CN105902454A - Moringa compound essence for repairing and regenerating cells - Google Patents

Moringa compound essence for repairing and regenerating cells Download PDF

Info

Publication number
CN105902454A
CN105902454A CN201610485168.5A CN201610485168A CN105902454A CN 105902454 A CN105902454 A CN 105902454A CN 201610485168 A CN201610485168 A CN 201610485168A CN 105902454 A CN105902454 A CN 105902454A
Authority
CN
China
Prior art keywords
moringa
parts
extract
regeneration
essence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201610485168.5A
Other languages
Chinese (zh)
Other versions
CN105902454B (en
Inventor
杨曼生
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangdong Bailichen Biotechnology Co., Ltd.
Original Assignee
Jingxi Xiumeibiancheng Agricultural Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jingxi Xiumeibiancheng Agricultural Technology Co Ltd filed Critical Jingxi Xiumeibiancheng Agricultural Technology Co Ltd
Priority to CN201610485168.5A priority Critical patent/CN105902454B/en
Publication of CN105902454A publication Critical patent/CN105902454A/en
Application granted granted Critical
Publication of CN105902454B publication Critical patent/CN105902454B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/96Cosmetics or similar toilet preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toilet preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toilet preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toilet preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toilet preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toilet preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/72Cosmetics or similar toilet preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

Abstract

The invention relates to moringa compound essence for repairing and regenerating cells. The compound essence is characterized by being prepared from the following raw materials in parts by weight: 5-7 parts of moringa leaf extract, 2-4 parts of moringa seed oil, 3-5 parts of extract of peach kernels, radix paeoniae rubra, herba lycopi, rhizoma corydalis, safflower, pericarpium citri reticulatae, lindera aggregata and radix angelicae pubescentis, 1-3 parts of folium artemisiae argyi extract, 1-3 parts of achyranthes bidentata extract, 1-3 parts of phryma leptostachya extract, 5-10 parts of glycerinum, 2-4 parts of glycerin monostearate, 1-3 parts of triethanolamine, 5-10 parts of hyaluronic acid, 5-10 parts of collagen, 2-5 parts of 1,3-butanediol, 5-10 parts of lactic acid, 0.1 part of essential oil, 0.1 part of preservative and 24-65 parts of pure water. The moringa compound essence has the advantages of infiltrating deep layer of a face, promoting repairing and regeneration of facial cells, improving the anti-violet activity and preventing skin senescence, and is used for protecting skin safety since a certain antibacterial property is kept.

