CN105168762A

CN105168762A - Medicament for treating stomach distension and preparation method thereof

Info

Publication number: CN105168762A
Application number: CN201510514232.3A
Authority: CN
Inventors: 霍传生
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-08-21
Filing date: 2015-08-21
Publication date: 2015-12-23

Abstract

The invention discloses a medicament for treating stomach distension. The medicament is prepared from the following components in parts by weight: 9 to 13 parts of evodia, 10 to 15 parts of lotus plumule, 8 to 12 parts of osmanthus fragrans, 9 to 15 parts of notholirion hyacinthinum, 7 to 12 parts of minced orchid root, 11 to 16 parts of ginseng, 5 to 10 parts of loquat core, 9 to 14 parts of phymatopsis griffithiana, 8 to 14 parts of arenaria serpyllifolia, 10 to 16 parts of clove, 6 to 12 parts of gyrophora hypocrocina, 10 to 13 parts of beet root, 6 to 12 parts of root of longflower stringbush, 8 to 15 parts of betel nut, 7 to 13 parts of jasminum grandiflorum, and 10 to 14 parts of lotus petiole. The medicament has the functions of eliminating dampness, inducing diuresis, purging fire, and removing toxicity, at the same time enhances the functions of invigorating spleen, boosting qi, tonifying spleen, and nourishing stomach, can treat symptoms of stomach duct pain, nausea, vomiting, bad appetite, and the like, and does not have any side effect.

Description

A kind of medicament and preparation method for the treatment of flatulence

Technical field

The present invention relates to traditional Chinese medicine field, particularly relate to a kind of medicament for the treatment of flatulence and preparation method thereof.

Background technology

Flatulence is a kind of very common clinical symptoms, and the traditional Chinese medical science is referred to as " gastral cavity painful abdominal mass ".The reason of flatulence is caused to have many-sided, as stress, dyspepsia etc., mainly gastric dynamic dysfunction.The clinical manifestation of flatulence is: be generally glutted after meal, belch, and uneasy in either sitting or lying, has lost all desire for food and drink; The repeatability of flatulence and chronicity can cause gastritis, digestive tract ulcer, even can develop into gastric cancer.

Flatulence disease head sees " Ling Shu Miraculous Pivot or Divine Axis is swollen opinion ", clinically often to see with pain so that gastral cavilty painful abdominal mass is swollen, and often based on distension, be common in the relevant diseases such as the chronic superfi cial gastritis of modern medicine, chronic atrophic gastritis, gastrointestinal motility disorder and Helicobacter pylori infection.Flatulence occur in stomach internal organs, stomach internal organs be by stomach-Yin, stomach Tianjin, stomach sun, gastric qi formed, wherein with cloudy Tianjin for body, with yang-energy for, collaborate completes being received to things, becomes thoroughly decomposed and moves down the function of small intestinal.The basic pathogenesis of primary disease is middle burnt disorder of QI movement, abnormal ascending-descending of QI, and the cause of disease is how unsuccessful by feelings will, and eating and drinking without temperance or evil criminal's taste, cause taste movement of QI being out of order, and diseased region is at stomach, and design liver spleen two is dirty.The spleen has the function to transport and transform nutrients, main the lucid yang sending up, stomach receiving food and drink, and main leading to falls, and the transportation capabilities of taste have in the catharsis of liver, therefore pathogenesis key is the liver failing to maintain the normal flow of QI, dysfunction of the spleen in transportation, stomach-QI being unable to descend normally.

Application publication number CN102552855A(application number 201210033039.4) Chinese invention patent document disclose a kind of medicine for the treatment of flatulence and preparation method thereof, be made up of the crude drug in following weight range: Pseudobulbus Bletillae (Rhizoma Bletillae) 10-15 gram, Radix Codonopsis 10-12 gram, Semen Raphani 12-15 gram, Pericarpium Citri Reticulatae 8-12 gram, Cortex Magnoliae Officinalis 8-12 gram, Endothelium Corneum Gigeriae Galli 8-12 gram, Radix Salviae Miltiorrhizae 12-18 gram, Rhizoma Chuanxiong 8-12 gram, Rhizoma Polygonati Odorati 10-12 gram, Massa Medicata Fermentata 8-10 gram, Fructus Jujubae 10-15 gram, Rhizoma Pinelliae 10-12 gram, Fructus Amomi 6-8 gram, Radix Glycyrrhizae 6-8 gram, Fructus Hordei Germinatus 8-10 gram, Rhizoma Dioscoreae 8-12 gram, Radix Et Rhizoma Rhei 8-12 gram, Herba Asari 10-15 gram, Fructus Amomi Rotundus 10-12 gram, Fructus Crataegi 4-8 gram, Radix Ophiopogonis 6-10 gram, Radix Aucklandiae 10-12 gram, Rhizoma Zingiberis 10-14 gram, Fructus Aurantii 10-12 gram, Fructus Perillae 10-14 gram, Semen Persicae 12-16 gram, Radix Angelicae Sinensis 15-25 gram, Haematitum 4-6 gram, Magnetitum 4-8 gram, Poria 10-14 gram, Herba Menthae 3-6 gram.Application publication number CN104399040A(application number 201410703288.9) Chinese invention patent document disclose a kind of medicine for the treatment of flatulence and preparation method thereof, be prepared from by the crude drug of following parts by weight proportioning: Rhizoma Atractylodis Macrocephalae 3-15g, Rhizoma Pinelliae 3-8g, Endothelium Corneum Gigeriae Galli 3-9g, Rhizoma Dioscoreae 7-13g, Rhizoma Zingiberis 2-5g, Haematitum 9-15g, Radix Paeoniae Alba 3-9g, Cortex Magnoliae Officinalis 3-9g, Rhizoma Zingiberis Recens 3-9g.Application publication number CN104173906A(application number 201410476041.8) Chinese invention patent document disclose a kind of Chinese medicine composition for the treatment of flatulence, be made up of the raw material of following weight portion: Rhizoma Corydalis 20-35 part, Rhizoma Cyperi 18-25 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 20-30 part, Flos Caryophylli 15-25 part, Fructus Citri Sarcodactylis 10-20 part, Semen Raphani 5-10 part, Pericarpium Citri Reticulatae 5-15 part, Fructus Amomi Rotundus 5-10 part, Fructus psidii guajavae immaturus 5-10 part, Fructus Setariae Germinatus (parched) 5-10 part.

The common medicine of current treatment flatulence is mainly in order to strengthen gastric motility, but long-term taking can cause the dependency of human body, and simultaneously medicine is chemosynthesis, there is side effect more or less to human body.Chinese traditional treatment primary disease, treating both the principal and secondary aspects of a disease, for different pathogenesis Coryza Treated by Syndrome Differentiation, evident in efficacy.

Summary of the invention

For the deficiencies in the prior art, the object of this invention is to provide that a kind of easy to prepare, compatibility is simple, the medicament of the treatment flatulence of determined curative effect and preparation method thereof.This medicament is applied widely and have no side effect.

Technical scheme of the present invention is:

Treat a medicament for flatulence, be prepared from by following bulk drugs, be weight portion: Fructus Evodiae 9-13; Plumula Nelumbinis 10-15; Liquor Flos osmanthi Distillata 8-12; Bullus Notholirionis Bulbuliferi 9-15; Broken orchid root 7-12; Radix Ginseng 11-16; Radix Eriobotryae 5-10; Phymatopsis griffithiana (Hook.) J. Sm. 9-14; Herba Arenariae Serpyllifoliae 8-14; Flos Caryophylli 10-16; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 6-12; Radix Betae 10-13; Radix Wikstroemiae Dolichanthae 6-12; Semen Arecae 8-15; Flos jasmini 7-13; Petiolus nelumbinis 10-14.

In preferred scheme, Fructus Evodiae 10-12; Plumula Nelumbinis 11-14; Liquor Flos osmanthi Distillata 9-11; Bullus Notholirionis Bulbuliferi 11-13; Broken orchid root 8.5-10.5; Radix Ginseng 12.5-14.5; Radix Eriobotryae 6.5-8.5; Phymatopsis griffithiana (Hook.) J. Sm. 10-13; Herba Arenariae Serpyllifoliae 10-12; Flos Caryophylli 12-14; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 8-10; Radix Betae 11-12; Radix Wikstroemiae Dolichanthae 8-10; Semen Arecae 10-13; Flos jasmini 8.5-11.5; Petiolus nelumbinis 11-13.

Be more preferably, Fructus Evodiae 11; Plumula Nelumbinis 12.5; Liquor Flos osmanthi Distillata 10; Bullus Notholirionis Bulbuliferi 12; Broken orchid root 9.5; Radix Ginseng 13.5; Radix Eriobotryae 7.5; Phymatopsis griffithiana (Hook.) J. Sm. 11.5; Herba Arenariae Serpyllifoliae 11; Flos Caryophylli 13; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 9; Radix Betae 11.5; Radix Wikstroemiae Dolichanthae 9; Semen Arecae 11.5; Flos jasmini 10; Petiolus nelumbinis 12.

Treat a medicament for flatulence, be made into pharmaceutically acceptable pill, preparation method is as follows:

(1) Radix Ginseng is put in medicine pot and is added cold water and do not have powder 1-3cm to soak, then slow fire boiling 20-30 minute (preferred slow fire boiling 25 minutes), and filter, filtrate is for subsequent use;

(2) Fructus Evodiae, Radix Eriobotryae and Semen Arecae are mixed, the yellow wine adding 10%-14% is mixed thoroughly (yellow wine preferably adding 12% is mixed thoroughly), adds a cover vexed 6-10 minute (preferably adding a cover vexed 8 minutes), takes out, and slow fire heating fried dry is degree, smashs into fine powder to pieces, for subsequent use; Plumula Nelumbinis is cleaned, and is together placed in hot pot with Flos Caryophylli, and slow fire heats, and dries, and smashs to pieces and porphyrize powder, for subsequent use;

(3) Bullus Notholirionis Bulbuliferi, broken orchid root, Phymatopsis griffithiana (Hook.) J. Sm., Herba Arenariae Serpyllifoliae, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Radix Betae, Radix Wikstroemiae Dolichanthae, Flos jasmini and Petiolus nelumbinis are placed in marmite, add the clear water (preferably adding the clear water of 8 times of raw material doses) of 7-9 times of raw material dose, slow fire heating decoction twice, first time decocts 20-40 minute (preferably first time decocts 30 minutes), second time decocts 16-28 minute (preferably second time decocts 22 minutes), merge twice decocting liquid, filter, filtrate reduced in volume to 80 DEG C relative density is the thick paste of 1.25-1.28, for subsequent use;

(4) joined in above-mentioned thick paste by the raw material medicated powder after step (1), (2) process, slowly add Liquor Flos osmanthi Distillata while stirring, mixing, is processed into the pill of Semen Firmianae size, obtains final product.

Above-mentioned a kind of preparation method for the treatment of the pill of flatulence, preferred scheme is, the time of soaking in step (1) is 1-2 hour (the preferred time of soaking is 1.3-1.7 hour, and the time of the immersion be more preferably is 1.5 hours).

The preparation method of described capsule is:

(1) Fructus Evodiae, broken orchid root, Radix Eriobotryae, Flos Caryophylli, Radix Wikstroemiae Dolichanthae and Semen Arecae are placed in traditional Chinese medicine drying machine, in 45-55 DEG C of dry 2-3 hour (being preferable over 50 DEG C of dryings 2.5 hours), taking out, are together ground into fine powder, are placed in penetrating bag, for subsequent use;

(2) the penetrating bag of step (1) gained is placed in hermetic container, add dehydrated alcohol lixiviate, jolting every day period 3-5 time (preferred jolting every day 4 times), collect lixiviating solution, three layers of cotton cloth filter, filtrate recycling ethanol, being evaporated to 65 DEG C of relative densities is the clear paste of 1.07-1.10, for subsequent use;

(3) by Radix Ginseng shave, fully dry, pulverize into fine powder with Plumula Nelumbinis, Bullus Notholirionis Bulbuliferi, Phymatopsis griffithiana (Hook.) J. Sm., Herba Arenariae Serpyllifoliae, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Radix Betae, Flos jasmini with Petiolus nelumbinis, for subsequent use;

(4) step (3) gained raw material medicated powder is joined in step (2) gained clear paste, add Liquor Flos osmanthi Distillata simultaneously, add while stirring mass fraction be 8.5% dextrin fine powder and mass fraction be the microcrystalline Cellulose of 6.5%, mixing, granulates, granulate, dry, cross No. four sieves, incapsulate shell, to obtain final product.

