CN105429534A - High-accuracy liquid injection control system and method - Google Patents

High-accuracy liquid injection control system and method Download PDF

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Publication number
CN105429534A
CN105429534A CN201510931891.7A CN201510931891A CN105429534A CN 105429534 A CN105429534 A CN 105429534A CN 201510931891 A CN201510931891 A CN 201510931891A CN 105429534 A CN105429534 A CN 105429534A
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CN
China
Prior art keywords
fluid injection
stepping motor
reservoir quantity
driving stepping
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510931891.7A
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Chinese (zh)
Inventor
沙利烽
胥法伟
吴冬
郭金龙
苗新利
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suzhou Hybiome Biomedical Engineering Co Ltd
Original Assignee
Suzhou Hybiome Biomedical Engineering Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suzhou Hybiome Biomedical Engineering Co Ltd filed Critical Suzhou Hybiome Biomedical Engineering Co Ltd
Priority to CN201510931891.7A priority Critical patent/CN105429534A/en
Publication of CN105429534A publication Critical patent/CN105429534A/en
Pending legal-status Critical Current

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Classifications

    • HELECTRICITY
    • H02GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02PCONTROL OR REGULATION OF ELECTRIC MOTORS, ELECTRIC GENERATORS OR DYNAMO-ELECTRIC CONVERTERS; CONTROLLING TRANSFORMERS, REACTORS OR CHOKE COILS
    • H02P8/00Arrangements for controlling dynamo-electric motors of the kind having motors rotating step by step
    • H02P8/40Special adaptations for controlling two or more stepping motors

Abstract

The invention discloses a high-accuracy liquid injection control system and method. The system comprises an upper computer, a controller, a large-volume liquid injection mechanism and a small-volume liquid injection mechanism, wherein the large-volume liquid injection mechanism and the small-volume liquid injection mechanism are in correspondence to different liquid injection accuracies, the large-volume liquid injection mechanism comprises a large-volume pump, a first driving stepping motor and a first motor driver, the small-volume liquid injection mechanism comprises a small-volume pump, a second driving stepping motor and a second motor driver, the upper computer is connected with the controller and used for outputting a liquid injection instruction to the controller, and the controller is used for controlling the running of the first motor driver or the second motor driver according to the liquid injection instruction so as to drive the first driving stepping motor or the second driving stepping motor to run and then drive the large-volume pump or the small-volume pump to perform liquid injection. By the high-accuracy liquid injection control system, the corresponding liquid injection mechanism can be selected according to required liquid injection volume, and thus, high-accuracy liquid injection corresponding to different accuracy requirements is achieved.

Description

A kind of high accuracy fluid injection control system and method
Technical field
The present invention relates to technical field of medical instruments, particularly a kind of high accuracy fluid injection control system being applicable to in-vitro diagnosis equipment.
Background technology
The diagnostic method that current medical domain the most generally uses---in-vitro diagnosis, refers to that the body fluid of collection human body, excreta, secretion carry out chemical composition or chemical reaction analysis, thus judges human lesion.As chemiluminometry, molecular diagnosis.These diagnostic methods, all adopt automatically or semi-automated instrument carries out application of sample, analyze, and provide diagnosis report.
General in-vitro diagnosis equipment needs to carry out adding sample, reagent adding, and sample size is general less, within 20ul, amount of reagent determined according to different mensuration projects, has also having of the large liquid measure of needs to need low consumption of the liquid.And the accuracy requirement of application of sample is higher equally, generally+-5%, precision General Requirements is less than 3%.
Summary of the invention
The technical problem to be solved in the present invention is: provide a kind of fluid injection control system, and it can select corresponding mechanism for filling liquid according to required reservoir quantity, thus realizes the high accuracy fluid injection of corresponding different accuracy requirement.
The technical scheme that the present invention takes is specially: a kind of high accuracy fluid injection control system, comprises large liquid measure mechanism for filling liquid and the low consumption of the liquid mechanism for filling liquid of host computer, controller and corresponding different fluid injection precision;
Above-mentioned large liquid measure mechanism for filling liquid comprises large liquid measure pump, the first Driving Stepping Motor and the first motor driver; The input connection control device of the first motor driver, output connects the first Driving Stepping Motor; The output shaft of the first Driving Stepping Motor connects large liquid measure pump;
Above-mentioned low consumption of the liquid mechanism for filling liquid comprises low consumption of the liquid pump, the second Driving Stepping Motor and the second motor driver; The input connection control device of the second motor driver, output connects the second Driving Stepping Motor; The output shaft of the second Driving Stepping Motor connects low consumption of the liquid pump;
Host computer connection control device, to export fluid injection instruction to controller, controller controls the operation of the first motor driver or the second motor driver according to fluid injection instruction, thus drive the first Driving Stepping Motor or the second Driving Stepping Motor to run, carry out fluid injection to drive large liquid measure pump or low consumption of the liquid pump.
In the present invention, host computer can adopt computer, and controller can adopt microcontroller chip, and stepper motor driver can adopt existing stepper motor driver, and large liquid measure pump and low consumption of the liquid pump also adopt existing by stepper motor driven topping-up pump.Staff is by upper computer selecting reservoir quantity, fluid injection instruction containing reservoir quantity data is sent to controller by host computer, namely controller starts large liquid measure pump or low consumption of the liquid pump according to reservoir quantity demand estimation, thus sends drive singal to corresponding motor driver.Driving for stepping motor is also prior art.
Concrete, the reservoir quantity scope of large liquid measure pump of the present invention is 20ul ~ 200ul, and the reservoir quantity scope of low consumption of the liquid pump is for being less than 20ul.This arranges the requirement for large reservoir quantity and little reservoir quantity of respectively corresponding in-vitro diagnosis apparatus field.
Further, the present invention also comprises alarm output unit, the input connection control device of alarm output unit.When reservoir quantity requires to be greater than 200ul, controller will by alarm output unit output alarm signal, so that staff verifies reservoir quantity requirement.
The present invention also discloses a kind of fluid injection control method based on said system, comprises the following steps:
Step one, send fluid injection instruction by host computer to controller, fluid injection instruction comprises reservoir quantity data;
Step 2, controller receives fluid injection instruction, and extracts the reservoir quantity data in fluid injection instruction, and judges: as reservoir quantity is less than 20ul, then select low consumption of the liquid mechanism for filling liquid to carry out fluid injection, go to step three; Be less than 200ul as reservoir quantity is greater than 20ul, then select large liquid measure mechanism for filling liquid to carry out fluid injection, go to step four; As reservoir quantity is greater than 200ul, then go to step five;
Step 3, according to reservoir quantity data, and unit step number reservoir quantity during the second Driving Stepping Motor driving low consumption of the liquid pump, calculate the step number to be driven of the second Driving Stepping Motor, then control the second Driving Stepping Motor by the second motor driver and run corresponding step number, the actual reservoir quantity of low consumption of the liquid pump is conformed to the reservoir quantity data in fluid injection instruction;
Step 4, according to reservoir quantity data, and the unit step number reservoir quantity of the first Driving Stepping Motor when driving large liquid measure pump, calculate the step number to be driven of the second Driving Stepping Motor, then control the first Driving Stepping Motor by the first motor driver and run corresponding step number, the actual reservoir quantity of large liquid measure pump is conformed to the reservoir quantity data in fluid injection instruction;
Step 5, output alarm signal.
Beneficial effect of the present invention is: carry out in in-vitro diagnosis process of the test utilizing chemical luminescence detector device, utilize system and method for the present invention, corresponding mechanism for filling liquid can be selected to carry out the interpolation of sample or reagent according to actual reservoir quantity demand, and meet corresponding required precision.Fluid injection efficiency is improved, and also improves efficiency and the result accuracy of in-vitro diagnosis test.
Accompanying drawing explanation
Figure 1 shows that present system structural representation;
Figure 2 shows that the inventive method schematic flow sheet.
Embodiment
Further describe below in conjunction with the drawings and specific embodiments.
As shown in Figure 1, high accuracy fluid injection control system of the present invention, comprises large liquid measure mechanism for filling liquid and the low consumption of the liquid mechanism for filling liquid of host computer, controller and corresponding different fluid injection precision;
Above-mentioned large liquid measure mechanism for filling liquid comprises large liquid measure pump, the first Driving Stepping Motor and the first motor driver; The input connection control device of the first motor driver, output connects the first Driving Stepping Motor; The output shaft of the first Driving Stepping Motor connects large liquid measure pump;
Above-mentioned low consumption of the liquid mechanism for filling liquid comprises low consumption of the liquid pump, the second Driving Stepping Motor and the second motor driver; The input connection control device of the second motor driver, output connects the second Driving Stepping Motor; The output shaft of the second Driving Stepping Motor connects low consumption of the liquid pump;
Host computer connection control device, to export fluid injection instruction to controller, controller controls the operation of the first motor driver or the second motor driver according to fluid injection instruction, thus drive the first Driving Stepping Motor or the second Driving Stepping Motor to run, carry out fluid injection to drive large liquid measure pump or low consumption of the liquid pump.
Embodiment
In embodiment shown in Fig. 1, host computer can adopt computer, and controller can adopt microcontroller chip, and stepper motor driver can adopt existing stepper motor driver, and large liquid measure pump and low consumption of the liquid pump also adopt existing by stepper motor driven topping-up pump.Staff is by upper computer selecting reservoir quantity, fluid injection instruction containing reservoir quantity data is sent to controller by host computer, namely controller starts large liquid measure pump or low consumption of the liquid pump according to reservoir quantity demand estimation, thus sends drive singal to corresponding motor driver.Driving for stepping motor is also prior art.
The reservoir quantity scope of large liquid measure pump is 20ul ~ 200ul, and the reservoir quantity scope of low consumption of the liquid pump is for being less than 20ul.This arranges the requirement for large reservoir quantity and little reservoir quantity of respectively corresponding in-vitro diagnosis apparatus field.
The present embodiment is also provided with alarm output unit, the input connection control device of alarm output unit.When reservoir quantity requires to be greater than 200ul, controller will by alarm output unit output alarm signal, so that staff verifies reservoir quantity requirement.
The present invention is based on the fluid injection control method of said system, comprise the following steps:
Step one, send fluid injection instruction by host computer to controller, fluid injection instruction comprises reservoir quantity data;
Step 2, controller receives fluid injection instruction, and extracts the reservoir quantity data in fluid injection instruction, and judges: as reservoir quantity is less than 20ul, then select low consumption of the liquid mechanism for filling liquid to carry out fluid injection, go to step three; Be less than 200ul as reservoir quantity is greater than 20ul, then select large liquid measure mechanism for filling liquid to carry out fluid injection, go to step four; As reservoir quantity is greater than 200ul, then go to step five;
Step 3, according to reservoir quantity data, and unit step number reservoir quantity during the second Driving Stepping Motor driving low consumption of the liquid pump, calculate the step number to be driven of the second Driving Stepping Motor, then control the second Driving Stepping Motor by the second motor driver and run corresponding step number, the actual reservoir quantity of low consumption of the liquid pump is conformed to the reservoir quantity data in fluid injection instruction;
In this step, the step number to be driven of Driving Stepping Motor can be calculated divided by unit step number reservoir quantity by reservoir quantity data, for prior art, motor driver exports the drive singal of impulse form to stepping motor according to step number to be driven, number of pulses in drive singal is corresponding with driving step number, is also prior art.
Step 4, according to reservoir quantity data, and the unit step number reservoir quantity of the first Driving Stepping Motor when driving large liquid measure pump, calculate the step number to be driven of the second Driving Stepping Motor, then control the first Driving Stepping Motor by the first motor driver and run corresponding step number, the actual reservoir quantity of large liquid measure pump is conformed to the reservoir quantity data in fluid injection instruction;
Step 5, output alarm signal.
Carrying out utilizing chemical luminescence detector device, in in-vitro diagnosis process of the test, utilizing system and method for the present invention, corresponding mechanism for filling liquid can be selected to carry out the interpolation of sample or reagent according to actual reservoir quantity demand, and meet corresponding required precision.Fluid injection efficiency is improved, and also improves efficiency and the result accuracy of in-vitro diagnosis test.
Described in the present invention, concrete case study on implementation is only better case study on implementation of the present invention, is not used for limiting practical range of the present invention.Namely all equivalences done according to the content of the present patent application the scope of the claims change and modify, all should as technology category of the present invention.