Description

A kind of Moringa compound recipe essence for cytothesis regeneration
[technical field]
The present invention relates to cosmetic field, particularly to a kind of Moringa compound recipe essence for cytothesis regeneration.
[background technology]
Skin is the same with other organs, along with the age is continuously increased, the most gradually tends to old and feeble.The aging of skin is a kind of normal existing As, the result of skin aging, in addition to making the physiological function of skin and going down, it is most important that makes the appearance of people there occurs change. Aging makes physical beauty lose lustre, and therefore, old and feeble appearance can produce negative effect to the psychology of people, and everybody is intended to keep appearance year Gently, perpetual youth.Prevention and delay skin aging are the important topics of cosmetic dermatology.The aging of skin is endogenous factor The exercising result common with exogenous stimulation factor.Endogenous factor is slowing down due to skin cell metabolism, the cutin of skin The thickening malnutrition causing skin of layer so that subcutaneous fat stores and gradually decreases, cell and fibrous tissue malnutrition, performance Decline, and make skin that wrinkle to occur.Extrinsic factor is because elastic fiber and the glue of direct sunlight meeting coup injury deep skin Former albumen, causes skin of face to become lax tarnish, ultraviolet irradiation, the most then makes skin darkening thicker, heavy then may result in Skin carcinoma, is to make skin do sth. in advance one of aging arch-criminal.So, to form and use high quality cosmetic particularly essence Good custom.
Essence, is the superfine product in skin care item, and composition is exquisite, effect is powerful, effect is notable, remains what it had Noble and mysterious.The effect of essence has anti-aging, crease-resistant, moisturizing, whitening, despeckle etc..The essence occurred currently on the market China's main effect of liquid is moisturizing, whitening and puts aging, has cytothesis regeneration function and the significant essence of effect is basic No.
[summary of the invention]
In view of foregoing, it is necessary to provide a kind of Moringa compound recipe essence for cytothesis regeneration, it is possible to penetrate into face Deep layer, promotes face's cytothesis regeneration, can also improve uvioresistant activity simultaneously, prevent skin aging, and keep certain Antibiotic property, the safety of protection skin.
For reaching above-mentioned purpose, the technical solution adopted in the present invention is: a kind of Moringa compound recipe elite for cytothesis regeneration Liquid, counts by weight and includes following raw material: moringa oleifera leaf extractive 5-7 part, seed oil of Moringa oleigera 2-4 part, native seven extract 3-5 Part, Folium Artemisiae Argyi extract 1-3 part, Radix Achyranthis Bidentatae extract 1-3 part, Herba speranskiae tuberculatae extract 1-3 part, glycerol 5-10 part, monostearate Glyceride 2-4 part, triethanolamine 1-3 part, hyaluronic acid 5-10 part, collagen protein 5-10 part, 1,3 butylene glycol 2-5 part, Lactic acid 5-10 part, quintessence oil 0.1 part, preservative 0.1 part and pure water 24-65 part.
In the present invention, as further illustrating, described moringa oleifera leaf extractive is prepared by following method: accurately weigh 30g's Leaf of Moringa, is dried 6-12 hour at 50-60 DEG C with infrared baking oven, pulverizes, and crosses 20 mesh sieve, is subsequently adding 200mL's Solvent, hot dipping 2-4 hour in 50-70 DEG C of hot bath, filter extraction filtrate, naturally cool to room temperature, then with 800-1000r/min Centrifugation 5-10 minute, take supernatant, add the dehydrated alcohol of 5-8 times of volume, stand 48 hours, with The centrifugation of 800-1000r/min 5-10 minute, takes precipitation, with the absolute ethanol washing 2 times of 200mL, uses infrared baking oven Within dry 12-24 hour, moringa oleifera leaf extractive is obtained at 50-60 DEG C.
In the present invention, as further illustrating, described solvent be distilled water water, methanol, ethanol, isopropanol, n-butyl alcohol, One in ethylene glycol, acetoneand ethyl acetate.
In the present invention, as further illustrating, described seed oil of Moringa oleigera is prepared by following method: i.e. weigh 100g moringa seeds core, Put into pulverizer to pulverize, cross 10 mesh sieves, put reflux, extract, device into, add 500mL analytical pure petroleum ether circumfluence distillation 2-5 time, 2-6h every time, merges extracting solution, puts into 50-80 DEG C after sucking filtration, and it is little that the vacuum drying oven of 0.05-0.15MPa concentrates 12-24 Time, obtain seed oil of Moringa oleigera.
In the present invention, as further illustrating, the described Moringa compound recipe essence for cytothesis regeneration is to golden yellow Portugal The antibiotic rate of grape coccus is 77.66-100%, is 75.81-91.65% to colibacillary antibiotic rate, antibacterial to Candida albicans Rate is 85.64-100%, and the antibiotic rate to bacillus pyocyaneus is 84.99-100%.
In the present invention, as further illustrating, the preparation of described a kind of Moringa compound recipe essence for cytothesis regeneration Method, it is characterised in that: concretely comprise the following steps:
Successively by load weighted moringa oleifera leaf extractive, seed oil of Moringa oleigera, native seven extracts, Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, thoroughly GUCAO extract, glycerol, glyceryl monostearate, triethanolamine, 1,3 butylene glycol, lactic acid and pure water put into emulsifying pot In, it is warming up to 60 DEG C, turn on agitator, stirs 40 minutes with the speed of 100r/min, is subsequently placed into hyaluronic acid and collagen Albumen, after stirring 20 minutes, is cooled to 45 DEG C while stirring, finally puts into quintessence oil and preservative, after stirring 10 minutes Prepare the Moringa compound recipe essence for cytothesis regeneration.
The effective ingredient of part material is as follows:
Moringa is drought-resistant, impoverishment tolerant, growth rapidly, strong adaptability, be the quick growing species of trees of subtropical and tropical zones.Leaf of Moringa Being conventional woody vegetables with tender fruit in India and south east asia, Moringa seed has water purification merit rich in oils and fats, edible, seed Energy.Leaf of Moringa, seed, bark, Moringa root etc. are folk tradition medicines, are used for keeping healthy and treat multiple disease.Therefore, peppery Wood is referred to as " tree of miracle ".
Moringa blade, really pod are rich in several mineral materials, vitamin, 20 kinds of aminoacid, 46 kinds of antioxygen elements and 36 kinds of scorching bodies the most anti- And mineral.Leaf of Moringa powder has blood sugar lowering, blood fat reducing, blood pressure lowering, antitumor, antioxidation, relieving constipation, diuresis, anthelmintic, improvement to sleep The effects such as dormancy, are eaten for a long time and can strengthen immune function of human body, slow down aging, prevention disease.Ayurveda thinks that Moringa can be pre- Anti-300 kinds of diseases.Moringa was subject to a lot of research institutions of developed country such as America and Europe and the concern of consumer and heat to hold in both hands the most in recent years. Often edible leaf of Moringa can enhancing immunity, toxin expelling, body shaping, aging resistance, anticancer and have multiple chronic and major disease Improve effect greatly.Leaf of Moringa is natural green food, the complete nutrients matter containing needed by human body, and it may replace compound dimension Raw element, calcium tablet, cod-liver oil etc..Especially hypertension, hyperlipidemia, diabetes, gout etc. there is good effect.Leaf of Moringa can Assist to improve, prevent disease, improve sleep, memory reinforcing, slow down aging, may further be used to treat liver, spleen, meridians Disease Deng privileged sites.It also has the treatment effect such as halitosis and relieving alcoholic intoxication.
In seed oil of Moringa oleigera, the kind composition of fatty acid is the most similar to olive oil, can be as table oil after polish.Due to Oil ben is the most oxidizable, has potent washing and makes bubble effect, is the excellent of soapmaking, cosmetics, lubricant, preservative and spice Raw material.
Soil seven prescription source: side goes out in " acute filthy disease Alioth " volume, and name is shown under " acute filthy disease pandect " volume.Medicine forms: Semen Persicae, red Chinese herbaceous peony, Herba Lycopi, corydalis tuber, Flos Carthami, Pericarpium Citri Reticulatae, the Radix Linderae, Radix Angelicae Pubescentis.
