CN105918821A - Compound enzyme liquid having effects of lowering high blood lipids, high blood pressure and high blood sugar, and improving immunity, and preparation method thereof - Google Patents
Compound enzyme liquid having effects of lowering high blood lipids, high blood pressure and high blood sugar, and improving immunity, and preparation method thereof Download PDFInfo
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- CN105918821A CN105918821A CN201610246864.0A CN201610246864A CN105918821A CN 105918821 A CN105918821 A CN 105918821A CN 201610246864 A CN201610246864 A CN 201610246864A CN 105918821 A CN105918821 A CN 105918821A
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- ZSJLQEPLLKMAKR-GKHCUFPYSA-N streptozocin Chemical compound O=NN(C)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O ZSJLQEPLLKMAKR-GKHCUFPYSA-N 0.000 description 1
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- XPFJYKARVSSRHE-UHFFFAOYSA-K trisodium;2-hydroxypropane-1,2,3-tricarboxylate;2-hydroxypropane-1,2,3-tricarboxylic acid Chemical compound [Na+].[Na+].[Na+].OC(=O)CC(O)(C(O)=O)CC(O)=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O XPFJYKARVSSRHE-UHFFFAOYSA-K 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
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- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- SGEWCQFRYRRZDC-VPRICQMDSA-N vitexin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1C1=C(O)C=C(O)C2=C1OC(C=1C=CC(O)=CC=1)=CC2=O SGEWCQFRYRRZDC-VPRICQMDSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/113—Acidophilus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/169—Plantarum
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to the technical field of functional foods and especially relates to compound enzyme liquid having effects of lowering high blood lipids, high blood pressure and high blood sugar, and improving immunity, and a preparation method thereof. The compound enzyme liquid is prepared by selecting traditional Chinese medicines, fruits, vegetables, beans, grains, and microbes as fermentation raw materials, and conducting lactic acid fermentation, alcohol fermentation and acetic acid fermentation, and the obtained enzyme is a natural phytonutrient which is full in nutrients and high in dietary fiber, can lower high blood lipids, high blood pressure and high blood sugar, and improve immunity, and is suitable for the public needs.
Description
Technical field
The present invention relates to technical field of functional food, particularly relate to have and drop three-hypers and improve the comprehensive of immunity function
Enzyme liquid and preparation method thereof.
Background technology
" three-hypers disease " is the general name of hyperlipidemia, hypertension, hyperglycemia, and they threes are probably individualism, it is possible to
Can be interrelated.Hyperlipidemia can make blood vessel embolism, vessel wall elasticity weaken, sclerosis of blood vessels, blood pressure raise；High blood
Sugar can cause diabetes, and a lot of diabetes patients are with hyperlipidemia, and think that hyperlipidemia is the complication of diabetes,
When diabetes cause hyperlipidemia to be mainly insufficient insulin, internal lipase activity will reduce, and the most also accompanies protein
With water, fat, dielectric disorder, if on the other hand diabetes patient moves few, that but eats is too much, will make
The synthesis of internal lipid increases, and therefore blood fat easily increases；Diabetes patient raises, easily due to kidney injury and blood fat
Cause elevation of the blood pressure, it can be seen that, triadic relation is close, any one of these three illness occurs, and the later stage all holds
It is easily formed " three-hypers disease ".
Although at present we believe that " three-hypers disease " is owing to living standard is good, it is " rich and honour that endotrophic surplus causes
Sick ", " three-hypers disease " is owing to internal metabolism there is a problem in fact, belongs to metabolic syndrome.Height due to present people
Fat diet, often stay up late, pressure is big, all brings many burdens to body metabolism, it is therefore desirable to be continuously replenished complete
The nutrient substance of face equilibrium is to maintain the activity of internal enzyme.
Summary of the invention
The main object of the present invention is i.e. for modern's internal metabolism produced problem, it is provided that one has fall three
Height the comprehensive enzyme liquid improving immunity function and preparation method thereof.Active Chinese drug component extract is compound to fruit and vegerable ferment
In element, shorten the fermentation period of Chinese medicine.Selecting Chinese medicine, water fruits and vegetables, beans, corn, mushroom is fermentation
Raw material, through lactate fermentation, alcohol fermentation and acetic fermentation, the ferment of gained is a kind of fully nutrient, high meals
Fiber, the natural plant nutrient of three-hypers and enhancing immunity can be dropped, be suitable for public demand.
