CN105343614A - 治疗慢性鼻窦炎的中药组合物 - Google Patents
治疗慢性鼻窦炎的中药组合物 Download PDFInfo
- Publication number
- CN105343614A CN105343614A CN201510859113.1A CN201510859113A CN105343614A CN 105343614 A CN105343614 A CN 105343614A CN 201510859113 A CN201510859113 A CN 201510859113A CN 105343614 A CN105343614 A CN 105343614A
- Authority
- CN
- China
- Prior art keywords
- parts
- herba
- chinese medicine
- medicine composition
- traditional chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 35
- 239000000203 mixture Substances 0.000 title claims abstract description 9
- 230000001684 chronic effect Effects 0.000 title abstract 3
- 241001643642 Viticis Species 0.000 claims abstract description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 4
- 241000628997 Flos Species 0.000 claims description 10
- 229940079593 drug Drugs 0.000 claims description 10
- 206010009137 Chronic sinusitis Diseases 0.000 claims description 8
- 208000027157 chronic rhinosinusitis Diseases 0.000 claims description 8
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 claims description 5
- 239000000706 filtrate Substances 0.000 claims description 4
- 239000002893 slag Substances 0.000 claims description 4
- 238000005303 weighing Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 12
- 239000002994 raw material Substances 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 235000013399 edible fruits Nutrition 0.000 abstract 2
- 241000471262 Ardisia japonica Species 0.000 abstract 1
- 241000758794 Asarum Species 0.000 abstract 1
- 241001113925 Buddleja Species 0.000 abstract 1
- 241001633683 Centipeda <firmicute> Species 0.000 abstract 1
- 240000001689 Cyanthillium cinereum Species 0.000 abstract 1
- 241000501743 Gentiana macrophylla Species 0.000 abstract 1
- 235000013717 Houttuynia Nutrition 0.000 abstract 1
- 240000000691 Houttuynia cordata Species 0.000 abstract 1
- 241000782604 Hypericum attenuatum Species 0.000 abstract 1
- 241000208682 Liquidambar Species 0.000 abstract 1
- 235000006552 Liquidambar styraciflua Nutrition 0.000 abstract 1
- 241000218378 Magnolia Species 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 1
- 240000000275 Persicaria hydropiper Species 0.000 abstract 1
- 235000017337 Persicaria hydropiper Nutrition 0.000 abstract 1
- 241000388479 Physochlaina Species 0.000 abstract 1
- 240000003705 Senecio vulgaris Species 0.000 abstract 1
- 241000746716 Typhonium Species 0.000 abstract 1
- 240000002895 Vicia hirsuta Species 0.000 abstract 1
