CN105832392A - Degradable shape memory rib internal fixing body - Google Patents
Degradable shape memory rib internal fixing body Download PDFInfo
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- CN105832392A CN105832392A CN201510016063.0A CN201510016063A CN105832392A CN 105832392 A CN105832392 A CN 105832392A CN 201510016063 A CN201510016063 A CN 201510016063A CN 105832392 A CN105832392 A CN 105832392A
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- rib
- shape memory
- fixed body
- main part
- shape
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Abstract
A degradable shape memory rib internal fixing body relates to medical equipment for thoracic surgery or orthopedics, and particularly relates to a fracture fixation device for achieving rib fracture internal fixation by using a degradable shape memory material. The degradable shape memory rib internal fixing body includes a main body portion with a plurality of barbs and blunt end cone-shaped head portions arranged at two ends of the main body portion. When the temperature of the fixing body is less than the phase inversion temperature, the fixing body keeps a temporary shape, and is of a cylindrical body with a flat outer peripheral surface and the blunt end cone-shaped head portions at two ends of the main body portion, and the fixing body can be smoothly arranged in a marrow cavity of the rib from a fraction end; the fixing body returns to an initial shape after being arranged in the marrow cavity, and then the fixing body become the cylindrical body with the outer peripheral surface having the bards and inverse thorns at two ends of the cylindrical body, the bards and the inverse thorns penetrate to the inner wall of the marrow cavity of the rib, and then ribs at two sides of the fraction end are fixed on the two ends of the main body portion. Through the shape memory effect, internal fixation of the fraction end can be achieved, connection is firm and is not prone to displacement, placement operation is easy to operate without special surgical instruments, the medical cost can be decreased, and the pain of a patient can be relieved.
Description
Technical field
The present invention relates to thoracic surgery or orthopedic medical device or equipment, particularly relate to one and utilize degradable shape-memory material
Fracture fixation equipment fixing in realizing fracture of rib.
Background technology
Fracture of rib is modal wound type in thoracic injury, accounts for more than the 60% of thoracic injury.Fracture of rib is controlled
The method treated is more, has expectant treatment and the big class of operative treatment two.For the fracture of rib that rib para-position is undesirable to line,
Particularly do not make the flail chest patient that anatomy resets, generally require surgical menopause.
The method of surgical menopause fracture of rib has multiple at present, such as fixing in Kirschner wire, steel wire, pottery nail and rib steel
Plate, steel wire bundle are fixed, fracture with memory alloy embrace fixator rib is fixed, absorbable rib nail is interior fixes.Wherein it can absorb rib
Nail internal fixation treatment fracture of rib is that a kind of damage is little, it is not necessary to the method that second operation takes out, extensive by clinicist
Accept.The absorbable rib nail of Clinical practice includes that Poly-L-lactic acid can absorb rib intramedullary pin, fructus crotonis (GRAND at present
FIXTM) absorbable rib nails etc., by inserting absorbable rib nail after expanding marrow in art, then suture after rib is drawn in para-position over to one's side
Reinforce fracture site.Chinese utility model patent " absorbable rib intramedullary pin " (utility model patent number:
ZL201020547119.8, authorizes publication No.: CN201894668U) disclose the conjunction of a kind of medical magnesium absorbed by degradable
The absorbable rib intramedullary pin that gold is made, described rib intramedullary pin is the arcuate structure that two ends tilt, and rivet nut surface is provided with anti-
De-agnail, described anticreep agnail is in a certain angle with rivet nut, both sides draw in rivet nut center, and described rivet nut two ends are cone
The blunt nosed structure of shape.This utility model has plasticity, according to rib radian random molding, and can degradation in vivo can inhale
Receive, absorb potruncus CT, MRI and check without impact；Histocompatibility is good, taking-up of need not again performing the operation.Though these equipment
So having anti-skidding band or anticreep agnail, but the most automatically do not shrink fixing function, it is fixing the most firm to exist, Yi Yi
Position, generally requires suture again and reinforces fracture site, the most not only can affect the blood supply of periosteum, affects the healing of fracture, also
The intercostal nerves pressurized making to be positioned at rib lower edge can be affected, cause postoperative pain.Chinese invention patent application " can inhale by one
Receiving fracture fixation body " (invention is specially for (application for a patent for invention number: 201310033265.7), " a kind of Combined rib fixer "
Profit application number: 201110269350.4) and " degradable rib fixer " (application for a patent for invention number: 201110363086.0),
Disclose some rib fracture fixing apparatus materials being fixed fracture site by the method outside overall parcel fracture, these devices
The use of material equally exists affects the blood supply of periosteum, affect union of fracture and the postoperative problem causing pain.Due to these devices
The fixation postures of material, outside rib, also can cause fixed position out-of-flatness impact attractive in appearance.
