CN105902409B - One kind is mild and has thixotropic toothpaste - Google Patents
One kind is mild and has thixotropic toothpaste Download PDFInfo
- Publication number
- CN105902409B CN105902409B CN201610315810.5A CN201610315810A CN105902409B CN 105902409 B CN105902409 B CN 105902409B CN 201610315810 A CN201610315810 A CN 201610315810A CN 105902409 B CN105902409 B CN 105902409B
- Authority
- CN
- China
- Prior art keywords
- toothpaste
- agent
- thixotropic
- mildly
- variety
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
The present invention provides a kind of toothpaste that mild thixotropy is good, the toothpaste be by by weight percentage moisturizer 15-50%, main rubbing agent 10-30%, rubbing agent 0-20%, thixotropic agent 0.5-3.0%, thickener 0.1-2.0%, foaming agent 1.0-10%, corrigent 5.0-15%, fragrance 0.1-3.0%, bacteriostatic agent 0.02-3.0% and balance deionized water is helped to constitute；Wherein main rubbing agent is the cellulose or microcrystalline cellulose porous granule of partial size 70-400um；Helping rubbing agent is one of calcium carbonate, calcium phosphate dibasic dihydrate, calcium gluconate or a variety of；Thixotropic agent is that first xanthan gum is distributed in water, add the microcrystalline cellulose porous granule that partial size is 0.1-20um, homogeneous is to keeping its fully dispersed, then spray drying is formed, weight percent of the xanthan gum in thixotropic agent is 10-20%, and weight percent of the microcrystalline cellulose porous granule in thixotropic agent is 80-90%.Toothpaste of the invention, cleaning effect is excellent, it is few to wear to tooth enamel, and thixotropy is good, and when brushing teeth, lotion will not be with falling under foam.The present invention also provides a kind of preparation methods of above-mentioned toothpaste.
Description
Technical field
The present invention relates to a kind of toothpaste more particularly to a kind of pair of tooth enamel to wear few mild toothpaste, more specifically
It is related to a kind of pair of tooth enamel abrasion less and can increase the good toothpaste of the thixotropic mild thixotropy of product.The invention further relates to
A kind of preparation method for the toothpaste that above-mentioned mild thixotropy is good.
Background technique
As the improvement of people's living standards, good hygienic habit is increasingly valued by the people.Toothpaste is as people
Most common oral cavity cleaning and nursing product in daily life, both effectiveness and safety are also increasingly paid close attention to by people.Toothpaste is logical
Often containing grinding agent, moisturizer, foaming agent, thickener, preservative, flavoring agent and water etc., due to the hydrated silica of certain partial size
(silica) can remove the attachment and plaque of tooth very well, and therefore, traditional toothpaste mostly uses hydrated silica to make greatly
It is more although those skilled in the art had done many improvement on the formula of tooth paste product in recent years for its main grinding agent
Be to start in terms of whitening, mothproof and other effects property, grinding agent still uses hydrated silica, such as application No. is
The Chinese patent application of CN201510983752.9, entitled " a kind of whitening and protective toothpaste ", the content of hydrated silica are still
16%-18%；Since the hardness of hydrated silica is between the enamel and cementum of tooth, brush teeth year in year out, tooth surface layer
Enamel serious wear, to easily lead to the generation of odontopathy, and find, 2-6 years old children, brushed teeth every time all according to correlation study
The toothpaste of 1/8-1/4 can be swallowed, therefore, finds friction a kind of soft and that strong adsorption force, cleaning force are excellent and ingredient is edible
Agent substitutes used hard hydrated silica rubbing agent, is the trend of tooth paste product development.
