CN105769151B - A kind of pulse wave of multiple points detection method and device - Google Patents

A kind of pulse wave of multiple points detection method and device Download PDF

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Publication number
CN105769151B
CN105769151B CN201610105270.8A CN201610105270A CN105769151B CN 105769151 B CN105769151 B CN 105769151B CN 201610105270 A CN201610105270 A CN 201610105270A CN 105769151 B CN105769151 B CN 105769151B
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pulse wave
wave signal
signal
pulse
way
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CN105769151A (en
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王玲
战鹏弘
张弛
李淑宇
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DANYANG HUICHUANG MEDICAL EQUIPMENT Co.,Ltd.
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Beihang University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/02108Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/7246Details of waveform analysis using correlation, e.g. template matching or determination of similarity

Abstract

A kind of pulse wave of multiple points detection method and device of the present invention, pass through two-way pulse wave signal at acquisition human body wrist, and low-pass filtering is successively carried out to two-way pulse wave signal, solves pulse signal period, construction Periodic Rectangular pulse, constraint independent component analysis, the interference for eliminating the motion artifacts in pulse signal obtains the pulse wave signal of without motion interference.Simultaneously using gloves as carrier, installation reflective photoelectric sensor and data transmission module carry out the acquisition and transmission of pulse wave signal on it, receive pulse wave signal by the signal processing module designed in mobile terminal and the corresponding artefact of eliminating of progress is handled.Advantages of the present invention are as follows: cardiovascular system of human body physiologic information more abundant can be obtained from pulse wave signal;It can be good at eliminating the motion artifacts in signal, recover more pulse waveform features.

Description

A kind of pulse wave of multiple points detection method and device
Technical field
The invention belongs to medicine living organism vital signs detection technique fields, are related to the method and dress of a kind of multiple spot detection pulse It sets.
Background technique
The contraction and diastole of human body ventricular cycle lead to the contraction and diastole of aorta, make blood stream pressure in the form of wave It is propagated since aortic root along entire arterial system, this wave is known as pulse wave.It is form that pulse wave is showed, strong The integrated information of degree, rate and the rhythm and pace of moving things etc., largely reflects many physiological and pathologicals in cardiovascular system of human body Haemodynamics feature.Some physiology ginseng of other physiological status such as blood flow, blood pressure can be not only collected by measuring pulse Data and information are examined, and pulse wave itself contains many reference informations with diagnostic value.
Photoplethysmographic as a kind of new pulse detection means, physiological significance it is verified that.Photoelectricity volume Contain the physiologic information abundant such as heart rate, blood pressure, haemodynamics and respiratory rate in pulse wave, if can successfully realize pair The acquisition and analysis of photoplethysmographic under human motion state, then can really realize the wearable of pulse detecting device.
In recent years, domestic and international wearable device had obtained quick development, and " wearable " has no longer been a concept.Material The development of material technology and sensor technology allows the acquisition of a variety of physiological signals to be possibly realized, but because wearable device positions Carried in people's daily life, so collected physiological signal inevitably can by the interference of the various daily routines of human body, Greatly reduce available human body physiologic information abundant in signal, this causes many wearable devices that can only become a kind of decoration Product.Therefore, the interference of movement how to be inhibited to become an emphasis of wearable device research.
The acquisition of current wearable pulse wave signal focuses primarily upon a bit, and multidigit is at wrist, muscle and rouge at wrist Fat is relatively smaller, and radial artery is close to body surface, convenient for the detection of photoplethysmographic.But just for the pulse wave of a position Signal is detected, and the cardiovascular system information not only contained is less, but also is difficult to eliminate motion artifacts in pulse wave signal.By In the interference of motion artifacts, the available wave character of pulse wave signal greatly reduces, and current wearable pulse detection is caused to set It is standby that heart rate is confined to mostly to the acquisition of human body physiological parameter, it is very limited to the assessment of human body cardiovascular physiology state.
Existing motion artifacts removing method mainly has: traditional frequency domain filtering, mobile mean filter, sef-adapting filter, Time frequency analysis (small echo, empirical mode decomposition etc.), independent component analysis (ICA) etc., and developed on the basis of these algorithms Branch out.
Independent component analysis (ICA) is a kind of method calculated using Statistics, it is a linear transformation.This A transformation is Signal separator at the linear combination in the non-Gaussian signal source of statistical iteration.Due to pulse wave signal and motion artifacts it Between have good statistical independence, so preferable effect can be reached by isolating pulse wave signal by independent component analysis.Solely Vertical constituent analysis needs at least two-way observation signal that can just extract the pulse ingredient in observation signal.
Summary of the invention
The present invention proposes a pulse wave of multiple points detection method and device, is detected by multiple spot and obtains multichannel pulse at wrist Wave signal can not only obtain the physiologic information of cardiovascular system of human body more abundant from multiple signals, and be directed to multichannel Signal can eliminate the motion artifacts in signal using independent composition analysis algorithm, extract normal pulse wave signal.
The present invention proposes a kind of pulse wave of multiple points detection method, is completed by following step:
A kind of multiple spot pulse detection method, it is characterised in that: realized by following step:
Step 1: the total two-way pulse wave signal in person's pulse on the wrist cave and two positions of Shenmen point at detection human body wrist.
Step 2: acquisition two-way pulse wave signal.
Step 3: low-pass filtering treatment being carried out to two-way pulse wave signal, filters out high-frequency noise therein.
Step 4: solving the auto-correlation function of pulse wave signal all the way, obtain the cycle T of pulse wave signal.
Step 5: construction schedule is the rectangular wave of T.
Step 6: using the rectangular wave of building as reference input, filtered two-way pulse wave signal being constrained respectively Independent component analysis removes the motion artifacts in two-way pulse wave signal, obtains the pulse wave signal of without motion interference.
It is transmitted for the detection device of above-mentioned multiple spot pulse detection method, including gloves, reflective photoelectric sensor, data Module and signal processing module.Wherein, the wrist position of gloves, there are two reflective photoelectric sensors for stickup;Work as wearing gloves Afterwards, two reflective photoelectric sensors are located at person's pulse on the wrist cave and Shenmen point position at human body wrist.The data transmit mould Block is fixedly installed at the back of the hand of gloves, for acquiring the two-way pulse wave signal of two reflective photoelectric sensors acquisition, and The two-way pulse wave signal of acquisition is converted to digital signal, sends mobile terminal to by way of bluetooth.In mobile terminal Design has signal processing module, handles for realizing the pulse wave signal received, comprising: filters out two-way pulse wave letter High-frequency noise in number;The auto-correlation function for calculating pulse wave signal, obtains the period of pulse wave signal, and construction schedule rectangle Wave;Using the period for T rectangular wave as reference input, constraint independent composition analysis algorithm is carried out to two-way pulse wave signal, it is real Motion artifacts in existing pulse wave signal are eliminated.
The present invention has the advantages that
1, pulse wave of multiple points detection method of the present invention can be from pulse wave by multipath pulse wave signal at acquisition wrist Cardiovascular system of human body physiologic information more abundant is obtained in signal;
2, pulse wave of multiple points detection method of the present invention can be good at disappearing by the Conjoint Analysis of multipath pulse wave signal Except the motion artifacts in signal, more pulse waveform features are recovered;
3, pulse wave of multiple points detection device of the present invention, it is convenient to wear comfortable using the form of gloves, it will not influence wearer Daily routines, can really realize the continuous detection of pulse wave signal under motion state, obtain the pulse wave of without motion interference Signal provides stable signal source for human body cardiovascular information in pulse wave signal.
Detailed description of the invention
Fig. 1 is pulse wave of multiple points detection method flow chart of the present invention;
Fig. 2 is the pulse wave signal with motion artifacts of pulse wave of multiple points detection method of the present invention acquisition;
Fig. 3 is the finally obtained pulse wave signal eliminated after motion artifacts of pulse wave of multiple points detection method of the present invention;
Fig. 4 is pulse wave of multiple points structure of the detecting device schematic diagram of the present invention.
In figure:
1- gloves 2- reflective photoelectric sensor 3- data transmission module
4- signal processing module 5- mobile terminal
Specific embodiment
Below in conjunction with attached drawing, the present invention is described in further detail.
Pulse wave of multiple points detection method of the present invention, as shown in Figure 1, being realized especially by following step:
Step 1: obtaining the total two-way pulse wave signal in person's pulse on the wrist cave and two positions of Shenmen point at human body wrist.
Step 2: acquisition two-way pulse wave signal, but as shown in Fig. 2, subject is continuously acquired in the pulse wave of motion process In signal, hence it is evident that the interference by motion artifacts.
Step 3: low-pass filtering treatment being carried out to two-way pulse wave signal, filters out high-frequency noise therein.
Step 4: since the period of two-way pulse wave signal is identical, solving wherein the auto-correlation of pulse wave signal all the way Function obtains the cycle T of pulse wave signal.
Step 5: the pulse wave signal cycle T obtained according to step 4, construction schedule are T rectangular wave.
Step 6: using the rectangular wave constructed in step 5 as reference input, two-way pulse wave filtered in step 3 being believed Constraint independent component analysis number is carried out respectively, the motion artifacts in two-way pulse wave signal is removed, as shown in figure 3, obtaining no fortune The pulse wave signal all the way of dynamic interference, is shown in the terminal.
For a kind of pulse wave of multiple points detection device of the above method, including gloves 1, reflective photoelectric sensor 2, data Transmission module 3 and signal processing module 4, as shown in Figure 4.
The gloves 1 are used for the daily wearing of human body;On the medial surface of gloves 1, positioned at the wrist position of gloves 1, glue There are two reflective photoelectric sensors 2 for patch;After human body wearing gloves 1, two reflective photoelectric sensors 2 are located at human body Person's pulse on the wrist cave and Shenmen point position at wrist.Above-mentioned gloves 1 use sports type gloves 1, and wrist position has what can be tightened to stretch Contracting band structure is realized and wears fitting closely between latter two reflective photoelectric sensor 2 and human body wrist skin in gloves 1, leads to Cross the pulse wave signal that two reflective photoelectric sensors 2 acquire two positions in person's pulse on the wrist cave and Shenmen point respectively.The data Transmission module 3 is fixedly installed at the back of the hand of gloves 1, for acquiring the two-way pulse of two reflective photoelectric sensors 2 acquisition Wave signal, and the two-way pulse wave signal of acquisition is converted to digital signal, send equal mobile terminals 5 to by way of bluetooth (such as mobile phone or tablet computer).Design has signal processing module 4 in the mobile terminal 5, for realizing to the pulse received Wave signal is handled, comprising: filters out the high-frequency noise in two-way pulse wave signal using low-pass filter;Calculate pulse wave letter Number auto-correlation function, obtain the period of pulse wave signal, and with construction schedule rectangular wave;Using the period for T rectangular wave as Reference input carries out constraint independent composition analysis algorithm to two-way pulse wave signal, realizes the movement in two-way pulse wave signal Artefact is eliminated, and the pulse wave signal all the way of without motion interference is obtained.
In conclusion pulse wave of multiple points detection method and device of the present invention, are able to detect under motion state at wrist two The pulse wave signal of position carries out constraint independent component analysis to two-way pulse wave signal, successfully eliminates in pulse wave signal Motion artifacts.

