CN105878555A - Traditional Chinese medicine composition for treating leucoderma - Google Patents

Traditional Chinese medicine composition for treating leucoderma Download PDF

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CN105878555A
CN105878555A CN201610468558.1A CN201610468558A CN105878555A CN 105878555 A CN105878555 A CN 105878555A CN 201610468558 A CN201610468558 A CN 201610468558A CN 105878555 A CN105878555 A CN 105878555A
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parts
radix
chinese medicine
herba
medicine composition
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丁常燕
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
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    • A61K36/74—Rubiaceae (Madder family)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia

Abstract

The invention discloses a traditional Chinese medicine composition for treating leucoderma. The traditional Chinese medicine composition comprises, by weight, 10-30 parts of herba ecliptae, 10-20 parts of ossa sepiae, 10-20 parts of radix lithospermi, 5-15 parts of radix angelicae dahuricae, 10-20 parts of radix codonopsis, 10-20 parts of oldenlandia diffusa, 10-20 parts of tetrapanax papyriferus, 5-15 parts of saposhnikovia divaricata, 10-20 parts of lonicera japonica, 10-20 parts of cotton root, 10-20 parts of ramulus mori, 5-15 parts of cortex dictamni, 10-20 parts of tephroseris kirilowii, 10-20 parts of Carduus crispus L., 5-15 parts of Caesalpinia sappan L., 10-20 parts of Amaranthus spinosus L., 10-20 parts of berchemia lineata, 5-15 parts of radix zanthoxyli, 10-20 parts of radix sophorae flavescentis, 10-20 parts of Akebia trifoliata Koidz, 10-20 parts of cortex mori radicis, 5-15 parts of lumbricus, 10-20 parts of radix rehmanniae praeparata and 5-15 parts of radix glycyrrhizae. The traditional Chinese medicine composition has effects of nourishing the liver and tonifying the kidney, promoting qi and blood circulation, dispelling wind and eliminating evil and clearing and activating the channels and collaterals and is evident in curative effect on the leucoderma and reliable in effect.

