CN104770862A - Selenium and germanium enriched nanometer plant medicine stone nicotine-free and tar-free cigarette - Google Patents
Selenium and germanium enriched nanometer plant medicine stone nicotine-free and tar-free cigarette Download PDFInfo
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Abstract
The invention discloses a selenium and germanium enriched nanometer plant medicine stone nicotine-free and tar-free cigarette, and belongs to the technical field of modern high-technology nanometer plant medicine stone health care cigarette preparation and production. Pine tree zeolite is used for resisting special changes and restraining nitrosamine so as to resisting cancers; pine needle medical stone is used for filtering toxin so as to reduce cigarette harms and removing free radical nicotine; oriental arborvitae sepiolite is used for removing the cigarette harm of tar and restraining benzopyrene; Pinus densiflora tourmaline is used for removing the tar, reducing the harm and resisting to polycyclic aromatic hydrocarbon and the cancers; masson pine montmorillonite is used for removing the tar and removing free radical nicotine cigarette toxin; Korean pine opal is used for removing toxin in carbon monoxide and nitric oxide; and selenium and the germanium enriched pine tree plant medicine stone series is used for removing the smoke, the cigarette harm and the toxin in the nitrosamine, and in this way, the nicotine-free and tar-free cigarette is formed. At least one hundred thousands free radicals will be generated when a person smoke one time, the cells of the human body are damaged, and the health of the human body is injured; by means of the selenium and germanium enriched nanometer plant medicine stone nicotine-free and tar-free cigarette, antioxidant and antimutation can be effectively achieved, the free radicals are removed, the smoke and the cigarette harm are reduced, aging resistance is achieved, diseases are resisted, the cancer is prevented, and the health is protected.
Description
Technical field:
The invention discloses a kind of rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is belong to modern high technology nanometer autonomic drug stone health-care cigarette preparation production technical field.
Background technology:
The cancer of the mankind 35% is relevant with smoking with the lung cancer of 85%, and except cancer, smoking also causes multiple serious disease.Show the research of cigarette, cigarette burning can produce 4000 number of chemical materials, and wherein more than 40 kinds have clear and definite mutagenesis/carcinogenicity.Main carcinogenic substance has tobacco-specific nitrosamine (TSNA), benzo (a) pyrene, polycyclic aromatic hydrocarbon (PAH), aromatic hydrocarbon, benzene, bioxin, catechol and carcinogenic quinone, hydrazine class etc.TSNA be nicotine by nitrosifying product, 4-(Methylnitrosamino)-3-pyridine-1-butanone (NNK) is the carcinogen that known 7 kinds of TSNA kinds are the strongest.NNK exists all in a large number in main flow, side-stream smoke and incombustible tobacco.NNK is the carcinogenic outstanding feature thing of cigarette, and nicotine is the main cause of smoking addiction.
Free radical damage theory has deepened the understanding to harmfulness of smoking.The elevated chemical activity of free radical discloses a lot of carcinogenic oncogenic pathways essence.Free radical plays a very important role in the startup of tumour, promotion and evolution, and nearly all chemical carcinogen all can generate free radical by enzyme effect.Free radical runs through all the time as indispensable intermediate and is active among the gas phase of cigarette burning and condensed phase reaction.
The main of cigarette is harmful to formation, accumulation, the harm of nitrosamine, BaP, free radical, carbon monoxide (and endotoxin of recent years abroad discovery) etc. and suppresses to produce.Nicotine is mainly had an effect to central nervous system and neuro nerve cell and motor nerve ending, nicotine on neuron membrane nicotine type acetylcholinergic receptor in conjunction with time, because nicotine structure Semi-polarity partial dissociation becomes cation, it is combined with the anionic site of electrostatic attraction and acceptor and hydrophobic bond, makes the pyridine base being in certain distance act on receptor membrane and produce toxic action.As can be seen here, in the toxicity of nicotine and its molecular structure, the distance of each group and group has relation, this can explain mutual Nicotine doses-effect relation, and the nicotine of low dosage can produce excitation, and the nicotine of high dose then produces suppression and paralysis effect.Nicotine is mainly through promoting atherosclerotic, thrombosis or causing paralysis by the self-regulating function of damage brain.Nicotine causes subarachnoid hemorrhage by shrinking or promote the arteriolar thrombosis of nutrition, affects the function of brain by affecting cerebral blood circulation; Smoking can accelerate the atherosclerotic of crown tip.
Nicotine can cause adrenal gland body to discharge adrenaline and noradrenalin, and the main harm of smoking to heart and blood vessel may be exactly because caused by the release of this hormone.Nicotine can control blood pressure, heart rate, painstaking effort output quantity via stomodaeal nervous system, makes them increase in short-term, and nicotine can make painstaking effort output quantity and cardiac contractility reduce, and blood vessel reduces simultaneously, and can cause cardiac arrhythmia.Nicotine causes the trend that in blood, fatty acid concentration rises in addition, some result of study is thought simultaneously, nicotine adds the mutual tendency of sticking of blood platelet in blood, and this effect can be arrived at the Early observation of thrombosis blood clotting, and to form atherosclerotic in artery relevant.Nicotine is forming acting on it and cause adrenergic release to be associated in atherosclerosis process, and this hormone can promote biologically active pdgf.Nicotine also can make fibrinogen in blood plasma rise, because this increasing the danger suffering from ischemic heart disease.
Summary of the invention:
The object of the present invention is to provide a kind of rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette.
The scheme that the technology of the present invention solves is:
A kind of rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: form % by following masses proportioning
(1) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: become by the anti-spy of pine tree zeolite and suppress the anticancer nicotine-free non-tar cigarette of nitrosamine, by following masses proportioning composition %
(2) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: filter poison by pine needle medical stone and reduce damage by fume freeradical nicotine nicotine-free non-tar cigarette, by following masses proportioning composition %
(3) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: by arbor-vitae sepiolite except damage by fume tar suppresses BaP nicotine-free non-tar cigarette, by following masses proportioning composition %
(4) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: by arbor-vitae sepiolite except damage by fume tar suppresses BaP nicotine-free non-tar cigarette, by following masses proportioning composition %
(5) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: by the anticancer nicotine-free non-tar cigarette of the anti-polycyclic aromatic hydrocarbon of Japanese red pine tourmaline decoking harm reduction, by following masses proportioning composition %
(6) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: by masson pine montmorillonite tar removing freeradical BaP cigarette poison nicotine-free non-tar cigarette, by following masses proportioning composition %
(7) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: by the clear flue gas damage by fume nitrosamine endotoxin nicotine-free non-tar cigarette of rich selenium germanium Pine plants remedies series, by following masses proportioning composition %
Preparation method and explanation:
Pine tree series natural plant in the various embodiments described above (1)-(7) and remedies series are carried out pulverizing respectively and makes water that 80 object meal add 8 times and make mixing and be suspended in mixing in colloid mill and carry out micronization processes, refinement liquid is placed in homogenizer again to carry out even refinement again and carries out nanometer pulverizing, be added in the pipe tobacco that cigarette produces with the nano micromolecule that nano molecular to be refined into nanometer particle size 0.1-2 μm by Nano Particle ultramicronising device again and each prescription pine tree natural plants remedies in cigarette paper and cigaratte filter, the nano micromolecule of this ultra micro granulation accelerates cigarette combustion degree and substantially increases flue gas, the absorption of nicotine and heavy metal in flue gas, decoking falls evil effect obviously, bioavilability, drug effect has the progress of breakthrough, with any medical cigarette cannot compared with, nano micromolecule enters in human body, transport is in vivo more convenient, remedies effect is more fully manifested, give play to nano micromolecule interaction effect in the medicine and cigarette smoke with peculiar effect.