Above-mentioned a kind of preparation method for the treatment of the capsule of flatulence, preferred scheme is, in step (2), the time of lixiviate is 2-6 days (time of preferred lixiviate is 3-5 days, and the time of the lixiviate be more preferably is 4 days).

The preparation method of described tablet is:

(1) Radix Ginseng shave, dries, and is ground into fine powder, for subsequent use; Plumula Nelumbinis and the mixing of Semen Arecae sheet, the liquorice beverage adding 30%-50% is mixed thoroughly (liquorice beverage preferably adding 40% is mixed thoroughly), in steamer, steams supreme gas for degree, takes out, dry, smash into fine powder to pieces, for subsequent use;

(2) crude drug except Radix Ginseng, Plumula Nelumbinis, Semen Arecae sheet and Liquor Flos osmanthi Distillata is placed in Chinese medicament extracting device, with second alcohol and water for solvent (volume ratio of second alcohol and water is for 1:2), the amount of solvent is 4-7 times (amount of preferred solvent is 5.5 times of raw material dose) of raw material dose, heating and refluxing extraction 35-55 minute (preferred heating and refluxing extraction 45 minutes), filter, filtrate recycling ethanol, being evaporated to 80 DEG C of relative densities is the thick paste of 1.20-1.23,74-82 DEG C of vacuum drying (preferably 78 DEG C of vacuum dryings), get dry extract powder, cool, porphyrize, for subsequent use;

(3) the raw material medicated powder after step (1) being processed and Liquor Flos osmanthi Distillata join in above-mentioned dried cream powder, add other adjuvant while stirring, and mixing is dry, is pressed into tablet, obtains final product.

Above-mentioned a kind of preparation method for the treatment of the tablet of flatulence, preferred scheme is, adjuvant described in step (3) is the amylum pregelatinisatum of 11% raw material dose and the magnesium stearate of 6% raw material dose.

The preparation method of described water preparation is:

(1) getting Semen Arecae sheet puts in parch container, and slow fire heats, and stir-fries to coke yellow, for subsequent use; Fructus Evodiae and Radix Eriobotryae are placed in hermetic container, the yellow wine adding 0.15-0.25 times amount stirs (yellow wine preferably adding 0.2 times amount stirs), vexed 10 minutes, take out, put in parch container, little fire heating fried dry is degree, taking-up cools, together be placed in mortar with Semen Arecae sheet, be ground into fine powder, for subsequent use;

(2) Radix Ginseng and Plumula Nelumbinis are together put and are added cold water in medicine pot and do not have powder, slow fire boiling 40-60 minute (preferred slow fire boiling 50 minutes), and filter, filtrate is for subsequent use; It is swollen that Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) increases blister, extract moisture, put in hot pot, the Oleum Brassicae campestris adding 15%-25% times amount stir-fries 3-6 minute (Oleum Brassicae campestris preferably adding 20% times amount stir-fries 4.5 minutes), add the boiled water slow fire boiling 12-20 minute boiled water slow fire boiling of 2 times amount (preferably add 16 minutes) of 1-3 times amount, filter, filtrate is for subsequent use;

(3) crude drug except Semen Arecae, Fructus Evodiae, Radix Eriobotryae, Radix Ginseng, Plumula Nelumbinis and Liquor Flos osmanthi Distillata is placed in medicine pot, add water and do not have powder 3-5cm, slow fire boiling three times, first time decocts 32-46 minute (preferably first time decocts 39 minutes), second time decocts 20-30 minute (preferably second time decocts 25 minutes), and third time decocts 14-26 minute (preferably third time decocts 20 minutes), merges three decocting liquids, three layers of cotton cloth filter, and filtrate is for subsequent use;

(4) joined in above-mentioned filtrate by the crude drug after step (1) and (2) process, add Liquor Flos osmanthi Distillata while stirring, mixing, dry heat sterilization, encapsulation, to obtain final product.

The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:

Fructus Evodiae: base is former: be rutaceae Fructus Evodiae, stone tiger and floating and thready pulse Fructus Evodiae green fruit.Pharmacological action: 1. drive ascarid effect: evodol extract has comparatively remarkable effect to ascaris suum in vitro; Also effective to Lumbricus, Hirudo.2. antibacterial action: Fructus Evodiae decoct (100%) has comparatively high inhibition effect (agar ditching flat band method) to vibrio cholera.10% water logging agent has inhibitory action to acrothesium floccosum in vitro; 1:3 water logging agent has suppression in various degree to 11 kinds of dermatophytess such as Microsporon audouinis.3. central action: a large amount of Fructus Evodiae has excitation to maincenter, and can cause visual disorder, illusion etc.4. other effects.Nature and flavor: arduous, temperature, poisonous.Gui Jing: enter liver, stomach warp.Function cures mainly: warming middle-JIAO, and pain relieving is regulated the flow of vital energy, dampness, and stopping vomiting is against acid regurgitation, and headache due to JUE YIN disorder, the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, abdominal pain during menstruation, Diarrhoea, vascular hypertension, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.

Plumula Nelumbinis: base is former: be the green plumule of the mature seed of nymphaeaceae plant lotus.Chemical analysis: containing liensinine, isoliensinine, (-)-Neferine, nuciferine, pronuciferine (+)-Pronuciferine, lotusin, methyl-corypalline, demethyl coclaurine.Again containing flavonoids such as cistus grass glycoside, hyperin, globulariacitrins.Nature and flavor: bitter, cold.Gui Jing: " book on Chinese herbal medicine is new again ": " enter the heart, lung, kidney three warp." function cures mainly: clear away heart-fire, reduce phlegm and internal heat, hemostasis, arresting seminal emission.Control vexed, thirsty, spit blood, seminal emission, conjunctival congestion and swelling pain.

Liquor Flos osmanthi Distillata: base is former: for the flower of Oleaceae plants sweet-scented osmanthus is through distillable liquid.Nature and flavor: micro-pungent; Micro-hardship; Warm in nature.Function cures mainly: depressed liver-energy dispersing and QI regulating; Being amusing, it is dirty to ward off; Improving eyesight; Wet one's whistle.Main depression of liver-QI; The breast side of body does not relax; Swelling of the gum; Toothache; Dry pharynx; Dry mouth; Halitosis.

Bullus Notholirionis Bulbuliferi: base is former: be the bulb of liliaceous plant Bulbus Notholirionis hyacinthini.Chemical analysis: bulb is containing steroid alkaloid: hyacinthoside first.Nature and flavor: pungent; Sweet; Bitter; Tepor.Function cures mainly: regulating qi-flowing for harmonizing stomach; Dispelling wind stopping cough.Main abdominal distention; Vomiting; Cough due to wind and cold.

Broken orchid root: base is former: be the root of labiate Rabdosia coesta.Nature and flavor: bitter in the mouth; Cool in nature.Function cures mainly: clearing away heat-damp and promoting diuresis; Promoting blood circulation and stopping pain.Main jaundice due to damp-heat; The pain over the hypochondriac region; Traumatic pain.

Radix Ginseng: base is former: be the root of Araliaceae Radix Ginseng.Nature and flavor: sweet micro-hardship, temperature.Gui Jing: enter spleen, lung meridian.Function cures mainly: strongly invigorating primordial QI, promotes the production of body fluid, calm the nerves Gu de-.Control impairment caused by overstrain deficient, lack of appetite, asthenia, food is told in regurgitation, stool lingering diarrhea, and empty cough with asthma is urged, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, and frequent micturition, quenches one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion, and prolonged deficiency is not multiple, the card of all qi-blood-body fluid deficiencies.

Radix Eriobotryae: base is former: be the seed of rosaceous plant Folium Eriobotryae.Chemical analysis: seed contains amygdalin, ceryl alcohol, aminoacid: 4-methylene-DL-proline, trans-4-methylol-D-PROLINE, cis-4-hydroxymethylproline, fatty acid, sterol.Hydrocyanic acid starch-containing and free again.Nature and flavor: bitter are flat.Gui Jing: " book on Chinese herbal medicine is new again ": " enter kidney channel." function cures mainly: preventing phlegm from forming and stopping coughing, depressed liver-energy dispersing and QI regulating.Control cough, hernia, edema, scrofula.

Phymatopsis griffithiana (Hook.) J. Sm.: base is former: be the herb of Plants of Polypodiaceae Phymatopsis integrifolia Ching.Nature and flavor: bitter; Cold; Nontoxic.Gui Jing: the heart; Large intestine; Small intestinal; Spleen channel.Function cures mainly: clearing away heat and cooling blood; Removing toxic substances and promoting subsidence of swelling.Main carbuncle and ulcer; Toxic swelling; Scrofula; Malignant boil; Sudden and violent red acute catarrhal conjunctivitis; Cough due to lung-heat; Stranguria; Discharging fresh blood stool.

Herba Arenariae Serpyllifoliae: base is former: for pinkwort is not in the mood for the herb of dish.Chemical analysis: herb contains vitexin, isovitexin, orientin, the multiple flavone component such as isorientin.Also containing 24-alkyl-△ 5-△ 7-steroidal compounds.Containing Palmic acid in seed oil, stearic acid, oleic acid, linoleic acid, the oleic acid wherein combined, linoleic acid content are up to 71% [3].Nature and flavor: bitter; Pungent; Cool in nature.Gui Jing: liver; Lung meridian.Function cures mainly: heat clearing away; Improving eyesight; Cough-relieving.Main liver-heat conjunctival congestion; Pterygium; Pulmonary tuberculosis cough; Laryngopharynx swelling and pain; Gingivitis.

Flos Caryophylli: base is former: be the alabastrum of plant clove of myrtaceae.Nature and flavor: pungent, temperature.Gui Jing: enter stomach, spleen, kidney channel.Function cures mainly: warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI.Control singultus, vomiting, regurgitation, dysentery, trusted subordinate's cold type of pain, mass beside the umbilicus, hernia, tinea disease.

Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.): base is former: be the thallus of the red abdomen Umbillcaria esculenta of Umbilicariaceae plant.Chemical analysis: thallus is containing gyrophoric acid, and black bitter edible plant stain is plain, methyl orsellinate and ethyl orsellinate, moss, methyl β-orcinolcarboxylate, usnic acid, two [(1,8-bis-base-3-methyl) mattress quinone] nature and flavor of 2,2-: micro-hardship; Property is put down.Gui Jing: stomach warp.Function cures mainly: stomach invigorating of regulating the flow of vital energy; Diuretic relieving distension.Main dyspepsia; Stomachache; Dysentery; Infantile malnutrition.

Radix Betae: base is former: be the root of Li section Zhi Wu Chard dish and preserved carrot.Chemical analysis: autumn excavates, cleans earth, using fresh herb or dry.Radix Betae is containing betanin, and choline, ferulic acid, oleanolic acid, sucrose contains 17.5%, glucose, fructose, Raffinose.Also containing pentosan, pectin, cellulose, starch, aminoacid, water soluble vitamins etc.Containing Radix Betae xanthin in root glue, Radix et Caulis Opuntiae Dillenii xanthin.Pharmacological action: the root effect of stimulating the menstrual flow, its effective ingredient claims betanidin, may be betanin, nontoxic to domestic animal; But under certain conditions (as after suffering various fungal infection), containing more nitrous acid or nitrate.Leaf, containing oxalic acid, potassium salt, also may produce cyanic acid; Domestic animal (as pig) eats it, sometimes can be poisoning.Herb is effective to ascaris mystax, and it is not containing globulariacitrin, also without antibacterial action.Nature and flavor: sweet; Property is put down.Function cures mainly: wide born of the same parents' therapeutic method to keep the adverse QI flowing downwards.Main born of the same parents' diaphragm feeling of distension and oppression.

Radix Wikstroemiae Dolichanthae: base is former: be the root of Isolated From Thymelaeaceae Species long flower Flos Wikstroemiae Dolichanthae.Nature and flavor: sweet; Property is put down.Gui Jing: spleen channel.Function cures mainly: alleviating distention in middle-JIAO is regulated the flow of vital energy; Spleen reinforcing stomach reinforcing.Main abdominal distention; Anorexia and loose stool; Edema due to deficiency does not disappear.

Semen Arecae: base is former: be the seed of babassu Semen Arecae.Chemical analysis: Semen Arecae is containing alkaloid 0.3～0。6%, condensed tannin 15%, fat 14% and areca red.Alkaloid master is arecoline, content 0.1～0。5%; All the other have arecaidine, demethyl arecaidine, guvacoline, arecolidine, homarecoline etc.It is high that raw areca contains biological alkali number than goods.Nature and flavor: toil, temperature.Gui Jing: enter spleen, stomach, large intestine channel.Function cures mainly: parasite killing, removing mass, the therapeutic method to keep the adverse QI flowing downwards, row water.Control malnutrition due to parasitic infestation, dyspepsia, abdominal distention, heavy after dysentery, malaria, edema, beriberi, accumulation of phlegm in the hypochondrium, crux.

Flos jasmini: base is former: be the dry flower of Oleaceae plants Flos jasmini.Chemical analysis:, gas aromatic person yellow with coloured gold is good.Containing linalool in Flos jasmini, phenylmethyl acetate, benzoic acid (Z)-3-vinyl acetate, LINL-OX, indole, jasmine lactone and methyl jasmonate.Congener Flos Jasmini alabastrum spends middle ingredient different with in full bloom.Main component in alabastrum is pohytol and linalool.The especially p-chavicol of aromatic compound is detected in open spending, also containing benzyl acetate in spending, and nerol, Geraniol, indole, 4-isopropyl acid methyl ester, hexenyl benzoate, trimethyl ten five-carbon ketone, isophytol, Cinnamyl Benzoate, acetic acid isophytol ester, Geraniol base Geraniol, acetic acid phytol ester and acetic acid Geraniol base Geraniol base Geraniol ester.Nature and flavor: micro-hardship; Property is put down.Gui Jing: Liver Channel.Function cures mainly: soothing liver-QI for relieving depression; Promoting the circulation of QI to relieve pain.Side of body rib gastral cavity abdomen caused by main stagnation of QI due to depression of the liver is had a pain; Dysentery is suffered from abdominal pain.

Petiolus nelumbinis: base is former: be petiole or the anthocaulus of nymphaeaceae plant lotus.Chemical analysis: Petiolus nelumbinis contains speckle Asia papaverine, the alkaloids such as miltanthin.In addition containing flavonoid glycoside, agedoite, resin and tannin.Nature and flavor: bitter; Property is put down.Gui Jing: spleen; Urinary bladder channel.Function cures mainly: expelling summer-heat heat clearing away; Regulating QI to expel dampness.Main heat-damp in summer is uncomfortable in chest does not relax; Have loose bowels; Dysentery; Gonorrhea; Leukorrhagia.

A kind of drug prescription science for the treatment of flatulence provided by the invention, the preparation method of various dosage form is simple, and products obtained therefrom is applicable to each age level patient and takes.In addition, excellent results of the present invention also shows:

1,the present invention uses theory of Chinese medical science to analyze prescription composition, and according to each physicochemical property of flavour of a drug ingredient and the result of study of pharmacological action, research obtains the preparation method of reasonable, stable active component;

2,this prescription, at dampness diuretic, while eliminating fire and detoxication, strengthens invigorating the spleen and benefiting QI, the merit of spleen reinforcing nourishing the stomach, has special efficacy, and have no side effect to treatment gastralgia, Nausea and vomiting, can not take food etc.;

3,medicine source is easy to get, and medical material is with low cost, can relieve patient ' s burden.

Detailed description of the invention

Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.

embodiment 1treat a medicament for flatulence, be prepared from by following bulk drugs, be weight portion (45g/ part): Fructus Evodiae 9 parts; Plumula Nelumbinis 10 parts; Liquor Flos osmanthi Distillata 8 parts; Bullus Notholirionis Bulbuliferi 9 parts; Broken orchid root 7 parts; Radix Ginseng 11 parts; Radix Eriobotryae 5 parts; Phymatopsis griffithiana (Hook.) J. Sm. 9 parts; Herba Arenariae Serpyllifoliae 8 parts; Flos Caryophylli 10 parts; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 6 parts; Radix Betae 10 parts; Radix Wikstroemiae Dolichanthae 6 parts; Semen Arecae 8 parts; Flos jasmini 7 parts; Petiolus nelumbinis 10 parts.

A kind of preparation method for the treatment of the pill of flatulence is:

(1) Radix Ginseng is put in medicine pot and is added cold water and do not have powder 1-3cm to soak 1 hour, then slow fire boiling 20 minutes, and filter, filtrate is for subsequent use;

(2) Fructus Evodiae, Radix Eriobotryae and Semen Arecae are mixed, the yellow wine adding 10% is mixed thoroughly, adds a cover vexed 6 minutes, takes out, and slow fire heating fried dry is degree, smashs into fine powder to pieces, for subsequent use; Plumula Nelumbinis is cleaned, and is together placed in hot pot with Flos Caryophylli, and slow fire heats, and dries, and smashs to pieces and porphyrize powder, for subsequent use;

(3) Bullus Notholirionis Bulbuliferi, broken orchid root, Phymatopsis griffithiana (Hook.) J. Sm., Herba Arenariae Serpyllifoliae, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Radix Betae, Radix Wikstroemiae Dolichanthae, Flos jasmini and Petiolus nelumbinis are placed in marmite, add the clear water of 7 times of raw material doses, slow fire heating decoction twice, first time decocts 20 minutes, second time decocts 16 minutes, merges twice decocting liquid, filters, filtrate reduced in volume to 80 DEG C relative density is the thick paste of 1.25, for subsequent use;

The instructions of taking of gained pill of the present invention is: every day three times, each 8-10 ball, and warm water takes, 10 days courses for the treatment of.

Model case: Zhao XX, man, 26 years old, people from Jinan.Readme: for many years, eat rear or angry postemphasis, and it is abnormal to defecate, each defecation all needs half an hour more than to gastral cavilty distension discomfort, painful abnormal, tired mind is depressed, once arrives local hospital treatment, DeGrain after taking medicine.Come my institute by colleague's introduction and check treatment.Check: patient's epigastric distending pain, time has the hiccups, belch, xerostomia, hunger but having no desire to eat.With insomnia, anxiety, red heat, soreness of waist symptom.Red tongue, has crackle, and thin fur is few, stringy and thready pulse.Gastroscopy is normal.Be diagnosed as flatulence.

Take a kind of pill for the treatment of flatulence of the present embodiment gained, instructions of taking: every day three times, each 8-10 ball, warm water takes, 10 days courses for the treatment of.After taking two courses for the treatment of, patient's flatulence obviously alleviates, the transference cure such as xerostomia, belch, and after continuing to take a course for the treatment of, patient's flatulence symptom resolution, self-induction is fully recovered, and drug withdrawal recovered after three months, without recurrence.

embodiment 2treat a medicament for flatulence, be prepared from by following bulk drugs, be weight portion (25g/ part): Fructus Evodiae 13 parts; Plumula Nelumbinis 15 parts; Liquor Flos osmanthi Distillata 12 parts; Bullus Notholirionis Bulbuliferi 15 parts; Broken orchid root 12 parts; Radix Ginseng 16 parts; Radix Eriobotryae 10 parts; Phymatopsis griffithiana (Hook.) J. Sm. 14 parts; Herba Arenariae Serpyllifoliae 14 parts; Flos Caryophylli 16 parts; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 12 parts; Radix Betae 13 parts; Radix Wikstroemiae Dolichanthae 12 parts; Semen Arecae 15 parts; Flos jasmini 13 parts; Petiolus nelumbinis 14 parts.

A kind of preparation method for the treatment of the capsule of flatulence is:

(1) Fructus Evodiae, broken orchid root, Radix Eriobotryae, Flos Caryophylli, Radix Wikstroemiae Dolichanthae and Semen Arecae are placed in traditional Chinese medicine drying machine, in 50 DEG C of dryings 2.5 hours, take out, are together ground into fine powder, are placed in penetrating bag, for subsequent use;

(2) the penetrating bag of step (1) gained is placed in hermetic container, adds dehydrated alcohol lixiviate 4 days, jolting every day period 4 times, collect lixiviating solution, three layers of cotton cloth filter, filtrate recycling ethanol, being evaporated to 65 DEG C of relative densities is the clear paste of 1.07-1.10, for subsequent use;

The preparation method of gained capsule of the present invention is: every day three times, each 3-5 grain, and warm water takes, 10 days courses for the treatment of.

embodiment 3treat a medicament for flatulence, be prepared from by following bulk drugs, be weight portion (40g/ part): Fructus Evodiae 10 parts; Plumula Nelumbinis 11 parts; Liquor Flos osmanthi Distillata 9 parts; Bullus Notholirionis Bulbuliferi 11 parts; Broken orchid root 8.5 parts; Radix Ginseng 12.5 parts; Radix Eriobotryae 6.5 parts; Phymatopsis griffithiana (Hook.) J. Sm. 10 parts; Herba Arenariae Serpyllifoliae 10 parts; Flos Caryophylli 12 parts; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 8 parts; Radix Betae 11 parts; Radix Wikstroemiae Dolichanthae 8 parts; Semen Arecae 10 parts; Flos jasmini 8.5 parts; Petiolus nelumbinis 11 parts.

A kind of preparation method for the treatment of the tablet of flatulence is:

(1) Radix Ginseng shave, dries, and is ground into fine powder, for subsequent use; Plumula Nelumbinis and the mixing of Semen Arecae sheet, the liquorice beverage adding 40% is mixed thoroughly, in steamer, steams supreme gas for degree, takes out, dry, smash into fine powder to pieces, for subsequent use;

(2) crude drug except Radix Ginseng, Plumula Nelumbinis, Semen Arecae sheet and Liquor Flos osmanthi Distillata is placed in Chinese medicament extracting device, with second alcohol and water for solvent (volume ratio of second alcohol and water is for 1:2), the amount of solvent is 5.5 times of raw material dose, heating and refluxing extraction 45 minutes, filter, filtrate recycling ethanol, being evaporated to 80 DEG C of relative densities is the thick paste of 1.20-1.23,78 DEG C of vacuum dryings, get dry extract powder, cool, porphyrize, for subsequent use;

(3) the raw material medicated powder after step (1) being processed and Liquor Flos osmanthi Distillata join in above-mentioned dried cream powder, add other adjuvant (adjuvant is the amylum pregelatinisatum of 11% raw material dose and the magnesium stearate of 6% raw material dose) while stirring, mixing, dry, be pressed into tablet, obtain final product.

The preparation method of gained tablet of the present invention is: every day three times, each 4-5 sheet, and warm water takes, 10 days courses for the treatment of.

embodiment 4treat a medicament for flatulence, be prepared from by following bulk drugs, be weight portion (30g/ part): Fructus Evodiae 12 parts; Plumula Nelumbinis 14 parts; Liquor Flos osmanthi Distillata 11 parts; Bullus Notholirionis Bulbuliferi 13 parts; Broken orchid root 10.5 parts; Radix Ginseng 14.5 parts; Radix Eriobotryae 8.5 parts; Phymatopsis griffithiana (Hook.) J. Sm. 13 parts; Herba Arenariae Serpyllifoliae 12 parts; Flos Caryophylli 14 parts; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 10 parts; Radix Betae 12 parts; Radix Wikstroemiae Dolichanthae 10 parts; Semen Arecae 13 parts; Flos jasmini 11.5 parts; Petiolus nelumbinis 13 parts.

A kind of preparation method for the treatment of the water preparation of flatulence is:

(1) getting Semen Arecae sheet puts in parch container, and slow fire heats, and stir-fries to coke yellow, for subsequent use; Fructus Evodiae and Radix Eriobotryae are placed in hermetic container, and the yellow wine adding 0.2 times amount stirs, vexed 10 minutes, take out, put in parch container, and little fire heating fried dry is degree, and taking-up cools, and is together placed in mortar with Semen Arecae sheet, is ground into fine powder, for subsequent use;

(2) Radix Ginseng and Plumula Nelumbinis are together put and are added cold water in medicine pot and do not have powder, slow fire boiling 50 minutes, and filter, filtrate is for subsequent use; It is swollen that Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) increases blister, extracts moisture, puts in hot pot, and the Oleum Brassicae campestris adding 20% times amount stir-fries 4.5 minutes, adds the boiled water slow fire boiling 16 minutes of 2 times amount, and filter, filtrate is for subsequent use;

(3) crude drug except Semen Arecae, Fructus Evodiae, Radix Eriobotryae, Radix Ginseng, Plumula Nelumbinis and Liquor Flos osmanthi Distillata is placed in medicine pot, add water and do not have powder 3-5cm, slow fire boiling three times, first time decocts 39 minutes, second time decocts 25 minutes, and third time decocts 20 minutes, merges three decocting liquids, three layers of cotton cloth filter, and filtrate is for subsequent use;

The instructions of taking of gained water preparation of the present invention is: twice daily, each 80-100mL, warmly takes, 10 days courses for the treatment of.

Model case: bavin XX, female, 46 years old, people from Zibo.Patient is to our hospital on August 11st, 2012.Readme: flatulence discomfort is had a surplus for 2 years, after the meal obviously, nearly half a year, health was obviously become thin.Once took western medicine, side effect causes stomach discomfort greatly, after change and take traditional Chinese medicine, have no improvement after treatment a period of time.Treatment is checked by making some inquiries about my institute.Check: patient's flatulence is not relaxed, xerostomia is not for drink.Usually be afraid of cold, few food is easily full, sleeps not good enough.Gastroscope is pointed out: chronic gastritis, pyloric insufficiency.

Take a kind of water preparation for the treatment of flatulence of the present embodiment gained, instructions of taking: twice daily, each 80-100mL, warmly to take, 10 days courses for the treatment of.After taking two courses for the treatment of, patient's flatulence obviously alleviates, and diet is normal, and sleep good, spirit is fully recovered after can continuing to take a course for the treatment of, Effect of follow-up visit by telephone after three months, without recurrence.

embodiment 5treat a medicament for flatulence, be prepared from by following bulk drugs, be weight portion (35g/ part): Fructus Evodiae 11 parts; Plumula Nelumbinis 12.5 parts; Liquor Flos osmanthi Distillata 10 parts; Bullus Notholirionis Bulbuliferi 12 parts; Broken orchid root 9.5 parts; Radix Ginseng 13.5 parts; Radix Eriobotryae 7.5 parts; Phymatopsis griffithiana (Hook.) J. Sm. 11.5 parts; Herba Arenariae Serpyllifoliae 11 parts; Flos Caryophylli 13 parts; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 9 parts; Radix Betae 11.5 parts; Radix Wikstroemiae Dolichanthae 9 parts; Semen Arecae 11.5 parts; Flos jasmini 10 parts; Petiolus nelumbinis 12 parts.

A kind of preparation method for the treatment of the pill of flatulence is:

(1) Radix Ginseng is put in medicine pot and is added cold water and do not have powder 1-3cm to soak 1.5 hours, then slow fire boiling 25 minutes, and filter, filtrate is for subsequent use;

(2) Fructus Evodiae, Radix Eriobotryae and Semen Arecae are mixed, the yellow wine adding 12% is mixed thoroughly, adds a cover vexed 8 minutes, takes out, and slow fire heating fried dry is degree, smashs into fine powder to pieces, for subsequent use; Plumula Nelumbinis is cleaned, and is together placed in hot pot with Flos Caryophylli, and slow fire heats, and dries, and smashs to pieces and porphyrize powder, for subsequent use;

(3) Bullus Notholirionis Bulbuliferi, broken orchid root, Phymatopsis griffithiana (Hook.) J. Sm., Herba Arenariae Serpyllifoliae, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Radix Betae, Radix Wikstroemiae Dolichanthae, Flos jasmini and Petiolus nelumbinis are placed in marmite, add the clear water of 8 times of raw material doses, slow fire heating decoction twice, first time decocts 30 minutes, second time decocts 22 minutes, merges twice decocting liquid, filters, filtrate reduced in volume to 80 DEG C relative density is the thick paste of 1.26, for subsequent use;

test example 1a kind of clinical practice for the treatment of the medicament (embodiment 5) of flatulence of gained of the present invention:

1, physical data

In April, 2010, in JIUYUE ,-2013, screened 336 routine flatulence patients in 4 hospitals, wherein male 179 example, women 157 example, the age 23-66 year, the course of disease is-7 years half a year.

2, Symptoms

Flatulence patients is that how irregular Upper abdominal pain is, is generally diffusivity epigastrium causalgia, dull pain, distending pain etc.; Because of achlorhydria, the factors such as gastric fermentation gas make gastric gas accumulation, cause belch to occur.Meanwhile, there is the symptom such as inappetence, nausea and vomiting, constipation in patient.

3, Therapeutic Method

All patients are divided into two groups at random, experimental group and matched group.Two groups of patients no significant difference (P > 0.05) in age, sex, the course of disease.Experimental group takes products obtained therefrom of the present invention, instructions of taking: every day three times, each 8-10 ball, and warm water takes, 10 days courses for the treatment of.Matched group takes other medicine (as conventional medication such as XIANGSHA LIUJU WAN, Pingwei pill, west spring mouth reservoir).Treat three courses for the treatment of altogether.

4, efficacy assessment standard

Recovery from illness: flatulence transference cure, body constitution recovers normal, observes half a year without recidivist;

Effective: flatulence symptom partial disappearance or obviously alleviate, body constitution recovers normal;

Take a turn for the better: flatulence symptom is alleviated to some extent, but does not reach effective person;

Invalid: flatulence symptom is without improvement or aggravation.

Total effective rate=(recovery from illness example+effective example+improvement example)/total inspection case load × 100%.

5, therapeutic effect

The therapeutic outcome of two groups of patients is as shown in table 1.

Table 1: the therapeutic outcome of experimental group and matched group patient compares

Therapeutic effect: experimental group cures 150 examples (68.8%), effective 49 examples (22.5%), 16 examples that take a turn for the better (7.3%), invalid 3 examples, total effective rate 98.6%.The therapeutic effect of experimental group is obviously better than matched group.

The present invention select Fructus Evodiae, Plumula Nelumbinis, Liquor Flos osmanthi Distillata, Bullus Notholirionis Bulbuliferi, broken orchid root, Radix Ginseng, Radix Eriobotryae, Phymatopsis griffithiana (Hook.) J. Sm. and Herba Arenariae Serpyllifoliae etc. totally 16 taste primary raw material medicines be prepared from.Fang Zhong, Fructus Evodiae warming middle-JIAO, pain relieving, regulates the flow of vital energy; Plumula Nelumbinis clears away heart-fire, and reduces phlegm and internal heat; Liquor Flos osmanthi Distillata depressed liver-energy dispersing and QI regulating; Being amusing, it is dirty to ward off; Broken orchid root clearing away heat-damp and promoting diuresis; Promoting blood circulation and stopping pain; Flos Caryophylli warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI; The wide born of the same parents' therapeutic method to keep the adverse QI flowing downwards of Radix Betae; Radix Wikstroemiae Dolichanthae alleviating distention in middle-JIAO is regulated the flow of vital energy, spleen reinforcing stomach reinforcing; The heat clearing away of Petiolus nelumbinis expelling summer-heat, regulating QI to expel dampness.All medicines share, and complement each other, and reach regulating qi-flowing for strengthening spleen, fall pain relieving of vomitting, dampness diuretic, spleen reinforcing nourishing the stomach, repair the therapeutic purposes of internal organs trauma.Take 3 courses for the treatment of in experimental group, effective percentage is 98.6%, and matched group is only 81.4%.

It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims

1. treat a medicament for flatulence, it is characterized in that, be prepared from by following bulk drugs, be weight portion: Fructus Evodiae 9-13; Plumula Nelumbinis 10-15; Liquor Flos osmanthi Distillata 8-12; Bullus Notholirionis Bulbuliferi 9-15; Broken orchid root 7-12; Radix Ginseng 11-16; Radix Eriobotryae 5-10; Phymatopsis griffithiana (Hook.) J. Sm. 9-14; Herba Arenariae Serpyllifoliae 8-14; Flos Caryophylli 10-16; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 6-12; Radix Betae 10-13; Radix Wikstroemiae Dolichanthae 6-12; Semen Arecae 8-15; Flos jasmini 7-13; Petiolus nelumbinis 10-14.

2. a kind of medicament for the treatment of flatulence as claimed in claim 1, is characterized in that, be prepared from by following bulk drugs, be weight portion: Fructus Evodiae 10-12; Plumula Nelumbinis 11-14; Liquor Flos osmanthi Distillata 9-11; Bullus Notholirionis Bulbuliferi 11-13; Broken orchid root 8.5-10.5; Radix Ginseng 12.5-14.5; Radix Eriobotryae 6.5-8.5; Phymatopsis griffithiana (Hook.) J. Sm. 10-13; Herba Arenariae Serpyllifoliae 10-12; Flos Caryophylli 12-14; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 8-10; Radix Betae 11-12; Radix Wikstroemiae Dolichanthae 8-10; Semen Arecae 10-13; Flos jasmini 8.5-11.5; Petiolus nelumbinis 11-13.

3. a kind of medicament for the treatment of flatulence as claimed in claim 1, is characterized in that, be prepared from by following bulk drugs, be weight portion: Fructus Evodiae 11; Plumula Nelumbinis 12.5; Liquor Flos osmanthi Distillata 10; Bullus Notholirionis Bulbuliferi 12; Broken orchid root 9.5; Radix Ginseng 13.5; Radix Eriobotryae 7.5; Phymatopsis griffithiana (Hook.) J. Sm. 11.5; Herba Arenariae Serpyllifoliae 11; Flos Caryophylli 13; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 9; Radix Betae 11.5; Radix Wikstroemiae Dolichanthae 9; Semen Arecae 11.5; Flos jasmini 10; Petiolus nelumbinis 12.

4. a kind of medicament for the treatment of flatulence as described in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable pill, preparation method is as follows:

5. a kind of preparation method for the treatment of the pill of flatulence according to claim 4, is characterized in that, the time of soaking in step (1) is 1-2 hour (the preferred time of soaking is 1.3-1.7 hour, and the time of the immersion be more preferably is 1.5 hours).

6. a kind of medicament for the treatment of flatulence as described in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable capsule, preparation method is as follows:

7. a kind of preparation method for the treatment of the capsule of flatulence according to claim 6, is characterized in that, in step (2), the time of lixiviate is 2-6 days (time of preferred lixiviate is 3-5 days, and the time of the lixiviate be more preferably is 4 days).

8. a kind of medicament for the treatment of flatulence as described in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable tablet, preparation method is as follows:

9. a kind of preparation method for the treatment of the tablet of flatulence according to claim 8, is characterized in that, adjuvant described in step (3) is the amylum pregelatinisatum of 11% raw material dose and the magnesium stearate of 6% raw material dose.

10. a kind of medicament for the treatment of flatulence as described in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable water preparation, preparation method is as follows: