CN105031363A - Prescription for treating toothache and preparation method thereof - Google Patents

Prescription for treating toothache and preparation method thereof Download PDF

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CN105031363A
CN105031363A CN201510531507.4A CN201510531507A CN105031363A CN 105031363 A CN105031363 A CN 105031363A CN 201510531507 A CN201510531507 A CN 201510531507A CN 105031363 A CN105031363 A CN 105031363A
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岳源
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Abstract

The invention discloses a prescription for treating toothache. The prescription is prepared from the following medicinal raw materials in parts by mass: 12-18 parts of sweet-scented osmanthus, 10-14 parts of large-leaved chrysosplenium, 3-6 parts of cirald daphne bark, 8-14 parts of changnienia amoena chien, 9-13 parts of himalayan maple, 7-12 parts of prostrate cyathula, 10-13 parts of commelina hengalensis, 8-15 parts of Chinese starjasmine stem, 11-14 parts of sheareria nana, 7-13 parts of acajounut, 9-14 parts of gooseintestine sarwort herb, 6-12 parts of berberis polyantha, 8-16 parts of Tibet lancea herb, 10-16 parts of phaphidophora peepla, and 8-13 parts of chrysopogon aciculatus. The prescription is prepared by the conclusion of years of practice, has the effects of removing stasis, relieving pain, clearing heat and removing toxicity, and has a remarkable curative effect.

Description

Cure prescription and the preparation method of toothache
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to the prescription and preparation method of curing toothache.
Background technology
Toothache is one of modal symptom of department of stomatology odontopathy, and it shows as red swelling of gingiva, meets caloric stimulation pain, buccal swelling etc.Toothache mostly cause dental pulp dental nerve by gingivitis, periodontitis, decayed tooth or Fractured teeth) infection caused by.The traditional Chinese medical science thinks that toothache is caused by the reasons such as diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, excessiveness of stomach-fire, hyperactivity of fire of suffering from a deficiency of the kidney, worm-eaten tooth.Gingiva is scarlet or purplish red, swelling, soft, gum edge has erosion or internal bud hamartoplasia to turn up sometimes, and when brushing teeth or eat, gingiva is easily hemorrhage, but general without hematostaxis, and patient is without obvious subjective symptoms, and sometimes can have sense of itching or swell, halitosis is obvious.
Publication No. CN104324248A(application number 201410566241.2) Chinese patent literature disclose a kind of Chinese medicine for the treatment of toothache, comprise component A and B component, component A is formed by following composition proportion: Radix Ophiopogonis, Rhizoma Et Radix Notopterygii, Radix Adenophorae (Radix Glehniae), Ramulus Uncariae Cum Uncis, Rhizoma Gastrodiae, Plumula Nelumbinis, Radix Gentianae, Radix Et Rhizoma Rhei, Herba Taraxaci; B component is formed by following composition proportion: Borneolum Syntheticum, Herba Rosmarini Officinalis, Rhizoma Cyperi, Radix Dipsaci, Flos Carthami.Publication No. CN104398761A(application number 201410588285.5) Chinese patent literature disclose a kind of Chinese medicine for the treatment of toothache, it is characterized in that being made up of the crude drug of following percentage by weight: Fructus Solani Lyrati 10 ~ 13%, Rhizoma Cimicifugae 9 ~ 12%, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 6 ~ 9%, motherwort 4 ~ 6%, graceful Fructus Vitics Simplicifoliae 5 ~ 8%, Herba Polygoni Avicularis 6 ~ 9%, Semen Allii Tuberosi 5 ~ 8%, Valeriana officinalis var. latifolia 4 ~ 6%, Caulis et folium pavettae hongkongensis 4 ~ 7%, CitrusaurantiumL.Var.amara Engl. 4 ~ 8%, geranium 3 ~ 5%, Herba Sedi Multicaulis 4 ~ 8%, Herba Verbenae 5 ~ 8%, water vertebra wood 5 ~ 8%, Caulis Spatholobi 3 ~ 6%.Publication No. CN102973773A(application number 201210511955.4) Chinese patent literature disclose a kind of Yatongsan powder for curing toothache, comprise the raw material of following mass fraction: Rhizoma Coptidis 20-40 part, Pericarpium Zanthoxyli 10-20 part, Fructus Xanthii 12-18 part, Radix Scrophulariae 8-12 part, Rhizoma Anemarrhenae 6-12 part, Radix Rehmanniae 5-11 part, Flos Caryophylli 4-8 part, Herba Asari 6-8 part, Radix Bupleuri 8-10 part, Fructus Gardeniae 10-14 part, Radix Gentianae 10-12 part.
The medicine being used for the treatment of toothache is at present main mainly with antibiotic and analgesic, can only relief of symptoms, thoroughly can not effect a radical cure, long-term taking, cause comparatively major injury to the health of patient, therefore need to develop one Chinese medicine formula safely and effectively.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take prescription and the preparation method of the wide treatment toothache of safe and applicable.
Technical scheme of the present invention is:
Cure the prescription of toothache, be prepared from primarily of following bulk drugs, be mass parts: Flos Osmanthi Fragrantis 12-18; Herba Chrysosplenii Macrophylli 10-14; Daphne giraldii Nitsche 3-6; Changuienia amoena Chien 8-14; Moth tree 9-13; Herba Cyathulae Prostratae 7-12; Horse Auricled Hedyotis Herb 10-13; Caulis Trachelospermi 8-15; Herba Sheareriae 11-14; Fructus anacardii 7-13; Herba Stellariae Neglectae 9-14; CIHUANQIN 6-12; Herba Lanceae Tibeticae 8-16; great Ye south Soviet Union 10-16; Herba Chrysopogonis Aciculati 8-13.
Preferred version is, Flos Osmanthi Fragrantis 14-16; Herba Chrysosplenii Macrophylli 11-13; Daphne giraldii Nitsche 4-5; Changuienia amoena Chien 10-12; Moth tree 10-12; Herba Cyathulae Prostratae 9-10; Horse Auricled Hedyotis Herb 11-12; Caulis Trachelospermi 10-13; Herba Sheareriae 12-13; Fructus anacardii 9-11; Herba Stellariae Neglectae 11-12; CIHUANQIN 8-10; Herba Lanceae Tibeticae 10-14; great Ye south Soviet Union 12-14; Herba Chrysopogonis Aciculati 9-12.
More preferably, Flos Osmanthi Fragrantis 15; Herba Chrysosplenii Macrophylli 12; Daphne giraldii Nitsche 4.5; Changuienia amoena Chien 11; Moth tree 11; Herba Cyathulae Prostratae 9.5; Horse Auricled Hedyotis Herb 11.5; Caulis Trachelospermi 11.5; Herba Sheareriae 12.5; Fructus anacardii 10; Herba Stellariae Neglectae 11.5; CIHUANQIN 9; Herba Lanceae Tibeticae 12; great Ye south Soviet Union 13; Herba Chrysopogonis Aciculati 10.5.
The prescription of described treatment toothache, be made into pharmaceutically acceptable soft extract, its preparation method is:
(1) get Herba Chrysosplenii Macrophylli, Changuienia amoena Chien, Herba Cyathulae Prostratae, horse Auricled Hedyotis Herb, Herba Sheareriae, Herba Stellariae Neglectae and Herba Lanceae Tibeticae to clean, chopping, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times) to decoct, big fire is heated to boiling, turns little fire and decocts 12-26 minute (preferably: turn little fire and decoct 16-22 minute; Be more preferably: turn little fire and decoct 19 minutes), filter, collect filtrate;
(2) get moth tree and Fructus anacardii removing impurity, be placed in container, add refined honey water infiltration 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(3) get Daphne giraldii Nitsche, CIHUANQIN, large Ye Nansu and Herba Chrysopogonis Aciculati and clean remove impurity, add water and soaking in rice vinegar 20-30 minute (preferred: to soak 22-28 minute; Be more preferably: soak 25 minutes), moderate heat boils and is sucked to vinegar liquid, and taking-up is dried, cutting;
(4) Flos Osmanthi Fragrantis and Caulis Trachelospermi are cleaned remove impurity, be cut into thread, be placed in hot pot, moderate heat stir-fries black to surperficial zoom, and drench into rice vinegar after closing fire, go out most Mars, moistening 3 minutes, takes out;
(5) pulverized by made to step (2) (3) (4) crude drug, be added in step (1) gained filtrate, heating is concentrated into clear paste, obtains soft extract.
The preparation method of the prescription soft extract of described treatment toothache, the amount that step (2) adds refined honey water was as the criterion there not to be crude drug 1cm.
The prescription of described treatment toothache, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Herba Chrysosplenii Macrophylli, Changuienia amoena Chien, Herba Cyathulae Prostratae, horse Auricled Hedyotis Herb, Herba Sheareriae, Herba Stellariae Neglectae and Herba Lanceae Tibeticae to clean, shred, decoct with water, big fire is heated to boiling, turns little fire and decocts 12-26 minute (preferably: turn little fire and decoct 16-22 minute; Be more preferably: turn little fire and decoct 19 minutes), filter, collect filtrate;
(2) get moth tree and Fructus anacardii removing impurity, be placed in container, add refined honey water and do not have crude drug 1cm to infiltrate 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(3) get Daphne giraldii Nitsche, CIHUANQIN, large Ye Nansu and Herba Chrysopogonis Aciculati and clean remove impurity, add water and soaking in rice vinegar 20-30 minute (preferred: to soak 22-28 minute; Be more preferably: soak 25 minutes), moderate heat boils and is sucked to vinegar liquid, and taking-up is dried, cutting;
(4) Flos Osmanthi Fragrantis and Caulis Trachelospermi are cleaned remove impurity, be cut into thread, be placed in hot pot, moderate heat stir-fries black to surperficial zoom, and drench into rice vinegar after closing fire, go out most Mars, moistening 3 minutes, takes out;
(5) pulverized by made to step (2) (3) (4) crude drug, be added in step (1) gained filtrate, heating is boiled to boiling, after filtration, collects filtrate, obtains decoction.
The preparation method of the prescription decoction of described treatment toothache, the 6-9 that step (1) amount of water is boiled crude drug quality is doubly (preferred: the 7-8 that amount of water is boiled crude drug quality is doubly; Be more preferably: amount of water is 7.5 times of boiled crude drug quality).
The prescription of described treatment toothache, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Herba Chrysosplenii Macrophylli, Changuienia amoena Chien, Herba Cyathulae Prostratae, horse Auricled Hedyotis Herb, Herba Sheareriae, Herba Stellariae Neglectae and Herba Lanceae Tibeticae to clean, chopping, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times) to decoct, big fire is heated to boiling, turns little fire and decocts 12-26 minute (preferably: turn little fire and decoct 16-22 minute; Be more preferably: turn little fire and decoct 19 minutes), filter, collect filtrate;
(2) get moth tree and Fructus anacardii removing impurity, be placed in container, add refined honey water and do not have crude drug 1cm to infiltrate 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(3) get Daphne giraldii Nitsche, CIHUANQIN, large Ye Nansu and Herba Chrysopogonis Aciculati and clean remove impurity, add water and soaking in rice vinegar 20-30 minute (preferred: to soak 22-28 minute; Be more preferably: soak 25 minutes), moderate heat boils and is sucked to vinegar liquid, and taking-up is dried, cutting;
(4) Flos Osmanthi Fragrantis and Caulis Trachelospermi are cleaned remove impurity, be cut into thread, be placed in hot pot, moderate heat stir-fries black to surperficial zoom, and drench into rice vinegar after closing fire, go out most Mars, moistening 3 minutes, takes out;
(5) spray drying step (1) gained filtrate, pulverizes and sieves dry thing, obtains powder together with step (2) (3) (4) made crude drug.
The preparation method of the prescription powder of described treatment toothache, it is (preferred: to pulverize 140-160 mesh sieve that step (5) pulverized 120-180 mesh sieve; Be more preferably: pulverized 150 mesh sieves).
The prescription of described treatment toothache, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get Herba Chrysosplenii Macrophylli, Changuienia amoena Chien, Herba Cyathulae Prostratae, horse Auricled Hedyotis Herb, Herba Sheareriae, Herba Stellariae Neglectae and Herba Lanceae Tibeticae to clean, chopping, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times) to decoct, big fire is heated to boiling, turns little fire and decocts 12-26 minute (preferably: turn little fire and decoct 16-22 minute; Be more preferably: turn little fire and decoct 19 minutes), filter, collect filtrate;
(2) get moth tree and Fructus anacardii removing impurity, be placed in container, add refined honey water and do not have crude drug 1cm to infiltrate 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(3) get Daphne giraldii Nitsche, CIHUANQIN, large Ye Nansu and Herba Chrysopogonis Aciculati and clean remove impurity, add water and soaking in rice vinegar 20-30 minute (preferred: to soak 22-28 minute; Be more preferably: soak 25 minutes), moderate heat boils and is sucked to vinegar liquid, and taking-up is dried, cutting;
(4) Flos Osmanthi Fragrantis and Caulis Trachelospermi are cleaned remove impurity, be cut into thread, be placed in hot pot, moderate heat stir-fries black to surperficial zoom, and drench into rice vinegar after closing fire, go out most Mars, moistening 3 minutes, takes out;
(5) pulverized by made to step (2) (3) (4) crude drug, be added in step (1) gained filtrate, heating is concentrated into thick paste, and oven dry pulverizes and sieves, and is packed in capsule, obtains capsule.
The preparation method of the prescription capsule of described treatment toothache, it is (preferred: to pulverize 60-90 mesh sieve that step (5) pulverized 40-110 mesh sieve; Be more preferably: pulverized 75 mesh sieves).
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Flos Osmanthi Fragrantis: base is former: be the flower of Oleaceae plants sweet-scented osmanthus.Nature and flavor: pungent, temperature.Function cures mainly: reduce phlegm, dissipating blood stasis.Control phlegm retention to ridicule and cough, hemorrhoidal hamorrhage dysentery, hernia abdominal mass, toothache, halitosis.
Herba Chrysosplenii Macrophylli: base is former: be the herb of saxifragaceae plant great Ye gold waist.Nature and flavor: bitter in the mouth, puckery, cold in nature.Function cures mainly: heat-clearing and toxic substances removing, cough-relieving, leukorrhagia stopping, convergence granulation promoting.Main ecthyma; Scald.
Daphne giraldii Nitsche: base is former: be root bark and the peel of stem of Isolated From Thymelaeaceae Species Daphne Giraldii Nitsche.Nature and flavor: bitter, pungent, temperature.Slightly poisonous.Function cures mainly: dispelling wind and removing obstruction in the collateral, stasis-dispelling and pain-killing.For headache, toothache, rheumatic arthritis, traumatic injury, stomachache, pain in the hepatic region.
Changuienia amoena Chien: base is former: be pseudobulb and the herb of orchid Herba Changnieniae amoenae.Nature and flavor: bitter in the mouth; Cold in nature.Function cures mainly: heat clearing away; Removing heat from blood; Removing toxic substances.Main cough; Sputum mixed with blood; Furuncle furuncle.
Moth is set: base is former: the twig and the fruit that split Pueraria lobota trailing plants maple for Aceraceae plant is long.Nature and flavor: bitter; Salty; Flat.Function cures mainly: antiinflammatory, antitussive.Main new chronic cough is coughed; Thrush.
Herba Cyathulae Prostratae: base is former: be the aerial parts of amaranthaceous plant Herba Cyathulae Prostratae.Nature and flavor: bitter; Cool in nature.Function cures mainly: heat-clearing and toxic substances removing; Promoting blood circulation to remove blood stasis.Main carbuncle pyogenic infections from tumour or sore; Venom; Traumatic injury congestive edema.
Horse Auricled Hedyotis Herb: base is former: be the herb of Commeline communis section Commeline communis platymiscium meal bag grass.Composition: herb contains positive seven days eight alcohol, myricyl alcohol, positive laccerol, stigmasterol ,-sitosterol, campesterol and benzyladenine etc.The property of medicine: bitter, cold.Function cures mainly: heat-clearing and toxic substances removing, inducing diuresis to remove edema.Cure mainly calentura heating, excessive thirst, laryngopharynx swelling and pain, hematodiarrhoea, pyretic stranguria, hemorrhoid, furuncle carbuncle, snake bite and insect sting.
Caulis Trachelospermi: base is former: be stem, the leaf of apocynaceae plant trachelospermum jasminoide.Chemical analysis: stem is containing arctigenin, tracheloside, matairesinoside, nortracheloside, dambonitol, cupreol glycoside, cymarose etc.Nature and flavor: bitter, cool.Gui Jing: enter liver, kidney channel.Function cures mainly: dispel the wind, dredging collateral, hemostasis, repercussive.Dispelling the wind and dampness pathogens arthralgia pain, the contracture of muscle arteries and veins, carbuncle, sore throat, spits blood, traumatic injury, disease that postpartum lochia can't go.
Herba Sheareriae: base is former: be the herb of feverfew Herba Sheareriae.Summer, autumn gather.Nature and flavor: bitter are flat.Function cures mainly: heat-clearing and toxic substances removing, inducing diuresis to remove edema, dispelling wind.
Fructus anacardii: base is former: be the fruit of Anacardiaceae plant chicken Fructus anacardii.Nature and flavor: sweet; Flat.Gui Jing: lung meridian.Function cures mainly: nourishing the lung to arrest cough; Quench the thirst; Relieving restlessness.Main cough with dyspnea; Vexed; Thirsty.
Herba Stellariae Neglectae: base is former: be the herb of pinkwort match Herba stellariae mediae.Nature and flavor: micro-hardship; Cool in nature.Gui Jing: stomach; The heart; Liver Channel.Function cures mainly: heat-clearing and toxic substances removing; Treating stranguria; Blood stasis dispelling.Main sick pyogenic infections from tumour or sore; Scall; Mastalgia; Hemorrhoid; Dysentery; Toothache; Pyretic stranguria; Puerperal abdonimal pain.
CIHUANQIN: base is former: be the Herb of Berberidaceae plant mahonia fargesii Takeda.Nature and flavor: bitter; Cold.Function cures mainly: heat clearing away; Dampness; Removing toxic substances.Main pulmonary tuberculosis cough spitting of blood; Jaundice; Damp-heat diarrhea; Dysentery; Conjunctival congestion and swelling pain; Eczema.
Herba Lanceae Tibeticae: base is former: be the herb of goatweed Fructus Lanceae tibeticae.Nature and flavor: sweet in the mouth; Bitter; Cold in nature.Function cures mainly: lung heat clearing; Evacuation of pus; Removing toxic substances; Detumescence.Main cough due to lung-heat; Lung abscess; Influenza; Dysentery; Laryngopharynx swelling and pain.
Large Ye Nansu: base is former: be the Herb of the large Ye Nansu of aroid.Nature and flavor: bitter in the mouth; Micro-sweet; Cool in nature.Function cures mainly: eliminating stasis to stop pain; Relaxing muscles and tendons and activating QI and blood in the collateral; Nourishing the lung to arrest cough.Main angina pectoris; Treating swelling and pain by traumatic injury; Fracture; Rheumatalgia; Numb limbs and tense tendons; Bronchitis; Pertussis.
Herba Chrysopogonis Aciculati: base is former: be herb or the root of grass Herba Commelinae Diffusae.Nature and flavor: micro-hardship; Sweet; Cool.Function cures mainly: clearing away heat-damp and promoting diuresis; Removing toxic substances.Main cold, fever; Stomachache is had loose bowels summer-heat hot urination; Acute toothache; Gold wound swells and ache; Venom.
The prescription scientific formulation curing toothache provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, therapeutic effect is good, and cure rate is high, effectively can prevent disease relapse;
2, this prescription meets Chinese medicine principle, has effect of stasis-dispelling and pain-killing, heat-clearing and toxic substances removing;
3, Chinese crude drug selected by the present invention, through clinical verification, drug effect safety, has no side effect.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1cure the prescription of toothache, be prepared from (every part of 10g) primarily of following bulk drugs: Flos Osmanthi Fragrantis 12 parts, Herba Chrysosplenii Macrophylli 10 parts, Daphne giraldii Nitsche 3 parts, Changuienia amoena Chien 8 parts, moth sets 9 parts, Herba Cyathulae Prostratae 7 parts, horse Auricled Hedyotis Herb 10 parts, Caulis Trachelospermi 8 parts, Herba Sheareriae 11 parts, Fructus anacardii 7 parts, Herba Stellariae Neglectae 9 parts, CIHUANQIN 6 parts, Herba Lanceae Tibeticae 8 parts, great Ye south Soviet Union 10 parts, Herba Chrysopogonis Aciculati 8 parts.The preparation method of the prescription soft extract of above-mentioned treatment toothache is:
(1) get Herba Chrysosplenii Macrophylli, Changuienia amoena Chien, Herba Cyathulae Prostratae, horse Auricled Hedyotis Herb, Herba Sheareriae, Herba Stellariae Neglectae and Herba Lanceae Tibeticae to clean, chopping, adds the soak by water of boiled crude drug quality 7 times, and big fire is heated to boiling, turns little fire and decocts 19 minutes, filter, collect filtrate;
(2) get moth tree and Fructus anacardii removing impurity, be placed in container, add refined honey water and do not have crude drug 1cm to infiltrate 5 minutes, be placed in by container in steamer, water proof heats 15 minutes, takes out, pulverizes;
(3) get Daphne giraldii Nitsche, CIHUANQIN, large Ye Nansu and Herba Chrysopogonis Aciculati and clean remove impurity, add water and soaking in rice vinegar 25 minutes, moderate heat boils and is sucked to vinegar liquid, and taking-up is dried, cutting;
(4) Flos Osmanthi Fragrantis and Caulis Trachelospermi are cleaned remove impurity, be cut into thread, be placed in hot pot, moderate heat stir-fries black to surperficial zoom, and drench into rice vinegar after closing fire, go out most Mars, moistening 3 minutes, takes out;
(5) pulverized by made to step (2) (3) (4) crude drug, be added in step (1) gained filtrate, heating is concentrated into clear paste, obtains soft extract.
embodiment 2cure the prescription of toothache, be prepared from (every part of 10g) primarily of following bulk drugs: Flos Osmanthi Fragrantis 18 parts, Herba Chrysosplenii Macrophylli 14 parts, Daphne giraldii Nitsche 6 parts, Changuienia amoena Chien 14 parts, moth sets 13 parts, Herba Cyathulae Prostratae 12 parts, horse Auricled Hedyotis Herb 13 parts, Caulis Trachelospermi 15 parts, Herba Sheareriae 14 parts, Fructus anacardii 13 parts, Herba Stellariae Neglectae 14 parts, CIHUANQIN 12 parts, Herba Lanceae Tibeticae 16 parts, great Ye south Soviet Union 16 parts, Herba Chrysopogonis Aciculati 13 parts.The preparation method of the prescription decoction of above-mentioned treatment toothache is:
(1) get Herba Chrysosplenii Macrophylli, Changuienia amoena Chien, Herba Cyathulae Prostratae, horse Auricled Hedyotis Herb, Herba Sheareriae, Herba Stellariae Neglectae and Herba Lanceae Tibeticae to clean, chopping, adds the soak by water of boiled crude drug quality 7.5 times, and big fire is heated to boiling, turns little fire and decocts 19 minutes, filter, collect filtrate;
(2) get moth tree and Fructus anacardii removing impurity, be placed in container, add refined honey water and do not have crude drug 1cm to infiltrate 5 minutes, be placed in by container in steamer, water proof heats 15 minutes, takes out, pulverizes;
(3) get Daphne giraldii Nitsche, CIHUANQIN, large Ye Nansu and Herba Chrysopogonis Aciculati and clean remove impurity, add water and soaking in rice vinegar 25 minutes, moderate heat boils and is sucked to vinegar liquid, and taking-up is dried, cutting;
(4) Flos Osmanthi Fragrantis and Caulis Trachelospermi are cleaned remove impurity, be cut into thread, be placed in hot pot, moderate heat stir-fries black to surperficial zoom, and drench into rice vinegar after closing fire, go out most Mars, moistening 3 minutes, takes out;
(5) pulverized by made to step (2) (3) (4) crude drug, be added in step (1) gained filtrate, heating is boiled to boiling, after filtration, collects filtrate, obtains decoction.
Model case: xxx, male, 32 years old.Main suit: toothache, red swelling of gingiva; , there is toothache symptom, gingival hemorrhage when eating in medical history: patient gets angry seriously recently, the pain increased to meet caloric stimulation, and on inspection, gingiva is rubescent, swell, and with vexed insomnia, the uncomfortable disease of degradation under appetite.
Take this example gained decoction, each 200-300ml, warmly to take, one day twice seven days is a course for the treatment of, and after patient takes a course for the treatment of, toothache symptom disappears substantially, and after continuing to take a course for the treatment of, uncomfortable disease is all eliminated, can normal diet, and patient fully recovers.
embodiment 3cure the prescription of toothache, be prepared from (every part of 10g) primarily of following bulk drugs: Flos Osmanthi Fragrantis 14 parts, Herba Chrysosplenii Macrophylli 11 parts, Daphne giraldii Nitsche 4 parts, Changuienia amoena Chien 10 parts, moth sets 10 parts, Herba Cyathulae Prostratae 9 parts, horse Auricled Hedyotis Herb 11 parts, Caulis Trachelospermi 10 parts, Herba Sheareriae 12 parts, Fructus anacardii 9 parts, Herba Stellariae Neglectae 11 parts, CIHUANQIN 8 parts, Herba Lanceae Tibeticae 10 parts, great Ye south Soviet Union 12 parts, Herba Chrysopogonis Aciculati 9 parts.The preparation method of the prescription powder of above-mentioned treatment toothache is:
(1) get Herba Chrysosplenii Macrophylli, Changuienia amoena Chien, Herba Cyathulae Prostratae, horse Auricled Hedyotis Herb, Herba Sheareriae, Herba Stellariae Neglectae and Herba Lanceae Tibeticae to clean, chopping, adds the soak by water of boiled crude drug quality 7 times, and big fire is heated to boiling, turns little fire and decocts 19 minutes, filter, collect filtrate;
(2) get moth tree and Fructus anacardii removing impurity, be placed in container, add refined honey water and do not have crude drug 1cm to infiltrate 5 minutes, be placed in by container in steamer, water proof heats 15 minutes, takes out, pulverizes;
(3) get Daphne giraldii Nitsche, CIHUANQIN, large Ye Nansu and Herba Chrysopogonis Aciculati and clean remove impurity, add water and soaking in rice vinegar 25 minutes, moderate heat boils and is sucked to vinegar liquid, and taking-up is dried, cutting;
(4) Flos Osmanthi Fragrantis and Caulis Trachelospermi are cleaned remove impurity, be cut into thread, be placed in hot pot, moderate heat stir-fries black to surperficial zoom, and drench into rice vinegar after closing fire, go out most Mars, moistening 3 minutes, takes out;
(5) spray drying step (1) gained filtrate, pulverized 150 mesh sieves by dry thing, obtained powder together with step (2) (3) (4) made crude drug.
Model case: xxx, women, 27 years old.Medical history: before one month, patient occurs toothache without obvious inducement, show effect in hurt like hell, and impact feed and sleep, once took tablet for alleviating pain, and still had recurrence, and on inspection, red swelling of gingiva, touches a tender spot obvious, be diagnosed as periodontitis.
Recommend to take this example gained powder, each 2-3g, warm boiled water through people, one day twice, within seven days, be a course for the treatment of, after patient takes a course for the treatment of, toothache remission, attack times declines, after adhering to taking two courses for the treatment of, toothache disappears substantially, other uncomfortable diseases, drug withdrawal is followed up a case by regular visits to after half a year, and the state of an illness does not recur.
embodiment 4cure the prescription of toothache, be prepared from (every part of 10g) primarily of following bulk drugs: Flos Osmanthi Fragrantis 16 parts, Herba Chrysosplenii Macrophylli 13 parts, Daphne giraldii Nitsche 5 parts, Changuienia amoena Chien 12 parts, moth sets 12 parts, Herba Cyathulae Prostratae 10 parts, horse Auricled Hedyotis Herb 12 parts, Caulis Trachelospermi 13 parts, Herba Sheareriae 13 parts, Fructus anacardii 11 parts, Herba Stellariae Neglectae 12 parts, CIHUANQIN 10 parts, Herba Lanceae Tibeticae 14 parts, great Ye south Soviet Union 14 parts, Herba Chrysopogonis Aciculati 12 parts.The preparation method of the prescription capsule of above-mentioned treatment toothache is:
(1) get Herba Chrysosplenii Macrophylli, Changuienia amoena Chien, Herba Cyathulae Prostratae, horse Auricled Hedyotis Herb, Herba Sheareriae, Herba Stellariae Neglectae and Herba Lanceae Tibeticae to clean, chopping, adds the soak by water of boiled crude drug quality 7 times, and big fire is heated to boiling, turns little fire and decocts 19 minutes, filter, collect filtrate;
(2) get moth tree and Fructus anacardii removing impurity, be placed in container, add refined honey water and do not have crude drug 1cm to infiltrate 5 minutes, be placed in by container in steamer, water proof heats 15 minutes, takes out, pulverizes;
(3) get Daphne giraldii Nitsche, CIHUANQIN, large Ye Nansu and Herba Chrysopogonis Aciculati and clean remove impurity, add water and soaking in rice vinegar 25 minutes, moderate heat boils and is sucked to vinegar liquid, and taking-up is dried, cutting;
(4) Flos Osmanthi Fragrantis and Caulis Trachelospermi are cleaned remove impurity, be cut into thread, be placed in hot pot, moderate heat stir-fries black to surperficial zoom, and drench into rice vinegar after closing fire, go out most Mars, moistening 3 minutes, takes out;
(5) pulverized by made to step (2) (3) (4) crude drug, be added in step (1) gained filtrate, heating is concentrated into thick paste, dries and pulverizes 75 mesh sieves, be packed in capsule, obtain capsule.
Model case: xxx, women, 11 years old.Medical history: patient has a sweet tooth, start in the recent period to occur toothache symptom, when eating harder food or meet caloric stimulation, pain is obviously aggravated, cannot normal diet, cries and screams and does not stop, through examination in hospital, be diagnosed as because of the toothache caused by dental caries.
Taking this example gained capsule, each 2-3 grain, warm boiled water, one day twice, seven days is a course for the treatment of, and after patient takes five days, toothache remission, substantially can normal diet, and after taking two courses for the treatment of, conditions of patients takes a turn for the better completely, without other uncomfortable diseases.
embodiment 5cure the prescription of toothache, be prepared from (every part of 10g) primarily of following bulk drugs: Flos Osmanthi Fragrantis 15 parts, Herba Chrysosplenii Macrophylli 12 parts, Daphne giraldii Nitsche 4.5 parts, Changuienia amoena Chien 11 parts, moth sets 11 parts, Herba Cyathulae Prostratae 9.5 parts, horse Auricled Hedyotis Herb 11.5 parts, Caulis Trachelospermi 11.5 parts, Herba Sheareriae 12.5 parts, Fructus anacardii 10 parts, Herba Stellariae Neglectae 11.5 parts, CIHUANQIN 9 parts, Herba Lanceae Tibeticae 12 parts, great Ye south Soviet Union 13 parts, Herba Chrysopogonis Aciculati 10.5 parts.The preparation method of the prescription soft extract of above-mentioned treatment toothache is:
(1) get Herba Chrysosplenii Macrophylli, Changuienia amoena Chien, Herba Cyathulae Prostratae, horse Auricled Hedyotis Herb, Herba Sheareriae, Herba Stellariae Neglectae and Herba Lanceae Tibeticae to clean, chopping, adds the soak by water of boiled crude drug quality 7 times, and big fire is heated to boiling, turns little fire and decocts 19 minutes, filter, collect filtrate;
(2) get moth tree and Fructus anacardii removing impurity, be placed in container, add refined honey water and do not have crude drug 1cm to infiltrate 5 minutes, be placed in by container in steamer, water proof heats 15 minutes, takes out, pulverizes;
(3) get Daphne giraldii Nitsche, CIHUANQIN, large Ye Nansu and Herba Chrysopogonis Aciculati and clean remove impurity, add water and soaking in rice vinegar 25 minutes, moderate heat boils and is sucked to vinegar liquid, and taking-up is dried, cutting;
(4) Flos Osmanthi Fragrantis and Caulis Trachelospermi are cleaned remove impurity, be cut into thread, be placed in hot pot, moderate heat stir-fries black to surperficial zoom, and drench into rice vinegar after closing fire, go out most Mars, moistening 3 minutes, takes out;
(5) pulverized by made to step (2) (3) (4) crude drug, be added in step (1) gained filtrate, heating is concentrated into clear paste, obtains soft extract.
test example 1gained of the present invention cures the clinical practice of the prescription (embodiment 5) of toothache:
Choose crowd: in June ,-2015 in March, 2014, according to medical case history, there is three hospital's screenings patient 283 example of toothache symptom, in age 11-62 year, 37.8 ± 3.2 years old mean age, the course of disease is 3 days-3 years, wherein male patient 139 example, female patient 144 example.
Before test, patient is divided into two groups at random, experimental group 160 example and matched group 123 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes products obtained therefrom of the present invention, each 6-8g, one day twice, warm boiled water, within seven days, is a course for the treatment of; Matched group takes other conventional medicines (Fu Fang Ya Tong Ding, Yazhoukang, ibuprofen etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: toothache transference cure, and chance caloric stimulation is without exception; (2) effective: toothache transference cure, meet caloric stimulation or still have swelling and pain sense when chewing hard object; (3) effective: toothache symptom takes a turn for the better, meet caloric stimulation and when chewing hard object, pain increases the weight of; (4) invalid: before and after treatment, symptom is not improved or increases the weight of.Total effective rate=cure rate+obvious effective rate
Clinical effectiveness: after the taking medicine of two courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
As shown in Table 1, the healing patient of experimental group is 113 examples, and effective patient is 34 examples, and effective patient is 11 examples, total effective rate is 91.9%, and the patient that matched group is cured is 63 examples, effective patient is 28 examples, and effective patient is 14 examples, total effective rate 74.0%, be starkly lower than the therapeutic effect of experimental group, illustrate that products obtained therefrom of the present invention is evident in efficacy, cure rate is high.
The Chinese medicine used in the present invention, Flos Osmanthi Fragrantis resolving phlegm and dissipating blood stasis, Herba Chrysosplenii Macrophylli, Herba Stellariae Neglectae heat-clearing and toxic substances removing, Daphne giraldii Nitsche stasis-dispelling and pain-killing, Changuienia amoena Chien clearing away heat and cooling blood, moth tree antiinflammatory antitussive, Herba Cyathulae Prostratae promoting blood circulation to remove blood stasis, horse Auricled Hedyotis Herb, Herba Sheareriae inducing diuresis to remove edema, Caulis Trachelospermi dispelling wind and removing obstruction in the collateral, Fructus anacardii nourishing the lung to arrest cough, CIHUANQIN heat clearing and damp drying, Herba Lanceae Tibeticae removing toxic substances and promoting subsidence of swelling, large Ye Nansu eliminating stasis to stop pain, Herba Chrysopogonis Aciculati clearing away heat-damp and promoting diuresis, multiple medical material synergism, plays effect of stasis-dispelling and pain-killing, heat-clearing and toxic substances removing altogether.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. cure the prescription of toothache, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Flos Osmanthi Fragrantis 12-18; Herba Chrysosplenii Macrophylli 10-14; Daphne giraldii Nitsche 3-6; Changuienia amoena Chien 8-14; Moth tree 9-13; Herba Cyathulae Prostratae 7-12; Horse Auricled Hedyotis Herb 10-13; Caulis Trachelospermi 8-15; Herba Sheareriae 11-14; Fructus anacardii 7-13; Herba Stellariae Neglectae 9-14; CIHUANQIN 6-12; Herba Lanceae Tibeticae 8-16; great Ye south Soviet Union 10-16; Herba Chrysopogonis Aciculati 8-13.
2. prescription of curing toothache as claimed in claim 1, is characterized in that, Flos Osmanthi Fragrantis 14-16; Herba Chrysosplenii Macrophylli 11-13; Daphne giraldii Nitsche 4-5; Changuienia amoena Chien 10-12; Moth tree 10-12; Herba Cyathulae Prostratae 9-10; Horse Auricled Hedyotis Herb 11-12; Caulis Trachelospermi 10-13; Herba Sheareriae 12-13; Fructus anacardii 9-11; Herba Stellariae Neglectae 11-12; CIHUANQIN 8-10; Herba Lanceae Tibeticae 10-14; great Ye south Soviet Union 12-14; Herba Chrysopogonis Aciculati 9-12(is preferably: Flos Osmanthi Fragrantis 15; Herba Chrysosplenii Macrophylli 12; Daphne giraldii Nitsche 4.5; Changuienia amoena Chien 11; Moth tree 11; Herba Cyathulae Prostratae 9.5; Horse Auricled Hedyotis Herb 11.5; Caulis Trachelospermi 11.5; Herba Sheareriae 12.5; Fructus anacardii 10; Herba Stellariae Neglectae 11.5; CIHUANQIN 9; Herba Lanceae Tibeticae 12; great Ye south Soviet Union 13; Herba Chrysopogonis Aciculati 10.5).
3. the prescription of the treatment toothache as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable soft extract, its preparation method is:
(1) get Herba Chrysosplenii Macrophylli, Changuienia amoena Chien, Herba Cyathulae Prostratae, horse Auricled Hedyotis Herb, Herba Sheareriae, Herba Stellariae Neglectae and Herba Lanceae Tibeticae to clean, chopping, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times) to decoct, big fire is heated to boiling, turns little fire and decocts 12-26 minute (preferably: turn little fire and decoct 16-22 minute; Be more preferably: turn little fire and decoct 19 minutes), filter, collect filtrate;
(2) get moth tree and Fructus anacardii removing impurity, be placed in container, add refined honey water infiltration 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(3) get Daphne giraldii Nitsche, CIHUANQIN, large Ye Nansu and Herba Chrysopogonis Aciculati and clean remove impurity, add water and soaking in rice vinegar 20-30 minute (preferred: to soak 22-28 minute; Be more preferably: soak 25 minutes), moderate heat boils and is sucked to vinegar liquid, and taking-up is dried, cutting;
(4) Flos Osmanthi Fragrantis and Caulis Trachelospermi are cleaned remove impurity, be cut into thread, be placed in hot pot, moderate heat stir-fries black to surperficial zoom, and drench into rice vinegar after closing fire, go out most Mars, moistening 3 minutes, takes out;
(5) pulverized by made to step (2) (3) (4) crude drug, be added in step (1) gained filtrate, heating is concentrated into clear paste, obtains soft extract.
4. the preparation method curing the prescription soft extract of toothache as claimed in claim 3, it is characterized in that, the amount that step (2) adds refined honey water was as the criterion there not to be crude drug 1cm.
5. the prescription of the treatment toothache as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Herba Chrysosplenii Macrophylli, Changuienia amoena Chien, Herba Cyathulae Prostratae, horse Auricled Hedyotis Herb, Herba Sheareriae, Herba Stellariae Neglectae and Herba Lanceae Tibeticae to clean, shred, decoct with water, big fire is heated to boiling, turns little fire and decocts 12-26 minute (preferably: turn little fire and decoct 16-22 minute; Be more preferably: turn little fire and decoct 19 minutes), filter, collect filtrate;
(2) get moth tree and Fructus anacardii removing impurity, be placed in container, add refined honey water and do not have crude drug 1cm to infiltrate 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(3) get Daphne giraldii Nitsche, CIHUANQIN, large Ye Nansu and Herba Chrysopogonis Aciculati and clean remove impurity, add water and soaking in rice vinegar 20-30 minute (preferred: to soak 22-28 minute; Be more preferably: soak 25 minutes), moderate heat boils and is sucked to vinegar liquid, and taking-up is dried, cutting;
(4) Flos Osmanthi Fragrantis and Caulis Trachelospermi are cleaned remove impurity, be cut into thread, be placed in hot pot, moderate heat stir-fries black to surperficial zoom, and drench into rice vinegar after closing fire, go out most Mars, moistening 3 minutes, takes out;
(5) pulverized by made to step (2) (3) (4) crude drug, be added in step (1) gained filtrate, heating is boiled to boiling, after filtration, collects filtrate, obtains decoction.
6. the preparation method curing the prescription decoction of toothache as claimed in claim 5, is characterized in that, the 6-9 that step (1) amount of water is boiled crude drug quality is doubly (preferred: the 7-8 that amount of water is boiled crude drug quality doubly; Be more preferably: amount of water is 7.5 times of boiled crude drug quality).
7. the prescription of the treatment toothache as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Herba Chrysosplenii Macrophylli, Changuienia amoena Chien, Herba Cyathulae Prostratae, horse Auricled Hedyotis Herb, Herba Sheareriae, Herba Stellariae Neglectae and Herba Lanceae Tibeticae to clean, chopping, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times) to decoct, big fire is heated to boiling, turns little fire and decocts 12-26 minute (preferably: turn little fire and decoct 16-22 minute; Be more preferably: turn little fire and decoct 19 minutes), filter, collect filtrate;
(2) get moth tree and Fructus anacardii removing impurity, be placed in container, add refined honey water and do not have crude drug 1cm to infiltrate 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(3) get Daphne giraldii Nitsche, CIHUANQIN, large Ye Nansu and Herba Chrysopogonis Aciculati and clean remove impurity, add water and soaking in rice vinegar 20-30 minute (preferred: to soak 22-28 minute; Be more preferably: soak 25 minutes), moderate heat boils and is sucked to vinegar liquid, and taking-up is dried, cutting;
(4) Flos Osmanthi Fragrantis and Caulis Trachelospermi are cleaned remove impurity, be cut into thread, be placed in hot pot, moderate heat stir-fries black to surperficial zoom, and drench into rice vinegar after closing fire, go out most Mars, moistening 3 minutes, takes out;
(5) spray drying step (1) gained filtrate, pulverizes and sieves dry thing, obtains powder together with step (2) (3) (4) made crude drug.
8. the preparation method curing the prescription powder of toothache as claimed in claim 7, is characterized in that, it is (preferred: to pulverize 140-160 mesh sieve that step (5) pulverized 120-180 mesh sieve; Be more preferably: pulverized 150 mesh sieves).
9. the prescription of the treatment toothache as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get Herba Chrysosplenii Macrophylli, Changuienia amoena Chien, Herba Cyathulae Prostratae, horse Auricled Hedyotis Herb, Herba Sheareriae, Herba Stellariae Neglectae and Herba Lanceae Tibeticae to clean, chopping, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times) to decoct, big fire is heated to boiling, turns little fire and decocts 12-26 minute (preferably: turn little fire and decoct 16-22 minute; Be more preferably: turn little fire and decoct 19 minutes), filter, collect filtrate;
(2) get moth tree and Fructus anacardii removing impurity, be placed in container, add refined honey water and do not have crude drug 1cm to infiltrate 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(3) get Daphne giraldii Nitsche, CIHUANQIN, large Ye Nansu and Herba Chrysopogonis Aciculati and clean remove impurity, add water and soaking in rice vinegar 20-30 minute (preferred: to soak 22-28 minute; Be more preferably: soak 25 minutes), moderate heat boils and is sucked to vinegar liquid, and taking-up is dried, cutting;
(4) Flos Osmanthi Fragrantis and Caulis Trachelospermi are cleaned remove impurity, be cut into thread, be placed in hot pot, moderate heat stir-fries black to surperficial zoom, and drench into rice vinegar after closing fire, go out most Mars, moistening 3 minutes, takes out;
(5) pulverized by made to step (2) (3) (4) crude drug, be added in step (1) gained filtrate, heating is concentrated into thick paste, and oven dry pulverizes and sieves, and is packed in capsule, obtains capsule.
10. the preparation method curing the prescription capsule of toothache as claimed in claim 9, is characterized in that, it is (preferred: to pulverize 60-90 mesh sieve that step (5) pulverized 40-110 mesh sieve; Be more preferably: pulverized 75 mesh sieves).
CN201510531507.4A 2015-08-27 2015-08-27 Prescription for treating toothache and preparation method thereof Pending CN105031363A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1243730A (en) * 1998-08-04 2000-02-09 特古斯 Special medicine 'E'erdemusan' for treating toothache
CN104524170A (en) * 2014-12-26 2015-04-22 丁鸿磊 Traditional Chinese medicine for treating wind-fire toothache and preparation method thereof
CN104645062A (en) * 2015-03-23 2015-05-27 饶烨 Traditional Chinese medicine composition for treating toothache and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1243730A (en) * 1998-08-04 2000-02-09 特古斯 Special medicine 'E'erdemusan' for treating toothache
CN104524170A (en) * 2014-12-26 2015-04-22 丁鸿磊 Traditional Chinese medicine for treating wind-fire toothache and preparation method thereof
CN104645062A (en) * 2015-03-23 2015-05-27 饶烨 Traditional Chinese medicine composition for treating toothache and preparation method thereof

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