CN105535680A - Patent medicine for coping with acute asthma episode in emergency treatment - Google Patents

Patent medicine for coping with acute asthma episode in emergency treatment Download PDF

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CN105535680A
CN105535680A CN201511029780.3A CN201511029780A CN105535680A CN 105535680 A CN105535680 A CN 105535680A CN 201511029780 A CN201511029780 A CN 201511029780A CN 105535680 A CN105535680 A CN 105535680A
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parts
herba
patent medicine
radix
rhizoma
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刘宝龙
张茂全
高鲁
杨浩
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刘宝龙
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964—Anemarrhena
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994—Coix (Job's tears)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention relates to a patent medicine for coping with an acute asthma episode in emergency treatment. The patent medicine is prepared from, by weight, 40-60 parts of herba pteridis multifidae, 40-60 parts of herba taraxaci, 25-35 parts of climbing groundsel herb, 25-35 parts of rhizoma anemarrhenae, 20-30 parts of dysosma versipellis, 10-20 parts of herba ephedra, 10-20 parts of common andrographis herb, 10-20 parts of mulberry twigs, 3-8 parts of silkworm feces, 3-8 parts of borneol and 3-8 parts of coix seeds. According to the patent medicine for coping with the acute asthma episode in emergency treatment, the ministerial drugs can clear heat and remove toxicity, eliminate phlegm and remove stasis, promote secretion of saliva or body fluid and moisten dryness and eliminate bronchia and lung inflammations; the monarch drug is strong in drug efficacy and can clear heat and remove toxicity, eliminate phlegm and removing stasis, promote secretion of saliva or body fluid and moisten dryness and quickly eliminate the bronchia and lung inflammations; the ministerial drugs are mainly used for enhancing the drug property of the monarch drug; in the formula, all the drugs achieve the compatibility, the monarch drug and the ministerial drugs cooperative with each other to remove the inflammations, the adjuvant drugs and the conductant drugs jointly achieve the assisting effect to relieve the toxicity and violence of the medicine, and the patent medicine is used for treating the symptoms such as a cough, a pant, dyspnea, chest distress, expectoration, expiratory dyspnea with paroxysmal wheezing rale and the like which are caused by bronchial asthma.

Description

A kind of patent medicine of emergency treatment reply asthma in acute attack
Technical field
The present invention relates to a kind of patent medicine for the treatment of asthma, particularly a kind of patent medicine of emergency treatment reply asthma in acute attack.
Background technology
Bronchial asthma, usually also known as asthma.Clinical manifestation is: patient respiratory difficulty, hurriedly, often itches with nasopharynx, dry cough, uncomfortable in chest, cyanosis of the face and lips, opening mouth and lifting shoulder due to dyspnea, and breast has toot sound, volume antiperspirant, difficult sleeping, recurrent exerbation, continue at every turn a few minutes, several hours even several days not etc., be many with night and morning.Severe one is with increased heart rate, paradoxical pulse, breast abdomen dyskinesis and cyanosis phenomenon.The cause of disease and the pathogenesis of asthma imperfectly understand, Therapeutic Method and medicine different, and determined curative effect, the medicine particularly can cured lacks still very much.In the last few years, foreign study adopted aminophylline, cut sieve treatment bronchial asthma, and the curative effect just taken is better, then patient body strengthens Western medicine Drug resistance, to the chronic disease of this frequent anti-slander, then need to strengthen dose, to reach therapeutic effect, and the Drug resistance due to patient had, even if strengthen dose to be also difficult to find out effect, meanwhile, the toxic and side effects of these medicines is larger, complication is many, makes numerous often ill weak patient be difficult to take; In addition, Western medicine is cured the symptoms, not the disease usually, and the duration of drug effect is short.Also there is patient's Chinese medicine and western medicine to hold concurrently clothes clinically, but still there is the drawback of the comparatively large and effect relative mistake of dose.Emergency department mostly is the acute breakthrough symptoms of reply, with quick Contact Surfaces symptom for principle, therefore crude drug preparation absorbs the patent medicine of onset fast, and, the slow inherent shortcoming of onset complicated to Traditional Chinese medicine decocting for the emergency treatment overcoming Precipitated acute asthma has important progress and creationary meaning.
Summary of the invention
The technical problem to be solved in the present invention is the above-mentioned defect how overcoming prior art, provides a kind of emergency treatment to tackle the patent medicine of asthma in acute attack.
For solving the problems of the technologies described above, the patent medicine of this emergency treatment reply asthma in acute attack, it is characterized in that: this patent medicine is prepared according to shown weight ratio scope by following component, Herba Pteridis Multifidae 40 ~ 60 parts, Herba Taraxaci 40 ~ 60 parts, Herba Senecionis Scandentis 25 ~ 35 parts, the Rhizoma Anemarrhenae 25 ~ 35 parts, Radix et Rhizoma Dysosmatis 20 ~ 30 parts, 10 ~ 20 parts, Herba Ephedrae, Herba Andrographis 10 ~ 20 parts, Ramulus Mori 10 ~ 20 parts, Bombyx mori L. 3 ~ 8 parts, Borneolum Syntheticum 3 ~ 8 parts, Semen Coicis 3 ~ 8 parts, the preparation method of described patent medicine is, by Herba Pteridis Multifidae, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae, Herba Andrographis, Ramulus Mori, Bombyx mori L., Borneolum Syntheticum, after Semen Coicis weighs by described proportioning, by the Herba Pteridis Multifidae that 1/3rd amounts are got, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae decocting liquid makes diluent, the Herba Pteridis Multifidae of other 2/3rds amounts, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae mixes with all the other components, the water soaking adding mixture 50 times amount decocts three times, about each half an hour, the decocting liquid merging three times filters, and be concentrated into paste, add Ramulus Mori liquid diluent again to stir and make soft material, dry under 40 ~ 60 DEG C of conditions, be ground into fine powder, ethanol with 80% does binding agent and makes 20 order granules, the magnesium stearate of 1% of granular mass is added after granulate, after dry, pulverizing makes powder, with vinegar fried dry in this powder, load in snuffing bottle, the occupation mode of described patent medicine is, first stage, first snuffing 50mg, and then interval sucks 25 milligrams in 5 minutes, and maximum sucting number of per stage is 10 times, and the second stage suction again at least 2 hours of rear interval, must not use more than 5 stages every day.
As optimum ratio scope, described patent medicine is prepared according to shown weight ratio scope by following component, Herba Pteridis Multifidae 49 ~ 51 parts, Herba Taraxaci 49 ~ 51 parts, Herba Senecionis Scandentis 29 ~ 31 parts, the Rhizoma Anemarrhenae 29 ~ 31 parts, Radix et Rhizoma Dysosmatis 29 ~ 31 parts, 14 ~ 16 parts, Herba Ephedrae, Herba Andrographis 14 ~ 16 parts, Ramulus Mori 14 ~ 16 parts, Bombyx mori L. 5 ~ 7 parts, Borneolum Syntheticum 5 ~ 7 parts, Semen Coicis 5 ~ 7 parts.
As optimum ratio, described patent medicine is prepared according to shown weight ratio by following component, Herba Pteridis Multifidae 60 parts, Herba Taraxaci 40 parts, Herba Senecionis Scandentis 35 parts, the Rhizoma Anemarrhenae 25 parts, Radix et Rhizoma Dysosmatis 30 parts, 10 parts, Herba Ephedrae, Herba Andrographis 20 parts, Ramulus Mori 10 parts, Bombyx mori L. 8 parts, Borneolum Syntheticum 3 parts, Semen Coicis 8 parts.
As optimum ratio, described patent medicine is prepared according to shown weight ratio by following component, Herba Pteridis Multifidae 40 parts, Herba Taraxaci 60 parts, Herba Senecionis Scandentis 25 parts, the Rhizoma Anemarrhenae 35 parts, Radix et Rhizoma Dysosmatis 20 parts, 20 parts, Herba Ephedrae, Herba Andrographis 10 parts, Ramulus Mori 20 parts, Bombyx mori L. 3 parts, Borneolum Syntheticum 8 parts, Semen Coicis 3 parts.
As further optimum ratio, described patent medicine is prepared according to shown weight ratio by following component, Herba Pteridis Multifidae 51 parts, Herba Taraxaci 49 parts, Herba Senecionis Scandentis 31 parts, the Rhizoma Anemarrhenae 29 parts, Radix et Rhizoma Dysosmatis 31 parts, 14 parts, Herba Ephedrae, Herba Andrographis 16 parts, Ramulus Mori 14 parts, Bombyx mori L. 7 parts, Borneolum Syntheticum 5 parts, Semen Coicis 7 parts.
As further optimum ratio, described patent medicine is prepared according to shown weight ratio by following component, Herba Pteridis Multifidae 49 parts, Herba Taraxaci 51 parts, Herba Senecionis Scandentis 29 parts, the Rhizoma Anemarrhenae 31 parts, Radix et Rhizoma Dysosmatis 29 parts, 16 parts, Herba Ephedrae, Herba Andrographis 146 parts, Ramulus Mori 16 parts, Bombyx mori L. 5 parts, Borneolum Syntheticum 7 parts, Semen Coicis 5 parts.
As optimum proportioning, described patent medicine is prepared according to shown weight ratio by following component, Herba Pteridis Multifidae 50 parts, Herba Taraxaci 50 parts, Herba Senecionis Scandentis 30 parts, the Rhizoma Anemarrhenae 30 parts, Radix et Rhizoma Dysosmatis 30 parts, 15 parts, Herba Ephedrae, Herba Andrographis 15 parts, Ramulus Mori 15 parts, Bombyx mori L. 6 parts, Borneolum Syntheticum 6 parts, Semen Coicis 6 parts.
Pharmacology analysis
Herba Pteridis Multifidae: lightly seasoned, micro-hardship, cool in nature; Return large intestine, the heart, Liver Channel; Clearing away heat-damp and promoting diuresis, removing toxic substances dysentery relieving, cooling blood for hemostasis.For dysentery, gastroenteritis, hepatitis, urinary system infection, cat fever, laryngopharynx swelling and pain, leucorrhea, metrorrhagia, pesticide intoxication; Traumatic hemorrhage is controlled in external, burn and scald.
Herba Taraxaci: bitter in the mouth, sweet, cold in nature; Return liver, stomach warp; Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome, for furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Herba Senecionis Scandentis: bitter in the mouth, pungent, cold in nature; Return heat-clearing and toxic substances removing, improving acuity of vision and removing nebula, killing parasites for relieving itching, for influenza, upper respiratory tract infection, pneumonia, acute tonsillitis etc.
The Rhizoma Anemarrhenae: bitter in the mouth, sweet, cold in nature; Return lung, stomach, kidney channel; Clearing away heat-fire, promotes the production of body fluid and moisturizes, and for fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Radix et Rhizoma Dysosmatis: bitter in the mouth, pungent, warm in nature; Heat-clearing and toxic substances removing, dissipating phlegm and resolving masses, eliminating phlegm for diminishing swelling, for carbuncle furuncle, scrofula, laryngopharynx swelling and pain, traumatic injury, venom.
Herba Ephedrae: acrid in the mouth, micro-hardship, warm in nature; Diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.For anemofrigid cold, uncomfortable in chestly to breath with cough, edema due to wind pathogen edema, bronchial asthma.
Herba Andrographis: bitter in the mouth, cold in nature.GUIXIN, lung, large intestine, urinary bladder channel.Heat-clearing and toxic substances removing, pathogenic fire purging, dampness, clinical in anemopyretic cold, epidemic febrile disease is generated heat, cough due to lung-heat, pertussis, lung abscess, laryngopharynx swelling and pain, jaundice due to damp-heat, stranguria, erysipelas, skin infection carbuncle, eczema, venom etc.
Ramulus Mori: mildly bitter flavor, property is put down; Enter lung, kidney two warp; Wind-damp dispelling, the meridian dredging, row aqueous vapor, main air pain of dampness syndrome, apoplexy and hemiplegia, edema beriberi, human body pruritus due to wind pathogen.
Bombyx mori L.: sweet in the mouth, pungent, warm in nature; Return liver, spleen, stomach warp; Expelling wind and removing dampness, regulating the function of the stomach to resolve the turbidity, promoting blood circulation to restore menstrual flow, main air pain of dampness syndrome, limbs are unsuccessful, rubella pruritus, convulsion of vomiting and diarrhoea, amenorrhea, metrorrhagia.
Borneolum Syntheticum: acrid in the mouth, hardship, cool in nature; GUIXIN, lung meridian; To have one's ideas straightened out refreshment, heat radiation pain relieving, improving eyesight removing nebula, for apoplexy, calentura coma, deafness with qi stagnation, sore throat, aphtha, carbuncle, hemorrhoid, the diseases such as enterobiasis.
Semen Coicis: sweet, light, cool; Return spleen, stomach, lung meridian; Spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, row is dense in heat clearing away.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana.
The patent medicine of a kind of emergency treatment of the present invention reply asthma in acute attack is with Herba Pteridis Multifidae, Herba Taraxaci, Herba Senecionis Scandentis 2, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae for monarch drug, and the efficacy of a drug is vigorous, heat-clearing and toxic substances removing, expectorant powder junction, promotes the production of body fluid and moisturizes, and eliminates bronchus and pneumonia fast; With Herba Andrographis, Ramulus Mori, Bombyx mori L. for ministerial drug, be mainly used in the property of medicine increasing monarch drug, there is invigorating spleen and kidney, helping inspiration to relieve asthma simultaneously, eliminate the symptom of hypopnea; With Borneolum Syntheticum, Semen Coicis for adjuvant blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, invigorating the spleen and replenishing QI, nourishing kidney lung moistening, air making-up and spleen enlivening, for maintenance protection and the vital base and primordial QI consolidating of respiratory system; All medicine compatibilities in side, the monarch and his subjects pull together, eliminate the inflammation, and assistant makes auxiliary altogether, the toxicity of cushion and strong, be used for the treatment of cough that bronchial asthma causes, pant, dyspnea, uncomfortable in chest, expectoration, the symptom such as the ictal expiratory dyspnea with wheezing sound.
Detailed description of the invention
Embodiment 1: by Herba Pteridis Multifidae 60g, Herba Taraxaci 40g, Herba Senecionis Scandentis 35g, Rhizoma Anemarrhenae 25g, Radix et Rhizoma Dysosmatis 30g, Herba Ephedrae 10g, Herba Andrographis 20g, Ramulus Mori 10g, Bombyx mori L. 8g, Borneolum Syntheticum 3g, the proportioning of Semen Coicis 8g takes each component, by Herba Pteridis Multifidae, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae, Herba Andrographis, Ramulus Mori, Bombyx mori L., Borneolum Syntheticum, after Semen Coicis weighs by described proportioning, by the Herba Pteridis Multifidae that 1/3rd amounts are got, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae decocting liquid makes diluent, the Herba Pteridis Multifidae of other 2/3rds amounts, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae mixes with all the other components, the water soaking adding mixture 50 times amount decocts three times, about each half an hour, the decocting liquid merging three times filters, and be concentrated into paste, add Ramulus Mori liquid diluent again to stir and make soft material, dry under 40 ~ 60 DEG C of conditions, be ground into fine powder, the ethanol with 80% does binding agent and makes 20 order granules, adds the magnesium stearate of 1% of granular mass after granulate, after dry, pulverizing makes powder, with vinegar fried dry in this powder, load in snuffing bottle, obtain the patent medicine A of this emergency treatment reply asthma in acute attack, the occupation mode of described patent medicine is, first stage, first snuffing 50mg, and then interval sucks 25 milligrams in 5 minutes, and maximum sucting number of per stage is 10 times, and the second stage suction again at least 2 hours of rear interval, must not use more than 5 stages every day.
Embodiment 2: by Herba Pteridis Multifidae 40g, Herba Taraxaci 60g, Herba Senecionis Scandentis 25g, Rhizoma Anemarrhenae 35g, Radix et Rhizoma Dysosmatis 20g, Herba Ephedrae 20g, Herba Andrographis 10g, Ramulus Mori 20g, Bombyx mori L. 3g, Borneolum Syntheticum 8g, the proportioning of Semen Coicis 3g takes each component, just Herba Pteridis Multifidae, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae, Herba Andrographis, Ramulus Mori, Bombyx mori L., Borneolum Syntheticum, after Semen Coicis weighs by described proportioning, by the Herba Pteridis Multifidae that 1/3rd amounts are got, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae decocting liquid makes diluent, the Herba Pteridis Multifidae of other 2/3rds amounts, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae mixes with all the other components, the water soaking adding mixture 50 times amount decocts three times, about each half an hour, the decocting liquid merging three times filters, and be concentrated into paste, add Ramulus Mori liquid diluent again to stir and make soft material, dry under 40 ~ 60 DEG C of conditions, be ground into fine powder, the ethanol with 80% does binding agent and makes 20 order granules, adds the magnesium stearate of 1% of granular mass after granulate, after dry, pulverizing makes powder, with vinegar fried dry in this powder, load in snuffing bottle, obtain the patent medicine B of this emergency treatment reply asthma in acute attack, the occupation mode of described patent medicine is, first stage, first snuffing 50mg, and then interval sucks 25 milligrams in 5 minutes, and maximum sucting number of per stage is 10 times, and the second stage suction again at least 2 hours of rear interval, must not use more than 5 stages every day.
Embodiment 3: by Herba Pteridis Multifidae 51g, Herba Taraxaci 49g, Herba Senecionis Scandentis 31g, Rhizoma Anemarrhenae 29g, Radix et Rhizoma Dysosmatis 31g, Herba Ephedrae 14g, Herba Andrographis 16g, Ramulus Mori 14g, Bombyx mori L. 7g, Borneolum Syntheticum 5g, the proportioning of Semen Coicis 7g takes each component, by Herba Pteridis Multifidae, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae, Herba Andrographis, Ramulus Mori, Bombyx mori L., Borneolum Syntheticum, after Semen Coicis weighs by described proportioning, by the Herba Pteridis Multifidae that 1/3rd amounts are got, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae decocting liquid makes diluent, the Herba Pteridis Multifidae of other 2/3rds amounts, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae mixes with all the other components, the water soaking adding mixture 50 times amount decocts three times, about each half an hour, the decocting liquid merging three times filters, and be concentrated into paste, add Ramulus Mori liquid diluent again to stir and make soft material, dry under 40 ~ 60 DEG C of conditions, be ground into fine powder, the ethanol with 80% does binding agent and makes 20 order granules, adds the magnesium stearate of 1% of granular mass after granulate, after dry, pulverizing makes powder, with vinegar fried dry in this powder, load in snuffing bottle, obtain the patent medicine C of this emergency treatment reply asthma in acute attack, the occupation mode of described patent medicine is, first stage, first snuffing 50mg, and then interval sucks 25 milligrams in 5 minutes, and maximum sucting number of per stage is 10 times, and the second stage suction again at least 2 hours of rear interval, must not use more than 5 stages every day.。
Embodiment 4: by Herba Pteridis Multifidae 49g, Herba Taraxaci 51g, Herba Senecionis Scandentis 29g, Rhizoma Anemarrhenae 31g, Radix et Rhizoma Dysosmatis 29g, Herba Ephedrae 16g, Herba Andrographis 146g, Ramulus Mori 16g, Bombyx mori L. 5g, Borneolum Syntheticum 7g, the proportioning of Semen Coicis 5g takes each component, by Herba Pteridis Multifidae, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae, Herba Andrographis, Ramulus Mori, Bombyx mori L., Borneolum Syntheticum, after Semen Coicis weighs by described proportioning, by the Herba Pteridis Multifidae that 1/3rd amounts are got, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae decocting liquid makes diluent, the Herba Pteridis Multifidae of other 2/3rds amounts, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae mixes with all the other components, the water soaking adding mixture 50 times amount decocts three times, about each half an hour, the decocting liquid merging three times filters, and be concentrated into paste, add Ramulus Mori liquid diluent again to stir and make soft material, dry under 40 ~ 60 DEG C of conditions, be ground into fine powder, the ethanol with 80% does binding agent and makes 20 order granules, adds the magnesium stearate of 1% of granular mass after granulate, after dry, pulverizing makes powder, with vinegar fried dry in this powder, load in snuffing bottle, obtain the patent medicine D of this emergency treatment reply asthma in acute attack, the occupation mode of described patent medicine is, first stage, first snuffing 50mg, and then interval sucks 25 milligrams in 5 minutes, and maximum sucting number of per stage is 10 times, and the second stage suction again at least 2 hours of rear interval, must not use more than 5 stages every day.
Embodiment 5: by Herba Pteridis Multifidae 50g, Herba Taraxaci 50g, Herba Senecionis Scandentis 30g, Rhizoma Anemarrhenae 30g, Radix et Rhizoma Dysosmatis 30g, Herba Ephedrae 15g, Herba Andrographis 15g, Ramulus Mori 15g, Bombyx mori L. 6g, Borneolum Syntheticum 6g, the proportioning of Semen Coicis 6g takes each component, by Herba Pteridis Multifidae, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae, Herba Andrographis, Ramulus Mori, Bombyx mori L., Borneolum Syntheticum, after Semen Coicis weighs by described proportioning, by the Herba Pteridis Multifidae that 1/3rd amounts are got, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae decocting liquid makes diluent, the Herba Pteridis Multifidae of other 2/3rds amounts, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae mixes with all the other components, the water soaking adding mixture 50 times amount decocts three times, about each half an hour, the decocting liquid merging three times filters, and be concentrated into paste, add Ramulus Mori liquid diluent again to stir and make soft material, dry under 40 ~ 60 DEG C of conditions, be ground into fine powder, the ethanol with 80% does binding agent and makes 20 order granules, adds the magnesium stearate of 1% of granular mass after granulate, after dry, pulverizing makes powder, with vinegar fried dry in this powder, load in snuffing bottle, obtain the patent medicine E of this emergency treatment reply asthma in acute attack, the occupation mode of described patent medicine is, first stage, first snuffing 50mg, and then interval sucks 25 milligrams in 5 minutes, and maximum sucting number of per stage is 10 times, and the second stage suction again at least 2 hours of rear interval, must not use more than 5 stages every day.
In above-described embodiment, embodiment 5 is preferred embodiment.
Continue user clinical data
(1) case: clinical observation treatment is carried out to 300 routine Bronchial Asthmas.Wherein male 200 example, women 100 example, between 25 to 67 years old ages, 41 years old mean age, the course of disease 2 to 10 years, average 4.3 years.
(2) Therapeutic Method: patent medicine coated tablet E every day of this emergency treatment reply asthma in acute attack prepared by oral embodiment 5 three times, each two panels.Calculate treatment time according to conditions of patients weight, patients with mild takes about 20 days, and severe case serve on 90 days and can fully recover.
(3) criterion: healing-symptom all disappears; Main Physico-chemical tests index is normally; Effective-symptomatology is eliminated or cardinal symptom is eliminated, and Physico-chemical tests index is normal; Effectively-cardinal symptom disappears substantially, and main Physico-chemical tests index makes moderate progress; Invalid-main Physico-chemical tests index is front unchanged with treatment.
(4) therapeutic effect: clinical cure 240 example, effective 30 examples, effective 20 examples, invalid 10 examples, all cases all have no adverse reaction.
(5) curative effect is summed up: clinical time 4 to 5 years, curative effect 1 month effectively, the course for the treatment of general patient 4 months, symptom disappears substantially, and patient with severe symptoms's 6 months diseases disappear, and within 8 months, symptom all disappears.Effective percentage 96.67%, cure rate 80.00%.
Above-mentioned embodiment is intended to illustrate that the present invention can be professional and technical personnel in the field and realizes or use; modifying to above-mentioned embodiment will be apparent for those skilled in the art; therefore the present invention includes but be not limited to above-mentioned embodiment; any these claims or description of meeting describes; meet and principle disclosed herein and novelty, the method for inventive features, technique, product, all fall within protection scope of the present invention.

Claims (7)

1. the patent medicine of an emergency treatment reply asthma in acute attack, it is characterized in that: this patent medicine is prepared according to shown weight ratio scope by following component, Herba Pteridis Multifidae 40 ~ 60 parts, Herba Taraxaci 40 ~ 60 parts, Herba Senecionis Scandentis 25 ~ 35 parts, the Rhizoma Anemarrhenae 25 ~ 35 parts, Radix et Rhizoma Dysosmatis 20 ~ 30 parts, 10 ~ 20 parts, Herba Ephedrae, Herba Andrographis 10 ~ 20 parts, Ramulus Mori 10 ~ 20 parts, Bombyx mori L. 3 ~ 8 parts, Borneolum Syntheticum 3 ~ 8 parts, Semen Coicis 3 ~ 8 parts, the preparation method of described patent medicine is, by Herba Pteridis Multifidae, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae, Herba Andrographis, Ramulus Mori, Bombyx mori L., Borneolum Syntheticum, after Semen Coicis weighs by described proportioning, by the Herba Pteridis Multifidae that 1/3rd amounts are got, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae decocting liquid makes diluent, the Herba Pteridis Multifidae of other 2/3rds amounts, Herba Taraxaci, Herba Senecionis Scandentis, the Rhizoma Anemarrhenae, Radix et Rhizoma Dysosmatis, Herba Ephedrae mixes with all the other components, the water soaking adding mixture 50 times amount decocts three times, about each half an hour, the decocting liquid merging three times filters, and be concentrated into paste, add Ramulus Mori liquid diluent again to stir and make soft material, dry under 40 ~ 60 DEG C of conditions, be ground into fine powder, ethanol with 80% does binding agent and makes 20 order granules, the magnesium stearate of 1% of granular mass is added after granulate, after dry, pulverizing makes powder, with vinegar fried dry in this powder, load in snuffing bottle, the occupation mode of described patent medicine is, first stage, first snuffing 50mg, and then interval sucks 25 milligrams in 5 minutes, and maximum sucting number of per stage is 10 times, and the second stage suction again at least 2 hours of rear interval, must not use more than 5 stages every day.
2. the patent medicine of emergency treatment reply asthma in acute attack according to claim 1, it is characterized in that: described patent medicine is prepared according to shown weight ratio scope by following component, Herba Pteridis Multifidae 49 ~ 51 parts, Herba Taraxaci 49 ~ 51 parts, Herba Senecionis Scandentis 29 ~ 31 parts, the Rhizoma Anemarrhenae 29 ~ 31 parts, Radix et Rhizoma Dysosmatis 29 ~ 31 parts, 14 ~ 16 parts, Herba Ephedrae, Herba Andrographis 14 ~ 16 parts, Ramulus Mori 14 ~ 16 parts, Bombyx mori L. 5 ~ 7 parts, Borneolum Syntheticum 5 ~ 7 parts, Semen Coicis 5 ~ 7 parts.
