CN105498049B - Medical injector with ratchet-type plunger - Google Patents

Medical injector with ratchet-type plunger Download PDF

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Publication number
CN105498049B
CN105498049B CN201610042183.2A CN201610042183A CN105498049B CN 105498049 B CN105498049 B CN 105498049B CN 201610042183 A CN201610042183 A CN 201610042183A CN 105498049 B CN105498049 B CN 105498049B
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CN
China
Prior art keywords
plunger
ontology
actuator
medical injector
activator portion
Prior art date
Application number
CN201610042183.2A
Other languages
Chinese (zh)
Other versions
CN105498049A (en
Inventor
R·克罗嫩贝格
Original Assignee
贝克顿·迪金森公司
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Application filed by 贝克顿·迪金森公司 filed Critical 贝克顿·迪金森公司
Priority to CN201180070446.6A priority Critical patent/CN103501835B/en
Priority to CN201610042183.2A priority patent/CN105498049B/en
Publication of CN105498049A publication Critical patent/CN105498049A/en
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Publication of CN105498049B publication Critical patent/CN105498049B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501Means for blocking or restricting the movement of the rod or piston
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525Dosing
    • A61M5/31526Dosing by means of stepwise axial movements, e.g. ratchet mechanisms or detents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31535Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/3155Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159Dose expelling manners
    • A61M5/31593Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • A61M5/31595Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3125Details specific display means, e.g. to indicate dose setting

Abstract

A kind of medical injector belongs to medical instruments field, and the medical injector includes ontology and plunger, which there is distal end and proximal end, the plunger to be movably disposed in ontology.Plunger includes the multiple ratchets spaced apart arranged along its length.The selectively moved plug of plunger, to distribute medicament from the medical injector.Medical injector also includes:Protractor is arranged in ontology, to engagement pistons, to allow plunger to be distally moved and prevent plunger from being moved to nearside substantially;Actuator has bonding part, allows actuator mobile to nearside relative to plunger with engagement pistons and prevents actuator to be distally moved relative to plunger substantially;And rotatable parts, for making bonding part be moved to nearside relative to plunger and ontology.Medical injector using the present invention can make plunger controllably advance with the matched part of minimum number.

Description

Medical injector with ratchet-type plunger

The present invention is that international filing date is March 17, international application no PCT/US2011/000493, China in 2011 National application number be 201180070446.6, it is entitled " with ratchet-type plunger medical injector " patent of invention Shen Divisional application please.

Technical field

The present invention relates to packaged type medical injector plungers, it is more particularly related to the medical injection of ratchet-type Device plunger.

Background technology

Medical injector is well known in the art, these medical injectors include syringe and pen type injection Device.Medical injector typically comprises plunger, which is used for making one or more plugs during injection when conveying medicament Son advances.Although it is known in the art that syringe plunger is equipped with tooth or other feature, to prevent in initial injection It retraction later and reuses, syringe plunger is activated typically via the direct application of straight line force.Dosage size is column Fill in the direct function of displacement.Being controlled to the straight-line displacement of plunger will be difficult, thus cause to be difficult to control dosage Size.

About pen type injector, it is equipped with leading screw or rotary type plunger, the leading screw or rotary type plunger pass through a series of machineries It connects and is mechanically coupled on dosage setting button or other actuators.Typical pen type injector mechanism is considerably complicated, and And include multiple matched parts.In order to cost-effective and easy to use, desirably, most by the quantity of working part Smallization.

Invention content

Correspondingly, it is an aspect of the invention to provide a kind of plunger for medical injector, minimum number can be used Matched part so that the plunger is controllably advanced.

The above-mentioned and/or other aspects of the present invention are realized, the medical injector also by a kind of medical injector is provided Including ontology and plunger, which there is distal end and proximal end, the plunger to be movably disposed in ontology.Plunger packet Include the multiple ratchets spaced apart arranged along its length.The selectively moved plug of plunger, to be distributed from the medical injector Medicament.Medical injector also includes:Protractor is arranged in ontology, to engagement pistons, to allow plunger to be distally moved, And prevent plunger from being moved to nearside substantially;Actuator has bonding part, allows actuator relative to column with engagement pistons It fills in mobile to nearside and prevents actuator to be distally moved relative to plunger substantially;And rotatable parts, it is used for relative to column Plug and ontology make bonding part be moved to nearside.When actuator is moved proximally to preparation state relative to ontology, one or More ratchets cross bonding part, so that actuator is moved relative to plunger to nearside.In actuator relative to ontology from standard When standby state is distally moved, actuator engages one or more ratchets, and plunger is made to be distally moved relative to protractor, with So that plug is distally moved and distributes medicament from medical injector.

