CN104547419A - Traditional Chinese medicine prescription for treating rheumatoid arthritis - Google Patents
Traditional Chinese medicine prescription for treating rheumatoid arthritis Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine prescription for treating rheumatoid arthritis. The traditional Chinese medicine prescription is prepared from raw traditional Chinese medicines in parts by weight as follows: 0.2-0.8 parts of musk, 1-3 parts of kusnezoff monkshood roots, 0.5-1 parts of scorpions, 1-3 parts of radix angelicae, 0.5-1 parts of ground beetles, 2-3 parts of parasitic loranthus, 2-3 parts of fructus xanthii, 2-3 parts of helwingia himalaica, 2-4 parts of lonicera japonica, 1-3 parts of roots of hairless rockvine, 2-4 parts of cortex cercis chinensis, 2-3 parts of neoalsomitra integrifolia, 2-4 parts of roots of shinyleaf pricklyash, 4-6 parts of corydalis amabilis, 2-3 parts of cortex periplocae, 2-3 parts of cortex acanthopanacis, 30-40 parts of plant oil and 15-20 parts of minium. The traditional Chinese medicine prescription is made into a plaster to cover a rheumatoid arthritis infected part, has the effects of wind and dampness elimination, muscle and tendon relaxation, blood stasis removal, pain relief, yang restoration, cold elimination, blood activation and tendon and bone strengthening through traditional Chinese medicine conditioning, takes effect quickly and has a good curative effect on rheumatoid arthritis.
Description
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly a kind of Chinese medicine formula for the treatment of rheumatism, rheumatoid arthritis.
Background technology
Rheumatism and rheumatoid are frequently-occurring disease, China and south east asia distributed more widely, prevalence is higher.Modern medicine thinks that rheumatoid arthritis is a kind of general immunity disease being principal character with synovium of joint fibrosis, bone hypertrophy and chronic polyarthritis disease.Motherland's medical science is attributed to " arthromyodynia " category it, thinks and causes the main cause of primary disease to be that wet three gas of wind and cold are mixed to and cause a disease because the positive deficiency of vital energy declines; In the treatment that its curative mechanism focuses on " general rule not bitterly, stagnation of QI and blood may bring about pain ".At present, integrative therapy generally adopts the supplementary meanss such as cooperation external treatment for oral administration to be main.The medicine of clinical treatment rheumatic Bi syndrome is many and random, there is many drawbacks, as NSAID (non-steroidal anti-inflammatory drug) ibuprofen, mainly ease pain, antiinflammatory and antipyretic, though can respite pain, namely drug withdrawal recurs, and side effect is comparatively large, often there are nausea,vomiting,diarrhea, stomachache, digestive tract ulcer and hemorrhage; Headache, dizzy, tinnitus, edema, depression, sleepy, insomnia, blurred vision, erythra etc.; Occasionally there are abnormal liver function, renal function injury, granulocyte and thrombocytopenia.Though glucocorticoid has powerful antiinflammatory action, and speed can be interrogated alleviate the symptoms such as red, swollen, hot, the pain of Bi condition; But glucocorticoid, apart from outside above-mentioned side effect, also can cause hypertension, hyperlipidemia, diabetes, osteoporosis and rebound phenomenon and withdrawal symptom.
Summary of the invention
The invention provides a kind of Chinese medicine formula for the treatment of rheumatoid arthritis, expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, stasis-dispelling and pain-killing, warming YANG to expel cold, bone and muscle strengthening, make plaster and be affixed on rheumatoid arthritis affected part, treatment rheumatism, rheumatoid arthritis, instant effect, good effect.
