CN104511002B - 一种抗风湿抗类风湿止痛药物 - Google Patents
一种抗风湿抗类风湿止痛药物 Download PDFInfo
- Publication number
- CN104511002B CN104511002B CN201410177039.0A CN201410177039A CN104511002B CN 104511002 B CN104511002 B CN 104511002B CN 201410177039 A CN201410177039 A CN 201410177039A CN 104511002 B CN104511002 B CN 104511002B
- Authority
- CN
- China
- Prior art keywords
- parts
- antirheumatic
- drug product
- analgesic drug
- rheumatoid disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 201000010099 disease Diseases 0.000 title claims abstract description 38
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims abstract description 38
- 239000000730 antalgic agent Substances 0.000 title claims abstract description 27
- 230000003356 anti-rheumatic effect Effects 0.000 title claims abstract description 27
- 239000003435 antirheumatic agent Substances 0.000 title claims abstract description 27
- 229940035676 analgesics Drugs 0.000 title claims abstract description 26
- 239000003814 drug Substances 0.000 claims abstract description 23
- 241000026010 Dendrobium candidum Species 0.000 claims abstract description 15
- 241000427159 Achyranthes Species 0.000 claims abstract description 10
- 241001465251 Ephedra sinica Species 0.000 claims abstract description 9
- 241000212321 Levisticum Species 0.000 claims abstract description 9
- 244000241872 Lycium chinense Species 0.000 claims abstract description 9
- 235000015468 Lycium chinense Nutrition 0.000 claims abstract description 9
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 9
- 239000000463 material Substances 0.000 claims description 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 11
- 238000002156 mixing Methods 0.000 claims description 10
- 238000001914 filtration Methods 0.000 claims description 8
- 235000012907 honey Nutrition 0.000 claims description 7
- 230000008030 elimination Effects 0.000 claims description 6
- 238000003379 elimination reaction Methods 0.000 claims description 6
- 239000012535 impurity Substances 0.000 claims description 6
- 238000002360 preparation method Methods 0.000 claims description 3
- 208000002193 Pain Diseases 0.000 abstract description 15
- 230000036407 pain Effects 0.000 abstract description 15
- 230000000694 effects Effects 0.000 abstract description 11
- 230000008961 swelling Effects 0.000 abstract description 5
- 230000003213 activating effect Effects 0.000 abstract description 3
- 239000012530 fluid Substances 0.000 abstract description 3