The present invention adopts the following technical scheme that:
There is fall three-hypers and improve the comprehensive enzyme liquid of immunity function, mainly being prepared by the raw material of following parts by weight
Form:
Chinese medicine: Semen Cassiae 3～5 parts, Fructus Crataegi 3～5 parts, Pachyrhizua angulatus 4～6 parts, Ganoderma 2～3 parts, Herb Gynostemmae Pentaphylli 2～
3 parts, Lepidinm meyenii Walp 2～3 parts；
Corn: Semen sojae atricolor 4～6 parts, Semen sojae atricolor 3～5 parts, Semen Sesami Nigrum 3～5 parts, Radix Et Rhizoma Fagopyri Tatarici 7～9 parts, Herba bromi japonici 2～
3 parts；
Vegetable: Bulbus Allii 2～3 parts, Bulbus Allii Cepae 2～3 parts, Rhizoma Zingiberis Recens 1～2 parts, Thallus Laminariae (Thallus Eckloniae) 1～2 parts, Thallus Porphyrae 1～2
Part, Fructus Solani melongenae 1～2 parts, cauliflower 1～2 parts, Fructus Momordicae charantiae 1～2 parts, Herba Apii graveolentis 2～3 parts, Semen Phaseoli radiati Germinatus 1～2 parts,
Fructus Cucumidis sativi 1～2 parts, Semen Maydis 1～2 parts, Rhizoma Dioscoreae 1～2 parts, Radix Dauci Sativae 1～2 parts, white turnip 1～2 parts, south
Melon 1～2 parts, Fructus Lycopersici esculenti 1～2 parts, Tremella 1～2 parts, Flammulina velutiper (Fr.) Sing 1～2 parts, Volvariella volvacea (Bull.Ex Franch.) Singer． 1～2 parts；
Fruit: Fructus Mali pumilae 4～6 parts, Citrullus vulgaris 3～5 parts, Fructus actinidiae chinensis 3～5 parts, pears 4～5 parts, Hylocereus undatus 5～7
Part.
The preparation method of above-mentioned comprehensive enzyme liquid, comprises the steps:
A, by after all kinds of vegetables and fruit respective pretreatment pull an oar, then each slurry is mixed, add mass fraction be
0.05～the cellulase of 0.1% and 0.05～0.1% pectase carry out enzymolysis, being added followed by mass fraction is
0.02～the protease of 0.05% and 0.1% α-amylase carry out enzymolysis, in the fruit and vegerable enzymolysis solution obtained inoculate ferment
Female bacterium and lactic acid bacteria, stirring and evenly mixing, seal, uniform temperature bottom fermentation 2 months, obtain fruit-vegerable ferment；
B, by corn clean after be mixed in stainless-steel pan, steaming and decocting of opening fire after soaking 5h, after boiling maintain 2～
3h, allows all corn steam moisture in the soft heart and pot and just boils dry, aseptically spread out by corn and be cooled to
Room temperature, is subsequently adding the sterilized water of five times of raw material volume, inoculation yeast bacterium, stirring and evenly mixing, seals, uniform temperature
Bottom fermentation 2 months, obtains corn ferment；
C, extraction active Chinese drug component material；
D, mixing fruit-vegerable ferment, corn ferment and active Chinese drug component material, stir, and obtains mixing enzyme liquid,
Add acetic acid bacteria, seal after stirring, uniform temperature bottom fermentation 1～2 months, then filter, filtrate
Adding mass fraction after weighing is 0.2% stevioside, seals after mixing, and room temperature is placed 1 month；Then carry out
Membrane filtration is degerming, sterile filling.
Described step c is extracted active Chinese drug component material and is comprised the steps:
C1: Ganoderma, Semen Cassiae, Fructus Crataegi, Pachyrhizua angulatus, Herb Gynostemmae Pentaphylli and Lepidinm meyenii Walp cross 40 mesh sieves after pulverizing, and add 70%
Edible ethanol until do not had raw material 5～10cm, soak 24h under room temperature and extract, period shakes one every 3h
Secondary, residue is recovered by filtration, gained filtrate is first time extracting solution；
Residue obtained middle addition sterilized water in c2:c1, adds mass fraction and is respectively the cellulase, really of 0.1%
Glue enzyme and protease carry out enzymolysis breaking cellular wall, and 40 DEG C are soaked 24h, and period shakes once every 3h, and residue is recovered by filtration,
Gained filtrate is second time extracting solution；
C3: repeat c2, obtains third time extracting solution；
C4: merge three extracting solution, 45 DEG C of concentrating under reduced pressure are evaporated and obtain active Chinese drug component extract, and extract is with a small amount of
The edible ethanol of 50% is dissolved.
The hydrolysis pH scope of described step a cellulase and pectase is 3.0～4.5, temperature range be 40～
50 DEG C, enzymolysis 5～10 hours；The hydrolysis pH scope of protease and α-amylase is 6.0～7.5, temperature range
It is 35～45 DEG C, carries out enzymolysis 3～7 hours.
Fermentation temperature in described step a, b, d is 28～32 DEG C.
Yeast in described step a, b is Candida utilis and beer yeast, lactic acid bacteria be bacillus acidophilus and
Lactobacillus plantarum, vaccination ways be every kind of strain be 1 × 10 by the inoculum concentration inoculating active bacterium number of 100g/t9Cfu/g's
Active microbe powder.
