CN105687918A - Traditional Chinese medicine composition for treating damp-heat type rheumatic fever and preparing method and application of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for treating damp-heat type rheumatic fever and preparing method and application of traditional Chinese medicine composition Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/88—Liliopsida (monocotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8964—Anemarrhena
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses a traditional Chinese medicine composition for treating a damp-heat type rheumatic fever.The traditional Chinese medicine composition is prepared from, by weight, 25-28 parts of coix seeds, 12-16 parts of rhizomes of Chinese atractylode, 5-8 parts of common curculigo rhizomes, 10-13 parts of cortex phellodendri, 4-8 parts of valerian roots, 7-10 parts of fourstamen stephania roots, 18-21 parts of talc, 10-14 parts of silkworm excrement, 13-16 parts of suberect spatholobus stems, 12-15 parts of rhizoma anemarrhenae and 8-12 parts of almond kernels.The invention further discloses a preparing method of the traditional Chinese medicine composition for treating the damp-heat type rheumatic fever.The prepared traditional Chinese medicine composition is remarkable in treatment effect on the damp-heat type rheumatic fever and can radically treat the rheumatic fever, and relapse is not likely to occur after a patient is cured; the traditional Chinese medicine composition is free of toxic or side effects, simple in prescription, low in price and capable of relieving the treatment burden of the patient.
Description
Technical field
The present invention relates to the field of Chinese medicines, specifically a kind of Chinese medicine composition treating damp-heat type rheumatic fever and its production and use。
Background technology
Rheumatic fever is the acute or chronic Shen Xing ICT of a kind of common recurrent exerbation, mainly involves heart, joint, central nervous system, skin and subcutaneous tissue, but the most obvious with heart and joint。Clinical manifestation, can with heating, toxemia, erythra, subcutaneous nodule, chorea etc. based on carditis and arthritis。Rheumatic fever of a great variety, wherein, damp-heat type rheumatic fever is exactly a kind of common rheumatic fever, the cardinal symptom of damp-heat type rheumatic fever is: indistinctive fever, and the whole body is stranded weight, the arthralgia of the extremities and irritability or red and swollen heat pain, or rheumatism tuberosity, subcutaneous hard swollen, or erythema is fused into irregular speckle, or have body to swell; and yellowish or reddish urine, defecate viscid, red tongue; thick, yellow and greasy fur, slippery and rapid pulse。Mainly adopt antibiotic, nonsteroid anti-inflammatory drugs or glucocorticoid to treat currently for rheumatic fever, the surface symptoms that rheumatic fever is mainly caused by this therapeutic modality is treated, cure the symptoms, not the disease, and rheumatic fever disease cannot be eradicated, cause easily recurrence after more, it addition, the poisonous side effect of medicine adopted is big。
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine composition treating damp-heat type rheumatic fever and its production and use, with the problem solving to propose in above-mentioned background technology。
For achieving the above object, the present invention provides following technical scheme:
A kind of Chinese medicine composition treating damp-heat type rheumatic fever, is made up according to the raw material of weight portion of following: Semen Coicis 25-28 part, Rhizoma Atractylodis 12-16 part, Rhizoma Curculiginis 5-8 part, Cortex Phellodendri 10-13 part, Rhizoma et radix valerianae 4-8 part, Radix Stephaniae Tetrandrae 7-10 part, Talcum 18-21 part, silkworm excrement 10-14 part, Caulis Spatholobi 13-16 part, Rhizoma Anemarrhenae 12-15 part, Semen Armeniacae Amarum 8-12 part。
