CN105832906A

CN105832906A - Drug for treating pimples

Info

Publication number: CN105832906A
Application number: CN201610287704.0A
Authority: CN
Inventors: 包莉丽
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-05-04
Filing date: 2016-05-04
Publication date: 2016-08-10

Abstract

The invention relates to a drug for treating pimples .The drug is prepared from, by weight, 9 parts of Cassia javanica L .var .indo-chinensis Gagnep., 15 parts of all-grass of Drooping carpesium, 10 parts of roots of Slant Stephania, 9 parts of a barbed shullcap herb, 9 parts of roots and rhizomes of Javan Meadowrue, 12 parts of rhizomes of Kamchatka Bugbane, 15 parts of a Spreading Hedyotis herb, 18 parts of a herb of Whiteflower Violet, 6 parts of roots of Wintersweet, 6 parts of a repent pellionia herb and 6 parts of licorice roots .During application, the Cassia javanica L .var .indo-chinensis Gagnep clears away heat and toxic materials, regulates vital energy and lubricates the intestines; the all-grass of Drooping carpesium clears away heat and toxic materials and relieves swelling and pain; the roots of Slant Stephania clear away heat and toxic materials, cool blood and remove ecchymosis; the barbed shullcap herb relieves exterior syndrome by dispersion, clears away heat and promotes diuresis; the roots and rhizomes of Javan Meadowrue clear away heat and toxic materials and eliminate dampness; the rhizomes of Kamchatka Bugbane relieve exterior syndrome, promote eruption, clear away heat and toxic materials and clear yang fails to ascend; the Spreading Hedyotis herb clears away heat and toxic materials, induces diuresis to reduce edema, invigorates blood circulation and alleviates pain; the herb of Whiteflower Violet clears away heat and toxic materials and cools blood for detumescence; the roots of Wintersweet dispel the wind, regulate vital energy, invigorate blood circulation and clear away toxic materials; the repent pellionia herb clears away heat and promotes dampness; the licorice roots clear away heat and toxic materials, protect the stomach, regulate the middle-energizer and regulate medicinal nature .The medicinal materials are applied in a combined mode to play the effects of clearing away heat, removing dampness, relaxing bowels, harmonizing ying, reducing phlegm and resolving masses .Clinical experiments prove that the drug can safely and effectively treat the pimples.

Description

A kind of medicine for treating pimples

Technical field

The present invention relates to a kind of Chinese medicine, be specifically related to a kind of medicine for treating pimples.

Background technology

Primary disease belongs to " acne " in modern medicine, is a kind of pilosebaceous acute or chronic inflammation.There are blackhead, mound The multiple infringements such as rash, pustule, tuberosity, abscess, cyst and cicatrix, are apt to occur in face and chest and back.Common are acne vulgaris and Acne conglobata.Primary disease also known as acne of youth, the multiple adolescence men and women being born in 15-30 year, be often accompanied by seborrhea.The course of disease is slow Property, time light time weight, women Chang Yue is premenstrual in periodically increasing the weight of.Primary disease has self limiting.After most patient's adolescence gradually Alleviate, most spontaneous recovery or alleviate.

The traditional Chinese medical science: rosacea caused by lung-wind, acne vulgaris, whelk, the cause of disease of primary disease is that lung qi is unclear, outward by wind heat；Or be eating and drinking without temperance, mistake Food delicious food savoury, upward steaming of stomach-heat；Also can be menoxenia, stasis of blood stagnation-derived fever etc..

Clinical manifestation

Skin lesion takes place mostly in face, it is possible to occurs at thoracic dorsal top and shoulder, the most also betides other positions, socket of the eye week skin Never involving, during beginning, patient almost has blackhead and seborrhea adiposa to go out, and the most often has pimple, tuberosity, pustule, pus Swollen, sinus tract or cicatrix, the size depth of various infringements, often based on wherein 1 kinds of infringements, the course of disease is long, how without conscious Symptom, time as obvious in inflammation, then can cause pain and touch pain, and weight time light during symptom, after adolescence, most patient all can be natural Recovery from illness or symptom alleviate, and can be divided into following several types according to the main performance of skin lesion clinically:

1. stictacne blackhead is the major determinant of acne, is to fill in the cheese shape semisolid at pilosebaceous orifices, is exposed at The outer end blackout of follicular orifice, as added extrusion, it is seen that head is black and the body translucent fat bolt discharge that is yellow-white.

2. acne papulosa skin lesion is based on the little pimple of inflammatory, and Semen setariae to pea-sized hard little pimple, in light red Color can have the seborrheic plug of the non-blackening of a blackhead or top to peony, pimple central authorities.