Chinese invention patent " bidirectional shape memory polymer composite material and preparation method thereof " (patent of invention number: ZL
200610136572.8 Authorization Notice No.: CN101164770B) disclose a kind of polymerization with bidirectional shape memory effect
Thing composite and preparation method thereof, this polymer composites by have the polymeric material of shape memory function with can
The elastomeric material superposition actively replied is viscous and forms, and has bidirectional shape memory effect.The shape of this polymer composites
Memory recovery temperature scope is big, can obtain the double of difformity recovery temperature by selecting different shape-memory polymers
To shape memory function, concurrent deformation amount is big, has a preferable bidirectional shape memory function, and its bidirectional shape memory
Performance can be obtained by the thickness etc. of adjustable shape memory polymer thickness with elastomeric material.But, this polymer is combined
Material is not belonging to Biodegradable material, cannot be used for because it does not possesses histocompatibility manufacturing the orthopaedics that degradable absorbs
Fixation device.
Summary of the invention
It is an object of the invention to provide fixed body in a kind of degradable shape memory rib, utilize Biodegradable high-molecular multiple
The shape memory function of condensation material, it is achieved the oneself of fracture site resets and shrinks fixation, solves in the marrow of fracture of rib
Stable fixing technical problem.
The present invention solves above-mentioned technical problem and be the technical scheme is that
Fixed body in a kind of degradable shape memory rib, by with the main part of some barbs be positioned at main part two ends
Blunt nosed cone head is constituted, it is characterised in that:
Described fixed body is made up of biodegradable shape memory macromolecule composite material, and its phase transition temperature is higher than medical
Cold closet refrigerated storage temperature and less than normal human's body temperature；
When the temperature of described fixed body is less than phase transition temperature, described fixed body is maintained at the temporary shapes of shape memory；
After described fixed body is inserted in the pulp cavity of rib, its temperature is increased to more than phase transition temperature, and described fixed body is subject to
To thermal stimulus, automatically it is returned to the original shape of shape memory from temporary shapes；
Be in the fixed body of temporary shapes be rendered as that outer surface is smooth, two ends with the column of blunt nosed cone head, can
Pass through in the pulp cavity that fracture site inserts rib；The main part extension elongation of described fixed body, its radial dimension is shunk
To the pulp cavity internal diameter less than fracture site；Described barb is rounding state, entirely attaches to the outer surface of main part,
The many agnails at main part two ends close up, and form the head of blunt nosed taper；
It is in the fixed body of original shape and is rendered as outer surface with barb, two ends with the post of the agnail upheld to periphery
Shape body, described barb and agnail thrust the pulp cavity inwall of rib simultaneously, are fixedly secured by the rib of fracture site both sides
The two ends of main part；Under the restoring force effect of shape memory effect, described barb stretches out main part outer surface, main body
The split head at two ends, portion is the many agnails upheld to periphery, the main part expanded radially of described fixed body contraction in length,
The rib of traction fracture site both sides is adjacent to each other and firmly closes up.
The one preferably technical scheme of fixed body in the degradable shape memory rib of the present invention, at the two of described main part
End is respectively arranged with 2～8 barbs, is distributed in the main part outer surface near head, and formation can thrust rib pulp cavity inwall automatically
Junction point.
A kind of superior technique scheme of fixed body in the degradable shape memory rib of the present invention, it is characterised in that described master
Body is designed as solid or hollow structure, and its cross section is circular, ellipse, rectangle or polygon, with in satisfied fracture
Fixing mechanical requirements or shape memory function requirement.
The technical scheme of a kind of improvement of fixed body in the degradable shape memory rib of the present invention, it is characterised in that described can
The phase transition temperature of biodegradation shape memory macromolecule composite material is 25～35 DEG C, can freeze also in Medical refrigerator
Keep temporary shapes, and insert internal after at body temperature under automatically reply original shape.
A kind of preferably technical scheme of fixed body in the degradable shape memory rib of the present invention, it is characterised in that described
The heat that biodegradable shape memory macromolecule composite material is octadecyl acrylate to be made with the copolymer of methacrylate
Cause type shape-memory polymer.
The another kind of preferably technical scheme of fixed body in the degradable shape memory rib of the present invention, it is characterised in that described
Biodegradable shape memory macromolecule composite material be polylactic acid and hexamethylene diisocyanate, 1,4-butanediol block polymerization
The polylactic acid-based composite thermotropic type shape-memory polymer obtained.
The invention has the beneficial effects as follows:
1, fixed body in the degradable shape memory rib of the present invention, utilizes shape memory effect to realize the interior solid of fracture site
Fixed, it is connected firmly and is difficult to displacement, implantation surgery is easy and simple to handle, it is not necessary to particular surgical instrument, it is possible to decrease medical treatment cost.
2, fixed body in the degradable shape memory rib of the present invention, relies on the restoring force of shape memory effect firmly to close up bone
Fracture end, it is not necessary to suture is reinforced, and both will not affect union of fracture because suture affects the blood supply of periosteum, and can avoid again
The intercostal nerves pressurized of rib lower edge causes postoperative pain, alleviates patient suffering.
3, in the degradable shape memory rib of the present invention, fixed body uses biodegradable macromolecular material to make, permissible
Gradually degraded and absorbed, takes out without second operation, does not affect later stage breast CT, MRI inspection.
Accompanying drawing explanation
Fig. 1 be the present invention degradable shape memory rib in the temporary shapes schematic diagram of fixed body；
Fig. 2 be the present invention degradable shape memory rib in the original shape schematic diagram of fixed body；
Fig. 3 be the present invention degradable shape memory rib in the use view of fixed body.
In figure, 1-main part, 2-head, 21-agnail, 3-barb, 4-rib, 5-fracture site.
Detailed description of the invention
For better understanding of the technique scheme of the present invention, carry out the most detailed with embodiment below in conjunction with the accompanying drawings
Thin description.
Fixed body in the degradable shape memory rib of the present invention, by with the main part 1 of some barbs be positioned at main part 1
The blunt nosed cone head 2 at two ends is constituted, by with the main part 1 of some barbs be positioned at the blunt nosed cone at main part 1 two ends
Shape head 2 is constituted, as depicted in figs. 1 and 2；
Described fixed body is made up of biodegradable shape memory macromolecule composite material, and its phase transition temperature Ttrans is high
In Medical refrigerator refrigerated storage temperature and less than normal human's body temperature；
When the temperature of described fixed body is less than phase transition temperature Ttrans, described fixed body is maintained at temporary shapes
(Temporary Shape)；After described fixed body is inserted in the pulp cavity of rib 4, its temperature is increased to phase in version temperature
Degree more than Ttrans, described fixed body, by thermal stimulus, automatically reverts to the original shape (Initial of shape memory
Shape)；
Be in the fixed body of temporary shapes be rendered as that outer surface is smooth, two ends with the column of blunt nosed cone head, can
Pass through in the pulp cavity that fracture site 5 inserts rib 4；Main part 1 extension elongation of described fixed body, its radial ruler
Degree is contracted to the pulp cavity internal diameter less than fracture site, and described barb 3, in rounding state, entirely attaches to main part 1
Outer surface, the many agnails 21 at main part 1 two ends close up, and form the head 2 of blunt nosed taper；As shown in Figure 1；
The fixed body being in original shape is rendered as outer surface with barb 3, two ends with the agnail 21 upheld to periphery
Column, described barb 3 and agnail 21 thrust the pulp cavity inwall of rib 4 simultaneously, by the rib of fracture site 5 both sides
Bone 4 fixedly secures the two ends at main part 1；Under the restoring force effect of shape memory effect, described barb 3 stretches out
Main part 1 outer surface, the head 2 at main part 1 two ends is split into the many agnails 21 upheld to periphery, described fixed body
Main part 1 expanded radially and contraction in length, the rib 4 of traction fracture site 5 both sides is adjacent to each other and firmly close up,
As shown in Figures 2 and 3.
In degradable shape memory rib according to the present invention, the embodiment of fixed body, is respectively arranged with at the two ends of described main part 1
2～8 barbs 3, are distributed in the main part 1 outer surface near head 2, and formation can be thrust in rib 4 pulp cavity automatically
The junction point of wall.In Fig. 1～2, the two ends of main part 1 are respectively arranged with 4 barbs 3, in the both sides of fracture site 5 respectively
Form 4 junction points thrusting rib 4 pulp cavity inwall, see rib 4 and the fracture represented with double dot dash line in Fig. 3 disconnected
End 5.
The embodiment of fixed body in degradable shape memory rib according to the present invention, described main part 1 be designed as solid or
Hollow structure, its cross section is circular, ellipse, rectangle or polygon, with meet Fracture internal fixaiion mechanical requirements or
Person's shape memory function requirement.
The embodiment of fixed body in degradable shape memory rib according to the present invention, described biodegradable shape memory is high
The phase transition temperature Ttrans of molecular composite material is 25～35 DEG C, can freeze and keep temporary transient shape in Medical refrigerator
Shape, and insert internal after at body temperature under automatically reply original shape.
An embodiment of fixed body, described biodegradable shape in degradable shape memory rib according to the present invention
Memory polymer composite is that octadecyl acrylate is poly-with the thermotropic shape memory that the copolymer of methacrylate is made
Compound (Thermo-induced shape memory polymers).
Another embodiment of fixed body, described biodegradable shape in degradable shape memory rib according to the present invention
Shape memory polymer composite is that polylactic acid obtains with hexamethylene diisocyanate (HDI), 1,4-butanediol (BDO) block polymerization
The polylactic acid-based composite thermotropic type shape-memory polymer arrived.
The embodiment of fixed body using method in the degradable shape memory rib of the present invention:
First, the thermotropic shape-memory polymer (Thermo-induced that biodegradable macromolecular material is made is utilized
Shape memory polymers), according to the size of different parts rib medullary cavity, make the degradable shape of different model
Fixed body in memory rib, its original shape (Initial Shape) is as shown in Figure 2.
Perform the Preoperative Method of fixed body implantation in rib, the diastatic fracture broken ends of fractured bone 5, and according to the size of medullary cavity in both sides
Medullary cavity internal drilling, select fixed body in the degradable shape memory rib of suitable model, being heated in vitro can
Apply more than the phase transition temperature (Ttrans) of stress deformation, apply stress and make it change to the temporary shapes shown in Fig. 1
(Temporary Shape): the many agnails 21 at main part 1 two ends are closed up, forms the head 2 of blunt nosed taper；Will
Main part 1 stretching makes its extension, and its radial dimension is contracted to the pulp cavity internal diameter of slightly smaller than fracture site, applies simultaneously
Pressure makes the smooth outer surface being affixed to main part 1 of all of barb 3；Main part 1 is bent to and rib 4 fractures
The arc that position is consistent.Fixed body in the rib of temporary shapes will be deformed into cool to rapidly the low-temperature space of below Ttrans subsequently,
Making its Cryopreservation is the temporary shapes after deforming.
Then, rapidly the fixed body saving as temporary shapes is implanted two broken ends of fractured bone of fracture and temporarily fixed, body to be fixed
Temperature arrives at body temperature, and fixed body is returned to original shape, it may be assumed that the main part 1 of fixed body radially automatic expansion is replied
To the radial dimension of original shape, the head 2 at two ends splits into the many agnails 21 upheld to periphery, thrusts rib 4
Pulp cavity inwall, meanwhile, the barb 3 at main part 1 two ends stretches out main part 1 outer surface, thrusts the pulp cavity inwall of rib 4,
The rib 4 of fracture site 5 both sides, under the common effect of agnail 21 and barb 3, fixedly secures the two ends at main part 1；
Meanwhile, described main part 1 shortens the length being returned to original shape vertically, and the restoring force in shape memory effect draws
Under, the rib 4 of fracture site 5 both sides is adjacent to each other and firmly closes up.Fixed being difficult to of fracture site 5 shifts, no
Need suture to reinforce fracture end, union of fracture will not be affected because suture affects the blood supply of periosteum, also not result under rib
The intercostal nerves pressurized of edge causes postoperative pain.After fracture site 5 healing, in the degradable shape memory rib of the present invention
Fixed body can gradually degraded and absorbed, take out without second operation, absorb potruncus CT, MRI and check without impact.
Those of ordinary skill in the art is it should be appreciated that above embodiment is intended merely to illustrate the skill of the present invention
Art scheme, and it is not used as limitation of the invention, any connotation based on the present invention is to embodiment described above
The change made, modification, all will fall in the scope of the claims of the present invention.
Claims (6)
1. a fixed body in degradable shape memory rib, by with the main part of some barbs be positioned at main part two ends
Blunt nosed cone head is constituted, it is characterised in that:
Described fixed body is made up of biodegradable shape memory macromolecule composite material, and its phase transition temperature is higher than medical
Cold closet refrigerated storage temperature and less than normal human's body temperature；
When the temperature of described fixed body is less than phase transition temperature, described fixed body is maintained at the temporary transient shape of shape memory
Shape；After described fixed body is inserted in the pulp cavity of rib, its temperature is increased to more than phase transition temperature, described
Fixed body, by thermal stimulus, is returned to the original shape of shape memory automatically from temporary shapes；
Be in the fixed body of temporary shapes be rendered as that outer surface is smooth, two ends with the column of blunt nosed cone head, can
Pass through in the pulp cavity that fracture site inserts rib；The main part extension elongation of described fixed body, its radial dimension
It is contracted to the pulp cavity internal diameter less than fracture site；Described barb is rounding state, entirely attaches to main part
Outer surface, the many agnails at main part two ends close up, and form the head of blunt nosed taper；
It is in the fixed body of original shape and is rendered as outer surface with barb, two ends with the post of the agnail upheld to periphery
Shape body, described barb and agnail thrust the pulp cavity inwall of rib simultaneously, and the rib of fracture site both sides is firmly solid
It is scheduled on the two ends of main part；Under the restoring force effect of shape memory effect, described barb stretches out main part appearance
Face, the split head at main part two ends is the many agnails upheld to periphery, and the main part of described fixed body is the most swollen
Swollen and contraction in length, the rib of traction fracture site both sides is adjacent to each other and firmly closes up.
Fixed body in degradable shape memory rib the most according to claim 1, be respectively arranged with at the two ends of described main part 2～
8 barbs, are distributed in the main part outer surface near head, form the company that can automatically thrust rib pulp cavity inwall
Contact.
Fixed body in degradable shape memory rib the most according to claim 1, it is characterised in that described main part designs
For solid or hollow structure, its cross section is circular, ellipse, rectangle or polygon, to meet Fracture internal fixaiion
Mechanical requirements or shape memory function requirement.
Fixed body in degradable shape memory rib the most according to claim 1, it is characterised in that described biodegradable
The phase transition temperature of shape memory macromolecule composite material is 25～35 DEG C, can freeze and keep in Medical refrigerator
Temporary shapes, and insert internal after at body temperature under automatically reply original shape.
5. according to fixed body, its feature in the degradable shape memory rib described in any claim of Claims 1-4
It is that described biodegradable shape memory macromolecule composite material is octadecyl acrylate and methacrylate
The thermotropic shape-memory polymer made of copolymer.
6. according to fixed body, its feature in the degradable shape memory rib described in any claim of Claims 1-4
It is that described biodegradable shape memory macromolecule composite material is polylactic acid and hexamethylene diisocyanate, 1,4-fourth
Diol block is polymerized the polylactic acid-based composite thermotropic type shape-memory polymer obtained.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510016063.0A CN105832392A (en) | 2015-01-13 | 2015-01-13 | Degradable shape memory rib internal fixing body |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510016063.0A CN105832392A (en) | 2015-01-13 | 2015-01-13 | Degradable shape memory rib internal fixing body |
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| CN105832392A true CN105832392A (en) | 2016-08-10 |
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Family Applications (1)
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| CN201510016063.0A Pending CN105832392A (en) | 2015-01-13 | 2015-01-13 | Degradable shape memory rib internal fixing body |
Country Status (1)
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111685861A (en) * | 2019-03-13 | 2020-09-22 | 田大为 | Degradable shape memory femoral internal fixation body |
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| US20030060788A1 (en) * | 2001-07-24 | 2003-03-27 | Topolkaraev Vasily A. | Methods of making disposable products having humidity activated materials with shape-memory |
| US6575973B1 (en) * | 2000-10-26 | 2003-06-10 | Safedrip Ltd. | Self locking intramedullary nail |
| CN1569261A (en) * | 2004-05-13 | 2005-01-26 | 哈尔滨工业大学 | Novel use of ploy-L-lactic acid as medical shape memory material |
| US20060190036A1 (en) * | 2003-07-30 | 2006-08-24 | Eberhard-Karls-Universitaet Teubingen | Sealing plug for an opening in a wall of a vessel or hollow organ |
| CN201064479Y (en) * | 2007-08-09 | 2008-05-28 | 王平山 | Anatomy type caput radius intramedullary nail with lock |
| CN101730551A (en) * | 2007-04-19 | 2010-06-09 | 史密夫和内修有限公司 | orientated polymeric devices |
| CN101953709A (en) * | 2010-09-29 | 2011-01-26 | 上海交通大学医学院附属第三人民医院 | Absorbable rib intramedullary nail |
| CN204500924U (en) * | 2015-01-13 | 2015-07-29 | 上海市同济医院 | A kind of degradable shape memory rib internal fixtion body |
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2015
- 2015-01-13 CN CN201510016063.0A patent/CN105832392A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6281262B1 (en) * | 1998-11-12 | 2001-08-28 | Takiron Co., Ltd. | Shape-memory, biodegradable and absorbable material |
| US6575973B1 (en) * | 2000-10-26 | 2003-06-10 | Safedrip Ltd. | Self locking intramedullary nail |
| US20030060788A1 (en) * | 2001-07-24 | 2003-03-27 | Topolkaraev Vasily A. | Methods of making disposable products having humidity activated materials with shape-memory |
| US20060190036A1 (en) * | 2003-07-30 | 2006-08-24 | Eberhard-Karls-Universitaet Teubingen | Sealing plug for an opening in a wall of a vessel or hollow organ |
| CN1569261A (en) * | 2004-05-13 | 2005-01-26 | 哈尔滨工业大学 | Novel use of ploy-L-lactic acid as medical shape memory material |
| CN101730551A (en) * | 2007-04-19 | 2010-06-09 | 史密夫和内修有限公司 | orientated polymeric devices |
| CN201064479Y (en) * | 2007-08-09 | 2008-05-28 | 王平山 | Anatomy type caput radius intramedullary nail with lock |
| CN101953709A (en) * | 2010-09-29 | 2011-01-26 | 上海交通大学医学院附属第三人民医院 | Absorbable rib intramedullary nail |
| CN204500924U (en) * | 2015-01-13 | 2015-07-29 | 上海市同济医院 | A kind of degradable shape memory rib internal fixtion body |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111685861A (en) * | 2019-03-13 | 2020-09-22 | 田大为 | Degradable shape memory femoral internal fixation body |
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Application publication date: 20160810 |