As the further scheme of the present invention: be made up according to the raw material of weight portion of following: Semen Coicis 26-27 part, Rhizoma Atractylodis 13-15 part, Rhizoma Curculiginis 6-7 part, Cortex Phellodendri 11-12 part, Rhizoma et radix valerianae 5-7 part, Radix Stephaniae Tetrandrae 8-9 part, Talcum 19-20 part, silkworm excrement 11-13 part, Caulis Spatholobi 14-15 part, Rhizoma Anemarrhenae 13-14 part, Semen Armeniacae Amarum 9-11 part。
As the present invention further scheme: be made up according to the raw material of weight portion of following: Semen Coicis 26 parts, Rhizoma Atractylodis 14 parts, Rhizoma Curculiginis 6 parts, Cortex Phellodendri 12 parts, Rhizoma et radix valerianae 6 parts, Radix Stephaniae Tetrandrae 9 parts, 20 parts of Talcum, silkworm excrement 12 parts, Caulis Spatholobi 15 parts, the Rhizoma Anemarrhenae 13 parts, 10 parts of Semen Armeniacae Amarum。
The preparation method of the Chinese medicine composition of described treatment damp-heat type rheumatic fever, step is as follows:
1) Semen Coicis, Rhizoma Atractylodis, Rhizoma Curculiginis and Cortex Phellodendri are weighed, after cleaning, dry, pulverize, add the water of 8-10 times amount, decoct 2-3h, it is thus achieved that a decoction liquor and medicinal residues, medicinal residues are added again the water of 5-7 times amount, decoct 0.5-1h, obtain secondary decoction liquor and secondary medicinal residues, secondary medicinal residues are added the edible ethanol of 8-10 times amount, ultrasonic extraction 45-50min, filter, obtain ultrasonic extract, ultrasonic extract, a decoction liquor and secondary decoction liquor are merged, filter, obtain the first mixed liquor, standby；
2) weigh Talcum, after pulverizing, cross 150-200 mesh sieve, it is thus achieved that Talcum fine powder, standby；
3) weigh Rhizoma et radix valerianae, Radix Stephaniae Tetrandrae, silkworm excrement, Caulis Spatholobi, the Rhizoma Anemarrhenae and Semen Armeniacae Amarum, Rhizoma et radix valerianae, Radix Stephaniae Tetrandrae, Caulis Spatholobi, the Rhizoma Anemarrhenae and Semen Armeniacae Amarum are pulverized, add the edible ethanol of 10-12 times amount, and put into the silkworm excrement with gauze parcel, reflux, extract, 1-2h a, it is thus achieved that extracting solution and a residue, again adds the edible ethanol of 6-8 times amount by residue, reflux, extract, 0.5-1h, obtain secondary raffinate and secondary residual, an extracting solution and secondary raffinate are merged, filters, obtain the second mixed liquor, standby；
4) the first mixed liquor and the second mixed liquor being merged, evaporation and concentration is dry cream；
5) after broken for dried cream powder, Talcum fine powder, mix homogeneously will be added, the Chinese medicine composition of damp-heat type rheumatic fever must be treated。
Above-mentioned Chinese medicine composition can be used in the medicine of preparation treatment damp-heat type rheumatic fever。
Compared with prior art, the invention has the beneficial effects as follows:
Chinese medicine composition prepared by the present invention is evident in efficacy to treatment damp-heat type rheumatic fever, fundamentally treats rheumatic fever, controls difficulty in relapse after healing, and have no side effect。Prescription of the present invention is simple, cheap, reduces the treatment burden of patient。
Detailed description of the invention
Below in conjunction with detailed description of the invention, technical scheme is described in more detail。
Embodiment 1
A kind of Chinese medicine composition treating damp-heat type rheumatic fever, is made up according to the raw material of weight portion of following: Semen Coicis 25 parts, Rhizoma Atractylodis 12 parts, Rhizoma Curculiginis 5 parts, Cortex Phellodendri 10 parts, Rhizoma et radix valerianae 4 parts, Radix Stephaniae Tetrandrae 7 parts, 18 parts of Talcum, silkworm excrement 10 parts, Caulis Spatholobi 13 parts, the Rhizoma Anemarrhenae 12 parts, 8 parts of Semen Armeniacae Amarum。
The preparation method treating the Chinese medicine composition of damp-heat type rheumatic fever described in the present embodiment, step is as follows:
