CN105878851B - Pharmaceutical composition and preparation method thereof for treating syndrome of deficiency of both qi and blood - Google Patents
Pharmaceutical composition and preparation method thereof for treating syndrome of deficiency of both qi and blood Download PDFInfo
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- 210000004369 blood Anatomy 0.000 title claims abstract description 28
- 230000007812 deficiency Effects 0.000 title claims abstract description 21
- 208000011580 syndromic disease Diseases 0.000 title claims abstract description 20
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 17
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
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- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 claims abstract description 9
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 claims abstract description 9
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- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 9
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- 238000010438 heat treatment Methods 0.000 claims description 6
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- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 3
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/52—Juglandaceae (Walnut family)
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Abstract
Pharmaceutical composition and preparation method thereof for treating syndrome of deficiency of both qi and blood is related to syndrome of deficiency of both qi and blood treatment technology field.The effective component of pharmaceutical composition is made by 95-105g donkey-hide gelatin, 95-105g Radix Astragali, 35-50g fructus lycii, 35-60g arillus longan, 95-105g Chinese yam, 35-50g walnut kernel, 30-45g Semen sesami nigrum, 35-50g charred FRUCTUS CRATAEGI, 35-50g coloured malt, 25-40g flower bud of Japanese apricot, 25-40g dried orange peel and 290-305g maltose.Pharmaceutical composition of the present invention is according to obtained by the variation of human body the bottom of heart yang blood and qi actual situation, by immersion, decoction, concentration, receive the techniques such as cream, purification is process, it is while nourishing, also have the function of strengthening the spleen and stomach, avoid herbal paste and grow greasy thick and heavy, the phenomenon that hindering digestion, patient's reflection is good, significant in efficacy.Meanwhile preparation process is simple, without other additives, pollution-free, environmentally protective.
Description
Technical field
The present invention relates to syndrome of deficiency of both qi and blood treatment technology fields, are specifically related to a kind of for treating the medicine of syndrome of deficiency of both qi and blood
Compositions and preparation method thereof.
Background technique
Today's society, with the improvement of people's living standards, health care consciousness is gradually reinforced, traditional Chinese medicine is being controlled
Positive effect is not played in terms of disease, prevention and treatment of chronic diseases field, guarantee and enhancement people's health.Chinese medicine think " in healthy tendency deposits,
Heresy can not be done ", under the guidance of diagnosis and treatment based on an overall analysis of the illness and the patient's condition principle of reatment, by the medical treatment of herbal paste, body can be made to increase healthy tendency, improved disease-resistant
Ability checks exopathogen invasion, the deficient state of internal organs is enable to correct；Make equilibrium between yin and yang, qi and blood and tune, body function is gradually extensive
It is multiple, i.e., " yin and yang in equilibrium, life activities being normally maintained ", to reach salubrity, macrobiosis, diseases prevention, cure the disease, improve the purpose of Abwehrkraft des Koepers.Together
When it is good in taste due to herbal paste, it is convenient to take, therefore the compliance of patient also greatly improves over the course for the treatment of.
Summary of the invention
In order to solve the above-mentioned technical problem, it is more aobvious for syndrome of deficiency of both qi and blood curative effect that the purpose of the present invention is to provide one kind
Write, and blood-enrich, mental-tranquilization, strengthening the spleen and stomach pharmaceutical composition.
To achieve the goals above, the technical solution adopted in the present invention is as follows:
It is a kind of for treating the pharmaceutical composition of syndrome of deficiency of both qi and blood, effective component by following weight Chinese medicine material system
:
More preferably, for treating the pharmaceutical composition of syndrome of deficiency of both qi and blood, effective component by following weight Chinese medicine material
It is made:
Most preferably, for treating the pharmaceutical composition of syndrome of deficiency of both qi and blood, effective component by following weight Chinese medicine material
It is made:
Donkey-hide gelatin sweet in flavor and neutral in nature, tonifies the blood and arrest bleeding, nourishing Yin and moistening dryness；Radix Astragali is sweet in flavor and warm in property, strengthening spleen and middle warmer, invigorating qi for consolidating superficies, and the two is total
With, can QI invigorating and blood-nourishing, be altogether monarch drug in a prescription.Arillus longan nourishing the heart and spleen, replenishing qi and blood, tranquilizing the mind in side；Chinese yam supplementing qi and nourishing yin,
Tonifying spleen lung kidney；Fructus lycii is nourishing liver and kidney, benefiting essence-blood, improving eyesight；Walnut kernel kidney tonifying moistening lung, relax bowel and defecation；Semen sesami nigrum nourishing liver and kidney, strengthening the essence
Blood, ease constipation are dry；Five share altogether as ministerial drug, play the role of feeding essence and blood, nourishing liver and kidney.Hawthorn digestingization product, malt stomach strengthening and digestion promoting,
Flower bud of Japanese apricot dispersing stagnated hepatoqi, stomach function regulating, dried orange peel regulating qi-flowing for strengthening spleen, four medicines share to be allowed to mend for adjutant with many tonic essence and blood medicine compatibilities altogether
And it is oiliness, it mends without stagnant.Maltose is sweet, there is the function for adjusting benefit, the property of neutralization, and in the side of correcting for other drugs bad mouthfeel,
Make herbal paste convenient for taking, to make medicine.All medicines share play altogether blood-enrich, mental-tranquilization, strengthening the spleen and stomach function.It cures mainly qi-blood deficiency
Card shows themselves in that sallow complexion, four limbs burnout, shortness of breath lazyness speech, insomnia forgetfulness, loss of appetite etc..