In addition, being mostly used sodium carboxymethylcellulose, sodium alginate etc. in existing toothpaste system as thickener, this kind of thickening
The case where toothpaste that agent is worked it out is much more sticky, and the toothpaste of extrusion usually has hangover wire drawing, in the process brushed teeth, due to
Lotion of toothpaste is more sticky, and thixotroping speed is not fast enough after contacting tooth, often has lotion of toothpaste and goes out with the phenomenon that falling under foam
Existing, this not only results in certain waste, undoubtedly and existing formula system it is one big insufficient, therefore, research and develop a thixotropy
Good toothpaste and those skilled in the art is endeavoured to solve the problems, such as.
Summary of the invention
To solve the problems, such as present on, that the object of the present invention is to provide a kind of cleaning effects is excellent, to tooth enamel
Abrasion is few, and can increase the good toothpaste of the thixotropic mild thixotropy of product.
It is a further object of the present invention to provide a kind of preparation methods of toothpaste that above-mentioned mild thixotropy is good.
In order to achieve the above object, the toothpaste that mild thixotropy of the invention is good, is by moisturizer by weight percentage
15-50%, main rubbing agent 10-30%, rubbing agent 0-20%, thixotropic agent 0.5-3.0%, thickener 0.1-2.0%, foaming agent 1.0- are helped
10%, corrigent 5.0-15%, fragrance 0.1-3.0%, bacteriostatic agent 0.02-3.0% and balance deionized water are constituted；Wherein main rubbing agent
For the cellulose or microcrystalline cellulose porous granule of partial size 70-400um；Helping rubbing agent is calcium carbonate, calcium phosphate dibasic dihydrate, Portugal
One of grape Calciofon is a variety of；Thixotropic agent is that first xanthan gum is distributed in water, and adding partial size is the micro- of 0.1-20um
Crystalline cellulose porous granule, homogeneous is to keeping its fully dispersed, and then spray drying is formed, weight hundred of the xanthan gum in thixotropic agent
Divide than being 10-20%, weight percent of the microcrystalline cellulose porous granule in thixotropic agent is 80-90%.
The auspicious model Vivapur CS for stepping on Meier father and son company (abbreviation JRS) production of the preferred Germany of above-mentioned thixotropic agent
The three-dimensional stability agent of 032XV.
The auspicious model ViTACEL for stepping on Meier father and son company (abbreviation JRS) production of the preferred Germany of above-mentioned main rubbing agent
One of cellulose/microcrystalline cellulose porous granule of CS150, Vivapur 130FM is a variety of.Above-mentioned moisturizer is preferred
One of sorbierite, glycerol, propylene glycol or polyethylene glycol are a variety of.
In order to avoid children accidentally swallow toothpaste when brushing teeth, the preferred food level sodium carboxymethylcellulose of above-mentioned thickener, Huang
It is one or more in virgin rubber or sodium alginate.
One of above-mentioned foaming agent preferably sodium dodecyl sulfate, sodium lauroyl sarcosine are a variety of.
One of the preferred xylitol of above-mentioned corrigent, tri-chloro galactose type sugar, steviol glycoside are a variety of.
One of the preferred edible essence of above-mentioned fragrance, mint extract, menthol, bergamot berry extract are a variety of.
One of above-mentioned bacteriostatic agent optimization citric acid zinc, sodium benzoate are a variety of.
The present invention also provides a kind of preparation methods of toothpaste that above-mentioned mild thixotropy is good, and this method will be gone by formula ratio
Ionized water is first added in emulsion pot, and thixotropic agent, clearance-type homogeneous 3-5min are added in the case of stirring, and vacuumizing and defoaming is formed
A phase；Thickener is dispersed with moisturizer, adds in A phase, is stirred until homogeneous, sequentially add foaming agent, rubs agent and is helped
Rubbing agent is warming up to 80-85 DEG C, stirs, heat preservation 10min uniform to lotion, and vacuumizing and defoaming is slow under agitation to drop
Temperature sequentially adds corrigent, fragrance and bacteriostatic agent after temperature is lower than 40 DEG C, stirs evenly, discharges, obtain required toothpaste material
Body.