1) weigh Semen Coicis, Rhizoma Atractylodis, Rhizoma Curculiginis and Cortex Phellodendri, after cleaning, dry, pulverize, add the water of 8 times amount, decoct 2h, it is thus achieved that a decoction liquor and medicinal residues, medicinal residues are added again the water of 5 times amount, decocts 0.5h, it is thus achieved that secondary decoction liquor and secondary medicinal residues, secondary medicinal residues are added the edible ethanol of 8 times amount, ultrasonic extraction 45min, filters, obtain ultrasonic extract, ultrasonic extract, a decoction liquor and secondary decoction liquor are merged, filter, obtain the first mixed liquor, standby；
2) weigh Talcum, after pulverizing, cross 150 mesh sieves, it is thus achieved that Talcum fine powder, standby；
3) weigh Rhizoma et radix valerianae, Radix Stephaniae Tetrandrae, silkworm excrement, Caulis Spatholobi, the Rhizoma Anemarrhenae and Semen Armeniacae Amarum, Rhizoma et radix valerianae, Radix Stephaniae Tetrandrae, Caulis Spatholobi, the Rhizoma Anemarrhenae and Semen Armeniacae Amarum are pulverized, adds the edible ethanol of 10 times amount, and put into the silkworm excrement with gauze parcel, reflux, extract, 1h a, it is thus achieved that extracting solution and a residue, again adds the edible ethanol of 6 times amount by residue, reflux, extract, 0.5h, obtain secondary raffinate and secondary residual, an extracting solution and secondary raffinate are merged, filters, obtain the second mixed liquor, standby；
4) the first mixed liquor and the second mixed liquor being merged, evaporation and concentration is dry cream；
5) after broken for dried cream powder, Talcum fine powder, mix homogeneously will be added, the Chinese medicine composition of damp-heat type rheumatic fever must be treated。
Embodiment 2
A kind of Chinese medicine composition treating damp-heat type rheumatic fever, is made up according to the raw material of weight portion of following: Semen Coicis 26 parts, Rhizoma Atractylodis 16 parts, Rhizoma Curculiginis 5 parts, Cortex Phellodendri 12 parts, Rhizoma et radix valerianae 8 parts, Radix Stephaniae Tetrandrae 7 parts, 19 parts of Talcum, silkworm excrement 14 parts, Caulis Spatholobi 14 parts, the Rhizoma Anemarrhenae 12 parts, 8 parts of Semen Armeniacae Amarum。
The preparation method treating the Chinese medicine composition of damp-heat type rheumatic fever described in the present embodiment, step is as follows:
1) weigh Semen Coicis, Rhizoma Atractylodis, Rhizoma Curculiginis and Cortex Phellodendri, after cleaning, dry, pulverize, add the water of 9 times amount, decoct 2.5h, it is thus achieved that a decoction liquor and medicinal residues, medicinal residues are added again the water of 7 times amount, decocts 1h, it is thus achieved that secondary decoction liquor and secondary medicinal residues, secondary medicinal residues are added the edible ethanol of 10 times amount, ultrasonic extraction 48min, filters, obtain ultrasonic extract, ultrasonic extract, a decoction liquor and secondary decoction liquor are merged, filter, obtain the first mixed liquor, standby；
2) weigh Talcum, after pulverizing, cross 180 mesh sieves, it is thus achieved that Talcum fine powder, standby；
3) weigh Rhizoma et radix valerianae, Radix Stephaniae Tetrandrae, silkworm excrement, Caulis Spatholobi, the Rhizoma Anemarrhenae and Semen Armeniacae Amarum, Rhizoma et radix valerianae, Radix Stephaniae Tetrandrae, Caulis Spatholobi, the Rhizoma Anemarrhenae and Semen Armeniacae Amarum are pulverized, adds the edible ethanol of 11 times amount, and put into the silkworm excrement with gauze parcel, reflux, extract, 2h a, it is thus achieved that extracting solution and a residue, again adds the edible ethanol of 6 times amount by residue, reflux, extract, 0.5h, obtain secondary raffinate and secondary residual, an extracting solution and secondary raffinate are merged, filters, obtain the second mixed liquor, standby；
4) the first mixed liquor and the second mixed liquor being merged, evaporation and concentration is dry cream；
5) after broken for dried cream powder, Talcum fine powder, mix homogeneously will be added, the Chinese medicine composition of damp-heat type rheumatic fever must be treated。
