CN104750132B - A kind of test temperature bearing calibration, controller and test temperature correction system - Google Patents
A kind of test temperature bearing calibration, controller and test temperature correction system Download PDFInfo
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Abstract
The invention discloses a kind of test temperature bearing calibration, controller and test temperature correction system, detection conversion zone temperature, first threshold is heated to when the temperature of detection is less than first threshold to be tested, obtain target detection result, test is directly carried out when the temperature of detection is first threshold and obtains desired value, when the temperature of detection is carried out obtaining desired value corresponding to the correction of the temperature to the value that test is obtained higher than first threshold and during less than Second Threshold, can be tested in the case of different temperatures, carry out temperature adjustment or test result correction to obtain accurate test result according to current conversion zone temperature and threshold temperature relation, test equipment is required without constant temperature substantially, accurate test result can be obtained by relatively low cost, improve accuracy and the efficiency of test.
Description
Technical field
The present invention relates to biomedical field tests, more particularly to a kind of test temperature bearing calibration, controller and survey
Examination temperature correction system.
Background technology
Some biomedicine tests, such as during microdose urine protein testing, temperature has very big shadow to test result
Ring.
Currently the majority microdose urine protein testing adopts immunoturbidimetry, and which adopts large-scale biochemical instruments equipment test, its
Biochemical instruments constant temperature is needed just to ensure the accuracy of test result at a certain temperature, when ambient temperature is less than specified test temperature
Test temperature can be lifted by lower-cost mode of heating, and it is also simpler to increase heater in a test device
Single, the structure influence to test device is less；But when ambient temperature is higher than specified test temperature, substantially can not with existing means
Cooling purpose can be reached on the premise of test device structure is not changed as far as possible, it is necessary to use thermostatic equipment with high costs, because
This existing test device is had high demands to instrument constant temperature when wanting to obtain accurate test result, if without thermostat, in temperature
Spend inconstant situation to be tested exactly.
Content of the invention
In view of this, present invention is primarily targeted at providing a kind of test temperature bearing calibration, controller and test temperature
Degree correction system, can ensure the accuracy of test result under different temperatures environment by relatively low cost.
For achieving the above object, the invention provides a kind of test temperature bearing calibration, including：
Detection conversion zone temperature；
When the conversion zone temperature is less than first threshold temperature, start behind reacting by heating region to first threshold temperature
The test of preset content, using test value as desired value；
When the conversion zone temperature is first threshold temperature, directly starts the test of preset content, test value is made
For desired value；
When the conversion zone temperature is higher than first threshold temperature and less than Second Threshold temperature, directly start in default
The test of appearance, after obtaining test value, obtains corresponding correction function according to conversion zone temperature, using the correction function to surveying
Examination value is corrected and obtains desired value.
Preferably, obtaining corresponding correction function according to conversion zone temperature includes：
Correction function set is obtained, included in the selection correction function set is closest with current conversion zone temperature
Temperature value, corresponding for temperature value correction function is defined as the corresponding correction function of current conversion zone temperature.
Preferably, the correction function is the linear relationship function for including the first correction coefficient and the second correction coefficient.
Preferably, obtaining correction function set includes：
Determine each experimental concentration value of the first preset number；
Determine each experimental temperature value higher than first threshold temperature and the second preset number less than Second Threshold temperature；
Carry out the test of the preset content of each experimental concentration when conversion zone temperature is each experimental temperature value respectively, obtain
Each experiment test value corresponding with each experimental concentration under every kind of experimental temperature value；
Conversion zone temperature be first threshold at a temperature of carry out each experimental concentration preset content test, obtain with respectively
Experimental concentration is corresponding each with reference to test value；
Conversion zone concentration is worth to for every kind of experiment with reference to test value and experiment test according to each experimental concentration is corresponding
During temperature value, first correction of the corresponding experiment test value with conversion zone temperature for the reference test value of first threshold temperature is
Number and the second correction coefficient；
The first correction coefficient according to every kind of experimental temperature value obtains corresponding correction function with the second correction coefficient.
Present invention also offers a kind of controller, is applied to test temperature correction, the controller includes：
Judge module, for judging the conversion zone temperature that detects and first threshold temperature and Second Threshold temperature
Size；
Control heating module, for the control reacting by heating region when conversion zone temperature is less than first threshold temperature to the
One threshold temperature；
Test module, for when conversion zone temperature is not less than first threshold temperature, carrying out testing for preset content
Arrive test value；
Correction module, for when conversion zone temperature higher than first threshold temperature and less than Second Threshold temperature when, according to
Conversion zone temperature obtains corresponding correction function, test value is corrected using the correction function and obtains desired value.
Preferably, the correction module includes：
Correction function acquisition submodule, for obtaining correction function set, includes in the selection correction function set
With the immediate temperature value of current conversion zone temperature, corresponding for temperature value correction function is defined as current conversion zone temperature
Spend corresponding correction function.
Preferably, the correction function is the linear relationship function for including the first correction coefficient and the second correction coefficient.
Preferably, the correction function acquisition submodule includes：
Correction function set acquisition submodule, for determining each experimental concentration value of the first preset number；
Determine each experimental temperature value higher than first threshold temperature and the second preset number less than Second Threshold temperature；
Carry out the test of the preset content of each experimental concentration when conversion zone temperature is each experimental temperature value respectively, obtain
Each experiment test value corresponding with each experimental concentration under every kind of experimental temperature value；
Conversion zone temperature be first threshold at a temperature of carry out each experimental concentration preset content test, obtain with respectively
Experimental concentration is corresponding each with reference to test value；
Conversion zone concentration is worth to for every kind of experiment with reference to test value and experiment test according to each experimental concentration is corresponding
During temperature value, first correction of the corresponding experiment test value with conversion zone temperature for the reference test value of first threshold temperature is
Number and the second correction coefficient；
The first correction coefficient according to every kind of experimental temperature value obtains corresponding correction function with the second correction coefficient.
Preferably, the controller also includes memory module, for storing the corresponding correction of each conversion zone temperature
Function.
Present invention also offers a kind of test temperature corrects system, including described controller, also include：
Temperature sensor, is connected with the input of the controller, for detecting conversion zone temperature and by the temperature
Information is sent to the controller；
Heater, is connected with the outfan of the controller, for the control information sent according to the controller
To lift conversion zone temperature.
Test temperature bearing calibration, controller and test temperature correction system that the application present invention is provided, detection reaction
Regional temperature, is heated to first threshold when the temperature of detection is less than first threshold and is tested, obtain target detection result, when
The temperature of detection is directly carried out test and obtains desired value when being first threshold, when the temperature of detection is higher than first threshold and less than the
The value that test is obtained is carried out desired value being obtained corresponding to the correction of the temperature during two threshold values, can enter in the case of different temperatures
Row test, carries out temperature adjustment or test result correction to obtain accurately according to current conversion zone temperature and threshold temperature relation
Test result, test equipment is required without constant temperature substantially, relatively low cost can be passed through and obtained accurately test knot
Really, accuracy and the efficiency of test are improved.
Description of the drawings
In order to be illustrated more clearly that the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing
Accompanying drawing to be used needed for having technology description is briefly described, it should be apparent that, drawings in the following description are only this
Inventive embodiment, for those of ordinary skill in the art, on the premise of not paying creative work, can be with basis
The accompanying drawing of offer obtains other accompanying drawings.
Fig. 1 is the flow chart of test temperature bearing calibration of the present invention；
Fig. 2 is the detail flowchart of test temperature bearing calibration of the present invention；
Fig. 3 is the structural representation of controller of the present invention；
Fig. 4 is the another structural representation of controller of the present invention；
Fig. 5 is the structural representation that test temperature of the present invention corrects system.
Specific embodiment
Accompanying drawing in below in conjunction with the embodiment of the present invention, to the embodiment of the present invention in technical scheme carry out clear, complete
Site preparation is described, it is clear that described embodiment is only a part of embodiment of the invention, rather than whole embodiment.It is based on
Embodiment in the present invention, it is every other that those of ordinary skill in the art are obtained under the premise of creative work is not made
Embodiment, belongs to the scope of protection of the invention.
The invention provides a kind of test temperature bearing calibration, as described in Figure 1, is test temperature bearing calibration of the present invention
First specific embodiment, including：
Step S101：Detection conversion zone temperature；
Detection obtains the temperature value of current conversion zone.
Step S102：Whether the conversion zone temperature is judged less than first threshold temperature, if it is, entering step
S103, otherwise enters step S104；
It is 24 DEG C such as to carry out preset first threshold value temperature when urine micro protein is tested.
Step S103：Reacting by heating region starts the test of preset content to first threshold temperature, using test value as
Desired value；
When conversion zone temperature is less than 24 DEG C of first threshold temperature, directly enter after carrying out being heated to 24 DEG C to conversion zone
Row test, and using test value as final goal value.
Step S104：Judge whether the conversion zone temperature is first threshold temperature, if it is, entering step
S105, otherwise enters step S106；
Judge whether conversion zone temperature is 24 DEG C when conversion zone temperature is not less than 24 DEG C of first threshold temperature.
Step S105：Directly start the test of preset content, using test value as desired value；
Directly tested when conversion zone temperature is 24 DEG C, using test value as final goal value.
Step S106：Whether the conversion zone temperature is judged higher than first threshold temperature and less than Second Threshold temperature,
If it is, entering step S107；
Judge conversion zone temperature whether higher than the first threshold when conversion zone temperature is not below or equal to first threshold temperature
It is worth temperature and less than Second Threshold temperature, it is 37 DEG C to preset Second Threshold temperature.
Step S107：Directly start the test of preset content, after obtaining test value, obtained according to conversion zone temperature corresponding
Correction function, test value is corrected using the correction function and obtains desired value.
When conversion zone temperature higher than 24 DEG C and less than 37 DEG C when directly start to test, obtain after obtaining test value instantly temperature
Spend corresponding correction function test value is corrected and obtain desired value, specifically, obtained according to conversion zone temperature corresponding
Correction function includes：Correction function set is obtained, is chosen including with current conversion zone temperature in the correction function set
Corresponding for temperature value correction function is defined as the corresponding correction function of current conversion zone temperature by immediate temperature value.
The test temperature bearing calibration that application the present embodiment is provided, detects conversion zone temperature, when the temperature of detection is less than
It is heated to first threshold to be tested during first threshold, obtains target detection result, straight when the temperature of detection is first threshold
Tap into capable test and obtain desired value, when the temperature of detection is entered to the value that test is obtained higher than first threshold and during less than Second Threshold
Row obtains desired value corresponding to the correction of the temperature, can be tested, according to current conversion zone in the case of different temperatures
Temperature carries out temperature adjustment or test result correction with threshold temperature relation to obtain accurate test result, to test equipment base
Originally there is no constant temperature requirement, accurate test result can be obtained by relatively low cost, improve accuracy and the effect of test
Rate.
The another embodiment of temperature test bearing calibration of the present invention, it is to include the first correction coefficient to arrange the correction function
With the linear relationship function of the second correction coefficient,
As shown in Fig. 2 specific, obtaining correction function set includes：
Step S201：Determine each experimental concentration value of the first preset number；
Gradient close 5 different experiments concentration value C1, C2, C3, C4, C5 are such as set.
Step S202：Determine each experiment higher than first threshold temperature and the second preset number less than Second Threshold temperature
Temperature value；
26 DEG C, 28 DEG C, 30 DEG C, 32 DEG C, 34 DEG C, 36 DEG C close of 6 different experiments temperature values of gradient are such as set.
Step S203：The preset content of each experimental concentration is carried out when conversion zone temperature is each experimental temperature value respectively
Test, obtains each experiment test value corresponding with each experimental concentration under every kind of experimental temperature value；
The test for carrying out 5 different experiments concentration under the 6 different experiments temperature conditionss for arranging respectively obtains experiment survey
Examination value.
Step S204：The survey of the preset content of each experimental concentration is carried out at a temperature of conversion zone temperature is first threshold
Examination, obtains corresponding with each experimental concentration each with reference to test value；
The test of 5 variable concentrations of the setting is carried out in the case of 24 DEG C of first threshold temperature, and the result for obtaining is
The reference test value of each concentration, as shown in table 1 below, it is that each experimental temperature value and the lower 5 kinds of experiments of first threshold temperature conditionss are dense
The test result of angle value：
Table 1
Step S205：Conversion zone concentration is worth to reference to test value and experiment test it is according to each experimental concentration is corresponding
Corresponding experiment test value and conversion zone temperature for the reference test value of first threshold temperature the during every kind of experimental temperature value
One correction coefficient and the second correction coefficient；
As a example by 26 DEG C, can be with 24 DEG C test value C01, C02, C03, C04, C05 as vertical coordinate, with 26 DEG C of test value
C11, C21, C31, C41, C51 are abscissa, obtain five points in a coordinate system, carry out scatterplot line and set up linear equation C=
k26*C1+b26, obtain the first correction coefficient k26With the second correction coefficient b26, can also similarly obtain the first school of other temperature
Positive coefficient k and the second correction coefficient b.
Step S206：The first correction coefficient according to every kind of experimental temperature value obtains corresponding correction with the second correction coefficient
Function.
Such as table 2 below, it is the correction function obtained with the second correction coefficient according to the first correction coefficient.
Table 2
Correction function is determined according to the first correction coefficient k of upper table and the second correction coefficient b.
When the bearing calibration of this test temperature is carried out, correction function collection is combined into the linear relationship set for having obtained, can be with
Directly choose include in correction function set with the immediate temperature value of current conversion zone temperature, will be corresponding for the temperature value
Correction function is defined as the corresponding correction function of current conversion zone temperature.
The present embodiment instrument test obtains test value C0, conversion zone temperature T is detected, the school that mates with temperature T-phase is chosen
Positive function, temperature T can adopt the correction function of temperature t in the case of being located at 1 DEG C of temperature t that correction function is obtained or so.
Specifically such as following table：
Table 3
| T(℃) | Correction function |
| 24 T≤25 | C=C0 |
| 25 T≤27 | C=k26*C1+b26 |
| 27 T≤29 | C=k28*C2+b28 |
| 29 T≤31 | C=k30*C3+b30 |
| 31 T≤33 | C=k32*C4+b32 |
| 33 T≤35 | C=k34*C5+b34 |
| 35 T≤37 | C=k36*C6+b36 |
| T 37 | Do not correct |
For example when testing, in the case of T=26 DEG C ± 1 DEG C, the correction function for adopting is for t=26 DEG C of feelings for conversion zone temperature
Correction function under condition is calculated final goal value.
As shown in table 4 below～table 8, before and after the test temperature bearing calibration for being application the present embodiment, urine micro protein is carried out
Test comparison result：
Default 24 DEG C is first threshold temperature, and 37 DEG C is Second Threshold temperature.
Table 4
Table 5
Table 6
Table 7
Table 8
As shown by data this method of above-mentioned experimental result carries out test result when microdose urine protein is tested according to temperature
Correction, can be very good to solve interference of the temperature to test result, while the temperature control to instrument is required also than relatively low, test be set
Standby basic without constant temperature requirement, accurate test result can be obtained by relatively low cost, improve the accuracy of test
With efficiency.
Present invention also offers a kind of controller, is applied to test temperature correction, as shown in figure 3, it is controller of the present invention
Structural representation, the controller includes：
Judge module 101, for judging the conversion zone temperature for detecting with first threshold temperature and Second Threshold temperature
The size of degree；
Control heating module 102, for the control reacting by heating region when conversion zone temperature is less than first threshold temperature
To first threshold temperature；
Test module 103, for when conversion zone temperature is not less than first threshold temperature, carrying out the test of preset content
Obtain test value；
Correction module 104, for when conversion zone temperature higher than first threshold temperature and less than Second Threshold temperature when, root
Corresponding correction function is obtained according to conversion zone temperature, test value is corrected using the correction function and is obtained desired value.
The still another embodiment of controller of the present invention, specifically, the correction module includes：
Correction function acquisition submodule, for obtaining correction function set, includes in the selection correction function set
With the immediate temperature value of current conversion zone temperature, corresponding for temperature value correction function is defined as current conversion zone temperature
Spend corresponding correction function.
Correction function described in the present embodiment is the linear relationship function for including the first correction coefficient and the second correction coefficient.
The correction function acquisition submodule includes：
Correction function set acquisition submodule, for determining each experimental concentration value of the first preset number；
Determine each experimental temperature value higher than first threshold temperature and the second preset number less than Second Threshold temperature；
Carry out the test of the preset content of each experimental concentration when conversion zone temperature is each experimental temperature value respectively, obtain
Each experiment test value corresponding with each experimental concentration under every kind of experimental temperature value；
Conversion zone temperature be first threshold at a temperature of carry out each experimental concentration preset content test, obtain with respectively
Experimental concentration is corresponding each with reference to test value；
Conversion zone concentration is worth to for every kind of experiment with reference to test value and experiment test according to each experimental concentration is corresponding
During temperature value, first correction of the corresponding experiment test value with conversion zone temperature for the reference test value of first threshold temperature is
Number and the second correction coefficient；
The first correction coefficient according to every kind of experimental temperature value obtains corresponding correction function with the second correction coefficient.
As shown in figure 4, for the still another embodiment of controller of the present invention, corresponding to Fig. 3, also including：Memory module
105, for storing the corresponding correction function of each conversion zone temperature.
Present invention also offers a kind of test temperature corrects system, as shown in figure 5, the structural representation for a specific embodiment
Figure, including weighing above-mentioned controller 201, also includes：
Temperature sensor 202, is connected with the input of the controller, for detecting conversion zone temperature and by the temperature
Degree information is sent to the controller；
Heater 203, is connected with the outfan of the controller, for the control letter sent according to the controller
Cease to lift conversion zone temperature.
The test temperature correction system that application the present embodiment is provided, detects conversion zone temperature, when the temperature of detection is less than
It is heated to first threshold to be tested during first threshold, obtains target detection result, straight when the temperature of detection is first threshold
Tap into capable test and obtain desired value, when the temperature of detection is entered to the value that test is obtained higher than first threshold and during less than Second Threshold
Row obtains desired value corresponding to the correction of the temperature, can be tested, according to current conversion zone in the case of different temperatures
Temperature carries out temperature adjustment or test result correction with threshold temperature relation to obtain accurate test result, to test equipment base
Originally there is no constant temperature requirement, accurate test result can be obtained by relatively low cost, improve accuracy and the effect of test
Rate.
For apparatus system class embodiment, due to itself and embodiment of the method basic simlarity, so the comparison of description is simple
Single, related part is illustrated referring to the part of embodiment of the method.
It should be noted that each embodiment in this specification is described by the way of going forward one by one, each embodiment weight
Point explanation is all difference with other embodiment, between each embodiment identical similar part mutually referring to.
Finally, in addition it is also necessary to explanation, herein, such as first and second or the like relational terms be used merely to by
One entity or operation are made a distinction with another entity or operation, and are not necessarily required or implied these entities or operation
Between exist any this actual relation or order.And, term " including ", "comprising" or its any other variant meaning
Covering including for nonexcludability, so that a series of process, method, article or equipment including key elements not only includes that
A little key elements, but also other key elements including being not expressly set out, or also include for this process, method, article or
The intrinsic key element of equipment.In the absence of more restrictions, the key element for being limited by sentence "including a ...", does not arrange
Remove and also there is other identical element in process, method, article or the equipment for including the key element.
Above method provided herein, controller and system are described in detail, used herein specifically
Individual example is set forth to the principle of the application and embodiment, and the explanation of above example is only intended to help and understands the application
Method and its core concept；Simultaneously for one of ordinary skill in the art, according to the thought of the application, it is being embodied as
Will change in mode and range of application, in sum, this specification content should not be construed as the restriction to the application.
Claims (10)
1. a kind of test temperature bearing calibration, it is characterised in that include：
Detection conversion zone temperature；
When the conversion zone temperature is less than first threshold temperature, start to preset behind reacting by heating region to first threshold temperature
The test of content, using test value as desired value；
When the conversion zone temperature is first threshold temperature, directly start the test of preset content, using test value as mesh
Scale value；
When the conversion zone temperature higher than first threshold temperature and less than Second Threshold temperature when, directly start preset content
Test, after obtaining test value, obtains corresponding correction function according to conversion zone temperature, using the correction function to test value
It is corrected and obtains desired value.
2. test temperature bearing calibration according to claim 1, it is characterised in that obtained according to conversion zone temperature corresponding
Correction function include：
Obtain correction function set, choose include in the correction function set with the immediate temperature of current conversion zone temperature
Corresponding for temperature value correction function is defined as the corresponding correction function of current conversion zone temperature by angle value.
