CN104614371A - Method for detecting biochemical indexes of excrement in toilet and detection equipment using same - Google Patents
Method for detecting biochemical indexes of excrement in toilet and detection equipment using same Download PDFInfo
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- CN104614371A CN104614371A CN201510081339.3A CN201510081339A CN104614371A CN 104614371 A CN104614371 A CN 104614371A CN 201510081339 A CN201510081339 A CN 201510081339A CN 104614371 A CN104614371 A CN 104614371A
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Abstract
The invention discloses a method for detecting biochemical indexes of excrement in a toilet and detection equipment using the method. The biochemical indexes of the excrement can be directly detected in a closestool, the detection result can be directly seen after defecating or flushing, and the use is convenient. The equipment is high in degree of automation, and continuous conventional detection is conveniently performed; foam serves as a color developing agent carrier, the observation is easy, and the interference of turbid sewage on the observation result is eliminated. The foam dispersion effect is good, the color developing agent and the substrate can be uniformly dispersed in a water seal, the dosage is saved, and convenient observation is realized; and moreover, according to a surfactant in the foam, the detection sensitivity is improved.
Description
Technical field
The present invention relates to the technical field of closet, particularly relate to a kind of method detecting excreta biochemical indicator in closet and the checkout equipment using the method.
Background technology
Be implied with multiple naked eyes biochemical indicator inconspicuous in excreta, comprise occult blood, glucose in urine, nitrite, pH value etc., these information are to finding that disease has important value in advance.For occult blood, occult blood refers to that hemorrhage of digestive tract amount is little, and naked eyes lose color, and a small amount of red blood cell is also had no way of under digested decomposition so that microscope again the hemorrhage situation that finds.Occult blood examination has important value to the multiple hemorrhage of digestive tract disease of diagnosis, is also the effective means of generaI investigation screening tumor in digestive tract.Clinical research confirmation, with the hemorrhage abnormal occurrence being early stage intestinal cancer and uniquely can finding of the trace of cancerous swelling in ight soil.
Clinical conventional occult blood test, mainly contains chemical method and immunological method.Chemical method has Ortho-tolidine method, phenolphthalin method, benzidine method, aminopyrine method, Guaiacolate method etc.Its principle, based on the hydrogen peroxide in the iron content protoheme energy catalytic reagent in haemoglobin, makes its release new ecological oxygen, is oxidized above-mentioned chromogen substance and develops the color.The depth of colour developing reflect haemoglobin number, that is the size of amount of bleeding.Although chemical method is not as immunological method high specificity, simple, be applicable to family's general election.
At present superoxide and colour developing group are combined as tetramethyl benzidine and are made test strips by existing market product, sticked in urine or ight soil aqueous solution, when there is occult blood, heme in haemoglobin can oxygen evolution in superoxide out, and tetramethyl benzidine oxidation is demonstrated special blueness.
This kind of method is comparatively easy, but needs 4 different test paper to determine blank, and needs positive control to check whether superoxide is expired.And more crucially, its operation steps is many, bothers and be not suitable for long-term continuous detecting.
Other excreta biochemical indicators also have and technical matters like occult blood detection type.
Summary of the invention
Technical matters to be solved by this invention is for the above-mentioned state of the art, and can when people goes to toilet for one, the method and structure of the state of a certain biochemical indicator in excreta just can be determined by the color change of foam on water in closet or the water surface, the reagent automatic powder adding realizing color reaction is added to toilet water sealing, without the need to people manual add test-paper.
The present invention solves the problems of the technologies described above adopted technical scheme:
In closet, detect a method for excreta biochemical indicator, it is characterized in that: comprise the following steps:
Step one, the developer of meeting the colour developing of excreta biochemical component containing at least one is stored in the medicament storage part of closet;
Step 2, when people goes to toilet, the component quantifying containing developer is transported to closet water-sealing part, water seal color is now blank,
Step 3, when in ight soil or urine containing corresponding with developer biochemical component time, developer and its reaction generate macroscopic particular color, and namely this color change can be used as the instruction containing the biochemical component corresponding with developer in excreta.
For optimizing technique scheme, the concrete measure taked also comprises:
It can be the substrate part of nascent oxygen and the coloured moiety with colour developing group that can be oxidized by nascent oxygen by blood constituent catalysis that developer at least comprises a kind of.
