CN104997951A - Traditional Chinese medicine plaster treating lumbar disc herniation and manufacturing method - Google Patents

Traditional Chinese medicine plaster treating lumbar disc herniation and manufacturing method Download PDF

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CN104997951A
CN104997951A CN201510483034.5A CN201510483034A CN104997951A CN 104997951 A CN104997951 A CN 104997951A CN 201510483034 A CN201510483034 A CN 201510483034A CN 104997951 A CN104997951 A CN 104997951A
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herba
parts
radix
chinese medicine
prolapse
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陈欣
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陈欣
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Abstract

The invention discloses a traditional Chinese medicine plaster treating lumbar disc herniation. The plaster comprises, by mass, 8-13 parts of cortex erythrinae, 10-14 parts of latouchea fokiensis, 6-15 parts of semen strychni, 9-13 parts of youth-and-old-age, 7-12 parts of evergreen mucuna roots and leaves, 6-10 parts of passion flowers, 11-16 parts of fructus forsythiae, 9-16 parts of common achyranthes herbs, 8-12 parts of lycopus lucidus, 6-14 parts of angiopteris fokiensis hieron, 9-15 parts of pyrola, 7-14 parts of cantonese ampelopsis, 8-15 parts of saussurea cordifolia and 10-13 parts of siberian walking fern. The traditional Chinese medicine plaster is prepared through clinical practice summarization of many years, has the advantages of promoting blood circulation and stopping pain and dispelling wind and removing obstruction in the meridians, and is remarkable in treatment effect.

Description

A kind of Chinese medicine patch and method for making for the treatment of prolapse of lumbar intervertebral disc
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine patch and method for making for the treatment of prolapse of lumbar intervertebral disc.
Background technology
Prolapse of lumbar intervertebral disc is one of comparatively common clinically lumbar disease, is the commonly encountered diseases of orthopedics department, frequently-occurring disease.Lumbar intervertebral disc is present between each vertebral body of lumbar vertebra, is the ingredient of joint of lumbar vertebra, and play a part to support, connect and buffering to lumbar vertebra, its shape resembles an abacus bead flattened, and is made up of vertebral pulp, cartilaginous lamina, fibrous ring three part.Convex or fracture after causing fibrous ring due to the reason such as wound, regression, vertebral pulp is deviate from, and is just called prolapse of lumbar intervertebral disc.Because spinal cord is by the rear process of intercalated disc, when outstanding intercalated disc compressing spinal nerves or cauda equina nerve cause lumbago and skelalgia or gatism, even cause paralysis time, be just called prolapse of lumbar intervertebral disc.The most common symptom of patients with lumbar disc herniation is pain, can show as lumbago and backache, sciatica, typical sciatica show as by rear side of buttocks, thigh, little leg outer side is to the radiating pain on heel or instep.
Publication No. CN 103405568 A(application number 201310387514.2) Chinese patent literature disclose a kind of Chinese medicine for the treatment of prolapse of lumbar intervertebral disc, it is made up of by weight the ingredients in following prescription: Radix Angelicae Sinensis 10-14, Radix Paeoniae Alba 18-22, Rhizoma Chuanxiong 18-22, Radix Achyranthis Bidentatae 11-13, Flos Carthami 11-13, Radix Notoginseng 10-14, Scorpio 4-10, Solenognathus 8-12, Caulis Sargentodoxae 11-15, Ramulus Cinnamomi 14-16, fragrant 11-13, Rhizoma Cibotii 11-15, hair Rhizoma Zingiberis Recens 11-13, Rhizoma Et Radix Notopterygii 11-13, Herba Taxilli 14-16, Rhizoma Atractylodis 11-13, Radix Rehmanniae 19-21, Cortex Eucommiae 11-13, Radix Gentianae Macrophyllae 11-13, Herba Ephedrae 7-9, Herba Lycopodii 14-20.Publication No. CN 104000909 A(application number 201410227184.5) Chinese patent literature disclose a kind of Chinese medicine for the treatment of prolapse of lumbar intervertebral disc.The Chinese medicine of this treatment prolapse of lumbar intervertebral disc, with Radix Angelicae Sinensis, Caulis Spatholobi, Radix Polygoni Multiflori Preparata, Radix Paeoniae Rubra, Radix Dipsaci, Herba Taxilli, prepared RADIX CLEMATIDIS with yellow rice wine, Herba Lycopodii, Herba speranskiae tuberculatae, Radix Notoginseng, Rhizoma Chuanxiong, eupolyphaga, Lignum Pini Nodi, Flos Carthami, Fructus Psoraleae, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae (parched), Pericarpium Citri Reticulatae, the Radix Aucklandiae and Semen Phaseoli for raw material, be mixed according to certain weight proportion.Publication No. CN 103893653 A(application number 201410130196.6) Chinese patent literature disclose a kind of Chinese medicine for the treatment of prolapse of lumbar intervertebral disc, it is made up by weight of following medicine: Radix Astragali 2 parts; Radix codonopsis pilosulae (Radix Codonopsis) 1 part; At least one 1 part in Radix Angelicae Sinensis and Rhizoma Chuanxiong; The Rhizoma Atractylodis Macrocephalae 1 part; The Radix Paeoniae Alba 1 part; Rhizoma Dioscoreae 1 part; 3 parts, Radix Rehmanniae Preparata; Blood collects 2 parts; Ramulus Cinnamomi 1 part; Fructus Chaenomelis 1 part; Radix Achyranthis Bidentatae 1 part; Maple collects 1 part in sea; 1 part, Semen Persicae; Radix Polygoni Multiflori Preparata 2 parts; Semen Cuscutae 2 parts; Fructus Rubi 2 parts; Psoralen 2 parts; Fructus Alpiniae Oxyphyllae 2 parts; Rhizoma Cibotii 2 parts; Radix Dipsaci 2 parts; Fructus Lycii 1 part; Fructus Corni 1 part; Pericarpium Citri Reticulatae 1 part; The Rhizoma Pinelliae 1 part; Cortex erythrinae 1 part; Rhizoma Atractylodis 2 parts; Pyritum 2 parts; Herba sambuci chinensis 2 parts; Eupolyphaga seu steleophaga 1 part; Radix Notoginseng 1 part; Radix Aconiti 1 part; Radix Aconiti Kusnezoffii 1 part; Olibanum 1 part; Myrrha 1 part; Rhizoma Et Radix Notopterygii 1 part; Radix Angelicae Pubescentis 1 part; Herba Taxilli 1 part; Herba Aristolochiae Mollissimae 1 part; Cortex schizophragmatis integrifolii radicis 1 part; Rhizoma Homalomenae 1 part.
Being used for the treatment of the medicine of prolapse of lumbar intervertebral disc at present more is based on relief of symptoms, cures the symptoms, not the disease, and brings larger misery to patient, expenses of surgical treatment is high, injury is large, is not suitable for all patients, therefore needs the Chinese medicine formula providing a kind of good effect, no pain.
Summary of the invention
For the problem of prior art, the object of this invention is to provide the wide treatment prolapse of lumbar intervertebral disc Chinese medicine patch of a kind of Be very effective, the use safety suitability and method for making.
Technical scheme of the present invention is:
Treat a Chinese medicine patch for prolapse of lumbar intervertebral disc, be prepared from primarily of following bulk drugs, be mass parts: Cortex erythrinae 8-13; Radix limonii sinensis 10-14; Semen Strychni 6-15; Youth-and-old-age 9-13; Radix Seu Caulis Mucunae Sempervirentis 7-12; Herba Passiflorae Caeruleae 6-10; Fructus Forsythiae 11-16; Radix achyranthis asperae (Herba Achyranthis Asperae) 9-16; Herba Lycopi 8-12; Rhizoma Angiopteridis Fokiensis 6-14; Herba Pyrolae 9-15; Radix Ampelopsis Cantoniensis 7-14; Saussurea cordifolia 8-15; Herba Camptosori Sibirici 10-13.
Preferred version is, Cortex erythrinae 9-12; Radix limonii sinensis 11-13; Semen Strychni 8-13; Youth-and-old-age 10-12; Radix Seu Caulis Mucunae Sempervirentis 9-10; Herba Passiflorae Caeruleae 7-9; Fructus Forsythiae 12-15; Radix achyranthis asperae (Herba Achyranthis Asperae) 11-14; Herba Lycopi 9-11; Rhizoma Angiopteridis Fokiensis 8-12; Herba Pyrolae 11-13; Radix Ampelopsis Cantoniensis 9-12; Saussurea cordifolia 10-13; Herba Camptosori Sibirici 11-12.
More preferably, Cortex erythrinae 10.5; Radix limonii sinensis 12; Semen Strychni 10.5; Youth-and-old-age 11; Radix Seu Caulis Mucunae Sempervirentis 9.5; Herba Passiflorae Caeruleae 8; Fructus Forsythiae 13.5; Radix achyranthis asperae (Herba Achyranthis Asperae) 12.5; Herba Lycopi 10; Rhizoma Angiopteridis Fokiensis 10; Herba Pyrolae 12; Radix Ampelopsis Cantoniensis 10.5; Saussurea cordifolia 11.5; Herba Camptosori Sibirici 11.5.
Described a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc, step is as follows:
(1) get Semen Strychni and clean remove impurity, be placed in marmite, it is (preferred: to boil 28-32 minute to add rice washing decocting in water 25-35 minute; Be more preferably: boil 30 minutes), take out together with Fructus Forsythiae, be placed in frying pan, intense fire stir-fries to surperficial zoom, pulverizes, and drench into crystal sugar water, slow fire dries, and takes out;
(2) get Cortex erythrinae, Radix Seu Caulis Mucunae Sempervirentis, Rhizoma Angiopteridis Fokiensis, Radix Ampelopsis Cantoniensis and Saussurea cordifolia and pick up clean impurity, clear water is cleaned, and adds ginger slice, is placed in boiling water together and did not have medical material 2cm, airtight immersion, takes out and cuts into slices or section, and slow fire is dried, and pulverizes and sieves;
(3) by clean to Radix limonii sinensis, youth-and-old-age, Herba Passiflorae Caeruleae, Radix achyranthis asperae (Herba Achyranthis Asperae), Herba Lycopi, Herba Pyrolae and Herba Camptosori Sibirici wash quickly, be placed in marmite, decoct with water, big fire is heated to boiling, turn little fire to decoct, after filtration, collect filtrate, filtering residue adds boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) and again decocts 20 minutes, filters merging twice gained filtrate;
(4) step (1) (2) made crude drug is joined in step (3) gained filtrate, is evaporated to thick paste, add adjuvant mixing, make medicine carrying mastic, then through coating, cutting, leave standstill, packaging etc., make Chinese medicine patch.
Described a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc, step (1) amount of drenching into crystal sugar water be the 0.3-0.6 of crude drug quality doubly (preferred: the amount of drenching into crystal sugar water be the 0.4-0.5 of crude drug quality doubly; Be more preferably: the amount of drenching into crystal sugar water is 0.45 times of crude drug quality).
Described a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc, step (2) airtight immersion 22-36 minute is (preferred: airtight immersion 26-32 minute; Be more preferably: airtight immersion 29 minutes).
Described a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc, it is (preferred: to pulverize 120-140 mesh sieve that step (2) pulverized 100-160 mesh sieve; Be more preferably: pulverized 130 mesh sieves).
Described a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc, the 6-8 that step (3) amount of water is boiled crude drug quality is doubly (preferred: the 6.5-7.5 that amount of water is boiled crude drug quality is doubly; Be more preferably: amount of water is 7 times of boiled crude drug quality).
Described a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc, step (3) turns little fire and decocts 24-38 minute (preferably: turn little fire and decoct 28-34 minute; Be more preferably: turn little fire and decoct 31 minutes).
Described a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc, it is (preferred: to be evaporated to the thick paste that relative density is 1.18-1.22 that step (4) is evaporated to the thick paste (75 DEG C) that relative density is 1.14-1.26; Be more preferably: be evaporated to the thick paste that relative density is 1.20).
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Cortex erythrinae: base is former: be the dried bark of leguminous plant erythrina indica.Chemical analysis: bark is containing erythraline, aminoacid and organic acid.Nature and flavor: toil are flat.Gui Jing: enter liver, spleen channel.Function cures mainly: wind-damp dispelling, the meridian dredging, parasite killing.Dispelling the wind and dampness pathogens arthralgia pain, dysentery, toothache, scabies.
Radix limonii sinensis: base is former: be the herb of gentianaceae plant Radix limonii sinensis.Nature and flavor: bitter; Pungent; Cold in nature.Gui Jing: lung; Liver; Large intestine channel.Function cures mainly: blood circulation promoting and blood stasis dispelling; Clearing and antitussive.Blood stasis mass in the abdomen in main abdomen; Epersalgia cough.
Semen Strychni: base is former: be the mature seed of loganiaceae plant Semen Strychni.Pluck during fruit maturation, removing sarcocarp, takes out seed, dries.Chemical analysis: containing brucine, strychnine, α-and β-Ke Lubo, vomicine, novacine, icajine, loganin etc.Nature and flavor: bitter, cold, poisonous.Function cures mainly: loose heat in blood, detumescence, pain relieving.Control throat arthralgia pain, swollen ulcer drug, migratory arthralgia pain, fracture.And control facial paralysis, myasthenia gravis.Removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.For rheumatoid arthritis stubborn, paralysis and numbness, injury from falling down, ulcer sore pain.
Youth-and-old-age: base is former: be the herb of feverfew Herba Zinnia elegansae.Nature and flavor: bitter in the mouth; Pungent; Cool in nature.Function cures mainly: heat clearing away; Dampness removing; Removing toxic substances.Main hygropyretic dysentery; Stranguria; Acute mastitis; Furuncle and phyma.
Radix Seu Caulis Mucunae Sempervirentis: base is former: be the stem of the evergreen mucuna of leguminous plant.Nature and flavor: bitter; Micro-hardship; Warm in nature.Gui Jing: liver; Stomach warp.Function cures mainly: promoting blood flow to regulate menstruation; To enrich blood relaxing muscles and tendons.Main have through uncomfortable; Dysmenorrhea; Amenorrhea; Puerperal blood deficiency; Anemia; Rheumatic arthralgia; Numb limbs and tense tendons; Traumatic injury.
Herba Passiflorae Caeruleae: base is former: be the herb of Passifloraceae plant Herba Passiflorae Caeruleae.Nature and flavor: bitter in the mouth; Warm in nature.Function cures mainly: except wind; Dehumidifying; Invigorate blood circulation; Pain relieving.Main headache due to common cold; Nasal obstruction watery nasal discharge; Rheumatic arthritis; Dysmenorrhea; Neuralgia; Lose eye; Dysentery; Fracture.
Fructus Forsythiae: nature and flavor with return through: bitter, be slightly cold.Return lung, the heart, small intestine meridian; There is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, effect of dispelling wind and heat pathogens; For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warm people battalion, high hot excessive thirst, coma sends out speckle, the puckery pain of pyretic stranguria.
Radix achyranthis asperae (Herba Achyranthis Asperae): base is former: be the herb of amaranthaceous plant coarse wool Radix Achyranthis Bidentatae.Nature and flavor: bitter; Acid; Cold nature.Gui Jing: liver; Lung; Urinary bladder channel.Function cures mainly: blood circulation promoting and blood stasis dispelling; Inducing diuresis for treating stranguria syndrome; Clearing away heat and expelling pathogen in the exterior.Main warp closes; Dysmenorrhea; Menoxenia; Traumatic injury; Rheumatic arthritis; Gonorrhea; Edema; Damp-heat vaginal discharge, fever caused by exogenous pathogens; Malaria; Pharyngalgia; Furuncle carbuncle.
Herba Lycopi: nature and flavor with return through: bitter, pungent, tepor.Return liver, spleen channel.There is promoting blood flow to regulate menstruation, blood stasis dispelling eliminating carbuncle, effect of inducing diuresis to remove edema.For menoxenia, amenorrhea, dysmenorrhea, postnatal blood stasis is suffered from abdominal pain, sore and toxic, edema ascites.
Rhizoma Angiopteridis Fokiensis: base is former: be the rhizome of Angiopteridaceae plant Fujian kwan-yin seat lotus.Nature and flavor: bitter; Cold; Cool.Gui Jing: the heart; Lung meridian.Function cures mainly: clearing away heat and cooling blood; Hemostasis by removing blood stasis; Analgesia is calmed the nerves.Main mumps; Carbuncle sore tumefacting virus; Venom; Treating swelling and pain by traumatic injury; Traumatic hemorrhage; Metrorrhagia; Acute mastitis; Rheumatic arthralgia; Puerperal abdonimal pain; Vexed insomnia.
Herba Pyrolae: base is former: be the herb of Pyrolaceae plant traditional embankment, Herba pyrolae japonicae, pyrola japonicaKlenze ex Alef, Herba Pyrolae incarnatae.Nature and flavor: sweet; Bitter; Warm in nature.Gui Jing: liver; Kidney channel.Function cures mainly: the kidney invigorating bone strengthening; Expelling wind and removing dampness; Cough-relieving; Hemostasis.Main lumbago due to renal deficiency; Rheumatic arthralgia; Muscles and bones flaccidity is soft; New chronic cough is coughed; Spit blood; Epistaxis; Metrorrhagia; Traumatic hemorrhage.
Radix Ampelopsis Cantoniensis: base is former: be root or the Herb of vitaceae Caulis seu folium ampelopsis brevipedunculatae in Guangdong.Nature and flavor: pungent; Bitter; Cool.Gui Jing: the heart; Spleen channel.Function cures mainly: removing dampness of dispeling the wind; Heat-clearing and toxic substances removing.Main summer catches a cold; Rheumatic arthralgia; Swollen ulcer drug; Eczema eczema.
Saussurea cordifolia: base is former: be the root of feverfew Saussurea cordifolia.Nature and flavor: acrid in the mouth; Warm in nature.Function cures mainly: dispel the wind; Cold expelling; Pain relieving.Main air pain of dampness syndrome; Traumatic injury.
Herba Camptosori Sibirici: base is former: be the herb of Aspleniaceae plant walking fern.Nature and flavor: light; Flat.Gui Jing: heart channel.Function cures mainly: blood circulation promoting and blood stasis dispelling; Hemostasis; Removing toxic substances.Main thromboangiitis obliterans; Hemiplegia; Metrorrhagia; Traumatic hemorrhage; Neurodermatitis; Ulcer of the lower limb.
One provided by the invention treats prolapse of lumbar intervertebral disc Chinese medicine patch scientific formulation, and preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, therapeutic effect is good, and cure rate is high, effectively can effect a radical cure old complaint;
2, this formula is summed up through clinical practice for many years and is formed, and has effect of promoting blood circulation and stopping pain, dispelling wind and removing obstruction in the collateral;
3, products obtained therefrom of the present invention, safety has no side effect, drug effect direct effect affected part, and easy to carry.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1treat a Chinese medicine patch for prolapse of lumbar intervertebral disc, be prepared from (every part of 10g) primarily of following bulk drugs: Cortex erythrinae 8 parts, Radix limonii sinensis 10 parts, Semen Strychni 6 parts, youth-and-old-age 9 parts, Radix Seu Caulis Mucunae Sempervirentis 7 parts, Herba Passiflorae Caeruleae 6 parts, Fructus Forsythiae 11 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 9 parts, Herba Lycopi 8 parts, Rhizoma Angiopteridis Fokiensis 6 parts, Herba Pyrolae 9 parts, Radix Ampelopsis Cantoniensis 7 parts, Saussurea cordifolia 8 parts, Herba Camptosori Sibirici 10 parts.Above-mentioned a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc is:
(1) get Semen Strychni and clean remove impurity, be placed in marmite, add rice washing decocting in water 25 minutes, take out together with Fructus Forsythiae, be placed in frying pan, intense fire stir-fries to surperficial zoom, pulverizes, and drench the crystal sugar water into crude drug quality 0.3 times, slow fire dries, and takes out;
(2) get Cortex erythrinae, Radix Seu Caulis Mucunae Sempervirentis, Rhizoma Angiopteridis Fokiensis, Radix Ampelopsis Cantoniensis and Saussurea cordifolia and pick up clean impurity, clear water is cleaned, and adds ginger slice, is placed in boiling water together and did not have medical material 2cm, airtight immersion 22 minutes, takes out and cuts into slices or section, and slow fire is dried, and pulverizes 100 mesh sieves;
(3) by clean to Radix limonii sinensis, youth-and-old-age, Herba Passiflorae Caeruleae, Radix achyranthis asperae (Herba Achyranthis Asperae), Herba Lycopi, Herba Pyrolae and Herba Camptosori Sibirici wash quickly, be placed in marmite, add the soak by water of boiled crude drug quality 6 times, big fire is heated to boiling, turn little fire to decoct 24 minutes, after filtration, collect filtrate, the water that filtering residue adds boiled crude drug quality 5 times decocts 20 minutes again, filters merging twice gained filtrate;
(4) step (1) (2) made crude drug is joined in step (3) gained filtrate, be evaporated to relative density be 1.14 thick paste (75 DEG C), add adjuvant mixing, make medicine carrying mastic, again through coating, cutting, leave standstill, packaging etc., make Chinese medicine patch.
embodiment 2treat a Chinese medicine patch for prolapse of lumbar intervertebral disc, be prepared from (every part of 10g) primarily of following bulk drugs: Cortex erythrinae 13 parts, Radix limonii sinensis 14 parts, Semen Strychni 15 parts, youth-and-old-age 13 parts, Radix Seu Caulis Mucunae Sempervirentis 12 parts, Herba Passiflorae Caeruleae 10 parts, Fructus Forsythiae 16 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 16 parts, Herba Lycopi 12 parts, Rhizoma Angiopteridis Fokiensis 14 parts, Herba Pyrolae 15 parts, Radix Ampelopsis Cantoniensis 14 parts, Saussurea cordifolia 15 parts, Herba Camptosori Sibirici 13 parts.Above-mentioned a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc is:
(1) get Semen Strychni and clean remove impurity, be placed in marmite, add rice washing decocting in water 35 minutes, take out together with Fructus Forsythiae, be placed in frying pan, intense fire stir-fries to surperficial zoom, pulverizes, and drench the crystal sugar water into crude drug quality 0.6 times, slow fire dries, and takes out;
(2) get Cortex erythrinae, Radix Seu Caulis Mucunae Sempervirentis, Rhizoma Angiopteridis Fokiensis, Radix Ampelopsis Cantoniensis and Saussurea cordifolia and pick up clean impurity, clear water is cleaned, and adds ginger slice, is placed in boiling water together and did not have medical material 2cm, airtight immersion 36 minutes, takes out and cuts into slices or section, and slow fire is dried, and pulverizes 160 mesh sieves;
(3) by clean to Radix limonii sinensis, youth-and-old-age, Herba Passiflorae Caeruleae, Radix achyranthis asperae (Herba Achyranthis Asperae), Herba Lycopi, Herba Pyrolae and Herba Camptosori Sibirici wash quickly, be placed in marmite, add the soak by water of boiled crude drug quality 8 times, big fire is heated to boiling, turn little fire to decoct 38 minutes, after filtration, collect filtrate, the water that filtering residue adds boiled crude drug quality 7 times decocts 20 minutes again, filters merging twice gained filtrate;
(4) step (1) (2) made crude drug is joined in step (3) gained filtrate, be evaporated to relative density be 1.26 thick paste (75 DEG C), add adjuvant mixing, make medicine carrying mastic, again through coating, cutting, leave standstill, packaging etc., make Chinese medicine patch.
Model case: xxx, male, 39 years old.Main suit: suffer from prolapse of lumbar intervertebral disc 2 years, period once did massage, and symptom makes moderate progress, and overworked in the recent period, and the state of an illness starts to increase the weight of, lumbago and skelalgia, and with limitation of activity, sleep quality is poor, and left side health is numb, comparatively difficulty of leaving the bed.
Use this example gained Chinese medicine patch, be affixed on affected part, within one day, change once; within 15 days, be a course for the treatment of, after patient uses a course for the treatment of, pain alleviates to some extent; can light activity, after adhering to three courses for the treatment of of use, the state of an illness is obviously improved; the mental status takes a turn for the better, can normal activity, without lumbago and skelalgia; after consolidating a course for the treatment of; patient fully recovers, and follow up a case by regular visits in half a year, the state of an illness does not recur again.
embodiment 3treat a Chinese medicine patch for prolapse of lumbar intervertebral disc, be prepared from (every part of 10g) primarily of following bulk drugs: Cortex erythrinae 9 parts, Radix limonii sinensis 11 parts, Semen Strychni 8 parts, youth-and-old-age 10 parts, Radix Seu Caulis Mucunae Sempervirentis 9 parts, Herba Passiflorae Caeruleae 7 parts, Fructus Forsythiae 12 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 11 parts, Herba Lycopi 9 parts, Rhizoma Angiopteridis Fokiensis 8 parts, Herba Pyrolae 11 parts, Radix Ampelopsis Cantoniensis 9 parts, Saussurea cordifolia 10 parts, Herba Camptosori Sibirici 11 parts.Above-mentioned a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc is:
(1) get Semen Strychni and clean remove impurity, be placed in marmite, add rice washing decocting in water 28 minutes, take out together with Fructus Forsythiae, be placed in frying pan, intense fire stir-fries to surperficial zoom, pulverizes, and drench the crystal sugar water into crude drug quality 0.4 times, slow fire dries, and takes out;
(2) get Cortex erythrinae, Radix Seu Caulis Mucunae Sempervirentis, Rhizoma Angiopteridis Fokiensis, Radix Ampelopsis Cantoniensis and Saussurea cordifolia and pick up clean impurity, clear water is cleaned, and adds ginger slice, is placed in boiling water together and did not have medical material 2cm, airtight immersion 26 minutes, takes out and cuts into slices or section, and slow fire is dried, and pulverizes 120 mesh sieves;
(3) by clean to Radix limonii sinensis, youth-and-old-age, Herba Passiflorae Caeruleae, Radix achyranthis asperae (Herba Achyranthis Asperae), Herba Lycopi, Herba Pyrolae and Herba Camptosori Sibirici wash quickly, be placed in marmite, add the soak by water of boiled crude drug quality 6.5 times, big fire is heated to boiling, turn little fire to decoct 28 minutes, after filtration, collect filtrate, the water that filtering residue adds boiled crude drug quality 5 times decocts 20 minutes again, filters merging twice gained filtrate;
(4) step (1) (2) made crude drug is joined in step (3) gained filtrate, be evaporated to relative density be 1.18 thick paste (75 DEG C), add adjuvant mixing, make medicine carrying mastic, again through coating, cutting, leave standstill, packaging etc., make Chinese medicine patch.
embodiment 4treat a Chinese medicine patch for prolapse of lumbar intervertebral disc, be prepared from (every part of 10g) primarily of following bulk drugs: Cortex erythrinae 12 parts, Radix limonii sinensis 13 parts, Semen Strychni 13 parts, youth-and-old-age 12 parts, Radix Seu Caulis Mucunae Sempervirentis 10 parts, Herba Passiflorae Caeruleae 9 parts, Fructus Forsythiae 15 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 14 parts, Herba Lycopi 11 parts, Rhizoma Angiopteridis Fokiensis 12 parts, Herba Pyrolae 13 parts, Radix Ampelopsis Cantoniensis 12 parts, Saussurea cordifolia 13 parts, Herba Camptosori Sibirici 12 parts.Above-mentioned a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc is:
(1) get Semen Strychni and clean remove impurity, be placed in marmite, add rice washing decocting in water 32 minutes, take out together with Fructus Forsythiae, be placed in frying pan, intense fire stir-fries to surperficial zoom, pulverizes, and drench the crystal sugar water into crude drug quality 0.5 times, slow fire dries, and takes out;
(2) get Cortex erythrinae, Radix Seu Caulis Mucunae Sempervirentis, Rhizoma Angiopteridis Fokiensis, Radix Ampelopsis Cantoniensis and Saussurea cordifolia and pick up clean impurity, clear water is cleaned, and adds ginger slice, is placed in boiling water together and did not have medical material 2cm, airtight immersion 32 minutes, takes out and cuts into slices or section, and slow fire is dried, and pulverizes 140 mesh sieves;
(3) by clean to Radix limonii sinensis, youth-and-old-age, Herba Passiflorae Caeruleae, Radix achyranthis asperae (Herba Achyranthis Asperae), Herba Lycopi, Herba Pyrolae and Herba Camptosori Sibirici wash quickly, be placed in marmite, add the soak by water of boiled crude drug quality 7.5 times, big fire is heated to boiling, turn little fire to decoct 34 minutes, after filtration, collect filtrate, the water that filtering residue adds boiled crude drug quality 7 times decocts 20 minutes again, filters merging twice gained filtrate;
(4) step (1) (2) made crude drug is joined in step (3) gained filtrate, be evaporated to relative density be 1.22 thick paste (75 DEG C), add adjuvant mixing, make medicine carrying mastic, again through coating, cutting, leave standstill, packaging etc., make Chinese medicine patch.
Model case: xxx, women, 46 years old.Main suit: unbearably, both legs are numb, can not walk for flank pain; Medical history: patient's long campaigns physical work, waist was once subject to wound, and Short-term Pain aggravates, and thinks and has a relapse, then remove examination in hospital, showed 3-4 and saved prolapse of lumbar intervertebral disc, be diagnosed as prolapse of lumbar intervertebral disc through CT.
Introduce through friend and use this example gained Chinese medicine patch, be affixed on affected part, within one day, change once, within 15 days, be a course for the treatment of, after patient uses a course for the treatment of, pain starts to alleviate, and after continuing two courses for the treatment of of use, uncomfortable disease is eliminated substantially, patient fully recovers, and further consultation inspection, indices all recovers normal.
embodiment 5treat a Chinese medicine patch for prolapse of lumbar intervertebral disc, be prepared from (every part of 10g) primarily of following bulk drugs: Cortex erythrinae 10.5 parts, Radix limonii sinensis 12 parts, Semen Strychni 10.5 parts, youth-and-old-age 11 parts, Radix Seu Caulis Mucunae Sempervirentis 9.5 parts, Herba Passiflorae Caeruleae 8 parts, Fructus Forsythiae 13.5 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 12.5 parts, Herba Lycopi 10 parts, Rhizoma Angiopteridis Fokiensis 10 parts, Herba Pyrolae 12 parts, Radix Ampelopsis Cantoniensis 10.5 parts, Saussurea cordifolia 11.5 parts, Herba Camptosori Sibirici 11.5 parts.Above-mentioned a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc is:
(1) get Semen Strychni and clean remove impurity, be placed in marmite, add rice washing decocting in water 30 minutes, take out together with Fructus Forsythiae, be placed in frying pan, intense fire stir-fries to surperficial zoom, pulverizes, and drench the crystal sugar water into crude drug quality 0.45 times, slow fire dries, and takes out;
(2) get Cortex erythrinae, Radix Seu Caulis Mucunae Sempervirentis, Rhizoma Angiopteridis Fokiensis, Radix Ampelopsis Cantoniensis and Saussurea cordifolia and pick up clean impurity, clear water is cleaned, and adds ginger slice, is placed in boiling water together and did not have medical material 2cm, airtight immersion 29 minutes, takes out and cuts into slices or section, and slow fire is dried, and pulverizes 130 mesh sieves;
(3) by clean to Radix limonii sinensis, youth-and-old-age, Herba Passiflorae Caeruleae, Radix achyranthis asperae (Herba Achyranthis Asperae), Herba Lycopi, Herba Pyrolae and Herba Camptosori Sibirici wash quickly, be placed in marmite, add the soak by water of boiled crude drug quality 7 times, big fire is heated to boiling, turn little fire to decoct 31 minutes, after filtration, collect filtrate, the water that filtering residue adds boiled crude drug quality 6 times decocts 20 minutes again, filters merging twice gained filtrate;
(4) step (1) (2) made crude drug is joined in step (3) gained filtrate, be evaporated to relative density be 1.20 thick paste (75 DEG C), add adjuvant mixing, make medicine carrying mastic, again through coating, cutting, leave standstill, packaging etc., make Chinese medicine patch.
test example 1a kind of clinical practice for the treatment of the Chinese medicine patch (embodiment 5) of prolapse of lumbar intervertebral disc of gained of the present invention:
Choose crowd: in April ,-2015 in February, 2014, according to medical case history, have patient 284 example of prolapse of lumbar intervertebral disc six hospital's screenings, age 30-64 year, 42.8 ± 3.4 years old mean age, the course of disease 20 days-10 years, wherein male patient 152 example, female patient 132 example.Inclusive criteria: all patients are diagnosed as prolapse of lumbar intervertebral disc through symptom, sign and CT, and discharge and have serious organ's property disease, has lumbar spinal stenosis, lumbar vertebra deformity, lumbar spondylolisthesis, fails the patient treated on request.
Before test, patient is divided into two groups at random, experimental group 186 example and matched group 98 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group uses products obtained therefrom of the present invention, is affixed on affected part, within one day, changes once, within 15 days, is a course for the treatment of; Matched group uses other conventional medicines (unblocking collaterals to treat arthritis subsides, YAOTONGNING JIAONANG, YUNNAN BAIYAO cream, " Yaobitong Capsule" etc.).Treatments period carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: lumbago and skelalgia symptom and sign disappear, and waist is movable normal, can normally work and live; (2) effective: lumbago and skelalgia symptom and sign obviously alleviate, waist is movable obviously to be improved, and can do light activity; (3) take a turn for the better: lumbago and skelalgia symptom and sign alleviate to some extent, can not work for a long time; (4) invalid: lumbago and skelalgia symptom and sign are without improvement or increase the weight of.
Clinical effectiveness: after the treatment of three courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1: (total effective rate=cure rate+obvious effective rate+improvement rate)
As shown in Table 1, the total effective rate of experimental group is 97.8%, and the total effective rate 84.7% of matched group, be starkly lower than the therapeutic effect of experimental group, illustrate that products obtained therefrom of the present invention is evident in efficacy, cure rate is high.
During two groups of patient treatments, none routine untoward reaction person of experimental group, and matched group has 7 examples to occur anaphylaxis, can take a turn for the better after drug withdrawal; After treating half a year, follow up a case by regular visits to two groups of patients, experimental group only has 1 example recurrence, and matched group patients with recurrent reaches 12 examples, and products obtained therefrom treating both the principal and secondary aspects of a disease of the present invention is described, safe and non-stimulating.
The Chinese medicine used in the present invention, comprise the Cortex erythrinae of dispelling wind and removing obstruction in the collateral, the Radix limonii sinensis of blood circulation promoting and blood stasis dispelling, Herba Camptosori Sibirici, the Semen Strychni of reducing swelling and alleviating pain, the youth-and-old-age of clearing away heat-damp and promoting diuresis, the Radix Seu Caulis Mucunae Sempervirentis of promoting blood flow to regulate menstruation, the Herba Passiflorae Caeruleae of promoting blood circulation and stopping pain, the Fructus Forsythiae of dispersing swelling and dissipating binds, the Radix achyranthis asperae (Herba Achyranthis Asperae) of blood circulation promoting and blood stasis dispelling, the Herba Lycopi of blood stasis dispelling eliminating carbuncle, ease pain the Rhizoma Angiopteridis Fokiensis of calming the nerves, the Herba Pyrolae of the kidney invigorating bone strengthening, dispel the wind the Radix Ampelopsis Cantoniensis of removing dampness, the Saussurea cordifolia of expelling wind and cold, multiple medical material synergism, plays effect of dispelling wind and removing obstruction in the collateral, promoting blood circulation and stopping pain altogether.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. treat a Chinese medicine patch for prolapse of lumbar intervertebral disc, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Cortex erythrinae 8-13; Radix limonii sinensis 10-14; Semen Strychni 6-15; Youth-and-old-age 9-13; Radix Seu Caulis Mucunae Sempervirentis 7-12; Herba Passiflorae Caeruleae 6-10; Fructus Forsythiae 11-16; Radix achyranthis asperae (Herba Achyranthis Asperae) 9-16; Herba Lycopi 8-12; Rhizoma Angiopteridis Fokiensis 6-14; Herba Pyrolae 9-15; Radix Ampelopsis Cantoniensis 7-14; Saussurea cordifolia 8-15; Herba Camptosori Sibirici 10-13.
2. a kind of Chinese medicine patch for the treatment of prolapse of lumbar intervertebral disc as claimed in claim 1, is characterized in that, Cortex erythrinae 9-12; Radix limonii sinensis 11-13; Semen Strychni 8-13; Youth-and-old-age 10-12; Radix Seu Caulis Mucunae Sempervirentis 9-10; Herba Passiflorae Caeruleae 7-9; Fructus Forsythiae 12-15; Radix achyranthis asperae (Herba Achyranthis Asperae) 11-14; Herba Lycopi 9-11; Rhizoma Angiopteridis Fokiensis 8-12; Herba Pyrolae 11-13; Radix Ampelopsis Cantoniensis 9-12; Saussurea cordifolia 10-13; Herba Camptosori Sibirici 11-12.
3. a kind of Chinese medicine patch for the treatment of prolapse of lumbar intervertebral disc as claimed in claim 1, is characterized in that, Cortex erythrinae 10.5; Radix limonii sinensis 12; Semen Strychni 10.5; Youth-and-old-age 11; Radix Seu Caulis Mucunae Sempervirentis 9.5; Herba Passiflorae Caeruleae 8; Fructus Forsythiae 13.5; Radix achyranthis asperae (Herba Achyranthis Asperae) 12.5; Herba Lycopi 10; Rhizoma Angiopteridis Fokiensis 10; Herba Pyrolae 12; Radix Ampelopsis Cantoniensis 10.5; Saussurea cordifolia 11.5; Herba Camptosori Sibirici 11.5.
4. a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc as described in as arbitrary in claim 1-3, it is characterized in that, step is as follows:
(1) get Semen Strychni and clean remove impurity, be placed in marmite, it is (preferred: to boil 28-32 minute to add rice washing decocting in water 25-35 minute; Be more preferably: boil 30 minutes), take out together with Fructus Forsythiae, be placed in frying pan, intense fire stir-fries to surperficial zoom, pulverizes, and drench into crystal sugar water, slow fire dries, and takes out;
(2) get Cortex erythrinae, Radix Seu Caulis Mucunae Sempervirentis, Rhizoma Angiopteridis Fokiensis, Radix Ampelopsis Cantoniensis and Saussurea cordifolia and pick up clean impurity, clear water is cleaned, and adds ginger slice, is placed in boiling water together and did not have medical material 2cm, airtight immersion, takes out and cuts into slices or section, and slow fire is dried, and pulverizes and sieves;
(3) by clean to Radix limonii sinensis, youth-and-old-age, Herba Passiflorae Caeruleae, Radix achyranthis asperae (Herba Achyranthis Asperae), Herba Lycopi, Herba Pyrolae and Herba Camptosori Sibirici wash quickly, be placed in marmite, decoct with water, big fire is heated to boiling, turn little fire to decoct, after filtration, collect filtrate, filtering residue adds boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) and again decocts 20 minutes, filters merging twice gained filtrate;
(4) step (1) (2) made crude drug is joined in step (3) gained filtrate, is evaporated to thick paste, add adjuvant mixing, make medicine carrying mastic, then through coating, cutting, leave standstill, packaging etc., make Chinese medicine patch.
5. a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc as claimed in claim 4, it is characterized in that, step (1) amount of drenching into crystal sugar water be the 0.3-0.6 of crude drug quality doubly (preferred: the amount of drenching into crystal sugar water be the 0.4-0.5 of crude drug quality doubly; Be more preferably: the amount of drenching into crystal sugar water is 0.45 times of crude drug quality).
6. a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc as claimed in claim 4, is characterized in that, step (2) airtight immersion 22-36 minute is (preferred: airtight immersion 26-32 minute; Be more preferably: airtight immersion 29 minutes).
7. a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc as claimed in claim 4, is characterized in that, it is (preferred: to pulverize 120-140 mesh sieve that step (2) pulverized 100-160 mesh sieve; Be more preferably: pulverized 130 mesh sieves).
8. a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc as claimed in claim 4, is characterized in that, the 6-8 that step (3) amount of water is boiled crude drug quality is doubly (preferred: the 6.5-7.5 that amount of water is boiled crude drug quality doubly; Be more preferably: amount of water is 7 times of boiled crude drug quality).
9. a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc as claimed in claim 4, is characterized in that, step (3) turn little fire decoct 24-38 minute (preferred: to turn little fire and decoct 28-34 minute; Be more preferably: turn little fire and decoct 31 minutes).
10. a kind of preparation method for the treatment of the Chinese medicine patch of prolapse of lumbar intervertebral disc as claimed in claim 4, is characterized in that, it is (preferred: to be evaporated to the thick paste that relative density is 1.18-1.22 that step (4) is evaporated to the thick paste that relative density is 1.14-1.26; Be more preferably: be evaporated to the thick paste that relative density is 1.20).
CN201510483034.5A 2015-08-10 2015-08-10 Traditional Chinese medicine plaster treating lumbar disc herniation and manufacturing method Withdrawn CN104997951A (en)

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Application publication date: 20151028