CN105663851A - 一种治疗口腔溃疡的中药组合物 - Google Patents
一种治疗口腔溃疡的中药组合物 Download PDFInfo
- Publication number
- CN105663851A CN105663851A CN201610131899.XA CN201610131899A CN105663851A CN 105663851 A CN105663851 A CN 105663851A CN 201610131899 A CN201610131899 A CN 201610131899A CN 105663851 A CN105663851 A CN 105663851A
- Authority
- CN
- China
- Prior art keywords
- parts
- herba
- chinese medicine
- medicine composition
- oral ulcer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 47
- 208000002399 aphthous stomatitis Diseases 0.000 title claims abstract description 29
- 208000007117 Oral Ulcer Diseases 0.000 title claims abstract description 26
- 239000000203 mixture Substances 0.000 title claims abstract description 25
- 239000002994 raw material Substances 0.000 claims abstract description 12
- 241000628997 Flos Species 0.000 claims abstract description 11
- 239000004863 Frankincense Substances 0.000 claims abstract description 11
- 241000717739 Boswellia sacra Species 0.000 claims description 10
- 241001299553 Ilex chinensis Species 0.000 claims description 10
- 241001100935 Ilex purpurea Species 0.000 claims description 10
- 235000003366 Ilex purpurea Nutrition 0.000 claims description 10
- QYZBCWXZSYTIOY-UHFFFAOYSA-N Mercuric oxide Chemical compound [O-2].[Hg+2] QYZBCWXZSYTIOY-UHFFFAOYSA-N 0.000 claims description 10
- 230000000694 effects Effects 0.000 abstract description 26
- 230000001737 promoting effect Effects 0.000 abstract description 12
- 239000008280 blood Substances 0.000 abstract description 11
- 210000004369 blood Anatomy 0.000 abstract description 11
- 210000000952 spleen Anatomy 0.000 abstract description 7
- 238000005469 granulation Methods 0.000 abstract description 5
- 230000003179 granulation Effects 0.000 abstract description 5
- 230000035876 healing Effects 0.000 abstract description 5
- 210000003734 kidney Anatomy 0.000 abstract description 5
- 238000001816 cooling Methods 0.000 abstract description 4
- 238000001035 drying Methods 0.000 abstract description 4
- 210000004185 liver Anatomy 0.000 abstract description 4
- 238000010926 purge Methods 0.000 abstract description 2
- 241001313857 Bletilla striata Species 0.000 abstract 1
- 235000003717 Boswellia sacra Nutrition 0.000 abstract 1
- 235000012035 Boswellia serrata Nutrition 0.000 abstract 1
- 240000007551 Boswellia serrata Species 0.000 abstract 1
- 241000220457 Crotalaria Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 244000219416 Hypericum japonicum Species 0.000 abstract 1