- 240000008042 Zea mays Species 0.000 abstract 1
- 235000007244 Zea mays Nutrition 0.000 abstract 1
- 230000009194 climbing Effects 0.000 abstract 1
- 244000082735 tidal marsh flat sedge Species 0.000 abstract 1
- 231100000614 poison Toxicity 0.000 description 10
- 208000024891 symptom Diseases 0.000 description 8
- 239000003440 toxic substance Substances 0.000 description 8
- 201000009890 sinusitis Diseases 0.000 description 7
- 208000002193 Pain Diseases 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 230000036407 pain Effects 0.000 description 5
- 244000052769 pathogen Species 0.000 description 5
- 230000001737 promoting effect Effects 0.000 description 5
- 206010062717 Increased upper airway secretion Diseases 0.000 description 4
- 206010030113 Oedema Diseases 0.000 description 4
- 210000003128 head Anatomy 0.000 description 4
- 208000026435 phlegm Diseases 0.000 description 4
- 206010002653 Anosmia Diseases 0.000 description 3
- 206010007247 Carbuncle Diseases 0.000 description 3
- 206010011224 Cough Diseases 0.000 description 3
- 206010019233 Headaches Diseases 0.000 description 3
- 206010050515 Hyposmia Diseases 0.000 description 3
- 206010039101 Rhinorrhoea Diseases 0.000 description 3
- 238000007599 discharging Methods 0.000 description 3
- 208000002173 dizziness Diseases 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 231100000869 headache Toxicity 0.000 description 3
- 235000019559 hyposmia Nutrition 0.000 description 3
- 230000036039 immunity Effects 0.000 description 3
- 230000001717 pathogenic effect Effects 0.000 description 3
- 206010010904 Convulsion Diseases 0.000 description 2
- 206010028748 Nasal obstruction Diseases 0.000 description 2
- 241000475481 Nebula Species 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000004438 eyesight Effects 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 208000010753 nasal discharge Diseases 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 210000001331 nose Anatomy 0.000 description 2
- 210000003695 paranasal sinus Anatomy 0.000 description 2
- 244000045947 parasite Species 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 235000019615 sensations Nutrition 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 206010003694 Atrophy Diseases 0.000 description 1
- 206010006458 Bronchitis chronic Diseases 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 206010010726 Conjunctival oedema Diseases 0.000 description 1
- 206010057315 Daydreaming Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010020880 Hypertrophy Diseases 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 206010067994 Mucosal atrophy Diseases 0.000 description 1
- 206010034960 Photophobia Diseases 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 208000036071 Rhinorrhea Diseases 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 206010046306 Upper respiratory tract infection Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 206010001093 acute tonsillitis Diseases 0.000 description 1
- 239000003470 adrenal cortex hormone Substances 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 208000007451 chronic bronchitis Diseases 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 210000001061 forehead Anatomy 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 208000025938 nasal cavity disease Diseases 0.000 description 1
- 210000002850 nasal mucosa Anatomy 0.000 description 1
- 210000000492 nasalseptum Anatomy 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000010287 polarization Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 201000003068 rheumatic fever Diseases 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000002636 symptomatic treatment Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 210000001944 turbinate Anatomy 0.000 description 1
- 239000005526 vasoconstrictor agent Substances 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 239000002351 wastewater Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/483—Gleditsia (locust)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/89—Cyperaceae (Sedge family)
- A61K36/8905—Cyperus (flatsedge)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明涉及一种药物配方领域,具体地说是一种治疗慢性鼻窦炎的中药组合物,其特征在于由如下重份的原料药制成,辛夷花13~18,泡囊草13~18,伤寒草17~23,千里光17~23,金丝草12~16,大血藤3~7,蓼实3~7,水莎草18~25,白附子13~17,蔓荆子28~34,石菖蒲10~14,鹅不食草14~16,路路通14~16,赤芍8~11,皂角刺10~13,蓁艽28~34,密蒙花8~12,鱼腥草8~12,紫金牛13~17,赶山鞭16~20,大发表7~10,将上述21味原料药混和后用水浸泡,煎熬后去渣得滤液。本发明用于治疗慢性鼻窦炎,成本低、没有明显毒副作用,治疗有效率较高。
Description
技术领域
本发明涉及一种中成药制剂,具体地说是一种治疗慢性鼻窦炎的中药组合物。
背景技术
众所周知,性鼻窦炎是临床常见病、多发病,主要表现为鼻塞、流涕、头晕、头闷痛、嗅觉减退、注意力不集中、记忆力下降等症状,严重影响患者学习、生活。慢性鼻窦炎的发病是多种致病因素共同作用的结果,包括局部致病菌感染、机体变态反应性增高、微循环障碍口鼻道复合体畸形及全身免疫力低下等,导致鼻粘膜水肿、增厚及息肉样变、囊性改变,或纤维组织增生、血管阻塞,腺体萎缩,粘膜萎缩。
西医主要为对症治疗如:局部滴药(常用血管收缩剂滴鼻和皮质类固醇激素,改善鼻腔通气)和引流;在正规的保守治疗无效后方可采用鼻腔病变手术以解除中鼻道及其附近区域的阻塞,改善鼻窦引流和通气,促进鼻窦炎症的消退,如中鼻甲、下鼻甲部分切除术和鼻中隔偏曲矫正术等。西医治疗本病虽有一定疗效,但存在易复发,西药副作用较大,手术治疗患者往往不易接受等问题。
发明内容