Folium Artemisiae Argyi makes Folium Artemisiae Argyi have another name called Artemisia argyi, Artemisia argyi Levl. et Van. var. argyi cv. Qiai, Radix Artemisia ordosicae, for the dried leaves of feverfew Chinese mugwort.There is warming the meridian for stopping bleeding, dispersing cold for relieving pain, Effect of wet down parasite killing.It is applicable to that deficient cold type is hemorrhage and stomachache, has substantially treatment for women's deficiency and coldness menoxenia, stomachache, metrorrhagia Effect.The ventable blood of Folium Artemisiae Argyi, warm meridians, while improving immunity of organisms, also there is effect of anti-bacteria and anti-virus.
Radix Achyranthis Bidentatae is elongated cylindrical, straight and upright or slightly bent, and long 15~70cm, diameter 0.4~1cm.Surface lark or light brown, There is the thin vertical wrinkle of micro-distortion, arrange sparse side root trace and the projection of hole skin sample of growing crosswise.Matter is the most crisp, frangibility, becomes after making moist Soft, section is smooth, light brown, slightly beautiful glossy in cutin sample, and center vascular bundle xylem is relatively big, yellow-white, and its periphery dissipates to be had Most HUANGBAI(sic) color dots.There are eliminating blood stasis and inducing menstruation, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, effect of conducting blood to flow downwards.
Herba speranskiae tuberculatae has another name called distiller’s yeast grass, Staggergrass etc..Perennial herb, reddish brown with stem color, without leaf, be dried, free from admixture person be Good.Annual herb flowers, produce the nations of China and India.Property happiness sunlight, be afraid of wet, heat-resisting can not resist cold, suitable be born in loose fertile micro-acid In soil, but the most barren-resistant.Adaptability is relatively strong, transplants and easily survives, and growth is rapidly.Seed also name Semen Impatientis, stem also name is deep Grass, all can be used as medicine, and has blood circulation promoting and blood stasis dispelling, diuresis removing toxic substances, deep effect of stimulating the menstrual flow.External application mashed by fresh grass, can control the swollen pain of furuncle, Insect-bite.
Glycerol is exactly glycerol, is as watery oils and fats, and skin easily absorbs, and 1,3-PD has good moisture-keeping function, Can serve as wetting agent.
Glyceryl monostearate, nonionic surfactant.Cosmetics and medicine unguentum are used as emulsifying agent.White waxy thin slice Or beadlet solid, water insoluble, mix through intense oscillations with hot water and be dispersed among in water.
Triethanolamine, colourless to pale yellow transparent thick liquid, micro-have ammonia taste, becomes colourless to faint yellow cubic system during low temperature Crystal.When being placed in air, color deepens gradually.Soluble in water, ethanol, acetone, glycerol and ethylene glycol etc., at cosmetics In be used as emulsifying agent, wetting agent, humidizer, thickening agent, PH poising agent.Triethanolamine is conventional emulsifying agent in cream preparation, By the cream products of triethanolamine emulsifying, there is mastic fine and smooth, the feature of mastic brilliant white, another triethanolamine and higher fatty acids or height The gel phase good stability that level fatty alcohol is formed, constant product quality, additional ingredients proportion can be held high.Triethanolamine is containing card The most frequently used nertralizer of the acid high-molecular gel such as ripple nurse, triethanolamine, by neutralizing with the carboxyl such as carbomer, forms stable height Molecular structure, reaches the application effect of thickening and moisturizing.
Hyaluronic acid is also known as alduronic acid, hyaluronic acid, and basic structure is by two dissacharide units D-Glucose aldehydic acid and N-acetyl Portugal The large-scale polysaccharide of osamine composition.Different from other mucopolysaccharide, its not sulfur-bearing.Its hyalomitome molecule can carry more than 500 times Moisture, for the optimal moisturizing ingredient recognized by current, be widely applied in skin care products and cosmetics.
Collagen protein is biopolymer, the main component in animal connective tissue, is also that mammal in-vivo content is most, divides The functional protein that cloth is the widest, accounts for the 25-30% of total protein, and some organism is even as high as more than 80%.Former albumen is because of tool There is good biocompatibility, biodegradable and biological activity, therefore at food, medicine, organizational project, cosmetics It is widely applied Deng field acquisition.
Lactic acid is a kind of carboxylic acid, and molecular formula is C3H6O3, it is a carboxylic acid containing hydroxyl, is therefore an alpha-hydroxy acid (AHA). Owing to lactic acid is a part for the intrinsic nature moisturizing factor of skin, therefore it is widely used as the moisturizing agent of many skin care item.
The method have the advantages that
1. a kind of Moringa compound recipe essence for cytothesis regeneration of the present invention has soft skin, nurses one's health cutin metabolism, repairs Cell regeneration, cell activity enhancing, keep skin elasticity and the effect of pliability, make skin glittering and translucent, full of vitality.This The total flavones in moringa oleifera leaf extractive in invention can remove aging horny layer of epidermis, promotes basal cell hyperplasia, repairs aging Collagen fiber, improve skin tension and elasticity.Adjust the proliferation and differentiation of horn cells, suppress keratinization process, stimulate and accelerate cell Maintenance and regeneration, stimulate hyperplasia, promotes blood capillary proliferation, accelerates blood circulation;Add native seven extracts can subtract The content of few peroxide MDA, improves the activity of superoxide dismutase SOD, eliminates what skin produced in metabolic processes Harmful substance, eliminates metabolic obstruction, promotes that cytothesis regeneration provides power-assisted for total flavones, further increases The metabolic speed of skin, improves skin surface gloss, allows skin more become clear, compacts.
2. a kind of Moringa compound recipe essence for cytothesis regeneration of the present invention has extremely strong non-oxidizability and uvioresistant is lived Property, protection skin is not encroached on by ultraviolet, resists the skin caused because of environmental radiation obscure, slows down the aging of Skin Cell Speed.On the one hand the dienoic acid in seed oil of Moringa oleigera and tetraenoic acid have the strongest absorption for shortwave and ultraviolet B radiation, have extremely strong Anti-ultraviolet stability;On the other hand flavone compound knot abundant in moringa oleifera leaf extractive and Folium Artemisiae Argyi extract is added The strong anti-oxidation that phenolic hydroxyl group in structure has, meanwhile, wormwood extract can effectively remove OH free radical, makes the essence of the present invention China's liquid has the strongest non-oxidizability, and seed oil of Moringa oleigera induction period is 9 times of olive oil so that the essence of the present invention Non-oxidizability is the most stable, extends the effective time of non-oxidizability.
3. a kind of Moringa compound recipe essence for cytothesis regeneration of the present invention has extremely strong antibiotic property, it is possible to well protect Skin safe, builds up one favourable barrier for skin.Isothiocyanate in moringa oleifera leaf extractive and seed oil of Moringa oleigera can destroy carefully The permeability of after birth, hinders the Repiration of antibacterial, has the strongest antibacterial activity for gram positive bacteria, dermatophytes; Add the 1,8-cineole in Folium Artemisiae Argyi extract, terpineol, spathulenol, caryophyllene oxide, Juniperus rigida Sieb.et Zucc. Camphora for multiple carefully Bacterium, fungus and virus have antibacterial action, synergism between the two, greatly strengthen the antibiotic property of essence, and peppery The polysaccharide contained the most very much in wood leaf extract, Herba speranskiae tuberculatae extract and Radix Achyranthis Bidentatae extract has filled up Folium Artemisiae Argyi extract for antibiotic property not Lasting shortcoming, is greatly improved the stability of antibacterial effect.
[detailed description of the invention]
Meter by weight:
Embodiment 1:
1. moringa oleifera leaf extractive, seed oil of Moringa oleigera, native seven extracts, wormwood extract, Radix Achyranthis Bidentatae extract and Herba speranskiae tuberculatae extract Preparation
Moringa oleifera leaf extractive is prepared by following method: accurately weigh the leaf of Moringa of 30g, is dried 6 with infrared baking oven little at 50 DEG C Time, to pulverize, cross 20 mesh sieve, be subsequently adding the distilled water of 100mL, hot dipping 2 hours in 50 DEG C of hot baths, filtration is taken out Take filtrate, naturally cool to room temperature, then the centrifugation 5 minutes with 800r/min, take supernatant, add 5 times of volumes Dehydrated alcohol, stands 48 hours, with the centrifugation 5 minutes of 800r/min, takes precipitation, washes with the dehydrated alcohol of 200mL Wash 2 times, with infrared baking oven 50 DEG C be dried within 12 hours, obtain moringa oleifera leaf extractive.