- 235000002710 Ilex cornuta Nutrition 0.000 abstract 1
- 241001310146 Ilex cornuta Species 0.000 abstract 1
- 241001290537 Lepironia Species 0.000 abstract 1
- 240000003915 Lophatherum gracile Species 0.000 abstract 1
- 235000010326 Osmanthus heterophyllus Nutrition 0.000 abstract 1
- 241000691155 Pteris multifida Species 0.000 abstract 1
- 235000014220 Rhus chinensis Nutrition 0.000 abstract 1
- 240000003152 Rhus chinensis Species 0.000 abstract 1
- 241001478428 Syngnathus Species 0.000 abstract 1
- 235000018718 Verbena officinalis Nutrition 0.000 abstract 1
- 229940105847 calamine Drugs 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 229910052864 hemimorphite Inorganic materials 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 abstract 1
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
- 235000014692 zinc oxide Nutrition 0.000 abstract 1
- 239000011787 zinc oxide Substances 0.000 abstract 1
- CPYIZQLXMGRKSW-UHFFFAOYSA-N zinc;iron(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[O-2].[Fe+3].[Fe+3].[Zn+2] CPYIZQLXMGRKSW-UHFFFAOYSA-N 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 description 10
- 231100000397 ulcer Toxicity 0.000 description 10
- 230000008961 swelling Effects 0.000 description 6
- 208000004880 Polyuria Diseases 0.000 description 5
- 230000035619 diuresis Effects 0.000 description 5
- 230000023597 hemostasis Effects 0.000 description 5
- 230000000306 recurrent effect Effects 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 230000007812 deficiency Effects 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 231100000614 poison Toxicity 0.000 description 4
- 239000003440 toxic substance Substances 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 3
- 238000009835 boiling Methods 0.000 description 3
- 210000002200 mouth mucosa Anatomy 0.000 description 3
- 210000004877 mucosa Anatomy 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 230000017423 tissue regeneration Effects 0.000 description 3
- 206010011224 Cough Diseases 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 2
- 208000013403 hyperactivity Diseases 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 208000027496 Behcet disease Diseases 0.000 description 1
- 208000009137 Behcet syndrome Diseases 0.000 description 1
- 206010006326 Breath odour Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 206010060891 General symptom Diseases 0.000 description 1
- 208000032139 Halitosis Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 208000000440 Herpetic Stomatitis Diseases 0.000 description 1
- 206010020601 Hyperchlorhydria Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010028034 Mouth ulceration Diseases 0.000 description 1
- 241000475481 Nebula Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010067152 Oral herpes Diseases 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 239000003212 astringent agent Substances 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 208000035850 clinical syndrome Diseases 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000004195 gingiva Anatomy 0.000 description 1
- 150000002333 glycines Chemical class 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000008093 supporting effect Effects 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/808—Scrophularia (figwort)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/28—Mercury; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/60—Fish, e.g. seahorses; Fish eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Marine Sciences & Fisheries (AREA)
- Inorganic Chemistry (AREA)
- Insects & Arthropods (AREA)
- Zoology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种治疗口腔溃疡的中药组合物，其中药原料及重量份配比为：玄参10-30份、石龙刍5-25份、淡竹叶5-25份、白芨5-20份、黄柏5-25份、凤尾草10-30份、海龙5-25份、海螵蛸10-30份、马鞭草5-25份、四季青10-30份、野菊花5-25份、响铃草5-20份、乳香5-20份、炉甘石5-25份、田基黄10-30份、五倍子5-25份、升药5-20份、小蓟5-25份、甘草5-15份。本发明的中药组合物具有滋肾养肝、补脾益气、清热燥湿、泻火解毒、凉血滋阴、生肌敛疮的功效，其治疗口腔溃疡疗效显著，作用可靠。
Description
技术领域
本发明涉及一种传统草药的未确定结构的医药配制品，尤其是一种治疗口腔溃疡的中药组合物。
背景技术
口腔溃疡，也称“口疮”，是发生在口腔黏膜上的表浅性溃疡，大小可从米粒至黄豆大小、成圆形或卵形，溃疡表面为凹、周围充血。溃疡具有周期性、复发性及自限性等特点，好发于唇、颊、舌缘等。同时伴有并发症，可并发口臭、牙龈红肿、慢性咽炎、便秘、头痛、头晕、恶心、乏力、烦躁、发热、淋巴结肿大等全身症状。口腔溃疡多在秋季及气候突变时容易复发。临床西医治疗此病以补充维生素及消炎为主,但都疗效欠佳且大多数患者的口腔溃疡会在很短的时间内反复发作。
中医认为，口腔溃疡多由心脾积热、胃火上炎、阴虚火旺、脾虚湿盛引起。临床辨证可分为心脾积热、阴虚火旺、气血亏虚三个证型。
根据中医理论，针对口腔溃疡的发病机理，采用滋肾养肝、补脾益气、清热燥湿、泻火解毒、凉血滋阴、生肌敛疮的治法，进行辩证配伍组方，以达到标本兼治的目的。
发明内容
为了克服现有技术中治疗口腔溃疡存在疗效欠佳且大多数患者的口腔溃疡会在很短的时间内反复发作的不足，本发明提供一种配制简便、成本低、疗效显著、无副作用的治疗口腔溃疡的中药组合物。
本发明解决其技术问题所采用的技术方案是：一种治疗口腔溃疡的中药组合物，其特征在于：其中药原料及重量份配比为：玄参10-30份、石龙刍5-25份、淡竹叶5-25份、白芨5-20份、黄柏5-25份、凤尾草10-30份、海龙5-25份、海螵蛸10-30份、马鞭草5-25份、四季青10-30份、野菊花5-25份、响铃草5-20份、乳香5-20份、炉甘石5-25份、田基黄10-30份、五倍子5-25份、升药5-20份、小蓟5-25份、甘草5-15份。
本发明的优选技术方案是：一种治疗口腔溃疡的中药组合物，其特征在于：其中药原料及重量份配比为：玄参20份、石龙刍15份、淡竹叶15份、白芨10份、黄柏15份、凤尾草20份、海龙15份、海螵蛸20份、马鞭草15份、四季青20份、野菊花15份、响铃草10份、乳香10份、炉甘石15份、田基黄20份、五倍子15份、升药10份、小蓟15份、甘草10份。
本发明中药组合物是在传统中医理论和临床经验指导下，精选药物组方。本发明中药组合物中：玄参具有凉血滋阴、泻火解毒的功效；石龙刍具有利水通淋、泄热、安神、凉血止血的功效；淡竹叶具有清热除烦、利尿的功效；白芨具有收敛止血、消肿生肌的功效；黄柏具有清热燥湿、泻火除蒸、解毒疗疮的功效；凤尾草具有清热利湿、凉血止血、消肿解毒的功效；海龙具有补肾壮阳、散结消肿的功效；海螵蛸具有收敛止血、固精止带、制酸止痛、收湿敛疮的功效；马鞭草具有清热解毒、活血散瘀、利水消肿的功效；四季青具有清热解毒、生肌敛疮、活血止血的功效；野菊花具有疏风清热、消肿解毒的功效；响铃草具有滋肾养肝、止咳平喘、利湿解毒的功效；乳香具有活血行气、止痛、消肿生肌的功效；炉甘石具有明目去翳、收湿止痒、敛疮生肌的功效；田基黄具有清热利湿、解毒、散瘀消肿的功效；五倍子具有敛肺降火、涩肠止泻、敛汗止血、收湿敛疮的功效；升药具有排脓拔毒、去腐生肌的功效；小蓟具有凉血止血、祛瘀消肿的功效；甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明精选药物组方，其药物组分经辩证配伍，在作用上相互佐助，共奏滋肾养肝、补脾益气、清热燥湿、泻火解毒、凉血滋阴、生肌敛疮的功效，对口腔溃疡的治疗达到标本兼治。
本发明组合物的组分均采用天然的中药原料，其配制简便、药源广、成本低。本发明遵循中医的处方用药原则，各种组分药物采用水煎服用。经临床应用验证，其疗效显著可靠，药性平和，未出现毒副作用，有效率达94%，治愈率71%。
具体实施方式
下面结合实施例对本发明作进一步说明。
实施例1
一种治疗口腔溃疡的中药组合物，其中药原料及重量配比为：玄参20g、石龙刍15g、淡竹叶15g、白芨10g、黄柏15g、凤尾草20g、海龙15g、海螵蛸20g、马鞭草15g、四季青20g、野菊花15g、响铃草10g、乳香10g、炉甘石15g、田基黄20g、五倍子15g、升药10g、小蓟15g、甘草10g。
实施例2
一种治疗口腔溃疡的中药组合物，其中药原料及重量配比为：玄参10g、石龙刍20g、淡竹叶5g、白芨15g、黄柏10g、凤尾草25g、海龙5g、海螵蛸30g、马鞭草10g、四季青25g、野菊花5g、响铃草15g、乳香12g、炉甘石25g、田基黄10g、五倍子20g、升药5g、小蓟25g、甘草12g。
实施例3
一种治疗口腔溃疡的中药组合物，其中药原料及重量配比为：玄参25g、石龙刍5g、淡竹叶20g、白芨12g、黄柏25g、凤尾草10g、海龙20g、海螵蛸15g、马鞭草25g、四季青10g、野菊花20g、响铃草12g、乳香15g、炉甘石5g、田基黄25g、五倍子10g、升药20g、小蓟5g、甘草15g。
实施例4
一种治疗口腔溃疡的中药组合物，其中药原料及重量配比为：玄参15g、石龙刍25g、淡竹叶10g、白芨20g、黄柏5g、凤尾草30g、海龙10g、海螵蛸25g、马鞭草5g、四季青30g、野菊花10g、响铃草20g、乳香5g、炉甘石20g、田基黄10g、五倍子25g、升药15g、小蓟10g、甘草5g。
实施例5
一种治疗口腔溃疡的中药组合物，其中药原料及重量配比为：玄参30g、石龙刍10g、淡竹叶25g、白芨5g、黄柏20g、凤尾草15g、海龙25g、海螵蛸10g、马鞭草20g、四季青15g、野菊花25g、响铃草5g、乳香20g、炉甘石10g、田基黄30g、五倍子5g、升药12g、小蓟20g、甘草8g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下：将组方的中药原料放入容器中，加冷水漫过药面，浸泡15～20分钟，再加水没过药面约6厘米，进行第一次煎煮，未沸前采用武火煎煮，沸后用文火煎煮20～30分钟；第二次煎煮，加水没过药面约4厘米，水沸后煎煮15～20分钟。两次煎煮取汁，合并。
本发明以实施例1所给出的一种治疗口腔溃疡的中药组合物，做临床疗效总结如下：
一、一般性资料：本中药组合物应用于临床观察病例100例，男58例，女42例，年龄15～65岁。
二、、诊断标准：
1、以口腔粘膜出现单个或数个直径3～5mm的溃疡，灼热疼痛为主要症状；
2、起病较快，一般7天左右愈合，若此伏彼起，则病程延长。愈后常易复发；
3、口腔检查：口腔粘膜溃疡较表浅，圆形或椭圆形，数量少则1～2个，多则10余个，表面有淡黄色分泌物附着，溃疡周围粘膜大多充血；
4、应与狐惑病（白塞氏综合症）、复发性坏死性粘膜周围炎及疱疹性口腔炎相鉴别。
三、用法用量：临床应用时，一日一剂，水煎两遍取汁约400ml，分早、晚两次空腹温服。六天为一疗程。治疗期间忌生冷辛辣刺激之物。
四、疗效标准：
(1)治愈：口腔溃疡愈合，局部无不适感；
(2)有效：口疮虽然时有复发，但数量减少，程度减轻；
(3)无效：口疮症状及溃疡无明显变化。
五、治疗效果：该临床观察病例中，服药2-5个疗程，痊愈71例，随访未见复发；有效23例，无效6例。治疗期间未发生毒副作用。
六、典型病例：
病例1：
丁某，女，27岁。患复发性口腔溃疡已2年，曾服用多种药物，病情反复发作。口腔检查：口腔粘膜溃疡较表浅，呈椭圆形，数量10余个，表面有淡黄色分泌物附着，溃疡周围粘膜大多充血。服用本发明中药组合物制备的药剂3个疗程，症状消失。随访至今再未复发。
病例2：
姚某，男，49岁。口腔溃疡1年多，口腔粘膜出现数个溃疡，灼热疼痛，吃不好睡不好，吃药，打针，会减轻症状，但是会反复发作。服用本发明中药组合物制备的药剂2个疗程，症状基本消失，继续服用2个疗程，症状完全消失，完全治愈。随访至今再未复发。
Claims (2)
1.一种治疗口腔溃疡的中药组合物，其特征在于：其中药原料及重量份配比为：玄参10-30份、石龙刍5-25份、淡竹叶5-25份、白芨5-20份、黄柏5-25份、凤尾草10-30份、海龙5-25份、海螵蛸10-30份、马鞭草5-25份、四季青10-30份、野菊花5-25份、响铃草5-20份、乳香5-20份、炉甘石5-25份、田基黄10-30份、五倍子5-25份、升药5-20份、小蓟5-25份、甘草5-15份。
2.根据权利要求1所述一种治疗口腔溃疡的中药组合物，其特征在于：其中药原料及重量份配比为：玄参20份、石龙刍15份、淡竹叶15份、白芨10份、黄柏15份、凤尾草20份、海龙15份、海螵蛸20份、马鞭草15份、四季青20份、野菊花15份、响铃草10份、乳香10份、炉甘石15份、田基黄20份、五倍子15份、升药10份、小蓟15份、甘草10份。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610131899.XA CN105663851A (zh) | 2016-03-09 | 2016-03-09 | 一种治疗口腔溃疡的中药组合物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610131899.XA CN105663851A (zh) | 2016-03-09 | 2016-03-09 | 一种治疗口腔溃疡的中药组合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105663851A true CN105663851A (zh) | 2016-06-15 |
Family
ID=56307258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610131899.XA Pending CN105663851A (zh) | 2016-03-09 | 2016-03-09 | 一种治疗口腔溃疡的中药组合物 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105663851A (zh) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106236942A (zh) * | 2016-08-11 | 2016-12-21 | 邢献林 | 治疗口腔溃疡及其它口腔粘膜疾病的中药组合物及其制备方法 |
| CN106265872A (zh) * | 2016-08-22 | 2017-01-04 | 安徽兆龙生物科技有限公司 | 一种利用生物提取物治疗口腔溃疡的药片及其制备方法 |
-
2016
- 2016-03-09 CN CN201610131899.XA patent/CN105663851A/zh active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106236942A (zh) * | 2016-08-11 | 2016-12-21 | 邢献林 | 治疗口腔溃疡及其它口腔粘膜疾病的中药组合物及其制备方法 |
| CN106265872A (zh) * | 2016-08-22 | 2017-01-04 | 安徽兆龙生物科技有限公司 | 一种利用生物提取物治疗口腔溃疡的药片及其制备方法 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104367911B (zh) | 治疗风湿及类风湿性关节炎的中药组合物及其制备方法 | |
| CN103191353B (zh) | 一种治疗手足癣的中药组合物 | |
| CN104013910A (zh) | 一种治疗高血压的中药组合物 | |
| CN103211990B (zh) | 一种治疗口腔溃疡的中药组合物 | |
| CN104758762A (zh) | 一种治疗肺痨的中药组合物 | |
| CN105663851A (zh) | 一种治疗口腔溃疡的中药组合物 | |
| CN104001131A (zh) | 一种防治应激性溃疡的内服中药 | |
| CN105617042A (zh) | 一种治疗头痛的中药组合物 | |
| CN104606471A (zh) | 一种治疗慢性胃炎的中药组合物 | |
| CN105148235A (zh) | 一种治疗产后出血的中药组合物 | |
| CN104888132A (zh) | 一种治疗慢性胃炎的中药组合物 | |
| CN105213831A (zh) | 一种治疗流行性出血热的中药组合物 | |
| CN103007170B (zh) | 一种治疗复发性口腔溃疡的中药组合物 | |
| CN105663850A (zh) | 一种治疗口腔溃疡的中药组合物 | |
| CN102284023A (zh) | 一种治疗喘症的中药组合物 | |
| CN105833152A (zh) | 一种治疗内分泌失调的中药组合物 | |
| CN105617162A (zh) | 一种治疗口疮的中药组合物 | |
| CN105796851A (zh) | 一种治疗激素依赖性皮炎的中药组合物 | |
| CN105477454A (zh) | 一种治疗湿疹的中药组合物 | |
| CN105833093A (zh) | 一种治疗牙周炎的中药组合物 | |
| CN105687899A (zh) | 一种治疗老年斑的中药组合物 | |
| CN105663832A (zh) | 一种治疗放射性皮炎的中药组合物 | |
| CN104758784A (zh) | 一种治疗慢性胃炎的中药组合物 | |
| CN104127709A (zh) | 一种治疗慢性肾功能不全的中药组合物 | |
| CN105770434A (zh) | 一种治疗口腔溃疡的中药组合物 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160615 |