moistening, so, then treating both the principal and secondary aspects of a disease, thus clinical with it, control repeatly and imitate repeatly.

The Radix Paeoniae Alba enters liver, spleen channel, nourishing blood to suppress the hyperactive liver, and slow middle pain relieving, yin fluid astringing receives antiperspirant.Control the chest and abdomen pain over the hypochondriac region, Dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia, and married woman's blood closes obstructed, Repercussive blood, can lose pus, benefit woman's blood." Japan hanako materia medica ": control wind, mend labor, all diseases of main woman, And antenatal after all diseases, Tong Yueshui, bring down a fever, relieving restlessness, QI invigorating, the hot disease of sky row, pestilence miasma, mania and irritation, married woman Blood is transported, and hemorrhoidal hamorrhage, rushes down blood, hemorrhoid complicated by anal fistula.Carbuncle on the back, skin ulcer scabies, headache, improving eyesight, conjunctival congestion exerts meat.Redness of the skin or complexion person Many QI invigorating, white person controls blood.

The Rhizoma Anemarrhenae, Classification system: Anemarrhena asphodeloides Bunge, is also RHIZOMA ANEMARRHENAE with peet, for many years The dry root stock of raw herbaceous plant this kind is famous Chinese medicine, property bitter cold, have nourishing YIN to lower pathogenic fire, moisturize laxation, The effect of profit defecation.Belong to gunpowder under heat clearing away, cure mainly: epidemic febrile disease, high hot excessive thirst, cough and asthma, cough caused by dryness, Constipation, osteopyrexia and fever, restlessness of asrhenia type and insomnia, stranguria with turbid discharge of quenching one's thirst.There is dividing of " RHIZOMA ANEMARRHENAE with peet " and " unpeeled RHIZOMA ANEMARRHENAE ".The most main Want producing region in Hebei.Chinese medicine is called: rabbit Herba Leptochloae Chinensis, great Lu water, Ma Macao, garlic clove grass, furuncle Root, L.Lucidus Turcz. etc..

Radix Ophiopogonis, " book on Chinese herbal medicine lease making " claims that Radix Ophiopogonis, " hardship sweet, micro-, was slightly cold.Lung moistening clears away heart-fire, purge heat promote the production of body fluid, Reduce phlegm preventing or arresting vomiting, control row water of coughing "." Records of Tradition Chinese and Western Medicine in Combination " says it: " can enter stomach with nourishing the stomach liquid, appetizing Feed, spleen is scattered is skillful in lung, Dingchuan relieving coughing to help more to enter spleen." traditional Chinese medical science thinks, Radix Ophiopogonis sweet in the mouth, micro-hardship, Cold nature, returns stomach, lung, heart channel, has nourishing YIN and moistening the lung, reinforcing stomach reg fluid, the effect of the relieving restlessness that clears away heart-fire, is used for Dryness of the lung dry cough, deficiency of YIN consumptive disease are coughed, sore throat pharyngalgia, Tianjin wound are thirsty, interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine just Secret disease such as grade.Modern pharmacological research also indicates that, Radix Ophiopogonis mainly containing dwarf lilyturf glycosides, steroidal saponin, alkaloid, Sitosterol, glucose, aminoacid, vitamin etc., have resisting fatigue, remove free radical, raising cell Immunologic function and hypoglycemic effect.It addition, have Radix Ophiopogonis calmness, hypnosis, resist myocardial ischemia, the anti-heart Restrain the effects such as not normal, antitumor, especially enhancement senior health and fitness is had many-sided effect.

Pseudobulbus Bletillae (Rhizoma Bletillae) property is bitter, sweet, puckery, is slightly cold.Return lung, liver, stomach warp.Function cures mainly astringing to arrest bleeding, detumescence Granulation promoting.Spit blood for hemoptysis, traumatic hemorrhage, sore swollen toxin, chapped skin；Pulmonary tuberculosis hemoptysis, ulcer Sick hemorrhage.Shennong's Herbal: " main carbuncle, malignant boil, lose cellulitis, the dead flesh of impairment of YIN, pathogen in stomach "； Compendium of Material Medica: " abnormal smells from the patient (root) is bitter, flat, nontoxic.

Folium Eriobotryae all can be gathered the whole year.Its cold nature, bitter in the mouth, have effect of clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI, It is usually used in treating cough due to lung-heat, QI rising in reverse order dyspnea with rapid respiration, gastric heat vomiting, the diseases such as dysphoria with smothery sensation is thirsty.Clearing away lung-heat to relieve cough, Stopping nausea and vomiting by lowering the adverse flow of QI.Cough due to lung-heat, QI rising in reverse order dyspnea with rapid respiration, gastropyretic vomiting, hiccup.Xerostomia can be treated quench one's thirst, lung Wind acne vulgaris, acne." not Lu ": " main soldier is more than, the therapeutic method to keep the adverse QI flowing downwards." " Treatise on Dietetic Therapy ": " liquor is drunk, Main thirsty disease, controls lung qi cough due to heat and lung-wind syndrome skin ulcer, skin ulcer on breast, face." " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " cough-relieving is coughed, is disappeared Expectorant Dingchuan, can break expectorant silk, changes pertinacious phlegm, dissipates to shout and breathes heavily, only tachypnea.″

Rhizoma Et Radix Notopterygii, another name Qiang is blue or green, protect Qiang envoy, recklessly king envoy, Qiang is sliding, move back wind envoy, black powder, Latin Literary fame Notopterygium incisum. Umbelliferae, Notopterygium plant, Chinese medicine cures mainly: warm in nature, dispelling cold and dampness, For affection of exogenous wind-cold, have a headache lossless, cold-damp numbness, upper limb rheumatalgia.Dissipate exterior cold；Wind-damp dispelling；Li Guan Joint；Pain relieving.Main affection of exogenous wind-cold；Have a headache lossless；Edema due to wind pathogen edema；Sore swollen toxin.For impotence and seminal emission, Enuresis frequent micturition, chills and pain of the waist and kness, suffer from a deficiency of the kidney and breathe heavily, Diarrhoea；External curing vitiligo, alopecia areata.Induce sweat scattered Cold, expelling wind and dampness, pain relieving.Property of medicine opinion ": " control harmful wind, aphonia in silence, blood leprosy of itching more, hands and feet caused by paralysis, The askew heresy of actinal surface, insensitive impediment all over." " Japan hanako materia medica ": " controls a wind cutting gas, muscles and bones fist contraction, extremity Thin bad, the head rotation red pain of eyes and fullness in the epigastrium especially referring to the abcess of the abdomen in ancient times aqueous vapor, five kinds of strain and seven kinds of impairment, deficient cold air, joint ache, tonneau five Dirty.″

Folium Artemisiae Argyi is pungent, bitter, temperature.Gui Jing returns liver,spleen,kidney warp.Effect warming the meridian for stopping bleeding, dispersing cold for relieving pain；Outward Use removing dampness to relieve itching.Cure mainly for spitting blood, epistaxis, metrorrhagia, menorrhagia, vaginal bleeding during pregnancy hematochezia, few abdomen cold type of pain, Coldness and unbalance in meridians, cold womb is infertile；External treatment skin pruritus.Vinegar Chinese mugwort charcoal warming the meridian for stopping bleeding is hemorrhage for deficient cold type. Compendium of Material Medica: warming middle-JIAO, by cold, dehumidifying." book on Chinese herbal medicine is looked for the truth ": specially enter liver spleen.Double enter kidney." this Grass is from new ": by cold-damp.Warm uterus.Only all blood.Warming middle-JIAO dissipating depression of QI.Regulating menstruation is antiabortive.

