CN105130997A - 一种库潘尼西的制备方法 - Google Patents

一种库潘尼西的制备方法 Download PDF

Info

Publication number
CN105130997A
CN105130997A CN201510617987.6A CN201510617987A CN105130997A CN 105130997 A CN105130997 A CN 105130997A CN 201510617987 A CN201510617987 A CN 201510617987A CN 105130997 A CN105130997 A CN 105130997A
Authority
CN
China
Prior art keywords
kupannixi
reaction
amino
yl
method
Prior art date
Application number
CN201510617987.6A
Other languages
English (en)
Chinese (zh)
Other versions
CN105130997B (zh
Inventor
许学农
Original Assignee
苏州明锐医药科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 苏州明锐医药科技有限公司 filed Critical 苏州明锐医药科技有限公司
Priority to CN201510617987.6A priority Critical patent/CN105130997B/zh
Publication of CN105130997A publication Critical patent/CN105130997A/zh
Application granted granted Critical
Publication of CN105130997B publication Critical patent/CN105130997B/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
CN201510617987.6A 2015-09-25 2015-09-25 一种库潘尼西的制备方法 CN105130997B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510617987.6A CN105130997B (zh) 2015-09-25 2015-09-25 一种库潘尼西的制备方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510617987.6A CN105130997B (zh) 2015-09-25 2015-09-25 一种库潘尼西的制备方法

Publications (2)

Publication Number Publication Date
CN105130997A true CN105130997A (zh) 2015-12-09
CN105130997B CN105130997B (zh) 2017-12-05

Family

ID=54716624

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510617987.6A CN105130997B (zh) 2015-09-25 2015-09-25 一种库潘尼西的制备方法

Country Status (1)

Country Link
CN (1) CN105130997B (und)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017049983A1 (zh) * 2015-09-25 2017-03-30 苏州立新制药有限公司 库潘尼西的制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1688582A (zh) * 2002-09-30 2005-10-26 拜尔药品公司 稠合吡咯-嘧啶衍生物
CN101631464A (zh) * 2006-12-05 2010-01-20 拜耳先灵医药股份有限公司 用于治疗过度增殖疾病和血管发生相关性疾病的2,3-二氢咪唑并[1,2-c]喹唑啉取代衍生物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1688582A (zh) * 2002-09-30 2005-10-26 拜尔药品公司 稠合吡咯-嘧啶衍生物
CN101631464A (zh) * 2006-12-05 2010-01-20 拜耳先灵医药股份有限公司 用于治疗过度增殖疾病和血管发生相关性疾病的2,3-二氢咪唑并[1,2-c]喹唑啉取代衍生物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
C. BALAKUMAR,等: "Synthesis, anti-in flammatory evaluation and docking studies of some new fluorinated fused quinazolines", 《EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY》 *
CESAR MENDOZA-MARTÍNEZ,等: "Antileishmanial activity of quinazolin e derivatives: Synthesis, docking screens, molecular dynamic simulations and electrochemical studies", 《EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017049983A1 (zh) * 2015-09-25 2017-03-30 苏州立新制药有限公司 库潘尼西的制备方法

Also Published As

Publication number Publication date
CN105130997B (zh) 2017-12-05

Similar Documents

Publication Publication Date Title
DE60319820T2 (de) Pyrazoloä1,5-aüpyrimidin-verbindungen als antivirale agentien
AU2002337047B8 (en) Novel dihydropteridinones, method for producing the same and the use thereof as medicaments
EP3057969B1 (en) Compositions useful for treating disorders related to kit
Wu et al. ‘One-pot’nitro reduction–cyclisation solid phase route to benzimidazoles
EP2464647B1 (en) Azaindazoles as btk kinase modulators and use thereof
JP4631703B2 (ja) ピリミジン−4−オン化合物の製造方法
WO1999051582A1 (fr) Composes heterocycliques azotes
CN101346357A (zh) 氨基二氢噻嗪衍生物
EP2709989A1 (en) Quinazoline derivatives for the treatment of viral infections and further diseases
CA2453664A1 (en) Process for preparation of amidine derivatives
WO2008104077A1 (en) Small molecule inhibitors of protein arginine methyltransferases (prmts)
EP1458688A1 (en) Quinazolinone derivative
PT99415A (pt) Processo para a preparacao de derivados de quinazolina uteis para melhorar a activadede antitumoral
CA2917667A1 (en) Kinase inhibitors for the treatment of disease
KR20100081294A (ko) 간염과 같은 바이러스성 감염 치료용 이미다조[1,2-a] 피라진 화합물
DE60310767T2 (de) PYRAZOL-3,4-d-PYRIMIDINDERIVATE UND IHRE VERWENDUNG BEI DER BEHANDLUNG VON H.PYLORI-INFEKTIONEN
Baraldi et al. Synthesis of new pyrazolo [4, 3-e]-1, 2, 4-triazolo [1, 5-c] pyrimidines and related heterocycles
Xu et al. Synthesis of novel 1, 3-diaryl pyrazole derivatives bearing rhodanine-3-fatty acid moieties as potential antibacterial agents
EP2305667A2 (en) Nilotinib intermediates and preparation thereof
US20130131057A1 (en) New bicyclic compounds as pi3-k and mtor inhibitors
WO2014128655A1 (en) Substituted imidazo[4,5-c]quinoline derivatives as bromodomain inhibitors
US8592430B2 (en) Quinazolin-oxime derivatives as Hsp90 inhibitors
AU2009320683A1 (en) Pyridine-3-carboxyamide derivative
FI66180C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 6-acylaminotetrahydro-1,3,5-triazin-2,4-dioner
NZ596025A (en) [4-(6-halo-7-substituted-2,4-dioxo-1,4-dihydro-2h-quinazolin-3-yl)-phenyl]-5-chloro-thiophen-2-yl-sulfonylureas and forms and methods related thereto

Legal Events

Date Code Title Description
C06 Publication
C10 Entry into substantive examination
GR01 Patent grant