The above-mentioned and/or other aspects of the present invention are realized, the medical injector also by a kind of medical injector is provided Including ontology and plunger, which there is distal end and proximal end, the plunger to be movably disposed in ontology.Plunger packet Include the multiple ratchets spaced apart arranged along its length.The selectively moved plug of plunger, to distribute medicament from medical injector. Medical injector also includes protractor, which is arranged in ontology, to engagement pistons, to allow plunger distad to move It moves and prevents plunger from being moved to nearside substantially.Medical injector also comprises actuation means, which is used for activating doctor With instrument, there is actuation means engagement device, the engagement device to be used for engagement pistons, with allow actuation means relative to plunger to Nearside is mobile and prevents actuation means to be distally moved relative to plunger substantially.It is filled in addition, medical injector includes rotation It sets, which is used for making engagement device move to nearside relative to plunger and ontology.Actuation means relative to ontology to When nearside is moved to preparation state, one or more ratchets cross engagement device so that actuation means relative to plunger to close It moves side.When actuation means are distally moved relative to ontology from preparation state, actuation means engage one or more spine Tooth makes plunger be distally moved relative to protractor, so that plug is distally moved and distributes medicament from medical injector.

The above-mentioned and/or other aspects of present invention reality also by a kind of method from medical injector injection medicament of offer Existing, which there is ontology, the ontology to have distally and proximally end.This method includes following operation:Allow plunger Relative to being distally moved for ontology, and prevent plunger from being moved to nearside relative to ontology substantially;And allow actuator phase To nearside movement and actuator is prevented to be distally moved relative to plunger substantially plunger.This method also includes following behaviour Make:Rotatable parts are rotated, actuator is moved proximally to preparation state relative to ontology, thus make actuator relative to Plunger is moved to nearside;And be distally moved actuator from preparation state relative to ontology, thus engagement pistons, and make Plunger is distally moved relative to ontology, and distributes medicament from medical injector.

The other and/or other aspects and advantage of the present invention will be described partly in the de-scription, and will be partly by readding It reads to be described in detail and more obvious, or can be understood by being put into practice to the present invention.

Description of the drawings

Above and/or other aspect of each embodiment detailed further below, of the invention is carried out by connection with figures Will be more obvious with advantage and it be more prone to be recognized, in the drawings:

Fig. 1 is the stereogram of the medical injector of one embodiment according to the invention;

Fig. 2 is the stereogram of the plunger used for the syringe of Fig. 1;

Fig. 3 is the partial cross sectional view obtained along the line 3-3 of Fig. 2;

Fig. 4-6 is body portion sectional view, shows the operation of the medical injector of Fig. 1;

Fig. 7 and 8 is stereogram, respectively illustrates the two kinds of rocking bars used for the syringe of Fig. 1;

Fig. 9-11 is body portion sectional view, shows one embodiment according to the invention of the rocking bar using Fig. 7 The operation of medical injector;

Figure 12 and 13 is body portion sectional view, shows the multi link formula rocking bar of one embodiment according to the invention It uses;

Figure 14 is the dose counter used for one embodiment of the present of invention;

Figure 15 is the partial perspective view of the pivotable formula actuator used for the plunger of Fig. 2;

Figure 16 and 17 is body portion sectional view, shows the use of the pivotable formula actuator of Figure 15;

Figure 18 is the sectional view according to the medical injector of another embodiment of the present invention;

Figure 19 is the stereogram of one embodiment of the second part of the actuator of the medical injector of Figure 18;

Figure 20 is the phantom of the medical injector of Figure 18;

Figure 21 and 22 shows some optional embodiments of the groove of the second part of Figure 19;

Figure 23 is the stereogram of another embodiment of the second part of the actuator of the medical injector of Figure 18;

Figure 24 is the stereogram of the ontology of the medical injector of Figure 18;

Figure 25 is the stereogram of another embodiment of the second part of the actuator of the medical injector of Figure 18;

Figure 26 is the partial perspective view of the medical injector of Figure 18, which has the second part of Figure 25;

Figure 27 shows another embodiment of the groove of the second part of Figure 19;

Figure 28 is the stereogram according to the medical injector of another embodiment of the present invention;

Figure 29 is the stereogram of the actuator of the medical injector of Figure 28 and one embodiment of rocking bar;

Figure 30 and 31 is the stereogram of the ontology of the medical injector of Figure 28;

Figure 32 and 33 is the stereogram of the knob of the medical injector of Figure 28;And

Figure 34 is the phantom for limiting rib, and it is more than available amount which, which is used for preventing dosage setting value,.

Specific implementation mode

Now with detailed reference to each embodiment of the present invention, the example of these embodiments is shown in the accompanying drawings, wherein phase The reference numeral answered refers to corresponding element from beginning to end.The embodiments described herein is subject to example to the present invention by referring to accompanying drawing Show, rather than the present invention is limited.As will be understood by those skilled in the art, such as above and below, bottom and The term at top etc is relativity, to help to illustrate, rather than it is restrictive.