Embodiment 3
A kind of Chinese medicine composition treating damp-heat type rheumatic fever, is made up according to the raw material of weight portion of following: Semen Coicis 26 parts, Rhizoma Atractylodis 14 parts, Rhizoma Curculiginis 6 parts, Cortex Phellodendri 12 parts, Rhizoma et radix valerianae 6 parts, Radix Stephaniae Tetrandrae 9 parts, 20 parts of Talcum, silkworm excrement 12 parts, Caulis Spatholobi 15 parts, the Rhizoma Anemarrhenae 13 parts, 10 parts of Semen Armeniacae Amarum。
The preparation method treating the Chinese medicine composition of damp-heat type rheumatic fever described in the present embodiment, step is as follows:
1) weigh Semen Coicis, Rhizoma Atractylodis, Rhizoma Curculiginis and Cortex Phellodendri, after cleaning, dry, pulverize, add the water of 9 times amount, decoct 2.5h, it is thus achieved that a decoction liquor and medicinal residues, medicinal residues are added again the water of 6 times amount, decocts 0.5h, it is thus achieved that secondary decoction liquor and secondary medicinal residues, secondary medicinal residues are added the edible ethanol of 9 times amount, ultrasonic extraction 48min, filters, obtain ultrasonic extract, ultrasonic extract, a decoction liquor and secondary decoction liquor are merged, filter, obtain the first mixed liquor, standby；
2) weigh Talcum, after pulverizing, cross 180 mesh sieves, it is thus achieved that Talcum fine powder, standby；
3) weigh Rhizoma et radix valerianae, Radix Stephaniae Tetrandrae, silkworm excrement, Caulis Spatholobi, the Rhizoma Anemarrhenae and Semen Armeniacae Amarum, Rhizoma et radix valerianae, Radix Stephaniae Tetrandrae, Caulis Spatholobi, the Rhizoma Anemarrhenae and Semen Armeniacae Amarum are pulverized, adds the edible ethanol of 11 times amount, and put into the silkworm excrement with gauze parcel, reflux, extract, 1.5h a, it is thus achieved that extracting solution and a residue, again adds the edible ethanol of 7 times amount by residue, reflux, extract, 1h, obtain secondary raffinate and secondary residual, an extracting solution and secondary raffinate are merged, filters, obtain the second mixed liquor, standby；
4) the first mixed liquor and the second mixed liquor being merged, evaporation and concentration is dry cream；
5) after broken for dried cream powder, Talcum fine powder, mix homogeneously will be added, the Chinese medicine composition of damp-heat type rheumatic fever must be treated。
Embodiment 4
A kind of Chinese medicine composition treating damp-heat type rheumatic fever, is made up according to the raw material of weight portion of following: Semen Coicis 27 parts, Rhizoma Atractylodis 16 parts, Rhizoma Curculiginis 6 parts, Cortex Phellodendri 10 parts, Rhizoma et radix valerianae 8 parts, Radix Stephaniae Tetrandrae 8 parts, 21 parts of Talcum, silkworm excrement 10 parts, Caulis Spatholobi 14 parts, the Rhizoma Anemarrhenae 15 parts, 8 parts of Semen Armeniacae Amarum。
The preparation method treating the Chinese medicine composition of damp-heat type rheumatic fever described in the present embodiment, step is as follows:
1) weigh Semen Coicis, Rhizoma Atractylodis, Rhizoma Curculiginis and Cortex Phellodendri, after cleaning, dry, pulverize, add the water of 8 times amount, decoct 2.5h, it is thus achieved that a decoction liquor and medicinal residues, medicinal residues are added again the water of 7 times amount, decocts 0.5h, it is thus achieved that secondary decoction liquor and secondary medicinal residues, secondary medicinal residues are added the edible ethanol of 10 times amount, ultrasonic extraction 50min, filters, obtain ultrasonic extract, ultrasonic extract, a decoction liquor and secondary decoction liquor are merged, filter, obtain the first mixed liquor, standby；
2) weigh Talcum, after pulverizing, cross 200 mesh sieves, it is thus achieved that Talcum fine powder, standby；