Cortex Lycii, another name: Chinese wolfberry skin, for Solanaceae, Lycium, is Fructus Lycii Lycium chinense Mill. Root bark.Can be used as medicine, have and bring down a fever except the effect of steaming, removing heat from blood is except effects such as steaming, lung heat clearing pathogenic fire reducing.

Cortex Moutan, has another name called Cortex Moutan, Chinese medicine name.It is dried root bark for ranunculaceae peony.Originate in Anhui, The ground such as Shandong.Excavate root autumn, remove radicula, strip root bark, dry.Life is used or is fried and uses." this Grass detailed outline ": " nourishing YIN to lower pathogenic fire solves speckle poison, throat, diuresis stasis.Descendant is specially to control with yellow tiller Xiang Huo, does not knows that the merit of Cortex Moutan more wins also.Red colored person profit, the person of spending in vain mends, and people the most seldom realizes, and preferably distinguishes it.” Modern study, contained paeonol and glucosides constituents in addition thereof all have antiinflammatory action；The methanol of Cortex Moutan Extract has suppression Platelet；Paeonol has the maincenters such as calmness, cooling, antipyretic, analgesia, spasmolytic Inhibitory action and atherosclerosis, diuresis, antiulcer etc. act on.

Radix Clematidis belongs to medicinal plants, and medical material Ji Yuan source is more, " Kaibao Bencao ", " Bencao Tujing ", The Radix Clematidis that herbal for Relief of Famines etc. are contained, for goatweed；The Radix Clematidis that " the southern regions of the Yunnan Province book on Chinese herbal medicine " is contained, Be feverfew, and use now mostly be " China book on Chinese herbal medicine " contained cohosh Radix Clematidis, cotton-wool Radix clematidis floridae, northeast clematis.Domestic distributed more widely, its root and stem be used as medicine have wind-damp dispelling, the meridian dredging, Disappear effect of bone stalk.In modern clinic is put into practice, its new purposes is constantly found, as treated cholelithiasis, Calcanean spur, chronic pharyngitis, the esophageal carcinoma etc..Expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, dissipate the hypochondriac lump. Cure mainly gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, knee joint cold type of pain, muscle arteries and veins contracture, joint stuffiness, tinea pedis, Malaria, lump in the abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat swallow.Tang Materia Medica: waist, kidney, foot Knee joint, accumulation, all cold diseases of enteral, be not recovered, the effect of clothes." Kaibao Bencao ": main all wind, Xuan Tong Five hide, and cold stagnant in removing abdomen, septum cordis expectorant water amasss for a long time, and lump in the abdomen Xuan tinea air parcel, bladder place pus aversion to water, waist knee joint is cold Pain and treatment injured.

Its root of Radix Platycodonis can be used as medicine, and has the effects such as eliminating phlegm and stopping cough, lung qi dispersing, evacuation of pus, traditional Chinese medical science common medicine.In The Northeast of state is often pickled as brined vegetable, is used in the Korea peninsula make Pickles.Lung qi dispersing, sore-throat relieving, dispel Expectorant, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection pus becomes. Antiinflammatory action: thick kikyosaponin has antiinflammatory action, gavages the dosage of 1/10～1/5 median lethal dose(LD 50) to greatly Mus hind leg chondrus ocellatus Holmes colloidality swelling of the feet and acetic acid swelling all have antiphlogistic effects.Gavage is less than 1/10 median lethal The dosage of amount, every day 1 time, successive administration, also there is significant inhibitory action to rat granuloma is swollen, and The most effective to rat assist agent arthritis.This kind of preparation can also reduce anaphylaxis, the blood capillary of mice Permeability.The mouse writhing that lumbar injection kikyosaponin causes reacts and Abdominal effusion, the same Saponin of gavage Suppression can be produced.Radix Platycodonis is without direct antibacterial action, but its water extract can strengthen macrophage phagocytic function, Strengthen the sterilizing power of neutrophilic leukocyte.Improve the activity of lysozyme.

Fructus Gardeniae (formal name used at school: Gardenia jasminoides Ellis) is called: Yellow Fructus Gardeniae, Fructus Gardeniae, white toad, It it is the fruit of Maguireothamnus speciosus Fructus Gardeniae.The fruit of Fructus Gardeniae is Chinese medicine, belongs to the 1st batch of medicine that Ministry of Public Health is promulgated Eat dual-purpose resource, have hepatoprotective, function of gallbladder promoting, blood pressure lowering, calmness, stop blooding, the effect such as detumescence.At TCM Bed is usually used in treating the diseases such as icterohepatitis, bruise, hypertension, diabetes.

Radix Glycyrrhizae is used for insufficiency of heart-QI, severe palpitation, irregularly intermittent and regularly intermittent pulse, and deficiency of spleen-QI and stomach-QI, fatigue and weakness etc..Before Person, normal and Ramulus Cinnamomi compatibility, such as Ramuli Cinnamomi and Glycyrrhizae Decoction, zhigancao decoction.The latter, is often equal to Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae With, such as ball etc. in decoction of four noble drugs, reason.For ulcer sores, laryngopharynx swelling and pain etc..Can be alone, for oral administration or External application, or compatibility application.Ulcer sores, is often equal to use with Flos Lonicerae, Fructus Forsythiae, play altogether heat-clearing and toxic substances removing it Merit, such as Xian fang Huoming Yin.Laryngopharynx swelling and pain, the normal and same use of Radix Platycodonis, such as Radix Platycodonis decoction.If in pesticide, food Poison, often joins Semen phaseoli radiati or is decocted in water for oral dose with Radix Saposhnikoviae.For asthma and cough.Can be alone, also can compatibility other drug Application.As controlled the ERCHEN TANG of cough due to damp-phlegm；Control the Linggan Wuwei Jiangxin Tang of cold-phlegm cough with asthma；Control dry stool phlegm cough Sangxing decoction；Control pyretic toxicity and cause lung abscess cough and spit and smell as of rotten fish the Radix Platycodonis decoction of purulent sputum；Control the Gancao Ganjiang of cough and spit saliva foam Soup etc..Another cough due to pathogenic wind-heat, cough due to wind and cold, phlegm heat cough also Chang Peiwu application.For having a stomachache, suffer from abdominal pain and Gastrocnemius contraction urgency pain etc..For being in harmonious proportion the strong of some drugs.As seasoning CHENGQI TANG relaxes big by this product Yellow, the discharge function of Natrii Sulfas and gastrointestinal is stimulated.It addition, also commonly use this product in many prescriptions Coordinating the actions of various ingredients in a prescription.

