CN105661542A - Lipid-reducing healthcare oil - Google Patents

Lipid-reducing healthcare oil Download PDF

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Publication number
CN105661542A
CN105661542A CN201610032010.2A CN201610032010A CN105661542A CN 105661542 A CN105661542 A CN 105661542A CN 201610032010 A CN201610032010 A CN 201610032010A CN 105661542 A CN105661542 A CN 105661542A
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oil
weight
water
add
parts
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冯旭升
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Jilin Jinheng Pharmaceutical Co Ltd
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Jilin Jinheng Pharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/884Alismataceae (Water-plantain family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The invention relates to lipid-reducing healthcare oil.The lipid-reducing healthcare oil is prepared from traditional Chinese medicinal materials including, by weight, 2-5 parts of Fructus Lycii, 1-4 parts of Fructus Crataegi, 2-4 parts of Semen Ziziphi Spinosae, 2-5 parts of Radix Puerariae, 1.5-3 parts of Semen Cassiae, 1-3 parts of Semen Raphani, 0.5-2 parts of Flos Carthami, 1-3 parts of Folium Mori, 1.5-4 parts of Bulbus Allii Macrostemoni, 0.5-3 parts of Rhizoma Ligustici Wallichii and 1-3 parts of Rhizoma Alismatis.

Description

A kind of Antilipemic health oil
Technical field:
The present invention relates to a kind of edible health oil product, particularly to a kind of Antilipemic health oil product.
Background technology:
Oils and fats is one of requisite food of people's daily life. The local flavor that the requirement of oils and fats not only to have been had by people, but also the requirement of unsoundness and nutrition. Now, good health and a long life have become people's question of common concern, and research and development nourishing healthy oils and fats is also one of focus of oils and fats research in recent years. Traditional view is thought, the major function of oils and fats is to provide nutrition and good local flavor, and occurring of nourishing healthy oils and fats will undoubtedly to the content that oil prodution industry injection is new.
Health protection with Chinese medicine product are based on theory of Chinese medical science, for raw material or add health promoting product prepared by the mode of Chinese herbal medicine extract with Chinese herbal medicine, such as relevant functional health-care food, natural prodcuts, pollution-free food, Organic food, enhancing immunity product, anti-aging product, preventing and treating cardiovascular disease product, antineoplastic product, liver protecting and kidney invigorating product, marine organisms goods, subtract weight gaining health product, aminoacid, hematinic, fatty acid, edible fiber, new resource food, trace element product etc.; Food therapy product: food therapy raw material and relevant device, tonic medical material (ginseng/young pilose antler/Cordyceps etc.), the prepared slices of Chinese crude drugs, national characters medicine and Chinese traditional herbs, crude drug and extract etc.
Edible oil and fat being equipped with Chinese medicine as edible health oil product, current product is less, and the present invention passes through the research to Chinese medical theory and scientific experiments, has invented a kind of health-care oil product with lipid-reducing function.
Summary of the invention:
The present invention provides a kind of Antilipemic health oil, and it is prepared from by the raw material of Chinese medicine medicine of following weight proportion,
Preferably, the Antilipemic health oil of the present invention, it is prepared from by the raw material of Chinese medicine medicine of following weight proportion,
Most preferred, the Antilipemic health oil of the present invention, it is prepared from by the raw material of Chinese medicine medicine of following weight proportion,
The present invention is on the Chinese medicine basis of above proportioning, carries out Chinese crude drug extracting processing, and by oil immersion, decocting in water, oil-water separation, the step such as oil-water emulsion prepares into a kind of edible oil emulsions, i.e. the Antilipemic health oil of the present invention.
Antilipemic health of the present invention oil, its preparation method is as follows:
Step 1,
Chinese crude drug is pulverized, and adds salad oil, and heat-insulation soaking 10-15 hour at 95 DEG C~105 DEG C, then add water fried 2-5h, and oil-water separation, oil phase is standby.
Step 2,
Aqueous phase, adds the activated carbon of 2%~5%, at 85 DEG C~95 DEG C insulated and stirred 1h~2h, concentrates after filtration, and concentrated solution is standby.