3. pustular acne shows as main with abscess, pustule be grain to Semen phaseoli radiati size, for pityriasis rubra pustule and pimple top End forms pustule, broken rear pus relatively thickness, leaves over shallow cicatrix the most afterwards.

4. acne nodosum is when inflamed sites is deeper, and pustular acne can develop into the tuberosity of wall thickness, and size is not Deng, in pale red or aubergine, some positions are relatively deep, have a notable protuberance and at hemispherical or cone, they can be deposited for a long time Or gradually absorb, some suppuration diabrosis form significant cicatrix.

5. acne atrophica pimple or pustular lesions destroy body of gland, cause pit shape atrophic scar, the pustule of diabrosis Or pimple and the pustule naturally absorbed all can cause fibroid to become and atrophy.

6. acne cystica forms the sebaceous cyst differed in size, Chang Jifa suppurative infection, normal elution band blood after ulceration Gelatin pus, and inflammation does not weighs, before forming sinus tract and scar later.

7. acne conglobata is to damage the most serious one, skin lesion multiform, has a lot of acne, pimple, pustule, abscess, Cyst and sinus tract, cicatrix, keloid cluster occurs.

8. malignant disease acne lesions is Semen setariae to the green lake of Semen Viciae fabae size or aubergine pimple, pustule or tuberosity, softly Soft, and containing pus and blood, they are not healed, and small cicatrix is left in recovery from illness later, does not the most feel pain, and infiltration is the most very Few, this kind of is more common in weakly patient.

The diagnosis of this disease relies primarily on lab testing

1. erythra, generally there is obvious lectin from hemolymph and changes in abnormal results erythra patient.Some have heredity or crucial immunological abnormality Disease, more significantly change as the hemorheological property of psoriatic has.

2. skin lesion, abnormal results: constitutional skin lesion constitutional skin lesion be dermatosis directly occur in its pathological process and The first skin lesion occurred, Secondary cases skin lesion be constitutional skin lesion through scratching, infecting, treatment processes and in infringement repair process The skin lesion developed.

3. Wa Semanization reaction, abnormal results's course of disease is the longest, and symptom is flickering, and its natural process is divided into three rank Section: first stage, human body do not feels, erythema, pimple, ulceration occurs in Virus entry position, and these symptoms experience a period of time Can " spontaneous recovery ".Enter second stage, virus amount reproduction in blood, skin and mucosa occur recalling rose pityriasis, silver Bits disease, the erythema of acne, blood rash, maculopapule etc..

Drug therapy 1. antibiotics, tetracycline, erythromycin, metronidazole.2. vitamins, vitamin B complex, compound dimension Raw element B, vitamin A.3. retinoid, 13-is along retinoic acid.4. endocrine preparation: gonadal hormone: diethylstilbestrol, chorion rush property Glandular hormone, Progesterone；Antiandrogen: spironolactone sheet, JIAQINGMIGUA PIAN；Corticosteroid hormone: prednisone sheet.5. zinc system Agent, has capsule of licorsinc, sulphuric acid zinc metal sheet, zinc gluconate tablets at present.6. treatment by Chinese herbs pimples can use traditional Chinese medical herbal treatment, effect More satisfactory.Simultaneously it should be noted that diet and living habit.

Medical material involved in the present invention all seen from be recorded in " China book on Chinese herbal medicine ".

Summary of the invention

It is desirable to provide a kind of medicine for treating pimples, by selecting suitable medical material and proportioning thereof, reach Safely and effectively cure the purpose of pimples.

In order to achieve the above object, the present invention is by the following technical solutions:

A kind of medicine for treating pimples, it is characterised in that it is to be prepared from by the raw medicinal material of following weight proportion: male Semen Glycines 9 parts, Herba Carpesii Cernui 15 parts, temperature Folium Isatidis 10 parts, toothbrush grass 9 parts, sheep do not eat 9 parts, Rhizoma cimicifugae simplicis 12 parts, Herba Hedyotidis Diffusae 15 parts, ploughshare head Grass 18 parts, black wool 76 parts, Herba Pellioniae repentis 6 parts, 6 parts of Radix Glycyrrhizae.

Illustrate the method have the benefit that below in conjunction with theories of Chinese materia medica

It has been recognised by the inventors that the basic pathogenesis of pimples to be interior-heat flourishing, outward by caused by ailment said due to cold or exposure, but have lung-heat, heat in blood, liver-heat, the deficiency of YIN Dividing of interior-heat.The skin lesion such as pustule belong to wind heat, scorchingly hot caused.The inflammatory symptoms such as acne cystica acne conglobata are inconspicuous, slowly Property process, for the disease of erythema multiforme cold sore.And for example cicatricial acne can be because of caused by energy stagnation and blood stasis.Treat suitable clearing away heat and eliminating dampness purging FU-organs, and battalion Dissipating phlegm and resolving masses.

The present invention uses: Cassia javanica L. var. indo-chinensis Gagn. heat-clearing and toxic substances removing, intestine moistening of regulating the flow of vital energy；Herba Carpesii Cernui heat-clearing and toxic substances removing, reducing swelling and alleviating pain；Temperature Folium Isatidis heat clearing away Removing toxic substances, blood cooling and ecchymoses removing；Toothbrush grass dissipates and induces sweat, clearing away heat-damp and promoting diuresis；Sheep does not eat heat-clearing and toxic substances removing, dampness；Rhizoma cimicifugae simplicis delivers rash, heat clearing away Removing toxic substances, rises and lifts clear sun；Herba Hedyotidis Diffusae heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain；Herba violae patrinii heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling；Black wool seven Dispel the wind and regulate the flow of vital energy, promoting blood circulation and detoxication；Herba Pellioniae repentis clearing away heat-damp and promoting diuresis.Radix Glycyrrhizae heat-clearing and toxic substances removing, protects stomach regulating the spleen and stomach, the mediation property of medicine.All medicines share, altogether Play clearing away heat and eliminating dampness purging FU-organs, and the merit of battalion's dissipating phlegm and resolving masses.

Below in conjunction with clinical laboratory data beneficial effects of the present invention is described:

1, physical data

Inventor collects 98 example pimples patients between 2012 05 month-2013 years 05 month altogether.16 ~ 36 years old age, 24 years old mean age. It is randomly divided into: treatment group 58 example, matched group 40 example.Treatment group 58 example, male 34 examples, female 24 example；Matched group 40 example, male 26 examples, female 14 examples.The data such as two groups of sexes, age, courses of disease there was no significant difference, and has comparability.

Diagnostic criteria

1. primary disease is common in youth of both sexes, how to occur in pubarche.

2. acne with face, the skin lesion such as upper breast, the acne at back etc., pimple, pustule is as cardinal symptom.

The most all kinds of skin lesion, but several exist simultaneously, also can inversion of phases mutually, most patients are with seborrhea.Most patients No conscious sympton, if can cause pain and tenderness when inflammation is obvious.

1. inclusive criteria meets primary disease diagnostic criteria；See that tuberosity, cyst person include in.2. age 16 ~ 45 years old；3. stop making With the oral and external application medicine relevant with this disease treatment and other Therapeutic Method；4. informed consent the person that signs Informed Consent Form.

Exclusion standard 1. allergic constitution person；Scar diathesis person；2. psychotic；3. diabetes, hemophilia it are associated with Person；4. pregnancy women.

2, Therapeutic Method

Treatment group is administered orally the capsule that the present invention prepares according to specific embodiment 3, three times a day.Treat 30 days.

Matched group is administered orally viaminate, 25mg, three times a day；The each 35mg of zinc gluconate tablets, day 3 times, taking medicine after meal.Treatment 30 days.

3, criterion of therapeutical effect and therapeutic outcome

3.1 criterion of therapeutical effect

1. recovery from illness: the skin lesion such as acne, pimple, pustule go down more than 90%, and skin flattens and only leaves pigment；

The most effective: the skin lesion such as acne, pimple, pustule go down 50% to 90%；

The most effective: the skin lesion such as acne, pimple, pustule go down 30% to 50%；

The most invalid: the skin lesion such as acne, pimple, pustule go down ＜ 30%.

3.2 treatment statistical results are shown in Table 1.

1 liang of table group comparitive study

Group	n	Recovery from illness	Effective	Effectively	Invalid	Total effective rate (%)	Obvious adverse reaction example
								Treatment group	58	17	31	10	0	100%	0
Matched group	40	6	15	10	9	77.5%	0

Visible, pimples can safely and effectively be treated by the medicine that the present invention prepares, and cure rate is high.

Detailed description of the invention

In order to be more fully understood that and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Embodiment 1

Weigh: Cassia javanica L. var. indo-chinensis Gagn. 9 grams, Herba Carpesii Cernui 15 grams, temperature Folium Isatidis 10 grams, toothbrush grass 9 grams, sheep do not eat 9 grams, Rhizoma cimicifugae simplicis 12 grams, tang Grass 15 grams, Herba violae patrinii 18 grams, black wool 76 grams, Herba Pellioniae repentis 6 grams, 6 grams of Radix Glycyrrhizae；Add 8 times amount water, decoct 1.5 hours, filter；Filtering residue Add 6 times amount water, decoct 1 hour, filter；Merging filtrate, is concentrated into 120 grams, must meet the decoct of one day consumption of adult normal.

