CN104817519B - 一类ca-4的衍生物、其制法及其医药用途 - Google Patents

一类ca-4的衍生物、其制法及其医药用途 Download PDF

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Publication number
CN104817519B
CN104817519B CN 201510235806 CN201510235806A CN104817519B CN 104817519 B CN104817519 B CN 104817519B CN 201510235806 CN201510235806 CN 201510235806 CN 201510235806 A CN201510235806 A CN 201510235806A CN 104817519 B CN104817519 B CN 104817519B
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acid
arh
2h
lh
ethyl acetate
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CN 201510235806
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Chinese (zh)
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CN104817519A (zh )
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徐云根
刘坤
宋晓翰
陈泓竹
张宏波
张灵芝
朱启华
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中国药科大学
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CN 201510235806 2015-05-11 2015-05-11 一类ca-4的衍生物、其制法及其医药用途 CN104817519B (zh)

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Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006138427A2 (en) * 2005-06-14 2006-12-28 Baylor University Combretastatin analogs with tubulin binding activity
WO2009118474A1 (fr) * 2008-02-28 2009-10-01 Sanofi-Aventis Procede de preparation de combretastatine
EP2338877A1 (en) * 2009-12-15 2011-06-29 The Provost, Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin Combretastatin Derivatives and Uses Therefor
CN102219811A (zh) * 2011-04-14 2011-10-19 中国药科大学 Ca-4衍生物、其制法及其医药用途
CN102249987A (zh) * 2011-05-06 2011-11-23 兰州大学 一种考布他汀类化合物及其制备方法和用途
CN102863472A (zh) * 2012-10-15 2013-01-09 中国海洋大学 考布他汀a-4类似物及其制备方法和在制备抗肿瘤药物中的应用
CN102906076A (zh) * 2009-12-03 2013-01-30 赛诺菲 考布他汀衍生物制备方法
WO2013026942A1 (en) * 2011-08-25 2013-02-28 The Provost, Fellows, Foundation Scholars, And The Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin Tubulin binding agents
CN102985410A (zh) * 2010-05-05 2013-03-20 拜罗伊特大学 在癌症的治疗中使用的考布他汀类似物
CN103421057A (zh) * 2013-08-14 2013-12-04 合肥医工医药有限公司 康普瑞汀氨基糖缀合物、其制法及其医药用途
CN103524349A (zh) * 2013-10-19 2014-01-22 山东大学 Ca-4碳酸酯类衍生物、其制备方法、药物组合物与医药用途
WO2014181085A1 (en) * 2013-05-09 2014-11-13 Kenneth Dawson Bagshawe Tumour therapy

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006138427A2 (en) * 2005-06-14 2006-12-28 Baylor University Combretastatin analogs with tubulin binding activity
WO2009118474A1 (fr) * 2008-02-28 2009-10-01 Sanofi-Aventis Procede de preparation de combretastatine
CN102906076A (zh) * 2009-12-03 2013-01-30 赛诺菲 考布他汀衍生物制备方法
EP2338877A1 (en) * 2009-12-15 2011-06-29 The Provost, Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin Combretastatin Derivatives and Uses Therefor
CN102985410A (zh) * 2010-05-05 2013-03-20 拜罗伊特大学 在癌症的治疗中使用的考布他汀类似物
CN102219811A (zh) * 2011-04-14 2011-10-19 中国药科大学 Ca-4衍生物、其制法及其医药用途
CN102249987A (zh) * 2011-05-06 2011-11-23 兰州大学 一种考布他汀类化合物及其制备方法和用途
WO2013026942A1 (en) * 2011-08-25 2013-02-28 The Provost, Fellows, Foundation Scholars, And The Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin Tubulin binding agents
CN102863472A (zh) * 2012-10-15 2013-01-09 中国海洋大学 考布他汀a-4类似物及其制备方法和在制备抗肿瘤药物中的应用
WO2014181085A1 (en) * 2013-05-09 2014-11-13 Kenneth Dawson Bagshawe Tumour therapy
CN103421057A (zh) * 2013-08-14 2013-12-04 合肥医工医药有限公司 康普瑞汀氨基糖缀合物、其制法及其医药用途
CN103524349A (zh) * 2013-10-19 2014-01-22 山东大学 Ca-4碳酸酯类衍生物、其制备方法、药物组合物与医药用途

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