Seed oil of Moringa oleigera is prepared by following method: i.e. weigh 100g moringa seeds core, puts into pulverizer and pulverizes, crosses 10 mesh sieves, put into Reflux, extract, device, adds 500mL analytical pure petroleum ether circumfluence distillation 2 times, and extracting solution is merged, puts after sucking filtration by each 2h Entering 50 DEG C, the vacuum drying oven of 0.05MPa concentrates 12 hours, obtains seed oil of Moringa oleigera.
Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, native seven extracts and Herba speranskiae tuberculatae extract are prepared by following method: weigh pulverizing respectively Cross 20 mesh sieve Folium Artemisiae Argyi, Radix Achyranthis Bidentatae, soil seven and each 30g of Herba speranskiae tuberculatae, be respectively put in 200mL beaker, add 150mL steam Distilled water, is placed in electric-heated thermostatic water bath, and temperature controls at 80 DEG C, hot dipping 3 hours, and filtrate is put into additionally by sucking filtration 500mL large beaker in: repeat to extract 3 times by same method, merge 3 filtrates, be concentrated into 10-20mL by rotary evaporator, After being cooled to room temperature, add 60mL ethanol, at backlight, stand 24 hours, sucking filtration, filter cake washes 2 times with ethanol and ether successively, I.e. respectively obtain Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, native seven extracts and Herba speranskiae tuberculatae extract.
2. the preparation of Moringa compound recipe essence
Count by weight, successively 5 parts of moringa oleifera leaf extractive, 2 portions of seed oil of Moringa oleigeras, 3 portions of soil seven extracts, 1 portion of Folium Artemisiae Argyi are carried Take thing, 1 part of Radix Achyranthis Bidentatae extract, 1 part of Herba speranskiae tuberculatae extract, 2 parts of seed oil of Moringa oleigeras, 5 parts of glycerol, 2 parts of glyceryl monostearates, 1 part of triethanolamine, 1 part of 1,3 butylene glycol, 5 parts of lactic acid and 65 parts of pure water are put in emulsifying pot, are warming up to 60 DEG C, open Open agitator, stir 40 minutes with the speed of 100r/min, be subsequently placed into 5 parts of hyaluronic acids and 5 parts of collagen protein, stirring After 20 minutes, it is cooled to 45 DEG C while stirring, finally puts into 0.1 part of quintessence oil and 0.1 portion of preservative, after stirring 10 minutes i.e. The Moringa compound recipe essence for cytothesis regeneration can be prepared.
Embodiment 2:
1. moringa oleifera leaf extractive, seed oil of Moringa oleigera, native seven extracts, wormwood extract, Radix Achyranthis Bidentatae extract and Herba speranskiae tuberculatae extract Preparation
Moringa oleifera leaf extractive is prepared by following method: accurately weigh the leaf of Moringa of 30g, is dried 7 with infrared baking oven little at 55 DEG C Time, pulverize, cross 20 mesh sieve, be subsequently adding the ethanol of 120mL, hot dipping 2 hours in 50 DEG C of hot baths, filter extraction Filtrate, naturally cools to room temperature, then the centrifugation 6 minutes with 800r/min, takes supernatant, adds the nothing of 5 times of volumes Water-ethanol, stands 48 hours, with the centrifugation 6 minutes of 800r/min, takes precipitation, with the absolute ethanol washing of 200mL 2 times, with infrared baking oven 55 DEG C be dried within 14 hours, obtain moringa oleifera leaf extractive.
Seed oil of Moringa oleigera is prepared by following method: i.e. weigh 100g moringa seeds core, puts into pulverizer and pulverizes, crosses 10 mesh sieves, put into Reflux, extract, device, adds 500mL analytical pure petroleum ether circumfluence distillation 2 times, and extracting solution is merged, puts after sucking filtration by each 3h Entering 55 DEG C, the vacuum drying oven of 0.05MPa concentrates 14 hours, obtains seed oil of Moringa oleigera.
Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, native seven extracts and Herba speranskiae tuberculatae extract are prepared by following method: weigh pulverizing respectively Cross 20 mesh sieve Folium Artemisiae Argyi, Radix Achyranthis Bidentatae, soil seven and each 30g of Herba speranskiae tuberculatae, be respectively put in 200mL beaker, add 150mL steam Distilled water, is placed in electric-heated thermostatic water bath, and temperature controls at 80 DEG C, hot dipping 3 hours, and filtrate is put into additionally by sucking filtration 500mL large beaker in: repeat to extract 3 times by same method, merge 3 filtrates, be concentrated into 10-20mL by rotary evaporator, After being cooled to room temperature, add 60mL ethanol, at backlight, stand 24 hours, sucking filtration, filter cake washes 2 times with ethanol and ether successively, I.e. respectively obtain Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, native seven extracts and Herba speranskiae tuberculatae extract.
2. the preparation of Moringa compound recipe essence
Count by weight, successively by 5 parts of moringa oleifera leaf extractive, 2.5 parts of seed oil of Moringa oleigeras, 3.5 parts of soil seven extracts, 1.5 parts Folium Artemisiae Argyi extract, 1.5 parts of Radix Achyranthis Bidentatae extracts, 1.5 parts of Herba speranskiae tuberculatae extracts, 2 parts of seed oil of Moringa oleigeras, 6 parts of glycerol, 2 parts of lists are hard Glycerol, 1 part of triethanolamine, 1 part of 1,3 butylene glycol, 6 parts of lactic acid and 58 parts of pure water are put in emulsifying pot, rise Warm to 60 DEG C, turn on agitator, stirs 40 minutes with the speed of 100r/min, is subsequently placed into 6 parts of hyaluronic acids and 6 parts of glue Former albumen, after stirring 20 minutes, is cooled to 45 DEG C while stirring, finally puts into 0.1 part of quintessence oil and 0.1 portion of preservative, stirs The Moringa compound recipe essence for cytothesis regeneration is can be prepared by after mixing 10 minutes.
Embodiment 3:
1. moringa oleifera leaf extractive, seed oil of Moringa oleigera, native seven extracts, wormwood extract, Radix Achyranthis Bidentatae extract and Herba speranskiae tuberculatae extract Preparation
Moringa oleifera leaf extractive is prepared by following method: accurately weigh the leaf of Moringa of 30g, is dried 8 with infrared baking oven little at 65 DEG C Time, pulverize, cross 20 mesh sieve, be subsequently adding the methanol of 120mL, hot dipping 3 hours in 60 DEG C of hot baths, filter extraction Filtrate, naturally cools to room temperature, then the centrifugation 7 minutes with 850r/min, takes supernatant, adds the nothing of 6 times of volumes Water-ethanol, stands 48 hours, with the centrifugation 7 minutes of 850r/min, takes precipitation, with the absolute ethanol washing of 200mL 3 times, with infrared baking oven 65 DEG C be dried within 16 hours, obtain moringa oleifera leaf extractive.
Seed oil of Moringa oleigera is prepared by following method: i.e. weigh 100g moringa seeds core, puts into pulverizer and pulverizes, crosses 10 mesh sieves, put into Reflux, extract, device, adds 500mL analytical pure petroleum ether circumfluence distillation 3 times, and extracting solution is merged, puts after sucking filtration by each 3h Entering 60 DEG C, the vacuum drying oven of 0.1MPa concentrates 16 hours, obtains seed oil of Moringa oleigera.
Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, native seven extracts and Herba speranskiae tuberculatae extract are prepared by following method: weigh pulverizing respectively Cross 20 mesh sieve Folium Artemisiae Argyi, Radix Achyranthis Bidentatae, soil seven and each 30g of Herba speranskiae tuberculatae, be respectively put in 200mL beaker, add 150mL steam Distilled water, is placed in electric-heated thermostatic water bath, and temperature controls at 80 DEG C, hot dipping 3 hours, and filtrate is put into additionally by sucking filtration 500mL large beaker in: repeat to extract 3 times by same method, merge 3 filtrates, be concentrated into 10-20mL by rotary evaporator, After being cooled to room temperature, add 60mL ethanol, at backlight, stand 24 hours, sucking filtration, filter cake washes 2 times with ethanol and ether successively, I.e. respectively obtain Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, native seven extracts and Herba speranskiae tuberculatae extract.
2. the preparation of Moringa compound recipe essence
Count by weight, successively by 6 parts of moringa oleifera leaf extractive, 3 parts of seed oil of Moringa oleigeras, 3.5 parts of soil seven extracts, 1.5 parts of Chinese mugworts Leaf extract, 1.5 parts of Radix Achyranthis Bidentatae extracts, 1.5 parts of Herba speranskiae tuberculatae extracts, 3 parts of seed oil of Moringa oleigeras, 7 parts of glycerol, 3 parts of single tristearin Acid glyceride, 2 parts of triethanolamine, 2 parts of 1,3 butylene glycols, 7 parts of lactic acid and 48 parts of pure water are put in emulsifying pot, heat up To 60 DEG C, turn on agitator, stirs 40 minutes with the speed of 100r/min, is subsequently placed into 7 parts of hyaluronic acids and 7 parts of collagens Albumen, after stirring 20 minutes, is cooled to 45 DEG C while stirring, finally puts into 0.1 part of quintessence oil and 0.1 portion of preservative, stirring The Moringa compound recipe essence for cytothesis regeneration is can be prepared by after 10 minutes.