Description

One treats leukodermic Chinese medicine composition
Technical field
The present invention relates to the medicinal preparation not determining structure of a kind of traditional herbal medicines, especially one and treat leukodermic Chinese medicine composition.
Background technology
Vitiligo is a kind of common posteriority limit office's property or general property skin pigment depigmentation disease.The each position of whole body can occur, and is common in the finger back of the body, wrist, forearm, face, neck and surrounding genital etc..Skin lesion is depigmentation speckle, is often milky, it is possible to for lightpink, smooth surface is without erythra.White macula boundary understands, edge pigment compared with normal skin increases, and in white macula, hair is normal or bleaches.Pathological changes is apt to occur in is irradiated and damage by friction position by sunlight, and how symmetrical disease damage is.White macula the most often press nerve segment distribution and in zonation.In addition to skin lesion, inside lip, labia, glans penis and foreskin, mucosa is the most often got involved.Clinical treatment vitiligo is most commonly that the painless melanocyte of GX-B cultivates therapy now, and little area skin lesion therapeutic effect is good, but easily recurs, and spends height.
The traditional Chinese medical science is thought, vitiligo is to be won in skin by ailment said due to cold or exposure, causes cold qi-blood disharmony, yellowish pink neglect change and bleaches shape class freckles, pain of not itching.The primary disease cause of disease is complex, inside has seven emotions unsuccessful, has outward ailment said due to cold or exposure to take advantage of a weak point in opponent's defence and invade or injury from falling down all causes QI and blood indisposed, and moistening of congestion resistance network skin mistake is foster, leads to skin pigment depigmentation and existing white macula.
According to theory of Chinese medical science, for leukodermic pathogeny, with evil removing of dispeling the wind, regulation QI and blood as the rule for the treatment of, carry out dialectical composition of prescription, to reach the purpose for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
Prior art uses melanocyte cultivate therapy for treating vitiligo to exist and easily recur, spend high deficiency to overcome, the present invention provide a kind of prepare conveniently, medicine source is wide, evident in efficacy, reliable effect, the leukodermic Chinese medicine composition for the treatment of that has no side effect.
nullThe technical solution adopted for the present invention to solve the technical problems is: one treats leukodermic Chinese medicine composition，It is characterized in that: its raw material of Chinese medicine and weight be: Herba Ecliptae 10-30 part，Endoconcha Sepiae 10-20 part，Radix Arnebiae (Radix Lithospermi) 10-20 part，Radix Angelicae Dahuricae 5-15 part，Radix Codonopsis 10-20 part，Herba Hedyotidis Diffusae 10-20 part，Medulla Tetrapanacis 10-20 part，Radix Saposhnikoviae 5-15 part，Flos Lonicerae 10-20 part，Radix Gossypii 10-20 part，Ramulus Mori 10-20 part，Cortex Dictamni 5-15 part，Herba Senecionis Kirilowi 10-20 part，Herba Cardui Crispi 10-20 part，Lignum Sappan 5-15 part，Amaranthus mangostanus L. 10-20 part，Radix berchemiae lineatae 10-20 part，Radix Zanthoxyli 5-15 part，Radix Sophorae Flavescentis 10-20 part，Fructus Akebiae 10-20 part，Cortex Mori 10-20 part，Pheretima 5-15 part，Radix Rehmanniae Preparata 10-20 part，Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: one treats leukodermic Chinese medicine composition, it is characterized in that: its raw material of Chinese medicine and weight be: Herba Ecliptae 20 parts, Endoconcha Sepiae 15 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, the Radix Angelicae Dahuricae 10 parts, Radix Codonopsis 15 parts, Herba Hedyotidis Diffusae 15 parts, Medulla Tetrapanacis 15 parts, Radix Saposhnikoviae 10 parts, Flos Lonicerae 15 parts, Radix Gossypii 15 parts, Ramulus Mori 15 parts, Cortex Dictamni 10 parts, Herba Senecionis Kirilowi 15 parts, Herba Cardui Crispi 15 parts, Lignum Sappan 10 parts, Amaranthus mangostanus L. 15 parts, Radix berchemiae lineatae 15 parts, Radix Zanthoxyli 10 parts, Radix Sophorae Flavescentis 15 parts, Fructus Akebiae 15 parts, Cortex Mori 15 parts, Pheretima 10 parts, Radix Rehmanniae Preparata 15 parts, 10 parts of Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: Herba Ecliptae has effect of liver-nourishing kidney-boosting, cooling blood for hemostasis；Endoconcha Sepiae has astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, relieving gastric hyperacidity to alleviate stomachache, effect of removing dampness sore；Radix Arnebiae (Radix Lithospermi) has clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, effect of removing toxic substances rash；The Radix Angelicae Dahuricae has relieving exterior syndrome and dispelling cold, expelling pathogenic wind and restoring the functions of orifices in