Semen Oroxyli sore-throat relieving lung moistening；Dispersing the stagnated liver-QI for regulating the stomach；Expelling pus and promoting granulation.Cure mainly: pharyngalgia sore throat；Hoarseness； Cough；Stomachache due to hyperactive liver-QI attacking the stomach；Skin infection is burst for a long time and is not held back；Acute eczema.Effect is classified: antitussive；The lung moistening medicine；With Stomach medicine.Medical material Ji Yuan: for the mature seed of Bignoniaceae plant oroxylum indicum.Come from supplementary Amplifications of the Compendium of Materia Medica Seed, peel of stem contain baicaligenin, have antiinflammatory, antiallergic action, diuresis, function of gallbladder promoting, the work of cholesterol reducing With.

Exocarpium Citri Rubrum, Chinese medicine name.For rutaceae orange Citrus reticulata Blanco and variety thereof It is dried outside rind.Gather after time of the year when autumn changes into winter fruit maturation, cut lower outer peel with cutter, dry or dry in the shade. Acrid in the mouth, hardship, warm in nature.Return lung, spleen channel.Effect regulating the flow of QI to ease the stomach, drying dampness to eliminate phlegm.Cure mainly for coughing Abundant expectoration, food stagnation gets sick from drinking too much wine, and vomiting and nausea painful abdominal mass is vexed.Compendium of Material Medica: therapeutic method to keep the adverse QI flowing downwards expectorant." herbal classic is met former ": Fructus Citri tangerinae Red and expert main lung cold cough excessive phlegm, deficient side multiplex it, right chronic cough diarrhea due to stagnation of QI, the most non-preferably." medicineization justice ": Exocarpium Citri Rubrum, pungent eliminating stagnation of walking crosswise, bitter decline of keeping straight on, for promoting the circulation of QI key medicine.Lid is controlled expectorant and must be regulated the flow of vital energy, diarrhea due to disorder of QI expectorant Spontaneous recovery, therefore with entering lung spleen, all expectorant main are sick, and merit occupies on all expectorant medicines.Assistant Caulis Bambusae In Taenia, to treat heat-hiccup, helps green grass or young crops Skin is with intestinal stasis relieving gas, real in the flat stomach of same Rhizoma Atractylodis, Cortex Magnoliae Officinalis, the heresy that conjunction Bulbus Allii Fistulosi, Herba Ephedrae exterior cold are wet, rapid digestion of food gas, Alcoholic intoxication, anti-nausea, to open chest and diaphragm painful abdominal mass plug, Chen Zhixin can be pushed away, the power of the most pungent scattered bitter fall is also.

Poria sweet in the mouth, light, property is put down.GUIXIN, lung, spleen, kidney channel.Effect promoting diuresis to eliminate damp pathogen, spleen invigorating, Mind calming.Cure mainly for edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, loose stool has loose bowels, irritability, Palpitation with fear insomnia.Compendium of Material Medica: Poria abnormal smells from the patient is light and oozes, and its property is up, born fluid, loosing the interspaces of skin and muscles, Grow water source and decline, diuresis, therefore Zhang Jiegu calls its genus sun, floats and rises, says its property also；Dong Yuan calls it For the YIN aspect of YANG, fall and under, Yan Qigong is also.Amplification on Canon of Materia Medica: Poria, Poria cum Radix Pini, the merit of row water is many, Heart-spleen boosting can not fault also.

Fructus Trichosanthis refers to Fructus Trichosanthis, have antipyretic quench the thirst, diuresis, the effect such as relieving cough and expelling phlegm.Seed is containing fat flower fat oil； Fruit contains triterpene saponin, organic acid, resin, saccharide, pigment；Root contains protein, saponin, acids. " Amplification on Materia Medica addendum ": " Fructus Trichosanthis is real, and the thoracic obstruction controlled in " herbal " speech, moistens with sweet in the mouth, sweet energy tonifying the lung, Profit can sending down the abnormal ascending QI.Breast has expectorant person, is forced by fire with lung, loses the order fallen, and Jin get Gan delays helping of relaxing the bowels with lubricant drugs, then expectorant From fall, preferably it is for controlling the key medicine coughed also.In washing chest and diaphragm, dirt is greasy again, controls the god's medicine quenched one's thirst also." " guiding principle Mesh ": " Zhang Zhongjing is controlled pain in the chest due to obstruction of QI and is drawn the heart back of the body, and cough and spit is panted, and blocked-up chest completely pain, all real with Fructus Trichosanthis, be Take its sweet trembling with fear and do not violate gastric qi, the fire of the part of the body cavity above the diaphragm housing the heart and lungs can be dropped, make mental disorder decline also.Cheng Wuji does not knows that this anticipates, and is cloud Bitter cold is to purge heat, and it is former the most bitter that lid does not taste its taste, and draws wrong conclusions by false analogy you with literary composition.”

Radix Trichosanthis, Chinese medicine name." book on Chinese herbal medicine justice ": medicine what is called Radix Trichosanthis person wantonly, i.e. with root section of withering With it, there is the name of powder, real without powder.Radix Trichosanthis is the root of cucurbitaceous plant Chinese juniper beach wormwood, is a kind of Chinese medicine, For clearing away heat-fire class medicine, its concrete effect is clearing away heat-fire, promoting the production of body fluid to quench thirst, and evacuation of pus is subsided a swelling.Cure mainly: Control that calentura is thirsty, quench one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid flaccidity.For treatment diabetes, conventional It with drugs for nourishing yin with the use of, to reach the effect for the treatment of both the principal and secondary aspects of a disease.