Embodiment 4:
1. moringa oleifera leaf extractive, seed oil of Moringa oleigera, native seven extracts, wormwood extract, Radix Achyranthis Bidentatae extract and Herba speranskiae tuberculatae extract Preparation
Moringa oleifera leaf extractive is prepared by following method: accurately weigh the leaf of Moringa of 30g, is dried 9 with infrared baking oven little at 70 DEG C Time, to pulverize, cross 20 mesh sieve, be subsequently adding the ethylene glycol of 150mL, hot dipping 3 hours in 65 DEG C of hot baths, filtration is taken out Take filtrate, naturally cool to room temperature, then the centrifugation 8 minutes with 900r/min, take supernatant, add 7 times of volumes Dehydrated alcohol, stands 48 hours, with the centrifugation 8 minutes of 900r/min, takes precipitation, washes with the dehydrated alcohol of 200mL Wash 3 times, with infrared baking oven 70 DEG C be dried within 18 hours, obtain moringa oleifera leaf extractive.
Seed oil of Moringa oleigera is prepared by following method: i.e. weigh 100g moringa seeds core, puts into pulverizer and pulverizes, crosses 10 mesh sieves, put into Reflux, extract, device, adds 500mL analytical pure petroleum ether circumfluence distillation 3 times, and extracting solution is merged, puts after sucking filtration by each 4h Entering 65 DEG C, the vacuum drying oven of 0.1MPa concentrates 18 hours, obtains seed oil of Moringa oleigera.
Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, native seven extracts and Herba speranskiae tuberculatae extract are prepared by following method: weigh pulverizing respectively Cross 20 mesh sieve Folium Artemisiae Argyi, Radix Achyranthis Bidentatae, soil seven and each 30g of Herba speranskiae tuberculatae, be respectively put in 200mL beaker, add 150mL steam Distilled water, is placed in electric-heated thermostatic water bath, and temperature controls at 80 DEG C, hot dipping 3 hours, and filtrate is put into additionally by sucking filtration 500mL large beaker in: repeat to extract 3 times by same method, merge 3 filtrates, be concentrated into 10-20mL by rotary evaporator, After being cooled to room temperature, add 60mL ethanol, at backlight, stand 24 hours, sucking filtration, filter cake washes 2 times with ethanol and ether successively, I.e. respectively obtain Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, native seven extracts and Herba speranskiae tuberculatae extract.
2. the preparation of Moringa compound recipe essence
Count by weight, successively by 6.5 parts of moringa oleifera leaf extractive, 3 portions of seed oil of Moringa oleigeras, 4 portions of soil seven extracts, 2 portions of Folium Artemisiae Argyis Extract, 2 parts of Radix Achyranthis Bidentatae extracts, 2 parts of Herba speranskiae tuberculatae extracts, 3 parts of seed oil of Moringa oleigeras, 8 parts of glycerol, 3 parts of glycerol monostearates Ester, 2 parts of triethanolamine, 2 parts of 1,3 butylene glycols, 8 parts of lactic acid and 42 parts of pure water are put in emulsifying pot, are warming up to 60 DEG C, Turn on agitator, stirs 40 minutes with the speed of 100r/min, is subsequently placed into 8 parts of hyaluronic acids and 8 parts of collagen protein, stirs After mixing 20 minutes, it is cooled to 45 DEG C while stirring, finally puts into 0.1 part of quintessence oil and 0.1 portion of preservative, after stirring 10 minutes Can be prepared by the Moringa compound recipe essence for cytothesis regeneration.
Embodiment 5:
1. moringa oleifera leaf extractive, seed oil of Moringa oleigera, native seven extracts, wormwood extract, Radix Achyranthis Bidentatae extract and Herba speranskiae tuberculatae extract Preparation
Moringa oleifera leaf extractive is prepared by following method: accurately weigh the leaf of Moringa of 30g, is dried 10 with infrared baking oven at 75 DEG C Hour, pulverize, cross 20 mesh sieve, be subsequently adding the ethyl acetate of 150mL, hot dipping 3.5 hours in 65 DEG C of hot baths, Filter extraction filtrate, naturally cool to room temperature, then the centrifugation 9 minutes with 950r/min, take supernatant, add 8 times The dehydrated alcohol of volume, stands 48 hours, with the centrifugation 9 minutes of 950r/min, takes precipitation, anhydrous with 200mL Washing with alcohol 4 times, with infrared baking oven 75 DEG C be dried within 20 hours, obtain moringa oleifera leaf extractive.
Seed oil of Moringa oleigera is prepared by following method: i.e. weigh 100g moringa seeds core, puts into pulverizer and pulverizes, crosses 10 mesh sieves, put into Reflux, extract, device, adds 500mL analytical pure petroleum ether circumfluence distillation 4 times, and extracting solution is merged, puts after sucking filtration by each 5h Entering 70 DEG C, the vacuum drying oven of 0.12MPa concentrates 20 hours, obtains seed oil of Moringa oleigera.
Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, native seven extracts and Herba speranskiae tuberculatae extract are prepared by following method: weigh pulverizing respectively Cross 20 mesh sieve Folium Artemisiae Argyi, Radix Achyranthis Bidentatae, soil seven and each 30g of Herba speranskiae tuberculatae, be respectively put in 200mL beaker, add 150mL steam Distilled water, is placed in electric-heated thermostatic water bath, and temperature controls at 80 DEG C, hot dipping 3 hours, and filtrate is put into additionally by sucking filtration 500mL large beaker in: repeat to extract 3 times by same method, merge 3 filtrates, be concentrated into 10-20mL by rotary evaporator, After being cooled to room temperature, add 60mL ethanol, at backlight, stand 24 hours, sucking filtration, filter cake washes 2 times with ethanol and ether successively, I.e. respectively obtain Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, native seven extracts and Herba speranskiae tuberculatae extract.
2. the preparation of Moringa compound recipe essence
Count by weight, successively by 6.5 parts of moringa oleifera leaf extractive, 3.5 parts of seed oil of Moringa oleigeras, 4.5 parts of soil seven extracts, 2.5 Part Folium Artemisiae Argyi extract, 2.5 parts of Radix Achyranthis Bidentatae extracts, 2.5 parts of Herba speranskiae tuberculatae extracts, 4 parts of seed oil of Moringa oleigeras, 9 parts of glycerol, 4 parts of lists Tristerin, 3 parts of triethanolamine, 3 parts of 1,3 butylene glycols, 9 parts of lactic acid and 32 parts of pure water are put in emulsifying pot, It is warming up to 60 DEG C, turn on agitator, stirs 40 minutes with the speed of 100r/min, is subsequently placed into 9 parts of hyaluronic acids and 9 parts Collagen protein, after stirring 20 minutes, is cooled to 45 DEG C while stirring, finally puts into 0.1 part of quintessence oil and 0.1 portion of preservative, The Moringa compound recipe essence for cytothesis regeneration is can be prepared by after stirring 10 minutes.
Embodiment 6:
1. moringa oleifera leaf extractive, seed oil of Moringa oleigera, native seven extracts, wormwood extract, Radix Achyranthis Bidentatae extract and Herba speranskiae tuberculatae extract Preparation
Moringa oleifera leaf extractive is prepared by following method: accurately weigh the leaf of Moringa of 30g, is dried 12 with infrared baking oven at 80 DEG C Hour, to pulverize, cross 20 mesh sieve, be subsequently adding the acetone of 200mL, hot dipping 4 hours in 70 DEG C of hot baths, filtration is taken out Take filtrate, naturally cool to room temperature, then the centrifugation 10 minutes with 1000r/min, take supernatant, add 8 times of volumes Dehydrated alcohol, stand 48 hours, with the centrifugation 10 minutes of 1000r/min, take precipitation, by the anhydrous second of 200mL Alcohol wash 5 times, with infrared baking oven 80 DEG C be dried within 24 hours, obtain moringa oleifera leaf extractive.
Seed oil of Moringa oleigera is prepared by following method: i.e. weigh 100g moringa seeds core, puts into pulverizer and pulverizes, crosses 10 mesh sieves, put into Reflux, extract, device, adds 500mL analytical pure petroleum ether circumfluence distillation 5 times, and extracting solution is merged, puts after sucking filtration by each 6h Entering 80 DEG C, the vacuum drying oven of 0.15MPa concentrates 24 hours, obtains seed oil of Moringa oleigera.
Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, native seven extracts and Herba speranskiae tuberculatae extract are prepared by following method: weigh pulverizing respectively Cross 20 mesh sieve Folium Artemisiae Argyi, Radix Achyranthis Bidentatae, soil seven and each 30g of Herba speranskiae tuberculatae, be respectively put in 200mL beaker, add 150mL steam Distilled water, is placed in electric-heated thermostatic water bath, and temperature controls at 80 DEG C, hot dipping 3 hours, and filtrate is put into additionally by sucking filtration 500mL large beaker in: repeat to extract 3 times by same method, merge 3 filtrates, be concentrated into 10-20mL by rotary evaporator, After being cooled to room temperature, add 60mL ethanol, at backlight, stand 24 hours, sucking filtration, filter cake washes 2 times with ethanol and ether successively, I.e. respectively obtain Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, native seven extracts and Herba speranskiae tuberculatae extract.
2. the preparation of Moringa compound recipe essence
Count by weight, successively 7 parts of moringa oleifera leaf extractive, 4 portions of seed oil of Moringa oleigeras, 5 portions of soil seven extracts, 3 portions of Folium Artemisiae Argyis are carried Take thing, 3 parts of Radix Achyranthis Bidentatae extracts, 3 parts of Herba speranskiae tuberculatae extracts, 4 parts of seed oil of Moringa oleigeras, 10 parts of glycerol, 4 parts of glyceryl monostearates, 3 parts of triethanolamine, 3 parts of 1,3 butylene glycols, 10 parts of lactic acid and 24 parts of pure water are put in emulsifying pot, are warming up to 60 DEG C, Turn on agitator, stirs 40 minutes with the speed of 100r/min, is subsequently placed into 10 parts of hyaluronic acids and 10 parts of collagen protein, After stirring 20 minutes, it is cooled to 45 DEG C while stirring, finally puts into 0.1 part of quintessence oil and 0.1 portion of preservative, stir 10 minutes After can be prepared by for cytothesis regeneration Moringa compound recipe essence.
Comparative example 1:
Test to improving and remove cicatrix:
Being measured microscopically of band shooting is used to change without cicatrix.Test object is 50 volunteers (25 women, 25 male), , between 15-65 year, there is scar at age.Test is carried out under the supervision of dermatologist.Contrast does not uses essence and use One day twice morning of product of the present invention and evening, spread upon scarring areas, after using 45 days continuously, measure its repair rate, contrast The results are shown in Table 1.
Table 1:
Mild scar Moderate cicatrix Severe cicatrix
Do not use essence 85% 65% 25%
Embodiment 1 100% 70% 40%
Embodiment 2 100% 72% 43%
Embodiment 3 100% 77% 50%
Embodiment 4 100% 85% 55%
Embodiment 5 100% 80% 52%
Embodiment 6 100% 80% 50%
Table 1 result shows: use the cicatrix repair rate of the volunteer implementing 1-6 essence to be significantly larger than the will not using essence The cicatrix repair rate of hope person, wherein mild scar repair rate is arranged as from high to low: embodiment 1=embodiment 2=embodiment 3=is real Execute example 4=embodiment 5=embodiment 6 > do not use essence;Moderate cicatrix repair rate is arranged as from high to low: embodiment 4 > implement Example 5=embodiment 6 > embodiment 3 > embodiment 2 > embodiment 1 > do not use essence;Severe cicatrix repair rate is arranged as from high to low: Embodiment 4 > embodiment 5 > embodiment 6=embodiment 3 > embodiment 2 > embodiment 1 > do not use essence.
Comparative example 2:
Take and do not use essence and embodiment 1-6 sample to measure mensuration at maximum absorption wavelength 212nm at ultraviolet spectrophotometer Absorbance after 10min and 120min, the results are shown in Table 2.
Table 2:
Table 2 result shows: the sample using embodiment 1-6 is stronger than the absorbance of the sample not using essence, and 120min Being more or less the same with the result of the absorbance of 10min, the absorbance of 10min test is arranged as from high to low: embodiment 4 > embodiment 5 > embodiment 6 > embodiment 3 > embodiment 2 > embodiment 1 > do not use essence;The absorbance of 120min test arranges from high to low For: embodiment 4 > embodiment 5 > embodiment 6 > embodiment 3 > embodiment 2 > embodiment 1 > do not use essence.
Comparative example 3:
The sample being not added with essence and each embodiment of interpolation is carried out antibiotic property test, and its antibiotic rate the results are shown in Table 3.
Table 3:
Table 3 result shows: staphylococcus aureus, escherichia coli, Candida albicans, bacillus pyocyaneus are had relatively by embodiment 1-6 Good antibacterial effect, does not uses the sample of essence to staphylococcus aureus, escherichia coli, Candida albicans, bacillus pyocyaneus There is no antibacterial effect.To the antibiotic rate of staphylococcus aureus being arranged as from high to low: embodiment 4=embodiment 5=embodiment 6 > embodiment 3 > embodiment 2 > embodiment 1 > do not use essence;To colibacillary antibiotic rate being arranged as from high to low: real Execute example 4 > embodiment 5 > embodiment 6 > embodiment 3 > embodiment 2 > embodiment 1 > do not use essence;Antibacterial to Candida albicans Rate being arranged as from high to low: embodiment 3=embodiment 4=embodiment 5=embodiment 6 > embodiment 2 > embodiment 1 > do not use elite Liquid;To the antibiotic rate of bacillus pyocyaneus being arranged as from high to low: embodiment 4=embodiment 5=embodiment 6 > embodiment 3 > embodiment 2 > embodiment 1 > do not use essence;
In a kind of better embodiment of the present invention
1. moringa oleifera leaf extractive, seed oil of Moringa oleigera, native seven extracts, wormwood extract, Radix Achyranthis Bidentatae extract and Herba speranskiae tuberculatae extract Preparation
Moringa oleifera leaf extractive is prepared by following method: accurately weigh the leaf of Moringa of 30g, is dried 9 with infrared baking oven little at 70 DEG C Time, to pulverize, cross 20 mesh sieve, be subsequently adding the ethylene glycol of 150mL, hot dipping 3 hours in 65 DEG C of hot baths, filtration is taken out Take filtrate, naturally cool to room temperature, then the centrifugation 8 minutes with 900r/min, take supernatant, add 7 times of volumes Dehydrated alcohol, stands 48 hours, with the centrifugation 8 minutes of 900r/min, takes precipitation, washes with the dehydrated alcohol of 200mL Wash 3 times, with infrared baking oven 70 DEG C be dried within 18 hours, obtain moringa oleifera leaf extractive.
Seed oil of Moringa oleigera is prepared by following method: i.e. weigh 100g moringa seeds core, puts into pulverizer and pulverizes, crosses 10 mesh sieves, put into Reflux, extract, device, adds 500mL analytical pure petroleum ether circumfluence distillation 3 times, and extracting solution is merged, puts after sucking filtration by each 4h Entering 65 DEG C, the vacuum drying oven of 0.1MPa concentrates 18 hours, obtains seed oil of Moringa oleigera.
Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, native seven extracts and Herba speranskiae tuberculatae extract are prepared by following method: weigh pulverizing respectively Cross 20 mesh sieve Folium Artemisiae Argyi, Radix Achyranthis Bidentatae, soil seven and each 30g of Herba speranskiae tuberculatae, be respectively put in 200mL beaker, add 150mL steam Distilled water, is placed in electric-heated thermostatic water bath, and temperature controls at 80 DEG C, hot dipping 3 hours, and filtrate is put into additionally by sucking filtration 500mL large beaker in: repeat to extract 3 times by same method, merge 3 filtrates, be concentrated into 10-20mL by rotary evaporator, After being cooled to room temperature, add 60mL ethanol, at backlight, stand 24 hours, sucking filtration, filter cake washes 2 times with ethanol and ether successively, I.e. respectively obtain Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, native seven extracts and Herba speranskiae tuberculatae extract.
2. the preparation of Moringa compound recipe essence
Count by weight, successively by 6.5 parts of moringa oleifera leaf extractive, 3 portions of seed oil of Moringa oleigeras, 4 portions of soil seven extracts, 2 portions of Folium Artemisiae Argyis Extract, 2 parts of Radix Achyranthis Bidentatae extracts, 2 parts of Herba speranskiae tuberculatae extracts, 3 parts of seed oil of Moringa oleigeras, 8 parts of glycerol, 3 parts of glycerol monostearates Ester, 2 parts of triethanolamine, 2 parts of 1,3 butylene glycols, 8 parts of lactic acid and 42 parts of pure water are put in emulsifying pot, are warming up to 60 DEG C, Turn on agitator, stirs 40 minutes with the speed of 100r/min, is subsequently placed into 8 parts of hyaluronic acids and 8 parts of collagen protein, stirs After mixing 20 minutes, it is cooled to 45 DEG C while stirring, finally puts into 0.1 part of quintessence oil and 0.1 portion of preservative, after stirring 10 minutes Can be prepared by the Moringa compound recipe essence for cytothesis regeneration.
Described above is the detailed description for the preferable possible embodiments of the present invention, but embodiment is not limited to the special of the present invention Profit application range, the equal change completed under the technical spirit suggested by all present invention or modification change, the present invention all should be belonged to Contained the scope of the claims.

Claims (6)

1. the Moringa compound recipe essence for cytothesis regeneration, it is characterised in that: count by weight and include following raw material: Moringa oleifera leaf extractive 5-7 part, seed oil of Moringa oleigera 2-4 part, native seven extract 3-5 parts, Folium Artemisiae Argyi extract 1-3 part, Radix Acanthopanacis Bidentatae extraction Thing 1-3 part, Herba speranskiae tuberculatae extract 1-3 part, glycerol 5-10 part, glyceryl monostearate 2-4 part, triethanolamine 1-3 part, Hyaluronic acid 5-10 part, collagen protein 5-10 part, 1,3 butylene glycol 2-5 part, lactic acid 5-10 part, quintessence oil 0.1 part, anticorrosion Agent 0.1 part and pure water 24-65 part.
A kind of Moringa compound recipe essence for cytothesis regeneration the most according to claim 1, it is characterised in that: described Moringa oleifera leaf extractive prepared by following method: accurately weigh the leaf of Moringa of 30g, with infrared baking oven at 50-80 DEG C be dried 6-12 Hour, pulverize, cross 20 mesh sieve, be subsequently adding the solvent of 100-200mL, hot dipping 2-4 hour in 50-70 DEG C of hot bath, Filter extraction filtrate, naturally cool to room temperature, then centrifugation 5-10 minute with 800-1000r/min, take supernatant, Adding the dehydrated alcohol of 5-8 times of volume, stand 48 hours, with centrifugation 5-10 minute of 800-1000r/min, it is heavy to take Form sediment, with absolute ethanol washing 2-5 time of 200mL, within dry 12-24 hour, obtain leaf of Moringa with infrared baking oven at 50-80 DEG C and carry Take thing.
A kind of Moringa compound recipe essence for cytothesis regeneration the most according to claim 2, it is characterised in that: described Solvent be the one in water, methanol, ethanol, isopropanol, n-butyl alcohol, ethylene glycol, acetoneand ethyl acetate.
A kind of Moringa compound recipe essence for cytothesis regeneration the most according to claim 1, it is characterised in that: described Seed oil of Moringa oleigera prepared by following method: i.e. weigh 100g moringa seeds core, put into pulverizer pulverize, cross 10 mesh sieves, put into back Stream extractor, adds 500mL analytical pure petroleum ether circumfluence distillation 2-5 time, and extracting solution is merged, after sucking filtration by each 2-6h Putting into 50-80 DEG C, the vacuum drying oven of 0.05-0.15MPa concentrates 12-24 hour, obtains seed oil of Moringa oleigera.
A kind of Moringa compound recipe essence for cytothesis regeneration the most according to claim 1, it is characterised in that: described The Moringa compound recipe essence for cytothesis regeneration be 77.66-100% to the antibiotic rate of staphylococcus aureus, to large intestine bar The antibiotic rate of bacterium is 75.81-91.65%, and the antibiotic rate to Candida albicans is 85.64-100%, to the antibiotic rate of bacillus pyocyaneus is 84.99-100%.
6. according to the preparation of a kind of Moringa compound recipe essence for cytothesis regeneration described in any one in claim 1-5 Method, it is characterised in that: concretely comprise the following steps:
Successively by load weighted moringa oleifera leaf extractive, seed oil of Moringa oleigera, native seven extracts, Folium Artemisiae Argyi extract, Radix Achyranthis Bidentatae extract, thoroughly GUCAO extract, glycerol, glyceryl monostearate, triethanolamine, 1,3 butylene glycol, lactic acid and pure water put into emulsifying pot In, it is warming up to 60 DEG C, turn on agitator, stirs 40 minutes with the speed of 100r/min, is subsequently placed into hyaluronic acid and collagen Albumen, after stirring 20 minutes, is cooled to 45 DEG C while stirring, finally puts into quintessence oil and preservative, after stirring 10 minutes Prepare the Moringa compound recipe essence for cytothesis regeneration.
CN201610485168.5A 2016-06-27 2016-06-27 One kind being used for the regenerated Moringa compound Essence of cell repair Active CN105902454B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610485168.5A CN105902454B (en) 2016-06-27 2016-06-27 One kind being used for the regenerated Moringa compound Essence of cell repair