Acetic acid bacteria in described step d is Acetobacter pasteurianus, and vaccination ways is that every kind of strain is by the inoculation of 100g/t
Amount inoculating active bacterium number is 1 × 109The active microbe powder of cfu/g.
The aperture of the filter membrane in described step d is 0.1～0.2 μm.
Vegetable and fruit pretreatment in described step a include: removed by Fructus actinidiae chinensis surface pubescence, various fruit vegetables
Dish is cleaned in clear water, then carries out overflow-type submergence sterilization in Ozone Water, dries, after sterilization under aseptic condition
Bulbus Allii, Hylocereus undatus peeling, Fructus Momordicae charantiae removes seed.
In the present invention:
Ganoderma is the sporophore of On Polyporaceae Ganoderma, and sweet-bitter flavor, property are flat, can tranquilizing by nourishing the heart, quiet lung QI invigorating,
Regulating the flow of vital energy is become silted up, liver nourishing spleen invigorating.Through a large amount of clinical researches, Ganoderma is to neurasthenia, hyperlipemia, the coronary heart disease heart
Angor, arrhythmia, Keshan disease, plateau discomfort disease, hepatitis, hemorrhagic fever, dyspepsia, tracheitis, tumor
Curative effect etc. the degree of having nothing in common with each other.
Semen Cassiae is leguminous plant Semen Cassiae or the dry mature seed of little Semen Cassiae, have the merit of improving eyesight with it and name it.Its
Bitter in the mouth, sweet, salty, cold nature, loosening bowel to relieve constipation, blood fat reducing improving eyesight, constipation and hyperlipidemia, hypertension can be treated.
Fructus Crataegi is Rosaceae Crataegus Fructus Crataegi, drying after can be used as medicine, there is blood fat reducing, blood pressure, heart tonifying, anti-
Arrhythmias etc. act on, and are also the good medicine of spleen benefiting and stimulating the appetite, relieving dyspepsia, phlegm reduction of blood circulation promoting simultaneously, full to chest and diaphragm spleen,
The diseases such as hernia, blood stasis, amenorrhea have good curative effect.Flavone compound vitexin in Fructus Crataegi, is a kind of anticancer
Acting on stronger medicine, its extract all has certain work to the internal growth of cancer cells of suppression, propagation and infiltration metastasis
With.
Pachyrhizua angulatus is legume pueraria lobata or the dry root of Radix Puerariae rattan, and it is cool in nature, sweet in the mouth, pungent, and Compendium of Material Medica is remembered
Carry, Amylum Puerariae Radicis have relieve the effect of alcohol, effect of resolving heat and reducing pathogenic fire, nourishing YIN and invigorating YANG, promoting the production of body fluid to quench thirst, stimulating appetite, to treatment and
Prevention chest and diaphragm dysphoria with smothery sensation, middle wind headache, hypertension, coronary heart diseases and angina pectoris, blood fat reducing, diabetes, cerebral thrombosis,
Anticancer, the cancerous protuberance that disappears, lose weight fat, defying age, gastroenteropathy etc. all have special efficacy., detect through modern science meanwhile,
This product, containing trace element and several amino acids such as the zinc of needed by human, ferrum, calcium, vitamin B1, B2, is nutrition
It is worth the highest wholefood, women cosmetology and health etc. is had special efficacy simultaneously.
Herb Gynostemmae Pentaphylli is also known as paradise grass, Gospel grass, Chao Rencan, Herb Gynostemmae Pentaphylli, Herba Gynostemmatis, Herba Gynostemmatis, Pentapanax
With gynostemma pentaphyllum makino etc., it is Cucurbitaceae, Gynostemma herbaceous stem Climbing Plant.Arrange in pairs or groups to boil water with Herb Gynostemmae Pentaphylli and Ganoderma or make tea
Drink, the diseases such as hypertension, hyperlipidemia, hyperglycemia, fatty liver can be treated.Herb Gynostemmae Pentaphylli makes tea to be had well human body
Benefit, Herb Gynostemmae Pentaphylli tea have drawn from leaf of Herb Gynostemmae Pentaphylli armpit position tender shoots and dragon must, there is nutrient substance band contained by growing point
Come health care, long-term drink, without any side effects, can blood fat reducing, adjust blood pressure preventing and treating thrombosis, prevent and treat the heart
Vascular disorder, regulates blood glucose, promotees sleep, slow aging, anti-cancer, improves immunity, regulate human physiological functions.
Simultaneously Herb Gynostemmae Pentaphylli can protect adrenal gland and thymus and endocrine organ with the age growth and will not atrophy, maintain in point
Secrete the function of system.
Lepidinm meyenii Walp is mainly produced in South America Andes normal pulse Chinese yunnan Lijing, is a kind of crucifer.Leaf
Son is oval, rhizome likeness in form turnip radish, and edible is a kind of natural food, and nutrition is enriched.Lepidinm meyenii Walp contains
The protein (protein content of the Lepidinm meyenii Walp kind of Hu Ning lakeside is more than 14%) of more than 10%, the carbon aquation of 59%
Compound；The cellulose of 8.5%, include abundant zinc, calcium, ferrum, titanium, rubidium, potassium, sodium, copper, manganese, magnesium, strontium,
The mineral such as phosphorus, iodine, and containing vitamin C, B1, B2, B6, A, E, B12, B5, fat content is not
High but mostly wherein be unsaturated fatty acid, the content of linoleic acid plus linolenic acid reaches more than 53%, natural activity composition bag
Include alkaloid, glucosinolate and catabolite benzyl isothiocyanate, sterol, polyphenols etc..1999,
American scientist is found that in Maca containing the new vegetable active composition of two classes, macamides (macamides) and
Maca dilute (macaenes), and determine that both materials have remarkable effect to balanced human's hormone secretion, so
Maca is otherwise known as natural hormone electromotor.Lepidinm meyenii Walp have resisting fatigue, regain one's vigor, quickly regain one's strength of body,
Endocrine regulation, strengthen immunologic function, improve the effects such as anemia.Lepidinm meyenii Walp can be by balance thyroxine, insulin
In regulation blood fat, blood pressure, blood glucose, it is also possible to the activity of suppression Angiotensin-Converting I (can raising blood pressure),
Sterol and the essential fatty acid such as ω-6 (linoleic acid) and ω-3 (linolenic acid) in Lepidinm meyenii Walp can promote blood lipid metabolism,
And then reduce blood pressure and blood fat, improve the sequela problem that cerebral thrombosis causes.
The present invention selects six kinds of Chinese medicines with fall three-hypers effect, and wherein Fructus Crataegi, Semen Cassiae and Pachyrhizua angulatus are integration of edible and medicinal herbs
Article, and Ganoderma, Herb Gynostemmae Pentaphylli, Lepidinm meyenii Walp are the article that can be used for health product, and these Chinese medicines are all proved to can be long-term
Edible, nontoxic.Additionally in the present invention, remaining fruit and vegerable corn is respectively provided with fall three-hypers effect in various degree, several
Veterinary antibiotics, corn, mushroom comprehensively ferment, and nutrition more equalizes comprehensively, are the preferable recipes of three-hypers crowd.
Several Chinese medicines are first extracted by the present invention with edible ethanol, then with water extraction active Chinese drug component thing after enzymolysis breaking cellular wall
Matter, shortens the fermentation period of Chinese medicine, can more thoroughly be extracted by the active component in Chinese medicine simultaneously.In Jiang
Medicine active component is combined with fruit-vegerable ferment, makes Chinese medicine be easier to be accepted, simultaneously through ferment probiotic bacteria
Decomposition, nutrient substance therein is easier to the utilization that is absorbed by the body.
The comprehensive enzyme liquid of the present invention contains the nutritional labelings such as abundant vitamin, enzyme, mineral and aminoacid, tool
There are antibacterial action, antiinflammation, decomposition, antioxidation, blood can be purified, promote hyperplasia,
Intestinal can be cleared up again, to improving immunity of organisms, maintaining health to have important function.
Detailed description of the invention
Below in conjunction with being embodied as example, the present invention is described in further detail.
A kind of comprehensive enzyme liquid that there is fall three-hypers and improve immunity function, including following raw material:
Chinese medicine: Semen Cassiae 300g, Fructus Crataegi 400g, Pachyrhizua angulatus 600g, Ganoderma 200g, Herb Gynostemmae Pentaphylli 300g, Lepidinm meyenii Walp
200g；
Corn: Semen sojae atricolor 500g, Semen sojae atricolor 400g, Semen Sesami Nigrum 400g, Radix Et Rhizoma Fagopyri Tatarici 800g, Herba bromi japonici 300g；
Vegetable: Bulbus Allii 300g, Bulbus Allii Cepae 300g, Rhizoma Zingiberis Recens 100g, Thallus Laminariae (Thallus Eckloniae) 100g, Thallus Porphyrae 100g, Fructus Solani melongenae 200g,
Cauliflower 100g, Fructus Momordicae charantiae 100g, Herba Apii graveolentis 300g, Semen Phaseoli radiati Germinatus 100g, Fructus Cucumidis sativi 200g, Semen Maydis 100g, Rhizoma Dioscoreae 200g,
Radix Dauci Sativae 200g, white turnip 100g, Fructus Cucurbitae moschatae 100g, Fructus Lycopersici esculenti 200g, Tremella 200g, Flammulina velutiper (Fr.) Sing 200g,
Volvariella volvacea (Bull.Ex Franch.) Singer． 100g；
Fruit: Fructus Mali pumilae 500g, Citrullus vulgaris 300g, Fructus actinidiae chinensis 300g, pears 500g, Hylocereus undatus 700g.
The preparation technology of the present invention is as follows:
1) fruit-vegerable ferment fermentation
A) fruit and vegerable pretreatment
Being removed by Fructus actinidiae chinensis surface pubescence, various fruit and vegetables are cleaned in clear water, then carry out in Ozone Water
Streaming submergence sterilizes, and dries under aseptic condition, and Bulbus Allii, Hylocereus undatus peeling, Fructus Momordicae charantiae removes seed, and all fruit and vegerable are all with beating
Pulp grinder is pulled an oar.
B) fruit and vegerable enzymolysis
By above-mentioned steps A) mixing of the fruit, vegetable juice that processed, add the cellulase and 0.1% that mass fraction is 0.08%
Pectase, regulate pH to 4.0, under the conditions of 45 DEG C, enzymolysis 8 hours；It is added followed by the protease of 0.05%
α-amylase with 0.1%, regulates pH to 6.5, under the conditions of 40 DEG C, enzymolysis 5 hours；
C) fruit and vegerable fermentation
In above-mentioned steps B) the fruit and vegerable enzymolysis solution that processed is inoculated Candida utilis, beer yeast, addicted to yogurt
Bacillus and Lactobacillus plantarum, vaccination ways is that every kind of strain is by the inoculum concentration inoculating active bacterium number of 100g/t
1×109The active microbe powder of cfu/g, stirring and evenly mixing, seal, ferment 2 months under the conditions of 30 DEG C, obtain fruit-vegerable ferment.
2) corn ferment fermentation
A) corn pretreatment
It is mixed in stainless-steel pan after five kinds of corn are cleaned, steaming and decocting of opening fire after soaking 5h, maintains after boiling
2.5h, allows all corn steam moisture in the soft heart and pot and just boils dry, corn is aseptically spread out cooling
To room temperature.
B) fermented grain
In above-mentioned steps A) corn that processed adds the sterilized water of five times of raw material volume, inoculate Candida utilis ferment
Female and beer yeast, vaccination ways be every kind of strain be 1 × 10 by the inoculum concentration inoculating active bacterium number of 100g/t9cfu/g
Active microbe powder, stirring and evenly mixing, seal, under the conditions of 30 DEG C ferment 2 months, obtain corn ferment.
3) active Chinese drug component material extracts
A) buy first-class Ganoderma, Semen Cassiae, Fructus Crataegi, Pachyrhizua angulatus, Herb Gynostemmae Pentaphylli, Lepidinm meyenii Walp, after pulverizing, cross 40 mesh sieves；
B) raw material adding the edible ethanol of 70% until not having raw material 8cm, soaking 24h under room temperature and extracting,
Period shakes once every 3h, and residue is recovered by filtration, and gained filtrate is first time extracting solution；
C) above-mentioned steps B) residue obtained middle addition sterilized water, add mass fraction and be respectively the fiber of 0.1%
Element enzyme, pectase and protease carry out enzymolysis breaking cellular wall, and 40 DEG C are soaked 24h, and period shakes once every 3h, filter
Reclaiming residue, gained filtrate is second time extracting solution；
D) step C is repeated) once, gained filtrate is third time extracting solution；
E) merging three extracting solution, 45 DEG C of concentrating under reduced pressure are evaporated and obtain active Chinese drug component extract, and extract is with a small amount of
The edible ethanol of 50% is dissolved, standby.
4) allotment
By above-mentioned steps 1), 2) to fruit-vegerable ferment, corn ferment and step 3) active Chinese drug component that obtains carries
Take thing mixing, stir.
5) acetic fermentation
In above-mentioned steps 4) the mixing enzyme liquid that obtains adds Acetobacter pasteurianus, vaccination ways is every kind of strain
It is 1 × 10 by the inoculum concentration inoculating active bacterium number of 100g/t9The active microbe powder of cfu/g, seals after stirring, 30 DEG C
Under the conditions of ferment 2 months.
6) after-ripening
By above-mentioned steps 5) comprehensive enzyme that obtains filters, and filtrate adds mass fraction after weighing be 0.2% sweet
Leaf inulin, seals after mixing, and room temperature is placed 1 month.
7) filtration sterilization
By above-mentioned steps 6) comprehensive enzyme that obtains is degerming with the filtering with microporous membrane of 0.2 μm.
8) sterile filling
By above-mentioned steps 7) enzyme liquid that obtains carries out sterile filling and is packaged into enzyme liquid product.
The comprehensive enzyme liquid present invention prepared carries out zoopery, detects its fall three-hypers effect.
Blood pressure lowering is tested
The SD rat selecting body weight to be (300 ± 20) g, male and female half and half, first use fed standard chow one week, make
Animal adapts to environment and observation has no adverse reaction.40 SD rats are randomly divided into 4 groups, often group male and female half and half.
Blank group: normal diet is fed, and every day is by light water gavage once；
Hypertension model group: high-sugar-fat-diet (51% normal diet+15% Adeps Sus domestica+15% sucrose+15% yolk powder
+ 4% Sal) feed, alternately drink sugar-salt-water (sugar 4%, salt 1%) and fructose water (6%), every day is with common
Water gavage is once；
Ferment matched group: normal diet is fed, and every day, by ferment gavage once dosage was 1mL/100g body weight；
Ferment intervention group: high-sugar-fat-diet is fed, alternately drinks sugar-salt-water (sugar 4%, salt 1%) and fructose water
(6%), every day, by ferment gavage once dosage was 1mL/100g body weight；
Each group rat freely drinks water feed, feeds 8 weeks laggard row blood pressure measurements, is shown in Table 1.
Hypertension model group and blank group are carried out tail vein injection ferment, and dosage is 0.1mL/100g body
Weight, observation acute administration, on Hypertensive Rats and the impact of normal rat blood pressure, is shown in Table 2.
Blood lipid-reducing blood sugar-decreasing is tested
The kunming mice selecting body weight to be (20 ± 2g), after adaptability feeds one week, randomly draws 10 male and female each
The mice of half is Normal group, remaining mice overnight fasting, uses single high dose (60mg/kg) abdominal cavity note
Penetrating streptozotocin (STZ) modeling, Normal group injects isopyknic citric acid-sodium citrate buffer, and one
Zhou Hou, mice fasting 6 hours, tail vein trace takes hematometry animal model blood glucose value, more than or equal to 16mmol/L
Mice be the successful mice of modeling.20 successful diabetic mices of modeling are randomly divided into two groups, and often group male and female are each
Half, each group mouse feeding normal diet.Experimental group gastric infusion every day (enzyme liquid), dosage is 1mL/100g
Body weight, Normal group and model group give normal saline.After successive administration 8 weeks, mice fasting 6 hours,
Tail venous blood sampling, is centrifuged 10min in 3500r/min, separates serum, with each kit measurement serum blood glucose, glycerol
Three fat (TG), the concentration of cholesterol (TC), be shown in Table 3.
Impact on rat blood pressure after table 1 comprehensive enzyme gavage
| Group | Shrink pressure (mmHg) | Diastolic pressure (mmHg) |
| Blank group | 134.5±8.3 | 112.6±6.7 |
| Hypertension model group | 175.6±10.1 | 140.1±9.5 |
| Ferment matched group | 129.5±8.9 | 109.4±7.7 |
| Ferment intervention group | 147.7±9.3 | 125.6±8.4 |
The impact on rat blood pressure of table 2 acute administration
Table 3 comprehensive enzyme is on mouse blood sugar, the impact of blood fat
As can be seen from Table 1, the Hypertension Rats that high-sugar-fat-diet is induced by the comprehensive enzyme liquid that prepared by the present invention
There is certain preventive effect；As can be seen from Table 2, injection comprehensive enzyme liquid prepared by the present invention, hypertension is big
The blood pressure of Mus has certain decline, and the blood pressure drops of normal rat is less obvious；As can be seen from Table 3, the present invention
Prepared comprehensive enzyme liquid has certain downward effect to blood glucose, the blood fat of drug-induced diabetic mice.
The comprehensive enzyme liquid present invention prepared carries out case experiment, detects its fall three-hypers effect.
Table 4 case study on implementation (usage: every day sooner or later each 1 time, consumption: every time 30ml, take the cycle continuously:
90 days)
Table 4 case study on implementation situation
Shown by above experimental data, utilize the comprehensive enzyme liquid prepared by the present invention, to hypertension, hyperlipidemia and
Hyperglycemia has certain prevention and downward effect, simultaneously as it contains various fruits, vegetable, beans and paddy
Thing, balanced in nutrition comprehensively, by have fall three-hypers effect active Chinese drug component extract be combined with fruit-vegerable ferment, no
Chinese medicine is only made to be easier to accepted by the public, and the nutrient substance in the decomposition of microorganism, various raw materials
It is easier to the utilization that is absorbed by the body, this ferment of long-term drink, it is possible to increase immunity, prevention three-hypers, fall three-hypers,
Building body.
Above are only the detailed description of the invention of the present invention, but the design concept of the present invention is not limited thereto, all utilizations
This design carries out the change of unsubstantiality to the present invention, all should belong to the behavior invading scope.
Claims (9)
1. there is fall three-hypers and improve the comprehensive enzyme liquid of immunity function, it is characterised in that be main by following weight
The raw material of number is prepared from:
Chinese medicine: Semen Cassiae 3～5 parts, Fructus Crataegi 3～5 parts, Pachyrhizua angulatus 4～6 parts, Ganoderma 2～3 parts, Herb Gynostemmae Pentaphylli 2～
3 parts, Lepidinm meyenii Walp 2～3 parts；
Corn: Semen sojae atricolor 4～6 parts, Semen sojae atricolor 3～5 parts, Semen Sesami Nigrum 3～5 parts, Radix Et Rhizoma Fagopyri Tatarici 7～9 parts, Herba bromi japonici 2～
3 parts；
Vegetable: Bulbus Allii 2～3 parts, Bulbus Allii Cepae 2～3 parts, Rhizoma Zingiberis Recens 1～2 parts, Thallus Laminariae (Thallus Eckloniae) 1～2 parts, Thallus Porphyrae 1～2
Part, Fructus Solani melongenae 1～2 parts, cauliflower 1～2 parts, Fructus Momordicae charantiae 1～2 parts, Herba Apii graveolentis 2～3 parts, Semen Phaseoli radiati Germinatus 1～2 parts,
Fructus Cucumidis sativi 1～2 parts, Semen Maydis 1～2 parts, Rhizoma Dioscoreae 1～2 parts, Radix Dauci Sativae 1～2 parts, white turnip 1～2 parts, south
Melon 1～2 parts, Fructus Lycopersici esculenti 1～2 parts, Tremella 1～2 parts, Flammulina velutiper (Fr.) Sing 1～2 parts, Volvariella volvacea (Bull.Ex Franch.) Singer． 1～2 parts；
Fruit: Fructus Mali pumilae 4～6 parts, Citrullus vulgaris 3～5 parts, Fructus actinidiae chinensis 3～5 parts, pears 4～5 parts, Hylocereus undatus 5～7
Part.
2. the preparation method of comprehensive enzyme liquid described in claim 1, it is characterised in that comprise the steps:
A, by after all kinds of vegetables and fruit respective pretreatment pull an oar, then each slurry is mixed, add mass fraction
Be 0.05～the cellulase of 0.1% and 0.05～0.1% pectase carry out enzymolysis, be added followed by mass fraction
Be 0.02～the protease of 0.05% and 0.1% α-amylase carry out enzymolysis, connect in the fruit and vegerable enzymolysis solution obtained
Yeasts and lactic acid bacteria, stirring and evenly mixing, seal, uniform temperature bottom fermentation 2 months, obtain fruit-vegerable ferment；
B, by corn clean after be mixed in stainless-steel pan, steaming and decocting of opening fire after soaking 5h, after boiling maintain 2～
3h, allows all corn steam moisture in the soft heart and pot and just boils dry, aseptically spread out by corn and be cooled to
Room temperature, is subsequently adding the sterilized water of five times of raw material volume, inoculation yeast bacterium, stirring and evenly mixing, seals, uniform temperature
Bottom fermentation 2 months, obtains corn ferment；
C, extraction active Chinese drug component material；
D, mixing fruit-vegerable ferment, corn ferment and active Chinese drug component material, stir, and obtains mixing enzyme liquid,
Add acetic acid bacteria, seal after stirring, uniform temperature bottom fermentation 1～2 months, then filter, filtrate
Adding mass fraction after weighing is 0.2% stevioside, seals after mixing, and room temperature is placed 1 month；Then carry out
Membrane filtration is degerming, sterile filling.
3. the preparation method of comprehensive enzyme liquid as claimed in claim 2, it is characterised in that: described step c is extracted
Active Chinese drug component material comprises the steps:
C1: Ganoderma, Semen Cassiae, Fructus Crataegi, Pachyrhizua angulatus, Herb Gynostemmae Pentaphylli and Lepidinm meyenii Walp cross 40 mesh sieves after pulverizing, and add 70%
Edible ethanol until do not had raw material 5～10cm, soak 24h under room temperature and extract, period shakes one every 3h
Secondary, residue is recovered by filtration, gained filtrate is first time extracting solution；
Residue obtained middle addition sterilized water in c2:c1, add mass fraction be respectively 0.1% cellulase,
Pectase and protease carry out enzymolysis breaking cellular wall, and 40 DEG C are soaked 24h, and period shakes once every 3h, is recovered by filtration residual
Slag, gained filtrate is second time extracting solution；
C3: repeat c2, obtains third time extracting solution；
C4: merge three extracting solution, 45 DEG C of concentrating under reduced pressure are evaporated and obtain active Chinese drug component extract, and extract is with a small amount of
The edible ethanol of 50% is dissolved.
4. the preparation method of comprehensive enzyme liquid as claimed in claim 2, it is characterised in that: fine in described step a
The hydrolysis pH scope of dimension element enzyme and pectase is 3.0～4.5, and temperature range is 40～50 DEG C, and enzymolysis 5～10 is little
Time；The hydrolysis pH scope of protease and α-amylase is 6.0～7.5, and temperature range is 35～45 DEG C, carries out
Enzymolysis 3～7 hours.
5. the preparation method of comprehensive enzyme liquid as claimed in claim 2, it is characterised in that: described step a, b, d
In fermentation temperature be 28～32 DEG C.
6. the preparation method of comprehensive enzyme liquid as claimed in claim 2, it is characterised in that: in described step a, b
Yeast be Candida utilis and beer yeast, lactic acid bacteria is bacillus acidophilus and Lactobacillus plantarum, inoculation side
Formula be every kind of strain be 1 × 10 by the inoculum concentration inoculating active bacterium number of 100g/t9The active microbe powder of cfu/g.
7. the preparation method of comprehensive enzyme liquid as claimed in claim 2, it is characterised in that: in described step d
Acetic acid bacteria is Acetobacter pasteurianus, vaccination ways be every kind of strain be 1 by the inoculum concentration inoculating active bacterium number of 100g/t
×109The active microbe powder of cfu/g.
8. the preparation method of comprehensive enzyme liquid as claimed in claim 2, it is characterised in that: in described step d
The aperture of filter membrane is 0.1～0.2 μm.
9. the preparation method of comprehensive enzyme liquid as claimed in claim 2, it is characterised in that the vegetables in described step a
Dish and fruit pretreatment include: removed by Fructus actinidiae chinensis surface pubescence, and various fruit and vegetables are cleaned in clear water, then
In Ozone Water, carry out overflow-type submergence sterilization, dry under aseptic condition, the Bulbus Allii after sterilization, Hylocereus undatus peeling,
Fructus Momordicae charantiae removes seed.
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| CN106616846A (en) * | 2016-11-15 | 2017-05-10 | 安徽味仙食品有限公司 | Zinc supplementing edible salt |
| CN106667867A (en) * | 2016-12-08 | 2017-05-17 | 浙江百惠生物科技有限公司 | Green plum enzyme care solution |
| CN106722960A (en) * | 2017-01-06 | 2017-05-31 | 安徽妙奇树生物科技有限公司 | A kind of composite enzyme drink and preparation method thereof |
| CN106722769A (en) * | 2016-11-15 | 2017-05-31 | 安徽味仙食品有限公司 | A kind of the three high patients special-purpose salt |
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| CN112998231A (en) * | 2021-04-23 | 2021-06-22 | 绿优品(福建)健康科技研发中心有限公司 | Jelly capable of clearing intestines and expelling toxin and preparation method of jelly |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103750462A (en) * | 2014-01-21 | 2014-04-30 | 刘佛带 | Fruit and vegetable ferment beverage |
| CN105011128A (en) * | 2014-04-23 | 2015-11-04 | 广西南宁市林章中草药研究开发有限公司 | Plant essence enzyme oral solution capable of lowering hyperlipidemia, hypertension and hyperglycemia and preparation method thereof |
| CN105029603A (en) * | 2015-06-24 | 2015-11-11 | 陈琳仁 | Composite fresh flower, fruit, vegetable and herb enzyme, and preparation method and application thereof |
| CN105105268A (en) * | 2015-09-23 | 2015-12-02 | 杨万录 | Composite enzyme solution, preparation method and application thereof |
-
2016
- 2016-04-20 CN CN201610246864.0A patent/CN105918821A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103750462A (en) * | 2014-01-21 | 2014-04-30 | 刘佛带 | Fruit and vegetable ferment beverage |
| CN105011128A (en) * | 2014-04-23 | 2015-11-04 | 广西南宁市林章中草药研究开发有限公司 | Plant essence enzyme oral solution capable of lowering hyperlipidemia, hypertension and hyperglycemia and preparation method thereof |
| CN105029603A (en) * | 2015-06-24 | 2015-11-11 | 陈琳仁 | Composite fresh flower, fruit, vegetable and herb enzyme, and preparation method and application thereof |
| CN105105268A (en) * | 2015-09-23 | 2015-12-02 | 杨万录 | Composite enzyme solution, preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 严昕: "《好妈妈胜过好医生》", 31 January 2010, 海天出版社 * |
Cited By (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| CN107467644A (en) * | 2017-08-01 | 2017-12-15 | 张萌 | Promote ferment of digestion and protection gastric mucosa and preparation method thereof |
| CN107375784A (en) * | 2017-08-15 | 2017-11-24 | 晁伟岩 | It is capable of the preparation method of the oat mixed powder of three high drop |
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| CN108669392A (en) * | 2018-04-13 | 2018-10-19 | 张建欣 | A kind of beverage and preparation method thereof with healthcare function |
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| CN111558009A (en) * | 2019-01-29 | 2020-08-21 | 海南大学 | Composition with function of reducing high blood pressure, high blood sugar and high blood lipid and preparation method thereof |
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| CN112772908A (en) * | 2019-11-05 | 2021-05-11 | 湖南边城生物科技有限公司 | Preparation method of tea polyphenol-rich medicinal and edible plant enzyme |
| CN111357988A (en) * | 2020-04-22 | 2020-07-03 | 智昌药业(云南)有限公司 | Selenium-rich composite enzyme and preparation process thereof |
| CN111903884A (en) * | 2020-07-21 | 2020-11-10 | 国投中鲁果汁股份有限公司 | Processing method of stomach-invigorating and digestion-promoting potato enzyme beverage |
| CN112998231A (en) * | 2021-04-23 | 2021-06-22 | 绿优品(福建)健康科技研发中心有限公司 | Jelly capable of clearing intestines and expelling toxin and preparation method of jelly |
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Application publication date: 20160907 |