3) weigh Rhizoma et radix valerianae, Radix Stephaniae Tetrandrae, silkworm excrement, Caulis Spatholobi, the Rhizoma Anemarrhenae and Semen Armeniacae Amarum, Rhizoma et radix valerianae, Radix Stephaniae Tetrandrae, Caulis Spatholobi, the Rhizoma Anemarrhenae and Semen Armeniacae Amarum are pulverized, adds the edible ethanol of 10 times amount, and put into the silkworm excrement with gauze parcel, reflux, extract, 1h a, it is thus achieved that extracting solution and a residue, again adds the edible ethanol of 8 times amount by residue, reflux, extract, 1h, obtain secondary raffinate and secondary residual, an extracting solution and secondary raffinate are merged, filters, obtain the second mixed liquor, standby；
4) the first mixed liquor and the second mixed liquor being merged, evaporation and concentration is dry cream；
5) after broken for dried cream powder, Talcum fine powder, mix homogeneously will be added, the Chinese medicine composition of damp-heat type rheumatic fever must be treated。
Embodiment 5
A kind of Chinese medicine composition treating damp-heat type rheumatic fever, is made up according to the raw material of weight portion of following: Semen Coicis 28 parts, Rhizoma Atractylodis 16 parts, Rhizoma Curculiginis 8 parts, Cortex Phellodendri 13 parts, Rhizoma et radix valerianae 8 parts, Radix Stephaniae Tetrandrae 10 parts, 21 parts of Talcum, silkworm excrement 14 parts, Caulis Spatholobi 16 parts, the Rhizoma Anemarrhenae 15 parts, 12 parts of Semen Armeniacae Amarum。
The preparation method treating the Chinese medicine composition of damp-heat type rheumatic fever described in the present embodiment, step is as follows:
1) weigh Semen Coicis, Rhizoma Atractylodis, Rhizoma Curculiginis and Cortex Phellodendri, after cleaning, dry, pulverize, add the water of 10 times amount, decoct 3h, it is thus achieved that a decoction liquor and medicinal residues, medicinal residues are added again the water of 7 times amount, decocts 1h, it is thus achieved that secondary decoction liquor and secondary medicinal residues, secondary medicinal residues are added the edible ethanol of 10 times amount, ultrasonic extraction 50min, filters, obtain ultrasonic extract, ultrasonic extract, a decoction liquor and secondary decoction liquor are merged, filter, obtain the first mixed liquor, standby；
2) weigh Talcum, after pulverizing, cross 200 mesh sieves, it is thus achieved that Talcum fine powder, standby；
3) weigh Rhizoma et radix valerianae, Radix Stephaniae Tetrandrae, silkworm excrement, Caulis Spatholobi, the Rhizoma Anemarrhenae and Semen Armeniacae Amarum, Rhizoma et radix valerianae, Radix Stephaniae Tetrandrae, Caulis Spatholobi, the Rhizoma Anemarrhenae and Semen Armeniacae Amarum are pulverized, adds the edible ethanol of 12 times amount, and put into the silkworm excrement with gauze parcel, reflux, extract, 2h a, it is thus achieved that extracting solution and a residue, again adds the edible ethanol of 8 times amount by residue, reflux, extract, 1h, obtain secondary raffinate and secondary residual, an extracting solution and secondary raffinate are merged, filters, obtain the second mixed liquor, standby；
4) the first mixed liquor and the second mixed liquor being merged, evaporation and concentration is dry cream；
5) after broken for dried cream powder, Talcum fine powder, mix homogeneously will be added, the Chinese medicine composition of damp-heat type rheumatic fever must be treated。
Comparative example
It is made up according to the raw material of weight portion of following: Semen Coicis 26 parts, Rhizoma Atractylodis 14 parts, Rhizoma Curculiginis 6 parts, Cortex Phellodendri 12 parts, Radix Stephaniae Tetrandrae 9 parts, 20 parts of Talcum, silkworm excrement 12 parts, Caulis Spatholobi 15 parts, the Rhizoma Anemarrhenae 13 parts, 10 parts of Semen Armeniacae Amarum。
Curative effect
1, damp-heat type rheumatic fever patient totally 268 example made a definite diagnosis, this 268 example patient is randomly divided into two groups, respectively experimental group and matched group, often organizes 134 people。
Experimental group patient all takes the Chinese medicine composition of the treatment damp-heat type rheumatic fever prepared by embodiment 3, oral, every day three times, 15 days courses for the treatment of, carries out the treatment of five courses for the treatment of。