Why " Smoking is harmful to your health "? reason is: containing many oxidants and prooxidant in the smog of result of combustion of tobacco, they can cause the generation of free radical, and its activity is very high.Relevant expert studies announcement, and smoking produces free radical mode the most maximum at present, often has a suck of cigarette and produces 100,000 free radicals to I haven't seen you for ages.This free radical can damage human body cell.In smoking process, contained oxidant or prooxidant in the tar state of not only tobacco.And in the gaseous state of tobacco contained oxidant or prooxidant more.Smoking that Here it is significantly can increase the risk factors of lipid peroxy agent effect, thus becomes the major reason of " Smoking is harmful to your health ".
Why can rich selenium cigarette just improve tobacco quality security and reduce harmfulness of smoking again? this because, improve the selenium content of cigarette, not only can improve the formation that smoker's blood selenium level is conducive to selenoenzyme in body, but also content and the toxicity of cigarette coke tar can be reduced, the concentration of free radical in flue gas when can also reduce cigarette combustion.
Be conducive in the formation of selenoenzyme improving blood selenium level in smoker body: the free radical causing generation by multiple oxidant institute, can cause the damage of biomolecule and cell membrane.Medical circle is thought, the free radical be inhaled in human body can directly be combined with DNA, makes cell transformation, thus causes disease and canceration.In order to deal with the destruction of these multiple oxidants, in body, the existence of different approaches detoxication mechanisms is just very important.Two kinds of systems eliminating free radical are had, i.e. enzymatic system and non-enzymatic system in human body.Selenoenzyme such as glutathione peroxidase and sulphur draw the systems such as reductase proteins to be to remove the important enzyme of interior free yl.Inhaling rich selenium cigarette can make the human body blood selenium of the human body blood selenium level person that comparatively aspirates regular-size cigarette improve 10%; show that the selenium of main flume can enter human body and participate in blood circulation; improve the activity of these important enzymes removing interior free yl; protected protein matter and DNA macromolecular structure and function are from the damage of free radical; play the effect reducing gene mutation, DNA plerosis, thus just reduce the harm of cigarette to human body.
In the content reducing cigarette coke tar and toxicity: research shows, in cigarette, natural selenium selenium content and tar content are negative correlativing relation, especially Se content when 0.1 μ g/g-1.0 μ g/g scope in flue gas number of free radical decline obviously, meanwhile, also because selenium can suppress 3, the Cancer-causing mutation effect of 4-BaP, makes toxicity also decrease.
Tobacco leaf is owing to being subject to the pollution of its growing environment and the impact of tobacco leaf self species characteristics, the harmful elements such as a certain amount of heavy metal are contained in capital, as plumbous (Pb), chromium (Cr), cadmium (Cd), mercury (Hg) etc.Selenium effectively can adsorb antagonism heavy metal element and reduce its harm.
Nanometer selenium is the Selenium supplement agent of a kind of renewal after Organic Selenium, has the advantages such as high bioactivity, high security index, high-tech content, high-purity, high stability, is succeeded in developing by Chinese University of Science and Technology.Nanometer selenium shows magical biologically active.Biologic test proves, on the one hand, the acute toxicity of nanometer selenium is 1/7 of inorganic selenium, 1/3 of Organic Selenium; On the other hand, with inorganic selenium (sodium stannite Na
2snO
3) compare, the free activity of removing of nanometer selenium improves 5 times, namely the activity eliminating superoxide anion and hydrogen peroxide increases substantially, sensitivity in immunological regulation and Tumor suppression also significantly increases, the high security of nanometer selenium and high bioactivity, make the health care of selenium play incisively and vividly.Recently occurred that one is named as the bacterium selenium of " Biological Selenium ", its selenium content is higher, is 1500mg/L, can be called rich selenium product, it is a kind of microbial product.Produced by fermentable, during the fermentation, zymotic fluid light yellowly becomes redness from original, and red color visible ZM bacterium motion under microscope, each thalline contains the sack of selenium as one, has inside filled red Biological Selenium, for this reason also referred to as " bio-red selenium ".By US National college library (NLM) on line data system, U.S.'s Service functions (MEDLINE) system retrieval, from 1966 so far, country more than 70,41 kinds of language, 4300 plurality of medical periodicals, more than 1,100 ten thousand, all do not find similar document or work.Therefore the new product of Ying Shi China independent development.If succeeded in developing, the height of its selenium content, will lead world standard.
Organic germanium has scavenging free radicals, strengthens the effects such as immunologic function, all can think the optimal selection of anticarcinogenic effect, and its reason is that organic germanium is by reducing the biotic potential of cell membrane to reach anticancer object.The current potential of cell membrane is high than normal cell usually, and be easy to propagation change, germanium outer-shell electron can produce Charger transfer and free radical, and free electron can capture hydrogen ion from high potential cancer cell, thus reduces cancer cell current potential, stops the breeding of cancer cell.Participate in the metabolism of oxygen in body; Organic germanium contains multiple germanium oxygen key, and the degree of combustion that can increase flue gas makes cigarette Thorough combustion reduce harm, and organic germanium simultaneously, oxidative dehydrogenation is very capable, enters human body and is combined with hemoglobin, along with blood is throughout whole body, to ensure the aerobic metabolism of cell.In addition, the oxygen in organic germanium can also combine with the hydrogen in metabolic waste, then excretes.This " oxygenation waste discharge " mechanism, is of value to the rehabilitation of the patients such as apoplexy, combined external head injuries, senile dementia.Immunity moderation function: organic germanium can induce human body cell to produce interleukins and interferon, can recover the quantity of T cell in body fluid and B cell simultaneously, improve the activity of natural killer cell (NK) and macrophage.Therefore, organic germanium has certain preventive and therapeutic effect to panimmunity deficiency disorders (various inflammation, cirrhosis, virus infections, cell infection etc.).Delay senility, promotion health is long-lived: organic germanium can improve the activity of superoxide dismutase in body (SOD) effectively, thus the active oxygen bringing out peroxide reactions is called ground state oxygen and hydrogen peroxide, hydrogen peroxide decomposes further, toxicity is removed, stop oxygen to the murder by poisoning of cell, delay the aging of cell.Remove interior free yl and peroxide.Adjustment endocrine.Have green blood spread effect, this is the reason place of adding organic germanium Ge-132 in cigarette.
Nanometer technology be the characteristic such as small-size effect, surface-interface effect, quantum size effect of applying nano materials in the production process of cigarette, to falling, spreading, spray into nano material micro mist in the material of pipe tobacco, cigarette holder, cigarette paper, and fully stir.Advantage very effectively to improve the combustibility of cigarette, improve the rejection rate to harmful substance composition in the cigarette such as nicotine, tar significantly, be conducive to reducing smoking to the harm of health, and the original local flavor of cigarette can be kept, keep the nicotine fragrance of cigarette simultaneously, meet the psychological need of smoker.
The Chemical components Component of Radix Glycyrrhizae is mainly containing flavonoids and triterpene compound.Diammonium glycyrrhizinate has the rat liver fibrosis effect of good anti-N-nitrosodimethylamine induction, and its mechanism of action may alleviate inflammation with medicine, suppresses Liver hydroxyproline to generate relevant with collagen.
Oxymatrine is the alkaloid extracted from Chinese medicine Sophora alopecuroide, has immunosupress, anti-inflammatory, antiallergy, antitumor action, and has protective effect to the hepatic injury caused by number of chemical poisonous substance.In recent years find that it has Anti-HBV activity, HCV and anti-fibrosis effect.With the Rat Liver Fibrosis Model of dimethynitrosamine amine induction, observe oxymatrine (30mg/kg, 90mg/kg) patients before and after intervention liver index, blood and hepatic tissue biochemistry, hydroxyproline content, expression of tumor necrosis factor level, Electronic Speculum and Histopathology to change.Result shows comparatively model group alanine aminotransferase, the aspartate transaminase decline of oxymatrine intervention group, and hepatic tissue hydroxyproline content and TGF-β lmRNA expression reduce (P < 0.01); Superoxide dismutase, glutathione peroxidase comparatively model group rising in intervention group hepatic tissue, and MDA is lower than model group; Electronic Speculum display stem cell injuries alleviates, and Histopathology is improved.Conclusion is that oxymatrine has Prevention and Curation effect to the liver fibrosis that N-nitrosodimethylamine is induced, and its Partial Mechanism, for protecting liver cell by anti peroxidation of lipid, suppresses fiber generation etc.
Broomrape is Orobanchaceae herbaceous plant, has the effect such as tonifying kidney and strengthening yang, ease constipation hemostasis, cures mainly impotence due to deficiency of the kidney, waist knee crymodynia, the dry constipation of intestines, functional uterine bleeding etc.Mainly be distributed in mountain area, China northeast.Be described as " not old grass " among the people, take as antidotal healthcare products.Result of study in recent years shows, broomrape has scavenging free radicals and lipoid peroxidization resistant, and can also improve the immunocompetence of Gan Kang Yin.
Sea-buckthorn is Elaeangnaceae plant, and its fruit is rich in vitamin C, Cobastab
1, folic acid and malic acid etc.Be used for the treatment of hyperlipidemia and coronary heart disease clinically.Experimental result shows, to certain density precursor, Hippophae Rhamnoides L. juice can block the chemical synthesis of N-nitrosodimethylamine significantly, suppresses the jump reaction that it causes.Result also confirms, sea-buckthorn is better than vitamin C to the blocking effect that external nitrosamine synthesizes, and may there is the bioactivator of other stopping nitrosation reactions in prompting Hippophae Rhamnoides L. juice.
Total seabuckthorn flavone, to the scavenging action of active oxygen radical, is extract the flavones ingredient obtained from Elaeangnaceae plant sea buckthorn fruit.The Mongols of sea-buckthorn system, the usual medicinal material of Tibetan, have the effects such as promoting blood circulation and removing blood stasis.Data shows that the active oxygen radical that polymorphonuclear leukocyte discharges plays an important role in the pathologic processes such as myocardial ischemia, inflammation and injury of lungs.
Cigarette smoke strengthens the protective effect of Seabuckthorn Oil to the damage of Rat Lens and selenium.Experimental result shows, in the lixiviate of smoking group rat, the content of water soluble protein, non-protein sulfhydryl and protein sulfhydryl and the activity of superoxide dismutase (SOD) and the sweet peptide peroxidase (GSH-PX) of optical valley significantly reduce, the content of water-insoluble protein and MDA (MDA) significantly raises, the These parameters then there was no significant difference of selenium strengthening Seabuckthorn Oil group.Result indicates, and cigarette smoke can cause Rat Lens damage, and selenium strengthening Seabuckthorn Oil then has protective effect.
The experimental study of Hippophae Rhamnoides L. juice antioxidation: the experimental technique taked divides two groups to after rat oral gavage 1 time with Hippophae Rhamnoides L. juice 5mL/kg and 2.5mL/kg, measures serum activity of SOD and MDA content when 30min, 1h and 2h.Result shows, with various dose Hippophae Rhamnoides L. juice to after rat oral gavage, rat blood serum SOD vigor increases MDA content and reduces, and compares, difference highly significant (P < 0.01) when the increase of 2.5mg/kg group serum activity of SOD and 1h with control group; During 5mL/kg group 30min, difference has conspicuousness (P < 0.05); The reduction by two groups of Content of MDA all when 1h difference have conspicuousness (P < 0.05), difference highly significant (P < 0.01) during 2h.More than illustrate that Hippophae Rhamnoides L. juice has oxidation resistant effect, and at short notice just can be effective, to be rich in vitamin C relevant with it for this, and visible Hippophae Rhamnoides L. juice can be used as a kind of good free radical scavenger.
Cigarette smoke strengthens the protective effect of Seabuckthorn Oil to the damage of Rat Lens and selenium, utilizes the animal model that cigarette smoke is made, and observes cigarette smoke strengthens Seabuckthorn Oil protective effect to the damage of Rat Lens and selenium.Experimental result shows, in smoking group Rat Lens, the content of water soluble protein, non-protein sulfhydryl and protein sulfhydryl and the activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) significantly reduce, the content of water-insoluble protein and MDA (MDA) significantly raises, and the These parameters of selenium strengthening Seabuckthorn Oil group is then without significant difference.Result is pointed out, and cigarette smoke can cause Rat Lens damage, and selenium strengthening Seabuckthorn Oil then has protective effect.
The experimental study of Hippophae Rhamnoides L. juice antioxidation, in order to study the antioxidation of Hippophae Rhamnoides L. juice, the experimental technique taked divides two groups to after rat oral gavage 1 time with Hippophae Rhamnoides L. juice 5mL/kg and 2.5mg/kg, when 30min, 1h and 2h, measure serum activity of SOD and MDA content.Result shows, with various dose Hippophae Rhamnoides L. juice to after rat oral gavage, rat blood serum SOD vigor increases, and MDA content reduces, compare with control group, difference highly significant (P < 0.01) when the increase of 2.5mg/kg group serum activity of SOD and 1h; During 5mL/kg group 30min, difference has conspicuousness (P < 0.05); The reduction by two groups of Content of MDA all when 1h difference have conspicuousness (P < 0.05), difference highly significant (P < 0.01) during 2h.More than illustrate that Hippophae Rhamnoides L. juice has oxidation resistant effect, and at short notice just can be effective, to be rich in vitamin C relevant with it for this, and visible Hippophae Rhamnoides L. juice can be used as a kind of good free radical scavenger.
Chinese medicine pseudo-ginseng, peach kernel, roud cardamon seed.Traditional Chinese medicine thinks that pseudo-ginseng has removing blood stasis and hemostasis, the functions such as analgesic therapy of invigorating blood circulation, and peach kernel has effect that the row stasis of blood is stimulated the menstrual flow, and roud cardamon seed has eliminating dampness to regulate the flow of vital energy, the effect of appetizing of being amusing.Pharmacological research finds that pseudo-ginseng all has regulating action to hematological system, the circulatory system etc.N-nitrosodimethylamine (DMN) can directly induced rat hepatic injury, and induces liver fibrosis, is the good derivant of liver fibrosis.Gavage with the former immersion liquid of above-mentioned Chinese medicine, observe its impact on the hepatic fibrosis rats collage synthesis that N-nitrosodimethylamine (DMN) is induced.
This research with after DMN modeling, by liver histological inspection, HE dyeing and the display of sirius red stains result: obviously, treatment by Chinese herbs group fibrosis alleviates its liver tissue fibrosis of pathology comparison group; Serological shows: pathology comparison group serum type III procollagen peptide and IV collagen are higher than Normal group (P < 0.01), treatment by Chinese herbs group type III precollagen peptide and IV collagen are all lower than pathology comparison group (P < 0.05), and hyaluronic acid change is not obvious.Therefore, show that Chinese medicine pseudo-ginseng, peach kernel, the former immersion liquid of roud cardamon seed can alleviate the rat liver fibrosis degree that DMN induces, treatment liver fibrosis is had certain effect.
Aloe can be used for treating various infantile malnutrition due to digestive disturbances or intestinalparasites malaria, eczema, rubella, tinea sore, constipation have various sterilization, antibacterial, antiviral, anti-inflammatory, anti-inflammatory, convergence, analgesic effect, contained by Fresh leaf of aloe, composition is very complicated, up to the present more than 100 kind of effective ingredient has been found that there is, good effect is had to human body, its polysaccharose substance is remarkable in the effect of raising body immunity, containing the necessary 15 seed amino acid A wide selection of colours and designs of human body.There is abundant vitamin, A
1former, B
1, B
2, B
6, B
12etc. various trace elements: the organic germanium of silicon, phosphorus, boron, copper, zinc, manganese, molybdenum, magnesium, calcium, potassium, iron, cobalt etc. tens of kinds also containing antitumaous effect, aloe is the natural drug controlling " all kinds of diseases and ailments ", has and suppresses endotoxic effect in flue gas.
Extracting obtained alcohol body lotion with Chinese herbal medicines such as the tubers of multiflower knotweed through processing in embodiment does after additive mixes with wheat is fragrant, even spraying is in the pipe tobacco surface of the pipe tobacco processes according to blended type cigarette processes, and addition is the 5%-10% (V/W) of pipe tobacco amount.Place after spraying 12-24h to liquid diffusion evenly, solvent is vaporized totally, pipe tobacco is reached roll requirement to roll.In flue gas, the test of tar and harmful substance thereof is as follows.
The assay of tar: in flue gas, tar reducing amount 10 test average out to 5.59mg/ prop up, reduced rate average out to 22.8%.And carry out trace test to depositing the sample after 2 months, show that tar reducing amount is basicly stable.
Polycyclic aromatic hydrocarbon (PAH) and benzo (α) pyrene assay: polycyclic aromatic hydrocarbon is the carcinogenic main component of tar, and wherein benzo (α) pyrene is strong carcinogenic components, so their content in tar of necessary mensuration.Measurement result: after using the Chinese herb feed additives such as the tuber of multiflower knotweed, polycyclic aromatic hydrocarbon declines.44.2%, benzo (α) pyrene declines 52.7%, all has and significantly declines.
Mouthfeel is tested: fragrance taste when cigarette burns and sucks, and must meet the national standard of blended type cigarette fragrance taste and the style had alone.The selection result of smokeing panel test is thought: the cigarette fragrance harmony of this applying liquid, and fragrance is fine and smooth, and smoke alcohol also has sweet cool feeling, and pleasant impression is pure, cigarette ash fastness is also better, have passed fragrance taste comparatively satisfactorily and closes.Additive resources of Chinese medicinal herb used is enriched, and can not strive medicine source with medical treatment.Provide the foundation for applying of Chinese herb feed additive again.
The toxicity test of flue gas: select Kunming mouse 80, divides 4 groups and carries out long term toxicity test.Result draws: sample cigarette has no side effect, and long-term taking sample cigarette is obviously better than control group.As smoked twice group every day, inhaling sample cigarette Mouse Weight increases higher than control group; On the contrary, the transaminase values of sample cigarette mouse is inhaled but lower than control group.
The discussion of the mechanism of action: tentatively think that this kind of Chinese herb feed additive has combustion-supporting suction-operated, and make the harmful substance contents such as tar, BaP in cigarette gas lower.
Adopt natural galenical, the mutagenesis of AML-1 external suppression benzo (α) pyrene.Said preparation selects the multiple natural plant formula Hydrolysis kinetics such as mulberry leaf, Su Ye, cacumen biotae to form.Result of the test shows that the mutagenesis of natural galenical to strong carcinogen benzo (α) pyrene has very strong inhibitory action.
Apply that traditional chinese medicine " is used as medicine with lung ", the principle of " fumigation and steaming therapy ".With containing the 0.5% original liquid concentrated through the refining of modern pharmaceutical technology by Chinese herbal medicines such as barrenwort, the root of herbaceous peony, thizoma curculiginis, the Radix Astragali, radix bupleuri in cigarette.In cigarette, icariin average content 3.06 μ g/ props up, and the rate of transform is 25.5%; Paeoniflorin average content 9.23 μ g/ props up, and the rate of transform is 20.2%.Result shows: compared with blank cigarette, and in cigarette mainstream flue gas, benzo (α) pyrene reduces 21.8%, and in flue gas, unique nitrosamine reduces 26.3%, and wherein NNN reduces 33.1%.Animal toxicity experiment shows, cigarette has reduction cigarette teratogenesis, mutagenesis and carcinogenesis; The degree of injury of mouse kidney, heart and Sperm specific enzyme is obviously reduced; There is antagonism to immune function of mice and suppression, the cellular immune level of body can be improved, have reducing effect to the arteriosclerotic some factors of formation.Qualification is thought, this project, to development " Chinese-style cigarette ", promotes reducing tar and reducing harm work and has positive role.Measure in the effective ingredient rate of transform, reduce benzo (α) pyrene and TSNA in cigarette smoke, the research of anti-" three cause " test and crowd's viewing test aspect has certain novelty.And for example embodiment 5 utilizes Radix Glycyrrhizae, the fruit of Chinese magnoliavine, wrinkled giant hyssop, dalbergia wood as the research of cigarette additive, and result shows, they can effectively reduce flue gas free radical, thus reduces the toxicity of cigarette.
The preparation method of extracts of Chinese herbal medicine takes Radix Glycyrrhizae, the fruit of Chinese magnoliavine, wrinkled giant hyssop, each 5g of dalbergia wood respectively, and get 24h with 100mL95% alcohol steep, filtering and concentrating is to 25mL.The preparation process of drug cigarette takes pipe tobacco 30g respectively, evenly sprayed as a control group by above-mentioned various extracts of Chinese herbal medicine 10mL95% ethanol.
The peak intensity reduced rate of cigarette additive to gaseous phase free radical made by Radix Glycyrrhizae, the fruit of Chinese magnoliavine, wrinkled giant hyssop, dalbergia wood extract.Result can be found out, this several Chinese herbal medicine all possesses certain Scavenging activity as cigarette additive to cigarette smoke phase free radical, and wherein reduce effect with wrinkled giant hyssop and fruit of Chinese magnoliavine additive to Free Radicals In Cigarette Smoke more obvious, Radix Glycyrrhizae and dalbergia wood take second place.Research finds, also can produce and discharge a kind of endotoxic material, threaten to human health after cigarette burning.
Endotoxin is a kind of toxin being produced by some specific bacteria and discharge when this bacterium is fissioned.In indoor environment, if endotoxin concns is lower, then also little to the harm of health.But along with its concentration raises, also increasing to the harm of health, may a series of diseases such as respiratory inflammation be caused.
Smoking can cause the endotoxin concns in particular space to rise.Quantitatively accurate to this has been by smoking-simulating situation under study for action, the endotoxin concns recorded in house common between after smoking is up to 120 times before smoking.
Discharge the endotoxin removed after result of combustion of tobacco, the bacterium lived in before being probably in tobacco produced.Be likely that a lot of smoker suffers from the reason of breathing problem.
The current research display of Lund, Sweden university scientific man, containing causing asthma and bronchitic endotoxin in a large number in the smog that smoker breathes out, this material can have a strong impact on the respiratory health of involuntary smoker.
It is reported, Sweden scientist proves to be generated by bacterium first, and the endotoxin of Lock-in in atmosphere also can be out manufactured under the tobacco product smoky environment of high concentration: in the room filled the air, and endotoxin concns is more than 120 times of smokeless indoor.This discovery will make people definitely in the necessity of the public place ban on opium-smoking and the opium trade closed.
When endotoxin concns is very high, it can cause serious inflammation in respiratory tract, thus causes bronchitis and asthma.Research also shows, and the endotoxin produced under smoky environment is one maximum to human body side effect in all endotoxins.Researcher claims, and perhaps this is exactly smoker's often one of reason suffering from respiratory disorder.Researcher never finds that cigarette smoke is really containing endotoxin bacteria lipopolysaccharide before this.
Containing more than 5000 kinds of chemical compositions in tobacco, wherein have 50 kinds and be proved to be and can cause cancer.
Embodiment 6 utilizes removing and the deactivation of the induced by endotoxins such as Chinese medicine Cordyceps sinensis, and Effect of Chinese Medicine Qing is except endotoxin is mainly through following 3 kinds of approach: 1. strengthen body detoxication mechanisms, mainly help recuperating depleted yang class, as ginseng, the Radix Astragali etc.2. directly deactivation is detoxified or is reduced its toxicity, and medicine mostly is antipyretic and antidotal type, as honeysuckle, the capsule of weeping forsythia, the coptis, folium isatidis, cordate houttuynia, chrysanthemum, Radix Isatidis, dandelion, the root of large-flowered skullcap, sweet wormwood etc.; 3. strengthen body and drain endotoxic ability, be mainly logical internal organs and rush down lower class, as the compound preparation of rheum officinale and composition thereof.
In the processing procedure of pipe tobacco, fall in pipe tobacco, spread, spray into nano material particulate powder, and fully stir.Advantage very effectively to improve the combustibility of cigarette, improve the rejection rate to harmful substance composition in the cigarette such as nicotine, tar significantly, be conducive to reducing smoking to the harm of health, and the original local flavor of cigarette can be kept, keep the nicotine fragrance of cigarette simultaneously, meet the physiological requirement of smoker.
By nano material Al
2o
3, SiO
2, TiO
2join in cigarette shreds and filter tip, the four kinds of feed postition that have studied nano material on cigarette smoke grain mutually in tar, nicotine one-tenth amount impact.Result shows: (1) nano material dry filtration mouth, reduces tar in flue gas, nicotine effect is the most obvious.Accurately take a certain amount of (0.0,2.0,4.0,6.0,8.0,10.0mg/ props up) three kinds of different nano material (Al
2o
3, SiO
2, TiO
2), get involved in the filter tip of commercially available finished cigarettes, the sample cigarette in " sandwich " shape composite filter tip.
Nano material dry method add cigarette filter all can significantly reduce tar in flue gas, nicotine generate, with above-mentioned three kinds of nano materials and different amounts basically identical to tar, nicotine impact variation tendency.Dry method adds in filter tip, and nano material does not participate in the forming process of flue gas, mainly plays absorption crown_interception to flue gas, and the similar specific surface of three kinds of nano materials, and therefore they are basically identical to the effect tendency of tarry matters in smoke, nicotine.Namely, along with the increase of nano material addition, except the suction-operated of itself, filter tip resistance to suction also can be caused to increase.Resistance to suction increases also can make the retain efficiency of filter tip to tarry matters in smoke, nicotine increase.When nano material addition reach 10.0mg/ prop up time, reduce tarry matters in smoke amount 7.77mg/ and prop up, reducing tar rate reaches 45.3%; Reduce flue gas nicotine content 0.33mg/ to prop up, reduced rate is 28.4%.(2) nano material dry method adds pipe tobacco, and effect is comparatively remarkable, adds the nano material (Al that 5.0-25.0mg/ props up
2o
3, SiO
2, TiO
2), reducing tar 4.2%-32.2%, reduces nicotine 2.4%-20.3%, wherein nanometer Al
2o
3action effect remarkable.(3) nano material wet method is added in pipe tobacco, DeGrain; Wet method joins in cigarette filter tow, does not almost have effect.Nano material Al
2o
3, SiO
2, TiO
2, specific area 640m
2/ g, by Chinese Academy of Sciences's solid-state physics Research Institute.In addition, by Application of micron in cigarette, estimate every large case (50000) cigarette, increase cost about 20 yuans, thus there is larger application prospect.
Nanometer powder is added in filter tip, to reduce the tar content in flue gas.The preparation of nanometer powder: adopt gas phase hydrolysis method, hydro-thermal method and microwave heating method to synthesize nano-oxide series, nano-silicon aluminate serial, nanometer sodalite, Nano-meter CaCO3 respectively
3with samples such as 4A, NaY, NaX, H β nano molecular sieves.Prepared nanometer powder is non-volatility, tasteless white powder, and particle diameter is at 25-110nm.The smaller the better.
Chitin is a kind of natural resources that on the earth, storage is very abundant, is also the uniquely positively charged tunicin that occurring in nature is found up to now.Due in its molecular structure with undersaturated cation group, thus to all kinds of harmful substances with negative electrical charge, there is powerful suction-operated.Equally, it also can know the rubbish in human body, the object of reach prevent disease, promoting longevity.Chitin is a kind of natural biological high polymer extracted from the cell membrane of the shell of shell, shrimp, crab, insect and mushroom, algae, at nature, the year biosynthesis amount of chitin more than about 1,000 hundred million tons is the organic regenerative resource of the i.e. horn of plenty being only second to cellulose reserves.
Chitin also known as chitin, chitin and tobacco used in combination time, the highest consumption of chitin is 75%, and, and in this scope combustion, gustation and smell are all more satisfactory between 10%-35% better.This is because chitin (is analyzed through GC/MC at about 900 DEG C formation Pyrazine aromatic compositions in result of combustion of tobacco process, obtain 2-ethyl-3-Methyl-pyrazin compound), and the harmful components such as nicotine, tar can be reduced, the most important derivative shitosan of chitin.The principle of tar and other harmful substances in cigarette smoke removed by shitosan, general cigarette filter is made up of cellulose silk or non-woven fabrics, only play general filtration, namely the minute solid particles (aerosol) in flue gas is stopped, very poor to atomic little aerosol filtration.Adding the composite filter tip that active carbon makes in filter-tip material is physisorption.And the harmful components in shitosan absorption flue gas show as two kinds of citation forms: intermolecular physical absorption and chemisorbed.Intermolecular physical absorption refer in neutral organic and inorganic molecule by intermolecular Van der Waals force by shitosan macromolecules adsorption on cancellated skeleton; Harmful substance in flue gas is all have polarity as ammonia, carbon monoxide, is easy to the macromolecular-NH with shitosan
2group or-OH group form intermolecular Hydrogenbond or chelating and ion and electrically adsorb i.e. chemisorption.
Conclusion: 1. shitosan optionally can adsorb harmful components in flue gas as carbon monoxide, tar; 2. tar content can also regulate the methods such as the content of shitosan in composite filter tip to regulate according to the needs of the different consumer groups; 3. chitosan absorbent due to its molecular structure special, make it have removal effect to the harmful components in tobacco, have wide range of applications, nontoxic, be beneficial to environmental protection, can not secondary pollution be caused, promising.In addition, the result of study of Wang Xiaokui etc. [Light Engineering Institutes Of Zhengzhou journal natural science edition .2002 (2): 104-107] shows, the chitosan solution of the deacetylation 90% of 1.0mL is added in cigarette, in main flume, tar reduces by 15.5%, nicotine reduces by 13.8%, and interior quality is significantly improved.
