CN105311343A - Traditional Chinese medicine preparation for treating acute mastitis - Google Patents
Traditional Chinese medicine preparation for treating acute mastitis Download PDFInfo
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- CN105311343A CN105311343A CN201510793950.9A CN201510793950A CN105311343A CN 105311343 A CN105311343 A CN 105311343A CN 201510793950 A CN201510793950 A CN 201510793950A CN 105311343 A CN105311343 A CN 105311343A
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating acute mastitis. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 6-9 parts of scorpio, 3-9 parts of rhizoma anemarrhenae, 6-12 parts of dandelion, 9-15 parts of honeysuckle flowers, 3-9 parts of manis pentadactyla, 3-9 parts of safflower carthamus, 12-18 parts of safflower carthamus, 10-16 parts of fructus forsythiae, 6-12 parts of frankincense, and 6-12 parts of cassia seeds. The traditional Chinese medicine preparation for treating acute mastitis has the efficacies of clearing away heat and toxic materials, promoting lactation and eliminating swelling, as well as promoting Qi to activate blood, so as to achieve the efficacies of regulating the Qi and blood of the organism, balancing Yin and Yang, dredging the channels of mammary glands, and promoting milk secretion, is convenient to take, good in tolerance, low in cost, free of any toxic or side effect to breast feeding women and infants, and good in safety, and can be widely applied to the clinic treatment for acute mastitis.
Description
Technical field
The present invention relates to the field of Chinese medicines, specifically, relate to a kind of Chinese medicine preparation being used for the treatment of acute mastitis.
Background technology
Acute mastitis is that the acute festering type of mammary gland infects, and often occurs in the 3-4 week in puerperal.Patient mostly is the women of postpartum breastfeeding, is common again with primipara, because it lacks suckling experience; When also can betide wean, because of baby's long teeth after 6 months, skin of nipple is easily caused to damage.Pathogenic bacterium majority is staphylococcus aureus, and minority is streptococcus.Patient feels the enlargement of Ipsilateral mammary gland, pain, can be throbbing pain, and local is red and swollen, and heating is more violent when suckling.Along with the development of inflammation, patient can have shiver with cold, and high heat, arteries and veins is fast, and often have Ipsilateral lymphadenectasis, numeration of leukocyte increases.Acute mastitis is the originally performance in cellulitis sample generally, if local deliquescing in a short time, illustrates that existing abscess is formed.Abscess topical manifestations is relevant with the position depth, the more shallow person in position, and occur that local skin redness is bright in early days, position is darker, and topical manifestations is more not obvious.Abscess can have several, or is successively formed at different time.Abscess can outside ulceration, also can pass latex dust, discharge pus from nipple.Sometimes abscess can be broken in the open texture between mammary gland and pectoralis major, forms retromammary abscess, and infecting severe patient can concurrent septicemia.
Antibiotic is only effective to some patients, and often has the phenomenon of non-rational use of drug and abuse of antibiotics to occur, directly threatens the health of mother and child.Operative treatment wound is comparatively large, and postoperative to affect breast attractive in appearance, and the state of an illness easily repeatedly.Therefore find a kind of successful, toxic and side effects medicine that is little, taking convenience is clinical problem demanding prompt solution.
Primary disease belongs to motherland's medical science " acute mastitis " category.The traditional Chinese medical science thinks that nipple belongs to liver, and breast belongs to stomach, in stomach at the beginning of milk unit, if stagnation of liver-QI gastric heat, depression of liver-QI, the gas of the moon of fainting is not all right and lose in catharsis and add puerperal asthenia, eating and drinking without temperance, causes depression of liver-QI, excessiveness of stomach-heat, row breast can be made not smooth, and qi depression to blood stasis, accumulates in pyretic toxicity and forms carbuncle, therefore treatment focuses on depressed liver-energy dispersing and QI regulating, heat-clearing and toxic substances removing, eliminating stasis and resolving masses, reducing swelling and alleviating pain.
Acute mastitis adopts antibiotic conservative treatment and operative treatment to be main usually.Life-time service antibiotic patient easily produces drug resistance and toxic and side effects is comparatively large, although some patients has certain curative effect, therapeutic effect is not thorough, and easily recurrence after curing, cost is relatively high.Operative treatment wound is large, and postoperative to affect breast attractive in appearance, and the state of an illness easily repeatedly.Chinese medicine has the effect of its uniqueness in treatment acute mastitis, but the clinical Chinese prescription still lacking determined curative effect.
Summary of the invention
The present invention is directed to the deficiencies in the prior art, provide a kind of Chinese medicine preparation for the treatment of acute mastitis, Chinese medicine preparation of the present invention has effect of heat-clearing and toxic substances removing, lactogenesis detumescence, promoting flow of QI and blood, and taking convenience, with low cost, without any side effects, the clinical treatment of acute mastitis can be widely used in.
In order to realize above object, the technical solution adopted in the present invention is as follows:
Treat a Chinese medicine preparation for acute mastitis, be made up of the raw material of following weight portion: Scorpio 6-9 part, Rhizoma Anemarrhenae 3-9 part, Herba Taraxaci 6-12 part, Flos Lonicerae 9-15 part, Squama Manis 3-9 part, Flos Carthami 3-9 part, Radix Bupleuri 12-18 part, Fructus Forsythiae 10-16 part, Olibanum 6-12 part, Semen Cassiae 6-12 part.
Preferably, treat a Chinese medicine preparation for acute mastitis, be made up of the raw material of following weight portion: Scorpio 7 parts, the Rhizoma Anemarrhenae 6 parts, Herba Taraxaci 9 parts, Flos Lonicerae 12 parts, Squama Manis 5 parts, 6 parts, Flos Carthami, Radix Bupleuri 14 parts, Fructus Forsythiae 13 parts, Olibanum 8 parts, Semen Cassiae 8 parts.
Described Chinese medicine preparation is tablet, capsule, buccal tablet, powder or granule.
Preferably, Chinese medicine preparation is capsule.
The Chinese medicine preparation for the treatment of acute mastitis of the present invention is prepared by following steps:
1) mixed by weight by each raw medicinal material, the concentration adding 3-5 times of raw material gross weight is the ethanol of 80-90%, reflux 40-60 minute, filters acquisition first extracting solution;
2) concentration adding 2-3 times of medicinal residues weight in medicinal residues is again the ethanol of 85-90%, and reflux 30-50 minute filters to obtain the second extracting solution;
3) the first extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing ethanol, dry, get dry extract;
4) dry cream is placed in super micron mill pulverizes 1-2 hour, sieve, obtain 200-300 object micropowders;
5) micropowders is added relative to its quality 0.1-0.3 microcrystalline Cellulose doubly, 0.1-0.3 starch doubly, 0.005-0.05 magnesium stearate doubly, mixing, incapsulate in housing, each capsule 0.1g, the Chinese medicine preparation for the treatment of acute mastitis of the present invention can be obtained.
Therapeutic Method: every day 3 times, each 27 days is a course for the treatment of.
The preparation of raw material:
Scorpio: dense vinegar steeps the matter that desalts, and low baking temperature dries;
The Rhizoma Anemarrhenae: removing fibrous root, pick clean impurity, use processed by saline;
Squama Manis: get the Squama Manis sheet picking clean, separately size, separately puts sand in pot and makes popular, add Squama Manis sheet, frying to heaving in time golden yellow, taking out, and sieve shakeout, cools;
Semen Cassiae: low baking temperature is fried when overflowing to fragrance and taken out, Hou Liang.
The pharmacology of each crude drug is as follows:
Scorpio: acrid in the mouth, property is put down, poisonous.Return Liver Channel.Endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.
The Rhizoma Anemarrhenae: bitter in the mouth, sweet, cold in nature.Return lung, stomach, kidney channel.Clearing away heat-fire, promotes the production of body fluid and moisturizes.Clearing away heat-fire, promotes the production of body fluid and moisturizes.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Herba Taraxaci: sweet in the mouth, micro-hardship, cold in nature.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Cure mainly upper respiratory tract infection, eye conjunctivitis, mumps, hyperglycemia, acute mastitis swells and ache, gastritis, dysentery, hepatitis, gallbladder assists inflammation, acute appendicitis, urinary system infection, pelvic inflammatory disease, carbuncle furuncle furuncle, pharyngitis, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, urinary tract infection.
Flos Lonicerae: sweet in the mouth, cold in nature.Return lung, stomach, the heart, large intestine channel.Heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, warm blood fulminant dysentery, anemopyretic cold, epidemic febrile disease is generated heat.