face, promoting blood circulation and stopping pain, dampness leukorrhagia stopping, effect of detumescence and apocenosis；Radix Codonopsis has effect of invigorating the spleen and replenishing QI, strengthening spleen and tonifying lung；Herba Hedyotidis Diffusae has effect of heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain；Medulla Tetrapanacis has clearing away heat and promoting diuresis, effect of ventilation stimulating milk secretion；Effect that Radix Saposhnikoviae has expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion are jerked surely；Flos Lonicerae has effect of heat-clearing and toxic substances removing, wind-heat dissipating；Radix Gossypii has qi-restoratives, relievings asthma, effect of regulating menstruation；Ramulus Mori has wind-damp dispelling、The effect in profit joint；Cortex Dictamni has heat clearing and damp drying, the effect of removing toxic substances of dispeling the wind；Herba Senecionis Kirilowi has effect of heat-clearing and toxic substances removing, inducing diuresis to remove edema, parasite killing；Herba Cardui Crispi have dispel the wind, clearing away heat-damp and promoting diuresis, cooling blood for hemostasis, effect of promoting blood circulation and detumescence；Lignum Sappan has effect of blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain；Amaranthus mangostanus L. has effect of cooling blood for hemostasis, eliminating damp-heat, removing toxicity for eliminating carbuncles；Radix berchemiae lineatae has effect of subduing swelling and detoxicating, hemostatic analgesia, expelling wind and removing dampness；Radix Zanthoxyli has effect of expelling wind and removing dampness, promoting blood circulation and detumescence；Radix Sophorae Flavescentis has effect of heat clearing and damp drying, wind dispelling insecticide；Fructus Akebiae has liver-smoothing, qi-regulating, promoting blood circulation and stopping pain, effect of relieving restlessness diuresis；Cortex Mori has effect of eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema；Pheretima has clearing heat for calming endogenous wind, lung-clearing asthma-relieving, inducing diuresis for treating stranguria syndrome, effect of current meridians；Radix Rehmanniae Preparata has effect of yin nourishing of enriching blood, life essence-filling, marrow-benefitting；Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.Drug component in the present composition, through dialectical compatibility, complements each other using, and has synergism, plays liver-nourishing kidney-boosting, promoting flow of QI and blood, evil removing of dispeling the wind, effect of dredge the meridian passage altogether, vitiligo reaches the purpose for the treatment of both the principal and secondary aspects of a disease.
The component of the present composition all uses natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, low cost.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug use the use that is decocted in water for oral dose.Verifying by clinic application, it is evident in efficacy, reliable effect, mild in medicine property and, toxic and side effects does not occurs, total effective rate 85%, cure rate reaches 52.5%.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
One treats leukodermic Chinese medicine composition, and its raw material of Chinese medicine and weight proportion be: Herba Ecliptae 20g, Endoconcha Sepiae 15g, Radix Arnebiae (Radix Lithospermi) 15g, Radix Angelicae Dahuricae 10g, Radix Codonopsis 15g, Herba Hedyotidis Diffusae 15g, Medulla Tetrapanacis 15g, Radix Saposhnikoviae 10g, Flos Lonicerae 15g, Radix Gossypii 15g, Ramulus Mori 15g, Cortex Dictamni 10g, Herba Senecionis Kirilowi 15g, Herba Cardui Crispi 15g, Lignum Sappan 10g, Amaranthus mangostanus L. 15g, Radix berchemiae lineatae 15g, Radix Zanthoxyli 10g, Radix Sophorae Flavescentis 15g, Fructus Akebiae 15g, Cortex Mori 15g, Pheretima 10g, Radix Rehmanniae Preparata 15g, Radix Glycyrrhizae 10g.
Embodiment 2
One treats leukodermic Chinese medicine composition, and its raw material of Chinese medicine and weight proportion be: lotus grass 10g, Endoconcha Sepiae 20g, Radix Arnebiae (Radix Lithospermi) 10g, Radix Angelicae Dahuricae 15g, Radix Codonopsis 10g, Herba Hedyotidis Diffusae 20g, Medulla Tetrapanacis 10g, Radix Saposhnikoviae 15g, Flos Lonicerae 10g, Radix Gossypii 20g, Ramulus Mori 10g, Cortex Dictamni 15g, Herba Senecionis Kirilowi 10g, Herba Cardui Crispi 20g, Lignum Sappan 5g, Amaranthus mangostanus L. 20g, Radix berchemiae lineatae 10g, Radix Zanthoxyli 15g, Radix Sophorae Flavescentis 10g, Fructus Akebiae 20g, Cortex Mori 10g, Pheretima 15g, Radix Rehmanniae Preparata 10g, Radix Glycyrrhizae 15g.
Embodiment 3
One treats leukodermic Chinese medicine composition, and its raw material of Chinese medicine and weight proportion be: lotus grass 30g, Endoconcha Sepiae 10g, Radix Arnebiae (Radix Lithospermi) 20g, Radix Angelicae Dahuricae 5g, Radix Codonopsis 20g, Herba Hedyotidis Diffusae 10g, Medulla Tetrapanacis 20g, Radix Saposhnikoviae 5g, Flos Lonicerae 20g, Radix Gossypii 10g, Ramulus Mori 20g, Cortex Dictamni 5g, Herba Senecionis Kirilowi 20g, Herba Cardui Crispi 10g, Lignum Sappan 15g, Amaranthus mangostanus L. 10g, Radix berchemiae lineatae 20g, Radix Zanthoxyli 5g, Radix Sophorae Flavescentis 20g, Fructus Akebiae 10g, Cortex Mori 20g, Pheretima 5g, Radix Rehmanniae Preparata 20g, Radix Glycyrrhizae 5g.
Embodiment 4
One treats leukodermic Chinese medicine composition, and its raw material of Chinese medicine and weight proportion be: lotus grass 15g, Endoconcha Sepiae 18g, Radix Arnebiae (Radix Lithospermi) 12g, Radix Angelicae Dahuricae 13g, Radix Codonopsis 12g, Herba Hedyotidis Diffusae 18g, Medulla Tetrapanacis 12g, Radix Saposhnikoviae 13g, Flos Lonicerae 12g, Radix Gossypii 18g, Ramulus Mori 12g, Cortex Dictamni 13g, Herba Senecionis Kirilowi 12g, Herba Cardui Crispi 18g, Lignum Sappan 8g, Amaranthus mangostanus L. 18g, Radix berchemiae lineatae 12g, Radix Zanthoxyli 13g, Radix Sophorae Flavescentis 12g, Fructus Akebiae 18g, Cortex Mori 12g, Pheretima 13g, Radix Rehmanniae Preparata 12g, Radix Glycyrrhizae 13g.
Embodiment 5
One treats leukodermic Chinese medicine composition, and its raw material of Chinese medicine and weight proportion be: lotus grass 25g, Endoconcha Sepiae 12g, Radix Arnebiae (Radix Lithospermi) 18g, Radix Angelicae Dahuricae 8g, Radix Codonopsis 18g, Herba Hedyotidis Diffusae 12g, Medulla Tetrapanacis 18g, Radix Saposhnikoviae 8g, Flos Lonicerae 18g, Radix Gossypii 12g, Ramulus Mori 18g, Cortex Dictamni 8g, Herba Senecionis Kirilowi 18g, Herba Cardui Crispi 12g, Lignum Sappan 13g, Amaranthus mangostanus L. 12g, Radix berchemiae lineatae 18g, Radix Zanthoxyli 8g, Radix Sophorae Flavescentis 18g, Fructus Akebiae 12g, Cortex Mori 18g, Pheretima 8g, Radix Rehmanniae Preparata 18g, Radix Glycyrrhizae 8g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: put in container by the raw material of Chinese medicine of prescription, adds cold water and covers powder, soak 15～20 minutes, added water no powder about 8 centimetres, carries out decocting for the first time, at a simmer before use intense fire to decoct, with slow fire boiling 20～30 minutes after boiling；Second time decocts, and added water no powder about 6 centimetres, decocts 15～20 minutes after water boiling.Twice decoction is removed slag extracting juice, merges.
The present invention treats leukodermic Chinese medicine composition with the one given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: Chinese medicine composition of the present invention is applied to clinical observation case 40 example, the maleest 23 examples, female 17 example, age 20～60 years old.
Two, diagnostic criteria:
1, skin lesion color bleaches, or speckle or point, and shape differs, without sufferings；
2, can occur at health everywhere, common with extremity, head；
3, feelings will internal injury it is more common in young；
4, tissue pathology checking shows that epidermis substantially lacks melanocyte and melanin granule, and basal layer is often complete lack of the melanocyte that dopa stain is positive.
Three, usage and dosage: during clinical practice, one day potion, decocting twice extracting juice about 400ml, point early, late twice warm is taken, and within ten days, is a course for the treatment of.
Four, criterion of therapeutical effect:
1, curing: skin lesion disappears, the colour of skin recovers normal；
2, take a turn for the better: more than 30% skin lesion is normal color of the leather, or in decolouring speckle, coloured vegetarian refreshments generates；
3, do not heal: skin lesion color is without significant change.
Five, therapeutic effect: in this clinical observation case, take medicine 5-15 the course for the treatment of, cure 21 examples, take a turn for the better 13 examples, the most 6 examples.Toxic and side effects is there is not during treatment.
Six, model case:
Case 1: Wang, man, 22 years old.There is leukasmus on rear side of arm, accompany fatigue and weakness, dysphoria with feverish sensation in the chest palms and soles.Red tongue, tongue is few, deep-thready pulse.After 5 courses for the treatment of of medicament taking prepared by the Chinese medicine composition of the present invention, conscious fatigue and weakness, dysphoria with feverish sensation in the chest palms and soles symptom alleviate, and white spot area reduces；Continuing to take 4 courses for the treatment of, white macula is wholly absent, and skin recovers normal skin tone, cures.
Case 2: grandson, female, 37 years old, there is suddenly large area white macula, painless gargalesthesia in abdominal part, repeatedly treats, recurrent exerbation in 1 year, generally had depression of QI and the situation of vexed uneasiness.Examine and see: light red tongue, white and thin fur, moderate pulse.After 6 courses for the treatment of of medicament taking prepared by the Chinese medicine composition of the present invention, depression of QI and vexed uneasy transference cure, abdominal part white macula is wholly absent；Consolidate and take 5 courses for the treatment of, cure.

Claims (2)

  1. null1. treat leukodermic Chinese medicine composition for one kind，It is characterized in that: its raw material of Chinese medicine and weight be: Herba Ecliptae 10-30 part，Endoconcha Sepiae 10-20 part，Radix Arnebiae (Radix Lithospermi) 10-20 part，Radix Angelicae Dahuricae 5-15 part，Radix Codonopsis 10-20 part，Herba Hedyotidis Diffusae 10-20 part，Medulla Tetrapanacis 10-20 part，Radix Saposhnikoviae 5-15 part，Flos Lonicerae 10-20 part，Radix Gossypii 10-20 part，Ramulus Mori 10-20 part，Cortex Dictamni 5-15 part，Herba Senecionis Kirilowi 10-20 part，Herba Cardui Crispi 10-20 part，Lignum Sappan 5-15 part，Amaranthus mangostanus L. 10-20 part，Radix berchemiae lineatae 10-20 part，Radix Zanthoxyli 5-15 part，Radix Sophorae Flavescentis 10-20 part，Fructus Akebiae 10-20 part，Cortex Mori 10-20 part，Pheretima 5-15 part，Radix Rehmanniae Preparata 10-20 part，Radix Glycyrrhizae 5-15 part.
  2. One the most according to claim 1 treats leukodermic Chinese medicine composition, it is characterized in that: its raw material of Chinese medicine and weight be: Herba Ecliptae 20 parts, Endoconcha Sepiae 15 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, the Radix Angelicae Dahuricae 10 parts, Radix Codonopsis 15 parts, Herba Hedyotidis Diffusae 15 parts, Medulla Tetrapanacis 15 parts, Radix Saposhnikoviae 10 parts, Flos Lonicerae 15 parts, Radix Gossypii 15 parts, Ramulus Mori 15 parts, Cortex Dictamni 10 parts, Herba Senecionis Kirilowi 15 parts, Herba Cardui Crispi 15 parts, Lignum Sappan 10 parts, Amaranthus mangostanus L. 15 parts, Radix berchemiae lineatae 15 parts, Radix Zanthoxyli 10 parts, Radix Sophorae Flavescentis 15 parts, Fructus Akebiae 15 parts, Cortex Mori 15 parts, Pheretima 10 parts, Radix Rehmanniae Preparata 15 parts, 10 parts of Radix Glycyrrhizae.
CN201610468558.1A 2016-06-25 2016-06-25 Traditional Chinese medicine composition for treating leucoderma Pending CN105878555A (en)

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