CN105343614A - 治疗慢性鼻窦炎的中药组合物 - Google Patents

治疗慢性鼻窦炎的中药组合物 Download PDF

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CN105343614A
CN105343614A CN201510859113.1A CN201510859113A CN105343614A CN 105343614 A CN105343614 A CN 105343614A CN 201510859113 A CN201510859113 A CN 201510859113A CN 105343614 A CN105343614 A CN 105343614A
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王建文
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Abstract

本发明涉及一种药物配方领域,具体地说是一种治疗慢性鼻窦炎的中药组合物,其特征在于由如下重份的原料药制成,辛夷花13~18,泡囊草13~18,伤寒草17~23,千里光17~23,金丝草12~16,大血藤3~7,蓼实3~7,水莎草18~25,白附子13~17,蔓荆子28~34,石菖蒲10~14,鹅不食草14~16,路路通14~16,赤芍8~11,皂角刺10~13,蓁艽28~34,密蒙花8~12,鱼腥草8~12,紫金牛13~17,赶山鞭16~20,大发表7~10,将上述21味原料药混和后用水浸泡,煎熬后去渣得滤液。本发明用于治疗慢性鼻窦炎,成本低、没有明显毒副作用,治疗有效率较高。

Description

治疗慢性鼻窦炎的中药组合物
技术领域
本发明涉及一种中成药制剂,具体地说是一种治疗慢性鼻窦炎的中药组合物。
背景技术
众所周知,性鼻窦炎是临床常见病、多发病,主要表现为鼻塞、流涕、头晕、头闷痛、嗅觉减退、注意力不集中、记忆力下降等症状,严重影响患者学习、生活。慢性鼻窦炎的发病是多种致病因素共同作用的结果,包括局部致病菌感染、机体变态反应性增高、微循环障碍口鼻道复合体畸形及全身免疫力低下等,导致鼻粘膜水肿、增厚及息肉样变、囊性改变,或纤维组织增生、血管阻塞,腺体萎缩,粘膜萎缩。
西医主要为对症治疗如:局部滴药(常用血管收缩剂滴鼻和皮质类固醇激素,改善鼻腔通气)和引流;在正规的保守治疗无效后方可采用鼻腔病变手术以解除中鼻道及其附近区域的阻塞,改善鼻窦引流和通气,促进鼻窦炎症的消退,如中鼻甲、下鼻甲部分切除术和鼻中隔偏曲矫正术等。西医治疗本病虽有一定疗效,但存在易复发,西药副作用较大,手术治疗患者往往不易接受等问题。
发明内容
本发明的目的就是为了克服上述现有的技术不足,提供一种治疗慢性鼻窦炎的中药组合物,具有清热排脓、解表清里、通窍利湿,提高机体免疫力的功效,成本低,疗效显著,无毒副作用。
本发明解决上述技术问题采用的技术方案是:一种治疗慢性鼻窦炎的中药组合物,其特征在于由如下重份的原料药制成,辛夷花13~18,泡囊草13~18,伤寒草17~23,千里光17~23,金丝草12~16,大血藤3~7,蓼实3~7,水莎草18~25,白附子13~17,蔓荆子28~34,石菖蒲10~14,鹅不食草14~16,路路通14~16,赤芍8~11,皂角刺10~13,蓁艽28~34,密蒙花8~12,鱼腥草8~12,紫金牛13~17,赶山鞭16~20,大发表7~10,将上述21味原料药混和后用水浸泡,煎熬后去渣得滤液。
本发明有益效果是,具有清热排脓、解表清里、通窍利湿,提高机体免疫力的功效,成本低,疗效显著,无毒副作用。
具体实施方式
下面结合实施例对本发明作进一步的描述:
实施例1:
采用辛夷花、泡囊草、伤寒草、千里光、金丝草、大血藤、蓼实、水莎草、白附子、蔓荆子、石菖蒲、鹅不食草、路路通、赤芍、皂角刺、蓁艽、密蒙花、鱼腥草、紫金牛、赶山鞭、大发表,为原料药制备而成,其组分(以重量份计)为:辛夷花15、泡囊草15、伤寒草20、千里光18、金丝草14、大血藤5、蓼实6、水莎草22、白附子15、蔓荆子31、石菖蒲13、鹅不食草15、路路通15、赤芍10、皂角刺12、蓁艽30、密蒙花11、鱼腥草10、紫金牛15、赶山鞭17、大发表9,取上述21味原料药总重量为270克,在室温下加净化水1000毫升,浸泡5-6小时,然后用武火煮沸文火煎熬100-120分钟左右,去渣得滤液120毫升,药渣再加水300毫升,煎熬30-40分钟,去渣得滤液80毫升,共得200毫升药汁,即制得本发明的中药汤剂,空腹服200ml。