Step 3,
In oil phase add Fructus Maydis oil, Oleum Arachidis hypogaeae semen, Oleum sesami, add emulsifying agent, and aqueous phase carries out emulsifying, homogenizing obtain the present invention Antilipemic health oil.
Wherein, the part by weight of four kinds of oils and fatss is as follows
Preferably, the part by weight of four kinds of oils and fatss is as follows
Preferably, the preparation method of the present invention:
Wherein the Chinese crude drug in step 1 first through drying, chopping up, parch, then pulverize, 10~20 orders sieve, and the amount adding salad oil is medical material weight 1.5-2.5 times. Add 0.5-1.5 times that amount is medical material weight of water
The wherein concentration in step 2, selected from vacuum evaporation, steams the water of wherein 80%.
Wherein the emulsifying agent in step 3 is selected from: Span60 and Tween60, antioxidant or preservative can be added if desired, described antioxidant is selected from: the excellent precious TBHQ antioxidant in Guangzhou, make consumption 0.02% (percentage by weight), and add the citric acid of people's a small amount of (about 0.001%) (percentage by weight), preservative is selected from: potassium sorbate 0.1% (percentage by weight)
The formula of the present invention and preparation method obtain through screening, and screening process is as follows:
1 experimental section
Choosing and pharmacology of 1.1 integration of edible and medicinal herbs Chinese crude drugs
1.1.I formula and pharmacology Fructus Lycii, Fructus Crataegi, Semen Ziziphi Spinosae, Radix Puerariae, Semen Cassiae, Semen Raphani, Flos Carthami, Folium Mori, Bulbus Allii Macrostemonis, Rhizoma Chuanxiong, Rhizoma Alismatis.
1.1.2 active substance and recommendation health care consumption in selected Chinese crude drug, in Table 1.
The active substance of table 1 " Antilipemic health oil " Chinese herbal medicine and recommendation health care consumption
" Antilipemic health oil " is the physiological characteristics grown according to " Nian Sishi, half of YIN QI consumed " expectorant stasis of blood and the formula designed. In prescription, Fructus Lycii, Semen Ziziphi Spinosae, Radix Puerariae have yin nourishing benefit essence effect, the effect of invigorating blood circulation of Folium Mori, Bulbus Allii Macrostemonis, Rhizoma Chuanxiong, Rhizoma Alismatis diuresis, Bulbus Allii Macrostemonis, Rhizoma Chuanxiong circulation of qi promoting, Semen Cassiae intestine moistening. Having benefit to have to rush down, remove the rotten and let fresh grow, enhance metabolism, maintain organism balance, full presciption medicine thing all has the effect of blood fat reducing in various degree, blood pressure lowering, blood circulation promoting, therefore the cardiovascular and cerebrovascular disease that person in middle and old age are common is had functions of prevention and health care.
1.2 nourishing healthy oil making technology experiments
1.2.1 the formula of substrate oils and fats
The purpose of formula is to meet the requirement of basic fatty acid composition to improve local flavor and the mouthfeel of health-care oil.
The formula of table 2 substrate oils and fats
Note: salad oil is soybean salad oil or rape salad oil
1.2.2 the extraction process of active substance in selected integration of edible and medicinal herbs medical material
Traditional instructions of taking of Chinese medicine is that decocting in water makes soup, then takes. Making in the process of soup at decocting in water, major part water soluble ingredient enters people's soup, also has part oil-soluble part and aqueous solution to form heterogeneous emulsification system, wherein also has the minimum solid suspension of part, thus common Chinese medicinal decoction is dark muddy liquid. In order to extract effective oil soluble part in Chinese crude drug fully.
The following extraction process of special employing:
Chinese crude drug first through drying, chopping up, parch, then pulverize, 10~20 orders sieve, add the soybean salad oil of medical material weight 2 times, at 95 DEG C~105 DEG C, insulation leaching system is overnight. about 12h, and then add the medical material fried maintenance bottom water of 1 times of weight pure water and be in fluidized state, depress at 1 standard atmosphere, due to upper strata oils and fats, make water boiling point raise, therefore boiling temperature is about 100 DEG C~105 DEG C unlimited boiling 4h, then filters, oils and fats and aqueous solution are through stratification, then are separated. Oils and fats cooling after separately is standby, and the aqueous solution of layering adds the activated carbon of 2%~5%, at 85 DEG C~95 DEG C insulated and stirred 1h~2h, carry out decolouring, taking off taste, refilter, by filter vacuum evaporation and concentration, to remove the water of wherein 80%, the cooling of this concentrated solution is standby.