- 230000002040 relaxant effect Effects 0.000 abstract description 3
- 210000002435 tendon Anatomy 0.000 abstract description 3
- 230000001050 lubricating effect Effects 0.000 abstract description 2
- 231100000957 no side effect Toxicity 0.000 abstract description 2
- 208000025747 Rheumatic disease Diseases 0.000 abstract 1
- 230000000552 rheumatic effect Effects 0.000 abstract 1
- 208000006820 Arthralgia Diseases 0.000 description 8
- 229940079593 drug Drugs 0.000 description 7
- 208000024891 symptom Diseases 0.000 description 7
- 238000000034 method Methods 0.000 description 5
- 230000000857 drug effect Effects 0.000 description 4
- 210000000629 knee joint Anatomy 0.000 description 4
- 210000003205 muscle Anatomy 0.000 description 4
- 239000002994 raw material Substances 0.000 description 4
- 210000001624 hip Anatomy 0.000 description 3
- 230000036039 immunity Effects 0.000 description 3
- 210000001503 joint Anatomy 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 210000001367 artery Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- 210000003414 extremity Anatomy 0.000 description 2
- 210000002683 foot Anatomy 0.000 description 2
- 210000003127 knee Anatomy 0.000 description 2
- 208000024765 knee pain Diseases 0.000 description 2
- 231100000862 numbness Toxicity 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 208000036487 Arthropathies Diseases 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 240000004638 Dendrobium nobile Species 0.000 description 1
- 235000002710 Ilex cornuta Nutrition 0.000 description 1
- 241001310146 Ilex cornuta Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000012659 Joint disease Diseases 0.000 description 1
- 206010023232 Joint swelling Diseases 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 244000241838 Lycium barbarum Species 0.000 description 1
- 235000015459 Lycium barbarum Nutrition 0.000 description 1
- 206010027336 Menstruation delayed Diseases 0.000 description 1
- 208000000112 Myalgia Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 235000010326 Osmanthus heterophyllus Nutrition 0.000 description 1
- 244000131316 Panax pseudoginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 206010034464 Periarthritis Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 210000003423 ankle Anatomy 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 235000011194 food seasoning agent Nutrition 0.000 description 1