3. the patent medicine of emergency treatment reply asthma in acute attack according to claim 1, it is characterized in that: described patent medicine is prepared according to shown weight ratio by following component, Herba Pteridis Multifidae 60 parts, Herba Taraxaci 40 parts, Herba Senecionis Scandentis 35 parts, the Rhizoma Anemarrhenae 25 parts, Radix et Rhizoma Dysosmatis 30 parts, 10 parts, Herba Ephedrae, Herba Andrographis 20 parts, Ramulus Mori 10 parts, Bombyx mori L. 8 parts, Borneolum Syntheticum 3 parts, Semen Coicis 8 parts.
4. the patent medicine of emergency treatment reply asthma in acute attack according to claim 1, it is characterized in that: described patent medicine is prepared according to shown weight ratio by following component, Herba Pteridis Multifidae 40 parts, Herba Taraxaci 60 parts, Herba Senecionis Scandentis 25 parts, the Rhizoma Anemarrhenae 35 parts, Radix et Rhizoma Dysosmatis 20 parts, 20 parts, Herba Ephedrae, Herba Andrographis 10 parts, Ramulus Mori 20 parts, Bombyx mori L. 3 parts, Borneolum Syntheticum 8 parts, Semen Coicis 3 parts.
5. the patent medicine of emergency treatment reply asthma in acute attack according to claim 2, it is characterized in that: described patent medicine is prepared according to shown weight ratio by following component, Herba Pteridis Multifidae 51 parts, Herba Taraxaci 49 parts, Herba Senecionis Scandentis 31 parts, the Rhizoma Anemarrhenae 29 parts, Radix et Rhizoma Dysosmatis 31 parts, 14 parts, Herba Ephedrae, Herba Andrographis 16 parts, Ramulus Mori 14 parts, Bombyx mori L. 7 parts, Borneolum Syntheticum 5 parts, Semen Coicis 7 parts.
6. the patent medicine of emergency treatment reply asthma in acute attack according to claim 2, it is characterized in that: described patent medicine is prepared according to shown weight ratio by following component, Herba Pteridis Multifidae 49 parts, Herba Taraxaci 51 parts, Herba Senecionis Scandentis 29 parts, the Rhizoma Anemarrhenae 31 parts, Radix et Rhizoma Dysosmatis 29 parts, 16 parts, Herba Ephedrae, Herba Andrographis 146 parts, Ramulus Mori 16 parts, Bombyx mori L. 5 parts, Borneolum Syntheticum 7 parts, Semen Coicis 5 parts.
7. the patent medicine of emergency treatment reply asthma in acute attack according to claim 2, it is characterized in that: described patent medicine is prepared according to shown weight ratio by following component, Herba Pteridis Multifidae 50 parts, Herba Taraxaci 50 parts, Herba Senecionis Scandentis 30 parts, the Rhizoma Anemarrhenae 30 parts, Radix et Rhizoma Dysosmatis 30 parts, 15 parts, Herba Ephedrae, Herba Andrographis 15 parts, Ramulus Mori 15 parts, Bombyx mori L. 6 parts, Borneolum Syntheticum 6 parts, Semen Coicis 6 parts.
CN201511029780.3A 2015-12-31 2015-12-31 Patent medicine for coping with acute asthma episode in emergency treatment Pending CN105535680A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103830636A (en) * 2014-01-06 2014-06-04 崔磊 Pharmaceutical composition for treating bronchitis and asthma

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103830636A (en) * 2014-01-06 2014-06-04 崔磊 Pharmaceutical composition for treating bronchitis and asthma

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Application publication date: 20160504