CN104740314A - Pharmaceutical composition for caring chronic nephritis - Google Patents

Pharmaceutical composition for caring chronic nephritis Download PDF

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Publication number
CN104740314A
CN104740314A CN201510078220.0A CN201510078220A CN104740314A CN 104740314 A CN104740314 A CN 104740314A CN 201510078220 A CN201510078220 A CN 201510078220A CN 104740314 A CN104740314 A CN 104740314A
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parts
herba
pharmaceutical composition
fructus
chronic nephritis
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CN201510078220.0A
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Chinese (zh)
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周传巧
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Individual
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Individual
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Priority to CN201510078220.0A priority Critical patent/CN104740314A/en
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Abstract

The invention relates to a pharmaceutical composition for caring chronic nephritis. The pharmaceutical composition for caring chronic nephritis comprises the following raw materials in parts by weight: 10-20 parts of ford nervilia leaf, 10-30 parts of striate loosestrife herb, 1-20 parts of forest Horsetail, 20-30 parts of Iran speedwell herb, 20-30 parts of viburnum odoratissimum Ker, 10-20 parts of Lysimachia foenum-graecum Hance, 10-30 parts of kazinoki papermulberry branchlet and leaf, 10-30 parts of bigleaf goldsaxifrage herb, 10-20 parts of Pronephrium penangianum(Hook.) Holtt., 1-10 parts of ipomoea quamoclit, 1-10 parts of Chinese anise, 1-20 parts of gallnut, 10-30 parts of dateplum persimmon fruit, 1-20 parts of caudate lobe rare fern, 10-20 parts of loranthus kaempferi, 10-30 parts of homeysuckle stem, 1-10 parts of black locust flower, 5-15 parts of bower actinidia fruit and 1-10 parts of licorice. In the pharmaceutical composition for caring chronic nephritis, the components are combined and the prescription is resonable, so that the pharmaceutical composition for caring chronic nephritis has the characteristics of obvious curative effect, high safely and convenience, no toxic or side effect and low cost.

Description

A kind of pharmaceutical composition of nursing chronic nephritis
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of pharmaceutical composition of nursing chronic nephritis.
Background technology
Chronic nephritis is clinical common primary glomeruli disease, and clinical manifestation mostly is IgA nephropathy, gross hematuria or microscopic hematuria, and with edema, hypertension that degree is different, renal insufficiency appears in late period.And elimination or minimizing albuminuria are prevention glomerular sclerosiss and delay one of major measure entering renal insufficiency.Up to now, western medicine is owing to can cause burden to kidney, and thus effect is general.
Summary of the invention
The object of this invention is to provide a kind of pharmaceutical composition of nursing chronic nephritis.
In order to realize object of the present invention, the invention provides a kind of pharmaceutical composition of nursing chronic nephritis, it is made up of the crude drug of following weight portion: Folium Nerviliae fordii 10-20 part, Herba Lysimachiae Grammicae 10-30 part, Equisetum sylvaticum L. 1-20 part, Herba Veronicae Persicae 20-30 part, Lignum Acronychiae 20-30 part, Herba Lysimachiae foenum-graeci 10-20 part, Folium et Cacumen Broussonetiae Kazinoki 10-30 part, Herba Chrysosplenii Macrophylli 10-30 part, Sanguis Gallus domesticus lotus 10-20 part, cypress vine pine 1-10 part, Fructus Anisi Stellati 1-10 part, Galla Turcica (Galla Helepensis) 1-20 part, Fructus Dispyroris Loti 10-30 part, the rare sub-Herba pteridii latiusculi 1-20 part of caudal lobe, Taxillus caloreas (Diels) Danser 10-20 part, Caulis Lonicerae 10-30 part, Flos Robiniae Pseudoacaciae 1-10 part, Fructus Actinidiae Argutae 5-15 part and Radix Glycyrrhizae 1-10 part.
Preferably, the pharmaceutical composition of described nursing chronic nephritis is made up of the crude drug of following weight portion: Folium Nerviliae fordii 15 parts, Herba Lysimachiae Grammicae 20 parts, Equisetum sylvaticum L. 10 parts, Herba Veronicae Persicae 25 parts, Lignum Acronychiae 25 parts, Herba Lysimachiae foenum-graeci 12 parts, Folium et Cacumen Broussonetiae Kazinoki 20 parts, Herba Chrysosplenii Macrophylli 20 parts, 15 parts, Sanguis Gallus domesticus lotus, cypress vine pine 8 parts, Fructus Anisi Stellati 5 parts, Galla Turcica (Galla Helepensis) 10 parts, Fructus Dispyroris Loti 20 parts, the rare sub-Herba pteridii latiusculi 10 parts of caudal lobe, Taxillus caloreas (Diels) Danser 12 parts, Caulis Lonicerae 20 parts, Flos Robiniae Pseudoacaciae 8 parts, Fructus Actinidiae Argutae 10 parts and 9 parts, Radix Glycyrrhizae.
More preferably, described pharmaceutical composition can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, patch or decoction.
The present invention also provides the purposes of compositions in the medicine of preparation nursing chronic nephritis, described compositions is made up of the crude drug of following weight portion: Folium Nerviliae fordii 10-20 part, Herba Lysimachiae Grammicae 10-30 part, Equisetum sylvaticum L. 1-20 part, Herba Veronicae Persicae 20-30 part, Lignum Acronychiae 20-30 part, Herba Lysimachiae foenum-graeci 10-20 part, Folium et Cacumen Broussonetiae Kazinoki 10-30 part, Herba Chrysosplenii Macrophylli 10-30 part, Sanguis Gallus domesticus lotus 10-20 part, cypress vine pine 1-10 part, Fructus Anisi Stellati 1-10 part, Galla Turcica (Galla Helepensis) 1-20 part, Fructus Dispyroris Loti 10-30 part, the rare sub-Herba pteridii latiusculi 1-20 part of caudal lobe, Taxillus caloreas (Diels) Danser 10-20 part, Caulis Lonicerae 10-30 part, Flos Robiniae Pseudoacaciae 1-10 part, Fructus Actinidiae Argutae 5-15 part and Radix Glycyrrhizae 1-10 part.
Preferably, described compositions is made up of the crude drug of following weight portion: Folium Nerviliae fordii 15 parts, Herba Lysimachiae Grammicae 20 parts, Equisetum sylvaticum L. 10 parts, Herba Veronicae Persicae 25 parts, Lignum Acronychiae 25 parts, Herba Lysimachiae foenum-graeci 12 parts, Folium et Cacumen Broussonetiae Kazinoki 20 parts, Herba Chrysosplenii Macrophylli 20 parts, 15 parts, Sanguis Gallus domesticus lotus, cypress vine pine 8 parts, Fructus Anisi Stellati 5 parts, Galla Turcica (Galla Helepensis) 10 parts, Fructus Dispyroris Loti 20 parts, the rare sub-Herba pteridii latiusculi 10 parts of caudal lobe, Taxillus caloreas (Diels) Danser 12 parts, Caulis Lonicerae 20 parts, Flos Robiniae Pseudoacaciae 8 parts, Fructus Actinidiae Argutae 10 parts and 9 parts, Radix Glycyrrhizae.
More preferably, described medicine can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, patch or decoction.
In the present invention, Folium Nerviliae fordii, Herba Lysimachiae Grammicae are monarch drug; Equisetum sylvaticum L., Herba Veronicae Persicae, Lignum Acronychiae, Herba Lysimachiae foenum-graeci, Folium et Cacumen Broussonetiae Kazinoki are ministerial drug; Herba Chrysosplenii Macrophylli, Sanguis Gallus domesticus lotus, cypress vine pine, Fructus Anisi Stellati, Galla Turcica (Galla Helepensis), Fructus Dispyroris Loti, the rare sub-Herba pteridii latiusculi of caudal lobe, Taxillus caloreas (Diels) Danser, Caulis Lonicerae, Flos Robiniae Pseudoacaciae, Fructus Actinidiae Argutae are adjuvant drug; Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, plays the effect making medicine in the compositions of the present invention.
All medicines are harmonious in the present invention, reasonable recipe, have determined curative effect, safe ready, have no side effect, cheap feature.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment decoction of the present invention
Take Folium Nerviliae fordii 15 grams, Herba Lysimachiae Grammicae 20 grams, Equisetum sylvaticum L. 10 grams, Herba Veronicae Persicae 25 grams, Lignum Acronychiae 25 grams, Herba Lysimachiae foenum-graeci 12 grams, Folium et Cacumen Broussonetiae Kazinoki 20 grams, Herba Chrysosplenii Macrophylli 20 grams, 15 grams, Sanguis Gallus domesticus lotus, cypress vine pine 8 grams, Fructus Anisi Stellati 5 grams, Galla Turcica (Galla Helepensis) 10 grams, Fructus Dispyroris Loti 20 grams, the rare sub-Herba pteridii latiusculi 10 grams of caudal lobe, Taxillus caloreas (Diels) Danser 12 grams, Caulis Lonicerae 20 grams, Flos Robiniae Pseudoacaciae 8 grams, Fructus Actinidiae Argutae 10 grams and 9 grams, Radix Glycyrrhizae, add 3000 milliliters of ethanol, heating 1 hour under the condition of backflow, be cooled to room temperature, filter, 8000 ml waters are added in filtrate, place 24 hours under the condition that room temperature is closed, filter, decoction of the present invention is obtained after the ethanol reclaim under reduced pressure in filtrate is complete.
Experimental example
The diagnosis of all patients 50 example meet " nephrology " chronic glomerulonephritis of Wang Haiyan chief editor diagnostic criteria (Wang Haiyan, Liu Ping, Zhang Ming and, etc. nephrology [M]. Beijing: People's Health Publisher, 1996:697-699).Other secondary glomerulonephritises are all eliminated.Wherein man 24 example, female 26 example; Age 22-42 year, average 31 years old, course of disease 1-3, average 1.4 years.There is hematuria in 18 routine patients, slight azotemia appears in 21 routine patients, and hypertension appears in 11 routine patients.
Inclusive criteria
1. age >=22 years old; 2. serum creatinine (SCr)≤177 μm ol/L; 3. sign Informed Consent Form.
Exclusion standard
1. Secondary cases nephritis; 2. gestation, women breast-feeding their children; 3. severe psychiatric, dysnoesia or hepatic and renal function are entirely little; 4. allergic constitution.
Decoction prepared by oral embodiment is treated, every day 2 times, oral 100 milliliters at every turn, continuously treatment 20 days.
Efficacy determination
Alleviate: urine protein quantitation < 0.4g/24h, urine R-RBC < 2/HP, normal renal function, symptom, sign disappear; Effective: urine protein examination declines more than 50%, normal renal function or normal (differ with normal value and be no more than 15%) before continuing to reduce ratio treatment, and symptom, sign make moderate progress; Invalid: not reach effective standard.
Therapeutic outcome
Through treatment, find in 50 routine patients, alleviate 26 examples, effective 22 examples, invalid 2 examples, total effective rate is 96%.And do not find obvious untoward reaction over the course for the treatment of.

Claims (6)

1. nurse the pharmaceutical composition of chronic nephritis for one kind, it is characterized in that, it is made up of the crude drug of following weight portion: Folium Nerviliae fordii 10-20 part, Herba Lysimachiae Grammicae 10-30 part, Equisetum sylvaticum L. 1-20 part, Herba Veronicae Persicae 20-30 part, Lignum Acronychiae 20-30 part, Herba Lysimachiae foenum-graeci 10-20 part, Folium et Cacumen Broussonetiae Kazinoki 10-30 part, Herba Chrysosplenii Macrophylli 10-30 part, Sanguis Gallus domesticus lotus 10-20 part, cypress vine pine 1-10 part, Fructus Anisi Stellati 1-10 part, Galla Turcica (Galla Helepensis) 1-20 part, Fructus Dispyroris Loti 10-30 part, the rare sub-Herba pteridii latiusculi 1-20 part of caudal lobe, Taxillus caloreas (Diels) Danser 10-20 part, Caulis Lonicerae 10-30 part, Flos Robiniae Pseudoacaciae 1-10 part, Fructus Actinidiae Argutae 5-15 part and Radix Glycyrrhizae 1-10 part.
2. the pharmaceutical composition of nursing chronic nephritis according to claim 1, it is characterized in that, it is made up of the crude drug of following weight portion: Folium Nerviliae fordii 15 parts, Herba Lysimachiae Grammicae 20 parts, Equisetum sylvaticum L. 10 parts, Herba Veronicae Persicae 25 parts, Lignum Acronychiae 25 parts, Herba Lysimachiae foenum-graeci 12 parts, Folium et Cacumen Broussonetiae Kazinoki 20 parts, Herba Chrysosplenii Macrophylli 20 parts, 15 parts, Sanguis Gallus domesticus lotus, cypress vine pine 8 parts, Fructus Anisi Stellati 5 parts, Galla Turcica (Galla Helepensis) 10 parts, Fructus Dispyroris Loti 20 parts, the rare sub-Herba pteridii latiusculi 10 parts of caudal lobe, Taxillus caloreas (Diels) Danser 12 parts, Caulis Lonicerae 20 parts, Flos Robiniae Pseudoacaciae 8 parts, Fructus Actinidiae Argutae 10 parts and 9 parts, Radix Glycyrrhizae.
3. the pharmaceutical composition of nursing chronic nephritis according to claim 2, is characterized in that, described pharmaceutical composition can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, patch or decoction.
4. the purposes of compositions in the medicine of preparation nursing chronic nephritis, it is characterized in that, described compositions is made up of the crude drug of following weight portion: Folium Nerviliae fordii 10-20 part, Herba Lysimachiae Grammicae 10-30 part, Equisetum sylvaticum L. 1-20 part, Herba Veronicae Persicae 20-30 part, Lignum Acronychiae 20-30 part, Herba Lysimachiae foenum-graeci 10-20 part, Folium et Cacumen Broussonetiae Kazinoki 10-30 part, Herba Chrysosplenii Macrophylli 10-30 part, Sanguis Gallus domesticus lotus 10-20 part, cypress vine pine 1-10 part, Fructus Anisi Stellati 1-10 part, Galla Turcica (Galla Helepensis) 1-20 part, Fructus Dispyroris Loti 10-30 part, the rare sub-Herba pteridii latiusculi 1-20 part of caudal lobe, Taxillus caloreas (Diels) Danser 10-20 part, Caulis Lonicerae 10-30 part, Flos Robiniae Pseudoacaciae 1-10 part, Fructus Actinidiae Argutae 5-15 part and Radix Glycyrrhizae 1-10 part.
5. purposes according to claim 4, it is characterized in that, described compositions is made up of the crude drug of following weight portion: Folium Nerviliae fordii 15 parts, Herba Lysimachiae Grammicae 20 parts, Equisetum sylvaticum L. 10 parts, Herba Veronicae Persicae 25 parts, Lignum Acronychiae 25 parts, Herba Lysimachiae foenum-graeci 12 parts, Folium et Cacumen Broussonetiae Kazinoki 20 parts, Herba Chrysosplenii Macrophylli 20 parts, 15 parts, Sanguis Gallus domesticus lotus, cypress vine pine 8 parts, Fructus Anisi Stellati 5 parts, Galla Turcica (Galla Helepensis) 10 parts, Fructus Dispyroris Loti 20 parts, the rare sub-Herba pteridii latiusculi 10 parts of caudal lobe, Taxillus caloreas (Diels) Danser 12 parts, Caulis Lonicerae 20 parts, Flos Robiniae Pseudoacaciae 8 parts, Fructus Actinidiae Argutae 10 parts and 9 parts, Radix Glycyrrhizae.
6. purposes according to claim 5, is characterized in that, described medicine can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, patch or decoction.
CN201510078220.0A 2015-02-13 2015-02-13 Pharmaceutical composition for caring chronic nephritis Pending CN104740314A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20130060611A (en) * 2011-11-30 2013-06-10 (주)제주사랑농수산 Anti-inflammatory composition using a flower extract of citrus unshiu

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20130060611A (en) * 2011-11-30 2013-06-10 (주)제주사랑농수산 Anti-inflammatory composition using a flower extract of citrus unshiu

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
钟坚: "《钟坚医论医案选》", 31 December 2014, 浙江大学出版社 *

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