With reference to attached drawing, medical injector 10 is shown, which is equipped with the plunger 12 that can add ratchet. As the skilled person will recognize, medical injector 10 can have various forms, including syringe or pen type Injector.Embodiment according to the invention, medical injector 10 are particularly well-suited for applying at least one fixed dosage, and It is suitable for applying a series of fixed dosages even betterly.Medical injector 10 can construct in any known manner, with this In described plunger 12 be adapted.Medical injector 10 may include the reservoir 14 for accommodating injectable medicament, the reservoir 14, which can be drug canister or the reservoir 14, can be formed directly into medical injector 10.Reservoir 14 can have and it Associated one or more plugs, as known in the art.Medical injector 10 can also be equipped with and use In the needle 18 of injection, which can removably link or be attached on medical injector 10, such as form " column " cloth It sets.

Plunger 12 is elongated, and is general flat.Multiple ratchets 20 spaced apart are arranged along the length of plunger 12. In a kind of preferred arrangement, plunger 12 includes plate shape ontology 22, which has opposite the first front and second just Face 24,26.Ratchet 20 is arranged on the first front 24, and in another preferred arrangement, also is disposed on the second front 26. Preferably, the ratchet 20 on the first front and the second front 24,26 is axially aligned along the length of plunger 12.

Ratchet 20 is configured so that plunger 12 can carry out one-way movement.Specifically, with reference to Fig. 3, ratchet 20 is preferably It is zigzag, there is inclined surface 28 and shoulder stopper section 30.As shown in figure 3, on the first front and the second front 24,26 The inclined surface 28 of ratchet 20 be oriented, it is facing on identical general direction.It preferably presses substantially shoulder stopper section 30 Vertical orientation is extended transversely with from the first front and the second front 24,26.

Plunger 12 can also have one or more guide rails 27 extended from the first front 24 and/or the second front 26. Guide rail 27 can be formed as, across the notch of one or more correspondingly-shapeds formed in medical injector 10 to match And it slides.Guide rail 27 can provide stability during use, especially during the translation of plunger 12.

With reference to Fig. 4-6, plunger 12 is arranged in the ontology 32 of medical injector 10.Ontology 32 is including distal end 34 and closely Side end 36, the distal end 34 are arranged to be directed toward patient during injection, which is arranged to remote during injection From patient (Fig. 1).During use, medical injector 10 is configured so that plunger 12 can be wherein towards distal end 34 Distal direction on uniaxially move, but cannot be moved in the proximal direction of proximally facing end 36.In order to be conducive in this way One-way movement, be equipped at least one protractor 38, which is formed as to engagement pistons 12.Protractor 38 is configured to Enable plunger 12 towards 34 distal motion of distal end of ontology 32, but cannot towards ontology 32 proximal end 36 to Proximal movement.

Protractor 38 includes deflection pawl 40, and the deflection pawl 40 as schematically illustrated in figure 3, including tilts Engagement surface 42 and the stop surfaces 44 faced out.Protractor 38 can be bent outward, with when plunger 12 relative to it to remote Engagement surface 42 is allowed to rise along the inclined surface 28 of each ratchet 20 when moving in side.When distal motion the amount of full, Protractor 38 crosses ratchet 12, and under the intrinsic elasticity of protractor 38, to internal gearing, to which stop surfaces 44 stop with shoulder Stopper 30 is aligned.Preferably, stop surfaces 44 are formed as generally parallel with shoulder stopper section 30.When plunger 12 is backward (to close Side) movement when, shoulder stopper section 30 and stop surfaces 44 interferingly engage, thus prevent 12 proximal motion of plunger.At one In preferred embodiment, it is equipped with a pair of of protractor 38, is arranged on the first front and the second front 24,26 the two to abut against Ratchet 20 works, as Figure 4-Figure 6.It may further be preferable that equipped with a pair of of protractor 38, this is right in an axial direction to protractor 38 Standard, thus clamping effect for plunger 12 will be provided.This clamping effect can be that plunger 12 provides stable retentivity.

Protractor 38 can be formed as, by means of intrinsic elasticity, such as by means of the selection of material (for example, being moulded by thermoplasticity Material is formed), and there is flexibility.In addition, or selectively, protractor 38 may include suspending arm 46, which makes The pawl 40 that must be connected can be bent.Protractor 38 is formed as, and has natural, unbiased state as Figure 4-Figure 6, In, protractor 38 is positioned to work to the shoulder stopper section 30 against ratchet 20.Suspension arm 46 is formed with enough inside Memory, to provide the non-bias state for protractor 38.

Medical injector 10 also include actuator 48, the actuator 48 have bonding part 50, the bonding part 50 to Engage one or more ratchets 20.Bonding part 50 preferably includes engaging claw 52, which, which has, tilts table of joint Face 54 and the stop surfaces 56 faced out, it is similar with the construction of pawl 40 described above.Preferably, if there are two bonding parts 50, the two bonding parts 50 are arranged on the first front and the second front 24,26.

