CN105395893A - 一种清咽口服液及其制备方法 - Google Patents
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- 229940100688 oral solution Drugs 0.000 title abstract 4
- 239000003814 drug Substances 0.000 claims abstract description 15
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 6
- 238000009835 boiling Methods 0.000 claims abstract description 3
- 239000007788 liquid Substances 0.000 claims description 16
- 230000001476 alcoholic effect Effects 0.000 claims description 3
- 235000009508 confectionery Nutrition 0.000 claims description 3
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims description 3
- 235000010234 sodium benzoate Nutrition 0.000 claims description 3
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- 230000001954 sterilising effect Effects 0.000 claims description 3
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- 230000000694 effects Effects 0.000 abstract description 5
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- 230000008961 swelling Effects 0.000 abstract description 3
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- 235000011477 liquorice Nutrition 0.000 abstract 1
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- A61K2236/30—Extraction of the material
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Abstract
本发明涉及一种清咽口服液及其制备方法，本发明选用南沙参、石斛、陈皮、玄参、生地、金银花、枳壳、黄芩、麦冬、薄荷、桔梗、甘草共十二味中草药经二次高压水煎、过滤、减压压缩、醇提、煮沸等工序精制而成，本发明中各药物组分选配合理，制备方法简单，具有清热解毒、消肿止痛、清热利肺、滋阴利咽之功效。
Description
本发明涉及一种清咽口服液及其制备方法。
目前临床用于治疗咽喉肿痛的清热制剂较多，而大多数复配中草药制剂存在着各组分配伍不好，疗效不显著等缺点。
本发明的目的在于提供一种清咽口服液及其制备方法。以克服现有技术之不足。
本发明的药物组成是(单位重量份)：
本发明的制备方法是：
将上述药物洗净，经高压水煎两次，第一次加入为上述药物组分3—8倍重量的水，煎煮1.5—2小时，第二次加入上述药物组分3—5倍重量的水煎0.5一1.5小时，然后将两次药液合并过滤。减压浓缩至相对密度为1.15—1.2，放冷后在药液中加入,85—90％的乙醇溶液。使混合液含醇达55—60％，搅拌10分钟，静置16—24小时，将上清液滤至洁净容器内。回收乙醇使药液含醇量低于10％，加入甜矫味剂及适量苯甲酸钠，煮沸15分钟后加蒸馏水至混合液体积为30ml，灌装后经100℃、30分钟灭菌即可。高压水煎时压力为1.5个大气压。
以下结合实施例对本发明作进一步描述；
实施例1：
制备方法是：
称取上述药材洗净，经1.5个大气压水煎两次，第一次加6倍于上述药物重量的水煎1.5小时。第二次加4倍于上述药物重量的水煎1小时，然后将两次药液合并过滤，减压浓缩至相对密度为1.2，放冷，加入90％乙醇溶液，使溶液含醇量达60％，搅拌10分钟，静置20小时后将上清液滤至洁净容器内，回收乙醇，使药液含醇量达8％，加入甜矫味剂及苯甲酸钠适量，煮沸15分钟，加蒸馏水至30ml。灌装后经100℃、30分钟灭菌即可。
实施例2：
制备方法同实施例1。
本发明中各药物组分作用是：
南沙参、地生、麦冬、玄参、石斛等中药有养阴、清热、降火，并有清肺益胃作用，薄荷、枳壳又具疏风、破气、散热、消积之功。金银花、黄岑具清热解毒、泻火、澡湿之功。桔醒具止咳、化痰之作用，甘草解毒、调和诸药。
本发明所取得的技术进步及实质性特点在于：
本发明所选用各药物组分适当，配伍合理.制备方法简便，具有清热解毒、消肿止痛、清热利肺、滋阴利咽之功能。
Claims (3)
1.清咽口服液，其特征在于其药物组成是(单位重量份)：
2.根据权利要求1所述的清咽口服液的制备方法，其特征在于将上述药物洗净，经高压水煎两次，第一次加入为上述药物组分3—8倍重量的水，煎煮1.5—2时.第二次加入上述药物组分3—5倍重量的水煎0.5—15小时，然后将两次药液合并过滤，减压浓缩至相对密度为1015—1.2，放冷后在药液中加入85—90％的乙醇溶液，使混合液含醇达55—60％，搅拌10分钟，静置16—24小时，将上清液滤至洁净容器内，回收乙醇使药液含醇量低于10％，加入甜矫味剂及适量苯甲酸钠，煮沸15分钟后加蒸馏水至混合液体积为30ml，灌装后经100℃、30分钟灭菌即可。
3.根据权利要求2所述的清咽口服液的制备方法，其特征在于高压水煎时压力为1.5个大气压。
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105748882A (zh) * | 2016-03-23 | 2016-07-13 | 林启东 | 一种利咽中药组合物及其制备方法 |
| CN110179945A (zh) * | 2019-07-12 | 2019-08-30 | 戚春直 | 一种清咽益胃茶及其制备方法 |
-
2015
- 2015-12-23 CN CN201510988348.0A patent/CN105395893A/zh active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105748882A (zh) * | 2016-03-23 | 2016-07-13 | 林启东 | 一种利咽中药组合物及其制备方法 |
| CN110179945A (zh) * | 2019-07-12 | 2019-08-30 | 戚春直 | 一种清咽益胃茶及其制备方法 |
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