Main technologic parameters is as follows:
Pulverizing medicinal materials 10 mesh sieve. Oils and fats soaks system oil/medical material anharmonic ratio 2.5:1 ratio conveniently, temperature 95 DEG C~105 DEG C, about 12h. Adding water, water/medical material weight ratio 1.5:1,100 DEG C~105 DEG C decocting in water of temperature, water are for 4h, aqueous phase active carbon for decolorization amount 2%~5% (weight), insulated and stirred 1h~2h at 80 DEG C~95 DEG C. Vacuum concentrates, and under 20kPa vacuum, the moisture of wherein 80% is fallen in concentration.
1.2.3 the selection of emulsifying agent
HLB value needed for emulsifying multiple eating oil is 6~12, selects Span60 and Tween60 to prepare a series of emulsion as emulsifying agent. The HLB of Span60 is the HLB of 4.7, Tween60 is 14.9. Additivity principle according to emulsifier hlb value has prepared a series of emulsifying agent, and tests the required emulsifying agent minimum drawing stable emulsion, and variation tendency is table 3 such as.
Table 3 emulsifier situation of change
Span60 and Tween60 is best as the emulsifying effectiveness of blended emulsifier.
1.2.4 the preparation of emulsion
In the process for preparation of emulsion, be respectively adopted feed way three kinds different and tested, i.e. agent-in-water method, agent-in-oil method and in turn liquid feeding method.
Blended emulsifier, in this method, is directly dissolved in water by agent-in-water method, is added by oil under vigorous stirring and forms.
This method of agent-in-oil method is also known as phase conversion emulsifying or " civil law ". This method is to add in oil phase by blended emulsifier, at Jia Renshui. fierceness is stirred companion and is formed.
This method of liquid feeding method is also known as " admiralty method " in turn. This normal direction water and oil add blended emulsifier in turn, only adds a small amount of every time, after high degree of agitation.
Emulsion prepared by above-mentioned three kinds of modes is carried out stability test, and result is table 4 such as. As shown in Table 4, the most stable with the made emulsion joined of agent-in-oil method.
4 three kinds of distinct methods of table make the stability of emulsion
1.2.5 the screening of antioxidant
For ensureing nourishing healthy oil oxidation stability screening antioxidant, find that the excellent precious TBHQ antioxidant effect in Guangzhou is better, make consumption 0.02% (weight), and add the citric acid of people's a small amount of (about 0.001%), add potassium sorbate 0.1% as preservative, the change of peroxide value and acid number such as table 5 after measured.
The change of over hydrogenation value and acid number after table 5 health-care oil addition TBHQ antioxidant
Note: add the oil sample of people antioxidant TBHQ and potassium sorbate preservative and do not add the blank sample of the above-mentioned additive of people, depositing in the calorstat of 37 DEG C simultaneously, and monthly regular mensuration its cross softness value and acid number.
Can be seen that from upper table, add antioxidant TBHQ and there is obvious antioxidant effect.
2 conclusions
2.1 using the compound lard of 80% soybean salad oil, 2% refined sesame oil, 10% Fructus Maydis oil and the 8% heavy fragrant peanut oil carrier oils and fats as nutrition oil. The fatty acid of this carrier oils and fats forms such as table 6.
The fatty acid composition of table 6 nutrition oil
Choose above-mentioned carrier oils and fats and can also well shelter the bad smell brought into due to Chinese medicine ingredients, and make nutrition oil have good taste and local flavor.
The integration of edible and medicinal herbs medical material that 2.2 screen is as follows: Fructus Lycii, Fructus Crataegi, Semen Ziziphi Spinosae, Radix Puerariae, Semen Cassiae, Semen Raphani, Flos Carthami, Folium Mori, Bulbus Allii Macrostemonis, Rhizoma Chuanxiong, Rhizoma Alismatis.