The present invention is used to treat the pharmaceutical composition of syndrome of deficiency of both qi and blood, and a variety of dosage forms in pharmacy can be made, preferably make
At donkey-hide gelatin, donkey-hide gelatin the preparation method comprises the following steps:
1., medicinal material decoct and concentration:
Ten taste medicinal materials outside donkey-hide gelatin and maltose are removed, 10 times of weight waters is added to impregnate 30 minutes, are decocted three times, 1 hour every time,
Collecting decoction, filtration, filtrate is concentrated into the clear cream that relative density is 1.03-1.10, spare；
2., donkey-hide gelatin molten:
A certain amount of yellow rice wine is put into donkey-hide gelatin, did not had glue surface, is stirred, is infiltrated 24 hours, heating stirring is uniform to glue；
3., sugar refinery:
The distilled water for measuring sucrose weight 50% is put into container, is heated to boiling；Then sucrose is added, under stiring Xu
The tartaric acid edible of sucrose weight 0.1% is added in Xu, continues to be heated to liquid glucose into " wire drawing is hung flag, dropped into a bead " shape, maltosemalt sugar
Sugar；
4., receive cream:
In the clear cream 1. step is concentrated after be added maltose and molten glue, small fire heating receive cream to get.
12 taste donkey-hide gelatin prepared by the present invention is a kind of prescription with nutritious tonifying and prophylactic treatment comprehensive function,
Prescription is under the theoretical direction of differentiation of tcm and Chinese medicine organic conception, according to the variation of human body the bottom of heart yang blood and qi actual situation
, selected Chinese medicine meets the regulation of 2015 editions Chinese Pharmacopoeias, by immersion, decoction, concentration, receives the techniques such as cream, essence
The phenomenon that system is process, and while nourishing, also have the function of strengthening the spleen and stomach, and it is greasy thick and heavy to avoid herbal paste taste, hinders digestion,
Patient's reflection is good, significant in efficacy.Meanwhile preparation process is simple, without other additives, pollution-free, environmentally protective.
Specific embodiment
The present invention is further illustrated with reference to embodiments.
Embodiment 1
One, 12 taste donkey-hide gelatin, effective component are made by the Chinese medicine material of following weight:
Two, steps are as follows for the preparation method of 12 taste donkey-hide gelatins:
1., medicinal material decoct and concentration:
Ten taste medicinal materials outside donkey-hide gelatin and maltose are removed, 10 times of weight waters is added to impregnate 30 minutes, are decocted three times, 1 hour every time,
Collecting decoction, filtration, filtrate is concentrated into the clear cream that relative density is 1.03-1.10 (20 DEG C), spare.
2., donkey-hide gelatin molten:
A certain amount of yellow rice wine is put into donkey-hide gelatin, did not had glue surface, is stirred, is infiltrated 24 hours, heating stirring is uniform to glue.
3., sugar refinery:
The distilled water for measuring sucrose weight 50% is put into container, is heated to boiling；Then sucrose is added, under stiring Xu
The tartaric acid edible of sucrose weight 0.1% is added in Xu, continues to be heated to liquid glucose into " wire drawing is hung flag, dropped into a bead " shape, maltosemalt sugar
Sugar.
4., receive cream:
The glue of maltose and molten is added in the clear cream 1. step is concentrated after, small fire heating receives cream, finished product is made
1000g to get.
Three, the curative effect for treating syndrome of deficiency of both qi and blood compares
1. general information:
Choose syndrome of deficiency of both qi and blood patient 600 that the second affiliated hospital, Anhui University of Chinese Medecine accepts for medical treatment.Selected patient uses
Random digits table is divided into complex prescription glue mucilage group and 12 taste donkey-hide gelatin groups, every group each 300, two groups of patients the state of an illness, gender,
Age and the course of disease etc. are comparable.
2. treatment method:
Treatment group is treated using 12 taste donkey-hide gelatins；Control group uses complex prescription glue mucilage (Shandong Donga donkey-hide gelatin share
Co., Ltd, 20ml*12 branch/box) treatment.
Treatment group: boiled water is taken after mixing it with water, and daily 2 times, every time a soupspoon (about 25g), two weeks as a treatment course, is used in conjunction four
The course for the treatment of.
Control group: daily 3 times, one time one, two weeks are as a treatment course, and four courses for the treatment of are used in conjunction.