- 230000005176 gastrointestinal motility Effects 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 210000005067 joint tissue Anatomy 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 230000003119 painkilling effect Effects 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 229960002895 phenylbutazone Drugs 0.000 description 1
- VYMDGNCVAMGZFE-UHFFFAOYSA-N phenylbutazonum Chemical compound O=C1C(CCCC)C(=O)N(C=2C=CC=CC=2)N1C1=CC=CC=C1 VYMDGNCVAMGZFE-UHFFFAOYSA-N 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 210000003371 toe Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 210000000707 wrist Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8984—Dendrobium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种抗风湿抗类风湿止痛药物，涉及风湿保健用品领域，制成该药物的重要成分及重量比例为：铁皮石斛8~30份，麻黄7~25份，枸杞子5~20份，海风藤7~25份，干姜6~24份，甘草3~20份，牛膝4~25份，独活6~24份，苍术5~24份。本发明能够滋养阴液、润滑关节、消肿止痛、舒筋活血，对风湿类风湿有良好的效果，疗程短，见效快，无副作用。
Description
技术领域
本发明涉及抗风湿保健品领域，特别是一种抗风湿抗类风湿止痛药物。
背景技术
类风湿病是一种常见的多发病，属于祖国医学“痹症”范畴，类风湿是以关节病变为主的慢性全身性免疫性疾病，是一种以关节滑膜炎为特征的慢性疾病。关节各部分均可受到侵犯，该病好发于手、腕、足等小关节，反复发作，呈对称分布，发病早期表现的症状为关节红肿、热、痛和活动不方便等等现象，晚期则可出现不同程度的僵硬畸形，丧失劳动能力甚至致残。
铁皮石斛是我国传统名贵中药材，民间就有“北有人参，南有石斛”之说，具有不凡的药用价值，为历代皇室贵族的养生滋补珍品。现代药理研究还表明：铁皮石斛具有预防风湿、抗风湿、活血通筋，止痛的功效。
风湿病是一种临床常见病、多发病、发病周期较长，临床症状表现多样，治疗期较长的顽固性疾病。当前，对于该种疾病西医治疗常用水杨酸类制剂、保泰松、以及激素等药物，多以缓解症状为主，疗效不能巩固，且副作用大。本发明主要用于治疗和缓解类风湿引起的各种疼痛，效果良好，无副作用。
发明内容
本发明的目的在于：针对上述存在的问题，提供了一种抗类风湿抗类风湿止痛药物，主要以铁皮石斛的药效为主，具有舒筋活血，祛风除湿。用于风寒湿痹，四肢麻木，筋膜炎，筋骨疼痛，步行艰难，对治疗风湿、类风湿引起的关节炎，颈椎、腰椎、肩周炎，腰腿疼痛，关节肿胀，四肢麻木疗效显著，无毒副作用。
本发明采用技术方案如下：
一种抗风湿抗类风湿止痛药物，由以下重量份药材组成：铁皮石斛8～30份，麻黄7～25份，枸杞子5～20份，海风藤7～25份，干姜6～24份，甘草3～20份，牛膝4～25份，独活6～24份，苍术5～24份。
作为本发明的优选方案，所述药物由以下重量份药材组成：铁皮石斛9～27份，麻黄10～23份，枸杞子6～18份，海风藤8～20份，干姜8～22份，甘草5～17份，牛膝5～20份，独活7～20份，苍术6～20份。
该药物的制备方法：取上述9味药材，洗净去杂，晒干，切成小块；将切成小块的药材加入药材5倍量的水，煎煮1～2个小时，取其煎液，过滤，得到第一份药液，第二次再加入3～4倍的水，煎煮1.5个小时，取出药液，和第一份药液混合，过滤；往上述所得的药液添加适量的蜂蜜混匀，装瓶，冷冻24小时，制得抗风湿抗类风湿治痛药物。
本发明一种抗风湿抗类风湿止痛药物，用上述的方法制备而成的药物仅供口服，每日三次，每次50ml，半个月为一个疗程。
本口服液的配方中，各组分的功效为：铁皮石斛自古以来都是具有很高要用价值的中药，铁皮石斛能够滋养阴液、润滑关节、镇痛、舒筋活血、祛风除湿等功效；麻黄发汗散寒、利水消肿；枸杞子可治疗肝肾阴亏、腰膝酸软、可调节机体免疫功能；海风藤祛风湿、通经络、止痹痛，主要用于风寒湿痹，肢节疼痛，筋脉拘挛，屈伸不利；干姜温中散寒，回阳通脉，主治寒湿痹痛；甘草补脾益气缓急止痛，调和诸药；牛膝补肝肾、强筋骨、逐疗通经、引血下行；独活治风寒湿痹、腰膝酸痛、手脚挛痛；苍术调整胃肠运动功能、燥湿健脾、祛风除湿的功效；蜂蜜有调味，补中润燥作用。
综上所述，采用了上述的技术方案，本发明的有益效果是：该药物采用传统的中药配制而成，配方合理，遵循“君、臣、佐、使”原则，以铁皮石 斛的药效为主及滋养阴液、润滑关节，消肿止痛，和其他药材混合药效更佳，根据类风湿病病因，对症下药，其药效相辅相成，服用后手、足、踝、膝、腰等关节能快速的吸收。本发明的药材组合能祛风止痛、活血化瘀强筋壮骨、疏通关节循环障碍、促进关节组织新生的功效，同时还可调节机体免疫功能、无副作用。
具体实施方式
现结合实施例对本发明技术方案进行进一步说明：
实施例1
