CN105535798A - 一种治疗泄泻的新型中药组合物及其制备方法 - Google Patents

一种治疗泄泻的新型中药组合物及其制备方法 Download PDF

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CN105535798A
CN105535798A CN201610086957.1A CN201610086957A CN105535798A CN 105535798 A CN105535798 A CN 105535798A CN 201610086957 A CN201610086957 A CN 201610086957A CN 105535798 A CN105535798 A CN 105535798A
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rhizoma
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夏瑜
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Chengdu Feilong Water Treatment Technology Research Institute Qingbaijiang First Branch
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Abstract

本发明属于中医药技术领域，目的是根据中医对泄泻的认识机理而提供的一种治疗泄泻的新型中药组合物，所述中药组合物的各个组分及其质量份比如下所示：泽泻10～20g、党参15～25g、车前子9～15g、附子（制）5～15g、白术3～16g、山药（炒）15～28g、茯苓10～16g、神曲6～15g、麦芽15～25g、陈皮3～12g、薏苡仁10～30g、鸡内金5～15g、黄芩3～12g、黄连1.5～3g、苍术（炒）3～10g、厚朴3～15g、藿香6～11g、佩兰6～12g、砂仁3～8g、草豆蔻3～7g、米壳3～6g、芡实米9～16g、金樱子9～16g、苦参5～10g、银柴胡5～10g、胡黄连6～13g；本发明提供的药物药效好见效快，是一个标本兼治的中药组方。

