CN105535717A - Traditional Chinese medicine composition for preventing and treating postpartum hemorrhage - Google Patents
Traditional Chinese medicine composition for preventing and treating postpartum hemorrhage Download PDFInfo
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Classifications
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Abstract
The invention relates to a traditional Chinese medicine composition for preventing and treating postpartum hemorrhage, which is prepared from the following raw medicines in parts by weight: 15-35 parts of angelica, 10-30 parts of thistle, 10-25 parts of rhizoma sparganii, 10-25 parts of purslane, 10-30 parts of costus root, 10-25 parts of folium artemisiae argyi, 5-20 parts of safflower, 5-25 parts of prepared rehmannia root, 10-20 parts of evodia rutaecarpa, 10-35 parts of cockscomb, 5-25 parts of cacumen biotae and 5-20 parts of thunberg fritillary bulb. The traditional Chinese medicine composition has the effects of alleviating pain and arresting bleeding, dredging collaterals and activating blood circulation, replenishing the vital essence and removing heat as well as benefiting qi and nourishing blood. The traditional Chinese medicine composition is free of toxic or side effect and obvious in effect when used for preventing and treating postpartum hemorrhage.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, in particular to a kind of Chinese medicine composition of prevention and therapy postpartum hemorrhage.
Background technology
After delivery of baby, 24 hours per vaginam bleeding capacity are more than 500ml person, are called postpartum hemorrhage.This is the common severe complications of obstetrics, is one of obstetrics' danger disease, should payes attention to especially.Main cause is uterine atony, coagulation disorders etc., clinical manifestation for birth canal hemorrhage anxious and measure many, or lasting small amount bleeding, severe one can be suffered a shock.Simultaneously can weak with dizziness, drowsiness, inappetence, diarrhoea, edema, galactostasis, alopecia, fear of cold etc.The high risk factor of postpartum hemorrhage comprises uterine inertia, placenta previa, placental adherence, soft birth canal injury, coagulation disorders and childbirth options etc., and the factor wherein had the greatest impact is uterine inertia.Any uterus muscle fiber that affects normally contracts again and the factor of contractile function, all can cause uterine contractions fatigue.Placenta factors is also cause another major reason of postpartum hemorrhage, repeatedly artificial abortion or childbirth, operation on uterus history, previously has placental adherence history person, and the probability that placental adherence or placenta previa occur is larger.
Chinese medicine thinks that postpartum hemorrhage is the disease such as " massive postpartum vaginal bleeding ", " puerperal blood faints ", see the earliest " General Treatise on the Cause and Symptoms of Diseases blood in puerperal transports vexed time ", its etiology and pathogenesis is divided into, 1. the deficiency of vital energy: puerpera's ferritic is weak, or because of consumption gas of losing blood when producing, or because of stages of labor long, overfatigue, suffers tremendous loss in strength or resources, the deficiency of vital energy debility of CHONG and REN meridians, blood loses and has under one's command, then cause hemorrhage; 2. blood stasis: during product, blood room is just opened, cold-evil takes advantage of a weak point in opponent's defence into born of the same parents, fights mutually with blood, blood-stasis internal-depression, or afterbirth remains, and impact punching is appointed, escape of blood from meridian, so that haemophilia; 3. maternal infuries: during product, practise midwifery is improper, or force of labor is excessively strong, and progress of labor is too fast, or fetus is excessive, so that injury of birth canal, and venation is damaged, outside blood oozing from the body openings or subcuta neous tissue arteries and veins, then makes blood go out incessantly.
Summary of the invention
The invention provides a kind of Chinese medicine composition of prevention and therapy postpartum hemorrhage, this Chinese medicine composition have analgesic hemostatic, dredging collateral is invigorated blood circulation, replenishing YIN and removing heat, benefiting qi and nourishing blood effect, for prevention and therapy postpartum hemorrhage, have no side effect, Be very effective.