Excreta biochemical indicator comprises one or more in occult blood, glucose in urine, nitrite, pH value; Correspondingly, the developer substrate corresponding with occult blood is hydrogen peroxide, and colour developing group is tetramethyl benzidine; The developer substrate corresponding with glucose in urine is the composition of glucose oxidase and peroxidase, and colour developing group is potassium iodide; The developer substrate corresponding with nitrite is the 0.5g sulfanilic acid in Griess reagent, and colour developing group is αnaphthylamine; The developer corresponding with pH value is pH indicator.
Color composition also comprises at least one surfactant.
Surfactant is anionic surfactant, and the effective concentration of anionic surfactant in closet water seal is 0.1 ~ 4mmol/L.
Anionic surfactant is lauryl sodium sulfate, and the effective concentration of lauryl sodium sulfate in closet water seal is 1 ~ 3mmol/L.
Comprise foam generating system, first a part for developer enters the front end of foam generating system, and is dispersed to together with surfactant and is transported to closet water seal surface in foam and with the form of foam.
First substrate part is exhausted into toilet water sealing with foam, and after reaching finite concentration, coloured moiety enters with foam again, finally form the substrate part of higher concentration in water, and the coloured moiety of higher concentration is at froth bed.
The ingredient of foam also comprise can chelated iron ion, calcium ion, magnesium ion and other can contribute to the complexing agent of the metal cation component that ceramic incrustation scale produces, complexing agent can the time joins in water seal at certain intervals, in order to as negative control and reduce water quality on detect impact.
In closet, detect an equipment for excreta biochemical indicator, comprise the developer storage part and developer delivery section and conveying switch that store developer, described developer delivery section is provided with pumping installations and is connected to the delivery pipe outlet of toilet water sealing.
Developer storage part includes substrate storage part, colour developing thing storage part, and substrate storage part, colour developing thing storage part are connected on each self-corresponding pumping installations respectively by respective pipeline, thus realize point other pumping control.
Developer storage part also comprises surfactant storage part, and surfactant storage part is connected on corresponding pumping installations by pipeline.
Also comprise the frother that air, water and surfactant can be utilized to produce foam, developer delivery section is connected with frother front end, makes frother when manufacturing foam, developer is in the foam dispersed.
Delivery pipe outlet, in the bottom of closet pelvic cavity, makes foam enter closet from the below of closet pelvic cavity.
Compared with prior art, the present invention directly can carry out the detection of excreta biochemical indicator in toilet, and directly can see testing result when washing by water, easy to use, structure automation degree of the present invention is high, is convenient to continuous conventional sense; Adopt foam as developer carrier, be easy to observe, eliminate the muddy interference to observations of sewage.Foam dispersion is effective, can evenly spread in water seal by developer and substrate, saves dosing, is convenient to observe; The surfactant contained in foam, especially anionic surfactant can improve the catalytic efficiency of protoheme to peroxide substrate, improve detection sensitivity.
The present invention can detect multiple excreta biochemical indicator, such as by developer substrate hydrogen peroxide, colour developing group is that tetramethyl benzidine detects occult blood, when there is occult blood, heme in haemoglobin can oxygen evolution in superoxide out, and tetramethyl benzidine oxidation is demonstrated special blueness.Same step and method can also detect the content of glucose in urine, only need composition substrate part being changed into glucose oxidase and peroxidase, glucose Hydrogen Peroxide in glucose oxidase enzymatic urine, hydrogen peroxide is generated oxygen by Catalyzed Synthesis By Peroxidase again, oxygen again developer portion as potassium iodide is oxidized to coloured brown color.
Same method can also detect the existence of urine nitrite, and only substrate part need be changed into the 0.5g sulfanilic acid in Griess reagent, coloured moiety is replaced by αnaphthylamine.The nitrous acid run in urine when these two kinds of materials will present aubergine.
Can also detect pH change in ight soil, urine equally, only need replace coloured moiety pH indicator, and as bromthymol blue, micro-yellow in acid situation is blue under alkali condition.Ight soil and urine can be indicated whether to be in normal value.Without the need to adding substrate component.
The effect that foam of the present invention plays in the art:
1, be the spreading agent of medicament, effect medicament being dispersed in water seal can be played;
2, prevent the medicament of some toxicity to dabble application on human skin;
3, the anionic surfactant in foam improves the sensitivity detected of occulting blood;
4, the decontamination composition that foam contains contributes to reducing last time between each detection when using interfering material residual.
Accompanying drawing explanation
Fig. 1 is the structural representation of first embodiment of the invention;
Fig. 2 is the structural representation of second embodiment of the invention;
Fig. 3 is the structural representation of third embodiment of the invention;
Fig. 4 is the structural representation of developer storage part and foam generating system in Fig. 3
Fig. 5 is two kinds of structural representations one of fourth embodiment of the invention;
Fig. 6 is two kinds of structural representations two of fourth embodiment of the invention;
Fig. 7 is that surfactant concentration affects the table of comparisons to haemoglobin catalytic activity.
Embodiment
Below in conjunction with accompanying drawing, embodiments of the invention are described in further detail.
First embodiment: as shown in Figure 1,
Developer storage part comprises two separate space, substrate storage part 11, colour developing thing storage part 12, substrate storage part 11 stores substrate part, as hydrogen peroxide, colour developing thing storage part 12 stores coloured moiety, as tetramethyl benzidine, when opening conveying switch 6, the pump of pumping installations 4 is started working, and substrate part is injected into closet water seal, when reach a certain amount of after stopping.Pump is started working, when reach a certain amount of after stopping.After excreta falls into the water, if can discharge haemoglobin containing blood constituent, it is understood substrate oxidation and discharges nascent oxygen, is then oxidized by coloured moiety again thus produces distinctive blueness.
Second embodiment: as shown in Figure 2,
On the basis of the first embodiment, developer storage part increases the 3rd separate space, surfactant storage part 13, for storage surface activating agent, when after unlatching conveying switch 6, first the corresponding pump of surfactant storage part 13 starts, after pumping is a certain amount of, the corresponding pump of the corresponding pump of substrate storage part 11, colour developing thing storage part 12 again order is started working, until reach the concentration detecting and can use.
3rd embodiment: as shown in Figure 3 and Figure 4,
When ight soil causes water seal muddy, will impurity unnecessary in developer and ight soil be caused to react, as first, second embodiment uses merely chromogenic reagent will become not obvious.The present embodiment increases frother 5, and first a part for developer enters the front end of foam generating system, and is dispersed to together with surfactant and is transported to closet water seal surface in foam and with the form of foam.
Because foam is by air, the aggregation of a large amount of micro air bubbles that surfactant and water are formed, makes closet have splash-proof in use, intercepts the effect of bacterium diffusion.Foam also has other some characteristics that developer can be made more fully effectively to play a role:
Haemproteins residue problem possible when the preventing splash that foam has decreases many person-times of use toilets;
The generation of foam is all by surfactant-dispersed in water, after developer joins foam, can be dispersed in toilet water sealing surface sufficiently uniformly, be easy to realize observing effect.
Foam decreases people and visually sees feeling sick of ight soil, adds the aesthetics of product.
Fig. 4 is foam-making apparatus 5, comprises air pump 51, porous aerator 52, foaming box 53, water intaking valve 54, foam efferent duct 55, when startup conveying switch 6, the pump that surfactant storage part 13 is corresponding and the corresponding pump of substrate storage part 11 start, by substrate part simultaneously, surfactant is filled into foaming box 53, water intaking valve 54 is opened, and water can be allowed to enter, and air pump 51 is opened, pass into air to 52, substrate is attached to foam surface and enters into closet water seal by foam pipeline 55.After substrate reaches finite concentration in water seal, the pump stopping that substrate storage part 11 is corresponding, the pump of colour developing thing storage part 12 correspondence is opened, and colour developing group enters foam and enters into closet water seal by foam pipeline 55.
Send out form of foam as another kind: the highly pressurised liquid that foam-making apparatus can be through gas molten is discharged by Venturi tube and formed, also can directly use Venturi tube the aqueous solution air-breathing containing compositions such as surfactants discharged again and form foam.
4th embodiment: as shown in Figure 5 and Figure 6;
When faecal density sinks to greatly below water seal or when measuring few, do not have enough haemoglobins in water seal, in order to increase detection sensitivity, embodiment four is realized by injection orifice developer inlet port being arranged on siphonage-toilet.Other parts are with the 3rd embodiment, and the outlet of foam pipeline 55 not above closet pelvic cavity, but is arranged on the position of spray-hole.When foam enters from below, trickle foam fully mixes with the haemoglobin that contains in ight soil, and its nascent oxygen obtained by far away more than the situation injecting developer from top, thus obtains more accurate testing result.
5th embodiment:
On the basis of the 4th embodiment, newly increase separate space, metal chelating agent storage part, metal chelating agent is added in metal chelating agent storage part, as EDTA, under the state of not carrying out detecting, the pump corresponding by switch control rule metal chelating agent storage part adds certain density metal chelating agent in water seal, reduces the impact of fouling and metal pair detection.
The ultimate density of surfactant of the present invention has certain influence to the sensitivity measured, surfactant concentration is on the impact of haemoglobin catalytic activity as can be seen from Figure 7, in the present invention, the ultimate density of surfactant controls between 1 ~ 4mmol/L, and preferred concentration is 1 ~ 3mmol/L.
Below be only the preferred embodiment of the present invention, protection scope of the present invention be not only confined to above-described embodiment, all technical schemes belonged under thinking of the present invention all belong to protection scope of the present invention.It should be pointed out that for those skilled in the art, some improvements and modifications without departing from the principles of the present invention, should be considered as protection scope of the present invention.
Claims (14)
1. in closet, detect a method for excreta biochemical indicator, it is characterized in that: comprise the following steps:
Step one, the developer of meeting the colour developing of excreta biochemical component containing at least one is stored in the medicament storage part of closet;
Step 2, when people goes to toilet, the component quantifying containing developer is transported to closet water-sealing part, water seal color is now blank,
Step 3, when in ight soil or urine containing corresponding with developer biochemical component time, developer and its reaction generate macroscopic particular color, and namely this color change can be used as the instruction containing the biochemical component corresponding with developer in excreta.
2. a kind of method detecting excreta biochemical indicator in closet according to claim 1, is characterized in that: it can be the substrate part of nascent oxygen and the coloured moiety with colour developing group that can be oxidized by described nascent oxygen by blood constituent catalysis that described developer at least comprises a kind of.
3. a kind of method detecting excreta biochemical indicator in closet according to claim 2, is characterized in that: described excreta biochemical indicator comprises one or more in occult blood, glucose in urine, nitrite, pH value; Correspondingly, the developer substrate corresponding with occult blood is hydrogen peroxide, and colour developing group is tetramethyl benzidine; The developer substrate corresponding with glucose in urine is the composition of glucose oxidase and peroxidase, and colour developing group is potassium iodide; The developer substrate corresponding with nitrite is the 0.5g sulfanilic acid in Griess reagent, and colour developing group is αnaphthylamine; The developer corresponding with pH value is pH indicator.
4. a kind of method detecting excreta biochemical indicator in closet according to claim 2, is characterized in that: described color composition also comprises at least one surfactant.
5. a kind of method detecting excreta biochemical indicator in closet according to claim 4, it is characterized in that: described surfactant is anionic surfactant, the effective concentration of described anionic surfactant in closet water seal is 0.1 ~ 4mmol/L.
6. a kind of method detecting excreta biochemical indicator in closet according to claim 5, it is characterized in that: described anionic surfactant is lauryl sodium sulfate, the effective concentration of described lauryl sodium sulfate in closet water seal is 1 ~ 3mmol/L.
7. a kind of method detecting excreta biochemical indicator in closet according to claim 2, it is characterized in that: comprise foam generating system, first a part for described developer enters the front end of foam generating system, and is dispersed to together with described surfactant and is transported to closet water seal surface in foam and with the form of foam.
8. a kind of method detecting excreta biochemical indicator in closet according to claim 7, it is characterized in that: first described substrate part is exhausted into toilet water sealing with foam, after reaching finite concentration, coloured moiety enters with foam again, finally form the substrate part of higher concentration in water, and the coloured moiety of higher concentration is at froth bed.
9. a kind of method detecting excreta biochemical indicator in closet according to claim 8, it is characterized in that: the ingredient of described foam also comprise can chelated iron ion, calcium ion, magnesium ion and other can contribute to the complexing agent of the metal cation component that ceramic incrustation scale produces, described complexing agent can the time joins in water seal at certain intervals, in order to as negative control and reduce water quality on detect impact.
10. one kind is detected the equipment of excreta biochemical indicator in closet, it is characterized in that: comprise the developer storage part (1) and developer delivery section (2) and conveying switch (6) that store developer, described developer delivery section (2) is provided with pumping installations (4) and is connected to delivery pipe outlet (3) of toilet water sealing.
11. a kind of equipment detecting excreta biochemical indicator in closet according to claim 10, it is characterized in that: described developer storage part (1) includes substrate storage part (11), colour developing thing storage part (12), described substrate storage part (11), colour developing thing storage part (12) are connected on each self-corresponding pumping installations (4) respectively by respective pipeline, thus realize point other pumping control.
12. a kind of equipment detecting excreta biochemical indicator in closet according to claim 11, it is characterized in that: described developer storage part (1) also comprises surfactant storage part (13), described surfactant storage part (13) is connected on corresponding pumping installations (4) by pipeline.
13. a kind of equipment detecting excreta biochemical indicator in closet according to claim 10, it is characterized in that: also comprise the frother (5) that air, water and surfactant can be utilized to produce foam, developer delivery section (2) is connected with described frother (5) front end, makes frother (5) when manufacturing foam, developer is in the foam dispersed.
14. a kind of equipment detecting excreta biochemical indicator in closet according to claim 10, is characterized in that: described delivery pipe outlet (3), in the bottom of closet pelvic cavity, makes foam enter closet from the below of closet pelvic cavity.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201510081339.3A CN104614371A (en) | 2015-02-15 | 2015-02-15 | Method for detecting biochemical indexes of excrement in toilet and detection equipment using same |
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| CN201510081339.3A CN104614371A (en) | 2015-02-15 | 2015-02-15 | Method for detecting biochemical indexes of excrement in toilet and detection equipment using same |
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Cited By (7)
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| CN105136787A (en) * | 2015-08-28 | 2015-12-09 | 上海菲济生物科技有限公司 | Detection reagent for mono-hydroxyphenyl metabolin urine |
| CN106546755A (en) * | 2016-11-18 | 2017-03-29 | 曲阜师范大学 | A kind of occult blood speed is surveyed and uses capillary array preparation method and application |
| CN108999256A (en) * | 2018-07-12 | 2018-12-14 | 刘倩 | Based on big data can automatic push-pull partially embedded toilet |
| CN109632728A (en) * | 2018-12-26 | 2019-04-16 | 浙江瑞宝生物科技有限公司 | A kind of health monitoring intelligent closestool device and its occult blood detection method |
| CN110274902A (en) * | 2019-07-23 | 2019-09-24 | 珠海科域生物工程股份有限公司 | A kind of chemical method Test paper of fecal occult blood and preparation method thereof |
| CN112903668A (en) * | 2021-01-06 | 2021-06-04 | 勃森生命科技(上海)有限公司 | System and method capable of automatically and dynamically detecting excrement and closestool |
| CN114450454A (en) * | 2019-09-30 | 2022-05-06 | 骊住株式会社 | Functional unit for toilet system, and toilet system |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108999256A (en) * | 2018-07-12 | 2018-12-14 | 刘倩 | Based on big data can automatic push-pull partially embedded toilet |
| CN109632728A (en) * | 2018-12-26 | 2019-04-16 | 浙江瑞宝生物科技有限公司 | A kind of health monitoring intelligent closestool device and its occult blood detection method |
| CN110274902A (en) * | 2019-07-23 | 2019-09-24 | 珠海科域生物工程股份有限公司 | A kind of chemical method Test paper of fecal occult blood and preparation method thereof |
| CN114450454A (en) * | 2019-09-30 | 2022-05-06 | 骊住株式会社 | Functional unit for toilet system, and toilet system |
| CN112903668A (en) * | 2021-01-06 | 2021-06-04 | 勃森生命科技(上海)有限公司 | System and method capable of automatically and dynamically detecting excrement and closestool |
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