Spica Prunellae is pungent, bitter, cold.Return liver, gallbladder meridian.Clearing away heat-fire, improving eyesight, mass dissipating and swelling eliminating. conjunctival congestion swells Bitterly, headache dizziness, mesh pearl nyctalgia.This product bitter cold master enters Liver Channel, and kind removing fire from the liver is with improving eyesight.With treating the liver fire Upper inflammation, conjunctival congestion and swelling pain, Folium Mori, Flos Chrysanthemi, Semen Cassiae etc. can be joined medicinal.Among this product liver heat removing and eyesight improving, slightly Hold concurrently nourishing the liver, join Radix Angelicae Sinensis, Fructus Lycii, can be used for deficiecny of liver-YIN, ophthalmalgia, to night more particularly；Also may be used Join Rhizoma Cyperi, Radix Glycyrrhizae use, as Spica Prunellae dissipates (" Zhang Shi doctor is logical ").Shennong's Herbal: " main cold Heat, scrofula, scrofula, head sore, broken disease.Dissipate wart stagnation of QI, swelling of the feet arthralgia chiefly caused by damp pathogen.Compendium of Material Medica: " summer Hay controls ophthalmalgia, with Saccharum Sinensis Roxb. water logging one ight, takes it and can solve interior-heat, and slow liver-fire is also.Lou Quan is apt to cloud, summer Hay is controlled mesh pearl and aches to night the most notably, the magical effect, or with bitter cold snack made with traditional Chinese medicines instead the most notably, the also magical effect.Lid mesh pearl Even mesh is originally, and liver is also, belongs to the warp of the moon of fainting.Night is very and some bitter and cold medicines is anti-the most notably, night with cold also cloudy thus also. The gas of the summer pure sun of withered official report, mends cloudy blood vessels of fainting, therefore controls this as refreshing, with Yang Zhiyin also.”

Borneolum Syntheticum acrid in the mouth, hardship, be slightly cold；GUIXIN, liver, lung meridian；Delicate fragrance a surname dissipate, and has refreshment of having one's ideas straightened out, clearly Heat dissipates poison, effect of improving acuity of vision and removing nebula, cures mainly calentura unconsciousness due to high fever, and apoplexy syncope due to accumulation of phlegm infantile convulsion, heat-damp in summer blinds clearly Key, sore throat is deaf, and aphtha tooth swells, carbuncle sore infantile malnutrition hemorrhoid, conjunctival congestion and swelling pain, pterygium.Logical all keys, dissipate strongly fragrant Fire, removing nebula improving eyesight, reducing swelling and alleviating pain, heat clearing away dissipates poison, dissipates fire removing toxic substances.Control mammary gland to lump, apoplexy locked mouth, Calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, mesh is also Nebula film, enterobiasis." not Lu ": " married woman has difficult labour, and takes Borneolum Syntheticum and grinds into powder a little, is taken after mixing with liquid newly to draw water.″ Tang Materia Medica: " main trusted subordinate's pathogen, rheumatism is gathered, deaf.Improving eyesight, goes conjunctival congestion skin nebula." " sea medicine Book on Chinese herbal medicine ": " external oculopathy eye in main, three worms, control five hemorrhoid, improving eyesight, relieving palpitation, secret essence.″

Caulis Perillae, another name: Folium Perillae stem, Caulis Perillae, Folium Perillae bar.Latin literary fame Perilla frutescens (L.) Britton. it is a kind of Chinese medicine title.This product is labiate Folium Perillae Perillafrutescens (L.) Britt. Dry stem.Autumn taps after fruit maturation, removes impurity, dries, or take advantage of fresh slices, dry.Purple SUXIN temperature row dissipates, and leaf is gently such as lung, energy dispersing wind-cold, lung qi dispersing cough-relieving；Stalk such as taste, be good at circulation of qi promoting with in, Regulate the flow of vital energy antiabortive.Therefore commonly used by cough due to wind and cold, stagnation of QI in spleen and stomach, additionally, solve again the poison of fish Eriocheir sinensis.Diaphoresis solution Table (Folium Perillae is preferable): for anemofrigid cold, cough with copious phlegm.Curing mainly anemofrigid cold, aversion to cold is lossless；Wind The criminal's of trembling with fear lung, cough with copious phlegm；Affection of exogenous wind-cold, interior double stagnation of QI person's use better.Promoting the circulation of QI to alleviate the stagnation in middle-JIAO (Caulis Perillae, Soviet Union Pocket is preferable): for stagnation of QI in spleen and stomach, vomiting uncomfortable in chest.This product is promoting the circulation of QI to alleviate the stagnation in middle-JIAO, and activating QI to stop vomiting good medicine has concurrently Regulate the flow of vital energy antiabortive merit.

Radix Bupleuri, Chinese medicine name.The medical herbs included for " Chinese Pharmacopoeia ", medicinal part is samphire bavin Hu or the dry root of Radix Bupeuri Scorzonerfolii..Spring, season in autumn two excavate, and remove stem and leaf and silt, are dried.Radix Bupleuri is Conventional diaphoretic medicine.Another name ground smoke, mountain dish, mushroom grass, faggot, nature and flavor hardship, be slightly cold, return liver, gallbladder meridian. There are reconciling superficies and interior, effect of soothing the liver yang invigorating.For cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, Sternal rib pain, proctoptosis, uterine prolapse, menoxenia.

Rhizoma Cyperi hardship pungent, micro-, micro-sweet, flat.Return liver, spleen, tri-jiao channel.Dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach, Menstruction regulating and pain relieving.Cure mainly for stagnation of QI due to depression of the liver, distending pain in the chest and hypochondrium, hernia pain, distending pain of the breast, stagnation of QI in spleen and stomach, Gastral cavity abdomen painful abdominal mass is vexed, distension pain, menoxenia, amenorrhea dysmenorrhea." Amplification on Materia Medica addendum ": Rhizoma Cyperi, Must soak with urine of baby boys, all vim and vigour medicines must cause edema caused by disorder of QI and hemopoietic with it, and the justice of this Yin grows while yang is generating is also.Zhu Zhen Prosperous: Rhizoma Cyperi, " herbal " does not say benefit, and the Fan family says in old man useful, and here meaning deposits, and is placed in row and has Mend reason.

The pungent one-tenth of Bombyx Batryticatus is flat.Enter liver, lung, stomach warp.Function cures mainly expelling wind to relieve convulsion, dissipating phlegm and resolving masses.Control Apoplectic aphasia, infantile convulsion, wind syndrome of head, acute throat trouble.Sore throat, scrofula tuberculosis.Wind skin ulcer urticaria, erysipelas, mastitis. " herbal classic ": main pediatric epilepsy scared night cry, goes three worms, goes out black, and man's the moon infections is sick." not Lu ": female Sub-metrorrhagia is red in vain, and puerperal is remaining bitterly, all skin ulcer cicatrixs of going out.

Fructus Momordicae, the fruit of the perennial liana of Cucurbitaceae.Fruits nutrition is worth the highest, containing enrich Vitamin C (in every 100 grams of fresh fruits containing 400 milligrams～500 milligrams) and glucoside, fructose, glucose, Protein, lipid etc..Fructus Momordicae sweet in the mouth is cool in nature, returns lung, large intestine channel, has nourishing the lung to arrest cough, promoting the production of body fluid to quench thirst Effect, be applicable to lung-heat or xeropulmonary cough, pertussis and summer-heat impairment of body fluid are thirsty etc., in addition with intestine moistening Effect of relieving constipation.