Chinese crude drug is through cleaning, dry, shred, pulverize, steaming stir-fry, pulverize then through pulverizer, sieve through 10~20 mesh sieve, add the soybean salad oil of 2 times of weight, at 95 DEG C~105 DEG C, 12h processed is soaked in insulation, be subsequently adding 1~1.5 times of deionized water, maintenance water is in slight boiling condition, uncovered fried 4h in bottom, filters through filter plant, by oil phase and aqueous phase stratification, making biphase separating in phase separator, oil phase cools down, and aqueous phase adds 2%~5% activated carbon, 2h is stirred at 80 DEG C~85 DEG C, refilter, filter vacuum is concentrated, remove the water of wherein 80%.
2.3 add other oils and fats by above-mentioned requirements in oil phase, it is subsequently adding the blended emulsifier (wherein be 34%Tween60 and 66%Span65 containing weight ratio) of 0.1% (weight), aqueous phase emulsifying after concentrating with vacuum again, homogenizing 0.5h (rotating speed 14000r/min), it is 0.02% (weight), potassium sorbate 0.1% (weight) by antioxidant TBHQ, sand milling is sheared dispersion 6h~8h add, continue homogenizing 1.5~2h.
2.4 modes pressing carrier oils and fats agent-in-oil method, add nutrition oil prepared by the blended emulsifier (wherein containing 34%Tween60 and 66%Span65) of 0.1, steady quality, have health function.
3 functional experiments
3.1 functional check conclusions: inspection experiments show that, sample can suppress the rising of feed height fat nutrient fodder rat blood serum TG and cholesterol, increases high density lipoprotein, has obvious regulating blood lipid action.
Lipid-lowering test
Lipid determination: the rat blood serum T-CHOL (TC) of rating model group and inventive samples group, triglyceride (TG), LDL-C (LDL-C), highdensity lipoprotein-cholesterol (HDL-C),
Rat fat changes
The each blood lipids index of rat giving medicine of the present invention while feeding high lipid food is clearly better. Wherein, TG, TC and the LDL-C level of heavy dose of experimental group rat is compared model group and is decreased obviously. The HDL-C level of of the present invention group of rat compares model group HDL-C level tool significant difference.
Experimental result is shown in following table:
3.2 toxicological experiments: the Kunming mouse Oral toxicity to two kinds of sexes, gavage concentration reaches 20ml/kg.bw successively, observes one week, does not find poisoning symptom, also without dead, specifies by acute toxicity grading criteria, and this experiment thing belongs to nontoxic level class material. Three mutagenic test results are feminine gender. The composition described above of the present invention is by weight as proportioning, can increase according to corresponding proportion when producing or reduce, as large-scale production can by kilogram in units of, or in units of ton, small-scale production can also in units of milligram, weight can increase or reduce, but the constant rate of the raw medicinal herbs weight proportion between each composition.
The ratio of above weight proportion obtains through science screening, for special circumstances, such as serious symptom or mild, fat or modest, it is possible to the proportioning of the corresponding amount adjusting composition, increases or reduces less than 100%, and drug effect is constant.
The health-care oil of the present invention, can be prepared as pharmaceutical dosage forms as required, as added pharmaceutically acceptable carrier, prepares according to the routine techniques of galenic pharmacy. The pharmaceutical dosage forms of the present invention, it is possible to selected from dosage forms such as capsule, soft gelatin capsules, it is also possible to prepare into oral liquid.
The present invention is found surprisingly that, and the collocation of each component of the present invention has synergistic function, has the health-care effect of blood fat reducing, blood pressure lowering, blood circulation promoting.
Detailed description of the invention:
Further illustrate the present invention by the following examples, but not as limitation of the present invention.
Embodiment 1
The present invention provides a kind of Antilipemic health oil, and it is prepared from by the raw material of Chinese medicine medicine of following weight proportion,
The part by weight of four kinds of oils and fatss is as follows
Preparation method is as follows:
Chinese crude drug is through cleaning, dry, shred, pulverize, steaming stir-fry, pulverize then through pulverizer, sieve through 10~20 mesh sieve, add the soybean salad oil of 2 times of weight, at 95 DEG C~105 DEG C, 12h processed is soaked in insulation, be subsequently adding 1~1.5 times of deionized water, maintenance water is in slight boiling condition, uncovered fried 4h in bottom, filters through filter plant, by oil phase and aqueous phase stratification, making biphase separating in phase separator, oil phase cools down, and aqueous phase adds 2%~5% activated carbon, 2h is stirred at 80 DEG C~85 DEG C, refilter, filter vacuum is concentrated, remove the water of wherein 80%.
Oil phase adds other oils and fats, it is subsequently adding the blended emulsifier (wherein containing 34%Tween60 and 66%Span65) of 0.1% (weight), aqueous phase emulsifying after concentrating with vacuum again, addition antioxidant TBHQ0.02% (weight), potassium sorbate 0.1% (weight) homogenizing 2h (rotating speed 14000r/min), sand milling is sheared dispersion 6h~8h add, continue homogenizing 1.5~2h.
Embodiment 2
The present invention provides a kind of Antilipemic health oil, and it is prepared from by the raw material of Chinese medicine medicine of following weight proportion,
The part by weight of four kinds of oils and fatss is as follows
Preparation method is as follows:
Chinese crude drug is through cleaning, dry, shred, pulverize, steaming stir-fry, pulverize then through pulverizer, sieve through 10~20 mesh sieve, add the soybean salad oil of 2 times of weight, at 95 DEG C~105 DEG C, 12h processed is soaked in insulation, be subsequently adding 1~1.5 times of deionized water, maintenance water is in slight boiling condition, uncovered fried 4h in bottom, filters through filter plant, by oil phase and aqueous phase stratification, making biphase separating in phase separator, oil phase cools down, and aqueous phase adds 2%~5% activated carbon, 2h is stirred at 80 DEG C~85 DEG C, refilter, filter vacuum is concentrated, remove the water of wherein 80%.
Oil phase adds other oils and fats, it is subsequently adding the blended emulsifier (wherein containing 34%Tween60 and 66%Span65) of 0.1% (weight), aqueous phase emulsifying after concentrating with vacuum again, addition antioxidant TBHQ0.02% (weight), potassium sorbate 0.1% (weight) homogenizing 2h (rotating speed 14000r/min), sand milling is sheared dispersion 6h~8h add, continue homogenizing 1.5~2h.
Embodiment 3
The present invention provides a kind of Antilipemic health oil, and it is prepared from by the raw material of Chinese medicine medicine of following weight proportion,
The part by weight of four kinds of oils and fatss is as follows
Preparation method is as follows:
Chinese crude drug is through cleaning, dry, shred, pulverize, steaming stir-fry, pulverize then through pulverizer, sieve through 10~20 mesh sieve, add the soybean salad oil of 2 times of weight, at 95 DEG C~105 DEG C, 12h processed is soaked in insulation, be subsequently adding 1~1.5 times of deionized water, maintenance water is in slight boiling condition, uncovered fried 4h in bottom, filters through filter plant, by oil phase and aqueous phase stratification, making biphase separating in phase separator, oil phase cools down, and aqueous phase adds 2%~5% activated carbon, 2h is stirred at 80 DEG C~85 DEG C, refilter, filter vacuum is concentrated, remove the water of wherein 80%.
Oil phase adds other oils and fats, it is subsequently adding the blended emulsifier (wherein containing 34%Tween60 and 66%Span65) of 0.1% (weight), aqueous phase emulsifying after concentrating with vacuum again, addition antioxidant TBHQ0.02% (weight), potassium sorbate 0.1% (weight) homogenizing 2h (rotating speed 14000r/min), sand milling is sheared dispersion 6h~8h add, continue homogenizing 1.5~2h.