Claims (1)

1. a kind of pulse wave of multiple points detection method, it is characterised in that: in the wrist position of gloves, there are two reflection type photoelectricities for stickup Sensor;After wearing gloves, two reflective photoelectric sensors are located at person's pulse on the wrist cave and Shenmen acupuncture point at human body wrist It sets;The total two-way pulse wave in person's pulse on the wrist cave and two positions of Shenmen point at human body wrist is detected by two reflective photoelectric sensors Signal;
Data transmission module is fixedly mounted, at the back of the hand of gloves for acquiring the two-way of two reflective photoelectric sensors acquisition Pulse wave signal, and the two-way pulse wave signal of acquisition is converted to digital signal, it is sent to by way of bluetooth mobile whole End;Design has signal processing module in mobile terminal, handles for realizing the pulse wave signal received: including
A: low-pass filtering treatment is carried out to two-way pulse wave signal, filters out high-frequency noise therein;
B: the auto-correlation function of pulse wave signal all the way is solved wherein, the cycle T of pulse wave signal is obtained;
C: construction schedule is the rectangular wave of T;
D: using the rectangular wave of building as reference input, constraint independent element is carried out respectively to filtered two-way pulse wave signal Analysis removes the motion artifacts in two-way pulse wave signal, obtains the pulse wave signal of without motion interference.
CN201610105270.8A 2016-02-25 2016-02-25 A kind of pulse wave of multiple points detection method and device Active CN105769151B (en)

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CN106343987B (en) * 2016-09-29 2018-05-01 中国科学院重庆绿色智能技术研究院 A kind of graphene pulse wave of multiple points monitoring of blood pressure intelligent wearable device
CN107669253A (en) * 2017-11-15 2018-02-09 中国科学院光电研究院 Heart rate and respiratory rate measuring method based on optical spectrum imagers
CN111374646B (en) * 2018-12-28 2021-08-03 清华大学 Non-hardware-dependent pulse condition information acquisition system and method based on smart phone
CN112274121B (en) * 2020-10-28 2022-10-21 河北工业大学 Noninvasive arteriosclerosis detection method and device based on multipath pulse waves
CN113229788B (en) * 2021-03-26 2022-07-19 广东粤港澳大湾区黄埔材料研究院 Pulse wave denoising method and device based on film pressure sensor

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CN103268717A (en) * 2013-04-03 2013-08-28 漳州师范学院 Remote teaching system based on biological signal
CN104739395A (en) * 2015-03-25 2015-07-01 华中科技大学 Human blood pressure predicting method based on pulse waves
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