Herba Menthae is one of China's conventional Chinese medicine.It is pungent cool property sweating antipyretic medicine, controls influenza, head Pain, conjunctival congestion, fever of the body, throat, dental bed such as swell and ache the disease.External can training the mind dysmenorrhoea, skin pruritus, erythra With eczema etc..Usually with Herba Menthae for tea, clear away heart-fire improving eyesight.

The root of Radix Scutellariae is used as medicine, bitter in the mouth, cold in nature, has heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the merit such as antiabortive Effect.Cure mainly epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, The diseases such as conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.The clinical antibiotic property of Radix Scutellariae is better than Rhizoma Coptidis, and And do not develop immunity to drugs.

Specific embodiment 1

The preparation of oral pills of the present invention:

By Cortex Moutan 1100g, Exocarpium Citri Rubrum 1200g, Radix Ophiopogonis 1200g, Fructus Gardeniae 1200g, Caulis Perillae 1100g, in vain Chinese herbaceous peony 1200g, Radix Bupleuri 1200g, Rhizoma Cyperi 1100g, Radix Glycyrrhizae 1100g, Radix Platycodonis 1200g, Semen Oroxyli 1100g, Poria 1200g, Rhizoma Anemarrhenae 1200g, Fructus Trichosanthis 1100g, Folium Eriobotryae 1200g, Radix Trichosanthis 1100g, Spica Prunellae 1200g, Radix Scutellariae 1100g.Add soak with ethanol 2-3 hour accounting for its quality 7-10 times, heating extraction 2 times, 1-2 hour every time, united extraction liquid, remove supernatant after standing, then 100-120 mesh filters, then through cutting Stream molecular weight is the ultrafiltration post ultrafiltration of 5000-10000, when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C 1.25 filtrate.The medicinal residues of the crude drug crossed by above-mentioned ethanol extraction again add 10 times amount water, are heated to reflux carrying Taking 2 times, each 1～2 hour, merged by 2 extracting solution and stand, ultrafiltrate concentrating under reduced pressure relative density is The filtrate of 1.25 when 80 DEG C, mixes two kinds of extraction filtrates and inserts in economic benefits and social benefits vacuum concentrator, be concentrated into 90 DEG C time relative density be the concentrated solution of 1.05, set to 0～5 DEG C of deepfreezes 24 hours；Cold preservation liquid is added 0.3% Filter aid kieselguhr, filter, filtrate inserts in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 0.1g Crude drug amount, then adds Mel and is twisted into pill.

Specific embodiment 2

The present invention takes granule orally:

By Cortex Moutan 1200g, Exocarpium Citri Rubrum 1200g, Radix Ophiopogonis 1200g, Fructus Gardeniae 1200g, Caulis Perillae 1200g, in vain Chinese herbaceous peony 1200g, Radix Bupleuri 1200g, Rhizoma Cyperi 1200g, Radix Glycyrrhizae 1200g, Radix Platycodonis 1200g, Semen Oroxyli 1200g, Poria 1200g, Rhizoma Anemarrhenae 1200g, Fructus Trichosanthis 1200g, Folium Eriobotryae 1200g, Radix Trichosanthis 1200g, Spica Prunellae 1200g, Radix Scutellariae 1200g.Chopping is soaked to be placed in lid stainless steel cask, adds 70% ethanol, matter Amount, for coarse grained 0.8-1 times, stirs, moistening airtight placement more than 1 hour, makes fully to expand； After filter plate gauze bag parcel is paved bottom percolator, the drug sample after moistening expansion is mixed pine lane again Dissipate, then contain powder with rustless steel spoon, load percolator uniformly, fill 10-12 cm thick, use T-bar pressure Even, then press aforesaid operations, loading in layer, suitably pressurize, medicated powder loads and must not exceed percolator 2/3 eminence；Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts one Container, is then slowly added into 70% ethanol；Air between medicated powder powder to be discharged, and have ethanol stream Go out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and ooze Filtering, control percolation speed and be generally 1000g medical material outflow per minute 2～3ml, filtrate puts into liquid container, And pour ethanol during emptying into liquid container；Percolate is merged and stands, stand for standby use；By filter Filtrate is inserted in economic benefits and social benefits vacuum concentrator, and when being concentrated into 90 DEG C, relative density is the concentrated solution of 1.05, set to 0～ 5 DEG C of deepfreezes 24 hours；The filter aid kieselguhr adding 0.3% by cold preservation liquid, filters, and filtrate is inserted again In economic benefits and social benefits vacuum concentrator, it is concentrated into every 1ml crude drug amount Han 0.1g, adds dextrin or granulated into particles.

Specific embodiment 3

The preparation method of external spraying agent:

Radix Angelicae Dahuricae 1000g, Pseudobulbus Bletillae (Rhizoma Bletillae) 1000g, Herba Menthae 1000g, Borneolum Syntheticum 1000g and Rhizoma Et Radix Notopterygii 1000g are distilled Method is vaporized into crystallization, pulverizes stand-by, for component 1；Other raw materials Bombyx Batryticatus 1000g, Fructus Momordicae 1000g Folium Artemisiae Argyi 1000g, Radix Clematidis 1000g, by soak with ethanol, heated and boiled 3 times, each 1-2 hour, filter, Filtrate is standby；By in the filtrate suction concentrating under reduced pressure tank merging latter 3 times, being evaporated to relative density is 1.20, the extractum of temperature to 60 DEG C-70 DEG C；Become component 2, blending ingredients 1 and component 2, then with Citrullus vulgaris Frost 1000g, mediation substrate, load in aerosol apparatus.

Specific embodiment 4

The preparation method of the liniment of external is

Just Radix Angelicae Dahuricae 1200g, Pseudobulbus Bletillae (Rhizoma Bletillae) 1400g, Herba Menthae 1300g, Borneolum Syntheticum 1200g and Rhizoma Et Radix Notopterygii 1200g steam The method of evaporating is vaporized into crystallization, pulverizes stand-by, for component 1；Other raw materials Bombyx Batryticatus 1300g, Fructus Momordicae 1200g Folium Artemisiae Argyi 1400g, Radix Clematidis 1200g, soaked and be placed in lid stainless steel cask, adds 70% ethanol, Quality is coarse grained 0.8-1 times, stirs, moistening airtight placement more than 1 hour, makes fully to expand； After filter plate gauze bag parcel is paved bottom percolator, the drug sample after moistening expansion is mixed pine lane again Dissipate, then contain powder with rustless steel spoon, load percolator uniformly, fill 10-12 cm thick, use T-bar pressure Even, then press aforesaid operations, loading in layer, suitably pressurize, medicated powder loads and must not exceed percolator 2/3 eminence；Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts one Container, is then slowly added into 70% ethanol；Air between medicated powder powder to be discharged, and have ethanol stream Go out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and ooze Filtering, control percolation speed and be generally 1000g medical material outflow per minute 2～3ml, filtrate puts into liquid container, And pour ethanol during emptying into liquid container；Percolate is merged and stands, stand for standby use；By filter Filtrate is inserted in economic benefits and social benefits vacuum concentrator, and when being concentrated into 90 DEG C, relative density is the concentrated solution of 1.05, set to 0～ 5 DEG C of deepfreezes 24 hours；The filter aid kieselguhr adding 0.3% by cold preservation liquid, filters, and filtrate is inserted again In economic benefits and social benefits vacuum concentrator, it is concentrated into every 1ml crude drug amount Han 0.1g, for component 2.By component 1 and component 2 Merging, add watermelon crystal 1300g be in harmonious proportion substrate, sterilizing bottling cold preservation.