Matched group patient all takes the prescription drug of comparative example, decoction, and potion, divided and took for three times, 15 days courses for the treatment of, carry out the treatment of five courses for the treatment of every day。
2, the cardinal symptom of damp-heat type rheumatic fever is: indistinctive fever, and the whole body is stranded weight, the arthralgia of the extremities and irritability or red and swollen heat pain or rheumatism tuberosity, subcutaneous hard swollen, or erythema is fused into irregular speckle, or has body to swell, and yellowish or reddish urine is defecated viscid, red tongue, thick, yellow and greasy fur, slippery and rapid pulse。In this, as judging that whether patient is the foundation of damp-heat type rheumatic fever disease。
3, therapeutic outcome
Experimental group 134 example patient is after the treatment of five courses for the treatment of, and wherein 93 example patients cure, and 40 example patients take a turn for the better, and only the state of an illness of 1 example patient is without significant change, and cure rate is 69.4%, and total effective rate is 99.3%。
Matched group 134 example patient is after the treatment of five courses for the treatment of, and wherein 75 example patients cure, and 32 example patients take a turn for the better, and the state of an illness of 27 example patients is without significant change, and cure rate is 56.0%, and total effective rate is 80.0%。
It can be seen that the therapeutic effect of experimental group is substantially better than matched group from treatment Comparative result。And comparative example is compared with embodiment 3, without Rhizoma et radix valerianae, and adopt conventional decoction。It can therefore be seen that the present invention is by adding Rhizoma et radix valerianae, Rhizoma et radix valerianae and other component compatibilities, and adopt preparation method of the present invention, be conducive to improving drug effect。
Chinese medicine composition prepared by the present invention is evident in efficacy to treatment damp-heat type rheumatic fever, fundamentally treats rheumatic fever, controls difficulty in relapse after healing, and have no side effect。Prescription of the present invention is simple, cheap, reduces the treatment burden of patient。
Above the better embodiment of the present invention is explained in detail, but the present invention is not limited to above-mentioned embodiment, in the ken that one skilled in the relevant art possesses, it is also possible under the premise without departing from present inventive concept, make various change。
Claims (5)
1. the Chinese medicine composition treating damp-heat type rheumatic fever, it is characterized in that, be made up according to the raw material of weight portion of following: Semen Coicis 25-28 part, Rhizoma Atractylodis 12-16 part, Rhizoma Curculiginis 5-8 part, Cortex Phellodendri 10-13 part, Rhizoma et radix valerianae 4-8 part, Radix Stephaniae Tetrandrae 7-10 part, Talcum 18-21 part, silkworm excrement 10-14 part, Caulis Spatholobi 13-16 part, Rhizoma Anemarrhenae 12-15 part, Semen Armeniacae Amarum 8-12 part。
2. the Chinese medicine composition for the treatment of damp-heat type rheumatic fever according to claim 1, it is characterized in that, be made up according to the raw material of weight portion of following: Semen Coicis 26-27 part, Rhizoma Atractylodis 13-15 part, Rhizoma Curculiginis 6-7 part, Cortex Phellodendri 11-12 part, Rhizoma et radix valerianae 5-7 part, Radix Stephaniae Tetrandrae 8-9 part, Talcum 19-20 part, silkworm excrement 11-13 part, Caulis Spatholobi 14-15 part, Rhizoma Anemarrhenae 13-14 part, Semen Armeniacae Amarum 9-11 part。
3. the Chinese medicine composition for the treatment of damp-heat type rheumatic fever according to claim 2, it is characterized in that, be made up according to the raw material of weight portion of following: Semen Coicis 26 parts, Rhizoma Atractylodis 14 parts, Rhizoma Curculiginis 6 parts, Cortex Phellodendri 12 parts, Rhizoma et radix valerianae 6 parts, Radix Stephaniae Tetrandrae 9 parts, 20 parts of Talcum, silkworm excrement 12 parts, Caulis Spatholobi 15 parts, the Rhizoma Anemarrhenae 13 parts, 10 parts of Semen Armeniacae Amarum。