Concrete, one aspect of the present invention provides a kind of Chinese medicine composition of prevention and therapy postpartum hemorrhage, is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 15-35 part, Radix Cirsii Japonici 10-30 part, Rhizoma Sparganii 10-25 part, Herba Portulacae 10-25 part, Radix Aucklandiae 10-30 part, Folium Artemisiae Argyi 10-25 part, Flos Carthami 5-20 part, Radix Rehmanniae Preparata 5-25 part, Fructus Evodiae 10-20 part, Flos Celosiae Cristatae 10-35 part, Cacumen Platycladi 5-25 part, Bulbus Fritillariae Thunbergii 5-20 part.
In the embodiment that the present invention one is concrete, the Chinese medicine composition of described a kind of prevention and therapy postpartum hemorrhage is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 20-35 part, Radix Cirsii Japonici 10-25 part, Rhizoma Sparganii 15-25 part, Herba Portulacae 10-20 part, Radix Aucklandiae 10-25 part, Folium Artemisiae Argyi 15-25 part, Flos Carthami 15-20 part, Radix Rehmanniae Preparata 10-25 part, Fructus Evodiae 10-15 part, Flos Celosiae Cristatae 10-20 part, Cacumen Platycladi 5-20 part, Bulbus Fritillariae Thunbergii 15-20 part.
In the embodiment that the present invention one is concrete, the Chinese medicine composition of described a kind of prevention and therapy postpartum hemorrhage is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 15-25 part, Radix Cirsii Japonici 20-30 part, Rhizoma Sparganii 15-25 part, Herba Portulacae 10-20 part, Radix Aucklandiae 20-30 part, Folium Artemisiae Argyi 15-25 part, Flos Carthami 5-15 part, Radix Rehmanniae Preparata 10-25 part, Fructus Evodiae 15-20 part, Flos Celosiae Cristatae 20-35 part, Cacumen Platycladi 15-25 part, Bulbus Fritillariae Thunbergii 5-15 part.
In the embodiment that the present invention one is concrete, the Chinese medicine composition of described a kind of prevention and therapy postpartum hemorrhage is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 27 parts, Radix Cirsii Japonici 23 parts, Rhizoma Sparganii 16 parts, Herba Portulacae 19 parts, the Radix Aucklandiae 28 parts, Folium Artemisiae Argyi 14 parts, 14 parts, Flos Carthami, 20 parts, Radix Rehmanniae Preparata, Fructus Evodiae 17 parts, Flos Celosiae Cristatae 32 parts, Cacumen Platycladi 21 parts, Bulbus Fritillariae Thunbergii 15 parts.
In the embodiment that the present invention one is concrete, the Chinese medicine composition of described a kind of prevention and therapy postpartum hemorrhage is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 30 parts, Radix Cirsii Japonici 25 parts, Rhizoma Sparganii 15 parts, Herba Portulacae 20 parts, the Radix Aucklandiae 15 parts, Folium Artemisiae Argyi 20 parts, 10 parts, Flos Carthami, 20 parts, Radix Rehmanniae Preparata, Fructus Evodiae 15 parts, Flos Celosiae Cristatae 30 parts, Cacumen Platycladi 20 parts, Bulbus Fritillariae Thunbergii 15 parts.
In the embodiment that the present invention one is concrete, the Chinese medicine composition of described a kind of prevention and therapy postpartum hemorrhage is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 20 parts, Radix Cirsii Japonici 15 parts, Rhizoma Sparganii 20 parts, Herba Portulacae 15 parts, the Radix Aucklandiae 25 parts, Folium Artemisiae Argyi 15 parts, 18 parts, Flos Carthami, 23 parts, Radix Rehmanniae Preparata, Fructus Evodiae 12 parts, Flos Celosiae Cristatae 26 parts, Cacumen Platycladi 17 parts, Bulbus Fritillariae Thunbergii 13 parts.
The present invention provides a kind of preparation method of Chinese medicine composition of prevention and therapy postpartum hemorrhage on the other hand, and it is characterized in that, the preparation method of this pharmaceutical composition comprises the following steps:
(1) Radix Cirsii Japonici, Rhizoma Sparganii, the Radix Aucklandiae, Flos Carthami, Flos Celosiae Cristatae, Cacumen Platycladi add soak by water 2-3 time accounting for gross weight 8-15 times amount, each 1.5-2 hour, collecting decoction, add the aqueous solution that step (1) obtains again, filter, relative density when filtrate is concentrated into 80 DEG C is the extractum (I) of 1.15-1.25;
(2) Radix Angelicae Sinensis, Herba Portulacae, Folium Artemisiae Argyi, Radix Rehmanniae Preparata, Fructus Evodiae, Bulbus Fritillariae Thunbergii are added account for gross weight 8-15 times amount 85% alcoholic solution in extract 2-3 time, each 2-3 hour, filter, merging filtrate, placement is spent the night, reclaim ethanol, relative density when filtrate being concentrated into 60 DEG C is the extractum (II) of 1.15-1.25;
(3) in step (1), the mixing of (2) gained extractum, dry, stir, to obtain final product.
In a concrete embodiment of the present invention, wherein add the soak by water 3 times accounting for gross weight 10 times amount in step (1), each 1.5 hours; Account in step (2) in the alcoholic solution of 85% of gross weight 10 times amount and extract 2 times, each 3 hours.
The Chinese medicine composition of prevention and therapy postpartum hemorrhage of the present invention, also can prepare according to the conventional method of the field of Chinese medicines, comprises soak by water, by each crude drug pulverize etc.The conventional method of Chinese medicine preparation can be adopted to be prepared into any traditional oral preparation.Described oral formulations is capsule, pill, powder, tablet, granule, decoction, soft capsule.
Pharmaceutical composition of the present invention, based on the dialectical prescription of tcm theory, this Chinese medicine composition has analgesic hemostatic, dredging collateral is invigorated blood circulation, replenishing YIN and removing heat, benefiting qi and nourishing blood effect, for prevention and therapy postpartum hemorrhage, have no side effect, Be very effective.
Detailed description of the invention
Embodiment 1:
The Chinese medicine composition of prevention and therapy postpartum hemorrhage is made up of the crude drug of following weight portion: a Radix Angelicae Sinensis 27g, Radix Cirsii Japonici 23g, Rhizoma Sparganii 16g, Herba Portulacae 19g, Radix Aucklandiae 28g, Folium Artemisiae Argyi 14g, Flos Carthami 14g, Radix Rehmanniae Preparata 20g, Fructus Evodiae 17g, Flos Celosiae Cristatae 32g, Cacumen Platycladi 21g, Bulbus Fritillariae Thunbergii 15g;
Each crude drug is dry at 45 DEG C, be cooled to room temperature, pulverize state, and mix homogeneously, load snap fit capsule, to obtain final product.
Embodiment 2:
The Chinese medicine composition of prevention and therapy postpartum hemorrhage is made up of the crude drug of following weight portion: a Radix Angelicae Sinensis 27g, Radix Cirsii Japonici 23g, Rhizoma Sparganii 16g, Herba Portulacae 19g, Radix Aucklandiae 28g, Folium Artemisiae Argyi 14g, Flos Carthami 14g, Radix Rehmanniae Preparata 20g, Fructus Evodiae 17g, Flos Celosiae Cristatae 32g, Cacumen Platycladi 21g, Bulbus Fritillariae Thunbergii 15g;
Take said medicine by formula ratio, be added to the water, boil, slow fire boiling 30 minutes, filter, filtering residue adds water again, slow fire boiling 30 minutes, merge twice medicinal liquid, to obtain final product.