The good toothpaste of mild thixotropy of the invention has the advantages that compared with existing toothpaste
1, fine using cellulose or crystallite using the cellulose of greater particle size or microcrystalline cellulose particle as main grinding agent
The excellent flexibility tieing up the hatch frame of plain conduit and having, during brushing teeth, cellulose or microcrystalline cellulose squeeze tooth
Pressure and rubbing action, can remove the attachment and plaque of tooth very well, have very excellent absorption cleaning effect, simultaneously
The material softness of cellulose or microcrystalline cellulose is not easy damage tooth enamel, and safe to the human body has no toxic side effect.
2, using the three-dimensional stability agent obtained by the xanthan gum package lesser microcrystalline cellulose porous granule of partial size as touching
Become agent, so that xanthan gum is become three-dimensional stereopsis by electrical charge rejection using the microcrystalline cellulose on xanthan molecules chain node, this
Kind three-dimensional stereopsis is very easy to that branch swing occurs and declines the viscosity of toothpaste system under external force, to guarantee tooth
Cream has good thixotropy, in addition, the thixotropic agent of this special construction is containing surfactant, ionic ingredient and frosted
It is highly stable in the toothpaste system of class farinose material, the problem of guarantee system is not in bleed.
3, the raw material that formula uses all is edible ingredient, will not if accidentally swallow a small amount of toothpaste when brushing teeth
Generate any toxic side effect.
4, toothpaste of the invention, preparation process is simple, and obtained properties of product are stablized, and using effect is splendid, is a kind of value
The toothpaste that must be promoted the use of.
Specific embodiment
Below by specific embodiment, technical scheme is described further, but these embodiments are not used
In limiting the scope of the invention, under the premise of not departing from theory of the present invention, to the equivalent replacement of each component or each component
The adjustment of proportion, is within the scope of protection of the invention.
One, embodiment
Embodiment 1
1, it is formulated (by weight)
Glycerol 8.0%
Sorbierite 10.0%
VIVAPUR CS 032 XV 1.0%
Sodium carboxymethylcellulose 1.0%
VITACEL CS 150 F 15.0%
Calcium phosphate dibasic dihydrate 8.0%
Sodium lauroyl sarcosine 5.0%
Xylitol 5.0%
Steviol glycoside 0.3%
Edible essence 0.2%
Menthol 0.2%
Zinc citrate 0.8%
Deionized water is to 100%
2, it prepares
(1) raw material has been weighed by said ratio；
(2) deionized water is added in kettle, VIVAPUR CS 032XV, clearance-type homogeneous is added in the case of stirring
3-5min, vacuumizing and defoaming form A phase；
(3) sodium carboxymethylcellulose is added in glycerol and sorbierite, sodium carboxymethylcellulose is allowed to be well dispersed in glycerol
It in sorbierite, then is added slowly in A phase, stirs evenly；Sequentially add sodium lauroyl sarcosine, 150 F of VITACEL CS
And calcium phosphate dibasic dihydrate, it is warming up to 80-85 DEG C and stirs, heat preservation 10min uniform to lotion, vacuumizing and defoaming；
(4) slow cooling sequentially adds xylitol, stevioside after temperature is brought down below 40 DEG C in the case of stirring
Glycosides, edible essence, menthol, zinc citrate, stir evenly, and can discharge, and obtain required toothpaste sample.