The Chinese medicine formula for the treatment of rheumatoid arthritis of the present invention, is characterized in that by the raw material of Chinese medicine of following parts by weight formulated:
Moschus 0.2-0.8 part, Radix Aconiti Kusnezoffii 1-3 part, Scorpio 0.5-1 part, Radix Angelicae Dahuricae 1-3 part, eupolyphaga 0.5-1 part, Herba Taxilli 2-3 part, Fructus Xanthii 2-3 part, Helwingia himalaica 2-3 part, Flos Lonicerae 2-4 part, Herba Parthenocissi Himalayanae 1-3 part, Cortex cercis chinensis 2-4 part, Rhizoma Dioscoreae Nipponicae 2-3 part, Radix Zanthoxyli Spinifolii 2-4 part, Rhizoma Corydalis Decumbentis 4-6 part, Cortex Periplocae 2-3 part, Cortex Acanthopancis 2-3 part, vegetable oil 30-40 part and Plumbum preparatium 15-20 part.
As preferably, prepare by following parts by weight:
0.5 part, Moschus (artificial Moschus), Radix Aconiti Kusnezoffii 1 part, Scorpio 0.6 part, the Radix Angelicae Dahuricae 2 parts, eupolyphaga 0.7 part, Herba Taxilli 2 parts, Fructus Xanthii 2.5 parts, Helwingia himalaica 2.5 parts, Flos Lonicerae 3 parts, Herba Parthenocissi Himalayanae 2 parts, Cortex cercis chinensis 3 parts, Rhizoma Dioscoreae Nipponicae 2.5 parts, Radix Zanthoxyli Spinifolii 3 parts, Rhizoma Corydalis Decumbentis 5 parts, Cortex Periplocae 3 parts, Cortex Acanthopancis 3 parts, vegetable oil 36 parts and 18 parts, Plumbum preparatium.
Chinese medicine of the present invention, prepare in the steps below:
(1) preprocessing: take Radix Aconiti Kusnezoffii, the Radix Angelicae Dahuricae, Herba Taxilli, Fructus Xanthii, Helwingia himalaica, Flos Lonicerae, Herba Parthenocissi Himalayanae, Cortex cercis chinensis, Rhizoma Dioscoreae Nipponicae, Radix Zanthoxyli Spinifolii, Rhizoma Corydalis Decumbentis, Cortex Periplocae and Cortex Acanthopancis section by above-mentioned parts by weight or be ground into particle diameter 0.5 ~ 1.5cm size, for subsequent use;
(2) take Moschus (artificial Moschus), Scorpio and eupolyphaga cross 120 mesh sieves after pulverizing;
(3) spice extracts: get vegetable oil and put in pot, is dropped into by raw material obtained for step (1), and heating is also constantly stirred, be heated to 220 DEG C, explode to surperficial dark brown is inner sallow until spice, fried good rear elimination medicinal residues, the oil after removing slag is medicine oil;
(4) refine oil: get above-mentioned medicine oil and continue to temper, treat that oil temperature rises to 320 DEG C, use slow fire instead, until oil bloom are assembled to pot central authorities, get a little medicine oil droplet in water, be not shattered into pearl, can stop tempering;
(5) pilling and pasting: after medicine oil is smelt, adds Plumbum preparatium in medicine oil, and limit edged stirs, and stirs into the mastic of thickness;
(6) releasing fire-toxin: the water that mastic is put into after making under room temperature soaks, changes a water each day, takes out after seven days;
(7) be mixed into the Moschus of step (2), Scorpio and eupolyphaga powder to make: get mastic and be placed in container, water-bath or slow fire are melted, Moschus, Scorpio and eupolyphaga powder are blended into, stir evenly, get with bamboo let the plaster that mastic spreads upon rheumatoid arthritis that kraft paper or plaster cloth can obtain medical treatment.
Each with above-mentioned plaster external application rheumatoid arthritis affected part, within 1 day, changing dressings 1 time, 14 days is a course for the treatment of.
Pharmacology analysis:
Moschus: warm in nature, nontoxic, bitter in the mouth.Enter the heart, spleen, Liver Channel, have the function of dredging collateral, scattered silt.Cure mainly traumatic injury, swollen ulcer drug.
Radix Aconiti Kusnezoffii Preparata: pungent, heat, very toxic.Enter liver, spleen channel, wind-damp dispelling, dispersing cold for relieving pain, detumescence.Control anemofrigid-damp arthralgia; Arthralgia; Wind syndrome of head is had a headache; Traumatic injury; Swelling and pain due to blood stasis; Carbuncle of yin nature toxic swelling; Narcotic analgesic.
Scorpio: primary medicinal component is charybdotoxin, carries according to Compendium of Material Medica and " Chinese Pharmacopoeia ", function that Scorpio has " spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., antiinflammatory counteracting toxic substances, removing obstruction in the collateral to relieve pain ".
The Radix Angelicae Dahuricae: be used as medicine with root, the functions such as the dehumidifying that gets rid of illness, evacuation of pus granulation promoting, promoting blood circulation and stopping pain.Cure mainly pain furuncle and phyma poison and wait disease, also can make spice.
Eupolyphoge sinensis: another name can steep worm, Eupolyphaga Seu Steleophaga, ground beetle, excessively street, DIWUGUI, joint joint worm, Cimex bedbug mother, eupolyphaga etc.Nature and flavor with return through: salty, cold; Slightly poisonous.Return Liver Channel.Function with cure mainly: removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.Chinese medicine function: blood stasis under (1), eliminating mass abdominal mass, treats injured: for traumatic injury and lump in the abdomen lump; (2) eliminating stasis to stop pain: for lumbar muscle strain, sprain.
Herba Taxilli: bitter in the mouth, sweet, property is put down.Liver, kidney channel.For rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable.
Fructus Xanthii: acrid in the mouth, hardship, warm in nature, poisonous.Return lung meridian.There is the function of the dehumidifying of loose wind, understand things pain-stopping.Raw Fructus Xanthii is strong with wind-repellent itching-relieving power.
Helwingia himalaica: bitter in the mouth; Pungent; Property is put down; Cure mainly rheumatic arthralgia traumatic injury congestive edema; Fracture; Carbuncle furuncle poison.
Flos Lonicerae: cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has effect of heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treatment wind, cures mainly the diseases such as pyretic toxicity carbuncle and ulcer and tumor.
Herba Parthenocissi Himalayanae: temperature, property is hidden pungent.Control traumatic injury, fracture, rheumatism.
Cortex cercis chinensis: bitter in the mouth is flat, nontoxic.Promoting blood circulation to restore menstrual flow, subduing swelling and detoxicating.Control anemofrigid-damp arthralgia, traumatic injury.
Rhizoma Dioscoreae Nipponicae: property is put down, bitter in the mouth; Return liver, lung meridian; Expelling wind and removing dampness; Promoting blood circulation to remove obstruction in the collateral.Before main air arthralgia chiefly caused by damp pathogen; Numb limbs and tense tendons; Traumatic injury.
Radix Zanthoxyli Spinifolii: pungent, temperature.Expelling wind and cold, relaxing muscles and tendons to promote blood circulation, analgesia.Dispelling the wind and dampness pathogens is numb, traumatic injury.
Rhizoma Corydalis Decumbentis: bitter in the mouth, micro-pungent, warm in nature.Liver Channel.Have promoting blood circulation and stopping pain, relaxing muscles and tendons and activating QI and blood in the collateral, expelling wind and removing dampness has effect.For injury from falling down, rheumatic arthralgia, lumbago and skelalgia.
Cortex Periplocae: nature and flavor are warm in nature, acrid in the mouth, hardship; Function cures mainly wind-damp dispelling, bone and muscle strengthening.For anemofrigid-damp arthralgia, soreness of the waist and knees, edema of lower limbs.
Cortex Acanthopancis: acrid in the mouth, hardship, warm in nature.Liver, kidney channel.There is wind-damp dispelling, liver and kidney tonifying, bone and muscle strengthening, the effect of inducing diuresis to remove edema.For Bi condition, muscles and bones flaccidity is soft, children's's walking retardation in children, and body void is weak, edema, beriberi.
Clinical case:
1, sex
Observation group: male 16 example, women 14 example.
Matched group: male 17 example, women 13 example.
2, the age
Observation group: less than 30 years old 2 example, 31-40 year 12 examples, 41-50 year 8 examples, 51-60 year 5 examples, more than 61 years old 3 is routine.Max age 65 years old, minimal ages 23 years old, the mean age is 47 years old.
Matched group: less than 30 years old 2 example, 31-40 year 9 example, 41-50 year 11 example, 51-60 year 8 example, max age 62 years old, minimal ages 21 years old, the mean age is 46 years old.
3, the course of disease
Observation group: more than 1 year 14 example, 2-3 7 example, 3-4 6 example, 4-5 2 example, more than 5 years 1 examples, the longest course of disease is 5 years, and the shortest course of disease is 40 days, average course of disease 1.8 years.
Matched group: more than 1 year 11 example, 2-3 12 example, 3-4 7 example, the longest course of disease is 3 years, and the shortest course of disease is 3 days, average course of disease 1.4 years.
4, sick kind is observed
Observation group: rheumatoid arthritis 22 example, psoas muscle fibrositis 3 example, the routine right ankle arthritis of scapulohumeral periarthritis 3, each 1 example of knee hyperplasia.
Matched group: rheumatoid arthritis 21 example, psoas muscle fibrositis 3 example, each 3 examples of scapulohumeral periarthritis, rheumatalgia.
Two, case selection standard
(1) the dialectical standard of tcm diagnosis
Rheumatalgia symptom
(1) main clinical manifestation: the tract pain such as joint, skin, muscles and bones, or pain is altered in migration, or miserablely to swell and ache, or swelling is stiff for morning, numbness weighs, or stretch unfavorable etc.
(2) the dim white, slippery and moist fur of matter is greasy, stringy and rolling pulse or slow.
(3) characteristics of incidence: outbreak can be relevant with climate change.
Possesses the tongue arteries and veins of any primary symptom and (2) item in above-mentioned (1) item, in conjunction with (3) item and diagnosable.
(2) Western medicine diagnose
The disease of the Western medicine diagnose that all above-mentioned Chinese medical discriminations can relate to, performs by the newest standards of this disease, makes corresponding Western medicine diagnose.
(1) pain degree classification
1, slight (+): pain is accidental, or has a dull ache, or time movable, slightly feel pain or bitterly remarkable, there is slight tenderness local, does not affect daily life or work.
2, moderate (++): pain is obvious, or continuously to take place frequently, movable unfavorable and pain increases the weight of, and even affects orthobiosis and work.
3, severe (+++): sharp ache, stiff, slightly dynamic severe pain, can not adhere to normal work and life.
(2) function of joint activity classification
1, slightly limited (+): one or several joint, muscles and bones is movable uncomfortable, or gentle activity is unfavorable, but can be engaged in various normal activity.
2, moderate limited (++): affected joints muscles and bones limitation of activity, effort activity then bears affliction, and life can be taken care of oneself, still can normal activity
3, severe limited (+++): joint, muscles and bones are stiff, tetanic, stiff, can't take care of oneself and maybe need bed or sitting and lying.
Above-mentioned classification is as without obvious pain or limited without obvious joint, or pain disappears or the limited releasing in joint be then feminine gender (-) after treatment.
Three, inapplicable the present invention tests case standard
1, the age is under-18s and more than 70 years old person, gestation or women breast-feeding their children, those who are allergic to this drug.
2, medication local suffers from severe skin disease or obviously skin lesion and wound, affects medication person.
3, other serious joint disease and psychotics.
4, do not meet inclusive criteria, not by regulation medication, the not congruent person of affecting the treatment of curative effect or data cannot be judged.
Four, observation index
(1) local symptom such as joint, skin, muscles and bones, as pain, numbness, cool, stiff, miserable, the symptom variation situations such as swelling.
(2) erythrocyte sedimentation rate can be surveyed if desired, or anti-chain " 0 " etc.
Five, verification method:
(1) observation group: the plaster that 30 exception the present invention make, external, every day one pastes, and spreads on affected part.Treat 3 courses for the treatment of.
(2) matched group: 30 examples, external ZHENGHONGHUA YOU, every day 2 times, embrocates affected part.Treat 3 courses for the treatment of.
Six, curative effect statistics:
| Total number of cases | Invalid | Effective | Cure | Effective percentage % | Cure rate % | |
| Observation group | 30 | 2 | 21 | 7 | 93.3 | 23％ |
| Matched group | 30 | 6 | 21 | 3 | 80.0 | 10％ |
Moschus in formula of the present invention, Radix Aconiti Kusnezoffii, Scorpio, the Radix Angelicae Dahuricae, eupolyphaga, Herba Taxilli, Fructus Xanthii, Helwingia himalaica, Flos Lonicerae, Herba Parthenocissi Himalayanae, Cortex cercis chinensis, Rhizoma Dioscoreae Nipponicae, Radix Zanthoxyli Spinifolii heat-clearing and toxic substances removing, expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, the cold expelling that induces sweat, eliminating stasis to stop pain, be aided with Rhizoma Corydalis Decumbentis blood circulation promoting and blood stasis dispelling, recuperating depleted YANG cold expelling, Cortex Periplocae and Cortex Acanthopancis bone and muscle strengthening, make plaster and be affixed on affected part, treatment rheumatoid arthritis, instant effect, good effect.
Detailed description of the invention
Embodiment 1
0.5 part, Moschus, Radix Aconiti Kusnezoffii 1 part, Scorpio 0.6 part, the Radix Angelicae Dahuricae 2 parts, eupolyphaga 0.7 part, Herba Taxilli 2 parts, Fructus Xanthii 2.5 parts, Helwingia himalaica 2.5 parts, Flos Lonicerae 3 parts, Herba Parthenocissi Himalayanae 2 parts, Cortex cercis chinensis 3 parts, Rhizoma Dioscoreae Nipponicae 2.5 parts, Radix Zanthoxyli Spinifolii 3 parts, Rhizoma Corydalis Decumbentis 5 parts, Cortex Periplocae 3 parts, Cortex Acanthopancis 3 parts, 18 parts, the good Plumbum preparatium of vegetable oil 36 parts.
Chinese medicine formula of the present invention, prepare as follows and use:
(1) preprocessing: take Radix Aconiti Kusnezoffii, the Radix Angelicae Dahuricae, Herba Taxilli, Fructus Xanthii, Helwingia himalaica, Flos Lonicerae, Herba Parthenocissi Himalayanae, Cortex cercis chinensis, Rhizoma Dioscoreae Nipponicae, Radix Zanthoxyli Spinifolii, Rhizoma Corydalis Decumbentis, Cortex Periplocae and Cortex Acanthopancis by above-mentioned parts by weight, cut into slices or be ground into particle diameter 1cm size, for subsequent use;
(2) take Moschus, Scorpio and eupolyphaga, after pulverizing, cross 120 mesh sieves;
(3) spice extracts: get vegetable oil and put in pot, is dropped into by raw material obtained for step (1), and heating is also constantly stirred, be heated to 220 DEG C, explode to surperficial dark brown is inner sallow until spice, fried good rear elimination medicinal residues, the oil after removing slag is medicine oil;
(4) refine oil: get above-mentioned medicine oil and continue to temper, treat that oil temperature rises to 320 DEG C, use slow fire instead, until oil bloom are assembled to pot central authorities, get a little medicine oil droplet in water, be not shattered into pearl, can stop tempering;
(5) pilling and pasting: after medicine oil is smelt, adds Plumbum preparatium in medicine oil, and limit edged stirs, and stirs into the mastic of thickness;
(6) releasing fire-toxin: the water that mastic is put into after making under room temperature soaks, changes a water each day, takes out after seven days;
(7) be mixed into the Moschus of step (2), Scorpio and eupolyphaga powder to make: get mastic and be placed in container, water-bath or slow fire are melted, Moschus, Scorpio and eupolyphaga powder are blended into, stir evenly, get with bamboo let the plaster that mastic spreads upon rheumatoid arthritis that kraft paper or plaster cloth can obtain medical treatment.
Each with above-mentioned plaster external application rheumatoid arthritis affected part, within 1 day, changing dressings 1 time, 14 days is a course for the treatment of.
Claims (2)
1. treat a Chinese medicine formula for rheumatoid arthritis, it is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Moschus 0.2-0.8 part, Radix Aconiti Kusnezoffii 1-3 part, Scorpio 0.5-1 part, Radix Angelicae Dahuricae 1-3 part, eupolyphaga 0.5-1 part, Herba Taxilli 2-3 part, Fructus Xanthii 2-3 part, Helwingia himalaica 2-3 part, Flos Lonicerae 2-4 part, Herba Parthenocissi Himalayanae 1-3 part, Cortex cercis chinensis 2-4 part, Rhizoma Dioscoreae Nipponicae 2-3 part, Radix Zanthoxyli Spinifolii 2-4 part, Rhizoma Corydalis Decumbentis 4-6 part, Cortex Periplocae 2-3 part, Cortex Acanthopancis 2-3 part, vegetable oil 30-40 part and Plumbum preparatium 15-20 part.
2. the Chinese medicine formula for the treatment of rheumatoid arthritis according to claim 1, is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: 0.5 part, Moschus, Radix Aconiti Kusnezoffii 1 part, Scorpio 0.6 part, the Radix Angelicae Dahuricae 2 parts, eupolyphaga 0.7 part, Herba Taxilli 2 parts, Fructus Xanthii 2.5 parts, Helwingia himalaica 2.5 parts, Flos Lonicerae 3 parts, Herba Parthenocissi Himalayanae 2 parts, Cortex cercis chinensis 3 parts, Rhizoma Dioscoreae Nipponicae 2.5 parts, Radix Zanthoxyli Spinifolii 3 parts, Rhizoma Corydalis Decumbentis 5 parts, Cortex Periplocae 3 parts, Cortex Acanthopancis 3 parts, vegetable oil 36 parts and 18 parts, Plumbum preparatium.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104971223A (en) * | 2015-06-15 | 2015-10-14 | 李蒋萍 | External traditional Chinese medicine for treating rheumatoid arthritis |
| CN105561186A (en) * | 2015-12-31 | 2016-05-11 | 张茂全 | Traditional Chinese medicine formula for treating rheumatoid arthritis |
| CN108066694A (en) * | 2016-11-15 | 2018-05-25 | 程兵建 | A kind of Chinese medicine composition for being used to treat rheumatic arthritis |
| CN114224144A (en) * | 2021-12-27 | 2022-03-25 | 贵州紫日茶业科技有限公司 | Medicinal tea pillow for assisting seedlings of rheumatic diseases and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101352503A (en) * | 2008-08-27 | 2009-01-28 | 杨振才 | Plaster for treating joint ache and preparation method thereof |
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2014
- 2014-12-26 CN CN201410836374.7A patent/CN104547419A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101352503A (en) * | 2008-08-27 | 2009-01-28 | 杨振才 | Plaster for treating joint ache and preparation method thereof |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104971223A (en) * | 2015-06-15 | 2015-10-14 | 李蒋萍 | External traditional Chinese medicine for treating rheumatoid arthritis |
| CN105561186A (en) * | 2015-12-31 | 2016-05-11 | 张茂全 | Traditional Chinese medicine formula for treating rheumatoid arthritis |
| CN108066694A (en) * | 2016-11-15 | 2018-05-25 | 程兵建 | A kind of Chinese medicine composition for being used to treat rheumatic arthritis |
| CN114224144A (en) * | 2021-12-27 | 2022-03-25 | 贵州紫日茶业科技有限公司 | Medicinal tea pillow for assisting seedlings of rheumatic diseases and preparation method thereof |
| CN114224144B (en) * | 2021-12-27 | 2023-08-18 | 贵州紫日茶业科技有限公司 | Auxiliary Miao medicine tea pillow for rheumatic diseases and preparation method thereof |
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Application publication date: 20150429 |