CN105311341A - Traditional Chinese medicine preparation for oral administration in synchronous treatment and prevention of 'four highs' - Google Patents
Traditional Chinese medicine preparation for oral administration in synchronous treatment and prevention of 'four highs' Download PDFInfo
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- CN105311341A CN105311341A CN201410368557.0A CN201410368557A CN105311341A CN 105311341 A CN105311341 A CN 105311341A CN 201410368557 A CN201410368557 A CN 201410368557A CN 105311341 A CN105311341 A CN 105311341A
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Abstract
The invention relates to a traditional Chinese medicine preparation for oral administration in synchronous treatment and prevention of 'four highs', in particular to a traditional Chinese medicine preparation for oral administration in the synchronous treatment and prevention of 'four highs', high blood glucose, high blood pressure, high blood lipid and high blood viscosity. The preparation comprises following materials: Radix Salviae Miltiorrhizae 150-200 parts, Radix Astragali 130-180 parts, Radix Notoginseng and Rhizoma Anemarrhenae (125-170 parts each), Fructus Lycii, Folium Ginkgo and Radix Puerariae (120-165 parts each), Radix Scrophulariae, Folium Mori, Semen Persicae, Herba Epimedii, Flos Chrysanthemi and Radix Paeoniae Alba (115-160 parts each), and Radix Glycyrrhizae 30-50 parts. The preparation features significant curative effect, process simplicity and convenience and low manufacturing cost, can treat and prevent 'four highs', high blood glucose, high blood pressure, high blood lipid and high blood viscosity synchronously and effectively, and can significantly improve the immunity of people with 'four highs' and effectively protect their lives.
Description
Technical field
What patent of the present invention related to is a kind of medicine, and what be specifically related to is a kind of synchronous therapeutic and prevention " 4 is high " the i.e. innerwear Chinese medicine preparation of hyperglycemia, hypertension, hyperlipidemia, high blood viscosity.Said preparation feature is: effectively and synchronous therapeutic and prevention " 4 is high ", and can improve the immunity of " 4 height " patient, the life of available protecting " 4 height " patient.
Background technology
Along with the raising of living standards of the people, " 4 high " i.e. hyperglycemia, hypertension, hyperlipidemia, high blood viscosity person is also ascendant trend year by year." 4 is high " can cause multiple complications, and namely such as cardio cerebrovascular affection, diabetes etc. are one of major complications.Interrelated data shows, because " 4 is high " reason directly causes the patient numbers of diabetes, cardio cerebrovascular affection to account for the ratio of diabetes, cardio cerebrovascular affection patient nearly 90%.World Health Organization's interrelated data shows, the whole world is used for the treatment of every year " 4 high " and the medical expense of various complication that causes because of " 4 is high " factor, in recent years often every year more than 1 trillion dollars.
At present, " 4 the is high " patient of the existing ill diagnosis and treatment record on the regular payroll in the whole world has exceeded nearly 1,000,000,000 (having patient to reach 12-15 hundred million in fact).Latest survey shows, and China now exceedes India, becomes the whole world " 4 is high " the first big country.The patient that China is now diagnosed as " 4 is high ", up to 2.9 hundred million, has crowd more than 400,000,000 people in fact.In other words, China on average just has in every 3-3.5 people a people to be " 4 is high " people now, or possesses the sign in early stage of " 4 is high ".Thus, " 4 is high " patients that China is potential is huge.
In the last few years, China's " 4 is high " sickness rate increases year by year, trace it to its cause, main and the aging of population, move unbalance, nutrition deviation as often drunk cola, to have fast food etc. higher fatty acid, high heat food is relevant, relevant with the factor such as abnormal obesity, also with can not to have regular physical checkups and edible in time medicine, health food, normal food and the daily life of " 4 is high " can treated and prevent is accustomed to relevant.These reasons just, cause " 4 high " complication rate and case fatality rate very high.International interrelated data display: more than 10 times of " 4 is high " reason case fatality rate right and wrong " 4 is high " personnel.In a word, the too high sickness rate that " 4 is high " directly and indirectly causes and case fatality rate, human health in serious threat at present.Therefore, treat " 4 is high " and prevent in time, extremely urgent pendulum is in face of people.
At present, for the research and apply of " 4 is high ", cause the extensive concern of scholar in the industry, research worker and social relevant person, obtained many achievements in research, namely patent of the present invention is a kind of synchronous effectively treatment and prevention " 4 is high " and has the innerwear Chinese medicine preparation of " treating both the principal and secondary aspects of a disease " effect.
Summary of the invention
The present invention is to provide the innerwear Chinese medicine preparation of a kind of synchronous therapeutic and prevention " 4 is high ".
Patent of the present invention is achieved by the following technical programs: above-mentioned group's thing is added 8 times amount soak by water 2 times, each 1h; Filter, collecting decoction, being evaporated to relative density is 1.10-1.14(50 DEG C) clear paste; Adding ethanol makes alcohol content reach 70%, places 24 hours, filters; Supernatant decompression recycling ethanol, being concentrated into relative density is 1.25-1.30(50 DEG C-70 DEG C) thick paste; Vacuum drying (less than 70 DEG C); Dried cream powder is broken into fine powder, to obtain final product.
Patent of the present invention has evident in efficacy, simple process, cheap feature, effectively can treat and prevent " 4 is high " patient, and can significantly improve the immunity of " 4 is high " patient, its life of available protecting.
Detailed description of the invention
Detailed description of the invention one:
Patented technology of the present invention, is made up of following article:
Radix Salviae Miltiorrhizae 150-200 parts, the Radix Astragali 130-180 parts, Radix Notoginseng, the Rhizoma Anemarrhenae (each 125-170 parts), Fructus Lycii, Folium Ginkgo, Radix Puerariae (each 120-165 parts), Radix Scrophulariae, Folium Mori, Semen Persicae, Herba Epimedii, Flos Chrysanthemi, the Radix Paeoniae Alba (each 115-160 parts), 30-50 parts, Radix Glycyrrhizae.
Detailed description of the invention two:
The concrete manufacture method of patented technology functional food of the present invention is: above-mentioned group's thing is added 8 times amount soak by water 2 times, each 1h; Filter, collecting decoction, being evaporated to relative density is 1.10-1.14(50 DEG C) clear paste; Adding ethanol makes alcohol content reach 70%, places 24 hours, filters; Supernatant decompression recycling ethanol, being concentrated into relative density is 1.25-1.30(50 DEG C-70 DEG C) thick paste; Vacuum drying (less than 70 DEG C); Dried cream powder is broken into fine powder, to obtain final product.
Detailed description of the invention two:
By practice of pharmacy, invention formulation can be prepared into various clinical pharmaceutical dosage form, comprise oral liquid, capsule, tablet, drop pill, granule, suspensoid, any one in skin drug-delivery preparation, injection, suppository, aerosol etc.
Detailed description of the invention three:
Patent of the present invention is achieved by following preclinical study.
One, patent of the present invention is through the display of pharmacodynamic experiment result of study, has following functions:
1. there are the effect of cardio cerebrovascular affection of stronger improvement experimental " 4 is high " rat, the effect of the blood viscosity that reduces blood pressure, improves.
2. have " 4 is high " pathological changes rat and fall hypoglycemic effect in various degree, especially more obvious with heavy dose group.
3. can significantly improve the humoral immune function of " 4 is high " immunologic hypofunction mice.
4. obviously can improve " 4 is high " diseased mice ear microcirculation.
5. " 4 is high " pathological changes Peripheral Nerves in Rats and blood capillary damage all there are is stronger protective effect and improved in various degree.
Two, patent of the present invention is studied through toxicological experiment, shows following result:
1, acute toxicity testing: mouse stomach maximum dosage-feeding is equivalent to 186 times of quantity, observes 14 days, and this medicine increases buck body weight certain influence, and have no significant effect jenny body weight, Novel presentation does not appear in animal, without dead.
2, long term toxicity test
To rat administration 24 weeks, low, in, the every Testing index of heavy dose of group no significant difference more equal to matched group; Convalescent period (drug withdrawal 4 weeks), its each dosage group indices compares no significant difference with matched group.The each internal organs of pathological examination are showed no the obvious toxic pathological change that this guiding drug rises.
Three, proprietary preparation of the present invention have passed the whole pharmacy researchs comprising preparation process research, quality standard research, stability study.
Claims (3)
1. a synchronous therapeutic and prevention " 4 is high " the i.e. innerwear Chinese medicine preparation of hyperglycemia, hypertension, hyperlipidemia, high blood viscosity, it is characterized in that it is made up of following article: Radix Salviae Miltiorrhizae 150-200 parts, the Radix Astragali 130-180 parts, Radix Notoginseng, the Rhizoma Anemarrhenae (each 125-170 parts), Fructus Lycii, Folium Ginkgo, Radix Puerariae (each 120-165 parts), Radix Scrophulariae, Folium Mori, Semen Persicae, Herba Epimedii, Flos Chrysanthemi, the Radix Paeoniae Alba (each 115-160 parts), 30-50 parts, Radix Glycyrrhizae.
2. an innerwear Chinese medicine preparation for synchronous therapeutic and prevention " 4 is high ", is characterized in that concrete manufacture method is: above-mentioned article are added 8 times amount soak by water 2 times, each 1h; Filter, collecting decoction, being evaporated to relative density is 1.10-1.14(50 DEG C) clear paste; Adding ethanol makes alcohol content reach 70%, places 24 hours, filters; Supernatant decompression recycling ethanol, being concentrated into relative density is 1.25-1.30(50 DEG C-70 DEG C) thick paste; Vacuum drying (less than 70 DEG C); Dried cream powder is broken into fine powder, to obtain final product.
3. press practice of pharmacy, proprietary preparation of the present invention can be prepared into various clinical pharmaceutical dosage form according to related standards, comprise the dosage form of oral formulations or parenterai administration, mainly refer to: capsule, tablet, drop pill, granule, suspensoid, oral liquid, any one in percutaneous drug delivery agent, injection, suppository, aerosol etc.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410368557.0A CN105311341A (en) | 2014-07-30 | 2014-07-30 | Traditional Chinese medicine preparation for oral administration in synchronous treatment and prevention of 'four highs' |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410368557.0A CN105311341A (en) | 2014-07-30 | 2014-07-30 | Traditional Chinese medicine preparation for oral administration in synchronous treatment and prevention of 'four highs' |
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| CN105311341A true CN105311341A (en) | 2016-02-10 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410368557.0A Pending CN105311341A (en) | 2014-07-30 | 2014-07-30 | Traditional Chinese medicine preparation for oral administration in synchronous treatment and prevention of 'four highs' |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110025734A (en) * | 2019-04-17 | 2019-07-19 | 于骏梁 | A kind of reduction hypertension, hyperlipidemia and Tea containing traditional Chinese medicine of hyperglycemia and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101011539A (en) * | 2006-09-27 | 2007-08-08 | 董新华 | Traditional Chinese medicine for preventing, treating and reverting diabetes and its complications |
| CN101032592A (en) * | 2007-04-09 | 2007-09-12 | 唐贝宁医药科技（北京）有限公司 | Novel formula of pure Chinese traditional medicine agent and the preparing method |
| CN101401601A (en) * | 2006-10-18 | 2009-04-08 | 吴建生 | Five-leaf tea for reducing blood pressure, blood fat and blood sugar |
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2014
- 2014-07-30 CN CN201410368557.0A patent/CN105311341A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101011539A (en) * | 2006-09-27 | 2007-08-08 | 董新华 | Traditional Chinese medicine for preventing, treating and reverting diabetes and its complications |
| CN101401601A (en) * | 2006-10-18 | 2009-04-08 | 吴建生 | Five-leaf tea for reducing blood pressure, blood fat and blood sugar |
| CN101032592A (en) * | 2007-04-09 | 2007-09-12 | 唐贝宁医药科技（北京）有限公司 | Novel formula of pure Chinese traditional medicine agent and the preparing method |
Non-Patent Citations (1)
| Title |
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| 杨如哲，等: "《健康与合理营养》", 30 April 2004, 上海科学技术文献出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110025734A (en) * | 2019-04-17 | 2019-07-19 | 于骏梁 | A kind of reduction hypertension, hyperlipidemia and Tea containing traditional Chinese medicine of hyperglycemia and preparation method thereof |
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Application publication date: 20160210 |