Squama Manis: salty in the mouth, cold nature.Return liver, stomach warp.Blood circulation promoting and dispersing pathogen accumulation, stimulating milk secretion of stimulating the menstrual flow, eliminating carbuncle is burst hard.Main blood stasis amenorrhea, lump in the abdomen, rheumatic arthralgia, agalactia, carbuncle, scrofula.
Flos Carthami: acrid in the mouth, warm in nature.Promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury.
Radix Bupleuri: bitter in the mouth, pungent, cold nature.Return Liver Channel, gallbladder meridian.Depressed liver-energy dispersing and function of gallbladder promoting, thin gas resolving depression, loose effect of fire.Stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus comes off, menoxenia.
Fructus Forsythiae: bitter in the mouth, cool in nature.GUIXIN, liver, gallbladder meridian.Heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.
Olibanum: acrid in the mouth, hardship, warm in nature.GUIXIN, liver, spleen channel.Regulating qi and activating blood, analgesic therapy, chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Semen Cassiae: sweet in the mouth, hardship, salty, cold nature.Return liver, large intestine channel.Clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, constipation.Control wind heat acute conjunctivitis, optic atrohic blindness, nyctalopia, hypertension, hepatitis, cirrhotic ascites, habitual constipation.
Chinese medical theory is thought: acute mastitis and acute mastitis, is expectorant, wet, gas, blood stagnation knot do not fall apart, and changes and is scorching.Because damp and hot poison steams, infringement breast; Or because of stagnation of QI due to depression of the liver, newborn network loses smooth so that breast coagulation of QI-blood, stasis and raw carbuncle; Or because of the nipple that bites when child inhales breast, evil poison invasion causes carbuncle; Or stagnate because of milk, reasons such as breast distension and cause primary disease.The prescription of Chinese medicine preparation of the present invention is with heat-clearing and toxic substances removing, lactogenesis detumescence, promoting flow of QI and blood for principle, and Chinese herbal medicine presses monarch principle prescription, and Scorpio is monarch, heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, blood circulation promoting and blood stasis dispelling, and resolving depression is brought down a fever; The Rhizoma Anemarrhenae, Herba Taraxaci, Flos Lonicerae, Squama Manis are minister, the Rhizoma Anemarrhenae, Herba Taraxaci clearing away heat-fire, hard masses softening and resolving, Flos Lonicerae, Squama Manis activating blood circulation to dissipate blood stasis, dredge the meridian passage, reducing swelling and alleviating pain, and principal drug assistance strengthens effect of its hard masses softening and resolving, dispersing the stagnated live-QI to relieve the stagnation of QI altogether; Flos Carthami, Radix Bupleuri, Fructus Forsythiae, Olibanum, Semen Cassiae are adjuvant, can strengthen the effect of the monarch and his subjects, can play again the effect of eliminating stasis to stop pain, diuretic relieving constipation.
Beneficial effect of the present invention: the Chinese medicine preparation for the treatment of acute mastitis of the present invention select the Chinese medicine such as medicine Scorpio, Herba Taraxaci, Flos Lonicerae of integration of edible and medicinal herbs and other plurality of Chinese composition is composite forms, there is effect of heat-clearing and toxic substances removing, lactogenesis detumescence, promoting flow of QI and blood, to reach reconditioner bromhidrosis blood, Yin Yang balancing, dredging galactophore meridian, promote effect of milk excretion, and taking convenience, better tolerance, with low cost, to women breast-feeding their children and infant without any side effects, safety is good, can be widely used in the clinical treatment of acute mastitis.
Detailed description of the invention
Below by way of the description of detailed description of the invention, the invention will be further described, but this is not limitation of the present invention, those skilled in the art are according to basic thought of the present invention, various amendment or improvement can be made, but only otherwise depart from basic thought of the present invention, all within the scope of the present invention.
Present invention also offers the preparation of raw material:
Scorpio: dense vinegar steeps the matter that desalts, and low baking temperature dries;
The Rhizoma Anemarrhenae: removing fibrous root, pick clean impurity, use processed by saline;
Squama Manis: get the Squama Manis sheet picking clean, separately size, separately puts sand in pot and makes popular, add Squama Manis sheet, frying to heaving in time golden yellow, taking out, and sieve shakeout, cools;
Semen Cassiae: low baking temperature is fried when overflowing to fragrance and taken out, Hou Liang.
embodiment 1
Treat a Chinese medicine preparation for acute mastitis, be made up of the raw material of following weight portion: Scorpio 9 parts, the Rhizoma Anemarrhenae 3 parts, Herba Taraxaci 6 parts, Flos Lonicerae 15 parts, Squama Manis 9 parts, 3 parts, Flos Carthami, Radix Bupleuri 18 parts, Fructus Forsythiae 10 parts, Olibanum 6 parts, Semen Cassiae 12 parts.
Described Chinese medicine preparation is capsule.
The Chinese medicine preparation for the treatment of acute mastitis of the present invention is prepared by following steps:
1) mixed by weight by each raw medicinal material, the concentration adding 3 times of raw material gross weights is the ethanol of 90%, reflux 40 minutes, filters acquisition first extracting solution;
2) concentration adding 2 times of medicinal residues weight in medicinal residues is again the ethanol of 85%, and reflux 50 minutes filters to obtain the second extracting solution;
3) the first extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing ethanol, dry, get dry extract;
4) dry cream is placed in super micron mill and pulverizes 1 hour, sieve, obtain 300 object micropowders;
5) added by micropowders relative to the microcrystalline Cellulose of its quality 0.1 times, the starch of 0.3 times, the magnesium stearate of 0.005 times, mixing, incapsulates in housing, each capsule 0.1g, can obtain the Chinese medicine preparation for the treatment of acute mastitis of the present invention.
embodiment 2
Treat a Chinese medicine preparation for acute mastitis, be made up of the raw material of following weight portion: Scorpio 7 parts, the Rhizoma Anemarrhenae 6 parts, Herba Taraxaci 9 parts, Flos Lonicerae 12 parts, Squama Manis 5 parts, 6 parts, Flos Carthami, Radix Bupleuri 14 parts, Fructus Forsythiae 13 parts, Olibanum 8 parts, Semen Cassiae 8 parts.
Described Chinese medicine preparation is capsule.
The Chinese medicine preparation for the treatment of acute mastitis of the present invention is prepared by following steps:
1) mixed by weight by each raw medicinal material, the concentration adding 4 times of raw material gross weights is the ethanol of 85%, reflux 50 minutes, filters acquisition first extracting solution;
2) concentration adding 2.5 times of medicinal residues weight in medicinal residues is again the ethanol of 87%, and reflux 40 minutes filters to obtain the second extracting solution;
3) the first extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing ethanol, dry, get dry extract;
4) dry cream is placed in super micron mill and pulverizes 1.5 hours, sieve, obtain 250 object micropowders;
5) added by micropowders relative to the microcrystalline Cellulose of its quality 0.2 times, the starch of 0.2 times, the magnesium stearate of 0.02 times, mixing, incapsulates in housing, each capsule 0.1g, can obtain the Chinese medicine preparation for the treatment of acute mastitis of the present invention.
embodiment 3
Treat a Chinese medicine preparation for acute mastitis, be made up of the raw material of following weight portion: Scorpio 6 parts, the Rhizoma Anemarrhenae 9 parts, Herba Taraxaci 12 parts, Flos Lonicerae 9 parts, Squama Manis 3 parts, 9 parts, Flos Carthami, Radix Bupleuri 12 parts, Fructus Forsythiae 16 parts, Olibanum 12 parts, Semen Cassiae 6 parts.
Described Chinese medicine preparation is capsule.
The Chinese medicine preparation for the treatment of acute mastitis of the present invention is prepared by following steps:
1) mixed by weight by each raw medicinal material, the concentration adding 5 times of raw material gross weights is the ethanol of 80%, reflux 60 minutes, filters acquisition first extracting solution;
2) concentration adding 3 times of medicinal residues weight in medicinal residues is again the ethanol of 90%, and reflux 30 minutes filters to obtain the second extracting solution;
3) the first extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing ethanol, dry, get dry extract;
4) dry cream is placed in super micron mill and pulverizes 2 hours, sieve, obtain 200 object micropowders;
5) added by micropowders relative to the microcrystalline Cellulose of its quality 0.3 times, the starch of 0.1 times, the magnesium stearate of 0.05 times, mixing, incapsulates in housing, each capsule 0.1g, can obtain the Chinese medicine preparation for the treatment of acute mastitis of the present invention.
application of clinic experimentation
Subject Population: choose the acute mastitis patient that 97 examples are in age of sucking, product reckling in age 21 years old, the maximum 37 years old; All within 1-5 days, go to a doctor in morbidity.Wherein primipara 81 example, multipara 16 example.One-sided patient 81 example, bilateral sends out patient 16 example.
Diagnostic criteria:
1. patient is women breast-feeding their children, is especially common with primipara, and premorbid has the damaged history of cracked nipple and the smooth history of human milk silt more.
2. local symptom: breast red and swollen heat pain suppurates.Ipsilateral axillary gland can have enlargement.
3. General Symptoms: to shiver, high hot, irritated, weak, dry stool etc.
4. laboratory examination: numeration of leukocyte raises, and particularly neutrophilic granulocyte number obviously increases.During suppuration, local suction can have purulent secretion.
Therapeutic Method: take capsule of the present invention every day 3 times, each 27 days is a course for the treatment of.
Criterion of therapeutical effect:
1. cure: inflammation and General Symptoms disappear;
2. effective: inflammation and General Symptoms partial disappearance, scleroma is left in local;
3. invalid: treatment front and back are without significant change or reverse serious.
Therapeutic outcome: 97 routine acute mastitis patients are through the treatment of 1-2 the course for the treatment of, and clinical cure 90 example, effective 5 examples, invalid 2 is routine, total effective rate 97.9%.
The Chinese medicine preparation taking convenience for the treatment of acute mastitis of the present invention, evident in efficacy, with low cost, and without any side effects, there is good potential applicability in clinical practice.
Those skilled in the art, according to basic thought of the present invention, can make various amendment or improvement, but only otherwise depart from basic thought of the present invention, all within the scope of the present invention.
Claims (4)
1. treat the Chinese medicine preparation of acute mastitis for one kind, it is characterized in that, be made up of the raw material of following weight portion: Scorpio 6-9 part, Rhizoma Anemarrhenae 3-9 part, Herba Taraxaci 6-12 part, Flos Lonicerae 9-15 part, Squama Manis 3-9 part, Flos Carthami 3-9 part, Radix Bupleuri 12-18 part, Fructus Forsythiae 10-16 part, Olibanum 6-12 part, Semen Cassiae 6-12 part.
2. Chinese medicine preparation according to claim 1, it is characterized in that, be made up of the raw material of following weight portion: Scorpio 7 parts, the Rhizoma Anemarrhenae 6 parts, Herba Taraxaci 9 parts, Flos Lonicerae 12 parts, Squama Manis 5 parts, 6 parts, Flos Carthami, Radix Bupleuri 14 parts, Fructus Forsythiae 13 parts, Olibanum 8 parts, Semen Cassiae 8 parts.
3. Chinese medicine preparation according to claim 1 and 2, is characterized in that, described Chinese medicine preparation is tablet, capsule, buccal tablet, powder or granule.
4. Chinese medicine preparation according to claim 3, is characterized in that, described Chinese medicine preparation is capsule.
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| CN201510793950.9A CN105311343A (en) | 2015-11-18 | 2015-11-18 | Traditional Chinese medicine preparation for treating acute mastitis |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1915290A (en) * | 2006-08-25 | 2007-02-21 | 黄志良 | Medication of medical broth for treating acute mastitis, and preparation method |
| CN102038911A (en) * | 2009-10-22 | 2011-05-04 | 景松森 | Traditional Chinese medicine preparation for treating acute mastitis |
| CN102100872A (en) * | 2010-11-29 | 2011-06-22 | 刘耐芬 | Chinese medicine preparation for treating mastitis |
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- 2015-11-18 CN CN201510793950.9A patent/CN105311343A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1915290A (en) * | 2006-08-25 | 2007-02-21 | 黄志良 | Medication of medical broth for treating acute mastitis, and preparation method |
| CN102038911A (en) * | 2009-10-22 | 2011-05-04 | 景松森 | Traditional Chinese medicine preparation for treating acute mastitis |
| CN102100872A (en) * | 2010-11-29 | 2011-06-22 | 刘耐芬 | Chinese medicine preparation for treating mastitis |
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