一种抗风湿抗类风湿止痛药物由以下重量份配比原料组成：铁皮石斛8份，麻黄10份，枸杞子5份，海风藤7份，干姜7份，甘草5份，牛膝4份，独活10份，苍术10份。取上述9味药材，洗净去杂，晒干，切成小块；将切成小块的药材加入药材5倍量的水，煎煮1～2个小时，取其煎液，过滤，得到第一份药液，第二次再加入3～4倍的水，煎煮1.5个小时，取出药液，和第一份药液混合，过滤；往上述所得的药液添加适量的蜂蜜混匀，装瓶，冷冻24小时，制得抗风湿抗类风湿止痛药物。
本发明的抗风湿抗类风湿止痛药物，用上述的方法制备而成的药液仅供口服，每日三次，每次50ml，半个月为一个疗程。
实施例2
一种抗风湿抗类风湿止痛药物由以下重量份配比原料组成：铁皮石斛10份，麻黄20份，枸杞子15份，海风藤25份，干姜20份，甘草20份，牛膝10份，独活24份，苍术15份。取上述9味药材，洗净去杂，晒干，切成小块；将切成小块的药材加入药材5倍量的水，煎煮1～2个小时，取其煎液，过滤，得到第一份药液，第二次再加入3～4倍的水，煎煮1.5个小时，取出药液， 和第一份药液混合，过滤；往上述所得的药液添加适量的蜂蜜混匀，装瓶，冷冻24小时，制得抗风湿抗类风湿止痛药物。
本发明的抗风湿抗类风湿止痛药物，用上述的方法制备而成的药液仅供口服，每日三次，每次50ml，半个月为一个疗程。
实施例3
抗风湿抗类风湿止痛药物由以下重量份配比原料组成：铁皮石斛9份，麻黄9份，枸杞子8份，海风藤8份，干姜20份，甘草15份，牛膝5份，独活10份，苍术6份。取上述9味药材，洗净去杂，晒干，切成小块；将切成小块的药材加入药材5倍量的水，煎煮1～2个小时，取其煎液，过滤，得到第一份药液，第二次再加入3～4倍的水，煎煮1.5个小时，取出药液，和第一份药液混合，过滤；往上述所得的药液添加适量的蜂蜜混匀，装瓶，冷冻24小时，制得抗风湿抗类风湿止痛药物。
本发明的抗风湿抗类风湿止痛药物，用上述的方法制备而成的药液仅供口服，每日三次，每次50ml，半个月为一个疗程。
实施例4
抗风湿抗类风湿止痛药物由以下重量份配比原料组成：铁皮石斛27份，麻黄23份，枸杞子15份，海风藤20份，干姜15份，甘草17份，牛膝15份，独活15份，苍术20份。取上述9味药材，洗净去杂，晒干，切成小块；将切成小块的药材加入药材5倍量的水，煎煮1～2个小时，取其煎液，过滤，得到第一份药液，第二次再加入3～4倍的水，煎煮1.5个小时，取出药液，和第一份药液混合，过滤；往上述所得的药液添加适量的蜂蜜混匀，装瓶，冷冻24小时，制得抗风湿抗类风湿止痛药物。
本发明的抗风湿抗类风湿止痛药物，用上述的方法制备而成的药液仅供口服，每日三次，每次50ml，半个月为一个疗程。
治疗例1
黄某，女，60岁，用药前症状：患类风湿病十多年，长期服用其他药物治疗无效，全身关节疼痛，关节障碍，行动不便，病情严重。2013年10月开始服用本发明的抗风湿抗类风湿止痛药物实施例1的调剂的药液三个疗程后关节肿痛消失，行动方便，病情得到控制。
治疗例2
李某，男，54岁，用药前症状：风湿腰痛、膝盖疼痛4年，2012年8月开始服用本发明的抗风湿抗类风湿止痛药物实施例2调剂的药液治疗两周后腰痛、膝盖疼痛得到明显的控制。
治疗例3
高某，女，47岁，用药前症状：膝关节酸软痛，医院诊断为风湿痛，2013年6月服用本发明的抗风湿抗类风湿止痛药物实施例3调剂的药液治疗两个疗程后，酸软痛明显消失。
治疗例4
陈某，男，34岁，用药前症状：手、足趾关节肿痛，膝关节酸软痛，诊断为风湿痛，2010年3月服用本发明的抗风湿抗类风湿止痛药物实施例4调剂的药液治疗三个疗程后关节肿痛消失，膝关节酸痛明显好转。
Claims (3)
1.一种抗风湿抗类风湿止痛药物，其特征在于：由以下重量份药材组成：铁皮石斛8～30份，麻黄7～25份，枸杞子5～20份，海风藤7～25份，干姜6～24份，甘草3～20份，牛膝4～25份，独活6～24份，苍术5～24份。
2.根据权利要求1所述的一种抗风湿抗类风湿止痛药物，其特征在于：由以下重量份药材组成：铁皮石斛9～27份，麻黄10～23份，枸杞子6～18份，海风藤8～20份，干姜8～22份，甘草5～17份，牛膝5～20份，独活7～20份，苍术6～20份。
3.根据权利要求1～2任一项所述的一种抗风湿抗类风湿止痛药物的制备方法，其特征在于：包括以下步骤：
1)取上述9味药材，洗净去杂，晒干，切成小块；
2)将切成小块的药材加入药材5倍量的水，煎煮1～2个小时，取其煎液，过滤，得到第一份药液，第二次再加入3～4倍的水，煎煮1.5个小时，取出药液，和第一份药液混合，过滤；
3)往步骤2所得的药液添加适量的蜂蜜混匀，装瓶，冷冻24小时，制得抗风湿抗类风湿止痛药物。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410177039.0A CN104511002B (zh) | 2014-04-29 | 2014-04-29 | 一种抗风湿抗类风湿止痛药物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410177039.0A CN104511002B (zh) | 2014-04-29 | 2014-04-29 | 一种抗风湿抗类风湿止痛药物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104511002A CN104511002A (zh) | 2015-04-15 |
| CN104511002B true CN104511002B (zh) | 2017-11-24 |
Family
ID=52787240
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410177039.0A Expired - Fee Related CN104511002B (zh) | 2014-04-29 | 2014-04-29 | 一种抗风湿抗类风湿止痛药物 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104511002B (zh) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107648528B (zh) * | 2017-11-24 | 2021-04-13 | 福建拓天生物科技有限公司 | 一种含铁皮石斛的中药组合物及其制备方法与应用 |
| CN108310227A (zh) * | 2018-04-01 | 2018-07-24 | 张奉明 | 一种有益骨关节健康的铁皮石斛组合物及其制备方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1435198A (zh) * | 2002-01-31 | 2003-08-13 | 张学成 | 一种专治风湿病的特效蒙药丸 |
| CN1695697A (zh) * | 2005-06-03 | 2005-11-16 | 李伟阳 | 一种治疗风湿性关节炎疼痛的药物 |
| CN101972467A (zh) * | 2010-11-15 | 2011-02-16 | 张军 | 治疗风湿筋骨痛的中药液及制备方法与使用方法 |
-
2014
- 2014-04-29 CN CN201410177039.0A patent/CN104511002B/zh not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1435198A (zh) * | 2002-01-31 | 2003-08-13 | 张学成 | 一种专治风湿病的特效蒙药丸 |
| CN1695697A (zh) * | 2005-06-03 | 2005-11-16 | 李伟阳 | 一种治疗风湿性关节炎疼痛的药物 |
| CN101972467A (zh) * | 2010-11-15 | 2011-02-16 | 张军 | 治疗风湿筋骨痛的中药液及制备方法与使用方法 |
Non-Patent Citations (4)
| Title |
|---|
| 冯兴华运用四神煎治疗类风湿关节炎经验;曹炜等;《中国中医药信息杂志》;20080515;第15卷(第05期);第91-92页 * |
| 用药心得录;王健;《江苏中医药》;19930930(第09期);第35页 * |
| 自拟石斛利膝汤治疗鹤膝风49例;杨常青;《实用中医内科杂志》;20050405;第19卷(第02期);第131页 * |
| 风湿病中医临床思维;刘健;《中医药临床杂志》;20100910;第22卷(第09期);第753-761页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104511002A (zh) | 2015-04-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103599255B (zh) | 痛风药酒 | |
| CN103211932B (zh) | 一种治疗风湿痹症的中药组合物 | |
| CN104771740A (zh) | 一种治疗风湿性关节炎的中药组合物 | |
| CN102058802A (zh) | 一种治疗风湿性关节炎的中药组方 | |
| CN102872226B (zh) | 一种治疗痹症的中药组合物 | |
| CN102872301B (zh) | 抗风湿药酒及其使用方法 | |
| CN104511002B (zh) | 一种抗风湿抗类风湿止痛药物 | |
| CN104758743A (zh) | 一种治疗风湿病的中药泡脚粉及其制备和使用方法 | |
| CN103495126A (zh) | 一种治疗风湿病的中药组合物 | |
| CN104491642A (zh) | 一种防治痛风的足浴粉剂 | |
| CN107551061B (zh) | 补气血复阳胶囊 | |
| CN102526275B (zh) | 一种用于治疗痛风的药物及其制备方法 | |
| CN103127349B (zh) | 一种治疗跌打损伤的药物 | |
| CN103585589B (zh) | 一种治疗慢性类风湿性关节炎的药物 | |
| CN102512585A (zh) | 一种治疗阴虚火旺的中药组合物 | |
| CN101987128A (zh) | 治疗荨麻疹的中药制剂 | |
| CN101502604B (zh) | 一种治疗风湿病的中草药制剂 | |
| CN105311520A (zh) | 一种治疗跌打损伤中药搽剂 | |
| CN104491818A (zh) | 风湿性类风湿性关节炎治疗配方及其制备方法 | |
| CN102188566B (zh) | 一种治疗坐骨神经痛药酒 | |
| CN106214870A (zh) | 一种治疗风湿关节炎的足浴粉及其制备方法 | |
| CN106620013A (zh) | 一种治疗风湿关节炎的足浴粉及其制备方法 | |
| CN103550620A (zh) | 一种治疗风湿疼痛的外用药物组合物 | |
| CN105687917A (zh) | 一种治疗关节炎的口服液 | |
| CN106075344A (zh) | 一种治疗中风偏瘫的中药药酒及其制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20171124 Termination date: 20180429 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |