CN105130997A - 一种库潘尼西的制备方法 - Google Patents

一种库潘尼西的制备方法 Download PDF

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Publication number
CN105130997A
CN105130997A CN201510617987.6A CN201510617987A CN105130997A CN 105130997 A CN105130997 A CN 105130997A CN 201510617987 A CN201510617987 A CN 201510617987A CN 105130997 A CN105130997 A CN 105130997A
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China
Prior art keywords
kupannixi
reaction
amino
yl
method
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CN201510617987.6A
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English (en)
Chinese (zh)
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CN105130997B (zh
Inventor
许学农
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苏州明锐医药科技有限公司
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Publication of CN105130997A publication Critical patent/CN105130997A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
CN201510617987.6A 2015-09-25 2015-09-25 一种库潘尼西的制备方法 CN105130997B (zh)

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CN201510617987.6A CN105130997B (zh) 2015-09-25 2015-09-25 一种库潘尼西的制备方法

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CN201510617987.6A CN105130997B (zh) 2015-09-25 2015-09-25 一种库潘尼西的制备方法

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CN105130997A true CN105130997A (zh) 2015-12-09
CN105130997B CN105130997B (zh) 2017-12-05

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CN201510617987.6A CN105130997B (zh) 2015-09-25 2015-09-25 一种库潘尼西的制备方法

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017049983A1 (zh) * 2015-09-25 2017-03-30 苏州立新制药有限公司 库潘尼西的制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1688582A (zh) * 2002-09-30 2005-10-26 拜尔药品公司 稠合吡咯－嘧啶衍生物
CN101631464A (zh) * 2006-12-05 2010-01-20 拜耳先灵医药股份有限公司 用于治疗过度增殖疾病和血管发生相关性疾病的2,3-二氢咪唑并[1,2-c]喹唑啉取代衍生物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1688582A (zh) * 2002-09-30 2005-10-26 拜尔药品公司 稠合吡咯－嘧啶衍生物
CN101631464A (zh) * 2006-12-05 2010-01-20 拜耳先灵医药股份有限公司 用于治疗过度增殖疾病和血管发生相关性疾病的2,3-二氢咪唑并[1,2-c]喹唑啉取代衍生物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
C. BALAKUMAR，等: "Synthesis, anti-in flammatory evaluation and docking studies of some new fluorinated fused quinazolines", 《EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY》 *
CESAR MENDOZA-MARTÍNEZ，等: "Antileishmanial activity of quinazolin e derivatives: Synthesis, docking screens, molecular dynamic simulations and electrochemical studies", 《EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017049983A1 (zh) * 2015-09-25 2017-03-30 苏州立新制药有限公司 库潘尼西的制备方法

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