本发明辛夷花祛风寒,通鼻窍。用于风寒头痛,鼻塞,鼻渊,鼻流浊涕;泡囊草清热解毒。主痈肿疮毒,咽喉肿毒,鼻渊,聤耳;伤寒草清热解毒,消肿拔毒,排脓;千里光清热解毒,明目退翳,杀虫止痒。主流感,上呼吸道感染,肺炎,急性扁桃体炎;金丝草有清凉散热,解毒、利尿通淋之药效;大血藤具有清热解毒,活血通络,祛风止痉的作用;蓼实治吐泻腹痛,症积痞胀,水气浮肿,痈肿疮疡,瘰疬;水莎草止咳化痰。主慢性支气管炎;白附子具有祛风痰,定惊搐,解毒散结,止痛的功效;蔓荆子疏散风热,清利头目,除湿处关节。常用于外感头痛,偏正头风;石菖蒲化湿开胃,开窍豁痰,醒神益智;鹅不食草具有发散风寒,通鼻窍,止咳,解毒,止痒等功效;路路通用于关节痹痛,麻木痉挛,水肿胀满;赤芍有清热凉血,活血祛瘀的功效;皂角刺具有消肿托毒,排脓,杀虫之功效。常用于痈疽初起或脓成不溃;蓁艽治风寒痹湿,通身挛急,虚劳骨蒸;密蒙花用于目赤肿痛,多泪羞明,目生翳膜,肝虚目暗,视物昏花;鱼腥草能清热解毒、消肿疗疮、利尿除湿、清热止痢;紫金牛止咳化痰,祛风解毒,活血止痛;赶山鞭止血,镇痛,通乳。用于咯血,吐血,子宫出血,风湿关节痛;大发表利五脏、明耳目、去热风、止热疟、活血平胃。将这些药物组合使得各药物功效产生协同作用,从而有效地共奏宣肺散邪、清泻肝火、凉血活血、散结排脓之效。
本发明各原料还可按下表所列比例(重量份)混合的实施例来实现。其加工工艺与实施例1相同。
下面结合我院进行的临床试验对本发明作进一步、详细地描述:
1、一般资料:所有患者均来自2013年11月至2015年4月在门诊耳鼻喉科就诊的患者,诊断标准参照《实用耳喉鼻科学》中“慢性鼻窦炎”诊断标准拟定。(1)症状:鼻塞、流脓、嗅觉减退或者消失,且多伴有头痛、头晕、头胀。(2)体征:鼻道中有脓性分泌物流出,鼻甲肥大、水肿或者息肉样改变。(3)辅助检查:所有病例均摄柯、华氏X线片检查显示符合慢性鼻窦炎性改变。排除鼻窦其它性质病变。符合以上诊断标准的鼻窦炎患者共100例,其中男60例,女40例,年龄21-56岁,病程2-13年。随机分为:治疗组50例,对照组50例。两组年龄、病情等资料差异均无统计学意义(P>0.05),具有可比性。
2、治疗方法:
治疗组:口服本发明实施例1所述的中药汤剂,每日早上空腹服200ml,7天为一个疗程,服用1-3个疗程,对照组服用抗生素或磺胺类药物。
3、疗程评定标准:
痊愈:症状完全消失无复发,无任何不适症状;
显效:症状消失,一年以内无复发;
有效:症状明显减轻,或部分症状消失,需继续治疗;
无效:症状未有任何改善,甚而有加重之趋势。
4、治疗结果
表1两组治疗效果比较
组别 例数 治愈 显效 有效 无效 有效率
治疗组 50 15 23 10 2 96%
对照组 50 11 18 7 14 72%
典型病例:
常某,女,41岁,患鼻窦炎有三年,期间进行了多次治疗,服用了大量口服药物,均未治愈。曾经进行了手术治疗,但两年后又复发,后服用本实施例1制备的中药汤剂,每日一剂。服药一周后感觉头痛有所减轻,继续服药两周后感觉呼吸顺畅了,巩固治疗一周后痊愈,至今无复发。
胡某,男,22岁,因为学习长期熬夜,而由感冒导致鼻窦炎症,吃了不少药物,病情时好时坏。服用本实施例1制备的中药汤剂,每日一剂,三周后痊愈,至今无复发。
许某,女,53岁,近年来反复鼻塞流鼻涕,伴嗅觉减退,头昏,头胀痛,以前额为主,经多方治疗症状曾一度缓解不能根治,每遇感冒或疲劳则诸症加重,服用本发明实施例1制备的中药汤剂,连服30天后诸症明显治愈,半年后随访未见复发。

Claims (1)

1.一种治疗慢性鼻窦炎的中药组合物,其特征在于:由如下重份的原料药制成,辛夷花13~18,泡囊草13~18,伤寒草17~23,千里光17~23,金丝草12~16,大血藤3~7,蓼实3~7,水莎草18~25,白附子13~17,蔓荆子28~34,石菖蒲10~14,鹅不食草14~16,路路通14~16,赤芍8~11,皂角刺10~13,蓁艽28~34,密蒙花8~12,鱼腥草8~12,紫金牛13~17,赶山鞭16~20,大发表7~10,将上述21味原料药混和后用水浸泡,煎熬后去渣得滤液。
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