Toxicology test:

Test example 1: acute toxicity test of the present invention

One, test material:

Animal: Kunming mouse, body weight 21-24g, male and female half and half, Shandong University's biology laboratory breeding. Medicine: oral capsule of the present invention.

Two, method:

1, LD50 calculates: use improvement karber's method, mice is randomly divided into 5 groups, often group 10, Male and female half and half, dissolve suppository, are made into Cmax, are administered by the maximum allowable capacity of mice, given agent Amount is followed successively by 18 by crude drug amount, and 14.4,11.5,9.2,7.4 (g.kg-1), in animal fasting (can't help water) 18 After hour, it is administered (interval half an hour), each 0.Sml in one day at twice, treats animal dead situation.

2, maximum tolerated dose measures (MTD value): take mice 20, each 10 of male and female.By suppository Adding distilled water to dissolve, be made into maximum concentration, by the maximum tolerated dose of animal, filling hello device with injection can twitch It is as the criterion.After animal fasting (can't help water) 18 hours, it is administered at twice in one day (interval half an hour), often Secondary 0.5ml (every m1 0.36g Han crude drug), total dose is 18g crude drug/kg.d, quite clinical adult 50Kg 300 times of body weight consumption.Treat 7 days continuously after administration.

Three, result of the test:

In LD50 calculates when giving mice with maximum acceptable concentration and maximum allowable capacity (18g/Kg.d), have no dead mouse, i.e. do not measure LD50, seek maximum tolerated dose only, at 7 days Treating interim, its appetite of animal, activity, hair color, the mental status etc. are all normal, grow normal, have no There is death.I.e. select the 300 times of doses being equivalent to clinical dosage, and have no adverse reaction, show urgency Property toxicity is minimum, MTD ＞ 18g/Kg.d.

Test example 2: acute skin irritation test of the present invention is reported

1, experiment purpose: detect the spray of the present invention stimulation/corrosiveness to laboratory animal skin with strong Degree

2, material and method:

2.1. tested material: title: spray of the present invention (embodiment 3 method prepares)

2.2. laboratory animal: one grade of big ear white race rabbit, 10, female, body weight 2.1-2.3kg；By green grass or young crops Island University Medical College biology department Experimental Animal Center provides；

2.3. test method:

Select the healthy rabbits 10 that skin is intact, in testing first 24 hours by its spinal column both sides, back quilt Hair is cut, and removes the left and right each about 4cm × 4cm of gross area.Take tested material 0.2ml during test and be applied to 2.5cm On two layers of gauze of × 2.5cm, being applied to skin of unhairing surface, side, oilpaper covers, immobilization with adhesive tape. Opposite side skin is as blank.After closing 4 hours, dismantle, and go residual with warm water cleaning Staying tested material, position dermoreaction is smeared in the treatments in 1,24 and 48 hours after removing tested material, and Scoring.

3, experimental result: any erythema does not occurs in laboratory animal skin, red and swollen, inflammation phenomenon.

4, brief summary: judge according to skin wound repair standards of grading in " disinfection technology standard " (1999), Ointment of the present invention belongs to nonirritant to animal skin stimulus intensity.

Pharmacological experiment

Chronic pharyngitis is common clinical, frequently-occurring disease, how by acute pharyngitis recurrent exerbation, adjacent tissue Chronic inflammatory disease, or lured by pessimal stimulations such as cigarette, wine, climatic factor, and digestive disorders for a long time Send out；Clinical with pharyngalgia, itching throat, hawk cough, and foreign body in pharynx sense is main performance.This disease often makes patient Feelings will is not relaxed, state of an illness performance multiterminal, and recurrent exerbation, touching difficulty more, is treated the most thorny.2013 8 In March ,-2014 moon, the author uses soothing the liver sore-throat relieving soup to treat phlegm stagnation pattern of fever chronic pharyngitis 135 example, sums up Report as follows.

1 physical data

Select this Out-patient Department patients with chronic pharyngitis 135 example, male 55 examples, female 80 example；Age 10～20 years old 8 Example, 21～30 years old 16 example, 31～45 years old 92 example, 46～60 years old 19 example；The course of disease is the shortest 6 months, Long 10 years.

2 diagnostic criterias

According to<Chinese medical disease Standardization of diagnosis and curative effect>.Phlegm stagnation heat clinic syndrome: parched throat hypodynia, pharyngeal Foreign body sensation is obvious, and that tells does not goes out, and can not swallow, when feelings will is not smooth more so, being irritable and getting angry easily, the breast side of body is vexed swollen, Pharynx rear wall follicle hypertrophy, defecates uncomfortable, red tongue or light red, yellow and greasy fur, wiry and frequent pulse, and clinical manifestation is pharynx Portion is dried or itches bitterly, foreign body sensation, and twinge is uncomfortable, checks pharyngeal mucosa chronic congestion, swelling, plumpness, Retropharyneal folliculosis.Method for the treatment of: Shugan Qingre, reduce phlegm sore-throat relieving.

3 Therapeutic Method

Give the present invention soothing the liver sore-throat relieving soup, medicine form: Cortex Moutan 15g, Exocarpium Citri Rubrum 12g, Radix Ophiopogonis 14g, Cape jasmine Sub-13g, Caulis Perillae 14g, Radix Paeoniae Alba 13g, Radix Bupleuri 14g, Rhizoma Cyperi 14g, Radix Glycyrrhizae 11g, Radix Platycodonis 11g, Semen Oroxyli 11g, Poria 12g, Rhizoma Anemarrhenae 13g, Fructus Trichosanthis 12g, Folium Eriobotryae 13g, Radix Trichosanthis 11g, the summer is withered Grass 11g, Radix Scutellariae 11g.It is decocted in water for oral dose, 1d 1 dose, divides 2 decoction being taken warmly after meal sooner or later.

External: watermelon crystal 12g, Radix Angelicae Dahuricae 13g, Pseudobulbus Bletillae (Rhizoma Bletillae) 14g, Herba Menthae 12g, Borneolum Syntheticum 15g, Bombyx Batryticatus 12g, Fructus Momordicae 13g, Rhizoma Et Radix Notopterygii 12g, Folium Artemisiae Argyi 12g, Radix Clematidis 12g.Make spray, make every day With 3 times.Within 1 week, being 1 course for the treatment of, general 2～5 courses for the treatment of take effect.

4 curative effect determinate standards

Work out with reference to " new Chinese medicine guideline of clinical investigations ".Clinical cure: subjective symptoms and pharynx Portion's disease damage is wholly absent, without recurrence in half a year.Effective: subjective symptoms and pharyngeal disease damage partial disappearance, 1 Without recurrence in individual month.Invalid: subjective symptoms and pharyngeal disease damage, without changing or increasing the weight of, recur in 1 month.

5 results

Clinical cure 91 example, effective 32 examples, invalid 12 examples, effectively account for 91.11%.

Chronic pharyngitis is the most multiple, and symptom stubbornness is difficult to cure.Pharyngeal sense of discomfort easily makes patient heart not Good, suspicious, the state of an illness, the interaction of both moods, make state of an illness stubbornness complicated, be also one of refractory reason. Primary disease belongs to Chinese medicine " sore throat " category.<Huang di's Canon of Medicine>is loaded with " spleen is too late, then nine orifices is different ". Holy Benevolent Prescriptions is said: " pharynx person swallows also, and sky can swallow thing, the again choke of meaning, main tonneau water paddy, gastric qi Path." say again: " also, speech is wherein hollow, can lead in QI and blood, breathe into lung for throat person's inanition The circulation of gas." " Plain Questions passages through which vital energy circulates another matter " say: " spleen-QI transporting the essence to the whole body, is above attributed to lung, crystal four cloth, The Five Classics is parallel." say again: " kidney meridian of Foot-SHAO YIN, is main kidney disease of viscera connecting with this channel person, and the hot dry tongue of mouth, on pharyngeal swelling Gas, dry sensation in the pharynx and pain." as can be seen here, throat and lung, spleen, kidney relation are the closest.Passages through which vital energy circulates " the cloth of liver Side of body rib, after following throat, above enters neck forehead " " Plain Questions QI and blood shape will " is pointed out: " excessive physical exertion and mental depression, Diease occurrence is in pharynx." liver controlling conveyance and dispersion, happiness bar reaches and depressed.The liver failing to maintain the normal flow of QI, depression of liver-QI, perverse and unreasonable manner criminal's spleen, Insufficiency of the spleen dry phlegm-syndrome, mental disorder is handed over and is hindered in throat generation sore throat；The stagnation of QI with the passing of time, then must blood stasis, " prolonged illness must the stasis of blood ", Stagnation of blood stasis is in throat, and sore throat is the most touching.Visible, feelings will Nervous and Mental Factors causes the liver failing to maintain the normal flow of QI to be primary disease Morbidity because of, gas, blood, expectorant, the stasis of blood are the major pathologic features of primary disease, and lung, spleen, renal function are not normal It is only primary disease pathogenesis basis.

Radix Curcumae, Caulis Perillae, Exocarpium Citri Rubrum dispersing the stagnated live-QI to relieve the stagnation of QI in soothing the liver sore-throat relieving soup side, relieving distension by promoting circulation of QI, drying dampness to eliminate phlegm, Regulating qi-flowing for strengthening spleen, with the trouble of eliminating phlegm-retention condensation；Folium Eriobotryae, Radix Scutellariae clearing away lung-heat and moistening for dryness, preventing phlegm from forming and stopping coughing, fall of purging heat Fire, with the lung-fire of the clear part of the body cavity above the diaphragm housing the heart and lungs；Fructus Trichosanthis, Radix Trichosanthis kidney tonifying yin nourishing, alleviating distention in middle-JIAO regulates the flow of vital energy, and the raw gold of lung moistening, with gold Aqueous phase is raw, is linked up up and down by lung kidney；Cortex Moutan, Bulbus Fritillariae Thunbergii blood circulation promoting and blood stasis dispelling, relieving restlessness calms the nerves, heat clearing away eliminating stagnation, With stasis in the pharynx that disappears；Spica Prunellae, Fructus Gardeniae, the Bombyx Batryticatus pharyngeal follicle hypertrophy of dissipation；Radix Platycodonis, Semen Oroxyli, thin Lotus expelling phlegm for arresting cough, lung qi dispersing sore-throat relieving, with the up throat of priming.Entirely can soothing the liver circulation of qi promoting, eliminating stasis and resolving masses, reason Gas spleen invigorating, kidney tonifying lung moistening, so, then treating both the principal and secondary aspects of a disease, thus clinical with it, control repeatly and imitate repeatly.

Claims

1. the preparation method treating phlegm stagnation pattern of fever chronic pharyngitis Chinese medicine composition, it is characterised in that Including endo-medicine and external used medicine；Described endo-medicine is tablet, and its preparation method comprises the following steps:

A. the extraction of raw material medicinal alcohol is taken, as component 1；

Treat the preparation side of phlegm stagnation pattern of fever chronic pharyngitis Chinese medicine composition the most according to claim 1 All crude drug are shredded by method, it is characterised in that in described step a, are soaked and have been placed in lid not In rust steel drum, adding 70% ethanol, quality is coarse grained 0.8-1 times, stirs, and moistens airtight putting Put more than 1 hour, make fully to expand；Filter plate gauze bag bottom percolator is wrapped up after paving again by wet Drug sample after profit expansion is mixed pine and is done to dissipate, and then with rustless steel spoon Sheng powder, loads percolator uniformly, Dress 10-12 cm thick, even by T-bar pressure, then press aforesaid operations, and loading in layer, suitably pressurize, Medicated powder loads 2/3 eminence that must not exceed percolator；Medicated powder face upper cover rustless steel orifice plate fastens, and opens percolation Cylinder baiting valve below, and put a container, then it is slowly added into 70% ethanol；Medicated powder powder to be discharged Between air, and have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 little Time, then open baiting valve and carry out percolation, control percolation speed be generally 1000g medical material outflow per minute 2～ 3ml, filtrate is put into liquid container, and is poured ethanol during emptying into liquid container；Percolate is merged Standing, stand for standby use, as component 1.

Treat the preparation side of phlegm stagnation pattern of fever chronic pharyngitis Chinese medicine composition the most according to claim 1 Method, it is characterised in that in described step b, puts into weight 10 times amount by above-mentioned stripped raw material residue In water, soak 1-2 hour, heating extraction 2 times, each 1-2 hour, remove supernatant, united extraction liquid, 100-120 mesh filters, then the ultrafiltration post ultrafiltration that molecular weight is 5000-10000 through damming, and ultrafiltrate decompression is dense The filtrate of 1.05 when contracting relative density is 80 DEG C, as component 2.