Description

一种治疗泄泻的新型中药组合物及其制备方法
技术领域
本发明涉及中医药技术领域，具体涉及一种治疗泄泻的新型中药组合物，特别是供泄泻患者使用的中药组合物及其制备方法的领域。
背景技术
医学界认为：泄泻指排便次数增多，粪质稀薄，甚则泻出如水。本病一年四季均可发生，但以夏秋季节多见。可见与急慢性肠炎、肠功能紊乱、结肠过敏或功能性腹泻等。其临床可分为急性腹泻和慢性腹泻。
那么，就如何找到一种可有效治疗泄泻的中药组合物，是我们目前应该要解决的问题。
发明内容
随着我国中医中药学的不断发展，在治疗泄泻上，人们逐渐意识到了中医治疗上述疾病的优点，且在治疗过程中毒副作用小、费用低等优势，针对现有西医治疗泄泻的现状，本发明的目的是在于提供一种治疗泄泻的新型中药组合物，以解决泄泻患者早日恢复健康的问题。该药物是以常见的中药为原料，具有见效快、疗效显著等特点，并可有效治疗上述泄泻一症。
为达到上述发明的目的，本发明所采用的技术方案为：提供一种治疗泄泻的新型中药组合物及其制备方法，其特征在于，所述中药组合物的各个组分及其质量份比如下所示：
泽泻10～20g、党参15～25g、车前子9～15g、附子（制）5～15g、白术3～16g、山药（炒）15～28g、茯苓10～16g、神曲6～15g、麦芽15～25g、陈皮3～12g、薏苡仁10～30g、鸡内金5～15g、黄芩3～12g、黄连1.5～3g、苍术（炒）3～10g、厚朴3～15g、藿香6～11g、佩兰6～12g、砂仁3～8g、草豆蔻3～7g、米壳3～6g、芡实米9～16g、金樱子9～16g、苦参5～10g、银柴胡5～10g、胡黄连6～13g。
一种治疗泄泻的新型中药组合物及其制备方法，其特征在于，所述中药组合物的各个组分及其质量份比如下所示：
泽泻12～17g、党参17～22g、车前子10～13g、附子（制）8～13g、白术8～14g、山药（炒）18～25g、茯苓11～14g、神曲8～13g、麦芽18～22g、陈皮6～11g、薏苡仁12～25g、鸡内金8～13g、黄芩6～11g、黄连1.5～2.5g、苍术（炒）5～9g、厚朴6～13g、藿香8～10g、佩兰8～11g、砂仁5～7g、草豆蔻4～6g、米壳4～5.5g、芡实米10～14g、金樱子10～14g、苦参6～9g、银柴胡6～9g、胡黄连7～12g。
一种治疗泄泻的新型中药组合物及其制备方法，其特征在于，所述“最佳方案”的中药组合物的各个组分及其质量份比如下所示：
泽泻15g、党参20g、车前子12g、附子（制）12g、白术12g、山药（炒）22g、茯苓13g、神曲12g、麦芽20g、陈皮10g、薏苡仁22g、鸡内金12g、黄芩10g、黄连2g、苍术（炒）8g、厚朴12g、藿香9g、佩兰10g、砂仁6g、草豆蔻5g、米壳5g、芡实米13g、金樱子13g、苦参8g、银柴胡8g、胡黄连11g。
一种治疗泄泻的新型中药组合物及其制备方法，其特征在于，所述方法包括如下步骤制备而成：
A、将上述原料中药分别拣去杂质和粉尘后，按照质量份比分别粉碎成粗粒状包煎；
B、将包好的原料中药放入冷开水中浸泡30分钟,然后再将浸泡好的药物和浸泡药物的澄清液一并放入煎药机内，注入过药36mm的冷开水进行第一次煎煮45分钟，滤取药液后，再次注入过药32mm的微温开水进行第二次煎煮40分钟，二次混合浓缩成50%的中药液1200毫升，袋装密封后备用。
一种治疗泄泻的新型中药组合物及其制备方法，其特征在于，所述服用方法为：将制备好的中药液分二天服用，早中晚各服一次，给药量200毫升/次，饭前服，服药3-6天，病获痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料，充分发挥各组分的药理功效：
泽泻，性味：甘、寒，具有利水，渗湿，泄热之功效，用于治疗小便不利、水肿胀满、呕吐、泻痢、痰饮、脚气、淋病、尿血；
党参，性味：味甘、性平，具有健脾补肺、益气生津之功效，用于治疗脾胃虚弱、食少便溏、四肢乏力、肺虚喘咳、气短自汗、气微两亏等症；
车前子，性味：味甘、性寒，具有清热利尿、渗湿通淋、明目、祛痰之功效，用于治疗水肿胀满、热淋涩痛、暑湿泄泻、目赤肿痛、痰热咳嗽；
附子（制），性味：辛甘、热，有毒，具有回阳救逆、补火助阳、散寒除湿之功效，用于治疗阴盛格阳、大汗亡阳、吐利厥逆、心腹冷痛、脾泄冷痢、脚气水肿、小儿慢惊、风寒湿痹、踒躄拘挛、阳萎、宫冷阴、疽疮漏及一切沉寒痼冷之疾；
白术，性味：味苦、甘、性温，具有健脾益气、燥湿利水、止汗、安胎之功效，用于治疗脾气虚弱、神疲乏力、食少少腹胀、大便溏薄、水饮内停、小便不利、水肿、痰饮眩晕、温痹酸痛、气虚自汗、胎动不安；
山药（炒），性味：甘、平，具有健脾、补肺、固肾、益精之功效，用于治疗脾虚泄泻、久痢、虚劳咳嗽、消渴、遗精、带下、小便频数；另具补脾养胃、生津益肺、补肾涩精之功效，用于脾虚食少、久泻不止、肺虚喘咳、肾虚遗精、带下、尿频、虚热消渴；
茯苓，性味：甘、淡、平，具有利水药、渗湿利尿药之功效，用于治疗小便不利、水肿胀满、痰饮咳逆、呕吐、脾虚食少、泄泻、心悸不安、失眠健忘、遗精白浊；
神曲，性味：甘、辛、温，具有消食和胃、消食调中之功效，用于治疗饮食停滞、胸痞腹胀、呕吐泻痢、产后瘀血腹痛、小儿腹大坚积；
麦芽，性味：甘、平，具有行气消食、健脾开胃、退乳消胀之功效，用于治疗食积不消、脘腹胀痛、脾虚食少、乳汗郁积、乳房胀痛、妇女断乳，生麦芽健脾和胃通乳，用于脾虚食少、乳汗郁积；