Use China's Chinese Traditional Medicine theory, combine modern advanced extracting and developing technology, nanometer technology, develop a kind of novel plant extract---nano powder being applied to cigarette industry, and it is successfully applied in the pipe tobacco of cigarette and the cigarette paper of cigarette.To having heat-clearing, relieving asthma, the Chinese herbal medicine of cough-relieving and anti-mutagenesis and radicals scavenging function screens, wherein have the Chinese medical extract nano powders such as chrysanthemum, honeysuckle, folium isatidis, Herba Andrographitis, ginkgo leaf, carrotene, the root of large-flowered skullcap, ursolic acid.
Cigarette additive, its main component also has the material of the multiple beneficial healths such as Chloranthus glaber, general coumarin and polyphenol compound.The boiling point of its active ingredient is 150-280 DEG C, and easily gasification enters respiratory tract with flue gas.Fully can coordinate with pipe tobacco in color, smell and taste, after inhaling, pleasant impression is comfortable, has and significantly returns sweet taste.Be added in cigarette, measure the transfer conveying capacity of active ingredient and the rate of transform, measurement result shows, the transfer conveying capacity of active ingredient reaches 5 μ g/ and props up left and right, and the rate of transform reaches more than 28%.HPLC method is utilized to carry out analyzing measuring to active ingredient general coumarin in cigarette shreds and cigarette smoke, result shows: the content of cigarette shreds general coumarin is that 18.55 μ g/ prop up, in cigarette smoke, the content of general coumarin is that 5.22 μ g/ prop up, and the rate of transform is 28.14%.
The harmfulness of cigarette is carried out to the biological assessment of system.Result of study shows, Chinese medical extract nano powder has obvious blocking effect to volatile nitrosamine and tobacco-specific nitrosamine synthesis, significant inhibitory action is had to the mutagenicity of benzo (α) pyrene, animal and cell assay in vitro all do not observe toxic action, show plant extracts safety non-toxic.On this basis, to plant get thing be applied to cigarette product and reduce cigarette harm effect be studied.Smoke chemistry analysis and biological evaluation result show, compare with the cigarette that contrasts not adding plant extracts, significantly can alleviate the bad reactions such as caused by smoking cough, asthma, stasis of blood phlegm, obviously reduce the incidence of disease of respiratory tract; Free Radical Level reduces more than 20%; The acute toxic reaction of mouse obviously alleviates, and shows as the prolonged survival period 1 times of animal.
Pine extract is composite type antioxidant (anti-ageing) material of the best found up to now in the world! Pine tree preparation is the most potent free radical scavenger found up to now, its Green Tea Extract oxidability is 60 times of vitamin E, is ascorbic 20 times, and absorption in human body is complete rapidly, within oral 20 minutes, can reach the highest haemoconcentration, metabolic half life is for 7 hours.
The flavones extracted from pine tree and PCA not in human body antioxidation activity be higher than vitamin E.In human body low-density lipoprotein, cholesterol oxidation and be cause vascular atherosclerosis and cardiopathic key factor in the deposition of vascular wall.Human vascular is the vitals transporting oxygen and nutriment, and blood must keep clean state.
The bioflavonoids extracted from pine tree has anticoagulation, can improve blood fluidity, the toughness of protection blood vessel and elasticity, and tissue cholesterol is at Ink vessel transfusing abnormal deposition, and protection cardiovascular and cerebrovascular, reduces cardiovascular and cerebrovascular disease to the threat of human body.Bioflavonoids can also participate in human body collagen and elastin laminin combines, and collagen and elastin laminin form the main component of skin just.Bioflavonoids can enter capillary in human body, protection microcirculqtory system, scavenging free radicals.The effect of bioflavonoid directly can reach skin surface, improves skin quality.
Extract from pine needles is rich in carbohydrate, crude protein, crude fat, several amino acids and lot of trace mineral element, multivitamin, antibiotic, bioflavonoid material, ferment, essential oil, chlorophyll, unrighted acid, enzyme and coenzyme isoreactivity material, also for expansion artery blood vessel, increase red blood cell oxygen carrying capacity, stimulate circulation, improve the function of capillary, improve immunity, increase the secretion of hormone, what make health organizes rejuvenation.
Zeolite is that in the middle of nature, minority is with one of the mineral matter of negative electrical charge, and mainly with the heavy metal with positive electricity in many bodies, blood poison, intestines are malicious, lymph is malicious, cell toxicant and free radical have strong suction-operated.Zeolite absorption Radiochemicals and other harmful toxins is all utilized in the young nuclear leakage event of Russia, the U.S. and Japan.Montmorillonite has monoclinic crystal structure, belong to 2: 1 type layered clay minerals, each crystal layer is made up of two-layer silicon-oxy tetrahedron therebetween one deck alumina octahedral, there is good adsorptivity, ion exchangeable and volumetric expansion, can be acted on by absorption, ion-exchange, coagulation etc. in aqueous and pollute without having an effect, finally reach the object removing pollutant.In adsorption-decomposition function flue gas, the toxicity of benzo (α) pyrene in polycyclic aromatic hydrocarbon and fluorescence anthracene etc. is eliminated in the effect of nitrosamine effectively.
Sepiolite is a kind of magnesia silicate of porous of fibre morphology, its electrical chemical formula Mg
8si
12o
30(OH)
4(OH
2)
48H
2o, but its composition alters a great deal with the difference in the place of production.In its construction unit, silicon-oxy tetrahedron and magnesia octahedron alternate, and have the transiens feature of stratiform and chain.Just because of the structure of this uniqueness, such that sepiolite specific area is high, porosity is large, and surface acidity is weak, passage is little, and heat endurance is bad, and these weakness limit the application of sepiolite, thus in advance through process such as purification, processing, modifications, its performance must be improved further.
The activation method of sepiolite comprises surperficial modification, high-temperature calcination, high energy radiation, soda acid process, catalyst remodeling and combination process process etc., comparatively conventional to heat with acid treatment.Sepiolite is heated to 100-150 DEG C, and the adsorbed water in removing sepiolite hole, can increase its specific area; With pickling sepiolite, remove the impurity such as the carbonate in hole, can pore volume be increased.
Cigarette smoke is made up of a large amount of small particle of diameter 0.1-1 μm and gaseous substance: make filter tip with diacetate fiber, can retain the small particle in flue gas, and retain seldom to pernicious gas; Make filter tip with active carbon, because its specific area is huge, can adsorb to non-selectivity the gas in flue gas in a large number, and make cigarette become tasteless.Make cigarette filter material with sepiolite, not only can retain the small particle in flue gas, and significantly selective to being adsorbed with of flue gas.
In order to increase the quantity of electric charge on montmorillonite surface, improve adsorption capacity, the bentonite after activation adds the inorganic additive of about 2%, reacts, thus retrofited under uniform temperature, time.
Because montmorillonite adopts acid activation remodeling in processing, make SiO
2and TiO
2content increases, and Al
2o
3, MgO, CaO, K
2o content all reduces, and increases the free space of montmorillonite character inside, specific area and a large amount of micropore, makes it have larger adsorption capacity, also increase be with negative electrical charge quantity simultaneously.
In montmorillonite absorption cigarette smoke, the effect of tar, shows as two kinds of forms: the physical absorption of molecule and chemisorbed (the electrical absorption of ion).In cigarette smoke, harmful substance is all polar compound, and it more easily electrically adsorbs with the montmorillonite generation ion with negative electrical charge.Make cigarette filter with montmorillonite, not only can retain the small particle in flue gas, and have the absorption of flue gas significantly selective.As it is to the polar gas compound Preferential adsorption be harmful to health, and to non-polar compound absorption seldom, and these non-polar compounds can make the cigarette taste of cigarette denseer.
Montmorillonite is after suitably processing, remodeling, the granule adsorbent made, be used on cigarette composite filter tip, to tar in cigarette smoke, there is obvious suction-operated, to the free radical in tar, also there is obvious suction-operated, but less to the nicotine absorption in cigarette, make that cigarette smoke is pure, no impurity taste, nontoxic, cost is low, be applicable to China smoker taste, can promote the use of.
The filter effect of TPM in flue gas, measurement result draws, the filter effect of medical stone is best, and the filter efficiency in Jin Zhong and the Silk Road reaches 32.9% and 33.7% respectively; Next is that the expanded vermiculite of 50% medical stone+30% purification bentonite+20% reaches 32.6% and 31.0% respectively; Purification bentonite, active carbon take second place; Expanded vermiculite effect is the poorest.Significance test of difference result, with CK
2, the filter effect of medical stone reaches the level of signifiance, although bentonitic filter effect of purifying is also higher than CK
2, but not reaching the level of signifiance, all the other several samples are then lower than CK
2.
Different sorbing material filter tip is to the filter effect of tar in flue gas: 50% medical stone, the expanded vermiculite of 30% purification bentonite+20%; Purification bentonite filter effect is higher, and expanded vermiculite is the poorest.Significance test of difference result shows, filter effect and CK
2compare and reach the level of signifiance, with more than CK
2, but not reaching the level of signifiance, all the other are then lower than CK
2.
Different sorbing material filter tip is to the filter effect of smoking nicotine, and measurement result shows, the filter effect of different sorbing material to the smoking nicotine in 2 kinds of filter tip cigarettes has different.Gold clock cigarette is the highest with fine perlite filter effect, and filter effect reaches 45.4%, CK
2(active carbon) is minimum, filter effect E=31%.It is the highest that Silk Road cigarette then shows as purification bentonite filter effect, is 42.6%, and filter effect is minimum, is only 28.8%.Significance of difference result shows, all reaches the level of signifiance.
Brief summary: result of the test shows, uses the composite filter tip containing variable grain sorbing material to the filter effect Comprehensive Correlation of smoke's total particulate matter, tar, flue gas, nicotine content, best with Medical stone filtering effect.This illustrates, in medical stone, main mine material is if potassic feldspar, biotite, hornblend etc. are to the dominant active carbon that is better than of the adsorptivity of the harmful components in flue gas, and secondly general performance is preferably purification bentonite.
Different sources schorl chemical composition and polarization characterization of adsorption thereof are analyzed, has prepared the tourmaline composite micropore suction strainer agent being applied to cigarette " reducing tar and reducing harm ", visual test " reducing tar and reducing harm " effect of suction strainer agent simultaneously.Experimental result shows: the agent of tourmaline composite micropore suction strainer has good suction-operated to the tar in cigarette smoke and harmful components thereof, initial analysis " falling Jiao to remove the evil " mechanism of tourmaline suction strainer agent.
5 kinds of sorbing materials such as active carbon are to the filter effect of mascot total in cigarette smoke, measurement result draws, the filter effect of medical stone is best, the filter effect of tar in flue gas is shown, use the composite filter tip containing variable grain sorbing material to the filter effect Comprehensive Correlation of smoke's total particulate matter, tar, flue gas, nicotine content, best with Medical stone filtering effect.This illustrates, in medical stone, main mine material is if potassic feldspar, biotite, hornblend etc. are to the dominant active carbon that is better than of the adsorptivity of the harmful components in flue gas, and secondly general performance is preferably purification bentonite.
Medical stone has absorption antagonism except malicious harm reduction to heavy metal in flue gas harmful element, and can discharge the various trace elements useful to human body.Tourmaline is a kind of natural negative ion generating material of spontaneous continuous generation anion fine-purification air, tourmaline chemical composition and polarization characterization of adsorption thereof are analyzed, prepared the tourmaline composite micropore suction strainer agent being applied to cigarette " reducing tar and reducing harm ", visual test " reducing tar and reducing harm " effect of suction strainer agent simultaneously.Experimental result shows: the agent of tourmaline composite micropore suction strainer has good suction-operated to the tar in cigarette smoke and harmful components thereof, and " falling Jiao to remove the evil " effect obviously.
Below in conjunction with embodiment, the present invention is further described
Specific implementation method:
Embodiment 1:
(1) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: become by the anti-spy of pine tree zeolite and suppress the anticancer nicotine-free non-tar cigarette of nitrosamine, by following masses proportioning composition %
(2) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: filter poison by pine needle medical stone and reduce damage by fume freeradical nicotine nicotine-free non-tar cigarette, by following masses proportioning composition %
(3) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: by arbor-vitae sepiolite except damage by fume tar suppresses BaP nicotine-free non-tar cigarette, by following masses proportioning composition %
(4) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: by arbor-vitae sepiolite except damage by fume tar suppresses BaP nicotine-free non-tar cigarette, by following masses proportioning composition %
(5) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: by the anticancer nicotine-free non-tar cigarette of the anti-polycyclic aromatic hydrocarbon of Japanese red pine tourmaline decoking harm reduction, by following masses proportioning composition %
(6) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: by masson pine montmorillonite tar removing freeradical BaP cigarette poison nicotine-free non-tar cigarette, by following masses proportioning composition %
(7) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: by the clear flue gas damage by fume nitrosamine endotoxin nicotine-free non-tar cigarette of rich selenium germanium Pine plants remedies series, by following masses proportioning composition %
A kind of rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, become by the anti-spy of pine tree zeolite and suppress the anticancer nicotine-free non-tar cigarette of nitrosamine, pine needle medical stone filter poison reduces damage by fume freeradical nicotine nicotine-free non-tar cigarette, arbor-vitae sepiolite is except damage by fume tar suppression BaP nicotine-free non-tar cigarette, the anticancer nicotine-free non-tar cigarette of the anti-polycyclic aromatic hydrocarbon of Japanese red pine tourmaline decoking harm reduction, masson pine montmorillonite tar removing freeradical BaP cigarette poison nicotine-free non-tar cigarette, Korean pine opal removes carbon monoxide nitric oxide endotoxin nicotine-free non-tar cigarette, the clear flue gas damage by fume nitrosamine endotoxin nicotine-free non-tar cigarette composition of rich selenium germanium Pine plants remedies series, it is characterized in that: form % by following masses proportioning
Embodiment 2: a kind of rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, become by the anti-spy of pine tree zeolite and suppress the anticancer nicotine-free non-tar cigarette of nitrosamine, pine needle medical stone filter poison reduces damage by fume freeradical nicotine nicotine-free non-tar cigarette, arbor-vitae sepiolite is except damage by fume tar suppression BaP nicotine-free non-tar cigarette, the anticancer nicotine-free non-tar cigarette of the anti-polycyclic aromatic hydrocarbon of Japanese red pine tourmaline decoking harm reduction, masson pine montmorillonite tar removing freeradical BaP cigarette poison nicotine-free non-tar cigarette, Korean pine opal removes carbon monoxide nitric oxide endotoxin nicotine-free non-tar cigarette, the clear flue gas damage by fume nitrosamine endotoxin nicotine-free non-tar cigarette composition of rich selenium germanium Pine plants remedies series, it is characterized in that: form % by following masses proportioning
Embodiment 3: a kind of rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, become by the anti-spy of pine tree zeolite and suppress the anticancer nicotine-free non-tar cigarette of nitrosamine, pine needle medical stone filter poison reduces damage by fume freeradical nicotine nicotine-free non-tar cigarette, arbor-vitae sepiolite is except damage by fume tar suppression BaP nicotine-free non-tar cigarette, the anticancer nicotine-free non-tar cigarette of the anti-polycyclic aromatic hydrocarbon of Japanese red pine tourmaline decoking harm reduction, masson pine montmorillonite tar removing freeradical BaP cigarette poison nicotine-free non-tar cigarette, Korean pine opal removes carbon monoxide nitric oxide endotoxin nicotine-free non-tar cigarette, the clear flue gas damage by fume nitrosamine endotoxin nicotine-free non-tar cigarette composition of rich selenium germanium Pine plants remedies series, it is characterized in that: form % by following masses proportioning
Embodiment 4: a kind of rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, become by the anti-spy of pine tree zeolite and suppress the anticancer nicotine-free non-tar cigarette of nitrosamine, pine needle medical stone filter poison reduces damage by fume freeradical nicotine nicotine-free non-tar cigarette, arbor-vitae sepiolite is except damage by fume tar suppression BaP nicotine-free non-tar cigarette, the anticancer nicotine-free non-tar cigarette of the anti-polycyclic aromatic hydrocarbon of Japanese red pine tourmaline decoking harm reduction, masson pine montmorillonite tar removing freeradical BaP cigarette poison nicotine-free non-tar cigarette, Korean pine opal removes carbon monoxide nitric oxide endotoxin nicotine-free non-tar cigarette, the clear flue gas damage by fume nitrosamine endotoxin nicotine-free non-tar cigarette composition of rich selenium germanium Pine plants remedies series, it is characterized in that: form % by following masses proportioning
Embodiment 5: a kind of rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, become by the anti-spy of pine tree zeolite and suppress the anticancer nicotine-free non-tar cigarette of nitrosamine, pine needle medical stone filter poison reduces damage by fume freeradical nicotine nicotine-free non-tar cigarette, arbor-vitae sepiolite is except damage by fume tar suppression BaP nicotine-free non-tar cigarette, the anticancer nicotine-free non-tar cigarette of the anti-polycyclic aromatic hydrocarbon of Japanese red pine tourmaline decoking harm reduction, masson pine montmorillonite tar removing freeradical BaP cigarette poison nicotine-free non-tar cigarette, Korean pine opal removes carbon monoxide nitric oxide endotoxin nicotine-free non-tar cigarette, the clear flue gas damage by fume nitrosamine endotoxin nicotine-free non-tar cigarette composition of rich selenium germanium Pine plants remedies series, it is characterized in that: form % by following masses proportioning
Embodiment 6: a kind of rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, become by the anti-spy of pine tree zeolite and suppress the anticancer nicotine-free non-tar cigarette of nitrosamine, pine needle medical stone filter poison reduces damage by fume freeradical nicotine nicotine-free non-tar cigarette, arbor-vitae sepiolite is except damage by fume tar suppression BaP nicotine-free non-tar cigarette, the anticancer nicotine-free non-tar cigarette of the anti-polycyclic aromatic hydrocarbon of Japanese red pine tourmaline decoking harm reduction, masson pine montmorillonite tar removing freeradical BaP cigarette poison nicotine-free non-tar cigarette, Korean pine opal removes carbon monoxide nitric oxide endotoxin nicotine-free non-tar cigarette, the clear flue gas damage by fume nitrosamine endotoxin nicotine-free non-tar cigarette composition of rich selenium germanium Pine plants remedies series, it is characterized in that: form % by following masses proportioning
Embodiment 7: a kind of rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, become by the anti-spy of pine tree zeolite and suppress the anticancer nicotine-free non-tar cigarette of nitrosamine, pine needle medical stone filter poison reduces damage by fume freeradical nicotine nicotine-free non-tar cigarette, arbor-vitae sepiolite is except damage by fume tar suppression BaP nicotine-free non-tar cigarette, the anticancer nicotine-free non-tar cigarette of the anti-polycyclic aromatic hydrocarbon of Japanese red pine tourmaline decoking harm reduction, masson pine montmorillonite tar removing freeradical BaP cigarette poison nicotine-free non-tar cigarette, Korean pine opal removes carbon monoxide nitric oxide endotoxin nicotine-free non-tar cigarette, the clear flue gas damage by fume nitrosamine endotoxin nicotine-free non-tar cigarette composition of rich selenium germanium Pine plants remedies series, it is characterized in that: form % by following masses proportioning
Claims (1)
1. a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: form % by following masses proportioning
(1) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: become by the anti-spy of pine tree zeolite and suppress the anticancer nicotine-free non-tar cigarette of nitrosamine, by following masses proportioning composition %
(2) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: filter poison by pine needle medical stone and reduce damage by fume freeradical nicotine nicotine-free non-tar cigarette, by following masses proportioning composition %
(3) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: by arbor-vitae sepiolite except damage by fume tar suppresses BaP nicotine-free non-tar cigarette, by following masses proportioning composition %
(4) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: by arbor-vitae sepiolite except damage by fume tar suppresses BaP nicotine-free non-tar cigarette, by following masses proportioning composition %
(5) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: by the anticancer nicotine-free non-tar cigarette of the anti-polycyclic aromatic hydrocarbon of Japanese red pine tourmaline decoking harm reduction, by following masses proportioning composition %
(6) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: by masson pine montmorillonite tar removing freeradical BaP cigarette poison nicotine-free non-tar cigarette, by following masses proportioning composition %
(7) a rich selenium germanium nanometer plant remedies nicotine-free non-tar cigarette, is characterized in that: by the clear flue gas damage by fume nitrosamine endotoxin nicotine-free non-tar cigarette of rich selenium germanium Pine plants remedies series, by following masses proportioning composition %
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050039765A1 (en) * | 2003-08-22 | 2005-02-24 | Philip Morris Usa, Inc. | Method for dispersing powder materials in a cigarette rod |
| US8281793B2 (en) * | 2003-10-27 | 2012-10-09 | Philip Morris Usa Inc. | Formation and deposition of sputtered nanoscale particles in cigarette manufacture |
| CN103892461A (en) * | 2014-03-22 | 2014-07-02 | 南通蛇类治疗研究所 | Selenium-germanium rich composite zeolite group poison-filtering cigarette tip |
| CN103932386A (en) * | 2014-03-22 | 2014-07-23 | 南通蛇类治疗研究所 | Selenium enrichment plant low-harm element cigarette |
-
2015
- 2015-02-13 CN CN201510084342.0A patent/CN104770862A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050039765A1 (en) * | 2003-08-22 | 2005-02-24 | Philip Morris Usa, Inc. | Method for dispersing powder materials in a cigarette rod |
| US8281793B2 (en) * | 2003-10-27 | 2012-10-09 | Philip Morris Usa Inc. | Formation and deposition of sputtered nanoscale particles in cigarette manufacture |
| CN103892461A (en) * | 2014-03-22 | 2014-07-02 | 南通蛇类治疗研究所 | Selenium-germanium rich composite zeolite group poison-filtering cigarette tip |
| CN103932386A (en) * | 2014-03-22 | 2014-07-23 | 南通蛇类治疗研究所 | Selenium enrichment plant low-harm element cigarette |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105559134A (en) * | 2015-11-09 | 2016-05-11 | 南通蛇类治疗研究所 | Cigarette additive containing natural medicines and stones, nano-elements and negative ions |
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