CN105381158A - 一种治疗肝硬化的中药组合物 - Google Patents
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Abstract
本发明公开了一种治疗肝硬化的中药组合物，由以下重量份的中药原料制成：矮紫堇33-40份，穿山龙21-34份，洋金花13-27份，穿破石10-19份，洪连5-12份，千斤拔3-11份，赤芍3-8份，蒲桃2-7份。与现有技术相比，本发明的主要优点在于，本发明采用的是地道药材，采用纯中草药，没有毒副作用，君臣佐使，配伍合理，作用相互协调，切中病机，在治疗肝硬化中起到的显著的作用。
Description
技术领域
本发明涉及一种治疗肝硬化的中药组合物。
背景技术
肝硬化、肝腹水一是人们口中常见的疾病，引起的原因可由多种原因引起，主要是由于乙型肝炎、丙型肝炎、脂肪肝等长期损害肝脏引起，肝脏呈进行性、弥漫性、纤维性病变。肝硬化临床以肝功能受损与门脉高压为主要表现。依据中医理论认为，肝脏气血淤滞，经络闭塞，津液不能输布以营养肝脏，肝脏失养，故肝硬化，而成癥结，故出现：饮食减少、不消化、食后腹胀、恶心、精神疲倦、消瘦、心神不安、失眠、两肋胀痛、肝手掌、黄疸、小便黄等现象肝硬化在我国大多数为肝炎后肝硬化，少部分为酒精性肝硬化和血吸虫性肝硬化。病理组织学上有广泛的肝细胞坏死、残存肝细胞结节性再生、结缔组织增生与纤维隔形成，导致肝小叶结构破坏和假小叶形成，肝脏逐渐变形、变硬而发展为肝硬化。早期由于肝脏代偿功能较强可无明显症状，后期则以肝功能损害和门脉高压为主要表现，并有多系统受累，晚期常出现上消化道出血、肝性脑病、继发感染、脾功能亢进、腹水、癌变等并发症。目前，治疗肝硬化没有什么特效药，基本都是从中医角度，多用疏肝解郁，清热毒，活血祛瘀，软坚散结，清热利湿药物加之服用西药抗肝炎病毒以及保肝药物治疗。如采用拉米规定、恩替卡韦、利巴韦林和干扰素等抗病毒药物治疗，再用维生素K1注射液，还原谷胱甘肽，5％葡萄糖注射液加入维生素C、氯化钾等保肝，或内服水飞蓟宾胶囊，茴三硫等以消肝中之炎和利胆退黄，但这些治疗其效果不理想，治愈慢，中西医结合治疗，往往能收到较好的效果，但是治疗费用较高。肝硬化已经成为严重影响人们的身体健康和生活质量的最常见的疾病之一，在临床上对于肝硬化的治疗原则就是早发现早治疗，同时要通过综合性的治疗方法达到治疗肝硬化的目的工，历年来西医以护肝清毒，补蛋白，抽腹水为最佳治疗法则，虽近期疗效十分乐观，但远期疗效并不理想。发明内容
本发明所要解决的技术问题是：提供一种治疗效果的中药组合物，无毒副作用，反复率较低。为解决上述技术问题，本发明采用的技术方案是：
本发明提供的一种治疗肝硬化的中药组合物，由以下重量份的中药原料制成：矮紫堇33-40份，穿山龙21-34份，洋金花13-27份，穿破石10-19份，洪连5-12份，千斤拔3-11份，赤芍3-8份，蒲桃2-7份。
优选的，本发明提供的中药由以下重量份的中药原料制成：矮紫堇37份，穿山龙28份，洋金花20份，穿破石13份，洪连9份，千斤拔6份，赤芍5份，蒲桃4份。
用法用量：将上述中药用温水浸泡10分钟后，用武火煮沸后再用文火煮30分钟，取药液150毫升，再加水二煎，将两次药液混合后过滤，分两次服用。每天两次，饭后服用。
疗程：15天为一疗程，需服用2-5疗程。
本发明的有益效果：
与现有技术相比，本发明的主要优点在于，本发明采用的是地道药材，采用纯中草药，没有毒副作用，君臣佐使，配伍合理，作用相互协调，切中病机，在治疗肝硬化中起到的显著的作用。
具体实施方式
实施例1
本实施例提供的一种治疗肝硬化的中药组合物，由以下重量份的中药原料制成：矮紫堇37份，穿山龙28份，洋金花20份，穿破石13份，洪连9份，千斤拔6份，赤芍5份，蒲桃4份。
临床实验数据：
1、一般资料：发明人2012年-2015年月间共收集了200例肝硬化患者，其中，年龄25岁-55岁，病情0.5年-2年。
2、试验方法：(1)随机分为：治疗组100例，对照组100例。两组年龄等资料无显著性差异，具有可比性。(2)治疗组口服本发明按照具体实施例1的中药，按照上述的用法用量服用；对照组服用恩替卡韦，按照说明书服用，疗程2个月。
3、疗效标准及治疗结果：
3.1疗效标准：痊愈：肝硬化的临床症状全部消失。好转：肝硬化的临床症状减轻，病情得到控制。无效：肝硬化的临床症状无明显好转或加重。以痊愈和好转计算有效率。3.2、治疗统计结果如下：
疗效比较
实验组：痊愈87例，好转10例，无效3例；
对照组：痊愈60例，好转13例，无效27例；
对以上治愈的个体经过1年的回访，没有发现复发的个体。此可见，采用本发明的组方制得的药物能够安全有效治疗肝硬化。
典型病例：
病例1：周某，女，52岁，患者初次感觉胃部不适，经医院诊断，该患者为早期肝硬化，后经过服用本发明实施例1的中药，1个疗程之后，体力逐渐恢复，并能够进行劳动，继续服3个疗程，经医院诊断，患者肝细胞阻塞消失，肝功能达到正常人水平，没有发生复发。病例2：朱某，男，44岁，经常酗酒导致肝细胞硬化，服用本发明实施例1的中药进行治疗，1个疗程之后，自觉身体恢复正常，体力增加，并能够进行劳动，继续服3个疗程，经医院诊断，患者肝硬化症状消失，肝功能达到正常人水平，没有发生复发。
Claims (2)
1.一种治疗肝硬化的中药组合物，其特征在于，由以下重量份的中药原料制成：矮紫堇33-40份，穿山龙21-34份，洋金花13-27份，穿破石10-19份，洪连5-12份，千斤拔3-11份，赤芍3-8份，蒲桃2-7份。
2.根据权利要求1所述的中药组合物，其特征在于，由以下重量份的中药原料制成：矮紫堇37份，穿山龙28份，洋金花20份，穿破石13份，洪连9份，千斤拔6份，赤芍5份，蒲桃4份。
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