陈皮，性味：味辛、苦、性温，具有理气和中，燥湿化痰，利水通便之功效，用于治疗脾胃不和、脘腹胀痛、不思饮食、呕吐哕逆、痰湿阻肺、咳嗽痰多、胸膈满闷、头目眩晕、水肿、小便不利、大便秘结、乳痈疥癣、中鱼蟹毒、酒毒等；
薏苡仁，性味：甘淡、凉，具有健脾、补肺、清热、利湿之功效，用于治疗泄泻、湿痹、筋脉拘挛、屈伸不利、水肿、脚气、肺痿、肺痈、肠痈、淋浊、白带等；
鸡内金，性味：甘、平，具有消积滞、健脾胃之功效，用于治疗食积胀满、呕吐反胃、泻痢、疳积、消渴、遗溺、喉痹乳蛾、牙疳口疮；
黄芩，性味：味苦、性寒，具有清热泻火、燥湿解毒、止血、安胎之功效，用于治疗肺热咳嗽、热病高热神昏、肝火头痛、目赤肿痛、湿热黄疸、泻痢、热淋、吐衄血、崩漏、胎热不安、痈肿疔疮等症；
黄连，性味：苦、寒，具有清热燥湿、泻火解毒之功效，用于治疗湿热痞满、呕吐吞酸、泻痢、黄疸、高热神昏、心火亢盛、心烦不寐、血热吐衄、目赤、牙痛、消渴、痈肿疔疮，外治湿疹，湿疮，耳道流脓；
苍术（炒），性味：辛、苦、温，具有燥湿健脾、祛风散寒、明目之功效，用于治疗脘腹胀满、泄泻、水肿、风湿痹痛、风寒感冒、夜盲；
厚朴，性味：苦、辛、温，具有燥湿消痰、下气除满之功效，用于治疗湿阻中焦，脘腹胀满，食积气滞，腹胀便秘，痰饮喘咳；此外，七情郁结，痰气互阻，咽中如有物阻，咽之不下，吐之不出的梅核气证，亦可取本品燥湿消痰，下气宽中之效；
藿香，性味：辛、微温，具有芳香化浊、和中止呕、发表解暑之功效，用于治疗湿浊中阻、脘痞呕吐、暑湿表证、湿温初起、发热倦怠、胸闷不舒、寒湿闭暑、腹痛吐泻、鼻渊头痛；
佩兰，性味：味辛、性平，具有解暑化湿、辟秽和中之功效，用于治疗感受暑湿、寒热头痛、湿润内蕴、脘痞不饥、恶心呕吐、口中甜腻、消洵；
砂仁，性味：味辛、性温，具有化湿开胃、温脾止泻、理气安胎之功效，用于治疗湿浊中阻、脘痞不饥、脾胃虚寒、呕吐泄泻、妊娠恶阻、胎动不安；
草豆蔻，性味：味辛、性温，具有温中燥湿、行气健脾之功效，用于治疗寒湿阴滞脾胃之脘腹冷痛、痞满作胀、呕吐、泄泻、食谷不化、痰馀、脚气、阐疟、口臭；
米壳，性味：酸、涩、平，有毒，具有敛肺、涩肠、止痛之功效，用于治疗久咳、久泻、脱肛、脘腹疼痛；
芡实米，性味：甘、涩、性平，具有固肾涩精、补脾止泄之功效，用于治疗遗精、淋浊、带下、小便不禁、大便泄泻；
金樱子，性味：酸涩、平，具有固精、缩尿、涩肠、止带之功效，用于治疗滑精、滑精、遗尿、尿频、久泻、久痢、白浊、白带、崩漏、脱肛、子宫下垂；
苦参，性味：苦、寒，具有清热燥湿、杀虫、利尿之功效，用于治疗热痢、便血、黄疸尿闭、赤白带下、阴肿阴痒、湿疹、湿疮、皮肤瘙痒、疥癣麻风等症，外治滴虫性阴道炎；
银柴胡，性味：甘、性微寒，具有清虚热、除疳热之功效，用于治疗阴虚发热、骨蒸劳热、小儿疳积发热；
胡黄连，性味：味苦、性寒，具有退虚热、消疳热、清热燥湿、泻火解毒之功效，用于治疗阴虚骨蒸、潮热盗汗、小儿疳疾、湿热泻痢、黄疸、吐血、衄血、目赤肿痛、痈肿疮疡、痔疮肿毒。
本发明药物是基于中医治疗泄泻的辨病与辨证相结合的原则，从药理作用及作用机制认为：就泄泻一症，本发明所提供的药物中的各原料中药药效共奏，对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述泄泻的治疗而提出的一种中药配方，采用该配方制备的药物药效好，见效快，是一个标本兼治的中药组方，特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述：
实施例1：
一种治疗泄泻的新型中药组合物及其制备方法，所述中药组合物的各个组分及其质量份比如下所示：
泽泻15g、党参20g、车前子12g、附子（制）12g、白术12g、山药（炒）22g、茯苓13g、神曲12g、麦芽20g、陈皮10g、薏苡仁22g、鸡内金12g、黄芩10g、黄连2g、苍术（炒）8g、厚朴12g、藿香9g、佩兰10g、砂仁6g、草豆蔻5g、米壳5g、芡实米13g、金樱子13g、苦参8g、银柴胡8g、胡黄连11g。
实施例2：
一种治疗泄泻的新型中药组合物及其制备方法，所述中药组合物的各个组分及其质量份比如下所示：
泽泻17g、党参22g、车前子13g、附子（制）13g、白术14g、山药（炒）25g、茯苓14g、神曲13g、麦芽22g、陈皮11g、薏苡仁25g、鸡内金13g、黄芩11g、黄连2.5g、苍术（炒）9g、厚朴13g、藿香10g、佩兰11g、砂仁7g、草豆蔻6g、米壳5.5g、芡实米14g、金樱子14g、苦参9g、银柴胡9g、胡黄连12g。
实施例3：
一种治疗泄泻的新型中药组合物及其制备方法，所述中药组合物的各个组分及其质量份比如下所示：
泽泻15g、党参20g、车前子12g、附子（制）12g、白术12g、山药（炒）22g、茯苓13g、神曲12g、麦芽20g、陈皮10g、薏苡仁22g、鸡内金12g、黄芩10g、黄连2g、苍术（炒）8g、厚朴12g、藿香9g、佩兰10g、砂仁6g、草豆蔻5g、米壳5g、芡实米13g、金樱子13g、苦参8g、银柴胡8g、胡黄连11g。
典型病例：
经临床诊断治疗泄泻患者共115例，年龄为23岁以上的64例，只有51例为23岁以下。115例患者中痊愈的112例，显效3例，总有效率达100%。经治疗后，病获痊愈。

Claims (3)

1.一种治疗泄泻的新型中药组合物，其特征在于，所述中药组合物的各个组分及其质量份比如下所示：
泽泻10～20g、党参15～25g、车前子9～15g、附子（制）5～15g、白术3～16g、山药（炒）15～28g、茯苓10～16g、神曲6～15g、麦芽15～25g、陈皮3～12g、薏苡仁10～30g、鸡内金5～15g、黄芩3～12g、黄连1.5～3g、苍术（炒）3～10g、厚朴3～15g、藿香6～11g、佩兰6～12g、砂仁3～8g、草豆蔻3～7g、米壳3～6g、芡实米9～16g、金樱子9～16g、苦参5～10g、银柴胡5～10g、胡黄连6～13g。
2.根据权利要求1所述的治疗泄泻的新型中药组合物，其特征在于，所述中药组合物的各个组分及其质量份比如下所示：
泽泻12～17g、党参17～22g、车前子10～13g、附子（制）8～13g、白术8～14g、山药（炒）18～25g、茯苓11～14g、神曲8～13g、麦芽18～22g、陈皮6～11g、薏苡仁12～25g、鸡内金8～13g、黄芩6～11g、黄连1.5～2.5g、苍术（炒）5～9g、厚朴6～13g、藿香8～10g、佩兰8～11g、砂仁5～7g、草豆蔻4～6g、米壳4～5.5g、芡实米10～14g、金樱子10～14g、苦参6～9g、银柴胡6～9g、胡黄连7～12g。
3.根据权利要求1至2所述的治疗泄泻的新型中药组合物，其特征在于，所述中药组合物的各个组分及其质量份比如下所示：
泽泻15g、党参20g、车前子12g、附子（制）12g、白术12g、山药（炒）22g、茯苓13g、神曲12g、麦芽20g、陈皮10g、薏苡仁22g、鸡内金12g、黄芩10g、黄连2g、苍术（炒）8g、厚朴12g、藿香9g、佩兰10g、砂仁6g、草豆蔻5g、米壳5g、芡实米13g、金樱子13g、苦参8g、银柴胡8g、胡黄连11g。
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106166265A (zh) * 2016-10-01 2016-11-30 四川兴聚焦医药科技有限责任公司 一种治疗脾胃湿热型慢性胃炎的汤剂药物及其制备方法
CN106266920A (zh) * 2016-09-22 2017-01-04 四川兴聚焦医药科技有限责任公司 一种治疗湿热积滞类腹痛的中药组合物及其制备方法
CN106994175A (zh) * 2017-05-28 2017-08-01 吴娇宇 治疗小儿热泄泻的中药组合物
CN108721558A (zh) * 2018-08-20 2018-11-02 熊学荣 一种治疗婴幼儿消化不良的中药组合物及其制备方法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106266920A (zh) * 2016-09-22 2017-01-04 四川兴聚焦医药科技有限责任公司 一种治疗湿热积滞类腹痛的中药组合物及其制备方法
CN106166265A (zh) * 2016-10-01 2016-11-30 四川兴聚焦医药科技有限责任公司 一种治疗脾胃湿热型慢性胃炎的汤剂药物及其制备方法
CN106994175A (zh) * 2017-05-28 2017-08-01 吴娇宇 治疗小儿热泄泻的中药组合物
CN108721558A (zh) * 2018-08-20 2018-11-02 熊学荣 一种治疗婴幼儿消化不良的中药组合物及其制备方法

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