Embodiment 2
1, it is formulated (by weight)
Glycerol 5.0%
Propylene glycol 5.0%
Sorbierite 10.0%
VIVAPUR CS 032 XV 1.0%
Sodium alginate 0.8%
VIVAPUR CS 130 FM 15.0%
Calcium phosphate dibasic dihydrate 5.0%
Calcium gluconate 3.0%
Sodium lauroyl sarcosine 5.0%
Xylitol 5.0%
Steviol glycoside 0.3%
Edible essence 0.2%
Menthol 0.2%
Mint extract 1.0%
Zinc citrate 0.8%
Deionized water is to 100%
2, it prepares
(1) raw material has been weighed by said ratio；
(2) deionized water is added in kettle, 032 XV of VIVAPUR CS, clearance-type homogeneous is added in the case where stirring
3-5min, vacuumizing and defoaming form A phase；
(3) sodium alginate is added in glycerol, propylene glycol and sorbierite, sodium alginate is allowed to be well dispersed in glycerol, the third two
It in pure and mild sorbierite, then is added slowly in A phase, stirs evenly；Sequentially add sodium lauroyl sarcosine, VIVAPUR CS 130
FM, calcium gluconate and calcium phosphate dibasic dihydrate, are warming up to 80-85 DEG C and stirring is uniform to lotion, keep the temperature 10min, vacuumize
Deaeration；
(4) slow cooling sequentially adds xylitol, stevioside after temperature is brought down below 40 DEG C in the case of stirring
Glycosides, edible essence, menthol, mint extract, zinc citrate, stir evenly, and can discharge, and obtain required toothpaste sample.
Embodiment 3
1, it is formulated
Glycerol 10.0%
Sorbierite 10.0%
VIVAPUR CS 032XV 1.5%
Sodium alginate 0.8%
VITACEL CS 150F 18.0%
Lauryl sodium sulfate 5.0%
Xylitol 5.0%
Steviol glycoside 0.3%
Edible essence 0.2%
Menthol 0.2%
Bergamot extract 1.0%
Zinc citrate 0.8%
Deionized water is to 100%
2, it prepares
(1) raw material has been weighed by said ratio；
(2) deionized water is added in kettle, 032 XV of VITACEL CS, clearance-type homogeneous is added in the case where stirring
3-5min, vacuumizing and defoaming form A phase；
(3) sodium alginate is added in glycerol and sorbierite, sodium alginate is allowed to be well dispersed in glycerol and sorbierite, then
It is added slowly in A phase, stirs evenly；Lauryl sodium sulfate, 150F are sequentially added, be warming up to 80-85 DEG C and is stirred to cream
Body is uniform, keeps the temperature 10min, vacuumizing and defoaming；
(4) slow cooling sequentially adds xylitol, stevioside after temperature is brought down below 40 DEG C in the case of stirring
Glycosides, edible essence, menthol, bergamot extract, zinc citrate, stir evenly, and can discharge, and obtain required toothpaste sample.
Two, sample stability detects
According to QB 8372-2008 standard, the obtained product of embodiment 1-3 is tested, indices are as follows:
| Project | Index | Embodiment 1 | Embodiment 2 | Embodiment 3 |
| Lotion | Uniformly, foreign | Meet | Meet | Meet |
| PH value | 5.5-10 | 7.9 | 7.5 | 7.1 |
| Stability | Lotion does not isolate liquid, and fragrance color is normal | Meet | Meet | Meet |
| Cross grit | Slide no marking | Meet | Meet | Meet |
| It is solvable free to measure not or not | 0.05-0.11/% | Meet | Meet | Meet |
As can be seen from the above table, the good toothpaste of mild thixotropy of the invention, every organoleptic indicator, defend physical and chemical index
Raw index complies fully with QB 8372-2008 standard, while the sample of embodiment 1,2,3 is also placed in -10 DEG C, 48 DEG C by us
In the environment of respectively store 48 hours, restore after taking-up to room temperature, find the uniform foreign of lotion, it is seen that its resistance to jelly, heat resistance
Also very good.
Three, using effect is tested
30 volunteers are selected, the sample made from embodiment 1-3 is tested, and toothpaste about 1g is squeezed out every time, when brushing teeth
The phenomenon that being dropped out without lotion of toothpaste appearance, and using comfortable.
Due to the porous granule of cellulose material, structure is corynebacterium, and fiber duct keeps complete, can deep enough teeth space
With tooth turning, the sample of embodiment 1,3 has superior cleaning capacity than the sample of embodiment 2 in terms of cleannes.
Claims (8)
1. a kind of mildly and with thixotropic toothpaste, which rubbed by moisturizer 15-50%, master by weight percentage
Liniment 10-30%, rubbing agent 0-20%, thixotropic agent 0.5-3.0%, thickener 0.1-2.0%, foaming agent 1.0-10%, corrigent are helped
5.0-15%, fragrance 0.1-3.0%, bacteriostatic agent 0.02-3.0% and balance deionized water are constituted；Wherein main rubbing agent is partial size 70-
The cellulose or microcrystalline cellulose porous granule of 400um；Helping rubbing agent is calcium carbonate, calcium phosphate dibasic dihydrate, calcium gluconate
One of or it is a variety of；Thixotropic agent is the three-dimensional of the auspicious model Vivapur CS 032XV for stepping on the production of Meier father and son company of Germany
Stabilizer；The preparation method of the toothpaste is first to be added to deionized water in emulsion pot by formula ratio, is added in the case of stirring
Thixotropic agent, clearance-type homogeneous 3-5min, vacuumizing and defoaming form A phase；Thickener is dispersed with moisturizer, adds in A phase, stirs
It mixes to uniform, sequentially adds foaming agent, main rubbing agent and help rubbing agent, be warming up to 80-85 DEG C, stir, heat preservation uniform to lotion
10min, vacuumizing and defoaming, slow cooling, sequentially adds corrigent, fragrance and suppression after temperature is lower than 40 DEG C under agitation
Microbial inoculum stirs evenly, and discharging obtains required toothpaste Material.
2. according to claim 1 mildly and with thixotropic toothpaste, it is characterised in that: the main rubbing agent is Germany
It is auspicious step on Meier father and son company (abbreviation JRS) production model ViTACEL CS150, Vivapur 130FM cellulose/it is micro-
One of crystalline cellulose porous granule is a variety of.
3. according to claim 1 or 2 mildly and with thixotropic toothpaste, it is characterised in that: the moisturizer is mountain
One of pears alcohol, glycerol, propylene glycol or polyethylene glycol are a variety of.
4. according to claim 3 mildly and with thixotropic toothpaste, it is characterised in that: the thickener is food-grade
It is one or more in sodium carboxymethylcellulose, xanthan gum or sodium alginate.
5. according to claim 4 mildly and with thixotropic toothpaste, it is characterised in that: the foaming agent is dodecane
One of base sodium sulphate, sodium lauroyl sarcosine are a variety of.
6. according to claim 5 mildly and with thixotropic toothpaste, it is characterised in that: the corrigent is xylose
One of alcohol, tri-chloro galactose type sugar, steviol glycoside are a variety of.
7. according to claim 6 mildly and with thixotropic toothpaste, it is characterised in that: the fragrance is peppermint extraction
One or both of object, bergamot berry extract.
8. according to claim 7 mildly and with thixotropic toothpaste, it is characterised in that: the bacteriostatic agent is citric acid
Zinc.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610315810.5A CN105902409B (en) | 2016-05-13 | 2016-05-13 | One kind is mild and has thixotropic toothpaste |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610315810.5A CN105902409B (en) | 2016-05-13 | 2016-05-13 | One kind is mild and has thixotropic toothpaste |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105902409A CN105902409A (en) | 2016-08-31 |
| CN105902409B true CN105902409B (en) | 2019-03-05 |
Family
ID=56749050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610315810.5A Active CN105902409B (en) | 2016-05-13 | 2016-05-13 | One kind is mild and has thixotropic toothpaste |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105902409B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106265103A (en) * | 2016-10-08 | 2017-01-04 | 肇庆市科捷人力资源服务有限公司 | The toothpaste of high-dispersion white carbon black without gel |
| CN110403851B (en) * | 2019-08-29 | 2022-03-08 | 无锡青禾小贝科技有限公司 | Anti-allergy toothpaste |
| SE543850C2 (en) * | 2019-12-11 | 2021-08-10 | Stora Enso Oyj | Method to produce a stable composition comprising hornificated nanocellulose particles, hornificated nanocellulose particle composition and its use |
| CN112274442A (en) * | 2020-09-22 | 2021-01-29 | 福建省梦娇兰日用化学品有限公司 | Children toothpaste containing calcium gluconate and preparation method thereof |
| TWI817111B (en) * | 2021-04-28 | 2023-10-01 | 歐萊德國際股份有限公司 | Compositions for oral cleaning |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1549704A (en) * | 2001-08-06 | 2004-11-24 | Stabilized oral suspension formulation | |
| CN101404892A (en) * | 2002-05-14 | 2009-04-08 | Fmc有限公司 | Microcrystalline cewllulose compositions |
| CN102429832A (en) * | 2011-11-28 | 2012-05-02 | 广州立白企业集团有限公司 | Novel abrasive compound and toothpaste comprising same |
| CN103599000A (en) * | 2013-11-20 | 2014-02-26 | 杭州皎洁口腔保健用品有限公司 | All-food-grade infant toothpaste and preparation method thereof |
| CN105012222A (en) * | 2014-04-28 | 2015-11-04 | 海南光宇生物科技有限公司 | Toothpaste composition by taking biologic cellulose nano powder as abrasive and preparation method |
-
2016
- 2016-05-13 CN CN201610315810.5A patent/CN105902409B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1549704A (en) * | 2001-08-06 | 2004-11-24 | Stabilized oral suspension formulation | |
| CN101404892A (en) * | 2002-05-14 | 2009-04-08 | Fmc有限公司 | Microcrystalline cewllulose compositions |
| CN102429832A (en) * | 2011-11-28 | 2012-05-02 | 广州立白企业集团有限公司 | Novel abrasive compound and toothpaste comprising same |
| CN103599000A (en) * | 2013-11-20 | 2014-02-26 | 杭州皎洁口腔保健用品有限公司 | All-food-grade infant toothpaste and preparation method thereof |
| CN105012222A (en) * | 2014-04-28 | 2015-11-04 | 海南光宇生物科技有限公司 | Toothpaste composition by taking biologic cellulose nano powder as abrasive and preparation method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105902409A (en) | 2016-08-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105902409B (en) | One kind is mild and has thixotropic toothpaste | |
| US20120189559A1 (en) | Carrageenan Products and Method for Their Production and Use | |
| CN105828782A (en) | Oral care compositions comprising calcium carbonate and a clay | |
| EP1139993A1 (en) | High water content dentifrice composition and method of making the same | |
| US6159446A (en) | High moisture toothpaste | |
| CN109431857B (en) | Toothpaste containing hyaluronic acid and preparation method thereof | |
| RU2705377C2 (en) | Compositions for oral care | |
| MX2008013710A (en) | Toothpaste. | |
| JP3977845B2 (en) | Toothpaste composition | |
| JP6125859B2 (en) | Composition for external use | |
| JP7447470B2 (en) | dentifrice composition | |
| JP5924049B2 (en) | Toothpaste composition | |
| CN108883315A (en) | Dentifrice composition | |
| BR112014002498B1 (en) | NON-WATERY ORAL TREATMENT COMPOSITION | |
| SE449563B (en) | TANDKREMKOMPOSITION | |
| CN114028273B (en) | Tooth cleaning composition | |
| JP6249642B2 (en) | Toothpaste composition and method for producing toothpaste composition | |
| JP4841146B2 (en) | Plaque staining composition | |
| JP3854715B2 (en) | Dentifrice composition | |
| KR102322170B1 (en) | Toothpaste composition | |
| JP6173735B2 (en) | Dentifrice composition | |
| JP7388126B2 (en) | Oral composition | |
| JP5552760B2 (en) | Toothpaste composition | |
| JP2017186332A (en) | Oral composition | |
| WO2016136719A1 (en) | Toothpaste composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |