CN104606796A - Dose calculation error testing method of radiotherapy system and phantom - Google Patents

Dose calculation error testing method of radiotherapy system and phantom Download PDF

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Publication number
CN104606796A
CN104606796A CN201410055823.4A CN201410055823A CN104606796A CN 104606796 A CN104606796 A CN 104606796A CN 201410055823 A CN201410055823 A CN 201410055823A CN 104606796 A CN104606796 A CN 104606796A
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China
Prior art keywords
dose
body mould
radiotherapy system
detector
measurement
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Pending
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CN201410055823.4A
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Chinese (zh)
Inventor
张新
宋连有
刘毅
孙京昇
焦春营
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BEIJING INSTITUTE OF MEDICAL DEVICE TESTING
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BEIJING INSTITUTE OF MEDICAL DEVICE TESTING
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Priority to CN201410055823.4A priority Critical patent/CN104606796A/en
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Abstract

The invention relates to a dose calculation error testing method of a radiotherapy system and a phantom. The method includes test method for the dose calculation comprehensive error and the dose distribution calculation error, and the testing phantom corresponding to the test method. The method comprises the steps of processing a test phantom of a body multi-source gamma beam three-dimensional positioning radiotherapy system; positioning the test phantom on a therapy bed of the body multi-source gamma beam three-dimensional positioning radiotherapy system; radiating a radiation detector in the phantom; analyzing the measurement result obtained by the detector; calculating to obtain the therapy planning dose calculation comprehensive error and therapy planning dose distribution calculation error. The method is applied to standard and quantitative measurement of the body multi-source gamma beam three-dimensional positioning radiotherapy system.

Description

Radiotherapy system dosimetric error method of testing and body mould
Technical field
The present invention relates to a kind of for the method for testing of body multi-source gamma beam three-dimensional directional radiotherapy eutical system dosimetric error and the body mould of correspondence, belong to assessment measuring method and the equipment of radiotherapy system.
Background technology
Radiotherapy as one of the three large means for the treatment of malignant tumor, extensive use in medical institutions at home and abroad.Stereotactic radiotherapy is radiocurable one, uses the radionuclide with certain activity to use the collimator of a series of different size as radiation source, carries out irradiation by accurate localization method and radiacmeter pinpoint tumor of getting it right.Meanwhile, we notice radiotherapy while killing tumor cell also normal tissue organ irradiate, if improper use can damage patient and medical personnel.
Body Multi-source gamma beam three-dimensional directional radiotherapy eutical system uses multiple simultaneously 60co sealed radioactive source (radioactive source can be motion, also can be static) carries out spotlight to body lesion region.While killing tumor cell, the irradiation to tumor normal surrounding tissue organ can be reduced as far as possible.
Shown in Fig. 1 is a kind of body Multi-source gamma beam three-dimensional directional radiotherapy eutical system, comprise frame (1), radioactive source and collimator assembly (2), patient location or fixture (3), therapeutic bed (4), comprising can the therapeutic bed bed board (5) of horizontal movement.By the horizontal movement of bed board, the patient body position of needs treatment can be transported to the focal position (6) under radioactive source and collimator assembly (2), stereotactic radiotherapy is carried out to diseased region.
Body Multi-source gamma beam three-dimensional directional radiotherapy eutical system structure and principle comparatively complicated, not having like product abroad at present, is the large medical equipment that Hazard ratio is higher.The body Multi-source gamma beam three-dimensional directional radiotherapy eutical system of different manufacturers produce has different design philosophys and implementation method, up to the present, and the international and domestic test body mould still not having to make different systems compare on identical platform.
Summary of the invention
For above-mentioned technical problem of the prior art, the object of the present invention is to provide a kind of method and apparatus that can carry out standardization and quantitative evaluation measurement to body Multi-source gamma beam three-dimensional directional radiotherapy eutical system.
The present invention realizes by the following technical solutions.
For a body mould for radiotherapy system test, comprising:
Elliptic Cylinder framework, it has inner rectangular parallelepiped space;
At least one detector plate, can just be placed in the above-mentioned rectangular parallelepiped space of Elliptic Cylinder framework.
Preferably, described Elliptic Cylinder framework and detector plate with the use of time, can be judged by suitable labelling, the position of detector plate in Elliptic Cylinder framework.
Preferably, described Elliptic Cylinder framework and detector plate are made up of pmma material;
Preferably, described detector plate comprises multiple plate that ionization chamber detector can be coordinated to use, and these plates has the perforate of different size, for coordinating different ionization chamber detectors or semiconductor detector.
Preferably, described detector plate comprises multiple plate type that radiation developed film can be coordinated to use, and these plates has and prevents radiation developed film by the cassette of visible light exposure.
Preferably, described film cassette uses the density of impermeable visible ray to be 1g/cm substantially 3plastic material make.
Preferably, the rectangular parallelepiped space in described Elliptic Cylinder framework can allow to insert at least three plates simultaneously.
Preferably, described radiotherapy system is body multi-source gamma beam three-dimensional directional radiotherapy eutical system.
Present invention also offers the method using the body mould according to any one of above technical scheme to carry out radiotherapy system test, comprise the steps:
By the radiation detectors such as ionization chamber, quasiconductor, radiation developed film can detachably and adjustable ground be positioned in body multi-source gamma beam three-dimensional directional radiotherapy eutical system test body mould;
Body multi-source gamma beam three-dimensional directional radiotherapy eutical system test body mould is positioned on described body Multi-source gamma beam stereotactic radiotherapy therapeutic bed near system focus position, frame side;
Use described body Multi-source gamma beam three-dimensional directional radiotherapy eutical system, described ionization chamber, semiconductor radiation detector can obtain corresponding radiation dose measurement value in each measuring position, radiation developed film can obtain corresponding Radiation dose distribution data at each measurement plane;
Absorbed dose on the correspondence position calculate measurement result and body Multi-source gamma beam three-dimensional directional radiotherapy eutical system and dose distribution carry out data comparative analysis, obtain medical treatment planning software Rapid Dose Calculation synthetic error and therapy plot software dose distributions computation error, as the quantitative test index of body Multi-source gamma beam three-dimensional directional radiotherapy eutical system Rapid Dose Calculation.
Preferably, described step of measurement result being carried out data analysis comprises:
Read body Multi-source gamma beam three-dimensional directional radiotherapy eutical system Rapid Dose Calculation data;
Obtain the absorbed dose numerical value of the detector measurement point position such as ionization chamber, quasiconductor that body Multi-source gamma beam three-dimensional directional radiotherapy eutical system calculates;
Analysis, to the deviation between the value of calculation of the absorbed dose of each position and measured value, obtains the therapy plot software Rapid Dose Calculation synthetic error of each measuring position;
Obtain the absorbed-dose distribution data of the radiation developed film place plane that body Multi-source gamma beam three-dimensional directional radiotherapy eutical system calculates;
To each measurement plane, the area that the isodose analyzing in absorbed-dose distribution data 50% surrounds and film measurement obtains 50% the area that surrounds of isodose, analyze the area of above-mentioned two areas by overlapping after registration, the coincidence factor of the area that the isodose obtaining 50% of each measurement plane surrounds.
By above technical scheme, the present invention can carry out standardization to the therapy plot software Rapid Dose Calculation synthetic error of the body Multi-source gamma beam three-dimensional directional radiotherapy eutical system of various different vendor and therapy plot software dose distributions computation error and quantitative evaluation is measured.
Accompanying drawing explanation
Fig. 1 is body Multi-source gamma beam three-dimensional directional radiotherapy eutical system structural representation;
Fig. 2 is Elliptic Cylinder part-structure schematic diagram in test body mould of the present invention;
Fig. 3 is the structural representation of test body mould centerboard of the present invention.
Wherein each Reference numeral implication is as follows:
1, body Multi-source gamma beam three-dimensional directional radiotherapy eutical system frame; 2, radioactive source and collimator assembly; 33 D positioning equipments; 4, therapeutic bed; 5, therapeutic bed bed board; 6, focal position; 7, test body mould Elliptic Cylinder framework; 8, wedge shape fixing insertion; 9, semiconductor detector plate; 10, film cassette; 11, film cassette plate; 12, ionization chamber plate; 13, position adjustments plate.
Detailed description of the invention
A body Multi-source gamma beam three-dimensional directional radiotherapy eutical system method of testing for Standardized quantitative, and the measurement device of necessity.The body Multi-source gamma beam three-dimensional directional radiotherapy eutical system method of testing of the present invention's design, for body multi-source gamma beam three-dimensional directional radiotherapy eutical system therapy plot software dosimetric error method of testing, comprise the method for testing of Rapid Dose Calculation synthetic error and the dose distribution error of calculation; The measurement device of the present invention's design is the body mould for the test of body multi-source gamma beam three-dimensional directional radiotherapy eutical system.
The body multi-source gamma beam three-dimensional directional radiotherapy eutical system test body mould of the present invention's design is made up of pmma material, shape is Elliptic Cylinder feature, can the absorbed-dose distribution of simulated patient when carrying out body stereotactic radiotherapy in patient body.Body mould is made up of the framework of elliptic cylindrical shape and inner plate.The perforate of cuboid is had, the plate of placement difference in functionality that can be firm in perforate in Elliptic Cylinder.In the embodiment of recommending, plate can coordinate use and the dosage measurement of the radiation detectors such as ionization chamber, quasiconductor and radiation developed film; At least can place three plates in elliptical cylinder-shape framework, the plate measured for radiation developed film uses the density of impermeable visible ray as far as possible close to 1g/cm 3plastic material make.
The body multi-source gamma beam three-dimensional directional radiotherapy eutical system therapy plot software dosimetric error method of testing of the present invention's design comprises:
Image scanner is used to import in treatment planning systems to its scanning by the data of scanogram, formulate completed treatment plan, and record the Rapid Dose Calculation value of reference point locations, the dose distribution of output radiation developed film place measurement plane, and the area S that in calculated dose distribution, the isodose of 50% surrounds p
The body mould being used for the test of body multi-source gamma beam three-dimensional directional radiotherapy eutical system is fixed to the stereotactic frame (or therapeutic bed) of body Multi-source gamma beam three-dimensional directional radiotherapy eutical system
By the radiation detector such as ionization chamber, quasiconductor insertosome mould, its effective measurement point is overlapped with reference point; Special body mould is sent into irradiation precalculated position, and the focusing open country adopted in use treatment plan and radiation parameter carry out irradiation, the dosage measurement value of record reference point locations
In the trial zone that the gray scale-dose response curve of film allows, a series of radiation developed film of irradiation; Use suitable mathematical model according to the dose value of irradiation and the gray value of corresponding film, draw use the gray scale-dose response curve of film
By radiation developed film insertosome mould, body mould is sent into irradiation precalculated position, the focusing open country adopted in use treatment plan and radiation parameter carry out irradiation, apply above-mentioned gray scale-dose response curve, obtain the dose distribution of film place plane, and the area S that the isodose calculating film dosimetry distribution 50% surrounds r
The dose distribution registration that the dose distribution export above-mentioned planning system and above-mentioned film measurement obtain, and the area Sc that the isodose calculating overlap 50% therebetween surrounds
According to following formulae discovery area coincidence factor (δ s)
·
In formula:
δ s---area coincidence factor;
S r---the area of 50% isodose institute enclosing region measured by film;
S p---treatment plan calculates the area of 50% isodose institute enclosing region;
S c---overlapping area.
Equipment of the present invention and method can be applied to various body Multi-source gamma beam three-dimensional directional radiotherapy eutical system, X-ray three-dimensional directional radiotherapy eutical system, and other mode body radiotherapies are evaluated.
The foregoing is only several specific embodiment of the present invention, above embodiment is only for explaining and unrestricted right of the present invention technical scheme of the present invention and inventive concept.All technical staff in the art in conjunction with prior art, by the available other technologies scheme of logical analysis, reasoning or limited experimentation, also should be considered to drop within claims of the present invention on inventive concept basis of the present invention.

Claims (10)

1. for a test body mould for radiotherapy system, comprising: Elliptic Cylinder framework, it has inner rectangular parallelepiped space;
At least one detector plate, can just be placed in the above-mentioned rectangular parallelepiped space of Elliptic Cylinder framework.
2. body mould according to claim 1, is characterized in that, described Elliptic Cylinder framework and described detector plate with the use of time, the position of described detector plate in described Elliptic Cylinder framework can be judged by suitable labelling.
3. body mould according to claim 1, is characterized in that, described Elliptic Cylinder framework and detector plate are made up of lucite.
4. body mould according to claim 1, it is characterized in that, described detector plate comprises multiple plate that ionization chamber detector can be coordinated to use, and these plates has the perforate of different size, for coordinating different ionization chamber detector, semiconductor detector.
5. body mould according to claim 1, is characterized in that, described detector plate comprises multiple plate that radiation developed film can be coordinated to use, and these plates has and prevents radiation developed film by the cassette of visible light exposure.
6. body mould according to claim 5, is characterized in that, described cassette uses the density of impermeable visible ray to be 1g/cm substantially 3plastic material make.
7. body mould according to claim 1, is characterized in that, the rectangular parallelepiped space in described Elliptic Cylinder framework can allow to insert at least three plates simultaneously.
8. the body mould according to any one of claim 1-7, is characterized in that, described radiotherapy system is body multi-source gamma beam three-dimensional directional radiotherapy eutical system.
9. use the body mould according to any one of claim 1-8 to carry out a method for radiotherapy system test, comprise the steps:
On described radiotherapy system, use described body to be molded and make treatment plan, and export the Rapid Dose Calculation result of reference point and reference plane;
Radiation detector is positioned in described body mould;
Described body mould is positioned on described radiotherapy system therapeutic bed near focal position, frame side;
Obtain corresponding radiation dose measurement value in each measuring position, use radiation developed film to obtain corresponding Radiation dose distribution data at each measurement plane;
Measurement result and result of calculation are compared analysis, and the intended dose that obtains medical treatment calculates synthetic error and treatment plan dose distributions computation error.
10. method of testing according to claim 9, is characterized in that, described step measurement result and result of calculation being compared analysis comprises:
Read described radiotherapy system Rapid Dose Calculation data;
Obtain the absorbed dose numerical value of body ionization chamber, semiconductor detector measurement point position;
Analyze the treatment plan Rapid Dose Calculation synthetic error obtaining each measuring position;
Obtain the absorbed-dose distribution data of the radiation developed film place plane that radiotherapy system calculates;
To each measurement plane, the area that the isodose analyzing in absorbed-dose distribution data 50% surrounds and film measurement obtains 50% the area that surrounds of isodose, analyze the area of above-mentioned two areas by overlapping after registration, the coincidence factor of the area that the isodose obtaining 50% of each measurement plane surrounds.
CN201410055823.4A 2014-02-19 2014-02-19 Dose calculation error testing method of radiotherapy system and phantom Pending CN104606796A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105521568A (en) * 2016-01-27 2016-04-27 严思奇 Gyro knife dosage distribution verification method
CN111408073A (en) * 2020-03-24 2020-07-14 宁波同调医学科技有限公司 Method and system for calculating dose of radiotherapy ray planar detector
CN113599723A (en) * 2018-04-30 2021-11-05 医科达有限公司 Phantom for adaptive radiation therapy

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1163395A (en) * 1997-03-29 1997-10-29 深圳奥沃国际科技发展有限公司 Nuclear physics measuring device for stereo directional radiative therapeutic equipment
CN200951265Y (en) * 2006-08-11 2007-09-26 天津医科大学附属肿瘤医院 Radiation field measurement and isocenter testing device of radiotherapeutics equipment
CN201569746U (en) * 2009-12-25 2010-09-01 深圳市海博科技有限公司 Measuring die body

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1163395A (en) * 1997-03-29 1997-10-29 深圳奥沃国际科技发展有限公司 Nuclear physics measuring device for stereo directional radiative therapeutic equipment
CN200951265Y (en) * 2006-08-11 2007-09-26 天津医科大学附属肿瘤医院 Radiation field measurement and isocenter testing device of radiotherapeutics equipment
CN201569746U (en) * 2009-12-25 2010-09-01 深圳市海博科技有限公司 Measuring die body

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105521568A (en) * 2016-01-27 2016-04-27 严思奇 Gyro knife dosage distribution verification method
CN105521568B (en) * 2016-01-27 2019-04-19 严思奇 A kind of gyro knife dosage distribution verification method
CN113599723A (en) * 2018-04-30 2021-11-05 医科达有限公司 Phantom for adaptive radiation therapy
CN111408073A (en) * 2020-03-24 2020-07-14 宁波同调医学科技有限公司 Method and system for calculating dose of radiotherapy ray planar detector
CN111408073B (en) * 2020-03-24 2021-12-31 宁波同调医学科技有限公司 Method and system for calculating dose of radiotherapy ray planar detector

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