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610485168.5A CN105902454B (en) 2016-06-27 2016-06-27 One kind being used for the regenerated Moringa compound Essence of cell repair

Publications (2)

Publication Number Publication Date
CN105902454A true CN105902454A (en) 2016-08-31
CN105902454B CN105902454B (en) 2019-06-04

Family

ID=56759742

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610485168.5A Active CN105902454B (en) 2016-06-27 2016-06-27 One kind being used for the regenerated Moringa compound Essence of cell repair

Country Status (1)

Country Link
CN (1) CN105902454B (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106265456A (en) * 2016-09-30 2017-01-04 中国热带农业科学院农产品加工研究所 A kind of Moringa facial film and preparation method thereof
CN106924078A (en) * 2017-02-17 2017-07-07 德宏州春雪化妆品销售有限公司 A kind of Moringa frost, Moringa breast and preparation method thereof
CN107184621A (en) * 2017-05-16 2017-09-22 云南省林业科学院 A kind of extracting method of leaf of Moringa active ingredient and its application
CN108926505A (en) * 2018-08-17 2018-12-04 卢莺莺 A kind of exfoliating skin care scrub cream and preparation method thereof
CN110507569A (en) * 2019-08-09 2019-11-29 湖北大学 Moringa seeds water extract, its extracting method and cosmetics
CN112675084A (en) * 2020-12-23 2021-04-20 昆明颜臻青生物科技有限公司 Moringa oleifera extract for promoting collagen secretion and application thereof

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022135884A1 (en) * 2020-12-25 2022-06-30 Unilever Ip Holdings B.V. Personal care composition

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104306432A (en) * 2014-10-31 2015-01-28 徐淳铣 Natural drug preparation for bath and skin care and preparation method thereof
CN104800128A (en) * 2015-05-06 2015-07-29 广州神采化妆品有限公司 Preservative-free multi-effect repair essence and preparation method thereof
CN105434233A (en) * 2015-12-08 2016-03-30 广州市花安堂生物科技有限公司 Keratin repair essence and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104306432A (en) * 2014-10-31 2015-01-28 徐淳铣 Natural drug preparation for bath and skin care and preparation method thereof
CN104800128A (en) * 2015-05-06 2015-07-29 广州神采化妆品有限公司 Preservative-free multi-effect repair essence and preparation method thereof
CN105434233A (en) * 2015-12-08 2016-03-30 广州市花安堂生物科技有限公司 Keratin repair essence and preparation method thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106265456A (en) * 2016-09-30 2017-01-04 中国热带农业科学院农产品加工研究所 A kind of Moringa facial film and preparation method thereof
CN106924078A (en) * 2017-02-17 2017-07-07 德宏州春雪化妆品销售有限公司 A kind of Moringa frost, Moringa breast and preparation method thereof
CN107184621A (en) * 2017-05-16 2017-09-22 云南省林业科学院 A kind of extracting method of leaf of Moringa active ingredient and its application
CN108926505A (en) * 2018-08-17 2018-12-04 卢莺莺 A kind of exfoliating skin care scrub cream and preparation method thereof
CN108926505B (en) * 2018-08-17 2021-05-14 恒冠湄颜健康产业(广州)有限公司 Skin-care scrub cream for removing cutin and preparation method thereof
CN110507569A (en) * 2019-08-09 2019-11-29 湖北大学 Moringa seeds water extract, its extracting method and cosmetics
CN112675084A (en) * 2020-12-23 2021-04-20 昆明颜臻青生物科技有限公司 Moringa oleifera extract for promoting collagen secretion and application thereof

Also Published As

Publication number Publication date
CN105902454B (en) 2019-06-04

Similar Documents

Publication Publication Date Title
CN105902454A (en) Moringa compound essence for repairing and regenerating cells
KR101373636B1 (en) Composition for improving condition of skin and scalp containing fermented extracts of herb mixture
CN102113987B (en) Cosmetic containing natural plant extractives and preparation method thereof
CN104434618B (en) Have whitening, nti-freckle concurrently and print nine grass green frosts of effect and preparation method thereof
CN107937176A (en) A kind of high-efficiency antioxidant anti-acne handmade soap
KR102038650B1 (en) Composite of Natural soap for skin cure and Method of manufacturing thereof
CN106236644A (en) It is a kind of that water is tender runs through essence
CN104288061B (en) A kind of beautifying skin and preserving health massage liquid
CN105125466A (en) Freckle removing night cream and preparing method thereof
CN105997827A (en) Compound camellia oil moisturizer and preparation method thereof
KR100867514B1 (en) How to manufacture a soap from lithospermum erythrorhizon
CN104644528A (en) Preparation method and application of novel edible moisturizing nutritional ointment
CN106913495A (en) Profit maintenance skin essence dew and preparation method thereof
KR102288724B1 (en) Multi functional shampoo for pet comprising functional complex composition for improving function of anti-bacterial, sterilization, anti-inflammation and skin soothing, and enhancing skin immune and manufacturing method thereof
CN106727159B (en) Spot-fading whitening mud mask and preparation method thereof
CN104721121A (en) Skin care type cosmetic
CN108567003A (en) A kind of ultra micro composite mulberry leaf tea powder and preparation method thereof
KR101203394B1 (en) Scrub cosmetic composition containing shiitake
CN113908087A (en) Natural moisturizing combined extract, preparation method and application thereof
KR101685686B1 (en) Scrub Cosmetic Composition Comprising Solar Salt
CN103599054A (en) Mask containing peanut protein polypeptide and preparation method thereof
CN109646359B (en) Rose-agaric mud membrane paste with effects of cleaning, purifying, maintaining beauty and keeping young and preparation method thereof
KR102137951B1 (en) Cosmetic composition with skin soothing effect comprising mushroom complex extract, and manufacturing method thereof
CN105106085A (en) Chinese medicinal herb sunscreen cream containing attapulgite
KR20160121293A (en) Atopic skin cosmetic composition and a method of manufacturing the improved

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right
TA01 Transfer of patent application right

Effective date of registration: 20190508

Address after: 317000 No. 21 Dongfa Road, Shaojiadu Street, Linhai City, Taizhou City, Zhejiang Province

Applicant after: Han Zaiman

Address before: 533899 No. 18, Binshan District, East Road, Xinjing Town, Jingxi City, Baise City, Guangxi Zhuang Autonomous Region

Applicant before: Jingxi Xiumei Biancheng Agricultural Science and Technology Co., Ltd.

GR01 Patent grant
GR01 Patent grant
TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20191112

Address after: 510880 floor 1 and 2, No.6 Qiyuan Avenue, Huashan Town, Huadu District, Guangzhou City, Guangdong Province

Patentee after: Guangdong Bailichen Biotechnology Co., Ltd.

Address before: 317000 No. 21 Dongfa Road, Shaojiadu Street, Linhai City, Taizhou City, Zhejiang Province

Patentee before: Han Zaiman

PE01 Entry into force of the registration of the contract for pledge of patent right
PE01 Entry into force of the registration of the contract for pledge of patent right

Denomination of invention: Moringa compound essence for cell repair and regeneration

Effective date of registration: 20211117

Granted publication date: 20190604

Pledgee: Conghua sub branch of Guangzhou Rural Commercial Bank Co.,Ltd.

Pledgor: GUANGDONG BAILICHEN BIOTECHNOLOGY Co.,Ltd.

Registration number: Y2021440000338