With reference to Fig. 4, plunger 12 is positioned to engage one in each plug 16.In order to cause the cause of medical injector 10 It is dynamic, as shown in figure 5, actuator 48 makes 50 proximal motion of bonding part to state motion is prepared.Protractor 38 prevents plunger 12 Proximal motion, thus allow actuator 48 relative to 12 proximal motion of plunger.At 12 remains stationary of plunger and joint portion In the case that points 50 relative to 12 proximal motion of plunger, one or more ratchets 20 are crossed in bonding part 50.Actuator 48 It is fully moved, to reach preparation state.

For the actuating of medical injector 10, actuator 48 is set to be moved from preparation state so that bonding part 50 is distad Movement.Bonding part 50 engages one or more ratchets 20, be especially for use in shoulder stopper section 30 and stop surfaces 56 it Between interference engagement.Specifically, bonding part 50 engages neighbouring distal side ratchet 20.The distal motion of bonding part 50 makes Plunger 12 is with its distal motion.The distal motion of plunger 12 causes plug 16 to be distally advanced again so that an injectant Amount is administered.Ratchet 20 can cross protractor 38 in a distal direction.

Wait for that by 10 applied dose size of medical injector be interval between ratchet 20 and/or when actuator 48 moves The function to nearside amount of movement to bonding part 50 when preparation state relative to ratchet 20.In order to generate fixed dosage, one Or more key 58 can be limited on medical injector 10 and/or actuator 48, one or more key 58 is formed as Be nested in corresponding channel 60, and along corresponding channel 60 slide, these corresponding channels 60 be formed in medical injector 10 and/or In actuator 48.As Figure 4-Figure 6, it is preferred that key 58 is formed on actuator 48, and channel 60 is formed in medical injection In device 10.With reference to Fig. 4, key 58 before the use, at the distal end in channel 60.When actuator 48 is moved to nearside, key 58 are proximally advanced nearest side position corresponding with the preparation state of actuator 48 in channel 60.Key 58 is in channel 60 The motion range of length limitation actuator 48 of stroke can be by 10 applied dose size of medical injector to limit.Such as Fig. 5 Shown in 6, key 58 is distally advanced into the farthest position with actuator 48 during use.

Actuator 48 shown in figs. 4-6 is rectilinearly-moved slide type actuator, and the rectilinearly-moved slide type actuator is direct by power It is applied on plunger 12.As the skilled person will recognize, actuator 48 can have various constructions.With reference to figure 7-8, actuator 48 may include the rocking bar 62 being pivotally mounted to thereon.Rocking bar 62 is frame shape, has first end 64 and second opposed end 66, the first end 64 be used for being pivotably mounted on actuator 48, which is used for It is pivotably mounted on medical injector 10.Bonding part 50 is arranged between first end and the second end 64,66.Such as Fig. 7 and 8 It is shown, can set there are two bonding part 50, with 20 collective effect of ratchet on the first front and the second front 24,26.

Note that the interval between first end and the second end 64,66 influences to pass from actuator 48 to the power of plunger 12 It passs, especially generates torque.Interval L and bonding part 50 between first end and the second end 64,66 is from first end Interval S1, the S2 in portion and the second end 64,66, influence how torque generates and be transmitted to plunger 12.

With reference to Fig. 9, shown in actuator 48 in the case where initially using preceding state, rocking bar 62 distad tilts.Referring to Fig.1 0, it causes Dynamic device 48 has progressed to preparation state, and by means of the rotation around the second end 66, warp-wise nearside pulls rocking bar 62, thus It is tilted in proximal direction.During this movement, bonding part 50 press with same way described above, cross one or more A ratchet 20.As shown in figure 11, actuator 48 is from state movement is prepared, to cause the actuating of medical injector 10.By means of causing Dynamic device 48 leaves the movement of preparation state, so that rocking bar 62 is distally advanced around the second end 66 so that bonding part 50 also causes Plunger 12 is distally advanced.Dosage size can be arranged by 58/ channel 60 of key described above, and/or the movement model of rocking bar 62 Enclose the two limitation.

As the skilled person will recognize, rocking bar 62 can be directly coupled on actuator 48, such as Fig. 9- Shown in 11.As the skilled person will recognize, multi link arrangement can be used for rocking bar 62 being connected to actuator On 48.Referring to Fig.1 2 and 13, one or more connecting rods 68 can be connected between rocking bar 62 and actuator 48, be used for providing Its power moved.Connecting rod 68 can utilize any arrangement that power can be transmitted to rocking bar 62 from actuator 48.Such as Figure 12 Shown in 13, using two connecting rods 68 (68A, 68B), connecting rod 68A is made to be pivotably connected on actuator 48 and pivotly It is connected on connecting rod 68B, and so that connecting rod 68B is pivotably connected on connecting rod 68A and be pivotably connected on rocking bar 62. Connecting rod 68A, 68B synergistically transfer force to rocking bar 62.

5-17 referring to Fig.1, actuator 48 can be arranged to are nonlinearly move.As seen in figs. 15-17, actuator 48 It can be formed to pivot around fulcrum 70.In the case where actuator 48 is pivoted out from medical injector 10 around fulcrum 70, Bonding part 50 is set to be moved to nearside.On the contrary, inside pivot of the actuator 48 around fulcrum 70 so that bonding part 50 is distad moved It is dynamic.It presses and same way described above and 12 collective effect of plunger bonding part 50.

Referring to Fig.1 5 and 16, shown in medical injector 10 under using preceding state.In order to facilitate the manipulation of actuator 48, Grasping ring can be provided or gasket 72, the grasping ring or gasket 72 extend radially outwardly from medical injector 10, to be conducive to cause The movement of dynamic device 48.In order to prepare to use, as as shown in arrow in figure 16, actuator 48 is made to be pivoted to preparation shape State, as shown in figure 17.In order to cause the actuating of medical injector 10, actuator 48 is made inwardly to be pivoted from preparation state, such as by As shown in arrow in Figure 17.

The size of dosage can be fixed with pivotable actuator 48 by the slewing area of limiting actuator 48.It is medical A part 74 for injector 10 can be configured to (especially be turned out) range to the rotation of limiting actuator 48, such It is corresponding with state is prepared to limit range.

Actuator 48 can be formed as linear slide actuator, but be constructed to be permeable to receive nonlinear force, by actuator 48 are adjusted to preparation state.8-27 referring to Fig.1, actuator 48 may include first part 48A, first part 48A according to Upper description is formed.In addition, actuator 48 may include rotatable second part 48B, the rotatable second part 48B connections Onto first part 48A, so as to be rotated relative to it.It is this to arrange that allowing actuator 48 to be rotated is adjusted to prepare shape State.Rotation adjustment is typically the feature of pen type injector, and may be preferred for some users.

Second part 48B can be accessible from the outside of medical injector 10, so as to be engaged from outside by user; Specifically, second part 48B extends from the proximal end 36 of ontology 32 to nearside.First part and second part 48A, 48B It is rotatably coupled in any known manner.As non-limiting examples, second part 48B could be formed with continuous loop 80, should Continuous loop 80 rests upon in the channel of first part 48A 82.The size and shape of ring 80 are configured to can be in channel 82 certainly It is rotated by ground, so that first part and second part 48A, 48B is axially fixed to move together.As those skilled in the art will As recognizing, ring 80 and channel 82 can be with reverse arrangements in first part and second part 48A, 48B.

As shown in figure 19, groove 84 is formed around the external of second part 48B.One or more keys 86 are arranged in medical injection On the peripheral part for entering device 10, such as it is arranged on the ontology 32 of second part 48B, the position of one or more key 86 It sets and is set to be sitting in groove 84 with size, so as to move along its length.The length of groove 84 defines second part The degree of rotation of 48B.According to one embodiment, at least part of groove 84 is spiral, to have helix shape. As will be recognized by those skilled in the art, one or more keys 86 can be arranged in the outer of second part 48B In portion, and corresponding groove 84 can be formed on peripheral part of medical injector 10.

Rotations of the second part 48B in the first rotation direction causes first part and second part 48A, 48B to nearside It is mobile so that bonding part 50 is accordingly moved proximally to preparation state.Specifically, the rotation of second part 48B causes It is moved to nearside, and first part 48A and bonding part 50 is consistently caused to be moved to nearside.Non- turn of first part 48A Dynamicly moved to nearside.The degree of rotation of the length limitation second part 48B of groove 84, thus limitation can be with applied dose. Once turn to setting dosage, by press second part 48B can administration dosage, this leads to second part 48B distad Advance, and correspondingly results in first part 48 and be non-rotatingly distally advanced together with bonding part 50.

About being distally advanced for second part 48B, it is preferred that second part 48B linearly advances without rotating. For this reason, it is preferred that groove 84 is formed with the first spiral section 84a and the second axial component 84b, second axial component 84b extends from the first spiral section 84a, generally parallel with the longitudinal axis of second part 48B.With reference to Figure 21, about this Kind arrangement, one or more keys 86 pass through the first spiral section in a proximal direction by means of the rotation of second part 48B 84a.Elbow curved 88 is limited to the joint of the first spiral section 84a and the second axial component 84b, the curved 88 limitation rotation journey of the elbow Degree, and thus limitation second part 48B moved to nearside.Elbow curved 88 limits the ready position of actuator 48.In order to activate, the Two part 48B are pressed, and are caused linearly distad when one or more keys 86 pass through the second axial component 84b Advance without rotating.This cause further through the engagement with bonding part 50 first part 48A be distally advanced and plunger 12 are distally advanced.The linear movement of second part 48B is allowed to be applied to power thereon and is fully uploaded in an axial direction It passs, and without resolving into two or more components.In this way, being applied on second part 48B whole actuating powers is all transmitted to cause Dynamic device 48.

For the single dosage pattern of this arrangement, can utilize the first spiral section and the second axial component 84a, Single group of 84b compositions.For multiple dosage, as shown in figure 22, groove 84 can extend into, and auxiliary screw shape part 84a ' can Directly to extend from the end of the second axial component 84b, extend in auxiliary axial component 84b ', and according to actual needs according to This is analogically arranged.According to one embodiment, series that the first spiral section 84a and the second axial component 84b are formed can be with It is continuously limited around second part 48B, to advantageously form multiple dosage.According to one embodiment, about one or more The correspondence group of key 86 can utilize more than one groove 84.Moreover, one or more grooves in each groove 84 and each key 86 In one or more keys can be arranged on the second part 48B and/or peripheral part of medical injector 10.

Preferably, it should the edges second part 48B be avoided to rotate backward.For this purpose, as shown in figs. 23-24, it is one or more Pawl 90 can be formed on second part 48B, be formed as to one or more placed channels 92 of engagement in snap engagement, described One or more placed channels 92 are formed in around second part 48B on medical injector 10, are such as formed on ontology 32.It is preferred that Ground, placed channel 92 are arranged to corresponding in ready position with second part 48B, and the positioning of such a ready position is logical Road 92 is elongated, to which pawl 90 can be moved with second part 48B during dosage is applied along its length.Such as this field skill As art personnel will be recognized that, pawl 90 (one or more) can be formed on medical injector 10, and be positioned logical Road can be formed on second part 48B.

It is undesirably especially after injection in addition, along the reversed axial movement of the second axial component 84b.For This, as shown in figs. 25 and 26, locking tab 94 be arranged on second part 48B, the locking tab 94 be configured to note The position for terminating to coincide is penetrated (for example, reaching the second axial component in one or more keys 86 in the end of dose stroke The position that the end of 84b coincides) in engagement in snap engagement to locking channel 96.The axial movement of second part 48B thus by Limitation.Locking channel 96 can be configured to, by means of the rotation of second part 48B allow locking tab 94 rotation so as to locking Channel 96 detaches, to be prepared with post dose.Locking channel 96 is formed on peripheral part of medical injector 10, is such as formed in On ontology 32.As the skilled person will recognize, locking tab 94 can be formed on medical injector 10, and And locking channel 96 can be arranged on second part 48B.

In addition, as the skilled person will recognize, by means of arrangement mentioned above, especially by means of The use of the first part and second part 84a, 84b of groove 84, dosage are fixed dosages.According to one of permission variable dose Embodiment is distally advanced period in second part 48B, second part 48B can be allowed to rotate, while one or more Key 86 is advanced along groove 84.Thus, in this embodiment, as shown in figure 27, it is only necessary to which the spiral section of groove 84 is provided 84a.About this arrangement, second part 48B can turn to any position along groove 84 (84a), by by means of agent in terms of allowing The rotating backward and setting dosage along groove 84 (84a) of amount.Known scale or other marks can in the art It is corresponding with the rotation displacement of second part 48B to be arranged to, to provide the instruction of setting dosage value (dose amount).For Limitation rotating backward undesirably, and in order to be maintained at the position at setting dosage can utilize and releasable keep filling It sets, as known in the art.

First part and second part 48A, 48B are utilized together with any one feature in each feature described herein. Preferably, first part and second part 48A, 48B and rocking bar 62 are used together.

Figure 28 is the stereogram according to the medical injector 10 of another embodiment of the present invention.With reference to Figure 28-33, medical injection It includes ontology 32, knob 100, actuator 48 and cap 101 to enter device 10, which is pivotally connected on ontology 32, The actuator 48 is arranged in ontology 32, which is connected on actuator 48.As shown in figure 29, actuator 48 includes recessed Slot 84, as described above.Actuator 48 also includes axial notch 102.Axial notch 102 and 104 phase interaction of axial bond With (being shown in FIG. 30), which is arranged on the inside of ontology 32, to guide actuator 48 relative to ontology 32 It is axially moved, and prevents actuator 48 relative to the rotation of ontology 32.As the skilled person will recognize, axis It can be arranged in groove 102 on the inside of ontology 32, and axial bond 104 can be arranged on actuator 48, without departing from The scope of the present invention.

As shown in figure 31, ontology 32 also includes the circumferential groove 106 being arranged at its proximal end, is used for and knob 100 It is connected, as described in more detail hereinbelow.In addition, as described in more detail hereinbelow, ontology 32 includes suspension , circumference arm 120, which has denation 122, which is arranged in the end of arm 120, and It projects radially outwardly.

Figure 32 is the stereogram of the distal end of knob 100, and Figure 33 is the stereogram of the proximal end of knob 100.Such as figure Shown in 32, knob 100 includes the connector 108 circumferentially and projected radially inward.According to one embodiment, connection Device 108 is approximate wedge shape.For assembling medical injector 10, knob 100 is distad inserted in the proximal end of ontology 32, directly In the circumferential groove 106 for sliding into ontology 32 to connector 108, knob 100 is connected on ontology 32 by this.Connector 108 Knob 100 is fixed on ontology 32 by wedge-type shape, is prevented knob 100 from being moved to nearside relative to ontology 32 substantially, is held simultaneously Perhaps knob 100 is rotated relative to ontology 32.

As shown in figure 32, connector 108 is arranged in the major diameter part 110 of knob 100.It also is disposed on knob 100 In major diameter part 110 is triangular groove 112.Triangular groove 112 and the denation 122 on arm 120 are mutual Effect, to allow knob 100 to be rotated in a unidirectional manner relative to ontology 32.That is triangular groove 112 and denation 122 Interaction, to allow knob 100 to be rotated only along the direction for making plunger 12 be proximally advanced.Knob 100, which also has, to be reduced Diameter portion 114 prevents knob after the reduction diameter portion 114 is connected between connector 108 and circumferential groove 106 It is moved to nearside relative to ontology.In addition, cam shape protrusion or key 116 are projected radially inward from diameter portion 114 is reduced.Class It is similar to key 86 described above, key 116 and the groove 84 of actuator 48 interact, the rotational motion of knob 100 converted It is axially moved to nearside at actuator 48.After actuator 48 is axially moved to nearside, user presses cap 101 (even It is connected on actuator 48), to be distally moved actuator 48 relative to ontology 32, and thus plunger 12 is made to be distally advanced.

With reference to Figure 33, knob 100 is at its proximal end also including radially rib 118 outstanding.Rib 118, which plays, to be made The effect at user interface, to allow user to hold and rotate knob 100.

As the skilled person will recognize, the medical injector 10 with various features can be utilized.Ginseng According to Figure 12-14, dose counter can be set about medical injector 10, which, which provides, to be administered can be obtained agent The instruction of the quantity of amount.It, specifically can be from for example, a series of dosage indicator holes 76 can be formed in medical injector 10 Its outside is seen.In the example that one provides, pointer 78 can be arranged on actuator 48, and be formed to pass through Single hole in each dosage indicator hole 76 and be seen.During use, with 12 1 dosage of plunger then dosage (dose by dose) is distally advanced, and pointer 78 equally advances along at the dosage indicator hole 76 of series.According to one embodiment, The instruction of the quantity of doses remaining is provided positioned at the quantity of the dosage indicator hole 76 in the distal side of pointer 78.It is indicated with dosage is appeared in Pointer 78 in the farthest side in hole 76 provides the instruction of " doses remaining for not being suitable for application ".

Preferably, pointer 78 by relative to medical injector 10 be located at dosage indicator hole 76 near part comparison Color is formed, to pass through 76 easily visible pointer 78 of dosage indicator hole.

In addition, according to one embodiment shown in Figure 34, prominent limitation rib 98 can be from the distal part of plunger 12 Extend, protrusion limitation rib 98 is arranged to coincide with the dosage setting on plunger 12, which is arranged and in reservoir 14 Last available medication amount it is corresponding.Correspondingly, about the predetermined extent of plunger 12 being distally advanced, the limitation formation of rib 98 For interferingly to engage a part for actuator 48, and prevent to pass through its proximal motion.In such a way, actuator 48 The dosage of setting cannot be more than the available quantity in reservoir 14.

While there has been shown and described that only several embodiments of the invention, but the present invention is not limited to the implementations of description Example.On the contrary, it would be recognized by those skilled in the art that can carry out not departing from the principle and spirit of the invention for these embodiments Various change, the scope of the present invention limits by claims and its equivalent.

Claims (9)

1. a kind of medical injector, including:
Ontology, the ontology have distal end and proximal end;
Plunger, the plunger are movably disposed in the ontology, and the plunger has the multiple intervals arranged along its length The ratchet opened, the selectively moved plug of plunger, to distribute medicament from the medical injector;
Protractor, the protractor is arranged in the ontology, to engage the plunger, to allow the plunger distad to move It moves and prevents the plunger from being moved to nearside substantially;
Actuator, the actuator have bonding part, and the actuating is allowed in the bonding part to engage the plunger Device is mobile to nearside relative to the plunger and the actuator is prevented to be distally moved relative to the plunger substantially;With And
Rotatable parts, the rotatable parts are used for making the bonding part move to nearside relative to the plunger and the ontology It is dynamic;
Wherein, when actuator is moved proximally to preparation state relative to the ontology, one or more ratchets cross institute Bonding part is stated, so that the actuator is moved relative to the plunger to nearside;And
Wherein, when the actuator is distally moved relative to the ontology from the preparation state, the actuator engagement One or more ratchets make the plunger be distally moved relative to the protractor, so that the plug is distally moved And distribute medicament from the medical injector;
Wherein, the actuator includes:
First activator portion, the bonding part are arranged on first activator portion;And
The rotatable parts, the rotatable parts include the second activator portion, second activator portion and described first Activator portion is rotatably coupled;
Wherein, second activator portion can rotationally be moved to the preparation state, thus make first actuating Device part is moved relative to the ontology to nearside, and is rotationally moved to the preparation in second activator portion When state, one or more ratchets cross the bonding part, so that first activator portion and the second actuator portion Split-phase moves the plunger to nearside;And
Wherein, second activator portion can be distally moved relative to the ontology from the preparation state, thus to Distal side and non-rotatingly move first actuator, and second activator portion from the preparation state distad When mobile, the bonding part engages one or more ratchets, and the plunger is made to be distally moved, so that the plug It is distally moved and distributes medicament from the medical injector.
2. medical injector according to claim 1, wherein:
One of second activator portion and the ontology have groove, and second activator portion and described There are the other of ontology corresponding keys, the corresponding keys to be slidably received in the groove;And
The key causes the movement of second activator portion relative to the movement of the groove.
3. medical injector according to claim 2, wherein the groove includes substantially spiral section, and described Key leads to the rotation of second activator portion relative to the movement of the spiral section.
4. medical injector according to claim 3 further includes the mark that user can be seen that, it is used for when the key is in institute State dosage needed for being set when being moved in spiral section.
5. medical injector according to claim 3, wherein the groove further includes axial component, and the key phase Second activator portion is caused to be axially moveable the movement of the axial component, for making the actuator from described Preparation state is distally moved.
6. medical injector according to claim 5, wherein the groove includes multiple spiral sections, the multiple Spiral section is successively connected by corresponding multiple axial components.
7. medical injector according to claim 1, wherein one of second activator portion and the ontology With placed channel, and the other of second activator portion and the ontology have corresponding pawl, the spine Placed channel described in pawl engagement in snap engagement to allow second activator portion to be rotated in a first direction, and prevents described Two actuators edge rotates backward.
8. medical injector according to claim 5, wherein:
One of second activator portion and the ontology have placed channel, and second activator portion and The other of described ontology has corresponding pawl, placed channel described in the pawl engagement in snap engagement, to allow described second Activator portion is rotated in a first direction and engages the pawl, and prevents the second actuator edge from rotating backward;And
The placed channel is axial slender, to allow second activator portion to be axially moveable.
9. medical injector according to claim 5, wherein one of second activator portion and the ontology With locking channel, and the other of second activator portion and the ontology have corresponding locking tab, this is right Answer locking tab at position corresponding with the end of the administered from the medical injector, with the locking channel Engagement in snap engagement, to prevent second activator portion non-rotatingly proximal motion.
CN201610042183.2A 2011-03-17 2011-03-17 Medical injector with ratchet-type plunger CN105498049B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201180070446.6A CN103501835B (en) 2011-03-17 2011-03-17 There is the medical injector of ratchet-type plunger
CN201610042183.2A CN105498049B (en) 2011-03-17 2011-03-17 Medical injector with ratchet-type plunger

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610042183.2A CN105498049B (en) 2011-03-17 2011-03-17 Medical injector with ratchet-type plunger

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Application Number Title Priority Date Filing Date
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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1482928A (en) * 2000-12-22 2004-03-17 Dca设计国际有限公司 Drive mechanism for an injection device
CN1607015A (en) * 1997-11-18 2005-04-20 D·马赫卡 萨克哈拉姆 Single-use safety syringe
WO2005070483A1 (en) * 2004-01-26 2005-08-04 The Medical House Plc Needle-free injection device
CN101035579A (en) * 2004-10-04 2007-09-12 塞诺菲—安万特德国有限公司 Dose display mechanism for a drug delivery device
WO2010033770A2 (en) * 2008-09-18 2010-03-25 Becton, Dickinson And Company Medical injector with ratcheting plunger
WO2010033778A2 (en) * 2008-09-18 2010-03-25 Becton, Dickinson And Company Medical injector with dose knob activation for automated reconstitution
CN101854968A (en) * 2007-09-25 2010-10-06 克劳斯·施密特·默勒 Dose delivery device with gearing mechanism

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1607015A (en) * 1997-11-18 2005-04-20 D·马赫卡 萨克哈拉姆 Single-use safety syringe
CN1482928A (en) * 2000-12-22 2004-03-17 Dca设计国际有限公司 Drive mechanism for an injection device
WO2005070483A1 (en) * 2004-01-26 2005-08-04 The Medical House Plc Needle-free injection device
CN101035579A (en) * 2004-10-04 2007-09-12 塞诺菲—安万特德国有限公司 Dose display mechanism for a drug delivery device
CN101854968A (en) * 2007-09-25 2010-10-06 克劳斯·施密特·默勒 Dose delivery device with gearing mechanism
WO2010033770A2 (en) * 2008-09-18 2010-03-25 Becton, Dickinson And Company Medical injector with ratcheting plunger
WO2010033778A2 (en) * 2008-09-18 2010-03-25 Becton, Dickinson And Company Medical injector with dose knob activation for automated reconstitution

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