For treating pimples.Oral, the most once.

Embodiment 2

Weigh: Cassia javanica L. var. indo-chinensis Gagn. 9 grams, Herba Carpesii Cernui 15 grams, temperature Folium Isatidis 10 grams, toothbrush grass 9 grams, sheep do not eat 9 grams, Rhizoma cimicifugae simplicis 12 grams, tang Grass 15 grams, Herba violae patrinii 18 grams, black wool 76 grams, Herba Pellioniae repentis 6 grams, 6 grams of Radix Glycyrrhizae；Add 10 times amount water, decoct 2 hours, filter；Filtering residue Add 8 times amount water, decoct 1.5 hours, filter；Merging filtrate, concentrates, and is dried, and packaging must meet one day consumption of adult normal Powder.

For treating pimples.Oral, every bu is taken for twice sooner or later.

Embodiment 3

Weigh: Cassia javanica L. var. indo-chinensis Gagn. 9 grams, Herba Carpesii Cernui 15 grams, temperature Folium Isatidis 10 grams, toothbrush grass 9 grams, sheep do not eat 9 grams, Rhizoma cimicifugae simplicis 12 grams, tang Grass 15 grams, Herba violae patrinii 18 grams, black wool 76 grams, Herba Pellioniae repentis 6 grams, 6 grams of Radix Glycyrrhizae；Add 6 times amount water, decoct 3 times, decoct 1 little every time Time, merge decoction liquor, concentrate, be dried, load capsule shells, the capsule of one day consumption of adult normal must be met.

For treating pimples.Oral, every bu morning, noon and afternoon take for three times.

Claims

1. the medicine being used for treating pimples, it is characterised in that it is to be prepared from by the raw medicinal material of following weight proportion: Cassia javanica L. var. indo-chinensis Gagn. 9 parts, Herba Carpesii Cernui 15 parts, temperature Folium Isatidis 10 parts, toothbrush grass 9 parts, sheep do not eat 9 parts, Rhizoma cimicifugae simplicis 12 parts, Herba Hedyotidis Diffusae 15 parts, ploughshare Head grass 18 parts, black wool 76 parts, Herba Pellioniae repentis 6 parts, 6 parts of Radix Glycyrrhizae.

2. the medicine for treating pimples as claimed in claim 1, it is characterised in that its preparation method is: weigh: Cassia javanica L. var. indo-chinensis Gagn. 9 parts, Herba Carpesii Cernui 15 parts, temperature Folium Isatidis 10 parts, toothbrush grass 9 parts, sheep do not eat 9 parts, Rhizoma cimicifugae simplicis 12 parts, Herba Hedyotidis Diffusae 15 parts, Herba violae patrinii 18 Part, black wool 76 parts, Herba Pellioniae repentis 6 parts, 6 parts of Radix Glycyrrhizae；Add 8 times amount water, decoct 1.5 hours, filter；Filtering residue adds 6 times amount water, decocts 1 Hour, filter；Merging filtrate, is concentrated into 120 parts, obtains decoct；Above-mentioned part each means weight portion.

3. the medicine for treating pimples as claimed in claim 1, it is characterised in that its preparation method is: weigh: Cassia javanica L. var. indo-chinensis Gagn. 9 parts, Herba Carpesii Cernui 15 parts, temperature Folium Isatidis 10 parts, toothbrush grass 9 parts, sheep do not eat 9 parts, Rhizoma cimicifugae simplicis 12 parts, Herba Hedyotidis Diffusae 15 parts, Herba violae patrinii 18 Part, black wool 76 parts, Herba Pellioniae repentis 6 parts, 6 parts of Radix Glycyrrhizae；Add 10 times amount water, decoct 2 hours, filter；Filtering residue adds 8 times amount water, decocts 1.5 hours, filter；Merging filtrate, concentrates, and is dried, and packaging obtains powder；Above-mentioned part each means weight portion.

4. the medicine for treating pimples as claimed in claim 1, it is characterised in that its preparation method is: weigh: Cassia javanica L. var. indo-chinensis Gagn. 9 parts, Herba Carpesii Cernui 15 parts, temperature Folium Isatidis 10 parts, toothbrush grass 9 parts, sheep do not eat 9 parts, Rhizoma cimicifugae simplicis 12 parts, Herba Hedyotidis Diffusae 15 parts, Herba violae patrinii 18 Part, black wool 76 parts, Herba Pellioniae repentis 6 parts, 6 parts of Radix Glycyrrhizae；Add 6 times amount water, decoct 3 times, decoct 1 hour every time, merge decoction liquor, dense Contracting, is dried, and loads capsule shells, obtains capsule；Above-mentioned part each means weight portion.