4. one kind as arbitrary in claim 1-3 as described in the preparation method of Chinese medicine composition for the treatment of damp-heat type rheumatic fever, it is characterised in that step is as follows:
1) Semen Coicis, Rhizoma Atractylodis, Rhizoma Curculiginis and Cortex Phellodendri are weighed, after cleaning, dry, pulverize, add the water of 8-10 times amount, decoct 2-3h, it is thus achieved that a decoction liquor and medicinal residues, medicinal residues are added again the water of 5-7 times amount, decoct 0.5-1h, obtain secondary decoction liquor and secondary medicinal residues, secondary medicinal residues are added the edible ethanol of 8-10 times amount, ultrasonic extraction 45-50min, filter, obtain ultrasonic extract, ultrasonic extract, a decoction liquor and secondary decoction liquor are merged, filter, obtain the first mixed liquor, standby；
2) weigh Talcum, after pulverizing, cross 150-200 mesh sieve, it is thus achieved that Talcum fine powder, standby；
3) weigh Rhizoma et radix valerianae, Radix Stephaniae Tetrandrae, silkworm excrement, Caulis Spatholobi, the Rhizoma Anemarrhenae and Semen Armeniacae Amarum, Rhizoma et radix valerianae, Radix Stephaniae Tetrandrae, Caulis Spatholobi, the Rhizoma Anemarrhenae and Semen Armeniacae Amarum are pulverized, add the edible ethanol of 10-12 times amount, and put into the silkworm excrement with gauze parcel, reflux, extract, 1-2h a, it is thus achieved that extracting solution and a residue, again adds the edible ethanol of 6-8 times amount by residue, reflux, extract, 0.5-1h, obtain secondary raffinate and secondary residual, an extracting solution and secondary raffinate are merged, filters, obtain the second mixed liquor, standby；
4) the first mixed liquor and the second mixed liquor being merged, evaporation and concentration is dry cream；
5) after broken for dried cream powder, Talcum fine powder, mix homogeneously will be added, the Chinese medicine composition of damp-heat type rheumatic fever must be treated。
5. the purposes in the medicine of preparation treatment damp-heat type rheumatic fever of the Chinese medicine composition as described in as arbitrary in claim 1-3。
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106421324A (en) * | 2016-12-09 | 2017-02-22 | 于巧媛 | Traditional Chinese medicine composition for treating phlegm-stagnation and heat-arthralgia type rheumatic fever |
| CN106511808A (en) * | 2016-12-09 | 2017-03-22 | 于巧媛 | Traditional Chinese medicine composition for treating cold-dampness pyretic arthralgia type rheumatic fever |
| CN108686088A (en) * | 2017-04-08 | 2018-10-23 | 乔兰萍 | Chinese medicine leads to kidney and dissipates prescription and preparation process |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194460A (en) * | 2015-10-22 | 2015-12-30 | 刘凯 | Traditional Chinese medicine preparation for treating acute episode stage of wind-damp-heat type gout |
-
2016
- 2016-04-27 CN CN201610267869.1A patent/CN105687918A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194460A (en) * | 2015-10-22 | 2015-12-30 | 刘凯 | Traditional Chinese medicine preparation for treating acute episode stage of wind-damp-heat type gout |
Non-Patent Citations (1)
| Title |
|---|
| 娄多峰: "《娄多峰痹证治验》", 28 February 2013, 中国医药科技出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106421324A (en) * | 2016-12-09 | 2017-02-22 | 于巧媛 | Traditional Chinese medicine composition for treating phlegm-stagnation and heat-arthralgia type rheumatic fever |
| CN106511808A (en) * | 2016-12-09 | 2017-03-22 | 于巧媛 | Traditional Chinese medicine composition for treating cold-dampness pyretic arthralgia type rheumatic fever |
| CN108686088A (en) * | 2017-04-08 | 2018-10-23 | 乔兰萍 | Chinese medicine leads to kidney and dissipates prescription and preparation process |
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Application publication date: 20160622 |