3. test temperature bearing calibration according to claim 2, it is characterised in that the correction function is to include the first school
The linear relationship function of positive coefficient and the second correction coefficient.
4. test temperature bearing calibration according to claim 3, it is characterised in that obtaining correction function set includes：
Determine each experimental concentration value of the first preset number；
Determine each experimental temperature value higher than first threshold temperature and the second preset number less than Second Threshold temperature；
Carry out the test of the preset content of each experimental concentration when conversion zone temperature is each experimental temperature value respectively, obtain every kind of
Each experiment test value corresponding with each experimental concentration under experimental temperature value；
The test of the preset content of each experimental concentration is carried out at a temperature of conversion zone temperature is first threshold, is obtained and each experiment
Concentration is corresponding each with reference to test value；
Conversion zone concentration is worth to for every kind of experimental temperature with reference to test value and experiment test according to each experimental concentration is corresponding
During value, corresponding experiment test value and conversion zone temperature for the reference test value of first threshold temperature the first correction coefficient and
Second correction coefficient；
The first correction coefficient according to every kind of experimental temperature value obtains corresponding correction function with the second correction coefficient.
5. a kind of controller, it is characterised in that be applied to test temperature correction, the controller includes：
Judge module, for judging the big of the conversion zone temperature that detects and first threshold temperature and Second Threshold temperature
Little；
Control heating module, for the control reacting by heating region when conversion zone temperature is less than first threshold temperature to the first threshold
Value temperature；
Test module, for when conversion zone temperature is not less than first threshold temperature, the test for carrying out preset content is surveyed
Examination value；
Correction module, for when conversion zone temperature higher than first threshold temperature and less than Second Threshold temperature when, according to reaction
Regional temperature obtains corresponding correction function, test value is corrected using the correction function and obtains desired value.
6. controller according to claim 5, it is characterised in that the correction module includes：
Correction function acquisition submodule, for obtaining correction function set, choose include in the correction function set with work as
Corresponding for temperature value correction function is defined as current conversion zone temperature pair by the immediate temperature value of front conversion zone temperature
The correction function that answers.
7. controller according to claim 6, it is characterised in that the correction function is to include the first correction coefficient and
The linear relationship function of two correction coefficients.
8. controller according to claim 6, it is characterised in that the correction function acquisition submodule includes：
Correction function set acquisition submodule, for determining each experimental concentration value of the first preset number；
Determine each experimental temperature value higher than first threshold temperature and the second preset number less than Second Threshold temperature；
Carry out the test of the preset content of each experimental concentration when conversion zone temperature is each experimental temperature value respectively, obtain every kind of
Each experiment test value corresponding with each experimental concentration under experimental temperature value；
The test of the preset content of each experimental concentration is carried out at a temperature of conversion zone temperature is first threshold, is obtained and each experiment
Concentration is corresponding each with reference to test value；
Conversion zone concentration is worth to for every kind of experimental temperature with reference to test value and experiment test according to each experimental concentration is corresponding
During value, corresponding experiment test value and conversion zone temperature for the reference test value of first threshold temperature the first correction coefficient and
Second correction coefficient；
The first correction coefficient according to every kind of experimental temperature value obtains corresponding correction function with the second correction coefficient.
9. the controller according to any one of claim 6～8, it is characterised in that also include memory module, for storing
State the corresponding correction function of each conversion zone temperature.
10. a kind of test temperature corrects system, it is characterised in that including the controller described in any one of claim 5～9, also
Including：
Temperature sensor, is connected with the input of the controller, for detecting conversion zone temperature and by the temperature information
It is sent to the controller；
Heater, is connected with the outfan of the controller, is carried for the control information that sent according to the controller
Rise conversion zone temperature.
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| CN110007087B (en) * | 2019-04-12 | 2022-07-12 | 三诺生物传感股份有限公司 | Blood glucose measuring method based on rechargeable glucometer |
| CN112432988B (en) * | 2020-11-25 | 2023-03-03 | 重庆迈联医疗科技有限公司 | Temperature correction method of electrochemical test system |
| CN112540079B (en) * | 2020-12-02 | 2022-11-22 | 江苏盖睿健康科技有限公司 | Urine analysis device and method |
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| JP5134065B2 (en) * | 2009-12-22 | 2013-01-30 | 日本特殊陶業株式会社 | Sensor control device |
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