本发明的目的就是为了克服上述现有的技术不足,提供一种治疗慢性鼻窦炎的中药组合物,具有清热排脓、解表清里、通窍利湿,提高机体免疫力的功效,成本低,疗效显著,无毒副作用。
本发明解决上述技术问题采用的技术方案是:一种治疗慢性鼻窦炎的中药组合物,其特征在于由如下重份的原料药制成,辛夷花13~18,泡囊草13~18,伤寒草17~23,千里光17~23,金丝草12~16,大血藤3~7,蓼实3~7,水莎草18~25,白附子13~17,蔓荆子28~34,石菖蒲10~14,鹅不食草14~16,路路通14~16,赤芍8~11,皂角刺10~13,蓁艽28~34,密蒙花8~12,鱼腥草8~12,紫金牛13~17,赶山鞭16~20,大发表7~10,将上述21味原料药混和后用水浸泡,煎熬后去渣得滤液。
本发明有益效果是,具有清热排脓、解表清里、通窍利湿,提高机体免疫力的功效,成本低,疗效显著,无毒副作用。
具体实施方式
下面结合实施例对本发明作进一步的描述:
实施例1:
采用辛夷花、泡囊草、伤寒草、千里光、金丝草、大血藤、蓼实、水莎草、白附子、蔓荆子、石菖蒲、鹅不食草、路路通、赤芍、皂角刺、蓁艽、密蒙花、鱼腥草、紫金牛、赶山鞭、大发表,为原料药制备而成,其组分(以重量份计)为:辛夷花15、泡囊草15、伤寒草20、千里光18、金丝草14、大血藤5、蓼实6、水莎草22、白附子15、蔓荆子31、石菖蒲13、鹅不食草15、路路通15、赤芍10、皂角刺12、蓁艽30、密蒙花11、鱼腥草10、紫金牛15、赶山鞭17、大发表9,取上述21味原料药总重量为270克,在室温下加净化水1000毫升,浸泡5-6小时,然后用武火煮沸文火煎熬100-120分钟左右,去渣得滤液120毫升,药渣再加水300毫升,煎熬30-40分钟,去渣得滤液80毫升,共得200毫升药汁,即制得本发明的中药汤剂,空腹服200ml。
本发明辛夷花祛风寒,通鼻窍。用于风寒头痛,鼻塞,鼻渊,鼻流浊涕;泡囊草清热解毒。主痈肿疮毒,咽喉肿毒,鼻渊,聤耳;伤寒草清热解毒,消肿拔毒,排脓;千里光清热解毒,明目退翳,杀虫止痒。主流感,上呼吸道感染,肺炎,急性扁桃体炎;金丝草有清凉散热,解毒、利尿通淋之药效;大血藤具有清热解毒,活血通络,祛风止痉的作用;蓼实治吐泻腹痛,症积痞胀,水气浮肿,痈肿疮疡,瘰疬;水莎草止咳化痰。主慢性支气管炎;白附子具有祛风痰,定惊搐,解毒散结,止痛的功效;蔓荆子疏散风热,清利头目,除湿处关节。常用于外感头痛,偏正头风;石菖蒲化湿开胃,开窍豁痰,醒神益智;鹅不食草具有发散风寒,通鼻窍,止咳,解毒,止痒等功效;路路通用于关节痹痛,麻木痉挛,水肿胀满;赤芍有清热凉血,活血祛瘀的功效;皂角刺具有消肿托毒,排脓,杀虫之功效。常用于痈疽初起或脓成不溃;蓁艽治风寒痹湿,通身挛急,虚劳骨蒸;密蒙花用于目赤肿痛,多泪羞明,目生翳膜,肝虚目暗,视物昏花;鱼腥草能清热解毒、消肿疗疮、利尿除湿、清热止痢;紫金牛止咳化痰,祛风解毒,活血止痛;赶山鞭止血,镇痛,通乳。用于咯血,吐血,子宫出血,风湿关节痛;大发表利五脏、明耳目、去热风、止热疟、活血平胃。将这些药物组合使得各药物功效产生协同作用,从而有效地共奏宣肺散邪、清泻肝火、凉血活血、散结排脓之效。
本发明各原料还可按下表所列比例(重量份)混合的实施例来实现。其加工工艺与实施例1相同。
下面结合我院进行的临床试验对本发明作进一步、详细地描述:
1、一般资料:所有患者均来自2013年11月至2015年4月在门诊耳鼻喉科就诊的患者,诊断标准参照《实用耳喉鼻科学》中“慢性鼻窦炎”诊断标准拟定。(1)症状:鼻塞、流脓、嗅觉减退或者消失,且多伴有头痛、头晕、头胀。(2)体征:鼻道中有脓性分泌物流出,鼻甲肥大、水肿或者息肉样改变。(3)辅助检查:所有病例均摄柯、华氏X线片检查显示符合慢性鼻窦炎性改变。排除鼻窦其它性质病变。符合以上诊断标准的鼻窦炎患者共100例,其中男60例,女40例,年龄21-56岁,病程2-13年。随机分为:治疗组50例,对照组50例。两组年龄、病情等资料差异均无统计学意义(P>0.05),具有可比性。
2、治疗方法:
治疗组:口服本发明实施例1所述的中药汤剂,每日早上空腹服200ml,7天为一个疗程,服用1-3个疗程,对照组服用抗生素或磺胺类药物。
3、疗程评定标准:
痊愈:症状完全消失无复发,无任何不适症状;
显效:症状消失,一年以内无复发;
有效:症状明显减轻,或部分症状消失,需继续治疗;
无效:症状未有任何改善,甚而有加重之趋势。
4、治疗结果
表1两组治疗效果比较
组别 | 例数 | 治愈 | 显效 | 有效 | 无效 | 有效率 |
治疗组 | 50 | 15 | 23 | 10 | 2 | 96% |
对照组 | 50 | 11 | 18 | 7 | 14 | 72% |
典型病例:
常某,女,41岁,患鼻窦炎有三年,期间进行了多次治疗,服用了大量口服药物,均未治愈。曾经进行了手术治疗,但两年后又复发,后服用本实施例1制备的中药汤剂,每日一剂。服药一周后感觉头痛有所减轻,继续服药两周后感觉呼吸顺畅了,巩固治疗一周后痊愈,至今无复发。
胡某,男,22岁,因为学习长期熬夜,而由感冒导致鼻窦炎症,吃了不少药物,病情时好时坏。服用本实施例1制备的中药汤剂,每日一剂,三周后痊愈,至今无复发。
许某,女,53岁,近年来反复鼻塞流鼻涕,伴嗅觉减退,头昏,头胀痛,以前额为主,经多方治疗症状曾一度缓解不能根治,每遇感冒或疲劳则诸症加重,服用本发明实施例1制备的中药汤剂,连服30天后诸症明显治愈,半年后随访未见复发。
Claims (1)