Embodiment 4
Preparation method:
Chinese crude drug is through cleaning, dry, shred, pulverize, steaming stir-fry, pulverize then through pulverizer, sieve through 10~20 mesh sieve, add the soybean salad oil of 2 times of weight, at 95 DEG C~105 DEG C, 12h processed is soaked in insulation, be subsequently adding 1~1.5 times of deionized water, maintenance water is in slight boiling condition, uncovered fried 4h in bottom, filters through filter plant, by oil phase and aqueous phase stratification, making biphase separating in phase separator, oil phase cools down, and aqueous phase adds 2%~5% activated carbon, 2h is stirred at 80 DEG C~85 DEG C, refilter, filter vacuum is concentrated, remove the water of wherein 80%.
In oil phase, other oils and fats is added by above-mentioned requirements, it is subsequently adding the blended emulsifier (wherein containing 34%Tween60 and 66%Span65) of 0.1% (weight), aqueous phase emulsifying after concentrating with vacuum again, homogenizing 0.5h (rotating speed 14000r/min), it is 0.02% (weight), potassium sorbate 0.1% (weight) by antioxidant TBHQ, sand milling is sheared dispersion 6h~8h add, continue homogenizing 1.5~2h.

Claims (10)

1. an Antilipemic health oil, it is characterised in that it is prepared from by the raw material of Chinese medicine medicine of following weight proportion,
2. Antilipemic health according to claim 1 oil, it is characterised in that it is prepared from by the raw material of Chinese medicine medicine of following weight proportion,
3. Antilipemic health according to claim 1 oil, it is characterised in that it is prepared from by the raw material of Chinese medicine medicine of following weight proportion,
4. the preparation method of the Antilipemic health oil described in claim 1, it is characterised in that step is as follows:
Step 1,
Chinese crude drug is pulverized, and adds salad oil, heat-insulation soaking 10-15 hour at 95 DEG C~105 DEG C, and then add water fried 2-5h, oil-water separation, and oil phase is standby,
Step 2,
Aqueous phase, adds the activated carbon of 2%~5%, at 85 DEG C~95 DEG C insulated and stirred 1h~2h, concentrates after filtration, and concentrated solution is standby,
Step 3,
In oil phase add Fructus Maydis oil, Oleum Arachidis hypogaeae semen, Oleum sesami, add emulsifying agent, and aqueous phase carries out emulsifying, homogenizing obtain the present invention Antilipemic health oil,
Wherein, the part by weight of four kinds of oils and fatss is as follows
5. preparation method according to claim 4, it is characterised in that
Wherein the Chinese crude drug in step 1 first through drying, chopping up, parch, then pulverize, 10~20 orders sieve, and the amount adding salad oil is medical material weight 1.5-2.5 times. Add 0.5-1.5 times that amount is medical material weight of water.
6. preparation method according to claim 4, it is characterised in that
The wherein concentration in step 2, selected from vacuum evaporation, steams the water of wherein 80%.
7. the preparation method of the Antilipemic health oil described in claim 1, it is characterised in that
Wherein the emulsifying agent in step 3 is selected from: the mixture of Span60 and Tween60, it may be necessary to add antioxidant or preservative.
8. preparation method according to claim 7, it is characterised in that
Wherein said antioxidant is selected from: the excellent precious TBHQ antioxidant in Guangzhou, makes consumption 0.02%, and adds the citric acid of 0.001%, and preservative is selected from: potassium sorbate 0.1%,
Wherein, the part by weight of four kinds of oils and fatss is as follows
9. preparation method according to claim 7, it is characterised in that the mixture of emulsifying agent Span60 and Tween60, wherein containing 34%Tween60 and 66%Span65.
10. preparation method according to claim 7, it is characterised in that step is as follows:
Chinese crude drug is through cleaning, dry, shred, pulverize, steaming stir-fry, pulverize then through pulverizer, sieve through 10~20 mesh sieve, add the soybean salad oil of 2 times of weight, at 95 DEG C~105 DEG C, 12h processed is soaked in insulation, be subsequently adding 1~1.5 times of deionized water, maintenance water is in slight boiling condition, uncovered fried 4h in bottom, filters through filter plant, by oil phase and aqueous phase stratification, making biphase separating in phase separator, oil phase cools down, and aqueous phase adds 2%~5% activated carbon, 2h is stirred at 80 DEG C~85 DEG C, refilter, filter vacuum is concentrated, remove the water of wherein 80%;
Oil phase adds other oils and fats, it is subsequently adding the blended emulsifier of 0.1%, it is wherein 34%Tween60 and 66%Span65 containing weight ratio, then aqueous phase emulsifying after concentrating with vacuum, homogenizing 0.5h, rotating speed 14000r/min,, by 0.02% antioxidant TBHQ, 0.1% potassium sorbate, sand milling is sheared dispersion 6h~8h and adds, continue homogenizing 1.5~2h, to obtain final product.