3. criterion of therapeutical effect:
Anaemia evaluation of clinical curative effect is carried out according to " diagnosis of hematological diseases and criterion of therapeutical effect ":
Cure: clinical symptoms completely disappear, and Hb (hemoglobin) amount restores normal, and keeps normally up to 3 months or more.
Effective: clinical symptoms are clearly better, and Hb (hemoglobin) amount significantly increases.
Invalid: clinical symptoms are unchanged.
4. efficacy evaluation result:
| Group | Case load | Cure rate (number of cases) | Improvement rate (number of cases) | Not more rate (number of cases) | Total effective rate (number of cases) |
| Treatment group | 300 | 22% (66) | 69% (207)* | 16% (48) | 91% (273)* |
| Control group | 300 | 16% (48) | 55% (165) | 33% (99) | 71% (213) |
Note: total effective rate compared with the control group,*P < 0.05
As it can be seen that compared with the control group, the effective percentage and total effective rate for the treatment of group are above control group from upper table, treatment
The curative effect of group is more significant.
Embodiment 2
It is a kind of for treating the pharmaceutical composition of syndrome of deficiency of both qi and blood, effective component by following weight Chinese medicine material system
:
Embodiment 3
It is a kind of for treating the pharmaceutical composition of syndrome of deficiency of both qi and blood, effective component by following weight Chinese medicine material system
:
Embodiment 4
It is a kind of for treating the pharmaceutical composition of syndrome of deficiency of both qi and blood, effective component by following weight Chinese medicine material system
:
Embodiment 5
It is a kind of for treating the pharmaceutical composition of syndrome of deficiency of both qi and blood, effective component by following weight Chinese medicine material system
:
Claims (3)
1. a kind of for treating the pharmaceutical composition of syndrome of deficiency of both qi and blood, it is characterised in that:
Its effective component is made by the Chinese medicine material of following weight:
Preparation method step are as follows:
1., medicinal material decoct and concentration:
Ten taste medicinal materials outside donkey-hide gelatin and maltose are removed, 10 times of weight waters is added to impregnate 30 minutes, decocts three times, 1 hour every time, merges
Decocting liquid, filtration, filtrate is concentrated into the clear cream that relative density is 1.03-1.10, spare；
2., donkey-hide gelatin molten:
A certain amount of yellow rice wine is put into donkey-hide gelatin, did not had glue surface, is stirred, is infiltrated 24 hours, heating stirring is uniform to glue；
3., sugar refinery:
The distilled water for measuring sucrose weight 50% is put into container, is heated to boiling；Then sucrose is added, adds slowly under stiring
The tartaric acid edible for entering sucrose weight 0.1%, continues to be heated to liquid glucose into " wire drawing is hung flag, dropped into a bead " shape, maltose；
4., receive cream:
In the clear cream 1. step is concentrated after be added maltose and molten glue, small fire heating receive cream to get.
2. as described in claim 1 for treating the pharmaceutical composition of syndrome of deficiency of both qi and blood, which is characterized in that its effective component by
The Chinese medicine material of following weight is made:
3. as claimed in claim 2 for treating the pharmaceutical composition of syndrome of deficiency of both qi and blood, which is characterized in that its effective component by
The Chinese medicine material of following weight is made:
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| CN112616984A (en) * | 2020-12-15 | 2021-04-09 | 盛秀群 | Donkey-hide gelatin maltose capable of tonifying qi, enriching blood, maintaining beauty and keeping young |
Citations (4)
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|---|---|---|---|---|
| CN102319410A (en) * | 2011-09-13 | 2012-01-18 | 成美娜 | Vital energy invigorating and blood nourishing traditional Chinese medicine composition, and preparation method thereof |
| CN103751518A (en) * | 2014-01-14 | 2014-04-30 | 安徽九方制药有限公司 | Oral liquid for tonifying Qi and replenishing blood and preparation method thereof |
| CN103751415A (en) * | 2013-12-31 | 2014-04-30 | 山东东阿阿胶股份有限公司 | Traditional Chinese medicinal composition and preparation method thereof |
| CN104666868A (en) * | 2015-01-07 | 2015-06-03 | 江怀 | Medicine for treating yin diseases caused by deficiency syndrome |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102319410A (en) * | 2011-09-13 | 2012-01-18 | 成美娜 | Vital energy invigorating and blood nourishing traditional Chinese medicine composition, and preparation method thereof |
| CN103751415A (en) * | 2013-12-31 | 2014-04-30 | 山东东阿阿胶股份有限公司 | Traditional Chinese medicinal composition and preparation method thereof |
| CN103751518A (en) * | 2014-01-14 | 2014-04-30 | 安徽九方制药有限公司 | Oral liquid for tonifying Qi and replenishing blood and preparation method thereof |
| CN104666868A (en) * | 2015-01-07 | 2015-06-03 | 江怀 | Medicine for treating yin diseases caused by deficiency syndrome |
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