1.一种治疗慢性鼻窦炎的中药组合物,其特征在于:由如下重份的原料药制成,辛夷花13~18,泡囊草13~18,伤寒草17~23,千里光17~23,金丝草12~16,大血藤3~7,蓼实3~7,水莎草18~25,白附子13~17,蔓荆子28~34,石菖蒲10~14,鹅不食草14~16,路路通14~16,赤芍8~11,皂角刺10~13,蓁艽28~34,密蒙花8~12,鱼腥草8~12,紫金牛13~17,赶山鞭16~20,大发表7~10,将上述21味原料药混和后用水浸泡,煎熬后去渣得滤液。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510859113.1A CN105343614A (zh) | 2015-11-23 | 2015-11-23 | 治疗慢性鼻窦炎的中药组合物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510859113.1A CN105343614A (zh) | 2015-11-23 | 2015-11-23 | 治疗慢性鼻窦炎的中药组合物 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN105343614A true CN105343614A (zh) | 2016-02-24 |
Family
ID=55319773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510859113.1A Pending CN105343614A (zh) | 2015-11-23 | 2015-11-23 | 治疗慢性鼻窦炎的中药组合物 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105343614A (zh) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101637546A (zh) * | 2009-08-20 | 2010-02-03 | 曹书光 | 一种治疗急慢性鼻炎、鼻窦炎的药物 |
CN104147194A (zh) * | 2014-08-26 | 2014-11-19 | 王深涧 | 一种治疗慢性鼻窦炎的中药组合物 |
-
2015
- 2015-11-23 CN CN201510859113.1A patent/CN105343614A/zh active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101637546A (zh) * | 2009-08-20 | 2010-02-03 | 曹书光 | 一种治疗急慢性鼻炎、鼻窦炎的药物 |
CN104147194A (zh) * | 2014-08-26 | 2014-11-19 | 王深涧 | 一种治疗慢性鼻窦炎的中药组合物 |
Non-Patent Citations (2)
Title |
---|
王涛等: "自拟清渊汤合氯嘛合剂治疗慢性鼻窦炎200例", 《安徽中医临床杂志》 * |
肖国士等: "《名医到我家系列丛书 名医推荐家庭必备秘方 珍藏本》", 30 September 2015, 湖南科学技术出版社 * |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103405596B (zh) | 一种治疗鼻窦炎的中药 | |
CN102579774A (zh) | 一种用于治疗颈淋巴结核的中药组合物 | |
CN102614306B (zh) | 治疗慢性鼻窦炎的中药制剂 | |
CN103877429B (zh) | 一种治疗鼻窦炎的中药制剂及制备方法 | |
CN102526459B (zh) | 一种治疗鼻窦炎的中药组合物及其制备方法 | |
CN103393971B (zh) | 一种用于护理鼻炎患者的中药制剂及制备方法 | |
CN103142733B (zh) | 一种治疗上呼吸道感染的中药组合物 | |
CN104225339A (zh) | 一种治疗慢性肺炎的中药制剂及制备方法 | |
CN104147194A (zh) | 一种治疗慢性鼻窦炎的中药组合物 | |
CN103784796A (zh) | 一种治疗单纯性甲状腺肿的中药制剂 | |
CN102657709A (zh) | 一种治疗鼻炎的中药 | |
CN103263614B (zh) | 一种预防或治疗阴道炎的药物组合物 | |
CN105327182A (zh) | 一种治疗儿童百日咳的药物及其制备方法 | |
CN105055934A (zh) | 一种治疗慢性鼻窦炎的药物及制备方法 | |
CN104857414A (zh) | 一种治疗慢性单纯性鼻炎的药物组合物 | |
CN104606533A (zh) | 一种治疗咽炎的中药汤剂 | |
CN105343614A (zh) | 治疗慢性鼻窦炎的中药组合物 | |
CN104606406B (zh) | 一种外用预防变应性鼻炎的中药膏及其制备方法 | |
CN103830486A (zh) | 一种治疗梅核气的中药 | |
CN103417841A (zh) | 一种治疗肺炎的中药制剂 | |
CN103638369B (zh) | 一种治疗乳腺炎的中药制剂 | |
CN105998781A (zh) | 一种治疗急性胃肠炎的药物组合物 | |
CN104840823A (zh) | 一种治疗中耳炎的中药制剂及制法 | |
CN105079346A (zh) | 辛夷鼻炎注射液 | |
CN104524094A (zh) | 一种治疗梅核气的中药 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160224 |
|
RJ01 | Rejection of invention patent application after publication |