Claims (4)

1. a high accuracy fluid injection control system, is characterized in that, comprises large liquid measure mechanism for filling liquid and the low consumption of the liquid mechanism for filling liquid of host computer, controller and corresponding different fluid injection precision;
Above-mentioned large liquid measure mechanism for filling liquid comprises large liquid measure pump, the first Driving Stepping Motor and the first motor driver; The input connection control device of the first motor driver, output connects the first Driving Stepping Motor; The output shaft of the first Driving Stepping Motor connects large liquid measure pump;
Above-mentioned low consumption of the liquid mechanism for filling liquid comprises low consumption of the liquid pump, the second Driving Stepping Motor and the second motor driver; The input connection control device of the second motor driver, output connects the second Driving Stepping Motor; The output shaft of the second Driving Stepping Motor connects low consumption of the liquid pump;
Host computer connection control device, to export fluid injection instruction to controller, controller controls the operation of the first motor driver or the second motor driver according to fluid injection instruction, thus drive the first Driving Stepping Motor or the second Driving Stepping Motor to run, carry out fluid injection to drive large liquid measure pump or low consumption of the liquid pump.
2. high accuracy fluid injection control system according to claim 1, is characterized in that, the reservoir quantity scope of described large liquid measure pump is 20ul ~ 200ul, and the reservoir quantity scope of low consumption of the liquid pump is for being less than 20ul.
3. high accuracy fluid injection control system according to claim 2, it is characterized in that, system also comprises alarm output unit, the input connection control device of alarm output unit.
4., based on the fluid injection control method of the high accuracy fluid injection control system described in Claims 1-4, comprise the following steps:
Step one, send fluid injection instruction by host computer to controller, fluid injection instruction comprises reservoir quantity data;
Step 2, controller receives fluid injection instruction, and extracts the reservoir quantity data in fluid injection instruction, and judges: as reservoir quantity is less than 20ul, then select low consumption of the liquid mechanism for filling liquid to carry out fluid injection, go to step three; Be less than 200ul as reservoir quantity is greater than 20ul, then select large liquid measure mechanism for filling liquid to carry out fluid injection, go to step four; As reservoir quantity is greater than 200ul, then go to step five;
Step 3, according to reservoir quantity data, and unit step number reservoir quantity during the second Driving Stepping Motor driving low consumption of the liquid pump, calculate the step number to be driven of the second Driving Stepping Motor, then control the second Driving Stepping Motor by the second motor driver and run corresponding step number, the actual reservoir quantity of low consumption of the liquid pump is conformed to the reservoir quantity data in fluid injection instruction;
Step 4, according to reservoir quantity data, and the unit step number reservoir quantity of the first Driving Stepping Motor when driving large liquid measure pump, calculate the step number to be driven of the second Driving Stepping Motor, then control the first Driving Stepping Motor by the first motor driver and run corresponding step number, the actual reservoir quantity of large liquid measure pump is conformed to the reservoir quantity data in fluid injection instruction;
Step 5, output alarm signal.
CN201510931891.7A 2015-12-15 2015-12-15 High-accuracy liquid injection control system and method Pending CN105429534A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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Publications (1)

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CN105429534A true CN105429534A (en) 2016-03-23

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020014496A1 (en) * 1996-11-20 2002-02-07 Cline David J. Method and apparatus for accurately dispensing liquids and solids
CN101082629A (en) * 2007-07-04 2007-12-05 南京大学 Liquid automatically quantificationally continuously sampling device
CN201650685U (en) * 2010-01-29 2010-11-24 上海迅达医疗仪器有限公司 Mechanical-electrical integration peristaltic pump
CN103926135A (en) * 2014-05-09 2014-07-16 欧蒙医学诊断(中国)有限公司 Automatic dilution device and method
CN104033348A (en) * 2014-06-09 2014-09-10 四川大学 Digital quantitative continuous liquid injection pump
CN205657615U (en) * 2015-12-15 2016-10-19 苏州长光华医生物医学工程有限公司 Liquid control system is annotated to high accuracy

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020014496A1 (en) * 1996-11-20 2002-02-07 Cline David J. Method and apparatus for accurately dispensing liquids and solids
CN101082629A (en) * 2007-07-04 2007-12-05 南京大学 Liquid automatically quantificationally continuously sampling device
CN201650685U (en) * 2010-01-29 2010-11-24 上海迅达医疗仪器有限公司 Mechanical-electrical integration peristaltic pump
CN103926135A (en) * 2014-05-09 2014-07-16 欧蒙医学诊断(中国)有限公司 Automatic dilution device and method
CN104033348A (en) * 2014-06-09 2014-09-10 四川大学 Digital quantitative continuous liquid injection pump
CN205657615U (en) * 2015-12-15 2016-10-19 苏州长光华医生物医学工程有限公司 Liquid control system is annotated to high accuracy

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Application publication date: 20160323

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