Treat the preparation side of phlegm stagnation pattern of fever chronic pharyngitis Chinese medicine composition the most according to claim 1 Method, it is characterised in that in described step c, by 2-in-1 also to component 1 and component, puts into economic benefits and social benefits vacuum concentrator Middle mixing, first concentrating the filtrate to relative density when 80 DEG C is the concentrated solution of 1.32, sets to 0～5 DEG C of low temperature colds Hide 24 hours；The filter aid kieselguhr adding 0.3% by cold preservation liquid, filters, and it is dense that filtrate inserts economic benefits and social benefits vacuum again In contracting device, it is concentrated into every 1ml extractum Han 0.1g, then adds dextrin or starch tabletting, pack.

5. the preparation method treating phlegm stagnation pattern of fever chronic pharyngitis Chinese medicine composition, it is characterised in that Including endo-medicine and external used medicine；Described external used medicine is spray, and its preparation method is following steps:

C., watermelon crystal being put into solubilizer after component 1 component 2 mixes be in harmonious proportion, sterilization loads aerosol apparatus, must be cold Hide.

Treat the external used medicine of phlegm stagnation pattern of fever chronic pharyngitis Chinese medicine composition the most according to claim 1 Preparation method, it is characterised in that in described step a, first by the crude drug Radix Angelicae Dahuricae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Menthae, Borneolum Syntheticum and Rhizoma Et Radix Notopterygii steam method distill, and obtain crystal, then pulverize, cross 100-120 mesh sieve, as Component 1 is standby.

Treat the external used medicine of phlegm stagnation pattern of fever chronic pharyngitis Chinese medicine composition the most according to claim 1 Preparation method, it is characterised in that in described step b, remaining crude drug except watermelon crystal is put into 10 In times amount ethanol, soak 1-2 hour, heating extraction 2 times, each 1-2 hour, go supernatant, merging to carry Taking liquid, 100-120 mesh filters, then the ultrafiltration post ultrafiltration that molecular weight is 5000-10000 through damming, ultrafiltrate The filtrate of 1.05 when concentrating under reduced pressure relative density is 80 DEG C, as component 2；Watermelon crystal is put into component 1 In component 2, stir, solubilizer, load in aerosol apparatus, cold preservation.

8. the Chinese medicine composition treating phlegm stagnation pattern of fever chronic pharyngitis, it is characterised in that in described Drug composition includes endo-medicine and external used medicine；

Described endo-medicine includes the crude drug of following parts by weight: Cortex Moutan 10～20 parts, Exocarpium Citri Rubrum 10～20 Part, Radix Ophiopogonis 10～20 parts, Fructus Gardeniae 10～20 parts, Caulis Perillae 10～20 parts, the Radix Paeoniae Alba 10～20 parts, Radix Bupleuri 10～20 parts, Rhizoma Cyperi 10～20 parts, Radix Glycyrrhizae 10～20 parts, Radix Platycodonis 10～20 parts, Semen Oroxyli 10～20 parts, Poria 10～20 parts, the Rhizoma Anemarrhenae 10～20 parts, Fructus Trichosanthis 10～20 parts, Folium Eriobotryae 10～20 parts, Radix Trichosanthis 10～ 20 parts, Spica Prunellae 10～20 parts, Radix Scutellariae 10～20 parts；

Described external used medicine includes the crude drug of following parts by weight: watermelon crystal 10～20 parts, the Radix Angelicae Dahuricae 10～ 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10～20 parts, Herba Menthae 10～20 parts, Borneolum Syntheticum 10～20 parts, Bombyx Batryticatus 10～20 parts, sieve Chinese fruit 10～20 parts, Rhizoma Et Radix Notopterygii 10～20 parts, Folium Artemisiae Argyi 10～20 parts, Radix Clematidis 10～20 parts.

Treat the Chinese medicine composition of phlegm stagnation pattern of fever chronic pharyngitis, its feature the most according to claim 8 It is,

Described endo-medicine includes the crude drug of following parts by weight: Cortex Moutan 10～15 parts, Exocarpium Citri Rubrum 10～15 Part, Radix Ophiopogonis 10～15 parts, Fructus Gardeniae 10～15 parts, Caulis Perillae 10～15 parts, the Radix Paeoniae Alba 10～15 parts, Radix Bupleuri 10～15 parts, Rhizoma Cyperi 10～15 parts, Radix Glycyrrhizae 10～15 parts, Radix Platycodonis 10～15 parts, Semen Oroxyli 10～20 parts, Poria 10～20 parts, the Rhizoma Anemarrhenae 10～20 parts, Fructus Trichosanthis 10～20 parts, Folium Eriobotryae 10～20 parts, Radix Trichosanthis 10～ 20 parts, Spica Prunellae 10～20 parts, Radix Scutellariae 10～20 parts；

Described external used medicine includes the crude drug of following parts by weight: watermelon crystal 10～15 parts, the Radix Angelicae Dahuricae 10～ 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10～15 parts, Herba Menthae 10～15 parts, Borneolum Syntheticum 10～15 parts, Bombyx Batryticatus 10～20 parts, sieve Chinese fruit 10～20 parts, Rhizoma Et Radix Notopterygii 10～20 parts, Folium Artemisiae Argyi 10～20 parts, Radix Clematidis 10～20 parts.

The most according to claim 8, treat the Chinese medicine composition of phlegm stagnation pattern of fever chronic pharyngitis, it is special Levy and be,

Described endo-medicine includes the crude drug of following parts by weight: Cortex Moutan 10～20 parts, Periostracum Cicadae 10～20 Part, Radix Ophiopogonis 10～20 parts, Fructus Gardeniae 10～20 parts, Caulis Perillae 10～20 parts, the Radix Paeoniae Alba 10～20 parts, Radix Bupleuri 10～20 parts, Rhizoma Cyperi 10～20 parts, Radix Glycyrrhizae 10～20 parts, Radix Platycodonis 10～20 parts, Semen Oroxyli 10～15 parts, Poria 10～15 parts, the Rhizoma Anemarrhenae 10～15 parts, Fructus Trichosanthis 10～15 parts, Folium Eriobotryae 10～15 parts, Radix Trichosanthis 10～ 15 parts, Spica Prunellae 10～15 parts, Radix Scutellariae 10～15 parts；

Described external used medicine includes the crude drug of following parts by weight: watermelon crystal 10～20 parts, the Radix Angelicae Dahuricae 10～ 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10～20 parts, Herba Menthae 10～20 parts, Borneolum Syntheticum 10～20 parts, Bombyx Batryticatus 10～15 parts, sieve Chinese fruit 10～15 parts, Rhizoma Et Radix Notopterygii 10～15 parts, Folium Artemisiae Argyi 10～15 parts, Radix Clematidis 10～15 parts.