CN104815123A - Skin wound healing agent - Google Patents

Skin wound healing agent Download PDF

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Publication number
CN104815123A
CN104815123A CN201510200756.5A CN201510200756A CN104815123A CN 104815123 A CN104815123 A CN 104815123A CN 201510200756 A CN201510200756 A CN 201510200756A CN 104815123 A CN104815123 A CN 104815123A
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CN
China
Prior art keywords
wound
healing agent
radix
skin wound
azone
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Pending
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CN201510200756.5A
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Chinese (zh)
Inventor
杨孝良
王竞鹏
赵锋
孙刚
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Individual
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Individual
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Priority to CN201510200756.5A priority Critical patent/CN104815123A/en
Publication of CN104815123A publication Critical patent/CN104815123A/en
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a skin wound healing agent which is prepared from traditional Chinese medicine raw materials including, by weight, 6-8g of forsythia, 6-8g of honeysuckle, 6-8g of dried alum, 10-14g of dioscorea hispida, 10-14g of semen strychni powder, 10-14g of elegant Jessamine, 10-14g of radix ampelopsis, 10-14g of gallnut, 10-14g of borneol, 6-8g of jasmine, 6-8g of patience dock root, 6-8g of native horse mane and 10-14g of azone. The raw materials are grinded into ointment applied to an affected part, heat can be cleared, toxicity can be removed, pain is relieved, stasis is removed, tissue regeneration is promoted, a blood flow state is improved, wound tissue growth is promoted, skins can be smooth, and a wound is repaired.

Description

A kind of healing agent for skin wound surface
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly a kind of healing agent for skin wound surface.
Background technology
People often can because some be unexpected in production, life; burned skin in various degree; burnt degree is effectively treated skin as not timely; obvious hypertrophy cicatrix can be produced; hypertrophy cicatrix causes larger impact to the life of people, body outward appearance, and hypertrophy cicatrix generally all with more serious gargalesthesia, can affect the orthobiosis of people; medicine major part at present in treatment burn burn wound is postoperative use, misses the best opportunity for the treatment of.
Summary of the invention
The object of the present invention is to provide and a kind ofly treat deep burn, the consolidant of the situation burn wound such as wound surface has large area tendon, nerve, osseous tissue, blood vessel injury or expose.Adopt this medicine can impel the cell regeneration of affected tissue, blood circulation promoting and blood stasis dispelling, granulation promoting, impel wound surface quickly-healing.
Healing agent for skin wound surface of the present invention, is characterized in that being formed by the Chinese medicine proportioning of following parts by weight: Fructus Forsythiae 6-8g, Flos Lonicerae 6-8g, dried Alumen 6-8g, Rhizoma Dioscoreae hispidae 10-14g, Semen Strychni Pulveratum 10-14g, Herba Gelsemii Elegantis 10-14g, Radix Ampelopsis 10-14g, Galla Chinensis 10-14g, Borneolum Syntheticum 10-14g, Fructus Gardeniae 6-8g, Radix Rumicis Patientiae 6-8g, Tu Ma Zong 6-8g and azone 10-14g.
As preferably, prepare by following parts by weight:
Fructus Forsythiae 8g, Flos Lonicerae 6g, dried Alumen 7g, Rhizoma Dioscoreae hispidae 12g, Semen Strychni Pulveratum 12g, Herba Gelsemii Elegantis 12g, Radix Ampelopsis 12g, Galla Chinensis 12g, Borneolum Syntheticum 12g, Fructus Gardeniae 8g, Radix Rumicis Patientiae 8g, Tu Ma Zong 8g and azone 10-14g.
Chinese medicine of the present invention, obtains as follows:
1) take yellow calamite, Radix seu Herba Tetrastigmatis Hypoglauci, Radix Pittospori, Herba Lysimachiae Circaeoidis, Radix Chimonanthi praecocis, Folium seu Radix Rubi Ichangensis and Myrrha by above-mentioned parts by weight, mix homogeneously, cut into slices or be ground into particle diameter 0.5-1.5cm size, for subsequent use;
2) get vegetable oil and be placed in pot, by step 1) Chinese crude drug input, heating is also continuous stirs, and is heated to 220 DEG C, explodes to surperficial dark brown inside is sallow until spice, fried well rear elimination medicinal residues, and the oil after removing slag is medicine oil;
3) get above-mentioned medicine oil to continue to temper, treat that oil temperature rises to 320 DEG C, use slow fire instead, until oil bloom are assembled to pot central authorities, get a little medicine oil droplet in water, be not shattered into pearl, can stop tempering;
4) take dried Alumen, Pulvis concha Anodonta seu Cristaria, Cera Flava, ray gallbladder, Semen Momordicae pulverize, cross 120 mesh sieves for subsequent use;
5) to step 3) drop into step 4 in obtained medicine oil) obtained powder, drop into azone and stir to paste, obtained healing agent for skin wound surface of the present invention.Usage: be applied on gauze and apply affected part, every day 3-5 time.
Pharmacology analysis: Fructus Forsythiae, Flos Lonicerae, dried Alumen and Rhizoma Dioscoreae hispidae heat-clearing and toxic substances removing, anti-inflammation in side; Semen Strychni Pulveratum, Herba Gelsemii Elegantis disappear pain eliminating stagnation; Radix Ampelopsis, Galla Chinensis convergence granulation promoting; Borneolum Syntheticum clearing away heat to alleviate pain, sensible granulation promoting; Fructus Gardeniae, Radix Rumicis Patientiae, Tu Ma Zong clearing away heat and cooling blood, hemostasis; Azone, as a kind of transdermal enhancer, promotes Drug Percutaneous Absorption.
All medicines share, and get final product heat-clearing and toxic substances removing, and the pain that disappears eliminating stagnation, granulation promoting, improve blood flow state, promotes wound tissue growth, can separately skin is smooth, wound repairing.
Dried Alumen: expectorant, dampness, antidiarrheal, hemostasis, removing toxic substances, parasite killing.Control epilepsy, sore throat, remorse saliva is stopped up very, hepatitis, jaundice, general edema with yellowish skin taste-blindness rate, uterine prolapse, leucorrhea, dysentery, epistaxis, aphtha of the mouth and tongue, skin ulcer hemorrhoid scabies, water, fire, insect bite.
Fructus Forsythiae: bitter, is slightly cold.Return lung, the heart, small intestine meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.
Flos Lonicerae: sweet, cold.Return lung, the heart, stomach warp.Heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.
Rhizoma Dioscoreae hispidae: sweet is cool.Poisonous.Removing toxic substances and promoting subsidence of swelling, blood stasis removing stops blooding.Sore and toxic is controlled in external, osteopatia sprain, traumatic hemorrhage.
Semen Strychni Pulveratum: bitter, temperature; Very toxic.Return liver, spleen channel.Removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.For rheumatoid arthritis stubborn, paralysis and numbness, injury from falling down, ulcer sore pain; Poliomyelitis sequela, rheumatoid arthritis.
Herba Gelsemii Elegantis: arduous, temperature, poisonous.Dispel the wind, counteracting toxic substances, detumescence, pain relieving.Control mange, eczema, scrofula, carbuncle, furuncle, traumatic injury, rheumatic arthralgia, neuralgia.
Radix Ampelopsis: bitter, is slightly cold.GUIXIN, stomach warp.Heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.For carbuncle carbuncle on the back, furuncle, scrofula, burn due to hot liquid or fire.
Galla Chinensis: sour, puckery, cold.Return lung, large intestine, kidney channel.Astringe the lung pathogenic fire reducing, relieving diarrhea with astringents, arresting sweating stops blooding, removing dampness sore.For chronic cough of deficiency lung, lung-heat phlegmatic cough, chronic diarrhea chronic dysentery, night sweat, quenches one's thirst, hemorrhoidal bleeding of having blood in stool, traumatic hemorrhage, carbuncle sore tumefacting virus, Skin wet and rotten.
Borneolum Syntheticum: pungent, bitter, is slightly cold.GUIXIN, spleen, lung meridian.To have one's ideas straightened out refreshment, clearing away heat to alleviate pain.Faint for calentura coma, convulsion, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, and conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.
Fructus Gardeniae: bitter, cold.GUIXIN, lung, tri-jiao channel.Pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, jaundice dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.
Radix Rumicis Patientiae: bitter, sour, cold.Cooling blood for hemostasis, heat-clearing and toxic substances removing, parasite killing.For dysfunctional uterine hemorrhage, spit blood, spitting of blood, epistaxis, gingival hemorrhage, tail, duodenal hemorrhage, have blood in stool, purpura, constipation, edema; Scabies is controlled in external, furuncle, seborrheic dermatitis.
Tu Ma Zong: bitter, cool.Heat-clearing and toxic substances removing, cooling blood for hemostasis.Do not move back for heat of a specified duration, night sweat, epistaxis, spitting of blood, spit blood, have blood in stool, metrorrhagia, traumatic injury; Furuncle is controlled in external.
Chinese medicine formula of the present invention, all medicine compatibilities, anti-inflammation and sterilization, can impel the cell regeneration of affected tissue, blood circulation promoting and blood stasis dispelling, goes convergence, sensible granulation promoting, without anaphylaxis, impels wound surface quickly-healing, and preparation is simple, with low cost.
Efficacy assessment standard:
Wound healing refers to that body suffers External Force Acting, and the process more again after disconnected or defect appears in the tissue such as skin, is to comprise the complex combination that the regeneration of various tissue and granulation tissue hyperplasia, scar tissue formed, and shows the synergism of various process.
First degree wound is only limitted to skin epidermis, and slightly severe one has skin and subcutaneous tissue fracture, and occurs wound; Serious wound can have muscle, tendon, neural fracture and fracture.
The mensuration of wound surface:
With sterilization translucent oleic acid paper be affixed on wound surface, along edge of wound line, then be affixed on graph paper calculate survey area, as wound original area.Then after wound, 3,7,10,14,21d surveys wound revolution mark, calculates revolution mark percentage rate=revolution mark/original area × 100%.
Therapeutic outcome: burned patient 40 example, be divided into matched group and experimental group, often organize 20 people, matched group gives outer painting salve for treating burn and scald, is applied in affected part equably, every day 3-4 time.Experimental group is coated with wound healing agent of the present invention outward, every day 3-4 time.
3d 7d 10d 14d 21d
Experimental group 82±3.5 66±3.1 37±3.5 12±2.3 2±1.5
Matched group 83±2.2 79±3.2 48±2.2 28±3.2 9±1.2
Experiment conclusion: use Chinese medicine wound healing of the present invention agent comparatively matched group, wound healing is faster, and healing effect is better.
Detailed description of the invention
Embodiment 1
Healing agent for skin wound surface of the present invention, is characterized in that being formed by the Chinese medicine proportioning of following parts by weight: Fructus Forsythiae 8g, Flos Lonicerae 6g, dried Alumen 7g, Rhizoma Dioscoreae hispidae 12g, Semen Strychni Pulveratum 12g, Herba Gelsemii Elegantis 12g, Radix Ampelopsis 12g, Galla Chinensis 12g, Borneolum Syntheticum 12g, Fructus Gardeniae 8g, Radix Rumicis Patientiae 8g, Tu Ma Zong 8g and azone 10-14g.
Chinese medicine formula of the present invention, prepare as follows and use:
1) take yellow calamite, Radix seu Herba Tetrastigmatis Hypoglauci, Radix Pittospori, Herba Lysimachiae Circaeoidis, Radix Chimonanthi praecocis, Folium seu Radix Rubi Ichangensis and Myrrha by above-mentioned parts by weight, mix homogeneously, cut into slices or be ground into particle diameter 1.0cm size, for subsequent use;
2) get vegetable oil and be placed in pot, by step 1) Chinese crude drug input, heating is also continuous stirs, and is heated to 220 DEG C, explodes to surperficial dark brown inside is sallow until spice, fried well rear elimination medicinal residues, and the oil after removing slag is medicine oil;
3) get above-mentioned medicine oil to continue to temper, treat that oil temperature rises to 320 DEG C, use slow fire instead, until oil bloom are assembled to pot central authorities, get a little medicine oil droplet in water, be not shattered into pearl, can stop tempering;
4) take dried Alumen, Pulvis concha Anodonta seu Cristaria, Cera Flava, ray gallbladder, Semen Momordicae pulverize, cross 120 mesh sieves for subsequent use;
5) to step 3) drop into step 4 in obtained medicine oil) obtained powder, drop into azone and stir, obtained healing agent for skin wound surface of the present invention.Usage: be applied on gauze and apply affected part, every day 5 times.

Claims (2)

1. a healing agent for skin wound surface, is characterized in that being formed by the Chinese medicine proportioning of following parts by weight: Fructus Forsythiae 6-8g, Flos Lonicerae 6-8g, dried Alumen 6-8g, Rhizoma Dioscoreae hispidae 10-14g, Semen Strychni Pulveratum 10-14g, Herba Gelsemii Elegantis 10-14g, Radix Ampelopsis 10-14g, Galla Chinensis 10-14g, Borneolum Syntheticum 10-14g, Fructus Gardeniae 6-8g, Radix Rumicis Patientiae 6-8g, native horse Zong 6-8g and azone 10-14g.
2. healing agent for skin wound surface according to claim 1, is characterized in that being formed by the Chinese medicine proportioning of following parts by weight: Fructus Forsythiae 8g, Flos Lonicerae 6g, dried Alumen 7g, Rhizoma Dioscoreae hispidae 12g, Semen Strychni Pulveratum 12g, Herba Gelsemii Elegantis 12g, Radix Ampelopsis 12g, Galla Chinensis 12g, Borneolum Syntheticum 12g, Fructus Gardeniae 8g, Radix Rumicis Patientiae 8g, Tu Ma Zong 8g and azone 10-14g.
CN201510200756.5A 2015-04-23 2015-04-23 Skin wound healing agent Pending CN104815123A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177666A (en) * 2016-09-07 2016-12-07 无比滴(广东)药业有限公司 A kind of external preparation promoting child skin to heal

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1586521A (en) * 2004-07-23 2005-03-02 罗培省 Healing agent for skin wound surface

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1586521A (en) * 2004-07-23 2005-03-02 罗培省 Healing agent for skin wound surface

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177666A (en) * 2016-09-07 2016-12-07 无比滴(广东)药业有限公司 A kind of external preparation promoting child skin to heal

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Application publication date: 20150805

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