Embodiment 3:
The Chinese medicine composition of prevention and therapy postpartum hemorrhage is made up of the crude drug of following weight portion: a Radix Angelicae Sinensis 27g, Radix Cirsii Japonici 23g, Rhizoma Sparganii 16g, Herba Portulacae 19g, Radix Aucklandiae 28g, Folium Artemisiae Argyi 14g, Flos Carthami 14g, Radix Rehmanniae Preparata 20g, Fructus Evodiae 17g, Flos Celosiae Cristatae 32g, Cacumen Platycladi 21g, Bulbus Fritillariae Thunbergii 15g;
Preparation method comprises the following steps:
(1) Radix Cirsii Japonici, Rhizoma Sparganii, the Radix Aucklandiae, Flos Carthami, Flos Celosiae Cristatae, Cacumen Platycladi add the soak by water 3 times accounting for gross weight 10 times amount, each 2 hours, collecting decoction, add the aqueous solution that step (1) obtains again, filter, relative density when filtrate is concentrated into 80 DEG C is the extractum (I) of 1.15-1.25;
(2) Radix Angelicae Sinensis, Herba Portulacae, Folium Artemisiae Argyi, Radix Rehmanniae Preparata, Fructus Evodiae, Bulbus Fritillariae Thunbergii are added account for gross weight 10 times amount 85% alcoholic solution in extract 3 times, each 2 hours, filter, merging filtrate, placement is spent the night, reclaim ethanol, relative density when filtrate being concentrated into 60 DEG C is the extractum (II) of 1.15-1.25;
(3) in step (1), the mixing of (2) gained extractum, dry, stir, incapsulate and get final product.
Embodiment 4:
The Chinese medicine composition of prevention and therapy postpartum hemorrhage is made up of the crude drug of following weight portion: a Radix Angelicae Sinensis 30g, Radix Cirsii Japonici 25g, Rhizoma Sparganii 15g, Herba Portulacae 20g, Radix Aucklandiae 15g, Folium Artemisiae Argyi 20g, Flos Carthami 10g, Radix Rehmanniae Preparata 20g, Fructus Evodiae 15g, Flos Celosiae Cristatae 30g, Cacumen Platycladi 20g, Bulbus Fritillariae Thunbergii 15g;
Take said medicine by formula ratio, be added to the water, boil, slow fire boiling 30 minutes, filter, filtering residue adds water again, slow fire boiling 30 minutes, merge twice medicinal liquid, to obtain final product.
Embodiment 5:
The Chinese medicine composition of prevention and therapy postpartum hemorrhage is made up of the crude drug of following weight portion: a Radix Angelicae Sinensis 20g, Radix Cirsii Japonici 15g, Rhizoma Sparganii 20g, Herba Portulacae 15g, Radix Aucklandiae 25g, Folium Artemisiae Argyi 15g, Flos Carthami 18g, Radix Rehmanniae Preparata 23g, Fructus Evodiae 12g, Flos Celosiae Cristatae 26g, Cacumen Platycladi 17g, Bulbus Fritillariae Thunbergii 13g;
Take said medicine by formula ratio, be added to the water, boil, slow fire boiling 30 minutes, filter, filtering residue adds water again, slow fire boiling 30 minutes, merge twice medicinal liquid, to obtain final product.
Comparative example 1:
The Chinese medicine composition of prevention and therapy postpartum hemorrhage is made up of the crude drug of following weight portion: a Radix Angelicae Sinensis 27g, Herba Portulacae 19g, Radix Aucklandiae 28g, Folium Artemisiae Argyi 14g, Flos Carthami 14g, Radix Rehmanniae Preparata 20g, Fructus Evodiae 17g, Flos Celosiae Cristatae 32g, Cacumen Platycladi 21g, Bulbus Fritillariae Thunbergii 15g;
Take said medicine by formula ratio, be added to the water, boil, slow fire boiling 30 minutes, filter, filtering residue adds water again, slow fire boiling 30 minutes, merge twice medicinal liquid, to obtain final product.
Comparative example 2:
The Chinese medicine composition of prevention and therapy postpartum hemorrhage is made up of the crude drug of following weight portion: a Radix Angelicae Sinensis 27g, Radix Cirsii Japonici 23g, Rhizoma Sparganii 16g, Herba Portulacae 19g, Radix Aucklandiae 28g, Folium Artemisiae Argyi 14g, Flos Carthami 14g, Radix Rehmanniae Preparata 20g, Fructus Evodiae 17g, Flos Celosiae Cristatae 32g;
Each crude drug is dry at 45 DEG C, be cooled to room temperature, pulverize state, and mix homogeneously, load snap fit capsule, to obtain final product.
Embodiment 6: Chinese medicine composition of the present invention is on mice docking bleeding time and the impact of clotting time
1, experimental animal: regular grade kunming mice 80, male and female are more than half, body weight 23-27g, are divided into 8 groups at random, often organize 10.
2, test drug and dosage regimen:
Blank group: isometric(al) normal saline gavage every day 1 time, continuous gavage 6 days; Positive controls: Fuxuekang granules (the accurate word Z20026089 of traditional Chinese medicines, Guangxi Guixi Pharmaceutical Co., Ltd), becomes the suspension of 60% by water allotment concentration, for subsequent use, by dosage gavage every day 1 time of 8.4g/kg, and successive administration 6 days; Chinese medicine composition group of the present invention: the Chinese medicine composition that the embodiment of the present invention 2 is obtained, every day gavage 1 time, successive administration 6 days; Comparative example 1 Chinese medicine composition group: the Chinese medicine composition that comparative example 1 is obtained, every day gavage 1 time, successive administration 6 days.
3, test method:
(1) mensuration in mice docking bleeding time: get 4 groups of mices and carry out administration by corresponding dosage regimen, mice last gastric infusion was anaesthetized with pentobarbital sodium after 1 hour, in order to cutting cross-section for Mouse Tail-tip 1/3 place, timing is started when blood overflows voluntarily, drop of blood is sucked once every 30s filter paper, naturally stop (when filter paper is inhaled depletion of blood) until hemorrhage, the statistics docking bleeding time.
(2) mensuration of clotting time of mice: get 4 groups of mices and carry out administration by corresponding dosage regimen, mice last gastric infusion inserts mice side corner of the eyes ball rear vein beard with disposable quantitative blood vessel after 1 hour and gets blood, be full of to capillary glass tube, set level, alternately a bit of from two ends breaking glass capillary tube every 30s, check with or without the appearance of blood clotting silk, fracture from the other end and verify, there is the time of blood clotting silk in average two ends, is clotting time.
4, result of the test is in table 1.
Table 1 Chinese medicine composition of the present invention is on mice docking bleeding time and the impact of clotting time
| Group | Docking bleeding time (min) | Clotting time (min) |
| Blank group | 20.58±2.15 | 4.25±1.12 |
| Positive controls | 16.75±3.98 * | 3.18±1.35 * |
| Chinese medicine composition group of the present invention | 15.35±1.56 * | 2.98±1.13 * |
| Comparative example 1 Chinese medicine composition group | 17.38±1.26 | 3.68±1.46 |
*P＜0.05
Data in table 1 show, Chinese medicine composition of the present invention can reduce mice docking bleeding time and clotting time, and the medicine that the effect of the Chinese medicine composition of the embodiment of the present invention 2 preparation will be prepared significantly better than comparative example 1.
Embodiment 7: Chinese medicine of the present invention is on the impact of mice amount of bleeding after medicine stream
1, experimental animal:
Cleaning grade Balb/C mice, is provided by Shandong University's Experimental Animal Center, 10 weeks ages of Mus, body weight (22 ± 2) g, the non-copulation of female mice, and male mice proves there is fertility.Be placed in room temperature 24 DEG C, in the ultra-clean animal breeding cabinet of relative humidity 60% ~ 65%, give 12h illumination, 12h darkroom, freely drink water and ingest.Male and female mice in 2:1 ratio in afternoon every day 5:00 mate, m seq observes the cloudy bolt of mice, finds that cloudy bolt day was for gestation the 1st day.Pregnant Mus is divided at random negative control group, positive controls, pharmaceutical composition group of the present invention, often organizes each 10.
2, test drug and dosage regimen:
Negative control group from mouse pregnancy the 6th day, gavage mifepristone (0.88mgkg
-1d
-1)+distilled water, the continuous gavage of mifepristone 3 days, the continuous gavage of distilled water 7 days; Positive controls from mouse pregnancy the 6th day, gavage mifepristone (0.88mgkg
-1d
-1)+Angong Zhixue Granules aqueous solution (500mgkg
-1d
-1), the continuous gavage of mifepristone 3 days, the continuous gavage of Angong Zhixue Granules aqueous solution 7 days; Chinese medicine composition group of the present invention from mouse pregnancy the 6th day, gavage mifepristone (0.88mgkg
-1d
-1capsule 's content (500mgkg prepared by the)+embodiment of the present invention 3
-1d
-1), the continuous gavage of mifepristone 3 days, the continuous gavage of Chinese medicine composition of the present invention 7 days.
3, test method
From drug treating the 1st day, insert the quantitative cotton balls of 20g in mouse vagina, every day is changed, and is placed in airtight EP pipe, 4 DEG C of preservations, and improvement alkali haematin method detects Mouse Uterus amount of bleeding, the results are shown in Table 2.
Table 2 medicine of the present invention is on the impact of mice amount of bleeding after medicine stream
| Group | Negative control group | Positive controls | Chinese medicine composition group of the present invention |
| Average bleeding μ l | 28.31 | 22.12 | 18.56 |
Data in table 2 show, Chinese medicine composition of the present invention obviously can reduce Mouse Uterus amount of bleeding after medicine stream.
Embodiment 8: clinical postpartum hemorrhage amount test
Selection of clinical Patients with 300 Cases, wherein age 25-40 year, Cesarean esction 150 example, vaginal delivery 150 example, is divided into three groups at random, treatment by Chinese herbs group of the present invention, matched group and blank group, often organizes 100 examples.
The treatment by Chinese herbs component puerperium of the present invention gives capsule 2 prepared by the embodiment of the present invention 1 immediately, and injects oxytocin 10U; Matched group divides the puerperium to give the capsule 2 of comparative example 2 preparation immediately, and injects oxytocin 10U; Blank group only injects oxytocin 10U.
Observe and record 2h, 24h amount of bleeding in puerperal, the results are shown in Table 3.
Table 3 medicine of the present invention is on the impact of postpartum hemorrhage amount
| 2h average bleeding in puerperal (ml) | 24h average bleeding in puerperal (ml) | |
| Treatment by Chinese herbs group of the present invention | 150±23.2 | 190±24.1 |
| Matched group | 178±24.8 | 228±25.4 |
| Blank group | 233±26.7 | 305±34.1 |
Can be drawn by the data of table 3, Chinese medicine of the present invention obviously can reduce postpartum hemorrhage amount.In whole experimentation all there is not any untoward reaction in all cases.
Claims (8)
1. a Chinese medicine composition for prevention and therapy postpartum hemorrhage, is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 15-35 part, Radix Cirsii Japonici 10-30 part, Rhizoma Sparganii 10-25 part, Herba Portulacae 10-25 part, Radix Aucklandiae 10-30 part, Folium Artemisiae Argyi 10-25 part, Flos Carthami 5-20 part, Radix Rehmanniae Preparata 5-25 part, Fructus Evodiae 10-20 part, Flos Celosiae Cristatae 10-35 part, Cacumen Platycladi 5-25 part, Bulbus Fritillariae Thunbergii 5-20 part.
2. the Chinese medicine composition of a kind of prevention and therapy postpartum hemorrhage according to claim 1, is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 20-35 part, Radix Cirsii Japonici 10-25 part, Rhizoma Sparganii 15-25 part, Herba Portulacae 10-20 part, Radix Aucklandiae 10-25 part, Folium Artemisiae Argyi 15-25 part, Flos Carthami 15-20 part, Radix Rehmanniae Preparata 10-25 part, Fructus Evodiae 10-15 part, Flos Celosiae Cristatae 10-20 part, Cacumen Platycladi 5-20 part, Bulbus Fritillariae Thunbergii 15-20 part.
3. the Chinese medicine composition of a kind of prevention and therapy postpartum hemorrhage according to claim 1, is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 15-25 part, Radix Cirsii Japonici 20-30 part, Rhizoma Sparganii 15-25 part, Herba Portulacae 10-20 part, Radix Aucklandiae 20-30 part, Folium Artemisiae Argyi 15-25 part, Flos Carthami 5-15 part, Radix Rehmanniae Preparata 10-25 part, Fructus Evodiae 15-20 part, Flos Celosiae Cristatae 20-35 part, Cacumen Platycladi 15-25 part, Bulbus Fritillariae Thunbergii 5-15 part.
4. the Chinese medicine composition of a kind of prevention and therapy postpartum hemorrhage according to claim 1, is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 27 parts, Radix Cirsii Japonici 23 parts, Rhizoma Sparganii 16 parts, Herba Portulacae 19 parts, the Radix Aucklandiae 28 parts, Folium Artemisiae Argyi 14 parts, 14 parts, Flos Carthami, 20 parts, Radix Rehmanniae Preparata, Fructus Evodiae 17 parts, Flos Celosiae Cristatae 32 parts, Cacumen Platycladi 21 parts, Bulbus Fritillariae Thunbergii 15 parts.
5. the Chinese medicine composition of a kind of prevention and therapy postpartum hemorrhage according to claim 1, is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 30 parts, Radix Cirsii Japonici 25 parts, Rhizoma Sparganii 15 parts, Herba Portulacae 20 parts, the Radix Aucklandiae 15 parts, Folium Artemisiae Argyi 20 parts, 10 parts, Flos Carthami, 20 parts, Radix Rehmanniae Preparata, Fructus Evodiae 15 parts, Flos Celosiae Cristatae 30 parts, Cacumen Platycladi 20 parts, Bulbus Fritillariae Thunbergii 15 parts.
6. the Chinese medicine composition of a kind of prevention and therapy postpartum hemorrhage according to claim 1, is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 20 parts, Radix Cirsii Japonici 15 parts, Rhizoma Sparganii 20 parts, Herba Portulacae 15 parts, the Radix Aucklandiae 25 parts, Folium Artemisiae Argyi 15 parts, 18 parts, Flos Carthami, 23 parts, Radix Rehmanniae Preparata, Fructus Evodiae 12 parts, Flos Celosiae Cristatae 26 parts, Cacumen Platycladi 17 parts, Bulbus Fritillariae Thunbergii 13 parts.
7. the Chinese medicine composition of a kind of prevention and therapy postpartum hemorrhage described in claim 1-6, is characterized in that, adopts the conventional method of Chinese medicine preparation to be prepared into any traditional oral preparation.
8. the Chinese medicine composition of a kind of prevention and therapy postpartum hemorrhage according to claim 7, is characterized in that, described oral formulations is capsule, pill, powder, tablet, granule, decoction, soft capsule.
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|---|---|---|---|---|
| CN103908593A (en) * | 2014-04-09 | 2014-07-09 | 黄绪峰 | Compound medicine for preventing and treating postpartum hemorrhage |
| CN103919968A (en) * | 2014-04-09 | 2014-07-16 | 黄绪峰 | Compound medicine for preventing and treating postpartum hemorrhage |
| CN105148235A (en) * | 2015-09-25 | 2015-12-16 | 汤华淑 | Traditional Chinese medicine combination treating postpartum hemorrhage |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103908593A (en) * | 2014-04-09 | 2014-07-09 | 黄绪峰 | Compound medicine for preventing and treating postpartum hemorrhage |
| CN103919968A (en) * | 2014-04-09 | 2014-07-16 | 黄绪峰 | Compound medicine for preventing and treating postpartum hemorrhage |
| CN105148235A (en) * | 2015-09-25 | 2015-12-16 | 汤华淑 | Traditional Chinese medicine combination treating postpartum hemorrhage |
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Application publication date: 20160504 |