CN105435358A - Implantable intracranial drug delivery cannula suitable for neurosciences research - Google Patents
Implantable intracranial drug delivery cannula suitable for neurosciences research Download PDFInfo
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- CN105435358A CN105435358A CN201510835586.8A CN201510835586A CN105435358A CN 105435358 A CN105435358 A CN 105435358A CN 201510835586 A CN201510835586 A CN 201510835586A CN 105435358 A CN105435358 A CN 105435358A
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- drug delivery
- delivery tube
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- intubate
- cannula
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Abstract
The invention discloses an implantable intracranial drug delivery cannula suitable for neurosciences research. The drug delivery cannula comprises a microprocessor, a reflective mirror, a fixing support, an inner cavity, a first drug delivery pipe, a seal sleeve, a second drug delivery pipe and an intracranial body; a drug delivery cannula outlet and a drug delivery hole formed in the drug delivery cannula outlet are formed in one end of the first drug delivery pipe, the inner cavity is formed in the first drug delivery pipe, light guiding fibers are arranged between the inner cavity and the inner side of the first drug delivery pipe, and the reflective mirror is arranged at one ends of the light guiding fibers; the microprocessor is arranged at the other end of the first drug delivery pipe, one side of the first drug delivery pipe is provided with the second drug delivery pipe and a drug delivery cannula inlet formed in one end of the second drug delivery pipe, and the drug delivery cannula inlet is sleeved with the seal sleeve. According to the implantable intracranial drug delivery cannula suitable for neurosciences research, a cannula material mets the requirement of medical implantation, fixity and leakproofness are good, and a cannula inner core is high in operability and intellectuality.
Description
Technical field
The present invention relates to technical field of medical equipment, specifically a kind of implanted intracranial administration intubate being applicable to Neuroscience Research.
Background technology
At present, the encephalic cannula that China is being applied to brain science research is technically still immature, each university or research institution all carry out scientific research with homemade encephalic cannula, but self-control intubate has a lot of shortcoming, such as: (1) cannula material does not reach medical implant requirement: with general industry steel pipe as implantation tubing, cannot reach medical, the physical and chemical stability requirement of biology implant, it discharges poisonous metal or nonmetallic ion in brain, cause neurocyte operation irregularity or pathological changes necrosis, (2) stationarity is poor: homemade encephalic cannula does not have fixed pedestal structure, from amechanical angle, comparatively fragility fixing between intubate and skull, when the chronic experiment that the cycle of carrying out is longer, because the distortion of fixing glue or dental cement is aging, intubate is made to be easy to displacement or directly to come off from skull surface, (3) seal is poor: self-control intubate does not have sealing cap structure substantially, very well intracranial and cranium external environment strictly can not be kept apart effectively, it is the critical defect that self-control intubate is difficult to overcome that microorganism enters intracranial initiation intracranial infection, (4) intubate inner core operability is poor: be the thin metal tube of the ratio cannula inner diameter found of experimenter oneself owing to making the filling inner core of intubate by oneself, not only also there is the problem of physical and chemical stability, toxic reaction or degraded is caused to be got rusty, and be more difficult to fully up to expectations be, its diameter is difficult to reach desirable, after causing intubate to be implanted, cerebrospinal fluid in brain can be present between inner core and intubate tube wall because of capillarity in a large number, and in cerebrospinal fluid rich in protein and inorganic salt once separate out, the then as easy as rolling off a log effect playing adhesive, intubate and inner core are glued together, inner core is caused to be difficult to take out, this phenomenon is comparatively general in self-control intubate, (5) intelligent difference, in administration process, medical worker cannot understand the situation of patient's intracranial, once go wrong, can not take emergency measures in time, for this reason, we propose a kind of implanted intracranial administration intubate being applicable to Neuroscience Research.
Summary of the invention
The object of the present invention is to provide a kind of implanted intracranial administration intubate being applicable to Neuroscience Research, this is applicable to the implanted intracranial administration intubate of Neuroscience Research, cannula material reaches medical embedded requirement, stationarity is good, good leak tightness, intubate inner core operability are high, by force intelligent, to solve the problem proposed in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
A kind of implanted intracranial administration intubate being applicable to Neuroscience Research, comprise microprocessor, illuminator, fixed support, inner chamber, first delivery tube, sealing shroud, second delivery tube and intracranial body, the dosing holes that described first delivery tube one end is provided with medicine-feeding canula outlet and is arranged in medicine-feeding canula outlet, described first delivery tube inside is provided with inner chamber, optical fibers is provided with between inside described inner chamber and described first delivery tube, described optical fibers one end is provided with illuminator, the described first delivery tube other end is provided with microprocessor, described first delivery tube side is provided with the second delivery tube and is arranged on the medicine-feeding canula import of second delivery tube one end, described medicine-feeding canula import is provided with sealing shroud, described first delivery tube two bottom sides is provided with fixed support, described medicine-feeding canula import is placed in intracranial body.
As the further scheme of the present invention: described microprocessor internal is provided with picture processor and is arranged on the intracranial illness analysis in picture processor.
As the further scheme of the present invention: described intracranial illness analysis, by the information structure output by analysis after process, exports finally by display screen.
As the further scheme of the present invention: described illuminator becomes 30 degree of angles with optical fibers, described first delivery tube and described fixed support are medical fibre material.
Compared with prior art, the invention has the beneficial effects as follows: because the first delivery tube is medical fibre material, reach medical, the physical and chemical stability requirement of biology implant, accelerate the treatment of neurocyte, because fixed support is arranged on the first delivery tube both sides, the effect of fixing intubate can be played, avoid dislodged cannula or directly come off from skull surface, due to medicine-feeding canula import being provided with sealing shroud, intracranial and cranium external environment is can be good at strictly effectively to keep apart, microorganism is avoided to enter intracranial, cause patient's intracranial infection, because illuminator becomes 30 degree of angles with optical fibers, microprocessor can be reflexed to by maximized for light source, analytical effect is better.
Accompanying drawing explanation
Fig. 1 is the overall structure schematic diagram of implanted intracranial administration intubate of the present invention;
Fig. 2 is that implanted intracranial administration intubate of the present invention inserts drug delivery structure schematic diagram;
Fig. 3 is implanted intracranial administration intubate control system schematic diagram of the present invention;
In figure: the outlet of 1-microprocessor, 2-illuminator, 3-optical fibers, 4-fixed support, 5-medicine-feeding canula, 6-inner chamber, 7-first delivery tube, the import of 8-medicine-feeding canula, 9-sealing shroud, 10-second delivery tube, 11-intracranial body, 12-dosing holes.
Detailed description of the invention
Be described in more detail below in conjunction with the technical scheme of detailed description of the invention to this patent.
Refer to Fig. 1-3, a kind of implanted intracranial administration intubate being applicable to Neuroscience Research, comprise microprocessor 1, illuminator 2, fixed support 4, inner chamber 6, first delivery tube 7, sealing shroud 9, second delivery tube 10 and intracranial body 11, the dosing holes 12 that described first delivery tube 7 one end is provided with medicine-feeding canula outlet 5 and is arranged in medicine-feeding canula outlet 5, described first delivery tube 7 inside is provided with inner chamber 6, optical fibers 3 is provided with between inside described inner chamber 6 and described first delivery tube 7, described optical fibers 3 one end is provided with illuminator 2, described first delivery tube 7 other end is provided with microprocessor 1, described first delivery tube 7 side is provided with the second delivery tube 10 and is arranged on the medicine-feeding canula import 8 of second delivery tube 10 one end, described medicine-feeding canula import 8 is provided with sealing shroud 9, described first delivery tube 7 two bottom sides is provided with fixed support 4, described medicine-feeding canula import 8 is placed in intracranial body 11.
Described microprocessor 1 inside is provided with picture processor and is arranged on the intracranial illness analysis in picture processor, described intracranial illness analysis is by the information structure output by analysis after process, export finally by display screen, described illuminator 2 and optical fibers 3 one-tenth 30 degree of angles, described first delivery tube 7 is medical fibre material with described fixed support 4, because the first delivery tube 7 is medical fibre material, reach medical, the physical and chemical stability requirement of biology implant, accelerate the treatment of neurocyte, because fixed support 4 is arranged on the first delivery tube 7 both sides, the effect of fixing intubate can be played, avoid dislodged cannula or directly come off from skull surface, due to medicine-feeding canula import 8 being provided with sealing shroud 9, intracranial and cranium external environment is can be good at strictly effectively to keep apart, microorganism is avoided to enter intracranial, cause patient's intracranial infection, due to illuminator 2 and optical fibers 3 one-tenth 30 degree of angles, microprocessor 1 can be reflexed to by maximized for light source, analytical effect is better, this is applicable to the implanted intracranial administration intubate of Neuroscience Research, cannula material reaches medical embedded requirement, stationarity is good, good leak tightness, intubate inner core operability is high, by force intelligent, greatly improve therapeutic effect.
It should be noted that, the present invention is a kind of circulating water treatment recycling equipment, during work, first first delivery tube 7 is implanted to patient's intracranial by medical worker, fixed support 4 plays the effect of support first delivery tube 7, then sealing shroud 9 is opened, then injectable drug, after drug injection completes, covers sealing shroud 9 immediately, microorganism is avoided to enter intracranial, cause patient's intracranial infection, meanwhile, intracranial image is reflexed to microprocessor 1 through illuminator 2 by optical fibers 3, picture is analyzed by microprocessor 1, and medical worker observes patient's intracranial situation.
Last it is noted that the foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (4)
1. one kind is applicable to the implanted intracranial administration intubate of Neuroscience Research, comprise microprocessor (1), illuminator (2), fixed support (4), inner chamber (6), first delivery tube (7), sealing shroud (9), second delivery tube (10) and intracranial body (11), it is characterized in that, the dosing holes (12) that described first delivery tube (7) one end is provided with medicine-feeding canula outlet (5) and is arranged on medicine-feeding canula outlet (5), described first delivery tube (7) inside is provided with inner chamber (6), optical fibers (3) is provided with between described inner chamber (6) and described first delivery tube (7) inner side, described optical fibers (3) one end is provided with illuminator (2), described first delivery tube (7) other end is provided with microprocessor (1), described first delivery tube (7) side is provided with the second delivery tube (10) and is arranged on the medicine-feeding canula import (8) of the second delivery tube (10) one end, described medicine-feeding canula import (8) is provided with sealing shroud (9), described first delivery tube (7) two bottom sides is provided with fixed support (4), described medicine-feeding canula import (8) is placed in intracranial body (11).
2. a kind of implanted intracranial administration intubate being applicable to Neuroscience Research according to claim 1, it is characterized in that, described microprocessor (1) inside is provided with picture processor and is arranged on the intracranial illness analysis in picture processor.
3. a kind of implanted intracranial administration intubate being applicable to Neuroscience Research according to claim 2, is characterized in that, described intracranial illness analysis, by the information structure output by analysis after process, exports finally by display screen.
4. a kind of implanted intracranial administration intubate being applicable to Neuroscience Research according to claim 1, it is characterized in that, described illuminator (2) becomes 30 degree of angles with optical fibers (3), and described first delivery tube (7) and described fixed support (4) are medical fibre material.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510835586.8A CN105435358B (en) | 2015-11-25 | 2015-11-25 | A kind of implanted intracranial administration intubation suitable for Neuroscience Research |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510835586.8A CN105435358B (en) | 2015-11-25 | 2015-11-25 | A kind of implanted intracranial administration intubation suitable for Neuroscience Research |
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| CN105435358A true CN105435358A (en) | 2016-03-30 |
| CN105435358B CN105435358B (en) | 2018-12-21 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021097963A1 (en) * | 2019-11-18 | 2021-05-27 | 中国科学院深圳先进技术研究院 | Disposable impermeable intracranial drug administration device |
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| CN201179262Y (en) * | 2008-04-28 | 2009-01-14 | 徐玉灿 | Novel epidural space puncture anaesthesia package |
| CN201271426Y (en) * | 2008-09-26 | 2009-07-15 | 张峰 | Y-shaped intracalvarium drainage tube |
| US20120004629A1 (en) * | 1999-06-04 | 2012-01-05 | Medtronic Ps Medical, Inc. | Subdural evacuation port aspiration device |
| CN202740589U (en) * | 2012-08-28 | 2013-02-20 | 张金刚 | Puncture drainage tube for intracranial hematoma |
| CN103800977A (en) * | 2014-01-27 | 2014-05-21 | 广西壮族自治区人民医院 | Optical fiber for administration |
| CN204655763U (en) * | 2015-03-03 | 2015-09-23 | 惠州市第三人民医院 | A kind of painless stomach tube |
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2015
- 2015-11-25 CN CN201510835586.8A patent/CN105435358B/en active Active
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|---|---|---|---|---|
| CN85205102U (en) * | 1985-11-26 | 1986-12-17 | 薛络 | Z-formed, hard colonoscope composed of annularly distributed optical fibre and cold light source |
| US6152933A (en) * | 1997-11-12 | 2000-11-28 | Stereotaxis, Inc. | Intracranial bolt and method of placing and using an intracranial bolt to position a medical device |
| US20120004629A1 (en) * | 1999-06-04 | 2012-01-05 | Medtronic Ps Medical, Inc. | Subdural evacuation port aspiration device |
| CN1891310A (en) * | 2005-07-04 | 2007-01-10 | 中国科学院心理研究所 | Implanted intracranial administration intubate suitable for neuroscience research |
| CN201179262Y (en) * | 2008-04-28 | 2009-01-14 | 徐玉灿 | Novel epidural space puncture anaesthesia package |
| CN201271426Y (en) * | 2008-09-26 | 2009-07-15 | 张峰 | Y-shaped intracalvarium drainage tube |
| CN202740589U (en) * | 2012-08-28 | 2013-02-20 | 张金刚 | Puncture drainage tube for intracranial hematoma |
| CN103800977A (en) * | 2014-01-27 | 2014-05-21 | 广西壮族自治区人民医院 | Optical fiber for administration |
| CN204655763U (en) * | 2015-03-03 | 2015-09-23 | 惠州市第三人民医院 | A kind of painless stomach tube |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021097963A1 (en) * | 2019-11-18 | 2021-05-27 | 中国科学院深圳先进技术研究院 | Disposable impermeable intracranial drug administration device |
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| CN105435358B (en) | 2018-12-21 |
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