CN201610032010.2A 2016-01-19 2016-01-19 Lipid-reducing healthcare oil Pending CN105661542A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106753752A (en) * 2016-12-13 2017-05-31 青岛嘉瑞生物技术有限公司 A kind of health-care salicorne oil beneficial to hypotensive
CN108157530A (en) * 2018-01-19 2018-06-15 柳州市鱼峰区倪氏味之坊屏山店螺蛳粉休闲餐吧 A kind of nutrient and flavour salad oil
CN108175063A (en) * 2018-01-19 2018-06-19 柳州市鱼峰区倪氏味之坊屏山店螺蛳粉休闲餐吧 A kind of production method of instant banana flowers

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1298698A (en) * 2000-05-26 2001-06-13 湖南金键米业股份有限公司 Health-care oil for regulating blood fat
CN1416879A (en) * 2002-11-27 2003-05-14 天大药业(深圳)有限公司 Antilipemic Chinese medicine
CN1440804A (en) * 2003-03-31 2003-09-10 江西汇仁药业有限公司 Antilipemic Chinese medicine
CN101219175A (en) * 2007-01-09 2008-07-16 李青 Weight reducing essential oil
CN101292685A (en) * 2007-04-26 2008-10-29 赵凯 Health care edible oil
KR20090085876A (en) * 2008-02-05 2009-08-10 한상노 The extracts and fractions of hippophae rhamnoides l
CN104257839A (en) * 2014-10-17 2015-01-07 山东省中医药研究院 Traditional Chinese medicine composition with effects of reducing blood glucose and blood fat and protecting vascular endothelium and preparation method thereof
CN104256008A (en) * 2014-09-27 2015-01-07 山东吴氏恒康健康科技有限公司 Crataegus pinnatifida bunge and semen cassiae tea and preparation method thereof

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1298698A (en) * 2000-05-26 2001-06-13 湖南金键米业股份有限公司 Health-care oil for regulating blood fat
CN1416879A (en) * 2002-11-27 2003-05-14 天大药业(深圳)有限公司 Antilipemic Chinese medicine
CN1440804A (en) * 2003-03-31 2003-09-10 江西汇仁药业有限公司 Antilipemic Chinese medicine
CN101219175A (en) * 2007-01-09 2008-07-16 李青 Weight reducing essential oil
CN101292685A (en) * 2007-04-26 2008-10-29 赵凯 Health care edible oil
KR20090085876A (en) * 2008-02-05 2009-08-10 한상노 The extracts and fractions of hippophae rhamnoides l
CN104256008A (en) * 2014-09-27 2015-01-07 山东吴氏恒康健康科技有限公司 Crataegus pinnatifida bunge and semen cassiae tea and preparation method thereof
CN104257839A (en) * 2014-10-17 2015-01-07 山东省中医药研究院 Traditional Chinese medicine composition with effects of reducing blood glucose and blood fat and protecting vascular endothelium and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
宋光森等: "降脂营养保健油的研制", 《中国油脂》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106753752A (en) * 2016-12-13 2017-05-31 青岛嘉瑞生物技术有限公司 A kind of health-care salicorne oil beneficial to hypotensive
CN108157530A (en) * 2018-01-19 2018-06-15 柳州市鱼峰区倪氏味之坊屏山店螺蛳粉休闲餐吧 A kind of nutrient and flavour salad oil
CN108175063A (en) * 2018-01-19 2018-06-19 柳州市鱼峰区倪氏味之坊屏山店螺蛳粉休闲餐吧 A kind of production method of instant banana flowers

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Application publication date: 20160615